Christine Winterbourn

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Nagy Péter; Jameson Guy N L; Winterbourn Christine C
Kinetics and mechanisms of the reaction of hypothiocyanous acid with 5-thio-2-nitrobenzoic acid and reduced glutathione.
Brown Kristin K; Blaikie Frances H; Smith Robin A J; Tyndall Joel D A; Lue Hongqi; Bernhagen Jürgen; Winterbourn Christine C; Hampton Mark B
Direct modification of the proinflammatory cytokine macrophage migration inhibitory factor by dietary isothiocyanates.
Stacey Melissa M; Peskin Alexander V; Vissers Margreet C; Winterbourn Christine C
Chloramines and hypochlorous acid oxidize erythrocyte peroxiredoxin 2.

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All Publications

2009: Nagy Péter; Jameson Guy N L; Winterbourn Christine C
Kinetics and mechanisms of the reaction of hypothiocyanous acid with 5-thio-2-nitrobenzoic acid and reduced glutathione.
Chemical research in toxicology 2009;22(11):1833-40.
2009: Brown Kristin K; Blaikie Frances H; Smith Robin A J; Tyndall Joel D A; Lue Hongqi; Bernhagen Jürgen; Winterbourn Christine C; Hampton Mark B
Direct modification of the proinflammatory cytokine macrophage migration inhibitory factor by dietary isothiocyanates.
The Journal of biological chemistry 2009;284(47):32425-33.
2009: Stacey Melissa M; Peskin Alexander V; Vissers Margreet C; Winterbourn Christine C
Chloramines and hypochlorous acid oxidize erythrocyte peroxiredoxin 2.
Free radical biology & medicine 2009;47(10):1468-76.
2009: Peskin Alexander V; Turner Rufus; Maghzal Ghassan J; Winterbourn Christine C; Kettle Anthony J
Oxidation of methionine to dehydromethionine by reactive halogen species generated by neutrophils.
Biochemistry 2009;48(42):10175-82.
2009: Harwood D Tim; Kettle Anthony J; Brennan Siobhain; Winterbourn Christine C
Simultaneous determination of reduced glutathione, glutathione disulphide and glutathione sulphonamide in cells and physiological fluids by isotope dilution liquid chromatography-tandem mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2009;877(28):3393-9.
2009: Cox Andrew G; Peskin Alexander V; Paton Louise N; Winterbourn Christine C; Hampton Mark B
Redox potential and peroxide reactivity of human peroxiredoxin 3.
Biochemistry 2009;48(27):6495-501.
2009: Cox Andrew G; Pearson Andree G; Pullar Juliet M; Jönsson Thomas J; Lowther W Todd; Winterbourn Christine C; Hampton Mark B
Mitochondrial peroxiredoxin 3 is more resilient to hyperoxidation than cytoplasmic peroxiredoxins.
The Biochemical journal 2009;421(1):51-8.
2009: Nagy Péter; Kettle Anthony J; Winterbourn Christine C
Superoxide-mediated formation of tyrosine hydroperoxides and methionine sulfoxide in peptides through radical addition and intramolecular oxygen transfer.
The Journal of biological chemistry 2009;284(22):14723-33.
2009: Kumar Vikas; Kitaeff Nailya; Hampton Mark B; Cannell Mark B; Winterbourn Christine C
Reversible oxidation of mitochondrial peroxiredoxin 3 in mouse heart subjected to ischemia and reperfusion.
FEBS letters 2009;583(6):997-1000.
2009: Palmer Barry R; Devereaux Courtney L; Dhamrait Sukhbir S; Mocatta Tessa J; Pilbrow Anna P; Frampton Chris M; Skelton Lorraine; Yandle Tim G; Winterbourn Christine C; Richards A Mark; Montgomery Hugh E; Cameron Vicky A
The common G-866A polymorphism of the UCP2 gene and survival in diabetic patients following myocardial infarction.
Cardiovascular diabetology 2009;8():31.
2009: Cuddihy Sarah L; Baty James W; Brown Kristin K; Winterbourn Christine C; Hampton Mark B
Proteomic detection of oxidized and reduced thiol proteins in cultured cells.
Methods in molecular biology (Clifton, N.J.) 2009;519():363-75.
2008: Winterbourn Christine C; Hampton Mark B
Thiol chemistry and specificity in redox signaling.
Free radical biology & medicine 2008;45(5):549-61.
2008: Low Felicia M; Hampton Mark B; Winterbourn Christine C
Peroxiredoxin 2 and peroxide metabolism in the erythrocyte.
Antioxidants & redox signaling 2008;10(9):1621-30.
2008: Harwood D Tim; Nimmo Susan L; Kettle Anthony J; Winterbourn Christine C; Ashby Michael T
Molecular structure and dynamic properties of a sulfonamide derivative of glutathione that is produced under conditions of oxidative stress by hypochlorous acid.
Chemical research in toxicology 2008;21(5):1011-6.
2008: Winterbourn Christine C
Reconciling the chemistry and biology of reactive oxygen species.
Nature chemical biology 2008;4(5):278-86.
