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Peter Winstanley

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Chemicals & Drugs

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Paul M O'Neill; Alison E Shone; Deborah Stanford; Gemma Nixon; Eghbaleh Asadollahy; B Kevin Park; James L Maggs; Phil Roberts; Paul A Stocks; Giancarlo Biagini; Patrick G Bray; Jill Davies; Neil Berry; Charlotte Hall; Karen Rimmer; Peter A Winstanley; Stephen Hindley; Ramesh B Bambal; Charles B Davis; Martin Bates; Stephanie L Gresham; Richard A Brigandi; Federico M Gomez-de-Las-Heras; Domingo V Gargallo; Silvia Parapini; Livia Vivas; Hollie Lander; Donatella Taramelli; Stephen A Ward
Synthesis, antimalarial activity, and preclinical pharmacology of a novel series of 4'-fluoro and 4'-chloro analogues of amodiaquine. Identification of a suitable "back-up" compound for N-tert-butyl isoquine.
Alisa P Alker; Jonathan Juliano; Steven R Meshnick; Andrew Owen; Edwin Ochong; David J Bell; David J Johnson; Umberto D'Alessandro; Modest Mulenga; Sant Muangnoicharoen; Jean-Pierre Van geertruyden; Peter A Winstanley; Patrick G Bray; Stephen A Ward
Plasmodium falciparum and dihydrofolate reductase I164L mutations in Africa.
Paul M O'Neill; B Kevin Park; Alison E Shone; James L Maggs; Phillip Roberts; Paul A Stocks; Giancarlo A Biagini; Patrick G Bray; Peter Gibbons; Neil Berry; Peter A Winstanley; Amira Mukhtar; Richard Bonar-Law; Stephen Hindley; Ramesh B Bambal; Charles B Davis; Martin Bates; Timothy K Hart; Stephanie L Gresham; Ron M Lawrence; Richard A Brigandi; Federico M Gomez-delas-Heras; Domingo V Gargallo; Stephen A Ward
Candidate selection and preclinical evaluation of N-tert-butyl isoquine (GSK369796), an affordable and effective 4-aminoquinoline antimalarial for the 21st century.

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All Publications

2009: Paul M O'Neill; Alison E Shone; Deborah Stanford; Gemma Nixon; Eghbaleh Asadollahy; B Kevin Park; James L Maggs; Phil Roberts; Paul A Stocks; Giancarlo Biagini; Patrick G Bray; Jill Davies; Neil Berry; Charlotte Hall; Karen Rimmer; Peter A Winstanley; Stephen Hindley; Ramesh B Bambal; Charles B Davis; Martin Bates; Stephanie L Gresham; Richard A Brigandi; Federico M Gomez-de-Las-Heras; Domingo V Gargallo; Silvia Parapini; Livia Vivas; Hollie Lander; Donatella Taramelli; Stephen A Ward
Synthesis, antimalarial activity, and preclinical pharmacology of a novel series of 4'-fluoro and 4'-chloro analogues of amodiaquine. Identification of a suitable "back-up" compound for N-tert-butyl isoquine.
Journal of medicinal chemistry 2009;52(7):1828-44.
2009: Alisa P Alker; Jonathan Juliano; Steven R Meshnick; Andrew Owen; Edwin Ochong; David J Bell; David J Johnson; Umberto D'Alessandro; Modest Mulenga; Sant Muangnoicharoen; Jean-Pierre Van geertruyden; Peter A Winstanley; Patrick G Bray; Stephen A Ward
Plasmodium falciparum and dihydrofolate reductase I164L mutations in Africa.
Antimicrobial agents and chemotherapy 2009;53(4):1722; author reply 1722-3.
2009: Paul M O'Neill; B Kevin Park; Alison E Shone; James L Maggs; Phillip Roberts; Paul A Stocks; Giancarlo A Biagini; Patrick G Bray; Peter Gibbons; Neil Berry; Peter A Winstanley; Amira Mukhtar; Richard Bonar-Law; Stephen Hindley; Ramesh B Bambal; Charles B Davis; Martin Bates; Timothy K Hart; Stephanie L Gresham; Ron M Lawrence; Richard A Brigandi; Federico M Gomez-delas-Heras; Domingo V Gargallo; Stephen A Ward
Candidate selection and preclinical evaluation of N-tert-butyl isoquine (GSK369796), an affordable and effective 4-aminoquinoline antimalarial for the 21st century.
