FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Christine Winterbourn

Research Profile

Chemicals & Drugs

Co-author Network

Publications

TOP 3
Vikas Kumar; Mark B Cannell; Mark B Hampton; Torsten Kleffmann; Christine C Winterbourn
Redox proteomics of thiol proteins in mouse heart during ischemia/reperfusion using ICAT reagents and mass spectrometry.
Anna L P Chapman; Brian Chen; Guy N L Jameson; Irada Khalilova; Tessa J Mocatta; Martina E Paumann-Page; Antonia Seidel; Sruti Shiva; Christine C Winterbourn; Anthony J Kettle
Ceruloplasmin is an endogenous inhibitor of myeloperoxidase.
Christine C Winterbourn; Anthony J Kettle
Redox reactions and microbial killing in the neutrophil phagosome.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Christine Winterbourn (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Vikas Kumar; Mark B Cannell; Mark B Hampton; Torsten Kleffmann; Christine C Winterbourn
Redox proteomics of thiol proteins in mouse heart during ischemia/reperfusion using ICAT reagents and mass spectrometry.
Free radical biology & medicine 2013;58():109-17.
2013: Anna L P Chapman; Brian Chen; Guy N L Jameson; Irada Khalilova; Tessa J Mocatta; Martina E Paumann-Page; Antonia Seidel; Sruti Shiva; Christine C Winterbourn; Anthony J Kettle
Ceruloplasmin is an endogenous inhibitor of myeloperoxidase.
The Journal of biological chemistry 2013;288(9):6465-77.
2013: Christine C Winterbourn; Anthony J Kettle
Redox reactions and microbial killing in the neutrophil phagosome.
Antioxidants & redox signaling 2013;18(6):642-60.
2013: Seymour J Klebanoff; Henry Rosen; Christine C Winterbourn; Anthony J Kettle; William M Nauseef
Myeloperoxidase: a front-line defender against phagocytosed microorganisms.
Journal of leukocyte biology 2013;93(2):185-98.
2012: Melissa Stacey; Sarah L Cuddihy; Mark B Hampton; Christine C Winterbourn
Protein thiol oxidation and formation of S-glutathionylated cyclophilin A in cells exposed to chloramines and hypochlorous acid.
Archives of biochemistry and biophysics 2012;527(1):45-54.
2012: Geoffrey F Kelso; Angela Logan; Andrej Maroz; Michael P Murphy; Alexander V Peskin; Carolyn M Porteous; Tracy A Prime; Meredith F Ross; Robert F Anderson; Sally Brooker; Helena M Cochemé; Andrew M James; Christine C Winterbourn; Robin A J Smith
A mitochondria-targeted macrocyclic Mn(II) superoxide dismutase mimetic.
Chemistry & biology 2012;19(10):1237-46.
2012: Heather Parker; Mike Dragunow; Mark B Hampton; Anthony J Kettle; Christine C Winterbourn
Requirements for NADPH oxidase and myeloperoxidase in neutrophil extracellular trap formation differ depending on the stimulus.
Journal of leukocyte biology 2012;92(4):841-9.
2012: Melissa M Stacey; Margreet C Vissers; Christine C Winterbourn
Oxidation of 2-cys peroxiredoxins in human endothelial cells by hydrogen peroxide, hypochlorous acid, and chloramines.
Antioxidants & redox signaling 2012;17(3):411-21.
2012: Peter Nagy; Andrew B Das; Thomas P Lechte; Christine C Winterbourn
Conjugation of glutathione to oxidized tyrosine residues in peptides and proteins.
The Journal of biological chemistry 2012;287(31):26068-76.
2012: Heather Parker; Amelia M Albrett; Anthony J Kettle; Christine C Winterbourn
Myeloperoxidase associated with neutrophil extracellular traps is active and mediates bacterial killing in the presence of hydrogen peroxide.
Journal of leukocyte biology 2012;91(3):369-76.
2012: Heather Parker; Christine C Winterbourn
Reactive oxidants and myeloperoxidase and their involvement in neutrophil extracellular traps.
Frontiers in immunology 2012;3():424.
2011: Anthony J Kettle; Andrej Maroz; Christine C Winterbourn; Grant Woodroffe; Robert F Anderson
Spectral and kinetic evidence for reaction of superoxide with compound I of myeloperoxidase.
Free radical biology & medicine 2011;51(12):2190-4.
2011: Amber Parker; Tae G Son; Margreet C M Vissers; Sarah L Cuddihy; Christine C Winterbourn
Roles of superoxide and myeloperoxidase in ascorbate oxidation in stimulated neutrophils and H2O2-treated HL60 cells.
Free radical biology & medicine 2011;51(7):1399-405.
2011: Sarah L Cuddihy; Christine C Winterbourn; Mark Hampton
Assessment of redox changes to hydrogen peroxide-sensitive proteins during EGF signaling.
Antioxidants & redox signaling 2011;15(1):167-74.
2011: Péter Nagy; Amir Karton; Andrea Betz; Alexander V Peskin; Paul Pace; Robert J O'Reilly; Mark Hampton; Leo Radom; Christine C Winterbourn
Model for the exceptional reactivity of peroxiredoxins 2 and 3 with hydrogen peroxide: a kinetic and computational study.
The Journal of biological chemistry 2011;286(20):18048-55.
2011: Michael P Murphy; Arne Holmgren; Nils-Göran Larsson; Barry Halliwell; Christopher J Chang; Balaraman Kalyanaraman; Sue Goo Rhee; Paul J Thornalley; Linda Partridge; David Gems; Thomas Nyström; Vsevolod Belousov; Paul T Schumacker; Christine C Winterbourn
Unraveling the biological roles of reactive oxygen species.
Cell metabolism 2011;13(4):361-6.
2011: D Tim Harwood; Brian A Darlow; Fook-Choe Cheah; Nicolette McNeill; Patricia Graham; Christine C Winterbourn
Biomarkers of neutrophil-mediated glutathione and protein oxidation in tracheal aspirates from preterm infants: association with bacterial infection.
Pediatric research 2011;69(1):28-33.
2010: Alexander V Peskin; Andrew G Cox; Péter Nagy; Philip E Morgan; Mark Hampton; Michael J Davies; Christine C Winterbourn
Removal of amino acid, peptide and protein hydroperoxides by reaction with peroxiredoxins 2 and 3.
