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David Wisniewski

Research Profile

Anatomy

Disorders

Leukemia, Myelogenous, Chronic, BCR-ABL Positive

Chemicals & Drugs

Procedures

Physiology

Phenomena

Phosphorylation

Co-author Network

Publications

TOP 3
Xiquan Liang; Mahbod Hajivandi; Darren R Veach; David Wisniewski; Bayard Clarkson; Marilyn D Resh; Marshall pope
Quantification of change in phosphorylation of BCR-ABL kinase and its substrates in response to Imatinib treatment in human chronic myelogenous leukemia cells.
Bayard Clarkson; Annabel Strife; David Wisniewski; Caryl L Lambek; Chongyuan Liu
Chronic myelogenous leukemia as a paradigm of early cancer and possible curative strategies.
Annabel Strife; David Wisniewski; Chongyuan Liu; Caryl L Lambek; Zbigniew Darzynkiewicz; Richard T Silver; Bayard Clarkson
Direct evidence that Bcr-Abl tyrosine kinase activity disrupts normal synergistic interactions between Kit ligand and cytokines in primary primitive progenitor cells.

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All Publications

2006: Xiquan Liang; Mahbod Hajivandi; Darren R Veach; David Wisniewski; Bayard Clarkson; Marilyn D Resh; Marshall pope
Quantification of change in phosphorylation of BCR-ABL kinase and its substrates in response to Imatinib treatment in human chronic myelogenous leukemia cells.
Proteomics 2006;6(16):4554-64.
2003: Bayard Clarkson; Annabel Strife; David Wisniewski; Caryl L Lambek; Chongyuan Liu
Chronic myelogenous leukemia as a paradigm of early cancer and possible curative strategies.
Leukemia 2003;17(7):1211-62.
2003: Annabel Strife; David Wisniewski; Chongyuan Liu; Caryl L Lambek; Zbigniew Darzynkiewicz; Richard T Silver; Bayard Clarkson
Direct evidence that Bcr-Abl tyrosine kinase activity disrupts normal synergistic interactions between Kit ligand and cytokines in primary primitive progenitor cells.
Molecular cancer research : MCR 2003;1(3):176-85.
2002: David Wisniewski; Caryl L Lambek; Chongyuan Liu; Annabel Strife; Darren R Veach; Bhushan Nagar; Matthew Adam Young; Thomas Schindler; William G Bornmann; Joseph R Bertino; John Kuriyan; Bayard Clarkson
Characterization of potent inhibitors of the Bcr-Abl and the c-kit receptor tyrosine kinases.
Cancer research 2002;62(15):4244-55.
2002: Xiquan Liang; David Wisniewski; Annabel Strife; Bayard Clarkson; Marilyn D Resh
Phosphatidylinositol 3-kinase and Src family kinases are required for phosphorylation and membrane recruitment of Dok-1 in c-Kit signaling.
The Journal of biological chemistry 2002;277(16):13732-8.
2000: N M Dunant; David Wisniewski; Annabel Strife; Bayard Clarkson; Marilyn D Resh
The phosphatidylinositol polyphosphate 5-phosphatase SHIP1 associates with the dok1 phosphoprotein in bcr-Abl transformed cells.
Cellular signalling 2000;12(5):317-26.
2000: Ellin Berman; Suresh C Jhanwar; M McBride; Annabel Strife; David Wisniewski; Caryl L Lambek; Bayard Clarkson
Characterization of two novel sublines established from a human megakaryoblastic leukemia cell line transfected with p210(BCR-ABL).
Leukemia research 2000;24(4):289-97.
1999: David Wisniewski; Annabel Strife; S Swendeman; H Erdjument-Bromage; S Geromanos; W M Kavanaugh; Paul Tempst; Bayard Clarkson
A novel SH2-containing phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase (SHIP2) is constitutively tyrosine phosphorylated and associated with src homologous and collagen gene (SHC) in chronic myelogenous leukemia progenitor cells.
Blood 1999;93(8):2707-20.