Journal of medicinal chemistry 2009;52(5):1408-15.
2009: David J Bell; Dan Wootton; Mavuto Mukaka; Jacqui Montgomery; Noel Kayange; Phillips Chimpeni; Dyfrig A Hughes; Malcolm E Molyneux; Steve A Ward; Peter A Winstanley; David Lalloo
Measurement of adherence, drug concentrations and the effectiveness of artemether-lumefantrine, chlorproguanil-dapsone or sulphadoxine-pyrimethamine in the treatment of uncomplicated malaria in Malawi.
Malaria journal 2009;8():204.
2009: Zul Premji; Rich E Umeh; Seth Owusu-Agyei; Fabian Esamai; Emmanuel U Ezedinachi; Stephen Oguche; Steffen Borrmann; Akintunde Sowunmi; Stephan Duparc; Paula L Kirby; Allan Pamba; Lynda Kellam; Robert Guiguemdé; Brian Greenwood; Stephen A Ward; Peter A Winstanley
Chlorproguanil-dapsone-artesunate versus artemether-lumefantrine: a randomized, double-blind phase III trial in African children and adolescents with uncomplicated Plasmodium falciparum malaria.
PloS one 2009;4(8):e6682.
2008: Edwin Ochong; David J Bell; David J Johnson; Umberto D'Alessandro; Modest Mulenga; Sant Muangnoicharoen; Jean-Pierre Van geertruyden; Peter A Winstanley; Patrick G Bray; Stephen A Ward; Andrew Owen
Plasmodium falciparum strains harboring dihydrofolate reductase with the I164L mutation are absent in Malawi and Zambia even under antifolate drug pressure.
Antimicrobial agents and chemotherapy 2008;52(11):3883-8.
2008: Daniel G Wootton; Hyginus Opara; Giancarlo A Biagini; Maxwell K Kanjala; Stephan Duparc; Paula L Kirby; Mary Woessner; Colin Neate; Maggie Nyirenda; Hannah Blencowe; Queen Dube-Mbeye; Thomas Kanyok; Stephen Ward; Malcolm E Molyneux; Sam Dunyo; Peter A Winstanley
Open-label comparative clinical study of chlorproguanil-dapsone fixed dose combination (Lapdap) alone or with three different doses of artesunate for uncomplicated Plasmodium falciparum malaria.
PloS one 2008;3(3):e1779.
2007: Abdinasir A Amin; Tom Walley; Gilbert O Kokwaro; Peter A Winstanley; Robert W Snow
Reconciling national treatment policies and drug regulation in Kenya.
Health policy and planning 2007;22(2):111-2.
2006: Trudie Lang; Dyfrig Hughes; Tom Kanyok; Jane F Kengeya-Kayondo; Vicki Marsh; Ane Haaland; Munir Pirmohamed; Peter A Winstanley
Beyond registration--measuring the public-health potential of new treatments for malaria in Africa.
The Lancet infectious diseases 2006;6(1):46-52.
2005: Alexis Nzila; Edwin O Ochong; Eunice Nduati; Kokwaro Gilbert; Peter A Winstanley; Steve Ward; Kevin Marsh
Why has the dihydrofolate reductase 164 mutation not consistently been found in Africa yet?
Transactions of the Royal Society of Tropical Medicine and Hygiene 2005;99(5):341-6.
2004: Sarah J Bates; Peter A Winstanley; William M Watkins; Ali Alloueche; Juma Bwika; T Christian Happi; Song Le; James Kublin; Zul Premji; Carol Hopkins Sibley
Rare, highly pyrimethamine-resistant alleles of the Plasmodium falciparum dihydrofolate reductase gene from 5 African sites.
The Journal of infectious diseases 2004;190(10):1783-92.
