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Patricia Wilson

Research Profile

Disorders

Polycystic Kidney, Autosomal Dominant

Anatomy

Chemicals & Drugs

Concepts & Ideas

Phenomena

Blotting, Western

Co-author Network

Publications

TOP 3
Xiaohong Li; Deborah P Hyink; Brian Radbill; Marius Sudol; Haojiang Zhang; Nadezda N Zheleznova; Patricia D Wilson
Protein kinase-X interacts with Pin-1 and Polycystin-1 during mouse kidney development.
Beatrice Goilav; Lisa M Satlin; Patricia D Wilson
Pathways of apoptosis in human autosomal recessive and autosomal dominant polycystic kidney diseases.
Rajeev Rohatgi; Lorenzo Battini; Paul Kim; Sharon Israeli; Patricia D Wilson; G Luca Gusella; Lisa M Satlin
Mechanoregulation of intracellular Ca2+ in human autosomal recessive polycystic kidney disease cyst-lining renal epithelial cells.

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All Publications

2009: Xiaohong Li; Deborah P Hyink; Brian Radbill; Marius Sudol; Haojiang Zhang; Nadezda N Zheleznova; Patricia D Wilson
Protein kinase-X interacts with Pin-1 and Polycystin-1 during mouse kidney development.
Kidney international 2009;76(1):54-62.
2008: Beatrice Goilav; Lisa M Satlin; Patricia D Wilson
Pathways of apoptosis in human autosomal recessive and autosomal dominant polycystic kidney diseases.
Pediatric nephrology (Berlin, Germany) 2008;23(9):1473-82.
2008: Rajeev Rohatgi; Lorenzo Battini; Paul Kim; Sharon Israeli; Patricia D Wilson; G Luca Gusella; Lisa M Satlin
Mechanoregulation of intracellular Ca2+ in human autosomal recessive polycystic kidney disease cyst-lining renal epithelial cells.
American journal of physiology. Renal physiology 2008;294(4):F890-9.
2008: Xiaohong Li; Christopher R Burrow; Katalin Polgar; Deborah P Hyink; G Luca Gusella; Patricia D Wilson
Protein kinase X (PRKX) can rescue the effects of polycystic kidney disease-1 gene (PKD1) deficiency.
Biochimica et biophysica acta 2008;1782(1):1-9.
2007: Patricia D Wilson; Beatrice Goilav
Cystic disease of the kidney.
Annual review of pathology 2007;2():341-68.
2006: M Albert Basson; Judy Watson-Johnson; Reena Shakya; Simge Akbulut; Deborah P Hyink; Frank Costantini; Patricia D Wilson; Ivor Mason; Jonathan D Licht
Branching morphogenesis of the ureteric epithelium during kidney development is coordinated by the opposing functions of GDNF and Sprouty1.
Developmental biology 2006;299(2):466-77.
2006: Lorenzo Battini; Elena Fedorova; Salvador Macip; Xiaohong Li; Patricia D Wilson; G Luca Gusella
Stable knockdown of polycystin-1 confers integrin-alpha2beta1-mediated anoikis resistance.
Journal of the American Society of Nephrology : JASN 2006;17(11):3049-58.
2006: Samantha J Wilson; Kurt Amsler; Deborah P Hyink; Xiaohong Li; Weining Lu; Jing Zhou; Christopher R Burrow; Patricia D Wilson
Inhibition of HER-2(neu/ErbB2) restores normal function and structure to polycystic kidney disease (PKD) epithelia.
Biochimica et biophysica acta 2006;1762(7):647-55.
2006: Cécile Vigneau; Feng Zheng; Katalin Polgar; Patricia D Wilson; Gary E Striker
Stem cells and kidney injury.
Current opinion in nephrology and hypertension 2006;15(3):238-44.
2006: Michael J Ross; Matthew Wosnitzer; Michael D Ross; Benedetta Granelli; G Luca Gusella; Mohammad Husain; Lewis Kaufman; Matthew Vasievich; Vivette D D'Agati; Patricia D Wilson; Mary E Klotman; Paul E Klotman
Role of ubiquitin-like protein FAT10 in epithelial apoptosis in renal disease.
Journal of the American Society of Nephrology : JASN 2006;17(4):996-1004.
2005: Xiaohong Li; Deborah P Hyink; Katalin Polgar; G Luca Gusella; Patricia D Wilson; Christopher R Burrow
Protein kinase X activates ureteric bud branching morphogenesis in developing mouse metanephric kidney.
Journal of the American Society of Nephrology : JASN 2005;16(12):3543-52.
2005: Katalin Polgar; Christopher R Burrow; Deborah P Hyink; Hilda Fernandez; Katie Thornton; Xiaohong Li; G Luca Gusella; Patricia D Wilson
Disruption of polycystin-1 function interferes with branching morphogenesis of the ureteric bud in developing mouse kidneys.
