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Mark Wilson

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Chemicals & Drugs

Procedures

Enzyme-Linked Immunosorbent Assay

Physiology

Protein Folding

Phenomena

Living Beings

Cattle
Mice

Concepts & Ideas

Anatomy

Mitochondria

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Network (preview)

Co-Publications
Name
16
Easterbrook-Smith, Simon
10
Yerbury, Justin
8
Poon, Stephen
7
Carver, John
5
Dobson, Christopher
4
Humphreys, DT
3
Hochgrebe, Tim
3
Rybchyn, Mark
3
Stewart, Elise
3
Jones, Rachel
3
Kumita, Janet
3
Meehan, Sarah
2
Thorn, David
2
Rekas, Agata
2
Walker, Mark

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Publications

TOP 3
Wyatt Amy R; Yerbury Justin J; Wilson Mark R
Structural characterization of clusterin-chaperone client protein complexes.
Yerbury Justin J; Kumita Janet R; Meehan Sarah; Dobson Christopher M; Wilson Mark R
alpha2-Macroglobulin and haptoglobin suppress amyloid formation by interacting with prefibrillar protein species.
Wyatt A R; Yerbury J J; Poon S; Wilson M R
Therapeutic targets in extracellular protein deposition diseases.

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All Publications

2009: Wyatt Amy R; Yerbury Justin J; Wilson Mark R
Structural characterization of clusterin-chaperone client protein complexes.
The Journal of biological chemistry 2009;284(33):21920-7.
2009: Yerbury Justin J; Kumita Janet R; Meehan Sarah; Dobson Christopher M; Wilson Mark R
alpha2-Macroglobulin and haptoglobin suppress amyloid formation by interacting with prefibrillar protein species.
The Journal of biological chemistry 2009;284(7):4246-54.
2009: Wyatt A R; Yerbury J J; Poon S; Wilson M R
Therapeutic targets in extracellular protein deposition diseases.
Current medicinal chemistry 2009;16(22):2855-66.
2008: Park Dong Choon; Yeo Seung Geun; Wilson Mark R; Yerbury Justin J; Kwong Joseph; Welch William R; Choi Yang Kyu; Birrer Michael J; Mok Samuel C; Wong Kwong-Kwok
Clusterin interacts with Paclitaxel and confer Paclitaxel resistance in ovarian cancer.
Neoplasia (New York, N.Y.) 2008;10(9):964-72.
2008: Gillen Christine M; Courtney Harry S; Schulze Kai; Rohde Manfred; Wilson Mark R; Timmer Anjuli M; Guzman Carlos A; Nizet Victor; Chhatwal G S; Walker Mark J
Opacity factor activity and epithelial cell binding by the serum opacity factor protein of Streptococcus pyogenes are functionally discrete.
The Journal of biological chemistry 2008;283(10):6359-66.
2008: French Katie; Yerbury Justin J; Wilson Mark R
Protease activation of alpha2-macroglobulin modulates a chaperone-like action with broad specificity.
Biochemistry 2008;47(4):1176-85.
2008: Wilson Mark R; Yerbury Justin J; Poon Stephen
Potential roles of abundant extracellular chaperones in the control of amyloid formation and toxicity.
Molecular bioSystems 2008;4(1):42-52.
2007: Yerbury Justin J; Poon Stephen; Meehan Sarah; Thompson Brianna; Kumita Janet R; Dobson Christopher M; Wilson Mark R
The extracellular chaperone clusterin influences amyloid formation and toxicity by interacting with prefibrillar structures.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007;21(10):2312-22.
2007: Kumita Janet R; Poon Stephen; Caddy Gemma L; Hagan Christine L; Dumoulin Mireille; Yerbury Justin J; Stewart Elise M; Robinson Carol V; Wilson Mark R; Dobson Christopher M
The extracellular chaperone clusterin potently inhibits human lysozyme amyloid formation by interacting with prefibrillar species.
Journal of molecular biology 2007;369(1):157-67.
2007: Stewart Elise M; Aquilina J Andrew; Easterbrook-Smith Simon B; Murphy-Durland Danielle; Jacobsen Christian; Moestrup Soren; Wilson Mark R
Effects of glycosylation on the structure and function of the extracellular chaperone clusterin.
Biochemistry 2007;46(5):1412-22.
2005: Thorn David C; Meehan Sarah; Sunde Margaret; Rekas Agata; Gras Sally L; MacPhee Cait E; Dobson Christopher M; Wilson Mark R; Carver John A
Amyloid fibril formation by bovine milk kappa-casein and its inhibition by the molecular chaperones alphaS- and beta-casein.
Biochemistry 2005;44(51):17027-36.
2005: Yerbury Justin J; Stewart Elise M; Wyatt Amy R; Wilson Mark R
Quality control of protein folding in extracellular space.
EMBO reports 2005;6(12):1131-6.
2005: Yerbury Justin J; Rybchyn Mark S; Easterbrook-Smith Simon B; Henriques Cindy; Wilson Mark R
The acute phase protein haptoglobin is a mammalian extracellular chaperone with an action similar to clusterin.
Biochemistry 2005;44(32):10914-25.
2005: Dedmon Matthew M; Christodoulou John; Wilson Mark R; Dobson Christopher M
Heat shock protein 70 inhibits alpha-synuclein fibril formation via preferential binding to prefibrillar species.
