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Timothy Wilson

Research Profile

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Publications

TOP 3
Stephanie Kath-Schorr; Nan-Sheng Li; Jun Lu; Joseph A Piccirilli; Timothy J Wilson; David M J Lilley
General acid-base catalysis mediated by nucleobases in the hairpin ribozyme.
Jonathan Ouellet; Stephanie Schorr; Timothy J Wilson; Asif Iqbal; David M J Lilley
Orientation of cyanine fluorophores terminally attached to DNA via long, flexible tethers.
Nan-Sheng Li; John K Frederiksen; Selene C Koo; Jun Lu; Timothy J Wilson; David M J Lilley; Joseph A Piccirilli
A general and efficient approach for the construction of RNA oligonucleotides containing a 5'-phosphorothiolate linkage.

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All Publications

2012: Stephanie Kath-Schorr; Nan-Sheng Li; Jun Lu; Joseph A Piccirilli; Timothy J Wilson; David M J Lilley
General acid-base catalysis mediated by nucleobases in the hairpin ribozyme.
Journal of the American Chemical Society 2012;134(40):16717-24.
2011: Jonathan Ouellet; Stephanie Schorr; Timothy J Wilson; Asif Iqbal; David M J Lilley
Orientation of cyanine fluorophores terminally attached to DNA via long, flexible tethers.
Biophysical journal 2011;101(5):1148-54.
2011: Nan-Sheng Li; John K Frederiksen; Selene C Koo; Jun Lu; Timothy J Wilson; David M J Lilley; Joseph A Piccirilli
A general and efficient approach for the construction of RNA oligonucleotides containing a 5'-phosphorothiolate linkage.
Nucleic acids research 2011;39(5):e31.
2011: Timothy J Wilson; David M J Lilley
Do the hairpin and VS ribozymes share a common catalytic mechanism based on general acid-base catalysis? A critical assessment of available experimental data.
RNA (New York, N.Y.) 2011;17(2):213-21.
2010: Timothy J Wilson; Nan-Sheng Li; Jun Lu; John K Frederiksen; Joseph A Piccirilli; David M J Lilley
Nucleobase-mediated general acid-base catalysis in the Varkud satellite ribozyme.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(26):11751-6.
2009: Lisa Araki; Keiji Morita; Maho Yamaguchi; Zheng-Yun Zhao; Timothy J Wilson; David M J Lilley; Shinya Harusawa
Synthesis of novel C4-linked C2-imidazole ribonucleoside phosphoramidite and its application to probing the catalytic mechanism of a ribozyme.
The Journal of organic chemistry 2009;74(6):2350-6.
2009: Timothy J Wilson; David M J Lilley
Biochemistry. The evolution of ribozyme chemistry.
Science (New York, N.Y.) 2009;323(5920):1436-8.
2008: Asif Iqbal; Sinan Arslan; Burak Okumus; Timothy J Wilson; Gerard Giraud; David G Norman; Taekjip Ha; David M J Lilley
Orientation dependence in fluorescent energy transfer between Cy3 and Cy5 terminally attached to double-stranded nucleic acids.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(32):11176-81.
2007: Timothy J Wilson; Aileen C McLeod; David M J Lilley
A guanine nucleobase important for catalysis by the VS ribozyme.
The EMBO journal 2007;26(10):2489-500.
2007: Timothy J Wilson; Michelle K Nahas; Lisa Araki; Shinya Harusawa; Taekjip Ha; David M J Lilley
RNA folding and the origins of catalytic activity in the hairpin ribozyme.
Blood cells, molecules & diseases 2007;38(1):8-14.
2006: Timothy J Wilson; Jonathan Ouellet; Zheng-Yun Zhao; Shinya Harusawa; Lisa Araki; Takushi Kurihara; David M J Lilley
Nucleobase catalysis in the hairpin ribozyme.
RNA (New York, N.Y.) 2006;12(6):980-7.
2005: Ben Turner; Sonya E Melcher; Timothy J Wilson; David G Norman; David M J Lilley
Induced fit of RNA on binding the L7Ae protein to the kink-turn motif.
RNA (New York, N.Y.) 2005;11(8):1192-200.
2005: Timothy J Wilson; Michelle K Nahas; Taekjip Ha; David M J Lilley
Folding and catalysis of the hairpin ribozyme.
Biochemical Society transactions 2005;33(Pt 3):461-5.
2004: J Carlos Penedo; Timothy J Wilson; Sumedha D Jayasena; Anastasia Khvorova; David M J Lilley
Folding of the natural hammerhead ribozyme is enhanced by interaction of auxiliary elements.
RNA (New York, N.Y.) 2004;10(5):880-8.
2003: Sonya E Melcher; Timothy J Wilson; David M J Lilley
The dynamic nature of the four-way junction of the hepatitis C virus IRES.
RNA (New York, N.Y.) 2003;9(7):809-20.
2002: Daniel A Lafontaine; Timothy J Wilson; Zheng-Yun Zhao; David M J Lilley
Functional group requirements in the probable active site of the VS ribozyme.
Journal of molecular biology 2002;323(1):23-34.
2002: Russell M Crawford; Grant R Budas; Sofija Jovanović; Harri J Ranki; Timothy J Wilson; Anthony M Davies; Aleksandar Jovanović
M-LDH serves as a sarcolemmal K(ATP) channel subunit essential for cell protection against ischemia.
The EMBO journal 2002;21(15):3936-48.
2002: Timothy J Wilson; David M J Lilley
Metal ion binding and the folding of the hairpin ribozyme.
RNA (New York, N.Y.) 2002;8(5):587-600.
2001: Daniel A Lafontaine; Timothy J Wilson; David G Norman; David M J Lilley
The A730 loop is an important component of the active site of the VS ribozyme.
Journal of molecular biology 2001;312(4):663-74.
2001: Timothy J Wilson; Zheng-Yun Zhao; K Maxwell; L Kontogiannis; David M J Lilley
Importance of specific nucleotides in the folding of the natural form of the hairpin ribozyme.
Biochemistry 2001;40(7):2291-302.
2000: Zheng-Yun Zhao; Timothy J Wilson; K Maxwell; David M J Lilley
The folding of the hairpin ribozyme: dependence on the loops and the junction.
RNA (New York, N.Y.) 2000;6(12):1833-46.