2008: Cuddihy Sarah L; Parker Amber; Harwood D Tim; Vissers Margreet C M; Winterbourn Christine C
Ascorbate interacts with reduced glutathione to scavenge phenoxyl radicals in HL60 cells.
Free radical biology & medicine 2008;44(8):1637-44.
2007: Akerström Bo; Maghzal Ghassan J; Winterbourn Christine C; Kettle Anthony J
The lipocalin alpha1-microglobulin has radical scavenging activity.
The Journal of biological chemistry 2007;282(43):31493-503.
2007: Mocatta Tessa J; Pilbrow Anna P; Cameron Vicky A; Senthilmohan Revathy; Frampton Chris M; Richards A Mark; Winterbourn Christine C
Plasma concentrations of myeloperoxidase predict mortality after myocardial infarction.
Journal of the American College of Cardiology 2007;49(20):1993-2000.
2007: Kettle Anthony J; Anderson Robert F; Hampton Mark B; Winterbourn Christine C
Reactions of superoxide with myeloperoxidase.
Biochemistry 2007;46(16):4888-97.
2007: Peskin Alexander V; Low Felicia M; Paton Louise N; Maghzal Ghassan J; Hampton Mark B; Winterbourn Christine C
The high reactivity of peroxiredoxin 2 with H(2)O(2) is not reflected in its reaction with other oxidants and thiol reagents.
The Journal of biological chemistry 2007;282(16):11885-92.
2007: Low Felicia M; Hampton Mark B; Peskin Alexander V; Winterbourn Christine C
Peroxiredoxin 2 functions as a noncatalytic scavenger of low-level hydrogen peroxide in the erythrocyte.
Blood 2007;109(6):2611-7.
2007: Green Jessie N; Winterbourn Christine C; Hampton Mark B
Analysis of neutrophil bactericidal activity.
Methods in molecular biology (Clifton, N.J.) 2007;412():319-32.
2006: Winterbourn Christine C; Hampton Mark B; Livesey John H; Kettle Anthony J
Modeling the reactions of superoxide and myeloperoxidase in the neutrophil phagosome: implications for microbial killing.
The Journal of biological chemistry 2006;281(52):39860-9.
2006: Harwood D Tim; Kettle Anthony J; Winterbourn Christine C
Production of glutathione sulfonamide and dehydroglutathione from GSH by myeloperoxidase-derived oxidants and detection using a novel LC-MS/MS method.
The Biochemical journal 2006;399(1):161-8.
2006: Cameron Vicky A; Mocatta Tessa J; Pilbrow Anna P; Frampton Chris M; Troughton Richard W; Richards A Mark; Winterbourn Christine C
Angiotensin type-1 receptor A1166C gene polymorphism correlates with oxidative stress levels in human heart failure.
Hypertension 2006;47(6):1155-61.
2006: Midwinter Robyn G; Cheah Fook-Choe; Moskovitz Jackob; Vissers Margret C; Winterbourn Christine C
IkappaB is a sensitive target for oxidation by cell-permeable chloramines: inhibition of NF-kappaB activity by glycine chloramine through methionine oxidation.
The Biochemical journal 2006;396(1):71-8.
2006: Cheah F-C; Darlow B A; Winterbourn C C
Association of hydrogen peroxide in exhaled breath condensates from infants with respiratory distress syndrome with the development of chronic lung disease.
Archives of disease in childhood. Fetal and neonatal edition 2006;91(2):F155.
2006: van Dalen Christine J; Winterbourn Christine C; Kettle Anthony J
Mechanism of nitrite oxidation by eosinophil peroxidase: implications for oxidant production and nitration by eosinophils.
The Biochemical journal 2006;394(Pt 3):707-13.
2006: Peskin Alexander V; Winterbourn Christine C
Taurine chloramine is more selective than hypochlorous acid at targeting critical cysteines and inactivating creatine kinase and glyceraldehyde-3-phosphate dehydrogenase.
Free radical biology & medicine 2006;40(1):45-53.
2005: Baty James W; Hampton Mark B; Winterbourn Christine C
Proteomic detection of hydrogen peroxide-sensitive thiol proteins in Jurkat cells.
The Biochemical journal 2005;389(Pt 3):785-95.
2005: Kalogerakis George; Baker Arthur M; Christov Steve; Rowley Kevin G; Dwyer Karen; Winterbourn Christine; Best James D; Jenkins Alicia J
Oxidative stress and high-density lipoprotein function in Type I diabetes and end-stage renal disease.
Clinical science (London, England : 1979) 2005;108(6):497-506.
2005: Cheah Fook-Choe; Winterbourn Christine C; Darlow Brian A; Mocatta Tessa J; Vissers Margret C M
Nuclear factor kappaB activation in pulmonary leukocytes from infants with hyaline membrane disease: associations with chorioamnionitis and Ureaplasma urealyticum colonization.
Pediatric research 2005;57(5 Pt 1):616-23.
2005: Darlow B A; Buss H; McGill F; Fletcher L; Graham P; Winterbourn C C
Vitamin C supplementation in very preterm infants: a randomised controlled trial.
Archives of disease in childhood. Fetal and neonatal edition 2005;90(2):F117-22.