The Biochemical journal 2010;432(2):313-21.
2010: Péter Nagy; Christine C Winterbourn
Rapid reaction of hydrogen sulfide with the neutrophil oxidant hypochlorous acid to generate polysulfides.
Chemical research in toxicology 2010;23(10):1541-3.
2010: Péter Nagy; Anthony J Kettle; Christine C Winterbourn
Neutrophil-mediated oxidation of enkephalins via myeloperoxidase-dependent addition of superoxide.
Free radical biology & medicine 2010;49(5):792-9.
2010: Catriona J Marshall; Mark Nallaratnam; Tessa Mocatta; David Smyth; Mark Richards; John M Elliott; James Blake; Christine C Winterbourn; Anthony J Kettle; Dougal R McClean
Factors influencing local and systemic levels of plasma myeloperoxidase in ST-segment elevation acute myocardial infarction.
The American journal of cardiology 2010;106(3):316-22.
2010: Andrew B Das; Péter Nagy; Helen F Abbott; Christine C Winterbourn; Anthony J Kettle
Reactions of superoxide with the myoglobin tyrosyl radical.
Free radical biology & medicine 2010;48(11):1540-7.
2010: Andrew G Cox; Christine C Winterbourn; Mark Hampton
Mitochondrial peroxiredoxin involvement in antioxidant defence and redox signalling.
The Biochemical journal 2010;425(2):313-25.
2010: Louise N Paton; Tessa J Mocatta; A Mark Richards; Christine C Winterbourn
Increased thrombin-induced polymerization of fibrinogen associated with high protein carbonyl levels in plasma from patients post myocardial infarction.
Free radical biology & medicine 2010;48(2):223-9.
2010: Andrew G Cox; Christine C Winterbourn; Mark B Hampton
Measuring the redox state of cellular peroxiredoxins by immunoblotting.
Methods in enzymology 2010;474():51-66.
2010: valdecir ximenes; Ghassan J Maghzal; Rufus Turner; Yoji Kato; Christine C Winterbourn; Anthony J Kettle
Serotonin as a physiological substrate for myeloperoxidase and its superoxide-dependent oxidation to cytotoxic tryptamine-4,5-dione.
The Biochemical journal 2010;425(1):285-93.
2009: Kristin K Brown; Frances H Blaikie; Robin A J Smith; Joel D A Tyndall; Hongqi Lue; Jürgen Bernhagen; Christine C Winterbourn; Mark Hampton
Direct modification of the proinflammatory cytokine macrophage migration inhibitory factor by dietary isothiocyanates.
The Journal of biological chemistry 2009;284(47):32425-33.
2009: Melissa Stacey; Alexander V Peskin; Margret C M Vissers; Christine C Winterbourn
Chloramines and hypochlorous acid oxidize erythrocyte peroxiredoxin 2.
Free radical biology & medicine 2009;47(10):1468-76.
2009: Péter Nagy; Guy N L Jameson; Christine C Winterbourn
Kinetics and mechanisms of the reaction of hypothiocyanous acid with 5-thio-2-nitrobenzoic acid and reduced glutathione.
Chemical research in toxicology 2009;22(11):1833-40.
2009: Alexander V Peskin; Rufus Turner; Ghassan J Maghzal; Christine C Winterbourn; Anthony J Kettle
Oxidation of methionine to dehydromethionine by reactive halogen species generated by neutrophils.
Biochemistry 2009;48(42):10175-82.
2009: D Tim Harwood; Anthony J Kettle; Siobhain Brennan; Christine C Winterbourn
Simultaneous determination of reduced glutathione, glutathione disulphide and glutathione sulphonamide in cells and physiological fluids by isotope dilution liquid chromatography-tandem mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2009;877(28):3393-9.
2009: Andrew G Cox; Alexander V Peskin; Louise N Paton; Christine C Winterbourn; Mark B Hampton
Redox potential and peroxide reactivity of human peroxiredoxin 3.
Biochemistry 2009;48(27):6495-501.
2009: Andrew G Cox; Andree G Pearson; Juliet M Pullar; Thomas J Jönsson; W Todd Lowther; Christine C Winterbourn; Mark B Hampton
Mitochondrial peroxiredoxin 3 is more resilient to hyperoxidation than cytoplasmic peroxiredoxins.
The Biochemical journal 2009;421(1):51-8.
2009: Péter Nagy; Anthony J Kettle; Christine C Winterbourn
Superoxide-mediated formation of tyrosine hydroperoxides and methionine sulfoxide in peptides through radical addition and intramolecular oxygen transfer.
The Journal of biological chemistry 2009;284(22):14723-33.
2009: Vikas Kumar; Nailya Kitaeff; Mark B Hampton; Mark Cannell; Christine C Winterbourn
Reversible oxidation of mitochondrial peroxiredoxin 3 in mouse heart subjected to ischemia and reperfusion.
FEBS letters 2009;583(6):997-1000.
2009: Barry Palmer; Courtney L Devereaux; Sukhbir S Dhamrait; Tessa J Mocatta; Anna P Pilbrow; Christopher M Frampton; Lorraine Skelton; Timothy G Yandle; Christine C Winterbourn; A Mark Richards; Hugh E Montgomery; Vicky A Cameron
The common G-866A polymorphism of the UCP2 gene and survival in diabetic patients following myocardial infarction.
Cardiovascular diabetology 2009;8():31.
2009: Sarah L Cuddihy; James W Baty; Kristin K Brown; Christine C Winterbourn; Mark B Hampton
Proteomic detection of oxidized and reduced thiol proteins in cultured cells.
Methods in molecular biology (Clifton, N.J.) 2009;519():363-75.
2008: Christine C Winterbourn; Mark B Hampton
Thiol chemistry and specificity in redox signaling.
Free radical biology & medicine 2008;45(5):549-61.
2008: Felicia M Low; Mark Hampton; Christine C Winterbourn
Peroxiredoxin 2 and peroxide metabolism in the erythrocyte.
Antioxidants & redox signaling 2008;10(9):1621-30.
2008: Mhoyra Fraser; Laura Bennet; Pierre L van Zijl; Tessa J Mocatta; Christopher E Williams; Peter D Gluckman; Christine C Winterbourn; Alistair J Gunn
Extracellular amino acids and lipid peroxidation products in periventricular white matter during and after cerebral ischemia in preterm fetal sheep.
