FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

John Wilson

Research Profile

Chemicals & Drugs

Living Beings

Anatomy

Physiology

Biological Transport

Disorders

Co-author Network

Publications

TOP 3
Gang Zhou; George Kamenos; Suresh Pendem; John X Wilson; Feng Wu
Ascorbate protects against vascular leakage in cecal ligation and puncture-induced septic peritonitis.
John X Wilson; F Wu
Vitamin C in sepsis.
Min Han; Suresh Pendem; Suet Ling Teh; Dinesh K Sukumaran; Feng Wu; John X Wilson
Ascorbate protects endothelial barrier function during septic insult: Role of protein phosphatase type 2A.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of John Wilson (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2012: Gang Zhou; George Kamenos; Suresh Pendem; John X Wilson; Feng Wu
Ascorbate protects against vascular leakage in cecal ligation and puncture-induced septic peritonitis.
American journal of physiology. Regulatory, integrative and comparative physiology 2012;302(4):R409-16.
2012: John X Wilson; F Wu
Vitamin C in sepsis.
Sub-cellular biochemistry 2012;56():67-83.
2010: Min Han; Suresh Pendem; Suet Ling Teh; Dinesh K Sukumaran; Feng Wu; John X Wilson
Ascorbate protects endothelial barrier function during septic insult: Role of protein phosphatase type 2A.
Free radical biology & medicine 2010;48(1):128-35.
2009: Feng Wu; Min Han; John X Wilson
Tripterine prevents endothelial barrier dysfunction by inhibiting endogenous peroxynitrite formation.
British journal of pharmacology 2009;157(6):1014-23.
2009: Patrick W Pace; Li-Juan Yao; John X Wilson; Fred Possmayer; Ruud A W Veldhuizen; James F Lewis
The effects of hyperoxia exposure on lung function and pulmonary surfactant in a rat model of acute lung injury.
Experimental lung research 2009;35(5):380-98.
2009: John X Wilson
Mechanism of action of vitamin C in sepsis: ascorbate modulates redox signaling in endothelium.
BioFactors (Oxford, England) 2009;35(1):5-13.
2008: Feng Wu; Karel Tyml; John X Wilson
iNOS expression requires NADPH oxidase-dependent redox signaling in microvascular endothelial cells.
Journal of cellular physiology 2008;217(1):207-14.
2008: Karel Tyml; Fuyan Li; John X Wilson
Septic impairment of capillary blood flow requires nicotinamide adenine dinucleotide phosphate oxidase but not nitric oxide synthase and is rapidly reversed by ascorbate through an endothelial nitric oxide synthase-dependent mechanism.
Critical care medicine 2008;36(8):2355-62.
2008: Julia Ip; John X Wilson; Jack P Uetrecht
Testing the hypothesis that vitamin C deficiency is a risk factor for clozapine-induced agranulocytosis using guinea pigs and ODS rats.
Chemical research in toxicology 2008;21(4):869-73.
2007: Feng Wu; David P Schuster; Karel Tyml; John X Wilson
Ascorbate inhibits NADPH oxidase subunit p47phox expression in microvascular endothelial cells.
Free radical biology & medicine 2007;42(1):124-31.
2006: Kim A Davis; Sue E Samson; John X Wilson; Ashok K Grover
Hypotonic shock stimulates ascorbate release from coronary artery endothelial cells by a Ca2+ -independent pathway.
European journal of pharmacology 2006;548(1-3):36-44.
2006: Magdalena Dragan; S Jeffrey Dixon; Ewa Jaworski; Tom Chan; Peter J O'Brien; John X Wilson
Coenzyme Q(1) depletes NAD(P)H and impairs recycling of ascorbate in astrocytes.
Brain research 2006;1078(1):9-18.
2006: Kim A Davis; Sue E Samson; Kelly Best; Kanwaldeep K Mallhi; Magdalena M Szewczyk; John X Wilson; Chiu-Yin Kwan; Ashok K Grover
Ca2+-mediated ascorbate release from coronary artery endothelial cells.
British journal of pharmacology 2006;147(2):131-9.
2005: John X Wilson; Magdalena Dragan
Sepsis inhibits recycling and glutamate-stimulated export of ascorbate by astrocytes.
Free radical biology & medicine 2005;39(8):990-8.
2005: Shiu-Ming Kuo; Chee-Ho Tan; Magdalena Dragan; John X Wilson
Endotoxin increases ascorbate recycling and concentration in mouse liver.
The Journal of nutrition 2005;135(10):2411-6.