Developmental biology 2005;286(1):16-30.
2005: M Albert Basson; Simge Akbulut; Judy Watson-Johnson; Ruth Simon; Thomas J. Carroll; Reena Shakya; Isabelle Gross; Gail R Martin; Thomas Lufkin; Andrew P McMahon; Patricia D Wilson; Frank Costantini; Ivor Mason; Jonathan D Licht
Sprouty1 is a critical regulator of GDNF/RET-mediated kidney induction.
Developmental cell 2005;8(2):229-39.
2004: Patricia D Wilson
Polycystic kidney disease: new understanding in the pathogenesis.
The international journal of biochemistry & cell biology 2004;36(10):1868-73.
2004: Libo Qiu; Deborah P Hyink; William H Gans; Kurt Amsler; Patricia D Wilson; Christopher R Burrow
Midkine promotes selective expansion of the nephrogenic mesenchyme during kidney organogenesis.
Organogenesis 2004;1(1):14-21.
2004: Patricia D Wilson
Polycystic kidney disease.
The New England journal of medicine 2004;350(2):151-64.
2003: Isabelle Gross; Debra J Morrison; Deborah P Hyink; Kylie Georgas; Milton A English; Mathias Mericskay; Seiyu Hosono; David Sassoon; Patricia D Wilson; Melissa Little; Jonathan D Licht
The receptor tyrosine kinase regulator Sprouty1 is a target of the tumor suppressor WT1 and important for kidney development.
The Journal of biological chemistry 2003;278(42):41420-30.
2003: Rajeev Rohatgi; Andrew Greenberg; Christopher R Burrow; Patricia D Wilson; Lisa M Satlin
Na transport in autosomal recessive polycystic kidney disease (ARPKD) cyst lining epithelial cells.
Journal of the American Society of Nephrology : JASN 2003;14(4):827-36.
2002: Patricia D Wilson
The genes and proteins associated with poly-cystic kidney diseases.
Minerva urologica e nefrologica = The Italian journal of urology and nephrology 2002;54(4):201-11.
2002: Xiaohong Li; Hsi-Ping Li; Kurt Amsler; Deborah P Hyink; Patricia D Wilson; Christopher R Burrow
PRKX, a phylogenetically and functionally distinct cAMP-dependent protein kinase, activates renal epithelial cell migration and morphogenesis.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(14):9260-5.
2002: Aaron S Stern; Mary E Klotman; Yiannis A Ioannou; Christopher R Burrow; Patricia D Wilson; Paul E Klotman; Michael Lipkowitz
Polarity of alpha-galactosidase A uptake by renal tubule cells.
Kidney international 2002;61(1 Suppl):S52-5.
2001: Michael J Ross; Leslie A Bruggeman; Patricia D Wilson; Paul E Klotman
Microcyst formation and HIV-1 gene expression occur in multiple nephron segments in HIV-associated nephropathy.
Journal of the American Society of Nephrology : JASN 2001;12(12):2645-51.
2001: Deborah P Hyink; JZ Rappoport; Patricia D Wilson; Ruth G Abramson
Expression of the urate transporter/channel is developmentally regulated in human kidneys.
American journal of physiology. Renal physiology 2001;281(5):F875-86.
2000: Lin Geng; Christopher R Burrow; Hsi-Ping Li; Patricia D Wilson
Modification of the composition of polycystin-1 multiprotein complexes by calcium and tyrosine phosphorylation.
Biochimica et biophysica acta 2000;1535(1):21-35.
2000: L Qiu; C R Escalante; Aneel K Aggarwal; Patricia D Wilson; Christopher R Burrow
Monomeric midkine induces tumor cell proliferation in the absence of cell-surface proteoglycan binding.
Biochemistry 2000;39(20):5977-87.
2000: Jerome M Lasker; W B Chen; I Wolf; B P Bloswick; Patricia D Wilson; P K Powell
Formation of 20-hydroxyeicosatetraenoic acid, a vasoactive and natriuretic eicosanoid, in human kidney. Role of Cyp4F2 and Cyp4A11.
The Journal of biological chemistry 2000;275(6):4118-26.
2000: Patricia D Wilson; O Devuyst; Xiaohong Li; L Gatti; D Falkenstein; S Robinson; D Fambrough; Christopher R Burrow
Apical plasma membrane mispolarization of NaK-ATPase in polycystic kidney disease epithelia is associated with aberrant expression of the beta2 isoform.
The American journal of pathology 2000;156(1):253-68.
1999: Patricia D Wilson; Lin Geng; Xiaohong Li; Christopher R Burrow
The PKD1 gene product, "polycystin-1," is a tyrosine-phosphorylated protein that colocalizes with alpha2beta1-integrin in focal clusters in adherent renal epithelia.