Journal of neurochemistry 2008;105(6):2214-23.
2008: David T Harwood; Susan L Nimmo; Anthony J Kettle; Christine C Winterbourn; Michael T Ashby
Molecular structure and dynamic properties of a sulfonamide derivative of glutathione that is produced under conditions of oxidative stress by hypochlorous acid.
Chemical research in toxicology 2008;21(5):1011-6.
2008: Christine C Winterbourn
Reconciling the chemistry and biology of reactive oxygen species.
Nature chemical biology 2008;4(5):278-86.
2008: Sarah L Cuddihy; Amber Parker; D Tim Harwood; Margreet C M Vissers; Christine C Winterbourn
Ascorbate interacts with reduced glutathione to scavenge phenoxyl radicals in HL60 cells.
Free radical biology & medicine 2008;44(8):1637-44.
2007: Bo Akerström; Ghassan J Maghzal; Christine C Winterbourn; Anthony J Kettle
The lipocalin alpha1-microglobulin has radical scavenging activity.
The Journal of biological chemistry 2007;282(43):31493-503.
2007: Tessa J Mocatta; Anna P Pilbrow; Vicky A Cameron; Revathy Senthilmohan; Christopher M Frampton; A Mark Richards; Christine C Winterbourn
Plasma concentrations of myeloperoxidase predict mortality after myocardial infarction.
Journal of the American College of Cardiology 2007;49(20):1993-2000.
2007: Anthony J Kettle; Robert F Anderson; Mark Hampton; Christine C Winterbourn
Reactions of superoxide with myeloperoxidase.
Biochemistry 2007;46(16):4888-97.
2007: Alexander V Peskin; Felicia M Low; Louise N Paton; Ghassan J Maghzal; Mark Hampton; Christine C Winterbourn
The high reactivity of peroxiredoxin 2 with H(2)O(2) is not reflected in its reaction with other oxidants and thiol reagents.
The Journal of biological chemistry 2007;282(16):11885-92.
2007: Felicia M Low; Mark Hampton; Alexander V Peskin; Christine C Winterbourn
Peroxiredoxin 2 functions as a noncatalytic scavenger of low-level hydrogen peroxide in the erythrocyte.
Blood 2007;109(6):2611-7.
2007: Jessie N Green; Christine C Winterbourn; Mark Hampton
Analysis of neutrophil bactericidal activity.
Methods in molecular biology (Clifton, N.J.) 2007;412():319-32.
2006: Christine C Winterbourn; Mark Hampton; John H Livesey; Anthony J Kettle
Modeling the reactions of superoxide and myeloperoxidase in the neutrophil phagosome: implications for microbial killing.
The Journal of biological chemistry 2006;281(52):39860-9.
2006: David T Harwood; Anthony J Kettle; Christine C Winterbourn
Production of glutathione sulfonamide and dehydroglutathione from GSH by myeloperoxidase-derived oxidants and detection using a novel LC-MS/MS method.
The Biochemical journal 2006;399(1):161-8.
2006: Vicky A Cameron; Tessa J Mocatta; Anna P Pilbrow; Christopher M Frampton; Richard W Troughton; A Mark Richards; Christine C Winterbourn
Angiotensin type-1 receptor A1166C gene polymorphism correlates with oxidative stress levels in human heart failure.
Hypertension 2006;47(6):1155-61.
2006: Robyn G Midwinter; Fook-Choe Cheah; Jackob Moskovitz; Margret C M Vissers; Christine C Winterbourn
IkappaB is a sensitive target for oxidation by cell-permeable chloramines: inhibition of NF-kappaB activity by glycine chloramine through methionine oxidation.
The Biochemical journal 2006;396(1):71-8.
2006: Christine J van Dalen; Christine C Winterbourn; Anthony J Kettle
Mechanism of nitrite oxidation by eosinophil peroxidase: implications for oxidant production and nitration by eosinophils.
The Biochemical journal 2006;394(Pt 3):707-13.
2006: Fook-Choe Cheah; Brian A Darlow; Christine C Winterbourn
Association of hydrogen peroxide in exhaled breath condensates from infants with respiratory distress syndrome with the development of chronic lung disease.
Archives of disease in childhood. Fetal and neonatal edition 2006;91(2):F155.
2006: Alexander V Peskin; Christine C Winterbourn
Taurine chloramine is more selective than hypochlorous acid at targeting critical cysteines and inactivating creatine kinase and glyceraldehyde-3-phosphate dehydrogenase.
Free radical biology & medicine 2006;40(1):45-53.
2005: James W Baty; Mark Hampton; Christine C Winterbourn
Proteomic detection of hydrogen peroxide-sensitive thiol proteins in Jurkat cells.
The Biochemical journal 2005;389(Pt 3):785-95.
2005: George Kalogerakis; Arthur M Baker; Steve Christov; Kevin G Rowley; Karen Dwyer; Christine C Winterbourn; James D Best; Alicia J Jenkins
Oxidative stress and high-density lipoprotein function in Type I diabetes and end-stage renal disease.
Clinical science (London, England : 1979) 2005;108(6):497-506.
2005: Fook-Choe Cheah; Christine C Winterbourn; Brian A Darlow; Tessa J Mocatta; Margret C M Vissers
Nuclear factor kappaB activation in pulmonary leukocytes from infants with hyaline membrane disease: associations with chorioamnionitis and Ureaplasma urealyticum colonization.
Pediatric research 2005;57(5 Pt 1):616-23.
2005: Brian A Darlow; Hendrikje Buss; F McGill; L Fletcher; P Graham; Christine C Winterbourn
Vitamin C supplementation in very preterm infants: a randomised controlled trial.
Archives of disease in childhood. Fetal and neonatal edition 2005;90(2):F117-22.
2005: Fook-Choe Cheah; Mark Hampton; Brian A Darlow; Christine C Winterbourn; Margret C M Vissers
Detection of apoptosis by caspase-3 activation in tracheal aspirate neutrophils from premature infants: relationship with NF-kappaB activation.
Journal of leukocyte biology 2005;77(3):432-7.
2005: Alexander V Peskin; Robyn G Midwinter; David T Harwood; Christine C Winterbourn
Chlorine transfer between glycine, taurine, and histamine: reaction rates and impact on cellular reactivity.