2004: Abdinasir A Amin; Dyfrig A Hughes; Vicki Marsh; Timothy O Abuya; Gilbert O Kokwaro; Peter A Winstanley; Sam A Ochola; Robert W Snow
The difference between effectiveness and efficacy of antimalarial drugs in Kenya.
Tropical medicine & international health : TM & IH 2004;9(9):967-74.
2004: Ali Alloueche; W Bailey; S Barton; J Bwika; Phillips Chimpeni; Catherine O Falade; Fatai A Fehintola; Richard John Horton; Shabbar Jaffar; Thomas P Kanyok; Song Le; James Kublin; T Lang; Michel A Missinou; C Mkandala; Ayoade Oduola; Zul Premji; L Robertson; Akintunde Sowunmi; S A Ward; Peter A Winstanley
Comparison of chlorproguanil-dapsone with sulfadoxine-pyrimethamine for the treatment of uncomplicated falciparum malaria in young African children: double-blind randomised controlled trial.
Lancet 2004;363(9424):1843-8.
2004: Alexis Nzila; Gilbert O Kokwaro; Peter A Winstanley; Kevin Marsh; Stephen A Ward
Therapeutic potential of folate uptake inhibition in Plasmodium falciparum.
Trends in parasitology 2004;20(3):109-12.
2004: David Bell; Peter A Winstanley
Current issues in the treatment of uncomplicated malaria in Africa.
British medical bulletin 2004;71():29-43.
2003: Paul M O'Neill; Amira Mukhtar; Paul A Stocks; Laura E Randle; Stephen Hindley; Stephen A Ward; Richard C Storr; Jamie F Bickley; Ian A O'Neil; James L Maggs; Ruth H Hughes; Peter A Winstanley; Patrick G Bray; B Kevin Park
Isoquine and related amodiaquine analogues: a new generation of improved 4-aminoquinoline antimalarials.
Journal of medicinal chemistry 2003;46(23):4933-45.
2003: Alexis Nzila; Edward K Mberu; Pat Bray; Gilbert O Kokwaro; Peter A Winstanley; Kevin Marsh; Steve Ward
Chemosensitization of Plasmodium falciparum by probenecid in vitro.
Antimicrobial agents and chemotherapy 2003;47(7):2108-12.
2003: Jonathan Lochhead; Armand Movaffaghy; Benedetto Falsini; Peter A Winstanley; Edward K Mberu; Charles E Riva; Malcolm E Molyneux; Terrie E Taylor; Simon P Harding
The effect of quinine on the electroretinograms of children with pediatric cerebral malaria.
The Journal of infectious diseases 2003;187(8):1342-5.
2002: Peter A Winstanley
Coping with malaria in the face of resistance.
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 2002;6(4):246-52.
2002: J Sulo; Phillips Chimpeni; J Hatcher; James Kublin; Christopher Plowe; Malcolm E Molyneux; K Marsh; Terrie E Taylor; William M Watkins; Peter A Winstanley
Chlorproguanil-dapsone versus sulfadoxine-pyrimethamine for sequential episodes of uncomplicated falciparum malaria in Kenya and Malawi: a randomised clinical trial.
Lancet 2002;360(9340):1136-43.
2002: Peter A Winstanley; Steven A Ward; Robert W Snow
Clinical status and implications of antimalarial drug resistance.
Microbes and infection / Institut Pasteur 2002;4(2):157-64.
2002: James Kublin; Fraction K Dzinjalamala; Deborah D Kamwendo; Elissa Malkin; Joseph F Cortese; Lisa M Martino; Rabia A G Mukadam; Stephen J Rogerson; Andres Lescano; Malcolm E Molyneux; Peter A Winstanley; Phillips Chimpeni; Terrie E Taylor; Christopher Plowe
Molecular markers for failure of sulfadoxine-pyrimethamine and chlorproguanil-dapsone treatment of Plasmodium falciparum malaria.
The Journal of infectious diseases 2002;185(3):380-8.
2001: Carol Hopkins Sibley; John E Hyde; Paul F G Sims; Christopher Plowe; James Kublin; Edward K Mberu; A F Cowman; Peter A Winstanley; William M Watkins; Alexis Nzila
Pyrimethamine-sulfadoxine resistance in Plasmodium falciparum: what next?