Laboratory investigation; a journal of technical methods and pathology 1999;79(10):1311-23.
1999: Christopher R Burrow; O Devuyst; Xiaohong Li; L Gatti; Patricia D Wilson
Expression of the beta2-subunit and apical localization of Na+-K+-ATPase in metanephric kidney.
The American journal of physiology 1999;277(3 Pt 2):F391-403.
1999: Michael Lipkowitz; Basil Hanss; N Tulchin; Patricia D Wilson; J C Langer; Michael D Ross; G J Kurtzman; Paul E Klotman; Mary E Klotman
Transduction of renal cells in vitro and in vivo by adeno-associated virus gene therapy vectors.
Journal of the American Society of Nephrology : JASN 1999;10(9):1908-15.
1999: Hsi-Ping Li; Lin Geng; Christopher R Burrow; Patricia D Wilson
Identification of phosphorylation sites in the PKD1-encoded protein C-terminal domain.
Biochemical and biophysical research communications 1999;259(2):356-63.
1999: Patricia D Wilson; Lisa M Guay-Woodford
Pathophysiology and clinical management of polycystic kidney disease in women.
Seminars in nephrology 1999;19(2):123-32.
1999: Patricia D Wilson; J S Hovater; C C Casey; J A Fortenberry; Erik M Schwiebert
ATP release mechanisms in primary cultures of epithelia derived from the cysts of polycystic kidneys.
Journal of the American Society of Nephrology : JASN 1999;10(2):218-29.
1999: Seiyu Hosono; X Luo; Deborah P Hyink; Lynn M Schnapp; Patricia D Wilson; Christopher R Burrow; J C Reddy; George F Atweh; Jonathan D Licht
WT1 expression induces features of renal epithelial differentiation in mesenchymal fibroblasts.
Oncogene 1999;18(2):417-27.
1997: Patricia D Wilson
Epithelial cell polarity and disease.
The American journal of physiology 1997;272(4 Pt 2):F434-42.
1997: P A Hartz; Patricia D Wilson
Functional defects in lysosomal enzymes in autosomal dominant polycystic kidney disease (ADPKD): abnormalities in synthesis, molecular processing, polarity, and secretion.
Biochemical and molecular medicine 1997;60(1):8-26.
1996: O Devuyst; Christopher R Burrow; Erik M Schwiebert; William B Guggino; Patricia D Wilson
Developmental regulation of CFTR expression during human nephrogenesis.
The American journal of physiology 1996;271(3 Pt 2):F723-35.
1996: O Devuyst; Christopher R Burrow; B L Smith; Peter Agre; M A Knepper; Patricia D Wilson
Expression of aquaporins-1 and -2 during nephrogenesis and in autosomal dominant polycystic kidney disease.
The American journal of physiology 1996;271(1 Pt 2):F169-83.
1996: Marcelo Marcos Morales; T P Carroll; T Morita; Erik M Schwiebert; O Devuyst; Patricia D Wilson; Aníbal G Lopes; Bruce A Stanton; Harry C Dietz; Garry R Cutting; William B Guggino
Both the wild type and a functional isoform of CFTR are expressed in kidney.
The American journal of physiology 1996;270(6 Pt 2):F1038-48.
1996: Willemijntje A Hoogerwerf; S C Tsao; O Devuyst; S A Levine; C H Chris Yun; J W Yip; M E Cohen; Patricia D Wilson; Audrey Lazenby; Chung-Ming Tse; Mark Donowitz
NHE2 and NHE3 are human and rabbit intestinal brush-border proteins.
The American journal of physiology 1996;270(1 Pt 1):G29-41.
1996: K Hanaoka; O Devuyst; Erik M Schwiebert; Patricia D Wilson; William B Guggino
A role for CFTR in human autosomal dominant polycystic kidney disease.
The American journal of physiology 1996;270(1 Pt 1):C389-99.
1995: Lorraine C Racusen; Patricia D Wilson; P A Hartz; Barbara A Fivush; Christopher R Burrow
Renal proximal tubular epithelium from patients with nephropathic cystinosis: immortalized cell lines as in vitro model systems.
Kidney international 1995;48(2):536-43.
1995: Patricia D Wilson; D Falkenstein
The pathology of human renal cystic disease.
Current topics in pathology. Ergebnisse der Pathologie 1995;88():1-50.
1993: Christopher R Burrow; Patricia D Wilson
A putative Wilms tumor-secreted growth factor activity required for primary culture of human nephroblasts.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(13):6066-70.
1993: Patricia D Wilson; Jing Du; J T Norman
Autocrine, endocrine and paracrine regulation of growth abnormalities in autosomal dominant polycystic kidney disease.
European journal of cell biology 1993;61(1):131-8.