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Manuela Wissler

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Chemicals & Drugs

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Céline Charvet; Douglas R Green; Wei Gu; Silke E Lindner; Christoph Borner; Martin Brandenburg; Prisca Brauns-Schubert; Bernhard Breit; Steven B McMahon; Hestia Mellert; Florian C Sigloch; Yi Tang; Shang-Jui Wang; Manuela Wissler; Ulrich Maurer
Phosphorylation of Tip60 by GSK-3 determines the induction of PUMA and apoptosis by p53.
Kerstin Schwarzwaelder; Steven J Howe; Manfred Schmidt; Martijn Brugman; Annette Deichmann; Hanno Glimm; Sonja Schmidt; Claudia Prinz; Manuela Wissler; Douglas J S King; Fang Zhang; Kathryn L Parsley; Kimberly C Gilmour; Joanna Sinclair; Jinhua Bayford; Rachel Peraj; Karin Pike-Overzet; Frank Staal; Dick de Ridder; Christine Kinnon; Ulrich Abel; Gerard Wagemaker; H Bobby Gaspar; Adrian J Thrasher; Christof von Kalle
Gammaretrovirus-mediated correction of SCID-X1 is associated with skewed vector integration site distribution in vivo.
Hanno Glimm; Manfred Schmidt; Marlene Fischer; Kerstin Schwarzwaelder; Manuela Wissler; Silke Klingenberg; Claudia Prinz; Cornelius F Waller; Winand Lange; Connie J Eaves; Christof von Kalle
Efficient marking of human cells with rapid but transient repopulating activity in autografted recipients.

