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Jay Wimalasena

Research Profile

Chemicals & Drugs

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TOP 3
Ivo Noci; Serena Pillozzi; Elena Lastraioli; Sara Dabizzi; Massimo Giachi; Elena Borrani; Jay Wimalasena; Gian Luigi Taddei; Gianfranco Scarselli; Annarosa Arcangeli
hLH/hCG-receptor expression correlates with in vitro invasiveness in human primary endometrial cancer.
Romaine Fernando; James S Foster; Amber Bible; Anders Ström; Richard G Pestell; Mahadev Rao; Arnold Saxton; Seung Joon Baek; Kiyoshi Yamaguchi; Robert Donnell; Maria Cekanova; Jay Wimalasena
Breast cancer cell proliferation is inhibited by BAD: regulation of cyclin D1.
Tianbing Liu; Jay Wimalasena; Richard L Bowen; Craig S Atwood
Luteinizing hormone receptor mediates neuronal pregnenolone production via up-regulation of steroidogenic acute regulatory protein expression.

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2008: Ivo Noci; Serena Pillozzi; Elena Lastraioli; Sara Dabizzi; Massimo Giachi; Elena Borrani; Jay Wimalasena; Gian Luigi Taddei; Gianfranco Scarselli; Annarosa Arcangeli
hLH/hCG-receptor expression correlates with in vitro invasiveness in human primary endometrial cancer.
Gynecologic oncology 2008;111(3):496-501.
2007: Romaine Fernando; James S Foster; Amber Bible; Anders Ström; Richard G Pestell; Mahadev Rao; Arnold Saxton; Seung Joon Baek; Kiyoshi Yamaguchi; Robert Donnell; Maria Cekanova; Jay Wimalasena
Breast cancer cell proliferation is inhibited by BAD: regulation of cyclin D1.
The Journal of biological chemistry 2007;282(39):28864-73.
2007: Tianbing Liu; Jay Wimalasena; Richard L Bowen; Craig S Atwood
Luteinizing hormone receptor mediates neuronal pregnenolone production via up-regulation of steroidogenic acute regulatory protein expression.
Journal of neurochemistry 2007;100(5):1329-39.
2007: Donald C Henley; M Isbill; R Fernando; James S Foster; Jay Wimalasena
Paclitaxel induced apoptosis in breast cancer cells requires cell cycle transit but not Cdc2 activity.
Cancer chemotherapy and pharmacology 2007;59(2):235-49.
2006: Kiyoshi Yamaguchi; Seong-Ho Lee; Jong-Sik Kim; Jay Wimalasena; Shigetaka Kitajima; Seung Joon Baek
Activating transcription factor 3 and early growth response 1 are the novel targets of LY294002 in a phosphatidylinositol 3-kinase-independent pathway.
Cancer research 2006;66(4):2376-84.
2005: Antonin Bukovsky; Michael R Caudle; Marta Svetlikova; Jay Wimalasena; Maria E Ayala; Roberto Dominguez
Oogenesis in adult mammals, including humans: a review.
Endocrine 2005;26(3):301-16.
2004: Johan Hartman; Patrick Müller; James S Foster; Jay Wimalasena; Jan-�ke GUSTAFSSON; Anders Ström
HES-1 inhibits 17beta-estradiol and heregulin-beta1-mediated upregulation of E2F-1.
Oncogene 2004;23(54):8826-33.
2004: Romaine Ingrid Fernando; Jay Wimalasena
Estradiol abrogates apoptosis in breast cancer cells through inactivation of BAD: Ras-dependent nongenomic pathways requiring signaling through ERK and Akt.
Molecular biology of the cell 2004;15(7):3266-84.
2004: Anders Ström; Johan Hartman; James S Foster; Silke Kietz; Jay Wimalasena; Jan-�ke GUSTAFSSON
Estrogen receptor beta inhibits 17beta-estradiol-stimulated proliferation of the breast cancer cell line T47D.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(6):1566-71.
2003: James S Foster; Romaine I Fernando; Noriko Ishida; Keiichi I Nakayama; Jay Wimalasena
Estrogens down-regulate p27Kip1 in breast cancer cells through Skp2 and through nuclear export mediated by the ERK pathway.
The Journal of biological chemistry 2003;278(42):41355-66.
2003: Antonin Bukovsky; Michael R Caudle; Maria Cekanova; Romaine I Fernando; Jay Wimalasena; James S Foster; Donald C Henley; Robert F Elder
Placental expression of estrogen receptor beta and its hormone binding variant--comparison with estrogen receptor alpha and a role for estrogen receptors in asymmetric division and differentiation of estrogen-dependent cells.
Reproductive biology and endocrinology : RB&E 2003;1():36.
2003: Antonin Bukovsky; Maria Cekanova; Michael R Caudle; Jay Wimalasena; James S Foster; Donald C Henley; Robert F Elder
Expression and localization of estrogen receptor-alpha protein in normal and abnormal term placentae and stimulation of trophoblast differentiation by estradiol.
Reproductive biology and endocrinology : RB&E 2003;1():13.