2005: Cheah Fook-Choe; Hampton Mark B; Darlow Brian A; Winterbourn Christine C; Vissers Margret C M
Detection of apoptosis by caspase-3 activation in tracheal aspirate neutrophils from premature infants: relationship with NF-kappaB activation.
Journal of leukocyte biology 2005;77(3):432-7.
2005: Peskin Alexander V; Midwinter Robyn G; Harwood David T; Winterbourn Christine C
Chlorine transfer between glycine, taurine, and histamine: reaction rates and impact on cellular reactivity.
Free radical biology & medicine 2005;38(3):397-405.
2005: Ellison Vanessa J; Mocatta Tessa J; Winterbourn Christine C; Darlow Brian A; Volpe Joseph J; Inder Terrie E
The relationship of CSF and plasma cytokine levels to cerebral white matter injury in the premature newborn.
Pediatric research 2005;57(2):282-6.
2005: Kettle Anthony J; Winterbourn Christine C
Do neutrophils produce ozone? An appraisal of current evidence.
BioFactors (Oxford, England) 2005;24(1-4):41-5.
2004: Peskin Alexander V; Midwinter Robyn G; Harwood David T; Winterbourn Christine C
Chlorine transfer between glycine, taurine, and histamine: reaction rates and impact on cellular reactivity.
Free radical biology & medicine 2004;37(10):1622-30.
2004: Winterbourn Christine C; Kettle Anthony J
Reactions of superoxide with myeloperoxidase and its products.
Japanese journal of infectious diseases 2004;57(5):S31-3.
2004: Midwinter Robyn G; Peskin Alexander V; Vissers Margret C M; Winterbourn Christine C
Extracellular oxidation by taurine chloramine activates ERK via the epidermal growth factor receptor.
The Journal of biological chemistry 2004;279(31):32205-11.
2004: Winterbourn Christine C; Parsons-Mair Helena N; Gebicki Silvia; Gebicki Janusz M; Davies Michael J
Requirements for superoxide-dependent tyrosine hydroperoxide formation in peptides.
The Biochemical journal 2004;381(Pt 1):241-8.
2004: Kettle Anthony J; Clark Bruce M; Winterbourn Christine C
Superoxide converts indigo carmine to isatin sulfonic acid: implications for the hypothesis that neutrophils produce ozone.
The Journal of biological chemistry 2004;279(18):18521-5.
2004: Munday Rex; Munday Christine M; Winterbourn Christine C
Inhibition of copper-catalyzed cysteine oxidation by nanomolar concentrations of iron salts.
Free radical biology & medicine 2004;36(6):757-64.
2004: Mocatta Tessa J; Winterbourn Christine C; Inder Terrie E; Darlow Brian A
The effect of gestational age and labour on markers of lipid and protein oxidation in cord plasma.
Free radical research 2004;38(2):185-91.
2003: Peskin Alexander V; Winterbourn Christine C
Histamine chloramine reactivity with thiol compounds, ascorbate, and methionine and with intracellular glutathione.
Free radical biology & medicine 2003;35(10):1252-60.
2003: Chapman Anna L P; Winterbourn Christine C; Brennan Stephen O; Jordan T William; Kettle Anthony J
Characterization of non-covalent oligomers of proteins treated with hypochlorous acid.
The Biochemical journal 2003;375(Pt 1):33-40.
2003: Winterbourn Christine C; Kettle Anthony J
Radical-radical reactions of superoxide: a potential route to toxicity.
Biochemical and biophysical research communications 2003;305(3):729-36.
2003: Buss I Hendrikje; Senthilmohan Revathy; Darlow Brian A; Mogridge Nina; Kettle Anthony J; Winterbourn Christine C
3-Chlorotyrosine as a marker of protein damage by myeloperoxidase in tracheal aspirates from preterm infants: association with adverse respiratory outcome.
Pediatric research 2003;53(3):455-62.
2003: Cheah Fook-Choe; Darlow Brian A; Winterbourn Christine C
Problems associated with collecting breath condensate for the measurement of exhaled hydrogen peroxide from neonates on respiratory support.
Biology of the neonate 2003;84(4):338-41.
2003: Winterbourn Christine C; Bonham Martin J D; Buss Hendrikje; Abu-Zidan Fikri M; Windsor John A
Elevated protein carbonyls as plasma markers of oxidative stress in acute pancreatitis.
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2003;3(5):375-82.
2002: Winterbourn Christine C
Biological reactivity and biomarkers of the neutrophil oxidant, hypochlorous acid.
Toxicology 2002;181-182():223-7.
2002: Baty James W; Hampton Mark B; Winterbourn Christine C
Detection of oxidant sensitive thiol proteins by fluorescence labeling and two-dimensional electrophoresis.
Proteomics 2002;2(9):1261-6.
2002: Inder Terrie; Mocatta Tessa; Darlow Brian; Spencer Carole; Volpe Joseph J; Winterbourn Christine
Elevated free radical products in the cerebrospinal fluid of VLBW infants with cerebral white matter injury.
Pediatric research 2002;52(2):213-8.