Trends in parasitology 2001;17(12):582-8.
2001: Peter A Winstanley
Modern chemotherapeutic options for malaria.
The Lancet infectious diseases 2001;1(4):242-50.
2001: Peter A Winstanley
Chlorproguanil-dapsone (LAPDAP) for uncomplicated falciparum malaria.
Tropical medicine & international health : TM & IH 2001;6(11):952-4.
2001: Theonest K Mutabingwa; Alexis Nzila; Edward K Mberu; Eunice Nduati; Peter A Winstanley; E Hills; William Watkins
Chlorproguanil-dapsone for treatment of drug-resistant falciparum malaria in Tanzania.
Lancet 2001;358(9289):1218-23.
2000: Alexis Nzila; Eunice Nduati; Edward K Mberu; C Hopkins Sibley; S A Monks; Peter A Winstanley; William M Watkins
Molecular evidence of greater selective pressure for drug resistance exerted by the long-acting antifolate Pyrimethamine/Sulfadoxine compared with the shorter-acting chlorproguanil/dapsone on Kenyan Plasmodium falciparum.
The Journal of infectious diseases 2000;181(6):2023-8.
2000: D S Almond; I S Szwandt; G Edwards; M G Lee; Peter A Winstanley
Disposition of intravenous pyrimethamine in healthy volunteers.
Antimicrobial agents and chemotherapy 2000;44(6):1691-3.
2000: Peter A Winstanley
Chemotherapy for falciparum malaria: the armoury, the problems and the prospects.
Parasitology today (Personal ed.) 2000;16(4):146-53.
2000: Alexis Nzila; Edward K Mberu; J Sulo; H Dayo; Peter A Winstanley; Carol Hopkins Sibley; William M Watkins
Towards an understanding of the mechanism of pyrimethamine-sulfadoxine resistance in Plasmodium falciparum: genotyping of dihydrofolate reductase and dihydropteroate synthase of Kenyan parasites.
Antimicrobial agents and chemotherapy 2000;44(4):991-6.
2000: Jane Crawley; Catherine Waruiru; Sadik Mithwani; Isaiah Mwangi; William Watkins; D Ouma; Peter A Winstanley; T E A Peto; Kevin Marsh
Effect of phenobarbital on seizure frequency and mortality in childhood cerebral malaria: a randomised, controlled intervention study.
Lancet 2000;355(9205):701-6.
2000: James L Maggs; Laurence P D Bishop; Geoffrey Edwards; Paul M O'Neill; Stephen A Ward; Peter A Winstanley; B Kevin Park
Biliary metabolites of beta-artemether in rats: biotransformations of an antimalarial endoperoxide.
Drug metabolism and disposition: the biological fate of chemicals 2000;28(2):209-17.
1999: Samson Kinyanjui; Edward K Mberu; Peter A Winstanley; D P Jacobus; William M Watkins
The antimalarial triazine WR99210 and the prodrug PS-15: folate reversal of in vitro activity against Plasmodium falciparum and a non-antifolate mode of action of the prodrug.
The American journal of tropical medicine and hygiene 1999;60(6):943-7.
1999: William M Watkins; Edward K Mberu; Peter A Winstanley; Christopher Plowe
More on 'the efficacy of antifolate antimalarial combinations in Africa'.
Parasitology today (Personal ed.) 1999;15(4):131-2.
1998: Peter A Winstanley
Albendazole for mass treatment of asymptomatic trichuris infections.
Lancet 1998;352(9134):1080-1.
1998: Peter A Winstanley
Malaria: treatment.
Journal of the Royal College of Physicians of London 1998;32(3):203-7.
1998: K Haruki; Peter A Winstanley; William M Watkins; Kevin Marsh
Quinine sensitivity of isolates of Plasmodium falciparum from the coast of Kenya.
Transactions of the Royal Society of Tropical Medicine and Hygiene 1998;92(2):195-6.
1998: A Nzila-Mounda; Edward K Mberu; Carol Hopkins Sibley; Christopher Plowe; Peter A Winstanley; William M Watkins
Kenyan Plasmodium falciparum field isolates: correlation between pyrimethamine and chlorcycloguanil activity in vitro and point mutations in the dihydrofolate reductase domain.
