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Cheryl Winkler

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Sophie Limou; Matthieu Montes; Stephen J O'Brien; François Schachter; Hanneke Schuitemaker; Efe Sezgin; Jean-Louis Spadoni; Lieng Taing; Jennifer L Troyer; Leonard H van den Berg; Daniëlle van Manen; Mark L van Natta; Jan H Veldink; Cheryl A Winkler; Ping An; Susan Buchbinder; Cédric Coulonges; Olivier Delaneau; Jean-François Delfraissy; philippe froguel; Douglas A Jabs; Taoufik labib; Sigrid Le Clerc; Jean-François Zagury
Multicohort genomewide association study reveals a new signal of protection against HIV-1 acquisition.
Kai Zhao; Cheryl A Winkler; Yasuko Ishida; Taras K Oleksyk; Alfred L Roca
Evidence for selection at HIV host susceptibility genes in a West Central African human population.
Ping An; Susan P Buchbinder; Sharyne Donfield; James J Goedert; Gregory D Kirk; Rongling Li; George W Nelson; Stephen J O'Brien; John Phair; Ram Samudralal; Efe Sezgin; Munehisa Takahashi; Jennifer L Troyer; Ji Ming Wang; Teizo Yoshimura; Cheryl A Winkler
Role of exonic variation in chemokine receptor genes on AIDS: CCRL2 F167Y association with pneumocystis pneumonia.

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All Publications

2012: Sophie Limou; Matthieu Montes; Stephen J O'Brien; François Schachter; Hanneke Schuitemaker; Efe Sezgin; Jean-Louis Spadoni; Lieng Taing; Jennifer L Troyer; Leonard H van den Berg; Daniëlle van Manen; Mark L van Natta; Jan H Veldink; Cheryl A Winkler; Ping An; Susan Buchbinder; Cédric Coulonges; Olivier Delaneau; Jean-François Delfraissy; philippe froguel; Douglas A Jabs; Taoufik labib; Sigrid Le Clerc; Jean-François Zagury
Multicohort genomewide association study reveals a new signal of protection against HIV-1 acquisition.
The Journal of infectious diseases 2012;205(7):1155-62.
2012: Kai Zhao; Cheryl A Winkler; Yasuko Ishida; Taras K Oleksyk; Alfred L Roca
Evidence for selection at HIV host susceptibility genes in a West Central African human population.
BMC evolutionary biology 2012;12():237.
2011: Ping An; Susan P Buchbinder; Sharyne Donfield; James J Goedert; Gregory D Kirk; Rongling Li; George W Nelson; Stephen J O'Brien; John Phair; Ram Samudralal; Efe Sezgin; Munehisa Takahashi; Jennifer L Troyer; Ji Ming Wang; Teizo Yoshimura; Cheryl A Winkler
Role of exonic variation in chemokine receptor genes on AIDS: CCRL2 F167Y association with pneumocystis pneumonia.
PLoS genetics 2011;7(10):e1002328.
2011: Paradise Madlala; Koleka Patience Mlisana; Lise Werner; Cheryl A Winkler; Salim S Abdool-Karim; Ping An; Frauke Christ; zeger debyser; Rik Gijsbers; Anneleen Hombrouck; Thumbi Ndung'u
Association of polymorphisms in the LEDGF/p75 gene (PSIP1) with susceptibility to HIV-1 infection and disease progression.
AIDS (London, England) 2011;25(14):1711-9.
2011: Jennifer L Troyer; George W Nelson; James Lautenberger; Leslie Chinn; Carl McIntosh; Randall C Johnson; Efe Sezgin; Bailey Kessing; Michael Malasky; Sher L Hendrickson; Guan Li; Joan U Pontius; Minzhong Tang; Ping An; Cheryl A Winkler; Sophie Limou; Sigrid Le Clerc; Olivier Delaneau; Jean-François Zagury; Hanneke Schuitemaker; Daniëlle van Manen; Jay H Bream; Edward D Gomperts; Susan Buchbinder; James J Goedert; Gregory D Kirk; Stephen J O'Brien
Genome-wide association study implicates PARD3B-based AIDS restriction.