Free radical biology & medicine 2005;38(3):397-405.
2005: Vanessa J Ellison; Tessa J Mocatta; Christine C Winterbourn; Brian A Darlow; Joseph J Volpe; Terrie E Inder
The relationship of CSF and plasma cytokine levels to cerebral white matter injury in the premature newborn.
Pediatric research 2005;57(2):282-6.
2005: Anthony J Kettle; Christine C Winterbourn
Do neutrophils produce ozone? An appraisal of current evidence.
BioFactors (Oxford, England) 2005;24(1-4):41-5.
2004: Alexander V Peskin; Robyn G Midwinter; David T Harwood; Christine C Winterbourn
Chlorine transfer between glycine, taurine, and histamine: reaction rates and impact on cellular reactivity.
Free radical biology & medicine 2004;37(10):1622-30.
2004: Christine C Winterbourn; Anthony J Kettle
Reactions of superoxide with myeloperoxidase and its products.
Japanese journal of infectious diseases 2004;57(5):S31-3.
2004: Robyn G Midwinter; Alexander V Peskin; Margret C M Vissers; Christine C Winterbourn
Extracellular oxidation by taurine chloramine activates ERK via the epidermal growth factor receptor.
The Journal of biological chemistry 2004;279(31):32205-11.
2004: Christine C Winterbourn; Helena N Parsons-Mair; Silvia Gebicki; Janusz M Gebicki; Michael J Davies
Requirements for superoxide-dependent tyrosine hydroperoxide formation in peptides.
The Biochemical journal 2004;381(Pt 1):241-8.
2004: Anthony J Kettle; Bruce M Clark; Christine C Winterbourn
Superoxide converts indigo carmine to isatin sulfonic acid: implications for the hypothesis that neutrophils produce ozone.
The Journal of biological chemistry 2004;279(18):18521-5.
2004: Rex Munday; Christine M Munday; Christine C Winterbourn
Inhibition of copper-catalyzed cysteine oxidation by nanomolar concentrations of iron salts.
Free radical biology & medicine 2004;36(6):757-64.
2004: Tessa J Mocatta; Christine C Winterbourn; Terrie E Inder; Brian A Darlow
The effect of gestational age and labour on markers of lipid and protein oxidation in cord plasma.
Free radical research 2004;38(2):185-91.
2003: Alexander V Peskin; Christine C Winterbourn
Histamine chloramine reactivity with thiol compounds, ascorbate, and methionine and with intracellular glutathione.
Free radical biology & medicine 2003;35(10):1252-60.
2003: Anna L P Chapman; Christine C Winterbourn; Stephen O Brennan; T William Jordan; Anthony J Kettle
Characterization of non-covalent oligomers of proteins treated with hypochlorous acid.
The Biochemical journal 2003;375(Pt 1):33-40.
2003: Christine C Winterbourn; Anthony J Kettle
Radical-radical reactions of superoxide: a potential route to toxicity.
Biochemical and biophysical research communications 2003;305(3):729-36.
2003: I Hendrikje Buss; Revathy Senthilmohan; Brian A Darlow; Nina Mogridge; Anthony J Kettle; Christine C Winterbourn
3-Chlorotyrosine as a marker of protein damage by myeloperoxidase in tracheal aspirates from preterm infants: association with adverse respiratory outcome.
Pediatric research 2003;53(3):455-62.
2003: Fook-Choe Cheah; Brian A Darlow; Christine C Winterbourn
Problems associated with collecting breath condensate for the measurement of exhaled hydrogen peroxide from neonates on respiratory support.
Biology of the neonate 2003;84(4):338-41.
2003: Christine C Winterbourn; Martin J D Bonham; Hendrikje Buss; Fikri M Abu-Zidan; John Windsor
Elevated protein carbonyls as plasma markers of oxidative stress in acute pancreatitis.
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2003;3(5):375-82.
2002: Christine C Winterbourn
Biological reactivity and biomarkers of the neutrophil oxidant, hypochlorous acid.
Toxicology 2002;181-182():223-7.
2002: James W Baty; Mark Hampton; Christine C Winterbourn
Detection of oxidant sensitive thiol proteins by fluorescence labeling and two-dimensional electrophoresis.
Proteomics 2002;2(9):1261-6.
2002: Terrie E Inder; Tessa J Mocatta; Brian A Darlow; Carole Spencer; Joseph J Volpe; Christine C Winterbourn
Elevated free radical products in the cerebrospinal fluid of VLBW infants with cerebral white matter injury.
Pediatric research 2002;52(2):213-8.
2002: Terrie E Inder; Tessa J Mocatta; Brian A Darlow; Carole Spencer; Revathy Senthilmohan; Christine C Winterbourn; Joseph J Volpe
Markers of oxidative injury in the cerebrospinal fluid of a premature infant with meningitis and periventricular leukomalacia.
The Journal of pediatrics 2002;140(5):617-21.
2002: Mark Hampton; Margret C M Vissers; Jacqueline I Keenan; Christine C Winterbourn
Oxidant-mediated phosphatidylserine exposure and macrophage uptake of activated neutrophils: possible impairment in chronic granulomatous disease.
Journal of leukocyte biology 2002;71(5):775-81.
2002: Dirk Roos; Christine C Winterbourn
Immunology. Lethal weapons.
Science (New York, N.Y.) 2002;296(5568):669-71.
2002: Mark Hampton; Ivan Stamenkovic; Christine C Winterbourn
Interaction with substrate sensitises caspase-3 to inactivation by hydrogen peroxide.
FEBS letters 2002;517(1-3):229-32.
2002: Anna L P Chapman; Mark Hampton; Revathy Senthilmohan; Christine C Winterbourn; Anthony J Kettle
Chlorination of bacterial and neutrophil proteins during phagocytosis and killing of Staphylococcus aureus.
The Journal of biological chemistry 2002;277(12):9757-62.
2002: Juliet M Pullar; Christine C Winterbourn; Margret C M Vissers
The effect of hypochlorous acid on the expression of adhesion molecules and activation of NF-kappaB in cultured human endothelial cells.
Antioxidants & redox signaling 2002;4(1):5-15.
2002: Mark Hampton; Christine C Winterbourn
Redox regulation of neutrophil function.
Antioxidants & redox signaling 2002;4(1):1-3.
