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Agnieszka Witkiewicz

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Matias E Valsecchi; Agnieszka Witkiewicz; Misti Coronel; Charles M Intenzo; Sung M Kim; Takami Sato
Somatostatin receptor scintigraphy in patients with metastatic uveal melanoma.
Chellappagounder Thangavel; Agnieszka Witkiewicz; Meng Lim; Sankar Addya; Ettickan Boopathi; Adam Ertel; Paolo Fortina; Erik S Knudsen
Regulation of miR106b cluster through the RB pathway: mechanism and functional targets.
Jeffry L Dean; Theresa E Hickey; A Kathleen McClendon; Wayne D Tilley; Agnieszka Witkiewicz; Lisa M Butler; Erik S Knudsen
Therapeutic response to CDK4/6 inhibition in breast cancer defined by ex vivo analyses of human tumors.

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2013: Matias E Valsecchi; Agnieszka Witkiewicz; Misti Coronel; Charles M Intenzo; Sung M Kim; Takami Sato
Somatostatin receptor scintigraphy in patients with metastatic uveal melanoma.
Melanoma research 2013;23(1):33-9.
2013: Chellappagounder Thangavel; Agnieszka Witkiewicz; Meng Lim; Sankar Addya; Ettickan Boopathi; Adam Ertel; Paolo Fortina; Erik S Knudsen
Regulation of miR106b cluster through the RB pathway: mechanism and functional targets.
Cell cycle (Georgetown, Tex.) 2013;12(1):98-111.
2012: Jeffry L Dean; Theresa E Hickey; A Kathleen McClendon; Wayne D Tilley; Agnieszka Witkiewicz; Lisa M Butler; Erik S Knudsen
Therapeutic response to CDK4/6 inhibition in breast cancer defined by ex vivo analyses of human tumors.
Cell cycle (Georgetown, Tex.) 2012;11(14):2756-61.
2012: Federica Sotgia; Diana Whitaker-Menezes; Agnieszka Witkiewicz; Ubaldo E Martinez-Outschoorn; Richard G Pestell; Nancy J Philp; Ruth C Birbe; Neal Flomenberg; Anthony Howell; Michael P Lisanti
Mitochondrial metabolism in cancer metastasis: visualizing tumor cell mitochondria and the "reverse Warburg effect" in positive lymph node tissue.
Cell cycle (Georgetown, Tex.) 2012;11(7):1445-54.
2012: Agnieszka Witkiewicz; Abhijit Dasgupta; Ricardo Gandara; Zhao Lin; Ubaldo E Martinez-Outschoorn; Nancy J Philp; Sharon Sneddon; Federica Sotgia; Diana Whitaker-Menezes; Michael P Lisanti
Using the "reverse Warburg effect" to identify high-risk breast cancer patients: stromal MCT4 predicts poor clinical outcome in triple-negative breast cancers.
Cell cycle (Georgetown, Tex.) 2012;11(6):1108-17.
2012: Amit Mahipal; Mary J Mcdonald; Agnieszka Witkiewicz; Brian I Carr
Cell membrane and cytoplasmic epidermal growth factor receptor expression in pancreatic ductal adenocarcinoma.
Medical oncology (Northwood, London, England) 2012;29(1):134-9.
2012: Matias E Valsecchi; Charles J Yeo; Jonathan R Brody; Thomas Holdbrook; Benjamin E Leiby; Susan J Littman; Ed Pequignot; Agnieszka Witkiewicz
Is there a role for the quantification of RRM1 and ERCC1 expression in pancreatic ductal adenocarcinoma?
BMC cancer 2012;12():104.
2011: Barbara Chiavarina; Rene Daniel; Anthony Howell; Ubaldo E Martinez-Outschoorn; Richard G Pestell; Johanna Smith; Federica Sotgia; Diana Whitaker-Menezes; Agnieszka Witkiewicz; Ruth Birbe; Michael P Lisanti
Pyruvate kinase expression (PKM1 and PKM2) in cancer-associated fibroblasts drives stromal nutrient production and tumor growth.
Cancer biology & therapy 2011;12(12):1101-13.
2011: Karen N Wu; Jonathan R Brody; Michael P Lisanti; Magdalena B Potoczek; Maria Queenan; Federica Sotgia; Agnieszka Witkiewicz
Loss of stromal caveolin-1 expression in malignant melanoma metastases predicts poor survival.
Cell cycle (Georgetown, Tex.) 2011;10(24):4250-5.
2011: David W Rittenhouse; Vanessa A Talbott; Agnieszka Witkiewicz; Zafia Anklesaria; Jonathan R Brody; Charles J Yeo
Subject review: pancreatic ductal adenocarcinoma in the setting of mutations in the cystic fibrosis transmembrane conductance regulator gene: case report and review of the literature.