2002: Antonin Bukovsky; Maria Cekanova; Michael R Caudle; Jay Wimalasena; James S Foster; Jeffrey A Keenan; Robert F Elder
Variability of placental expression of cyclin E low molecular weight variants.
Biology of reproduction 2002;67(2):568-74.
2002: Shamila Ahamed; James S Foster; Antonin Bukovsky; J Alan Diehl; Jay Wimalasena
Removal of Cdk inhibitors through both sequestration and downregulation in zearalenone-treated MCF-7 breast cancer cells.
Molecular carcinogenesis 2002;34(1):45-58.
2002: Antonin Bukovsky; Maria E Ayala; Roberto Dominguez; Jeffrey A Keenan; Jay Wimalasena; Robert F Elder; Michael R Caudle
Changes of ovarian interstitial cell hormone receptors and behavior of resident mesenchymal cells in developing and adult rats with steroid-induced sterility.
Steroids 2002;67(3-4):277-89.
2001: Antonin Bukovsky; Michael R Caudle; Jay Wimalasena; Jeffrey A Keenan; Robert F Elder
The role of the host-tumor interface and cell hybridization in invasive cancer.
Medical hypotheses 2001;57(6):729-35.
2001: James S Foster; Donald C Henley; Shamila Ahamed; Jay Wimalasena
Estrogens and cell-cycle regulation in breast cancer.
Trends in endocrinology and metabolism: TEM 2001;12(7):320-7.
2001: Shamila Ahamed; James S Foster; Antonin Bukovsky; Jay Wimalasena
Signal transduction through the Ras/Erk pathway is essential for the mycoestrogen zearalenone-induced cell-cycle progression in MCF-7 cells.
Molecular carcinogenesis 2001;30(2):88-98.
2001: James S Foster; Donald C Henley; Antonin Bukovsky; Prem Seth; Jay Wimalasena
Multifaceted regulation of cell cycle progression by estrogen: regulation of Cdk inhibitors and Cdc25A independent of cyclin D1-Cdk4 function.
Molecular and cellular biology 2001;21(3):794-810.
2001: Antonin Bukovsky; Michael R Caudle; Jeffrey A Keenan; Nirmala B Upadhyaya; S E Van Meter; Jay Wimalasena; Robert F Elder
Association of mesenchymal cells and immunoglobulins with differentiating epithelial cells.
BMC developmental biology 2001;1():11.
2000: Antonin Bukovsky; Maria E Ayala; Roberto Dominguez; Jeffrey A Keenan; Jay Wimalasena; PP McKenzie; Michael R Caudle
Postnatal androgenization induces premature aging of rat ovaries.
Steroids 2000;65(4):190-205.
1999: Antonin Bukovsky; Michael R Caudle; Jeffrey A Keenan; Jay Wimalasena; PP McKenzie
Thy-1 differentiation protein and monocyte-derived cells during regeneration and aging of human placental villi.
American journal of reproductive immunology (New York, N.Y. : 1989) 1999;42(3):135-52.
1999: T H Wang; DM Popp; H S Wang; M Saitoh; J G Mural; Donald C Henley; H Ichijo; Jay Wimalasena
Microtubule dysfunction induced by paclitaxel initiates apoptosis through both c-Jun N-terminal kinase (JNK)-dependent and -independent pathways in ovarian cancer cells.
The Journal of biological chemistry 1999;274(12):8208-16.
1998: PP McKenzie; James S Foster; S House; Antonin Bukovsky; Michael R Caudle; Jay Wimalasena
Expression of G1 cyclins and cyclin-dependent kinase-2 activity during terminal differentiation of cultured human trophoblast.
Biology of reproduction 1998;58(5):1283-9.
1998: T H Wang; H S Wang; H Ichijo; P Giannakakou; James S Foster; T Fojo; Jay Wimalasena
Microtubule-interfering agents activate c-Jun N-terminal kinase/stress-activated protein kinase through both Ras and apoptosis signal-regulating kinase pathways.
The Journal of biological chemistry 1998;273(9):4928-36.
1997: Craig Dees; James S Foster; Shamila Ahamed; Jay Wimalasena
Dietary estrogens stimulate human breast cells to enter the cell cycle.
Environmental health perspectives 1997;105 Suppl 3():633-6.
1997: Craig Dees; Minoo D F Askari; James S Foster; Shamila Ahamed; Jay Wimalasena
DDT mimicks estradiol stimulation of breast cancer cells to enter the cell cycle.
Molecular carcinogenesis 1997;18(2):107-14.
1996: A Bukovský; Michael R Caudle; Jeffrey A Keenan; Jay Wimalasena; N B Upadhyaya; S E van Meter
Is irregular regression of corpora lutea in climacteric women caused by age-induced alterations in the "tissue control system"?
American journal of reproductive immunology (New York, N.Y. : 1989) 1996;36(6):327-41.
1996: M R Cameron; James S Foster; Antonin Bukovsky; Jay Wimalasena
Activation of mitogen-activated protein kinases by gonadotropins and cyclic adenosine 5'-monophosphates in porcine granulosa cells.
Biology of reproduction 1996;55(1):111-9.