The Journal of infectious diseases 2011;203(10):1491-502.
2010: Giulio Genovese; David J Friedman; Michael D Ross; Laurence Lecordier; Pierrick Uzureau; Barry I Freedman; Donald W Bowden; Carl D Langefeld; Taras K Oleksyk; Andrea L Uscinski Knob; Andrea J Bernhardy; Pamela J Hicks; George W Nelson; Benoit Vanhollebeke; Cheryl A Winkler; Jeffrey Kopp; Etienne Pays; Martin R Pollak
Association of trypanolytic ApoL1 variants with kidney disease in African Americans.
Science (New York, N.Y.) 2010;329(5993):841-5.
2010: George W Nelson; Barry I Freedman; Donald W Bowden; Carl D Langefeld; Ping An; Pamela J Hicks; Meredith A Bostrom; Randall C Johnson; Jeffrey B Kopp; Cheryl A Winkler
Dense mapping of MYH9 localizes the strongest kidney disease associations to the region of introns 13 to 15.
Human molecular genetics 2010;19(9):1805-15.
2010: Cheryl A Winkler; George Nelson; Taras K Oleksyk; M Berenice Nava; Jeffrey B Kopp
Genetics of focal segmental glomerulosclerosis and human immunodeficiency virus-associated collapsing glomerulopathy: the role of MYH9 genetic variation.
Seminars in nephrology 2010;30(2):111-25.
2010: Ping An; Cheryl A Winkler
Host genes associated with HIV/AIDS: advances in gene discovery.
Trends in genetics : TIG 2010;26(3):119-31.
2010: Taras K Oleksyk; George W Nelson; Ping An; Jeffrey B Kopp; Cheryl A Winkler
Worldwide distribution of the MYH9 kidney disease susceptibility alleles and haplotypes: evidence of historical selection in Africa.
PloS one 2010;5(7):e11474.
2009: Ping An; Randall Johnson; John Phair; Gregory D Kirk; XIAOFANG YU; Sharyne Donfield; Susan Buchbinder; James J Goedert; Cheryl A Winkler
APOBEC3B deletion and risk of HIV-1 acquisition.
The Journal of infectious diseases 2009;200(7):1054-8.
2009: Xiuchan Guo; Randall C Johnson; Hong Deng; Jian Liao; Li Guan; George W Nelson; Mingzhong Tang; Yuming Zheng; Guy de The; Stephen J O'Brien; Cheryl A Winkler; Yi Zeng
Evaluation of nonviral risk factors for nasopharyngeal carcinoma in a high-risk population of Southern China.
International journal of cancer. Journal international du cancer 2009;124(12):2942-7.
2009: Cheryl A Winkler; Ping An; Randall Johnson; George W Nelson; Gregory D Kirk
Expression of Duffy antigen receptor for chemokines (DARC) has no effect on HIV-1 acquisition or progression to AIDS in African Americans.
Cell host & microbe 2009;5(5):411-3; author reply 418-9.
2008: Ping An; Chloe L Thio; Gregory D Kirk; Sharyne Donfield; James J Goedert; Cheryl A Winkler
Regulatory polymorphisms in the interleukin-18 promoter are associated with hepatitis C virus clearance.
The Journal of infectious diseases 2008;198(8):1159-65.
2008: Xiuchan Guo; Stephen J O'Brien; Yi Zeng; George W Nelson; Cheryl A Winkler
GSTM1 and GSTT1 gene deletions and the risk for nasopharyngeal carcinoma in Han Chinese.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2008;17(7):1760-3.