2005: Karel Tyml; Fuyan Li; John X Wilson
Delayed ascorbate bolus protects against maldistribution of microvascular blood flow in septic rat skeletal muscle.
Critical care medicine 2005;33(8):1823-8.
2005: Guowei Huang; Magdalena Dragan; David Freeman; John X Wilson
Activation of catechol-O-methyltransferase in astrocytes stimulates homocysteine synthesis and export to neurons.
Glia 2005;51(1):47-55.
2005: Tom Chan; Nandita Shangari; John X Wilson; Helen Chan; Roger F Butterworth; Peter J O'Brien
The biosynthesis of ascorbate protects isolated rat hepatocytes from cumene hydroperoxide-mediated oxidative stress.
Free radical biology & medicine 2005;38(7):867-73.
2005: Kelly Best; Melanie E Holmes; Sue E Samson; James Mwanjewe; John X Wilson; S Jeffrey Dixon; Ashok K Grover
Ascorbate uptake in pig coronary artery endothelial cells.
Molecular and cellular biochemistry 2005;271(1-2):43-9.
2005: John X Wilson
Regulation of vitamin C transport.
Annual review of nutrition 2005;25():105-25.
2004: Feng Wu; John X Wilson; Karel Tyml
Ascorbate protects against impaired arteriolar constriction in sepsis by inhibiting inducible nitric oxide synthase expression.
Free radical biology & medicine 2004;37(8):1282-9.
2004: Shiu-Ming Kuo; Marlene E MacLean; Kathleen McCormick; John X Wilson
Gender and sodium-ascorbate transporter isoforms determine ascorbate concentrations in mice.
The Journal of nutrition 2004;134(9):2216-21.
2004: S Jeffrey Dixon; Rongguo Yu; Nattapon Panupinthu; John X Wilson
Activation of P2 nucleotide receptors stimulates acid efflux from astrocytes.
Glia 2004;47(4):367-76.
2004: Nestor A Bayona; Adrian W Gelb; Zongbin Jiang; John X Wilson; Bradley L Urquhart; David F Cechetto
Propofol neuroprotection in cerebral ischemia and its effects on low-molecular-weight antioxidants and skilled motor tasks.
Anesthesiology 2004;100(5):1151-9.
2004: Tom Chan; John X Wilson; Peter J O'Brien
Glycogenolysis is directed towards ascorbate synthesis by glutathione conjugation.
Biochemical and biophysical research communications 2004;317(1):149-56.
2004: Tom Chan; John X Wilson; Peter J O'Brien
Coenzyme Q cytoprotective mechanisms.
Methods in enzymology 2004;382():89-104.
2003: Jasminka Korcok; S Jeffrey Dixon; Theodore C Y Lo; John X Wilson
Differential effects of glucose on dehydroascorbic acid transport and intracellular ascorbate accumulation in astrocytes and skeletal myocytes.
Brain research 2003;993(1-2):201-7.
2003: Feng Wu; John X Wilson; Karel Tyml
Ascorbate inhibits iNOS expression and preserves vasoconstrictor responsiveness in skeletal muscle of septic mice.
American journal of physiology. Regulatory, integrative and comparative physiology 2003;285(1):R50-6.
2003: John X Wilson; G Bryan Young
Progress in clinical neurosciences: sepsis-associated encephalopathy: evolving concepts.
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 2003;30(2):98-105.
2002: John X Wilson
The physiological role of dehydroascorbic acid.
FEBS letters 2002;527(1-3):5-9.
2002: Giuseppe Galati; Omid Sabzevari; John X Wilson; Peter J O'Brien
Prooxidant activity and cellular effects of the phenoxyl radicals of dietary flavonoids and other polyphenolics.
Toxicology 2002;177(1):91-104.
2002: Rina Daskalopoulos; Jasminka Korcok; Lei Tao; John X Wilson
Accumulation of intracellular ascorbate from dehydroascorbic acid by astrocytes is decreased after oxidative stress and restored by propofol.
Glia 2002;39(2):124-32.
2002: Feng Wu; Karel Tyml; John X Wilson
Ascorbate inhibits iNOS expression in endotoxin- and IFN gamma-stimulated rat skeletal muscle endothelial cells.
FEBS letters 2002;520(1-3):122-6.
2002: Adrian W Gelb; Nestor A Bayona; John X Wilson; David F Cechetto
Propofol anesthesia compared to awake reduces infarct size in rats.
Anesthesiology 2002;96(5):1183-90.
2002: Tom Chan; Shirley Teng; John X Wilson; Giuseppe Galati; Sumsallah Khan; Peter J O'Brien
Coenzyme Q cytoprotective mechanisms for mitochondrial complex I cytopathies involves NAD(P)H: quinone oxidoreductase 1(NQO1).