2002: Christine C Winterbourn; Alexander V Peskin; Helena N Parsons-Mair
Thiol oxidase activity of copper, zinc superoxide dismutase.
The Journal of biological chemistry 2002;277(3):1906-11.
2002: I Hendrikje Buss; Christine C Winterbourn
Protein carbonyl measurement by ELISA.
Methods in molecular biology (Clifton, N.J.) 2002;186():123-8.
2001: Robyn G Midwinter; Margret C M Vissers; Christine C Winterbourn
Hypochlorous acid stimulation of the mitogen-activated protein kinase pathway enhances cell survival.
Archives of biochemistry and biophysics 2001;394(1):13-20.
2001: Anthony J Kettle; Christine C Winterbourn
A kinetic analysis of the catalase activity of myeloperoxidase.
Biochemistry 2001;40(34):10204-12.
2001: I Hendrikje Buss; F McGill; Brian A Darlow; Christine C Winterbourn
Vitamin C is reduced in human milk after storage.
Acta paediatrica (Oslo, Norway : 1992) 2001;90(7):813-5.
2001: Juliet M Pullar; Margret C M Vissers; Christine C Winterbourn
Glutathione oxidation by hypochlorous acid in endothelial cells produces glutathione sulfonamide as a major product but not glutathione disulfide.
The Journal of biological chemistry 2001;276(25):22120-5.
2001: KM Silvers; KB Sluis; Brian A Darlow; F McGill; R Stocker; Christine C Winterbourn
Limiting light-induced lipid peroxidation and vitamin loss in infant parenteral nutrition by adding multivitamin preparations to Intralipid.
Acta paediatrica (Oslo, Norway : 1992) 2001;90(3):242-9.
2001: Alexander V Peskin; Christine C Winterbourn
Kinetics of the reactions of hypochlorous acid and amino acid chloramines with thiols, methionine, and ascorbate.
Free radical biology & medicine 2001;30(5):572-9.
2001: KM Silvers; Brian A Darlow; Christine C Winterbourn
Lipid peroxide and hydrogen peroxide formation in parenteral nutrition solutions containing multivitamins.
JPEN. Journal of parenteral and enteral nutrition 2001;25(1):14-7.
2000: Juliet M Pullar; Margret C M Vissers; Christine C Winterbourn
Living with a killer: the effects of hypochlorous acid on mammalian cells.
IUBMB life 2000;50(4-5):259-66.
2000: Christine C Winterbourn; Anthony J Kettle
Biomarkers of myeloperoxidase-derived hypochlorous acid.
Free radical biology & medicine 2000;29(5):403-9.
2000: Christine C Winterbourn; T Chan; I Hendrikje Buss; Terrie E Inder; Nina Mogridge; Brian A Darlow
Protein carbonyls and lipid peroxidation products as oxidation markers in preterm infant plasma: associations with chronic lung disease and retinopathy and effects of selenium supplementation.
Pediatric research 2000;48(1):84-90.
2000: I Hendrikje Buss; Brian A Darlow; Christine C Winterbourn
Elevated protein carbonyls and lipid peroxidation products correlating with myeloperoxidase in tracheal aspirates from premature infants.
Pediatric research 2000;47(5):640-5.
2000: Anna L P Chapman; Revathy Senthilmohan; Christine C Winterbourn; Anthony J Kettle
Comparison of mono- and dichlorinated tyrosines with carbonyls for detection of hypochlorous acid modified proteins.
Archives of biochemistry and biophysics 2000;377(1):95-100.
2000: Christine J van Dalen; Christine C Winterbourn; Revathy Senthilmohan; Anthony J Kettle
Nitrite as a substrate and inhibitor of myeloperoxidase. Implications for nitration and hypochlorous acid production at sites of inflammation.
The Journal of biological chemistry 2000;275(16):11638-44.
2000: Brian A Darlow; Christine C Winterbourn; Terrie E Inder; PJ Graham; J E Harding; P J Weston; Nicola C Austin; D E Elder; Nina Mogridge; I Hendrikje Buss; KB Sluis
The effect of selenium supplementation on outcome in very low birth weight infants: a randomized controlled trial. The New Zealand Neonatal Study Group.
The Journal of pediatrics 2000;136(4):473-80.
2000: Alexander V Peskin; Christine C Winterbourn
A microtiter plate assay for superoxide dismutase using a water-soluble tetrazolium salt (WST-1).
Clinica chimica acta; international journal of clinical chemistry 2000;293(1-2):157-66.
2000: Christine C Winterbourn; I Hendrikje Buss; T P Chan; L D Plank; M A Clark; John Windsor
Protein carbonyl measurements show evidence of early oxidative stress in critically ill patients.
Critical care medicine 2000;28(1):143-9.
1999: Mark Hampton; Christine C Winterbourn
Methods for quantifying phagocytosis and bacterial killing by human neutrophils.
Journal of immunological methods 1999;232(1-2):15-22.
1999: Juliet M Pullar; Christine C Winterbourn; Margret C M Vissers
Loss of GSH and thiol enzymes in endothelial cells exposed to sublethal concentrations of hypochlorous acid.
The American journal of physiology 1999;277(4 Pt 2):H1505-12.
1999: Christine C Winterbourn; D Metodiewa
Reactivity of biologically important thiol compounds with superoxide and hydrogen peroxide.
Free radical biology & medicine 1999;27(3-4):322-8.
1999: Christine C Winterbourn; I Hendrikje Buss
Protein carbonyl measurement by enzyme-linked immunosorbent assay.
Methods in enzymology 1999;300():106-11.
1998: Mark Hampton; Anthony J Kettle; Christine C Winterbourn
Inside the neutrophil phagosome: oxidants, myeloperoxidase, and bacterial killing.
Blood 1998;92(9):3007-17.
1998: Terrie E Inder; PJ Graham; Christine C Winterbourn; Nicola C Austin; Brian A Darlow
Plasma vitamin A levels in the very low birthweight infant--relationship to respiratory outcome.
Early human development 1998;52(2):155-68.
1998: KM Silvers; Brian A Darlow; Christine C Winterbourn
Pharmacologic levels of heparin do not destabilize neonatal parenteral nutrition.
JPEN. Journal of parenteral and enteral nutrition 1998;22(5):311-4.