2008: H B Hutcheson; J A Lautenberger; George W Nelson; Joan U Pontius; B D Kessing; Cheryl A Winkler; M W Smith; R Johnson; Robert Stephens; J Phair; James J Goedert; S Donfield; Stephen J O'Brien
Detecting AIDS restriction genes: from candidate genes to genome-wide association discovery.
Vaccine 2008;26(24):2951-65.
2007: Louise M McKenzie; Sher L Hendrickson; William A Briggs; Richard A Dart; Stephen M Korbet; Michele H Mokrzycki; Paul L Kimmel; Tejinder S Ahuja; Jeffrey S Berns; Eric E Simon; Michael C Smith; Howard Trachtman; Donna M Michel; Jeffrey R Schelling; Monique Cho; Yu C Zhou; Elizabeth Binns-Roemer; Gregory D Kirk; Jeffrey B Kopp; Cheryl A Winkler
NPHS2 variation in sporadic focal segmental glomerulosclerosis.
Journal of the American Society of Nephrology : JASN 2007;18(11):2987-95.
2007: Ping An; Li Hua Wang; Holli Hutcheson-Dilks; George Nelson; Sharyne Donfield; James J Goedert; Charles Rinaldo; Susan Buchbinder; Gregory D Kirk; Stephen J O'Brien; Cheryl A Winkler
Regulatory polymorphisms in the cyclophilin A gene, PPIA, accelerate progression to AIDS.
PLoS pathogens 2007;3(6):e88.
2007: Xing Li; Bert Gold; Colm O'hUigin; Felipe Diaz-Griffero; Byeongwoon Song; Zhihai Si; Yuan Li; Wen Yuan; Matthew Stremlau; Claudia C Mische; Hassan Javanbakht; Mark Scally; Cheryl A Winkler; Michael Dean; Joseph Sodroski
Unique features of TRIM5alpha among closely related human TRIM family members.
Virology 2007;360(2):419-33.
2007: Ping An; Priya Duggal; Li Hua Wang; Stephen J O'Brien; Sharyne Donfield; James J Goedert; John Phair; Susan Buchbinder; Gregory D Kirk; Cheryl A Winkler
Polymorphisms of CUL5 are associated with CD4+ T cell loss in HIV-1 infected individuals.
PLoS genetics 2007;3(1):e19.
2006: Hassan Javanbakht; Ping An; Bert Gold; Desiree C Petersen; Colm O'hUigin; George W Nelson; Stephen J O'Brien; Gregory D Kirk; Roger Detels; Susan Buchbinder; Sharyne Donfield; Sergey Shulenin; Byeongwoon Song; Michel Perron; Matthew Stremlau; Joseph Sodroski; Michael Dean; Cheryl A Winkler
Effects of human TRIM5alpha polymorphisms on antiretroviral function and susceptibility to human immunodeficiency virus infection.
Virology 2006;354(1):15-27.
2006: Xiu-chan Guo; Stephen J O'Brien; Cheryl A Winkler; Kevin Scott; Holli Hutcheson; Victor David; Bailey Kessing; Yu-Ming Zheng; Jian Liao; Yan Lui; de The Guy; Yi Zeng
[Association study of chromosome 4 STRs polymorphisms with nasopharyngeal carcinoma].
Yi chuan = Hereditas / Zhongguo yi chuan xue hui bian ji 2006;28(7):783-90.
2006: William S Modi; James Lautenberger; Ping An; Kevin Scott; James J Goedert; Gregory D Kirk; Susan Buchbinder; John Phair; Sharyne Donfield; Stephen J O'Brien; Cheryl A Winkler
Genetic variation in the CCL18-CCL3-CCL4 chemokine gene cluster influences HIV Type 1 transmission and AIDS disease progression.
American journal of human genetics 2006;79(1):120-8.