Free radical research 2002;36(4):421-7.
2002: Jasminka Korcok; Feng Wu; Karel Tyml; Robert R Hammond; John X Wilson
Sepsis inhibits reduction of dehydroascorbic acid and accumulation of ascorbate in astroglial cultures: intracellular ascorbate depletion increases nitric oxide synthase induction and glutamate uptake inhibition.
Journal of neurochemistry 2002;81(1):185-93.
2002: Melanie E Holmes; James Mwanjewe; Sue E Samson; James V Haist; John X Wilson; S Jeffrey Dixon; Morris Karmazyn; Ashok K Grover
Dehydroascorbic acid uptake by coronary artery smooth muscle: effect of intracellular acidification.
The Biochemical journal 2002;362(Pt 2):507-12.
2002: John X Wilson; Adrian W Gelb
Free radicals, antioxidants, and neurologic injury: possible relationship to cerebral protection by anesthetics.
Journal of neurosurgical anesthesiology 2002;14(1):66-79.
2001: F Wu; Gediminas Cepinskas; John X Wilson; Karel Tyml
Nitric oxide attenuates but superoxide enhances iNOS expression in endotoxin- and IFNgamma-stimulated skeletal muscle endothelial cells.
Microcirculation (New York, N.Y. : 1994) 2001;8(6):415-25.
2001: R Daskalopoulos; Jasminka Korcok; P Farhangkhgoee; Morris Karmazyn; Adrian W Gelb; John X Wilson
Propofol protection of sodium-hydrogen exchange activity sustains glutamate uptake during oxidative stress.
Anesthesia and analgesia 2001;93(5):1199-204.
2001: Adrian W Gelb; John X Wilson; David F Cechetto
Anesthetics and cerebral ischemia--should we continue to dream the impossible dream?
Canadian journal of anaesthesia = Journal canadien d'anesthésie 2001;48(8):727-31.
2001: J Armour; Karel Tyml; Darcy Lidington; John X Wilson
Ascorbate prevents microvascular dysfunction in the skeletal muscle of the septic rat.
Journal of applied physiology (Bethesda, Md. : 1985) 2001;90(3):795-803.
2001: C E Peters; Jasminka Korcok; Adrian W Gelb; John X Wilson
Anesthetic concentrations of propofol protect against oxidative stress in primary astrocyte cultures: comparison with hypothermia.
Anesthesiology 2001;94(2):313-21.
2000: Jasminka Korcok; R Yan; Ramin Siushansian; S Jeffrey Dixon; John X Wilson
Sodium-ascorbate cotransport controls intracellular ascorbate concentration in primary astrocyte cultures expressing the SVCT2 transporter.
Brain research 2000;881(2):144-51.
2000: Melanie E Holmes; Sue E Samson; John X Wilson; S Jeffrey Dixon; Ashok K Grover
Ascorbate transport in pig coronary artery smooth muscle: Na(+) removal and oxidative stress increase loss of accumulated cellular ascorbate.
Journal of vascular research 2000;37(5):390-8.
2000: John X Wilson; C E Peters; S M Sitar; P Daoust; Adrian W Gelb
Glutamate stimulates ascorbate transport by astrocytes.
Brain research 2000;858(1):61-6.
1999: Milos Pekny; Camilla Eliasson; Ramin Siushansian; M Ding; S Jeffrey Dixon; Marcela Pekna; John X Wilson; Anders Hamberger
The impact of genetic removal of GFAP and/or vimentin on glutamine levels and transport of glucose and ascorbate in astrocytes.
Neurochemical research 1999;24(11):1357-62.
1999: S M Sitar; Payman Hanifi Moghaddam; A Gelb; David F Cechetto; Ramin Siushansian; John X Wilson
Propofol prevents peroxide-induced inhibition of glutamate transport in cultured astrocytes.
Anesthesiology 1999;90(5):1446-53.
1998: mark ozog; John X Wilson; S Jeffrey Dixon; David F Cechetto
Rilmenidine elevates cytosolic free calcium concentration in suspended cerebral astrocytes.
Journal of neurochemistry 1998;71(4):1429-35.
1998: S Qutob; S Jeffrey Dixon; John X Wilson
Insulin stimulates vitamin C recycling and ascorbate accumulation in osteoblastic cells.
Endocrinology 1998;139(1):51-6.
1997: John X Wilson
Antioxidant defense of the brain: a role for astrocytes.
Canadian journal of physiology and pharmacology 1997;75(10-11):1149-63.
1997: Ramin Siushansian; L Tao; S Jeffrey Dixon; John X Wilson
Cerebral astrocytes transport ascorbic acid and dehydroascorbic acid through distinct mechanisms regulated by cyclic AMP.