1996: James S Foster; Jay Wimalasena
Estrogen regulates activity of cyclin-dependent kinases and retinoblastoma protein phosphorylation in breast cancer cells.
Molecular endocrinology (Baltimore, Md.) 1996;10(5):488-98.
1995: P P McKenzie; J D McClaran; Michael R Caudle; A Fukuda; Jay Wimalasena
Alcohol inhibits epidermal growth factor-stimulated progesterone secretion from human granulosa cells.
Alcoholism, clinical and experimental research 1995;19(6):1382-8.
1995: A Bukovský; Michael R Caudle; Jeffrey A Keenan; Jay Wimalasena; N B Upadhyaya; S E Van Meter
Is corpus luteum regression an immune-mediated event? Localization of immune system components and luteinizing hormone receptor in human corpora lutea.
Biology of reproduction 1995;53(6):1373-84.
1995: A Bukovský; Michael R Caudle; Jeffrey A Keenan; Jay Wimalasena; James S Foster; S E Van Meter
Quantitative evaluation of the cell cycle-related retinoblastoma protein and localization of Thy-1 differentiation protein and macrophages during follicular development and atresia, and in human corpora lutea.
Biology of reproduction 1995;52(4):776-92.
1995: A Bukovský; Jeffrey A Keenan; Michael R Caudle; Jay Wimalasena; N B Upadhyaya; S E Van Meter
Immunohistochemical studies of the adult human ovary: possible contribution of immune and epithelial factors to folliculogenesis.
American journal of reproductive immunology (New York, N.Y. : 1989) 1995;33(4):323-40.
1995: Antonin Bukovsky; Michael R Caudle; Jeffrey A Keenan; Jay Wimalasena; James S Foster; N B Upadhyaya; S E van Meter
Expression of cell cycle regulatory proteins (p53, pRb) in the human female genital tract.
Journal of assisted reproduction and genetics 1995;12(2):123-31.
1995: M R Cameron; Michael R Caudle; W R Sullivan; J J Peluso; Jay Wimalasena
The steroidogenic and morphological effects of paclitaxel on cultured ovarian cancer cells.
Oncology research 1995;7(3-4):145-56.
1994: Jay Wimalasena; F Beams; Michael R Caudle
Ethanol modulates the hormone secretory responses induced by epidermal growth factor in choriocarcinoma cells.
Alcoholism, clinical and experimental research 1994;18(6):1448-55.
1994: Jay Wimalasena
Ethanol has direct effects on human choriocarcinoma cell steroid hormone secretion.
Alcoholism, clinical and experimental research 1994;18(2):369-74.
1993: A Bukovský; T T Chen; Jay Wimalasena; Michael R Caudle
Cellular localization of luteinizing hormone receptor immunoreactivity in the ovaries of immature, gonadotropin-primed and normal cycling rats.
Biology of reproduction 1993;48(6):1367-82.
1993: Jay Wimalasena; D Meehan; R Dostal; M de Silva
Selective inhibition of luteinizing hormone action by ethanol in cultured human granulosa cells.
Alcoholism, clinical and experimental research 1993;17(2):340-4.
1993: Jay Wimalasena; D Meehan; R Dostal; James S Foster; M Cameron; M Smith
Growth factors interact with estradiol and gonadotropins in the regulation of ovarian cancer cell growth and growth factor receptors.
Oncology research 1993;5(8):325-37.
1992: Jay Wimalasena; R Dostal; D Meehan
Gonadotropins, estradiol, and growth factors regulate epithelial ovarian cancer cell growth.
Gynecologic oncology 1992;46(3):345-50.
1992: K Indrapichate; D Meehan; T A Lane; Shaoyou Chu; C V Rao; D Johnson; T T Chen; Jay Wimalasena
Biological actions of monoclonal luteinizing hormone/human chorionic gonadotropin receptor antibodies.
Biology of reproduction 1992;46(2):265-78.
1991: Jay Wimalasena; D Meehan; C Cavallo
Human epithelial ovarian cancer cell steroid secretion and its control by gonadotropins.
Gynecologic oncology 1991;41(1):56-63.
1990: K Alpaugh; K Indrapichate; J A Abel; Ronald A Rimerman; Jay Wimalasena
Purification and characterization of the human ovarian LH/hCG receptor and comparison of the properties of mammalian LH/hCG receptors.
Biochemical pharmacology 1990;40(9):2093-103.
1990: S Saxena; D Meehan; PonJola Coney; Jay Wimalasena
Ethanol has direct inhibitory effects on steroidogenesis in human granulosa cells: specific inhibition of LH action.
Alcoholism, clinical and experimental research 1990;14(4):522-7.
1986: Jay Wimalasena; J A Abel; J P Wiebe; T T Chen
The porcine ovarian luteinizing hormone/human chorionic gonadotropin receptor II. Is the purified receptor an oligomer of identical subunits?
The Journal of biological chemistry 1986;261(20):9416-20.
1985: Jay Wimalasena; P Moore; J P Wiebe; J Abel; T T Chen
The porcine LH/hCG receptor. Characterization and purification.
The Journal of biological chemistry 1985;260(19):10689-97.