2006: Xiu-chan Guo; Kevin Scott; Yan Liu; Michael Dean; Victor David; George W Nelson; Randall C Johnson; Holli H Dilks; James Lautenberger; Bailey Kessing; Janice Martenson; Li Guan; Shan Sun; Hong Deng; Yuming Zheng; Guy de The; Jian Liao; Yi Zeng; Stephen J O'Brien; Cheryl A Winkler
Genetic factors leading to chronic Epstein-Barr virus infection and nasopharyngeal carcinoma in South East China: study design, methods and feasibility.
Human genomics 2006;2(6):365-75.
2005: William S Modi; Kevin Scott; James J Goedert; David Vlahov; Susan Buchbinder; Roger Detels; Sharyne Donfield; Stephen J O'Brien; Cheryl A Winkler
Haplotype analysis of the SDF-1 (CXCL12) gene in a longitudinal HIV-1/AIDS cohort study.
Genes and immunity 2005;6(8):691-8.
2005: Eric S Daar; Henry S Lynn; Sharyne Donfield; Alice Lail; Stephen J O'Brien; Wei Huang; Cheryl A Winkler
Stromal cell-derived factor-1 genotype, coreceptor tropism, and HIV type 1 disease progression.
The Journal of infectious diseases 2005;192(9):1597-605.
2005: Byeongwoon Song; Bert Gold; Colm O'hUigin; Hassan Javanbakht; Xing Li; Matthew Stremlau; Cheryl A Winkler; Michael Dean; Joseph Sodroski
The B30.2(SPRY) domain of the retroviral restriction factor TRIM5alpha exhibits lineage-specific length and sequence variation in primates.
Journal of virology 2005;79(10):6111-21.
2005: Priya Duggal; Cheryl A Winkler; Ping An; XIAOFANG YU; Homayoon Farzadegan; Stephen J O'Brien; Terri H beaty; David Vlahov
The effect of RANTES chemokine genetic variants on early HIV-1 plasma RNA among African American injection drug users.
Journal of acquired immune deficiency syndromes (1999) 2005;38(5):584-9.
2004: Cheryl A Winkler; Houria Hendel; Mary Carrington; Michael W Smith; George W Nelson; Stephen J O'brien; John Phair; David Vlahov; Lisa P Jacobson; Jay Rappaport; Alexandre Vasilescu; Sebastien Bertin-Maghit; Ping An; Wei Lu; Jean-Marie Andrieu; François Schächter; Amu Therwath; Jean-François Zagury
Dominant effects of CCR2-CCR5 haplotypes in HIV-1 disease progression.
Journal of acquired immune deficiency syndromes (1999) 2004;37(4):1534-8.
2004: Ping An; Gabriela Bleiber; Priya Duggal; George Nelson; Margaret May; Bastien Mangeat; Irene Alobwede; Didier Trono; David Vlahov; Sharyne Donfield; James J Goedert; John Phair; Susan Buchbinder; Stephen J O'Brien; Amalio Telenti; Cheryl A Winkler
APOBEC3G genetic variants and their influence on the progression to AIDS.
Journal of virology 2004;78(20):11070-6.
2004: Cheryl A Winkler; Ping An; Stephen J O'Brien
Patterns of ethnic diversity among the genes that influence AIDS.
Human molecular genetics 2004;13 Spec No 1():R9-19.
2003: William S Modi; James J Goedert; Steffanie A Strathdee; Susan Buchbinder; Roger Detels; Sharyne Donfield; Stephen J O'Brien; Cheryl A Winkler
MCP-1-MCP-3-Eotaxin gene cluster influences HIV-1 transmission.
AIDS (London, England) 2003;17(16):2357-65.
2003: Ping An; David Vlahov; Joseph B Margolick; John Phair; Thomas R O'Brien; James Lautenberger; Stephen J O'Brien; Cheryl A Winkler
A tumor necrosis factor-alpha-inducible promoter variant of interferon-gamma accelerates CD4+ T cell depletion in human immunodeficiency virus-1-infected individuals.
The Journal of infectious diseases 2003;188(2):228-31.
