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Susanne Wisén

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Chemicals & Drugs

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Protein Binding

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Publications

TOP 3
Sidhartha M Chafekar; AnaLisa Echeverria; Christopher G Evans; Jason E Gestwicki; Leah N Makley; Andrea D Thompson; Gladis M Walter; Susanne Wisén; Martin L Duennwald
Pharmacological tuning of heat shock protein 70 modulates polyglutamine toxicity and aggregation.
Gladis M Walter; Susanne Wisén; Anuj Kumar; Matthew C Smith; venkatesha basrur; Martin L Duennwald; Kojo Seys John Elenitoba-Johnson; Jason E Gestwicki
Ordered assembly of heat shock proteins, Hsp26, Hsp70, Hsp90, and Hsp104, on expanded polyglutamine fragments revealed by chemical probes.
Susanne Wisén; Eric B Bertelsen; Andrea D Thompson; Srikanth Patury; Peter Ung; Lyra Chang; Christopher G Evans; Gladis M Walter; Peter Wipf; Heather A Carlson; Jeffrey L Brodsky; Erik R P Zuiderweg; Jason E Gestwicki
Binding of a small molecule at a protein-protein interface regulates the chaperone activity of hsp70-hsp40.

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All Publications

2012: Sidhartha M Chafekar; AnaLisa Echeverria; Christopher G Evans; Jason E Gestwicki; Leah N Makley; Andrea D Thompson; Gladis M Walter; Susanne Wisén; Martin L Duennwald
Pharmacological tuning of heat shock protein 70 modulates polyglutamine toxicity and aggregation.
ACS chemical biology 2012;7(9):1556-64.
2011: Gladis M Walter; Susanne Wisén; Anuj Kumar; Matthew C Smith; venkatesha basrur; Martin L Duennwald; Kojo Seys John Elenitoba-Johnson; Jason E Gestwicki
Ordered assembly of heat shock proteins, Hsp26, Hsp70, Hsp90, and Hsp104, on expanded polyglutamine fragments revealed by chemical probes.
The Journal of biological chemistry 2011;286(47):40486-93.
2010: Susanne Wisén; Eric B Bertelsen; Andrea D Thompson; Srikanth Patury; Peter Ung; Lyra Chang; Christopher G Evans; Gladis M Walter; Peter Wipf; Heather A Carlson; Jeffrey L Brodsky; Erik R P Zuiderweg; Jason E Gestwicki
Binding of a small molecule at a protein-protein interface regulates the chaperone activity of hsp70-hsp40.
ACS chemical biology 2010;5(6):611-22.
2008: Susanne Wisén; Jason E Gestwicki
Identification of small molecules that modify the protein folding activity of heat shock protein 70.
Analytical biochemistry 2008;374(2):371-7.
2008: Lyra Chang; Eric B Bertelsen; Susanne Wisén; Erik M Larsen; Erik R P Zuiderweg; Jason E Gestwicki
High-throughput screen for small molecules that modulate the ATPase activity of the molecular chaperone DnaK.
Analytical biochemistry 2008;372(2):167-76.
2008: Susanne Wisén; John Androsavich; Christopher G Evans; Lyra Chang; Jason E Gestwicki
Chemical modulators of heat shock protein 70 (Hsp70) by sequential, microwave-accelerated reactions on solid phase.
Bioorganic & medicinal chemistry letters 2008;18(1):60-5.
2006: Christopher G Evans; Susanne Wisén; Jason E Gestwicki
Heat shock proteins 70 and 90 inhibit early stages of amyloid beta-(1-42) aggregation in vitro.
The Journal of biological chemistry 2006;281(44):33182-91.
2004: Susanne Wisén; Birgitta Bergman; Bengt Mannervik
Mutagenesis of the cysteine residues in the transcription factor NtcA from Anabaena PCC 7120 and its effects on DNA binding in vitro.
Biochimica et biophysica acta 2004;1679(2):156-63.
2004: Susanne Wisén; Tove Sjögren; Birgit Olin; Bengt Mannervik
Purification, crystallization and preliminary X-ray data of the transcription factor NtcA from the cyanobacterium Anabaena PCC 7120.
Acta crystallographica. Section D, Biological crystallography 2004;60(Pt 5):923-5.
2000: F Jiang; Susanne Wisén; Mikael Widersten; Birgitta Bergman; Bengt Mannervik
Examination of the transcription factor NtcA-binding motif by in vitro selection of DNA sequences from a random library.
Journal of molecular biology 2000;301(4):783-93.
1999: Susanne Wisén; F Jiang; Birgitta Bergman; Bengt Mannervik
Expression and purification of the transcription factor NtcA from the cyanobacterium Anabaena PCC 7120.
Protein expression and purification 1999;17(3):351-7.
1998: NC Bergenhem; M Hallberg; Susanne Wisén
Molecular characterization of the human carbonic anhydrase-related protein (HCA-RP VIII).
Biochimica et biophysica acta 1998;1384(2):294-8.