1998: M Vollebregt; Mark Hampton; Christine C Winterbourn
Activation of NF-kappaB in human neutrophils during phagocytosis of bacteria independently of oxidant generation.
FEBS letters 1998;432(1-2):40-4.
1998: AC Carr; J J van den Berg; Christine C Winterbourn
Differential reactivities of hypochlorous and hypobromous acids with purified Escherichia coli phospholipid: formation of haloamines and halohydrins.
Biochimica et biophysica acta 1998;1392(2-3):254-64.
1997: Christine J van Dalen; M W Whitehouse; Christine C Winterbourn; Anthony J Kettle
Thiocyanate and chloride as competing substrates for myeloperoxidase.
The Biochemical journal 1997;327 ( Pt 2)():487-92.
1997: KM Silvers; Christine C Winterbourn
The destabilisation of total parenteral nutrition by heparin. How real is the problem?
The New Zealand medical journal 1997;110(1053):386.
1997: AC Carr; Margret C M Vissers; N M Domigan; Christine C Winterbourn
Modification of red cell membrane lipids by hypochlorous acid and haemolysis by preformed lipid chlorohydrins.
Redox report : communications in free radical research 1997;3(5-6):263-71.
1997: Anthony J Kettle; Christine J van Dalen; Christine C Winterbourn
Peroxynitrite and myeloperoxidase leave the same footprint in protein nitration.
Redox report : communications in free radical research 1997;3(5-6):257-8.
1997: AC Carr; Christine C Winterbourn
Oxidation of neutrophil glutathione and protein thiols by myeloperoxidase-derived hypochlorous acid.
The Biochemical journal 1997;327 ( Pt 1)():275-81.
1997: Christine C Winterbourn; Stephen O Brennan
Characterization of the oxidation products of the reaction between reduced glutathione and hypochlorous acid.
The Biochemical journal 1997;326 ( Pt 1)():87-92.
1997: AC Carr; Christine C Winterbourn; J W Blunt; A J Phillips; Andrew D Abell
Nuclear magnetic resonance characterization of 6 alpha-chloro-5 beta-cholestane-3 beta,5-diol formed from the reaction of hypochlorous acid with cholesterol.
Lipids 1997;32(4):363-7.
1997: Brian A Darlow; KB Sluis; Terrie E Inder; Christine C Winterbourn
Endotracheal suctioning of the neonate: comparison of two methods as a source of mucus material for research.
Pediatric pulmonology 1997;23(3):217-21.
1997: Christine C Winterbourn; H Pichorner; Anthony J Kettle
Myeloperoxidase-dependent generation of a tyrosine peroxide by neutrophils.
Archives of biochemistry and biophysics 1997;338(1):15-21.
1997: Anthony J Kettle; C A Gedye; Christine C Winterbourn
Mechanism of inactivation of myeloperoxidase by 4-aminobenzoic acid hydrazide.
The Biochemical journal 1997;321 ( Pt 2)():503-8.
1997: Hendrikje Buss; T P Chan; KB Sluis; N M Domigan; Christine C Winterbourn
Protein carbonyl measurement by a sensitive ELISA method.
Free radical biology & medicine 1997;23(3):361-6.
1996: Terrie E Inder; Brian A Darlow; KB Sluis; Christine C Winterbourn; P Graham; K J Sanderson; B J Taylor
The correlation of elevated levels of an index of lipid peroxidation (MDA-TBA) with adverse outcome in the very low birthweight infant.
Acta paediatrica (Oslo, Norway : 1992) 1996;85(9):1116-22.
1996: Mark Hampton; Anthony J Kettle; Christine C Winterbourn
Involvement of superoxide and myeloperoxidase in oxygen-dependent killing of Staphylococcus aureus by neutrophils.
Infection and immunity 1996;64(9):3512-7.
1996: AC Carr; J J van den Berg; Christine C Winterbourn
Chlorination of cholesterol in cell membranes by hypochlorous acid.
Archives of biochemistry and biophysics 1996;332(1):63-9.
1996: AC Carr; Christine C Winterbourn; J J van den Berg
Peroxidase-mediated bromination of unsaturated fatty acids to form bromohydrins.
Archives of biochemistry and biophysics 1996;327(2):227-33.
1995: Christine C Winterbourn
Toxicity of iron and hydrogen peroxide: the Fenton reaction.
Toxicology letters 1995;82-83():969-74.
1995: H Pichorner; D Metodiewa; Christine C Winterbourn
Generation of superoxide and tyrosine peroxide as a result of tyrosyl radical scavenging by glutathione.
Archives of biochemistry and biophysics 1995;323(2):429-37.
1995: Brian A Darlow; Terrie E Inder; P J Graham; KB Sluis; T J Malpas; B J Taylor; Christine C Winterbourn
The relationship of selenium status to respiratory outcome in the very low birth weight infant.
Pediatrics 1995;96(2 Pt 1):314-9.
1995: Brian A Darlow; Terrie E Inder; KB Sluis; G Nuthall; Nina Mogridge; Christine C Winterbourn
Selenium status of New Zealand infants fed either a selenium supplemented or a standard formula.
Journal of paediatrics and child health 1995;31(4):339-44.
1995: Christine C Winterbourn; N M Domigan; J K Broom
Decreased thermal stability of red blood cell glu100-->gly superoxide dismutase from a family with amyotrophic lateral sclerosis.
FEBS letters 1995;368(3):449-51.
1995: Anthony J Kettle; C A Gedye; Mark Hampton; Christine C Winterbourn
Inhibition of myeloperoxidase by benzoic acid hydrazides.
The Biochemical journal 1995;308 ( Pt 2)():559-63.
1995: J Neuzil; Brian A Darlow; Terrie E Inder; KB Sluis; Christine C Winterbourn; R Stocker
Oxidation of parenteral lipid emulsion by ambient and phototherapy lights: potential toxicity of routine parenteral feeding.
The Journal of pediatrics 1995;126(5 Pt 1):785-90.
1995: V L Calder; N M Domigan; Peter M George; I M Donaldson; Christine C Winterbourn
Superoxide dismutase (glu100-->gly) in a family with inherited motor neuron disease: detection of mutant superoxide dismutase activity and the presence of heterodimers.
Neuroscience letters 1995;189(3):143-6.