2002: Inder Terrie; Mocatta Tessa; Darlow Brian; Spencer Carole; Senthilmohan Revathy; Winterbourn Christine C; Volpe Joseph J
Markers of oxidative injury in the cerebrospinal fluid of a premature infant with meningitis and periventricular leukomalacia.
The Journal of pediatrics 2002;140(5):617-21.
2002: Hampton Mark B; Vissers Margret C M; Keenan Jacqueline I; Winterbourn Christine C
Oxidant-mediated phosphatidylserine exposure and macrophage uptake of activated neutrophils: possible impairment in chronic granulomatous disease.
Journal of leukocyte biology 2002;71(5):775-81.
2002: Hampton Mark B; Stamenkovic Ivan; Winterbourn Christine C
Interaction with substrate sensitises caspase-3 to inactivation by hydrogen peroxide.
FEBS letters 2002;517(1-3):229-32.
2002: Roos Dirk; Winterbourn Christine C
Immunology. Lethal weapons.
Science (New York, N.Y.) 2002;296(5568):669-71.
2002: Chapman Anna L P; Hampton Mark B; Senthilmohan Revathy; Winterbourn Christine C; Kettle Anthony J
Chlorination of bacterial and neutrophil proteins during phagocytosis and killing of Staphylococcus aureus.
The Journal of biological chemistry 2002;277(12):9757-62.
2002: Pullar Juliet M; Winterbourn Christine C; Vissers Margret C M
The effect of hypochlorous acid on the expression of adhesion molecules and activation of NF-kappaB in cultured human endothelial cells.
Antioxidants & redox signaling 2002;4(1):5-15.
2002: Hampton Mark B; Winterbourn Christine C
Redox regulation of neutrophil function.
Antioxidants & redox signaling 2002;4(1):1-3.
2002: Winterbourn Christine C; Peskin Alexander V; Parsons-Mair Helena N
Thiol oxidase activity of copper, zinc superoxide dismutase.
The Journal of biological chemistry 2002;277(3):1906-11.
2002: Buss I Hendrikje; Winterbourn Christine C
Protein carbonyl measurement by ELISA.
Methods in molecular biology (Clifton, N.J.) 2002;186():123-8.
2001: Midwinter R G; Vissers M C; Winterbourn C C
Hypochlorous acid stimulation of the mitogen-activated protein kinase pathway enhances cell survival.
Archives of biochemistry and biophysics 2001;394(1):13-20.
2001: Kettle A J; Winterbourn C C
A kinetic analysis of the catalase activity of myeloperoxidase.
Biochemistry 2001;40(34):10204-12.
2001: Buss I H; McGill F; Darlow B A; Winterbourn C C
Vitamin C is reduced in human milk after storage.
Acta paediatrica (Oslo, Norway : 1992) 2001;90(7):813-5.
2001: Pullar J M; Vissers M C; Winterbourn C C
Glutathione oxidation by hypochlorous acid in endothelial cells produces glutathione sulfonamide as a major product but not glutathione disulfide.
The Journal of biological chemistry 2001;276(25):22120-5.
2001: Silvers K M; Sluis K B; Darlow B A; McGill F; Stocker R; Winterbourn C C
Limiting light-induced lipid peroxidation and vitamin loss in infant parenteral nutrition by adding multivitamin preparations to Intralipid.
Acta paediatrica (Oslo, Norway : 1992) 2001;90(3):242-9.
2001: Peskin A V; Winterbourn C C
Kinetics of the reactions of hypochlorous acid and amino acid chloramines with thiols, methionine, and ascorbate.
Free radical biology & medicine 2001;30(5):572-9.
2001: Silvers K M; Darlow B A; Winterbourn C C
Lipid peroxide and hydrogen peroxide formation in parenteral nutrition solutions containing multivitamins.
JPEN. Journal of parenteral and enteral nutrition 2001;25(1):14-7.
2000: Pullar J M; Vissers M C; Winterbourn C C
Living with a killer: the effects of hypochlorous acid on mammalian cells.
IUBMB life 2000;50(4-5):259-66.
2000: Winterbourn C C; Kettle A J
Biomarkers of myeloperoxidase-derived hypochlorous acid.
Free radical biology & medicine 2000;29(5):403-9.
2000: Winterbourn C C; Chan T; Buss I H; Inder T E; Mogridge N; Darlow B A
Protein carbonyls and lipid peroxidation products as oxidation markers in preterm infant plasma: associations with chronic lung disease and retinopathy and effects of selenium supplementation.
Pediatric research 2000;48(1):84-90.
2000: Buss I H; Darlow B A; Winterbourn C C
Elevated protein carbonyls and lipid peroxidation products correlating with myeloperoxidase in tracheal aspirates from premature infants.
Pediatric research 2000;47(5):640-5.
2000: Chapman A L; Senthilmohan R; Winterbourn C C; Kettle A J
Comparison of mono- and dichlorinated tyrosines with carbonyls for detection of hypochlorous acid modified proteins.
Archives of biochemistry and biophysics 2000;377(1):95-100.
2000: van Dalen C J; Winterbourn C C; Senthilmohan R; Kettle A J
Nitrite as a substrate and inhibitor of myeloperoxidase. Implications for nitration and hypochlorous acid production at sites of inflammation.
