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Alan Wiseman

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Publications

TOP 3
Alan Wiseman
p53 protein or BID protein select the route to either apoptosis (programmed cell death) or to cell cycle arrest opposing carcinogenesis after DNA damage by ROS.
Alan Wiseman
Crohn's disease leading to bowel cancer may be avoided by consumption of soya isoflavones: adjunct-chemotherapy with oxaliplatin.
Alan Wiseman
Oxygen-induced reperfusion-injury is caused by ROS: Amelioration is possible by recombinant-DNA antioxidant enzymes and mimics in selected tissues.

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All Publications

2006: Alan Wiseman
p53 protein or BID protein select the route to either apoptosis (programmed cell death) or to cell cycle arrest opposing carcinogenesis after DNA damage by ROS.
Medical hypotheses 2006;67(2):296-9.
2006: Alan Wiseman
Crohn's disease leading to bowel cancer may be avoided by consumption of soya isoflavones: adjunct-chemotherapy with oxaliplatin.
Medical hypotheses 2006;66(5):934-5.
2006: Alan Wiseman
Oxygen-induced reperfusion-injury is caused by ROS: Amelioration is possible by recombinant-DNA antioxidant enzymes and mimics in selected tissues.
Medical hypotheses 2006;66(2):329-31.
2006: Alan Wiseman
Methicillin-resistant Staphylococcus aureus has a beta-lactamase enzyme that can be plasmid-located: ejectable when under attack by adjunct antibiotics.
Medical hypotheses 2006;66(1):204-5.
2005: Alan Wiseman
Therapeutic-antagonists of oestrogens can be produced for cancer and other therapies using cytochromes P450 (CYP).
Medical hypotheses 2005;65(6):1088-90.
2005: Alan Wiseman
Oestrogen-receptors (ER) are likely to be promiscuous: wider role for oestrogens and mimics.
Medical hypotheses 2005;65(4):760-5.
2005: Alan Wiseman
p53 Protein is activated by Pin1: and also by Cu-SOD prion-like enzyme.
Medical hypotheses 2005;65(1):32-4.
2005: Alan Wiseman
Elimination of major side effects due to ROS of therapeuticals through biotransformation control of the 57 cytochromes P450 isoenzymes.
Medical hypotheses 2005;64(4):802-5.
2004: Alan Wiseman
Gene therapy for the circumvention of inborn errors of metabolism (IEM) caused by single-nucleotide-polymorphisms (SNPs).
Medical hypotheses 2004;63(5):810-2.
2004: Alan Wiseman
Dietary alkyl thiol free radicals (RSS) can be as toxic as reactive oxygen species (ROS).
Medical hypotheses 2004;63(4):667-70.
2004: Alan Wiseman
Greener vaccine production with GM yeasts.
Trends in biotechnology 2004;22(1):3.
2003: Alan Wiseman
Replacement of immobilised cell bioreactors by smaller immobilised enzyme bioreactors: unique-outcome predictability for cytochromes P450 isoforms?
Biotechnology letters 2003;25(19):1581-90.
2003: Alan Wiseman
Limitations of in silico predictability of specificity of co-immobilised cytochromes P450 and mimics in food-bioprocessing.
Biotechnology letters 2003;25(7):515-9.
2003: Alan Wiseman; Len Woods
Safe choice of metals in food bioprocess enzyme-mimicry?
Trends in biotechnology 2003;21(1):7-8.
2002: Alan Wiseman; Len Woods
Can "real-lab" supersede "virtual-ligand" promises?
Trends in pharmacological sciences 2002;23(6):261.
2002: Alan Wiseman; Len Woods
Is incorporating CO2 'green'?
Biologist (London, England) 2002;49(1):4.
2002: Alan Wiseman; Tim Ridgway; Peter S Goldfarb; Len Woods
Are food and environmental toxicants 'overdetected' by bioassay?