Antimicrobial agents and chemotherapy 1998;42(1):164-9.
1997: William M Watkins; Edward K Mberu; Peter A Winstanley; Christopher Plowe
The efficacy of antifolate antimalarial combinations in Africa: a predictive model based on pharmacodynamic and pharmacokinetic analyses.
Parasitology today (Personal ed.) 1997;13(12):459-64.
1997: Christopher Plowe; Joseph F Cortese; Abdoulaye A Djimde; Okey C Nwanyanwu; William M Watkins; Peter A Winstanley; J G Estrada-Franco; René Mollinedo; Juan Carlos Avila; J L Cespedes; D Carter; Ogobara K Doumbo
Mutations in Plasmodium falciparum dihydrofolate reductase and dihydropteroate synthase and epidemiologic patterns of pyrimethamine-sulfadoxine use and resistance.
The Journal of infectious diseases 1997;176(6):1590-6.
1997: Alasdair M Breckenridge; Peter A Winstanley
Clinical pharmacology and malaria.
Annals of tropical medicine and parasitology 1997;91(7):727-33.
1997: E Amukoye; Peter A Winstanley; William M Watkins; R W Snow; J Hatcher; Moses Mosobo; E Ngumbao; B Lowe; M Ton; G Minyiri; Kevin Marsh
Chlorproguanil-dapsone: effective treatment for uncomplicated falciparum malaria.
Antimicrobial agents and chemotherapy 1997;41(10):2261-4.
1997: M Hero; Simon P Harding; Charles E Riva; Peter A Winstanley; Norbert Peshu; K Marsh
Photographic and angiographic characterization of the retina of Kenyan children with severe malaria.
Archives of ophthalmology 1997;115(8):997-1003.
1997: S A Murphy; Edward K Mberu; D Muhia; Mike English; Jane Crawley; Catherine Waruiru; Brett Lowe; Charles Newton; Peter A Winstanley; Kevin Marsh; William M Watkins
The disposition of intramuscular artemether in children with cerebral malaria; a preliminary study.
Transactions of the Royal Society of Tropical Medicine and Hygiene 1997;91(3):331-4.
1997: Peter A Winstanley; William Watkins; D Muhia; S Szwandt; E Amukoye; Kevin Marsh
Chlorproguanil/dapsone for uncomplicated Plasmodium falciparum malaria in young children: pharmacokinetics and therapeutic range.
Transactions of the Royal Society of Tropical Medicine and Hygiene 1997;91(3):322-7.
1997: Charles Newton; T Chokwe; J A Schellenberg; Peter A Winstanley; D Forster; Norbert Peshu; FJ Kirkham; Kevin Marsh
Coma scales for children with severe falciparum malaria.
Transactions of the Royal Society of Tropical Medicine and Hygiene 1997;91(2):161-5.
1997: Charles Newton; Jane Crawley; A Sowumni; Catherine Waruiru; Isaiah Mwangi; Mike English; S Murphy; Peter A Winstanley; Kevin Marsh; FJ Kirkham
Intracranial hypertension in Africans with cerebral malaria.
Archives of disease in childhood 1997;76(3):219-26.
1997: Charles Newton; PA Warn; Peter A Winstanley; Norbert Peshu; Robert W Snow; G Pasvol; Kevin Marsh
Severe anaemia in children living in a malaria endemic area of Kenya.
Tropical medicine & international health : TM & IH 1997;2(2):165-78.
1997: Gilbert O Kokwaro; G Edwards; P Roberts; S Ward; Peter A Winstanley; William Watkins
Infection with Plasmodium berghei alters benzodiazepine receptor in rat brain.
Archives of medical research 1997;28(3):425-7.
1996: Peter A Winstanley
Mefloquine: the benefits outweigh the risks.
British journal of clinical pharmacology 1996;42(4):411-3.
1996: S Murphy; Mike English; Catherine Waruiru; Isaiah Mwangi; E Amukoye; Jane Crawley; C Newton; Peter A Winstanley; Norbert Peshu; Kevin Marsh
An open randomized trial of artemether versus quinine in the treatment of cerebral malaria in African children.