The Journal of biological chemistry 2000;275(16):11638-44.
2000: Darlow B A; Winterbourn C C; Inder T E; Graham P J; Harding J E; Weston P J; Austin N C; Elder D E; Mogridge N; Buss I H; Sluis K B
The effect of selenium supplementation on outcome in very low birth weight infants: a randomized controlled trial. The New Zealand Neonatal Study Group.
The Journal of pediatrics 2000;136(4):473-80.
2000: Peskin A V; Winterbourn C C
A microtiter plate assay for superoxide dismutase using a water-soluble tetrazolium salt (WST-1).
Clinica chimica acta; international journal of clinical chemistry 2000;293(1-2):157-66.
2000: Winterbourn C C; Buss I H; Chan T P; Plank L D; Clark M A; Windsor J A
Protein carbonyl measurements show evidence of early oxidative stress in critically ill patients.
Critical care medicine 2000;28(1):143-9.
1999: Hampton M B; Winterbourn C C
Methods for quantifying phagocytosis and bacterial killing by human neutrophils.
Journal of immunological methods 1999;232(1-2):15-22.
1999: Pullar J M; Winterbourn C C; Vissers M C
Loss of GSH and thiol enzymes in endothelial cells exposed to sublethal concentrations of hypochlorous acid.
The American journal of physiology 1999;277(4 Pt 2):H1505-12.
1999: Winterbourn C C; Metodiewa D
Reactivity of biologically important thiol compounds with superoxide and hydrogen peroxide.
Free radical biology & medicine 1999;27(3-4):322-8.
1999: Winterbourn C C; Buss I H
Protein carbonyl measurement by enzyme-linked immunosorbent assay.
Methods in enzymology 1999;300():106-11.
1998: Hampton M B; Kettle A J; Winterbourn C C
Inside the neutrophil phagosome: oxidants, myeloperoxidase, and bacterial killing.
Blood 1998;92(9):3007-17.
1998: Inder T E; Graham P J; Winterbourn C C; Austin N C; Darlow B A
Plasma vitamin A levels in the very low birthweight infant--relationship to respiratory outcome.
Early human development 1998;52(2):155-68.
1998: Silvers K M; Darlow B A; Winterbourn C C
Pharmacologic levels of heparin do not destabilize neonatal parenteral nutrition.
JPEN. Journal of parenteral and enteral nutrition 1998;22(5):311-4.
1998: Vollebregt M; Hampton M B; Winterbourn C C
Activation of NF-kappaB in human neutrophils during phagocytosis of bacteria independently of oxidant generation.
FEBS letters 1998;432(1-2):40-4.
1998: Carr A C; van den Berg J J; Winterbourn C C
Differential reactivities of hypochlorous and hypobromous acids with purified Escherichia coli phospholipid: formation of haloamines and halohydrins.
Biochimica et biophysica acta 1998;1392(2-3):254-64.
1997: Carr A C; Vissers M C; Domigan N M; Winterbourn C C
Modification of red cell membrane lipids by hypochlorous acid and haemolysis by preformed lipid chlorohydrins.
Redox report : communications in free radical research 1997;3(5-6):263-71.
1997: Kettle A J; van Dalen C J; Winterbourn C C
Peroxynitrite and myeloperoxidase leave the same footprint in protein nitration.
Redox report : communications in free radical research 1997;3(5-6):257-8.
1997: Silvers K M; Winterbourn C C
The destabilisation of total parenteral nutrition by heparin. How real is the problem?
The New Zealand medical journal 1997;110(1053):386.
1997: van Dalen C J; Whitehouse M W; Winterbourn C C; Kettle A J
Thiocyanate and chloride as competing substrates for myeloperoxidase.
The Biochemical journal 1997;327 ( Pt 2)():487-92.
1997: Carr A C; Winterbourn C C
Oxidation of neutrophil glutathione and protein thiols by myeloperoxidase-derived hypochlorous acid.
The Biochemical journal 1997;327 ( Pt 1)():275-81.
1997: Winterbourn C C; Brennan S O
Characterization of the oxidation products of the reaction between reduced glutathione and hypochlorous acid.
The Biochemical journal 1997;326 ( Pt 1)():87-92.
1997: Carr A C; Winterbourn C C; Blunt J W; Phillips A J; Abell A D
Nuclear magnetic resonance characterization of 6 alpha-chloro-5 beta-cholestane-3 beta,5-diol formed from the reaction of hypochlorous acid with cholesterol.
Lipids 1997;32(4):363-7.
1997: Darlow B A; Sluis K B; Inder T E; Winterbourn C C
Endotracheal suctioning of the neonate: comparison of two methods as a source of mucus material for research.
Pediatric pulmonology 1997;23(3):217-21.
1997: Winterbourn C C; Pichorner H; Kettle A J
Myeloperoxidase-dependent generation of a tyrosine peroxide by neutrophils.
Archives of biochemistry and biophysics 1997;338(1):15-21.
1997: Kettle A J; Gedye C A; Winterbourn C C
Mechanism of inactivation of myeloperoxidase by 4-aminobenzoic acid hydrazide.
The Biochemical journal 1997;321 ( Pt 2)():503-8.