The Journal of biological chemistry 2005;280(15):14733-40.
2004: Jones Rachel A; Poniris Maree H; Wilson Mark R
pDMAEMA is internalised by endocytosis but does not physically disrupt endosomes.
Journal of controlled release : official journal of the Controlled Release Society 2004;96(3):379-91.
2003: Carver John A; Rekas Agata; Thorn David C; Wilson Mark R
Small heat-shock proteins and clusterin: intra- and extracellular molecular chaperones with a common mechanism of action and function?
IUBMB life 2003;55(12):661-8.
2003: Jones Rachel A; Cheung Charles Y; Black Fiona E; Zia Jasmine K; Stayton Patrick S; Hoffman Allan S; Wilson Mark R
Poly(2-alkylacrylic acid) polymers deliver molecules to the cytosol by pH-sensitive disruption of endosomal vesicles.
The Biochemical journal 2003;372(Pt 1):65-75.
2002: Poon Stephen; Rybchyn Mark S; Easterbrook-Smith Simon B; Carver John A; Pankhurst Greg J; Wilson Mark R
Mildly acidic pH activates the extracellular molecular chaperone clusterin.
The Journal of biological chemistry 2002;277(42):39532-40.
2002: Jones Rachel A; Smail Alison; Wilson Mark R
Detecting mitochondrial permeability transition by confocal imaging of intact cells pinocytically loaded with calcein.
European journal of biochemistry / FEBS 2002;269(16):3990-7.
2002: Hatters Danny M; Wilson Mark R; Easterbrook-Smith Simon B; Howlett Geoffrey J
Suppression of apolipoprotein C-II amyloid formation by the extracellular chaperone, clusterin.
European journal of biochemistry / FEBS 2002;269(11):2789-94.
2002: Poon Stephen; Treweek Teresa M; Wilson Mark R; Easterbrook-Smith Simon B; Carver John A
Clusterin is an extracellular chaperone that specifically interacts with slowly aggregating proteins on their off-folding pathway.
FEBS letters 2002;513(2-3):259-66.
2002: Lakins Johnathon N; Poon Stephen; Easterbrook-Smith Simon B; Carver John A; Tenniswood Martin P R; Wilson Mark R
Evidence that clusterin has discrete chaperone and ligand binding sites.
Biochemistry 2002;41(1):282-91.
2001: Gilmore K J; Quinn H E; Wilson M R
Pinocytic loading of cytochrome c into intact cells specifically induces caspase-dependent permeabilization of mitochondria: evidence for a cytochrome c feedback loop.
Cell death and differentiation 2001;8(6):631-9.
2000: Poon S; Easterbrook-Smith S B; Rybchyn M S; Carver J A; Wilson M R
Clusterin is an ATP-independent chaperone with very broad substrate specificity that stabilizes stressed proteins in a folding-competent state.
Biochemistry 2000;39(51):15953-60.
2000: Wilson M R; Easterbrook-Smith S B
Clusterin is a secreted mammalian chaperone.
Trends in biochemical sciences 2000;25(3):95-8.
1999: Humphreys D T; Wilson M R
Modes of L929 cell death induced by TNF-alpha and other cytotoxic agents.
Cytokine 1999;11(10):773-82.
1999: Hochgrebe T T; Humphreys D; Wilson M R; Easterbrook-Smith S B
A reexamination of the role of clusterin as a complement regulator.
Experimental cell research 1999;249(1):13-21.
1999: Humphreys D T; Carver J A; Easterbrook-Smith S B; Wilson M R
Clusterin has chaperone-like activity similar to that of small heat shock proteins.
The Journal of biological chemistry 1999;274(11):6875-81.
1998: Wilson M R
Apoptosis: unmasking the executioner.
Cell death and differentiation 1998;5(8):646-52.
1998: Gelissen I C; Hochgrebe T; Wilson M R; Easterbrook-Smith S B; Jessup W; Dean R T; Brown A J
Apolipoprotein J (clusterin) induces cholesterol export from macrophage-foam cells: a potential anti-atherogenic function?
The Biochemical journal 1998;331 ( Pt 1)():231-7.
1997: Humphreys D; Hochgrebe T T; Easterbrook-Smith S B; Tenniswood M P; Wilson M R
Effects of clusterin overexpression on TNFalpha- and TGFbeta-mediated death of L929 cells.
Biochemistry 1997;36(49):15233-43.
1996: Partridge S R; Baker M S; Walker M J; Wilson M R
Clusterin, a putative complement regulator, binds to the cell surface of Staphylococcus aureus clinical isolates.
Infection and immunity 1996;64(10):4324-9.
1993: Wilson M R; Easterbrook-Smith S B
Enzyme complex amplification--a signal amplification method for use in enzyme immunoassays.
Analytical biochemistry 1993;209(1):183-7.
1992: Wilson M R; Easterbrook-Smith S B
Clusterin binds by a multivalent mechanism to the Fc and Fab regions of IgG.
Biochimica et biophysica acta 1992;1159(3):319-26.
1992: Easterbrook-Smith S B; Wilson M R; Wines B D
RHP is antigenically related to factor H and binds to the globular heads of C1q.
Molecular immunology 1992;29(10):1203-7.
1991: Wilson M R; Roeth P J; Easterbrook-Smith S B
Clusterin enhances the formation of insoluble immune complexes.
Biochemical and biophysical research communications 1991;177(3):985-90.

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