1995: Mark Hampton; Christine C Winterbourn
Modification of neutrophil oxidant production with diphenyleneiodonium and its effect on bacterial killing.
Free radical biology & medicine 1995;18(4):633-9.
1995: Margret C M Vissers; Christine C Winterbourn
Oxidation of intracellular glutathione after exposure of human red blood cells to hypochlorous acid.
The Biochemical journal 1995;307 ( Pt 1)():57-62.
1995: Terrie E Inder; A C Carr; Christine C Winterbourn; Nicola C Austin; Brian A Darlow
Vitamin A and E status in very low birth weight infants: development of an improved parenteral delivery system.
The Journal of pediatrics 1995;126(1):128-31.
1995: Christine C Winterbourn; D Metodiewa
Reaction of superoxide with glutathione and other thiols.
Methods in enzymology 1995;251():81-6.
1994: Christine C Winterbourn; D Metodiewa
The reaction of superoxide with reduced glutathione.
Archives of biochemistry and biophysics 1994;314(2):284-90.
1994: C Thomas; AC Carr; Christine C Winterbourn
Free radical inactivation of rabbit muscle creatinine kinase: catalysis by physiological and hydrolyzed ICRF-187 (ICRF-198) iron chelates.
Free radical research 1994;21(6):387-97.
1994: A J Kettle; AC Carr; Christine C Winterbourn
Assays using horseradish peroxidase and phenolic substrates require superoxide dismutase for accurate determination of hydrogen peroxide production by neutrophils.
Free radical biology & medicine 1994;17(2):161-4.
1994: Anthony J Kettle; Christine C Winterbourn
Superoxide-dependent hydroxylation by myeloperoxidase.
The Journal of biological chemistry 1994;269(25):17146-51.
1994: Mark Hampton; Stephen T Chambers; Margret C M Vissers; Christine C Winterbourn
Bacterial killing by neutrophils in hypertonic environments.
The Journal of infectious diseases 1994;169(4):839-46.
1994: Mark Hampton; Margret C M Vissers; Christine C Winterbourn
A single assay for measuring the rates of phagocytosis and bacterial killing by neutrophils.
Journal of leukocyte biology 1994;55(2):147-52.
1994: KB Sluis; Brian A Darlow; M C Vissers; Christine C Winterbourn
Proteinase-antiproteinase balance in tracheal aspirates from neonates.
The European respiratory journal 1994;7(2):251-9.
1993: Anthony J Kettle; C A Gedye; Christine C Winterbourn
Superoxide is an antagonist of antiinflammatory drugs that inhibit hypochlorous acid production by myeloperoxidase.
Biochemical pharmacology 1993;45(10):2003-10.
1993: C Thomas; G F Vile; Christine C Winterbourn
The hydrolysis product of ICRF-187 promotes iron-catalysed hydroxyl radical production via the Fenton reaction.
Biochemical pharmacology 1993;45(10):1967-72.
1993: Christine C Winterbourn; AC Carr
Myeloperoxidase-dependent loss of malondialdehyde: a limitation for detecting neutrophil-mediated lipid peroxidation.
Archives of biochemistry and biophysics 1993;302(2):461-7.
1993: Christine C Winterbourn
Superoxide as an intracellular radical sink.
Free radical biology & medicine 1993;14(1):85-90.
1992: Christine C Winterbourn; D J Saville; Peter M George; T A Walmsley
Increase in selenium status of Christchurch adults associated with deregulation of the wheat market.
The New Zealand medical journal 1992;105(946):466-8.
1992: KB Sluis; Brian A Darlow; Peter M George; Nina Mogridge; B A Dolamore; Christine C Winterbourn
Selenium and glutathione peroxidase levels in premature infants in a low selenium community (Christchurch, New Zealand).
Pediatric research 1992;32(2):189-94.
1992: Anthony J Kettle; Christine C Winterbourn
Oxidation of hydroquinone by myeloperoxidase. Mechanism of stimulation by benzoquinone.
The Journal of biological chemistry 1992;267(12):8319-24.
1992: B A Dolamore; J Brown; Brian A Darlow; Peter M George; KB Sluis; Christine C Winterbourn
Selenium status of Christchurch infants and the effect of diet.
The New Zealand medical journal 1992;105(932):139-42.
1992: J Michaelis; Margret C M Vissers; Christine C Winterbourn
Different effects of hypochlorous acid on human neutrophil metalloproteinases: activation of collagenase and inactivation of collagenase and gelatinase.
Archives of biochemistry and biophysics 1992;292(2):555-62.
1992: J Michaelis; Margret C M Vissers; Christine C Winterbourn
Cleavage of alpha 1-antitrypsin by human neutrophil collagenase.
Matrix (Stuttgart, Germany). Supplement 1992;1():80-1.
1991: Anthony J Kettle; Christine C Winterbourn
Mechanism of inhibition of myeloperoxidase by anti-inflammatory drugs.
Biochemical pharmacology 1991;41(10):1485-92.
1991: Margret C M Vissers; Christine C Winterbourn
Oxidative damage to fibronectin. II. The effect of H2O2 and the hydroxyl radical.
Archives of biochemistry and biophysics 1991;285(2):357-64.
1991: Margret C M Vissers; Christine C Winterbourn
Oxidative damage to fibronectin. I. The effects of the neutrophil myeloperoxidase system and HOCl.
Archives of biochemistry and biophysics 1991;285(1):53-9.
1991: Christine C Winterbourn
Factors that influence the deoxyribose oxidation assay for Fenton reaction products.
Free radical biology & medicine 1991;11(4):353-60.
1991: Anthony J Kettle; Christine C Winterbourn
The influence of superoxide on the production of hypochlorous acid by human neutrophils.
Free radical research communications 1991;12-13 Pt 1():47-52.
1991: H P Monteiro; Christine C Winterbourn; A Stern
Tetravalent vanadium releases ferritin iron which stimulates vanadium-dependent lipid peroxidation.
Free radical research communications 1991;12-13 Pt 1():125-9.
1991: Christine C Winterbourn; G F Vile; H P Monteiro
Ferritin, lipid peroxidation and redox-cycling xenobiotics.
Free radical research communications 1991;12-13 Pt 1():107-14.
1990: Christine C Winterbourn; H P Monteiro; C F Galilee
Ferritin-dependent lipid peroxidation by stimulated neutrophils: inhibition by myeloperoxidase-derived hypochlorous acid but not by endogenous lactoferrin.