1997: Buss H; Chan T P; Sluis K B; Domigan N M; Winterbourn C C
Protein carbonyl measurement by a sensitive ELISA method.
Free radical biology & medicine 1997;23(3):361-6.
1996: Inder T E; Darlow B A; Sluis K B; Winterbourn C C; Graham P; Sanderson K J; Taylor B J
The correlation of elevated levels of an index of lipid peroxidation (MDA-TBA) with adverse outcome in the very low birthweight infant.
Acta paediatrica (Oslo, Norway : 1992) 1996;85(9):1116-22.
1996: Hampton M B; Kettle A J; Winterbourn C C
Involvement of superoxide and myeloperoxidase in oxygen-dependent killing of Staphylococcus aureus by neutrophils.
Infection and immunity 1996;64(9):3512-7.
1996: Carr A C; van den Berg J J; Winterbourn C C
Chlorination of cholesterol in cell membranes by hypochlorous acid.
Archives of biochemistry and biophysics 1996;332(1):63-9.
1996: Carr A C; Winterbourn C C; van den Berg J J
Peroxidase-mediated bromination of unsaturated fatty acids to form bromohydrins.
Archives of biochemistry and biophysics 1996;327(2):227-33.
1995: Winterbourn C C
Toxicity of iron and hydrogen peroxide: the Fenton reaction.
Toxicology letters 1995;82-83():969-74.
1995: Pichorner H; Metodiewa D; Winterbourn C C
Generation of superoxide and tyrosine peroxide as a result of tyrosyl radical scavenging by glutathione.
Archives of biochemistry and biophysics 1995;323(2):429-37.
1995: Darlow B A; Inder T E; Graham P J; Sluis K B; Malpas T J; Taylor B J; Winterbourn C C
The relationship of selenium status to respiratory outcome in the very low birth weight infant.
Pediatrics 1995;96(2 Pt 1):314-9.
1995: Darlow B A; Inder T E; Sluis K B; Nuthall G; Mogridge N; Winterbourn C C
Selenium status of New Zealand infants fed either a selenium supplemented or a standard formula.
Journal of paediatrics and child health 1995;31(4):339-44.
1995: Winterbourn C C; Domigan N M; Broom J K
Decreased thermal stability of red blood cell glu100-->gly superoxide dismutase from a family with amyotrophic lateral sclerosis.
FEBS letters 1995;368(3):449-51.
1995: Kettle A J; Gedye C A; Hampton M B; Winterbourn C C
Inhibition of myeloperoxidase by benzoic acid hydrazides.
The Biochemical journal 1995;308 ( Pt 2)():559-63.
1995: Neuzil J; Darlow B A; Inder T E; Sluis K B; Winterbourn C C; Stocker R
Oxidation of parenteral lipid emulsion by ambient and phototherapy lights: potential toxicity of routine parenteral feeding.
The Journal of pediatrics 1995;126(5 Pt 1):785-90.
1995: Hampton M B; Winterbourn C C
Modification of neutrophil oxidant production with diphenyleneiodonium and its effect on bacterial killing.
Free radical biology & medicine 1995;18(4):633-9.
1995: Vissers M C; Winterbourn C C
Oxidation of intracellular glutathione after exposure of human red blood cells to hypochlorous acid.
The Biochemical journal 1995;307 ( Pt 1)():57-62.
1995: Calder V L; Domigan N M; George P M; Donaldson I M; Winterbourn C C
Superoxide dismutase (glu100-->gly) in a family with inherited motor neuron disease: detection of mutant superoxide dismutase activity and the presence of heterodimers.
Neuroscience letters 1995;189(3):143-6.
1995: Inder T E; Carr A C; Winterbourn C C; Austin N C; Darlow B A
Vitamin A and E status in very low birth weight infants: development of an improved parenteral delivery system.
The Journal of pediatrics 1995;126(1):128-31.
1995: Winterbourn C C; Metodiewa D
Reaction of superoxide with glutathione and other thiols.
Methods in enzymology 1995;251():81-6.
1994: Winterbourn C C; Metodiewa D
The reaction of superoxide with reduced glutathione.
Archives of biochemistry and biophysics 1994;314(2):284-90.
1994: Thomas C; Carr A C; Winterbourn C C
Free radical inactivation of rabbit muscle creatinine kinase: catalysis by physiological and hydrolyzed ICRF-187 (ICRF-198) iron chelates.
Free radical research 1994;21(6):387-97.
1994: Kettle A J; Carr A C; Winterbourn C C
Assays using horseradish peroxidase and phenolic substrates require superoxide dismutase for accurate determination of hydrogen peroxide production by neutrophils.
Free radical biology & medicine 1994;17(2):161-4.
1994: Kettle A J; Winterbourn C C
Superoxide-dependent hydroxylation by myeloperoxidase.
The Journal of biological chemistry 1994;269(25):17146-51.
1994: Hampton M B; Chambers S T; Vissers M C; Winterbourn C C
Bacterial killing by neutrophils in hypertonic environments.
The Journal of infectious diseases 1994;169(4):839-46.