Transactions of the Royal Society of Tropical Medicine and Hygiene 1996;90(3):298-301.
1996: Catherine Waruiru; Charles Newton; D Forster; L New; Peter A Winstanley; Isaiah Mwangi; V Marsh; M Winstanley; Robert W Snow; Kevin Marsh
Epileptic seizures and malaria in Kenyan children.
Transactions of the Royal Society of Tropical Medicine and Hygiene 1996;90(2):152-5.
1996: William M Watkins; M Mungai; D K Muhia; Edward K Mberu; S Gathua; Peter A Winstanley; C F Gilks; P Nunn
Cutaneous hypersensitivity reactions to thiacetazone, HIV infection and thiacetazone concentrations in plasma.
British journal of clinical pharmacology 1996;41(2):160-2.
1996: Peter A Winstanley
Pyronaridine: a promising drug for Africa?
Lancet 1996;347(8993):2-3.
1995: S Murphy; William M Watkins; P G Bray; Brett Lowe; Peter A Winstanley; Norbert Peshu; Kevin Marsh
Parasite viability during treatment of severe falciparum malaria: differential effects of artemether and quinine.
The American journal of tropical medicine and hygiene 1995;53(3):303-5.
1995: Peter A Winstanley; S Khoo; S Szwandt; Geoffrey Edwards; E Wilkins; J Tija; R Coker; W McKane; N Beeching; S Watkin
Marked variation in pyrimethamine disposition in AIDS patients treated for cerebral toxoplasmosis.
The Journal of antimicrobial chemotherapy 1995;36(2):435-9.
1995: Peter A Winstanley
Drug treatment of toxoplasmic encephalitis in acquired immunodeficiency syndrome.
Postgraduate medical journal 1995;71(837):404-8.
1995: Kevin Marsh; D Forster; Catherine Waruiru; Isaiah Mwangi; M Winstanley; V Marsh; C Newton; Peter A Winstanley; P Warn; Norbert Peshu
Indicators of life-threatening malaria in African children.
The New England journal of medicine 1995;332(21):1399-404.
1995: Peter A Winstanley; Edward K Mberu; I S Szwandt; Alasdair M Breckenridge; William M Watkins
In vitro activities of novel antifolate drug combinations against Plasmodium falciparum and human granulocyte CFUs.
Antimicrobial agents and chemotherapy 1995;39(4):948-52.
1995: William M Watkins; Peter A Winstanley; Edward K Mberu; G Kokwaro; S A Murphy; C J Newton; Isaiah Mwangi; D Forster; Kevin Marsh
Halofantrine pharmacokinetics in Kenyan children with non-severe and severe malaria.
British journal of clinical pharmacology 1995;39(3):283-7.
1994: Peter A Winstanley; Edward K Mberu; William M Watkins; S A Murphy; Brett Lowe; Kevin Marsh
Towards optimal regimens of parenteral quinine for young African children with cerebral malaria: unbound quinine concentrations following a simple loading dose regimen.
Transactions of the Royal Society of Tropical Medicine and Hygiene 1994;88(5):577-80.
1994: Geoffrey Edwards; Peter A Winstanley; Stephen A Ward
Clinical pharmacokinetics in the treatment of tropical diseases. Some applications and limitations.
Clinical pharmacokinetics 1994;27(2):150-65.
1993: P Nunn; J Porter; Peter A Winstanley
Thiacetazone--avoid like poison or use with care?
Transactions of the Royal Society of Tropical Medicine and Hygiene 1993;87(5):578-82.
1993: Robert W Snow; J R Schellenberg; Norbert Peshu; D Forster; Charles Newton; Peter A Winstanley; Isaiah Mwangi; Catherine Waruiru; P A Warn; Chris Newbold
Periodicity and space-time clustering of severe childhood malaria on the coast of Kenya.
Transactions of the Royal Society of Tropical Medicine and Hygiene 1993;87(4):386-90.