2003: Priya Duggal; Ping An; Terri H beaty; Steffanie A Strathdee; Homayoon Farzadegan; Richard B Markham; LISETTE JOHNSON-HILL; Stephen J O'Brien; David Vlahov; Cheryl A Winkler
Genetic influence of CXCR6 chemokine receptor alleles on PCP-mediated AIDS progression among African Americans.
Genes and immunity 2003;4(4):245-50.
2003: William S Modi; Thomas R O'Brien; David Vlahov; Susan Buchbinder; Edward D Gomperts; John Phair; Stephen J O'Brien; Cheryl A Winkler
Haplotype diversity in the interleukin-4 gene is not associated with HIV-1 transmission and AIDS progression.
Immunogenetics 2003;55(3):157-64.
2002: Ping An; George W Nelson; Lihua Wang; Sharyne Donfield; James J Goedert; John Phair; David Vlahov; Susan Buchbinder; William L Farrar; William S Modi; Stephen J O'Brien; Cheryl A Winkler
Modulating influence on HIV/AIDS by interacting RANTES gene variants.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(15):10002-7.
2001: Danièle Dubois-Laforgue; Houria Hendel; Sophie Caillat-Zucman; Jean-François Zagury; Cheryl A Winkler; Christian Boitard; José Timsit
A common stromal cell-derived factor-1 chemokine gene variant is associated with the early onset of type 1 diabetes.
Diabetes 2001;50(5):1211-3.
2001: Houria Hendel; Cheryl A Winkler; Ping An; E Roemer-Binns; G Nelson; PM Haumont; S O'Brien; K Khalilli; Daniel Zagury; Jay Rappaport; Jean-François Zagury
Validation of genetic case-control studies in AIDS and application to the CX3CR1 polymorphism.
Journal of acquired immune deficiency syndromes (1999) 2001;26(5):507-11.
2001: Eric S Daar; Henry S Lynn; Sharyne Donfield; Edward D Gomperts; Margaret W Hilgartner; W Keith Hoots; D Chernoff; S Arkin; W Y Wong; Cheryl A Winkler
Relation between HIV-1 and hepatitis C viral load in patients with hemophilia.
Journal of acquired immune deficiency syndromes (1999) 2001;26(5):466-72.
2001: Eric S Daar; Henry S Lynn; Sharyne Donfield; Edward D Gomperts; Stephen J O'Brien; Margaret W Hilgartner; W Keith Hoots; D Chernoff; S Arkin; W Y Wong; Cheryl A Winkler
Hepatitis C virus load is associated with human immunodeficiency virus type 1 disease progression in hemophiliacs.
The Journal of infectious diseases 2001;183(4):589-95.
2000: H D Shin; Cheryl A Winkler; J C Stephens; Jay H Bream; H Young; James J Goedert; Thomas R O'Brien; David Vlahov; Susan Buchbinder; Janis V Giorgi; Charles Rinaldo; Sharyne Donfield; A Willoughby; Stephen J O'Brien; Michael W Smith
Genetic restriction of HIV-1 pathogenesis to AIDS by promoter alleles of IL10.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(26):14467-72.
2000: Ping An; Maureen P Martin; George W Nelson; Mary Carrington; Michael W Smith; K Gong; David Vlahov; Stephen J O'Brien; Cheryl A Winkler
Influence of CCR5 promoter haplotypes on AIDS progression in African-Americans.
AIDS (London, England) 2000;14(14):2117-22.
1999: Eric S Daar; Henry S Lynn; Sharyne Donfield; Edward D Gomperts; Margaret W Hilgartner; Keith Hoots; D Chernoff; Cheryl A Winkler; Stephen J O'Brien
Effects of plasma HIV RNA, CD4+ T lymphocytes, and the chemokine receptors CCR5 and CCR2b on HIV disease progression in hemophiliacs. Hemophilia Growth and Development Study.
Journal of acquired immune deficiency syndromes (1999) 1999;21(4):317-25.