1994: Hampton M B; Vissers M C; Winterbourn C C
A single assay for measuring the rates of phagocytosis and bacterial killing by neutrophils.
Journal of leukocyte biology 1994;55(2):147-52.
1994: Sluis K B; Darlow B A; Vissers M C; Winterbourn C C
Proteinase-antiproteinase balance in tracheal aspirates from neonates.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1994;7(2):251-9.
1993: Kettle A J; Gedye C A; Winterbourn C C
Superoxide is an antagonist of antiinflammatory drugs that inhibit hypochlorous acid production by myeloperoxidase.
Biochemical pharmacology 1993;45(10):2003-10.
1993: Thomas C; Vile G F; Winterbourn C C
The hydrolysis product of ICRF-187 promotes iron-catalysed hydroxyl radical production via the Fenton reaction.
Biochemical pharmacology 1993;45(10):1967-72.
1993: Winterbourn C C; Carr A C
Myeloperoxidase-dependent loss of malondialdehyde: a limitation for detecting neutrophil-mediated lipid peroxidation.
Archives of biochemistry and biophysics 1993;302(2):461-7.
1993: Winterbourn C C
Superoxide as an intracellular radical sink.
Free radical biology & medicine 1993;14(1):85-90.
1992: Winterbourn C C; Saville D J; George P M; Walmsley T A
Increase in selenium status of Christchurch adults associated with deregulation of the wheat market.
The New Zealand medical journal 1992;105(946):466-8.
1992: Sluis K B; Darlow B A; George P M; Mogridge N; Dolamore B A; Winterbourn C C
Selenium and glutathione peroxidase levels in premature infants in a low selenium community (Christchurch, New Zealand).
Pediatric research 1992;32(2):189-94.
1992: Dolamore B A; Brown J; Darlow B A; George P M; Sluis K B; Winterbourn C C
Selenium status of Christchurch infants and the effect of diet.
The New Zealand medical journal 1992;105(932):139-42.
1992: Kettle A J; Winterbourn C C
Oxidation of hydroquinone by myeloperoxidase. Mechanism of stimulation by benzoquinone.
The Journal of biological chemistry 1992;267(12):8319-24.
1992: Michaelis J; Vissers M C; Winterbourn C C
Different effects of hypochlorous acid on human neutrophil metalloproteinases: activation of collagenase and inactivation of collagenase and gelatinase.
Archives of biochemistry and biophysics 1992;292(2):555-62.
1992: Michaelis J; Vissers M C; Winterbourn C C
Cleavage of alpha 1-antitrypsin by human neutrophil collagenase.
Matrix (Stuttgart, Germany). Supplement 1992;1():80-1.
1991: Kettle A J; Winterbourn C C
Mechanism of inhibition of myeloperoxidase by anti-inflammatory drugs.
Biochemical pharmacology 1991;41(10):1485-92.
1991: Vissers M C; Winterbourn C C
Oxidative damage to fibronectin. II. The effect of H2O2 and the hydroxyl radical.
Archives of biochemistry and biophysics 1991;285(2):357-64.
1991: Vissers M C; Winterbourn C C
Oxidative damage to fibronectin. I. The effects of the neutrophil myeloperoxidase system and HOCl.
Archives of biochemistry and biophysics 1991;285(1):53-9.
1991: Winterbourn C C
Factors that influence the deoxyribose oxidation assay for Fenton reaction products.
Free radical biology & medicine 1991;11(4):353-60.
1991: Kettle A J; Winterbourn C C
The influence of superoxide on the production of hypochlorous acid by human neutrophils.
Free radical research communications 1991;12-13 Pt 1():47-52.
1991: Monteiro H P; Winterbourn C C; Stern A
Tetravalent vanadium releases ferritin iron which stimulates vanadium-dependent lipid peroxidation.
Free radical research communications 1991;12-13 Pt 1():125-9.
1991: Winterbourn C C; Vile G F; Monteiro H P
Ferritin, lipid peroxidation and redox-cycling xenobiotics.
Free radical research communications 1991;12-13 Pt 1():107-14.
1990: Winterbourn C C; Monteiro H P; Galilee C F
Ferritin-dependent lipid peroxidation by stimulated neutrophils: inhibition by myeloperoxidase-derived hypochlorous acid but not by endogenous lactoferrin.
Biochimica et biophysica acta 1990;1055(2):179-85.
1990: Michaelis J; Vissers M C; Winterbourn C C
Human neutrophil collagenase cleaves alpha 1-antitrypsin.
The Biochemical journal 1990;270(3):809-14.
1990: Kettle A J; Winterbourn C C
Superoxide enhances hypochlorous acid production by stimulated human neutrophils.
Biochimica et biophysica acta 1990;1052(3):379-85.
1990: Vile G F; Winterbourn C C
dl-N,N'-dicarboxamidomethyl-N,N'-dicarboxymethyl-1,2-diaminopropane (ICRF-198) and d-1,2-bis(3,5-dioxopiperazine-1-yl)propane (ICRF-187) inhibition of Fe3+ reduction, lipid peroxidation, and CaATPase inactivation in heart microsomes exposed to adriamycin.
Cancer research 1990;50(8):2307-10.