1998: Antonio Di Cristofano; N Carpino; N Dunant; G Friedland; Ryuji Kobayashi; Annabel Strife; David Wisniewski; Bayard Clarkson; Pier Paolo Pandolfi; Marilyn D Resh
Molecular cloning and characterization of p56dok-2 defines a new family of RasGAP-binding proteins.
The Journal of biological chemistry 1998;273(9):4827-30.
1997: Bayard Clarkson; Annabel Strife; David Wisniewski; Caryl L Lambek; N Carpino
New understanding of the pathogenesis of CML: a prototype of early neoplasia.
Leukemia 1997;11(9):1404-28.
1997: N Carpino; David Wisniewski; Annabel Strife; D Marshak; Ryuji Kobayashi; Bruce Stillman; Bayard Clarkson
p62(dok): a constitutively tyrosine-phosphorylated, GAP-associated protein in chronic myelogenous leukemia progenitor cells.
Cell 1997;88(2):197-204.
1996: David Wisniewski; Annabel Strife; Bayard Clarkson
c-kit ligand stimulates tyrosine phosphorylation of the c-Cbl protein in human hematopoietic cells.
Leukemia 1996;10(9):1436-42.
1996: David Wisniewski; Annabel Strife; Ellin Berman; Bayard Clarkson
c-kit ligand stimulates tyrosine phosphorylation of a similar pattern of phosphotyrosyl proteins in primary primitive normal hematopoietic progenitors that are constitutively phosphorylated in comparable primitive progenitors in chronic phase chronic myelogenous leukemia.
Leukemia 1996;10(2):229-37.
1994: David Wisniewski; Annabel Strife; D Wojciechowicz; C Lambek; Bayard Clarkson
A 62-kilodalton tyrosine phosphoprotein constitutively present in primary chronic phase chronic myelogenous leukemia enriched lineage negative blast populations.
Leukemia 1994;8(4):688-93.
1993: Annabel Strife; A Perez; C Lambek; David Wisniewski; S Bruno; Zbigniew Darzynkiewicz; Bayard Clarkson
Differences in the composition and in the efficiency of red cell production of normal and CML erythroid progenitor populations are highlighted by response to human c-kit ligand.
Leukemia research 1993;17(9):799-807.
1993: Annabel Strife; A Perez; C Lambek; David Wisniewski; S Bruno; Zbigniew Darzynkiewicz; Bayard Clarkson
Characterization of lineage-negative blast subpopulations derived from normal and chronic myelogenous leukemia bone marrows and determination of their responsiveness to human c-kit ligand.
Cancer research 1993;53(2):401-9.
1993: Bayard Clarkson; Annabel Strife; A Perez; C Lambek; David Wisniewski
Integration of molecular and biological abnormalities in quest for selective treatment of chronic myelogenous leukemia (CML).
Leukemia & lymphoma 1993;11 Suppl 2():81-100.
1992: Coralia I Rivas; David Wisniewski; Annabel Strife; A Perez; C Lambek; S Bruno; Zbigniew Darzynkiewicz; Bayard Clarkson
Constitutive expression of p53 protein in enriched normal human marrow blast cell populations.
Blood 1992;79(8):1982-6.
1991: Ellin Berman; Annabel Strife; David Wisniewski; S Desai; S Gulati; Suresh C Jhanwar; Bayard Clarkson
Duration of the preclinical phase of chronic myelogenous leukemia: a case report.
Blood 1991;78(11):2969-72.
1991: David Wisniewski; Annabel Strife; Bayard Clarkson
Co-detection of chimeric bcr/abl (target) and beta-actin (control) messenger RNA in individual CFU-GM colonies derived from CML patients using the polymerase chain reaction.
Leukemia research 1991;15(9):867-74.
1989: David Wisniewski; Annabel Strife; Z Arlin; R Knowles; C Lambek; S Gulati; B McHendry; S McKenzie; Bayard Clarkson
Analysis of the individual and combined reactivities of monoclonal antibodies H25, H366, and MY9 with normal progenitor cells and blast cells from patients with acute myeloblastic leukemia.
Leukemia 1989;3(6):446-52.