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All Publications

2011: Céline Charvet; Douglas R Green; Wei Gu; Silke E Lindner; Christoph Borner; Martin Brandenburg; Prisca Brauns-Schubert; Bernhard Breit; Steven B McMahon; Hestia Mellert; Florian C Sigloch; Yi Tang; Shang-Jui Wang; Manuela Wissler; Ulrich Maurer
Phosphorylation of Tip60 by GSK-3 determines the induction of PUMA and apoptosis by p53.
Molecular cell 2011;42(5):584-96.
2007: Kerstin Schwarzwaelder; Steven J Howe; Manfred Schmidt; Martijn Brugman; Annette Deichmann; Hanno Glimm; Sonja Schmidt; Claudia Prinz; Manuela Wissler; Douglas J S King; Fang Zhang; Kathryn L Parsley; Kimberly C Gilmour; Joanna Sinclair; Jinhua Bayford; Rachel Peraj; Karin Pike-Overzet; Frank Staal; Dick de Ridder; Christine Kinnon; Ulrich Abel; Gerard Wagemaker; H Bobby Gaspar; Adrian J Thrasher; Christof von Kalle
Gammaretrovirus-mediated correction of SCID-X1 is associated with skewed vector integration site distribution in vivo.
The Journal of clinical investigation 2007;117(8):2241-9.
2005: Hanno Glimm; Manfred Schmidt; Marlene Fischer; Kerstin Schwarzwaelder; Manuela Wissler; Silke Klingenberg; Claudia Prinz; Cornelius F Waller; Winand Lange; Connie J Eaves; Christof von Kalle
Efficient marking of human cells with rapid but transient repopulating activity in autografted recipients.
Blood 2005;106(3):893-8.
2005: Manfred Schmidt; Salima Hacein-Bey-Abina; Manuela Wissler; Frédérique Carlier; Annick Lim; Claudia Prinz; Hanno Glimm; Isabelle Andre-Schmutz; Christophe Hue; Alexandrine Garrigue; Françoise Le Deist; Chantal Lagresle; Alain Fischer; Marina Cavazzana-Calvo; Christof von Kalle
Clonal evidence for the transduction of CD34+ cells with lymphomyeloid differentiation potential and self-renewal capacity in the SCID-X1 gene therapy trial.
Blood 2005;105(7):2699-706.
2003: Manfred Schmidt; Hanno Glimm; Manuela Wissler; Gesa Hoffmann; Karin Olsson; Stephanie Sellers; Denise A Carbonaro; John F Tisdale; Cordula Leurs; Helmut Hanenberg; Cynthia E Dunbar; Hans-Peter Kiem; Stefan Karlsson; Donald B Kohn; David Williams; Christof von Kalle
Efficient characterization of retro-, lenti-, and foamyvector-transduced cell populations by high-accuracy insertion site sequencing.
Annals of the New York Academy of Sciences 2003;996():112-21.
2003: Cordula Leurs; Michael Jansen; Karen E Pollok; Martin Heinkelein; Manfred Schmidt; Manuela Wissler; Dirk Lindemann; Christof von Kalle; Axel Rethwilm; David A Williams; Helmut Hanenberg
Comparison of three retroviral vector systems for transduction of nonobese diabetic/severe combined immunodeficiency mice repopulating human CD34+ cord blood cells.
Human gene therapy 2003;14(6):509-19.
2003: Manfred Schmidt; Denise A Carbonaro; Carsten Speckmann; Manuela Wissler; John Bohnsack; Melissa Elder; Bruce Aronow; Jan A Nolta; Donald B Kohn; Christof von Kalle
Clonality analysis after retroviral-mediated gene transfer to CD34+ cells from the cord blood of ADA-deficient SCID neonates.
Nature medicine 2003;9(4):463-8.
2002: Manfred Schmidt; Philipp Zickler; Gesa Hoffmann; Sebastian Haas; Manuela Wissler; Arne Muessig; John F Tisdale; Ken Kuramoto; Robert G Andrews; Tong Wu; Hans-Peter Kiem; Cynthia E Dunbar; Christof von Kalle
Polyclonal long-term repopulating stem cell clones in a primate model.
Blood 2002;100(8):2737-43.
2001: Martina Schmidt; Gesa Hoffmann; Manuela Wissler; N Lemke; A Müssig; Hanno Glimm; David A Williams; S Ragg; C U Hesemann; Christof von Kalle
Detection and direct genomic sequencing of multiple rare unknown flanking DNA in highly complex samples.
Human gene therapy 2001;12(7):743-9.
1999: E Stoecklin; Manuela Wissler; D Schaetzle; Edith Pfitzner; Bernd Groner
Interactions in the transcriptional regulation exerted by Stat5 and by members of the steroid hormone receptor family.
The Journal of steroid biochemistry and molecular biology 1999;69(1-6):195-204.
1998: Edith Pfitzner; R Jähne; Manuela Wissler; E Stoecklin; Bernd Groner
p300/CREB-binding protein enhances the prolactin-mediated transcriptional induction through direct interaction with the transactivation domain of Stat5, but does not participate in the Stat5-mediated suppression of the glucocorticoid response.
Molecular endocrinology (Baltimore, Md.) 1998;12(10):1582-93.
1997: S Berchtold; Richard Moriggl; Fabrice Gouilleux; O Silvennoinen; C Beisenherz; Edith Pfitzner; Manuela Wissler; E Stöcklin; Bernd Groner
Cytokine receptor-independent, constitutively active variants of STAT5.
The Journal of biological chemistry 1997;272(48):30237-43.
1997: E Stoecklin; Manuela Wissler; Richard Moriggl; Bernd Groner
Specific DNA binding of Stat5, but not of glucocorticoid receptor, is required for their functional cooperation in the regulation of gene transcription.
Molecular and cellular biology 1997;17(11):6708-16.
1997: Richard Moriggl; S Berchtold; Karlheinz Friedrich; G J Standke; W Kammer; M Heim; Manuela Wissler; E Stöcklin; Fabrice Gouilleux; Bernd Groner
Comparison of the transactivation domains of Stat5 and Stat6 in lymphoid cells and mammary epithelial cells.
Molecular and cellular biology 1997;17(7):3663-78.
1996: E Stöcklin; Manuela Wissler; Fabrice Gouilleux; Bernd Groner
Functional interactions between Stat5 and the glucocorticoid receptor.
Nature 1996;383(6602):726-8.