1990: Vile G; Winterbourn C
Thiol oxidation and inhibition of Ca-ATPase by adriamycin in rabbit heart microsomes.
Biochemical pharmacology 1990;39(4):769-74.
1990: Molloy A L; Winterbourn C C
Release of iron from phagocytosed Escherichia coli and uptake by neutrophil lactoferrin.
Blood 1990;75(4):984-9.
1990: Winterbourn C C; Munday R
Concerted action of reduced glutathione and superoxide dismutase in preventing redox cycling of dihydroxypyrimidines, and their role in antioxidant defence.
Free radical research communications 1990;8(4-6):287-93.
1989: Monteiro H P; Winterbourn C C
6-Hydroxydopamine releases iron from ferritin and promotes ferritin-dependent lipid peroxidation.
Biochemical pharmacology 1989;38(23):4177-82.
1989: Kettle A J; Winterbourn C C
Influence of superoxide on myeloperoxidase kinetics measured with a hydrogen peroxide electrode.
The Biochemical journal 1989;263(3):823-8.
1989: Monteiro H P; Winterbourn C C
Release of iron from ferritin by divicine, isouramil, acid-hydrolyzed vicine, and dialuric acid and initiation of lipid peroxidation.
Archives of biochemistry and biophysics 1989;271(2):536-45.
1989: Winterbourn C C; Munday R
Glutathione-mediated redox cycling of alloxan. Mechanisms of superoxide dismutase inhibition and of metal-catalyzed OH. formation.
Biochemical pharmacology 1989;38(2):271-7.
1989: Monteiro H P; Vile G F; Winterbourn C C
An iron chelator is not required for reductive iron release from ferritin by radical generating systems.
Free radical research communications 1989;7(1):33-5.
1989: Monteiro H P; Vile G F; Winterbourn C C
Release of iron from ferritin by semiquinone, anthracycline, bipyridyl, and nitroaromatic radicals.
Free radical biology & medicine 1989;6(6):587-91.
1989: Vile G F; Winterbourn C C
Microsomal lipid peroxidation induced by adriamycin, epirubicin, daunorubicin and mitoxantrone: a comparative study.
Cancer chemotherapy and pharmacology 1989;24(2):105-8.
1988: Monteiro H P; Winterbourn C C
The superoxide-dependent transfer of iron from ferritin to transferrin and lactoferrin.
The Biochemical journal 1988;256(3):923-8.
1988: Vile G F; Winterbourn C C
Microsomal reduction of low-molecular-weight Fe3+ chelates and ferritin: enhancement by adriamycin, paraquat, menadione, and anthraquinone 2-sulfonate and inhibition by oxygen.
Archives of biochemistry and biophysics 1988;267(2):606-13.
1988: Kettle A J; Winterbourn C C
The mechanism of myeloperoxidase-dependent chlorination of monochlorodimedon.
Biochimica et biophysica acta 1988;957(2):185-91.
1988: Vile G F; Winterbourn C C
Inhibition of adriamycin-promoted microsomal lipid peroxidation by beta-carotene, alpha-tocopherol and retinol at high and low oxygen partial pressures.
FEBS letters 1988;238(2):353-6.
1988: Vile G F; Winterbourn C C
Adriamycin-dependent peroxidation of rat liver and heart microsomes catalysed by iron chelates and ferritin. Maximum peroxidation at low oxygen partial pressures.
Biochemical pharmacology 1988;37(15):2893-7.
1988: Kettle A J; Sangster D F; Gebicki J M; Winterbourn C C
A pulse radiolysis investigation of the reactions of myeloperoxidase with superoxide and hydrogen peroxide.
Biochimica et biophysica acta 1988;956(1):58-62.
1988: Vissers M C; George P M; Bathurst I C; Brennan S O; Winterbourn C C
Cleavage and inactivation of alpha 1-antitrypsin by metalloproteinases released from neutrophils.
The Journal of clinical investigation 1988;82(2):706-11.
1988: Kettle A J; Winterbourn C C
Superoxide modulates the activity of myeloperoxidase and optimizes the production of hypochlorous acid.
The Biochemical journal 1988;252(2):529-36.
1988: Winterbourn C C; Molloy A L
Susceptibilities of lactoferrin and transferrin to myeloperoxidase-dependent loss of iron-binding capacity.
The Biochemical journal 1988;250(2):613-6.
1987: Vile G F; Winterbourn C C; Sutton H C
Radical-driven Fenton reactions: studies with paraquat, adriamycin, and anthraquinone 6-sulfonate and citrate, ATP, ADP, and pyrophosphate iron chelates.
Archives of biochemistry and biophysics 1987;259(2):616-26.
1987: Winterbourn C C; Stern A
Human red cells scavenge extracellular hydrogen peroxide and inhibit formation of hypochlorous acid and hydroxyl radical.
The Journal of clinical investigation 1987;80(5):1486-91.
1987: Sutton H C; Vile G F; Winterbourn C C
Radical driven Fenton reactions--evidence from paraquat radical studies for production of tetravalent iron in the presence and absence of ethylenediaminetetraacetic acid.
Archives of biochemistry and biophysics 1987;256(2):462-71.

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