1993: Charles Newton; Peter A Winstanley; William M Watkins; Isaiah Mwangi; Catherine Waruiru; Edward K Mberu; P A Warn; C G Nevill; Kevin Marsh
A single dose of intramuscular sulfadoxine-pyrimethamine as an adjunct to quinine in the treatment of severe malaria: pharmacokinetics and efficacy.
Transactions of the Royal Society of Tropical Medicine and Hygiene 1993;87(2):207-10.
1993: Peter A Winstanley; C Newton; William Watkins; Edward K Mberu; S Ward; P Warn; Isaiah Mwangi; Catherine Waruiru; G Pasvol; D Warrell
Towards optimal regimens of parenteral quinine for young African children with cerebral malaria: the importance of unbound quinine concentration.
Transactions of the Royal Society of Tropical Medicine and Hygiene 1993;87(2):201-6.
1992: Peter A Winstanley
Treatment and prevention of falciparum malaria in Africa.
Journal of the Royal College of Physicians of London 1992;26(4):445-9.
1992: Robert W Snow; J R Armstrong; D Forster; M T Winstanley; V M Marsh; Charles Newton; Catherine Waruiru; Isaiah Mwangi; Peter A Winstanley; Kevin Marsh
Childhood deaths in Africa: uses and limitations of verbal autopsies.
Lancet 1992;340(8815):351-5.
1992: Peter A Winstanley; Charles Newton; G Pasvol; F J Kirkham; Edward K Mberu; Norbert Peshu; Stephen A Ward; J B Were; D A Warrell; Kevin Marsh
Prophylactic phenobarbitone in young children with severe falciparum malaria: pharmacokinetics and clinical effects.
British journal of clinical pharmacology 1992;33(2):149-54.
1992: Peter A Winstanley; William M Watkins; Charles Newton; C Nevill; Edward K Mberu; P A Warn; Catherine Waruiru; Isaiah Mwangi; D A Warrell; Kevin Marsh
The disposition of oral and intramuscular pyrimethamine/sulphadoxine in Kenyan children with high parasitaemia but clinically non-severe falciparum malaria.
British journal of clinical pharmacology 1992;33(2):143-8.
1991: Edward K Mberu; Stephen A Ward; Peter A Winstanley; William M Watkins
Measurement of quinine in filter paper-absorbed blood by high-performance liquid chromatography.
Journal of chromatography 1991;570(1):180-4.
1991: Charles Newton; F J Kirkham; Peter A Winstanley; G Pasvol; Norbert Peshu; D A Warrell; Kevin Marsh
Intracranial pressure in African children with cerebral malaria.
Lancet 1991;337(8741):573-6.
1990: Peter A Winstanley; O Simooya; J M Kofi-Ekue; O Walker; Lateef A Salako; Geoffrey Edwards; M L Orme; Alasdair M Breckenridge
The disposition of amodiaquine in Zambians and Nigerians with malaria.
British journal of clinical pharmacology 1990;29(6):695-701.
1990: Peter A Winstanley; John W Coleman; James L Maggs; Alasdair M Breckenridge; B Kevin Park
The toxicity of amodiaquine and its principal metabolites towards mononuclear leucocytes and granulocyte/monocyte colony forming units.
British journal of clinical pharmacology 1990;29(4):479-85.
1990: Tom Walley; Peter A Winstanley; D Roberts; M Grimmer; M Orme; A Breckenridge
Adverse effects of captopril in hospital outpatients with hypertension.
Postgraduate medical journal 1990;66(772):106-9.
1989: Peter A Winstanley; M L Orme
The effects of food on drug bioavailability.
British journal of clinical pharmacology 1989;28(6):621-8.
1988: Peter A Winstanley; Geoffrey Edwards; C G Curtis; M L Orme; G M Powell; Alasdair M Breckenridge
Tissue distribution and excretion of amodiaquine in the rat.
The Journal of pharmacy and pharmacology 1988;40(5):343-9.
1987: Peter A Winstanley; Alasdair M Breckenridge
Currently important antimalarial drugs.
Annals of tropical medicine and parasitology 1987;81(5):619-27.
1987: Peter A Winstanley; G Edwards; M Orme; A Breckenridge
The disposition of amodiaquine in man after oral administration.
British journal of clinical pharmacology 1987;23(1):1-7.