Trends in biotechnology 2002;20(1):13-5.
2001: Alan Wiseman; Len Woods
Tankers for the memory.
Biologist (London, England) 2001;48(6):248.
2001: Alan Wiseman; Peter S Goldfarb; Len Woods; Tim Ridgway
Aquatic ecorehabilitation biotechnology.
Trends in biotechnology 2001;19(12):490.
2001: Alan Wiseman; P S Goldfard; Len Woods; Tim Ridgway
Novel biocatalytic enzymes by directed evolution.
Trends in biotechnology 2001;19(10):382.
2001: Alan Wiseman; Peter S Goldfarb
Do'fail-clean' ecostrategies deliver 'fail-safe' outcomes?
Trends in biotechnology 2001;19(8):287.
2001: Alan Wiseman; Len Woods; T Ridgeway
Bioprocessing to generate 'multifunctional' foods?
Trends in biotechnology 2001;19(3):89-90.
2001: Alan Wiseman; Peter S Goldfarb
Biomonitoring, ecoextrapolation and then bioremediation for ecorestoration?
Trends in biotechnology 2001;19(1):7-8.
2000: Alan Wiseman; Peter S Goldfarb; Tim Ridgway; Helen Wiseman
Biomarkers, bioindicators or ecotranslators to biomonitor oestrogen mimics?
Trends in biotechnology 2000;18(1):1.
1999: Alan Wiseman; Tim Ridgway; Helen Wiseman
Bioclean effluents or bioclean products?
Trends in biotechnology 1999;17(12):461.
1999: Alan Wiseman; Peter S Goldfarb; Tim Ridgway; Helen Wiseman
Xenoestrogens and phytoestrogens: bioremediation or biomonitoring?
Trends in biotechnology 1999;17(2):43.
1998: Alan Wiseman; Peter S Goldfarb; Tim Ridgway; Helen Wiseman
Biomolecular site-recognition in the prediction of environmental oestrogen mimicry.
Biochemical Society transactions 1998;26(4):670-4.
1996: Alan Wiseman; Peter S Goldfarb
Is there an optimal membrane protein content determined by membrane stability to lipid peroxidation? Disease and ageing consideration.
Biochemical Society transactions 1996;24(3):376S.
1996: E Straghan; G Sharma; Peter S Goldfarb; Alan Wiseman
Identification of pro-oxidant or antioxidant characteristics of proteins and enzymes in membranes; use of liposome-entrapped proteins and other thiol-containing compounds.
Biochemical Society transactions 1996;24(3):375S.
1995: M Winkler; B Underwood; Alan Wiseman
Notable increase in content of cytochrome P-450 enzymes in Saccharomyces cerevisiae in repetitive alternating culturing.
Biochemical Society transactions 1995;23(3):499S.
1995: A Riedl; M Anderton; Ziba Shamsi; Peter S Goldfarb; Alan Wiseman
Structural modulation of lipid peroxidation by the proteins within membranes: model protein studies with liposomes.
Biochemical Society transactions 1995;23(2):251S.
1993: Alan Wiseman
Genetically-engineered mammalian cytochromes P-450 from yeasts--potential applications.
Trends in biotechnology 1993;11(4):131-6.
1990: D J King; Alan Wiseman; P A Chalk; C J Coulson
An assay for lanosterol 14 alpha-demethylase from Saccharomyces cerevisiae.
Biochemical Society transactions 1990;18(5):1001-2.
1990: L R Jafelice; Alan Wiseman; Peter S Goldfarb
Production of lignin peroxidase by Phanerochaete chrysoporium in medium containing molasses.
Biochemical Society transactions 1990;18(4):642-3.
1990: L R Jafelice; Alan Wiseman; Peter S Goldfarb
Exocellular and intracellular beta-glucosidase produced in ligninolytic culture of Phanerochaete chrysosporium.
Biochemical Society transactions 1990;18(4):644-5.
1989: J A Spry; D R Livingstone; Alan Wiseman; G Gordon Gibson; Peter S Goldfarb
Cytochrome P-450 gene expression in the common mussel Mytilus edulis.
Biochemical Society transactions 1989;17(6):1013-4.