1999: Houria Hendel; Sophie Caillat-Zucman; H Lebuanec; Mary Carrington; S O'Brien; Jean-Marie Andrieu; François Schächter; Daniel Zagury; Jay Rappaport; Cheryl A Winkler; George W Nelson; Jean-François Zagury
New class I and II HLA alleles strongly associated with opposite patterns of progression to AIDS.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(11):6942-6.
1998: Maureen P Martin; Michael Dean; Michael W Smith; Cheryl A Winkler; B Gerrard; Nelson L Michael; B Lee; R W Doms; Joseph B Margolick; Susan Buchbinder; James J Goedert; Thomas R O'Brien; Margaret W Hilgartner; David Vlahov; Stephen J O'Brien; Mary Carrington
Genetic acceleration of AIDS progression by a promoter variant of CCR5.
Science (New York, N.Y.) 1998;282(5395):1907-11.
1998: Houria Hendel; N Hénon; H Lebuanec; Abderrahim LACHGAR; H Poncelet; Sophie Caillat-Zucman; Cheryl A Winkler; Michael W Smith; L Kenefic; S O'Brien; W Lu; Jean-Marie Andrieu; Daniel Zagury; François Schächter; Jay Rappaport; Jean-François Zagury
Distinctive effects of CCR5, CCR2, and SDF1 genetic polymorphisms in AIDS progression.
Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association 1998;19(4):381-6.
1998: Cheryl A Winkler; William S Modi; Michael W Smith; George W Nelson; X Wu; Mary Carrington; Michael Dean; T Honjo; K Tashiro; Yabe Daisuke; Susan Buchbinder; E Vittinghoff; James J Goedert; Thomas R O'Brien; Lisa P Jacobson; Roger Detels; Sharyne Donfield; A Willoughby; Edward D Gomperts; David Vlahov; John Phair; Stephen J O'Brien
Genetic restriction of AIDS pathogenesis by an SDF-1 chemokine gene variant. ALIVE Study, Hemophilia Growth and Development Study (HGDS), Multicenter AIDS Cohort Study (MACS), Multicenter Hemophilia Cohort Study (MHCS), San Francisco City Cohort (SFCC)
Science (New York, N.Y.) 1998;279(5349):389-93.
1997: Michael W Smith; Mary Carrington; Cheryl A Winkler; D Lomb; M Dean; G Huttley; Stephen J O'Brien
CCR2 chemokine receptor and AIDS progression.
Nature medicine 1997;3(10):1052-3.
1997: Michael W Smith; Michael Dean; Mary Carrington; Cheryl A Winkler; G A Huttley; D A Lomb; James J Goedert; Thomas R O'Brien; Lisa P Jacobson; Richard A Kaslow; Susan Buchbinder; E Vittinghoff; David Vlahov; Keith Hoots; Margaret W Hilgartner; Stephen J O'Brien
Contrasting genetic influence of CCR2 and CCR5 variants on HIV-1 infection and disease progression. Hemophilia Growth and Development Study (HGDS), Multicenter AIDS Cohort Study (MACS), Multicenter Hemophilia Cohort Study (MHCS), San Francisco City Cohort (SFCC), ALIVE Study.
Science (New York, N.Y.) 1997;277(5328):959-65.
1996: M Dean; Mary Carrington; Cheryl A Winkler; G A Huttley; Michael W Smith; R Allikmets; James J Goedert; S P Buchbinder; Eric Vittinghoff; Edward D Gomperts; Sharyne Donfield; David Vlahov; Richard A Kaslow; Alfred J Saah; Charles Rinaldo; R Detels; Stephen J O'Brien
Genetic restriction of HIV-1 infection and progression to AIDS by a deletion allele of the CKR5 structural gene. Hemophilia Growth and Development Study, Multicenter AIDS Cohort Study, Multicenter Hemophilia Cohort Study, San Francisco City Cohort, ALIVE Study.
Science (New York, N.Y.) 1996;273(5283):1856-62.