1989: Jens Atzpodien; C Bührer; S C Gulati; David Wisniewski; S Oz; Holger Kirchner; Thomas Benter; H Poliwoda; Karl Welte; Bayard Clarkson
Induction of nonspecific cell-mediated cytotoxicity: a multisignal event and its cellular regulation.
Haematology and blood transfusion 1989;32():273-80.
1989: A Körfer; Holger Kirchner; C Schneekloth; C Bührer; David Wisniewski; S Gulati; Bayard Clarkson; R Knowles; H Poliwoda; Jens Atzpodien
Immunophenotypic demonstration of two natural killer surface markers, H25 and H366, on fresh human leukemic cells.
Acta haematologica 1989;82(4):193-6.
1988: Chihiro Shimazaki; David Wisniewski; David A Scheinberg; Jens Atzpodien; Annabel Strife; S Gulati; J Fried; R Wisniewolski; C Y Wang; Bayard Clarkson
Elimination of myeloma cells from bone marrow by using monoclonal antibodies and magnetic immunobeads.
Blood 1988;72(4):1248-54.
1988: Annabel Strife; C Lambek; David Wisniewski; M Wachter; S C Gulati; Bayard Clarkson
Discordant maturation as the primary biological defect in chronic myelogenous leukemia.
Cancer research 1988;48(4):1035-41.
1988: Chihiro Shimazaki; Jens Atzpodien; David Wisniewski; S C Gulati; Jonathan E Kolitz; J Fried; Bayard Clarkson
Cell-mediated toxicity of interleukin-2-activated lymphocytes against autologous and allogeneic human myeloma cells.
Acta haematologica 1988;80(4):203-9.
1987: David Wisniewski; Annabel Strife; J Atzpodien; Bayard Clarkson
Effects of recombinant human tumor necrosis factor on highly enriched hematopoietic progenitor cell populations from normal human bone marrow and peripheral blood and bone marrow from patients with chronic myeloid leukemia.
Cancer research 1987;47(18):4788-94.
1987: Annabel Strife; C Lambek; David Wisniewski; S Gulati; J C Gasson; D W Golde; K Welte; J L Gabrilove; Bayard Clarkson
Activities of four purified growth factors on highly enriched human hematopoietic progenitor cells.
Blood 1987;69(5):1508-23.
1987: David Wisniewski; R Knowles; M Wachter; Annabel Strife; Bayard Clarkson
Expression of two natural killer cell antigens, H-25 and H-366, by human immature myeloid cells and by erythroid and granulocytic/monocytic colony-forming units.
Blood 1987;69(2):419-29.
1987: Jens Atzpodien; David Wisniewski; S Gulati; K Welte; R Knowles; Bayard Clarkson
Interleukin-2- and mitogen-activated NK-like killer cells from highly purified human peripheral blood T cell (CD3+ N901-) cultures.
Natural immunity and cell growth regulation 1987;6(3):129-40.
1985: David Wisniewski; Annabel Strife; M Wachter; Bayard Clarkson
Regulation of human peripheral blood erythroid burst-forming unit growth by T lymphocytes and T lymphocyte subpopulations defined by OKT4 and OKT8 monoclonal antibodies.
Blood 1985;65(2):456-63.
1983: Annabel Strife; C Lambek; David Wisniewski; Z Arlin; Howard T Thaler; Bayard Clarkson
Proliferative potential of subpopulations of granulocyte-macrophage progenitor cells in normal subjects and chronic myelogenous leukemia patients.
Blood 1983;62(2):389-97.
1982: David Wisniewski; C Platsoucas; Annabel Strife; C Lambek; Bayard Clarkson
Enrichment of hematopoietic progenitor cells (CFUC and BFUE) from human peripheral blood.
Experimental hematology 1982;10(10):817-29.
1982: T Goto; M Nishikori; Z Arlin; T Gee; Sanford J. Kempin; J Burchenal; Annabel Strife; David Wisniewski; C Lambek; C Little; Suresh C Jhanwar; Raju S K Chaganti; Bayard Clarkson
Growth characteristics of leukemic and normal hematopoietic cells in Ph' + chronic myelogenous leukemia and effects of intensive treatment.
Blood 1982;59(4):793-808.