Biochimica et biophysica acta 1990;1055(2):179-85.
1990: J Michaelis; Margret C M Vissers; Christine C Winterbourn
Human neutrophil collagenase cleaves alpha 1-antitrypsin.
The Biochemical journal 1990;270(3):809-14.
1990: Anthony J Kettle; Christine C Winterbourn
Superoxide enhances hypochlorous acid production by stimulated human neutrophils.
Biochimica et biophysica acta 1990;1052(3):379-85.
1990: G F Vile; Christine C Winterbourn
dl-N,N'-dicarboxamidomethyl-N,N'-dicarboxymethyl-1,2-diaminopropane (ICRF-198) and d-1,2-bis(3,5-dioxopiperazine-1-yl)propane (ICRF-187) inhibition of Fe3+ reduction, lipid peroxidation, and CaATPase inactivation in heart microsomes exposed to adriamycin.
Cancer research 1990;50(8):2307-10.
1990: G Vile; Christine C Winterbourn
Thiol oxidation and inhibition of Ca-ATPase by adriamycin in rabbit heart microsomes.
Biochemical pharmacology 1990;39(4):769-74.
1990: A L Molloy; Christine C Winterbourn
Release of iron from phagocytosed Escherichia coli and uptake by neutrophil lactoferrin.
Blood 1990;75(4):984-9.
1990: Christine C Winterbourn; R Munday
Concerted action of reduced glutathione and superoxide dismutase in preventing redox cycling of dihydroxypyrimidines, and their role in antioxidant defence.
Free radical research communications 1990;8(4-6):287-93.
1989: H P Monteiro; Christine C Winterbourn
6-Hydroxydopamine releases iron from ferritin and promotes ferritin-dependent lipid peroxidation.
Biochemical pharmacology 1989;38(23):4177-82.
1989: Anthony J Kettle; Christine C Winterbourn
Influence of superoxide on myeloperoxidase kinetics measured with a hydrogen peroxide electrode.
The Biochemical journal 1989;263(3):823-8.
1989: H P Monteiro; Christine C Winterbourn
Release of iron from ferritin by divicine, isouramil, acid-hydrolyzed vicine, and dialuric acid and initiation of lipid peroxidation.
Archives of biochemistry and biophysics 1989;271(2):536-45.
1989: Christine C Winterbourn; R Munday
Glutathione-mediated redox cycling of alloxan. Mechanisms of superoxide dismutase inhibition and of metal-catalyzed OH. formation.
Biochemical pharmacology 1989;38(2):271-7.
1989: H P Monteiro; G F Vile; Christine C Winterbourn
An iron chelator is not required for reductive iron release from ferritin by radical generating systems.
Free radical research communications 1989;7(1):33-5.
1989: H P Monteiro; G F Vile; Christine C Winterbourn
Release of iron from ferritin by semiquinone, anthracycline, bipyridyl, and nitroaromatic radicals.
Free radical biology & medicine 1989;6(6):587-91.
1989: G F Vile; Christine C Winterbourn
Microsomal lipid peroxidation induced by adriamycin, epirubicin, daunorubicin and mitoxantrone: a comparative study.
Cancer chemotherapy and pharmacology 1989;24(2):105-8.
1988: H P Monteiro; Christine C Winterbourn
The superoxide-dependent transfer of iron from ferritin to transferrin and lactoferrin.
The Biochemical journal 1988;256(3):923-8.
1988: G F Vile; Christine C Winterbourn
Microsomal reduction of low-molecular-weight Fe3+ chelates and ferritin: enhancement by adriamycin, paraquat, menadione, and anthraquinone 2-sulfonate and inhibition by oxygen.
Archives of biochemistry and biophysics 1988;267(2):606-13.
1988: Anthony J Kettle; Christine C Winterbourn
The mechanism of myeloperoxidase-dependent chlorination of monochlorodimedon.
Biochimica et biophysica acta 1988;957(2):185-91.
1988: G F Vile; Christine C Winterbourn
Inhibition of adriamycin-promoted microsomal lipid peroxidation by beta-carotene, alpha-tocopherol and retinol at high and low oxygen partial pressures.
FEBS letters 1988;238(2):353-6.
1988: Anthony J Kettle; D F Sangster; J M Gebicki; Christine C Winterbourn
A pulse radiolysis investigation of the reactions of myeloperoxidase with superoxide and hydrogen peroxide.
Biochimica et biophysica acta 1988;956(1):58-62.
1988: G F Vile; Christine C Winterbourn
Adriamycin-dependent peroxidation of rat liver and heart microsomes catalysed by iron chelates and ferritin. Maximum peroxidation at low oxygen partial pressures.
Biochemical pharmacology 1988;37(15):2893-7.
1988: Margret C M Vissers; Peter M George; I C Bathurst; Stephen O Brennan; Christine C Winterbourn
Cleavage and inactivation of alpha 1-antitrypsin by metalloproteinases released from neutrophils.
The Journal of clinical investigation 1988;82(2):706-11.
1988: Anthony J Kettle; Christine C Winterbourn
Superoxide modulates the activity of myeloperoxidase and optimizes the production of hypochlorous acid.
The Biochemical journal 1988;252(2):529-36.
1988: Christine C Winterbourn; A L Molloy
Susceptibilities of lactoferrin and transferrin to myeloperoxidase-dependent loss of iron-binding capacity.
The Biochemical journal 1988;250(2):613-6.
1987: G F Vile; Christine C Winterbourn; H C Sutton
Radical-driven Fenton reactions: studies with paraquat, adriamycin, and anthraquinone 6-sulfonate and citrate, ATP, ADP, and pyrophosphate iron chelates.
Archives of biochemistry and biophysics 1987;259(2):616-26.
1987: Christine C Winterbourn; A Stern
Human red cells scavenge extracellular hydrogen peroxide and inhibit formation of hypochlorous acid and hydroxyl radical.
The Journal of clinical investigation 1987;80(5):1486-91.
1987: H C Sutton; G F Vile; Christine C Winterbourn
Radical driven Fenton reactions--evidence from paraquat radical studies for production of tetravalent iron in the presence and absence of ethylenediaminetetraacetic acid.
Archives of biochemistry and biophysics 1987;256(2):462-71.