Journal of neurochemistry 1997;68(6):2378-85.
1996: John X Wilson; S Jeffrey Dixon; J Yu; S Nees; Karel Tyml
Ascorbate uptake by microvascular endothelial cells of rat skeletal muscle.
Microcirculation (New York, N.Y. : 1994) 1996;3(2):211-21.
1996: Ramin Siushansian; S Jeffrey Dixon; John X Wilson
Osmotic swelling stimulates ascorbate efflux from cerebral astrocytes.
Journal of neurochemistry 1996;66(3):1227-33.
1995: Ramin Siushansian; John X Wilson
Ascorbate transport and intracellular concentration in cerebral astrocytes.
Journal of neurochemistry 1995;65(1):41-9.
1995: Renny Franceschi; John X Wilson; S Jeffrey Dixon
Requirement for Na(+)-dependent ascorbic acid transport in osteoblast function.
The American journal of physiology 1995;268(6 Pt 1):C1430-9.
1995: John X Wilson; S Jeffrey Dixon
Ascorbate concentration in osteoblastic cells is elevated by transforming growth factor-beta.
The American journal of physiology 1995;268(4 Pt 1):E565-71.
1993: K S Butcher; vladimir hachinski; John X Wilson; Colette Guiraudon; David F Cechetto
Cardiac and sympathetic effects of middle cerebral artery occlusion in the spontaneously hypertensive rat.
Brain research 1993;621(1):79-86.
1992: vladimir hachinski; S M Oppenheimer; John X Wilson; Colette Guiraudon; David F Cechetto
Asymmetry of sympathetic consequences of experimental stroke.
Archives of neurology 1992;49(7):697-702.
1992: vladimir hachinski; John X Wilson; K E Smith; David F Cechetto
Effect of age on autonomic and cardiac responses in a rat stroke model.
Archives of neurology 1992;49(7):690-6.
1992: John X Wilson; Ewa Jaworski
Effect of oxygen on ascorbic acid uptake and concentration in embryonic chick brain.
Neurochemical research 1992;17(6):571-6.
1992: S Jeffrey Dixon; John X Wilson
Adaptive regulation of ascorbate transport in osteoblastic cells.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1992;7(6):675-81.
1992: S M Oppenheimer; T M Saleh; John X Wilson; David F Cechetto
Plasma and organ catecholamine levels following stimulation of the rat insular cortex.
Brain research 1992;569(2):221-8.
1992: S Jeffrey Dixon; John X Wilson
Transforming growth factor-beta stimulates ascorbate transport activity in osteoblastic cells.
Endocrinology 1992;130(1):484-9.
1991: John X Wilson; G A Wilson
Accumulation of noradrenaline and its oxidation products by cultured rodent astrocytes.
Neurochemical research 1991;16(11):1199-205.
1991: S Jeffrey Dixon; A Kulaga; Ewa Jaworski; John X Wilson
Ascorbate uptake by ROS 17/2.8 osteoblast-like cells: substrate specificity and sensitivity to transport inhibitors.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1991;6(6):623-9.
1991: S M Oppenheimer; John X Wilson; Colette Guiraudon; David F Cechetto
Insular cortex stimulation produces lethal cardiac arrhythmias: a mechanism of sudden death?
Brain research 1991;550(1):115-21.
1991: John X Wilson; Ewa Jaworski; S Jeffrey Dixon
Evidence for electrogenic sodium-dependent ascorbate transport in rat astroglia.
Neurochemical research 1991;16(1):73-8.
1990: John X Wilson; Ewa Jaworski; A Kulaga; S Jeffrey Dixon
Substrate regulation of ascorbate transport activity in astrocytes.
Neurochemical research 1990;15(10):1037-43.
1989: John X Wilson; S Jeffrey Dixon
Ascorbic acid transport in mouse and rat astrocytes is reversibly inhibited by furosemide, SITS, and DIDS.
Neurochemical research 1989;14(12):1169-75.
1989: David F Cechetto; John X Wilson; K E Smith; D Wolski; M D Silver; vladimir hachinski
Autonomic and myocardial changes in middle cerebral artery occlusion: stroke models in the rat.
Brain research 1989;502(2):296-305.
1989: John X Wilson; S Jeffrey Dixon
High-affinity sodium-dependent uptake of ascorbic acid by rat osteoblasts.
The Journal of membrane biology 1989;111(1):83-91.
1989: John X Wilson
Ascorbic acid uptake by a high-affinity sodium-dependent mechanism in cultured rat astrocytes.
Journal of neurochemistry 1989;53(4):1064-71.