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2011;15(12):2284-90.
2011: A Kathleen McClendon; Christopher A Reed; Dayana B Rivadeneira; Agnieszka Witkiewicz; Christopher N Mayhew; Sankar Addya; Ryan J Bourgo; Jeffry L Dean; Adam Ertel; Paolo Fortina; Zhiyan Fu; H Leighton Grimes; Erik S Knudsen
RB and p53 cooperate to prevent liver tumorigenesis in response to tissue damage.
Gastroenterology 2011;141(4):1439-50.
2011: Agnieszka Witkiewicz; Dayana B Rivadeneira; Gordon F Schwartz; Adam Ertel; Paolo Fortina; Terry Hyslop; Jessica Kline; Erik S Knudsen
Association of RB/p16-pathway perturbations with DCIS recurrence: dependence on tumor versus tissue microenvironment.
The American journal of pathology 2011;179(3):1171-8.
2011: Ryan J Bourgo; Adam Ertel; Jacqueline Bergseid; A Kathleen McClendon; Chellappagounder Thangavel; Jean Y J Wang; Ludwig Wilkens; Agnieszka Witkiewicz; Erik S Knudsen
RB restricts DNA damage-initiated tumorigenesis through an LXCXE-dependent mechanism of transcriptional control.
Molecular cell 2011;43(4):663-72.
2011: Agnieszka Witkiewicz; Karen E Knudsen; Adam P Dicker; Erik S Knudsen
The meaning of p16(ink4a) expression in tumors: functional significance, clinical associations and future developments.
Cell cycle (Georgetown, Tex.) 2011;10(15):2497-503.
2011: Cecilia J de Almeida; Philippe G Frank; Jean-François Jasmin; Federica Sotgia; Herbert B Tanowitz; Agnieszka Witkiewicz; Michael P Lisanti
Caveolin-2-deficient mice show increased sensitivity to endotoxemia.
Cell cycle (Georgetown, Tex.) 2011;10(13):2151-61.
2011: Amy R Peck; Ed Pequignot; David L Rimm; Anne L Rosenberg; Guido Sauter; Craig D Shriver; Ginger A Stringer; Thai H Tran; Agnieszka Witkiewicz; Ning Yang; Boris Freydin; Jeffrey A Hooke; Terry Hyslop; Alexander C Klimowicz; Albert J Kovatich; Chengbao Liu; anthony magliocco; Marja T Nevalainen; Hallgeir Rui
Loss of nuclear localized and tyrosine phosphorylated Stat5 in breast cancer predicts poor clinical outcome and increased risk of antiestrogen therapy failure.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2011;29(18):2448-58.
2011: Remedios Castello-Cros; Anthony Howell; Ruth C Birbe; Franco Capozza; Alex Molchansky; Richard G Pestell; Federica Sotgia; Diana Whitaker-Menezes; Agnieszka Witkiewicz; Gloria Bonuccelli; Michael P Lisanti
Matrix remodeling stimulates stromal autophagy, "fueling" cancer cell mitochondrial metabolism and metastasis.
Cell cycle (Georgetown, Tex.) 2011;10(12):2021-34.
2011: Diana Whitaker-Menezes; Agnieszka Witkiewicz; Ruth C Birbe; Adam Ertel; Neal Flomenberg; Ricardo Gandara; Anthony Howell; Zhao Lin; Ubaldo E Martinez-Outschoorn; Stephanos Pavlides; Richard G Pestell; Nancy J Philp; Federica Sotgia; Michael P Lisanti
Evidence for a stromal-epithelial "lactate shuttle" in human tumors: MCT4 is a marker of oxidative stress in cancer-associated fibroblasts.
Cell cycle (Georgetown, Tex.) 2011;10(11):1772-83.
2011: Agnieszka Witkiewicz; Erhan Bilal; Jonathan R Brody; Adam Ertel; Jessica Kline; Stephanos Pavlides; Maria Queenan; Federica Sotgia; Aristotelis Tsirigos; Michael P Lisanti
Molecular profiling of a lethal tumor microenvironment, as defined by stromal caveolin-1 status in breast cancers.
Cell cycle (Georgetown, Tex.) 2011;10(11):1794-809.
2011: Agnieszka Witkiewicz; Erik S Knudsen
RB pathway and therapeutic sensitivity: new insights in breast cancer and Tamoxifen therapy.
Cell cycle (Georgetown, Tex.) 2011;10(10):1525.
2010: Gemma Llaverias; Christiane Danilo; Yu Wang; Agnieszka Witkiewicz; Kristin Daumer; Michael P Lisanti; Philippe G Frank
A Western-type diet accelerates tumor progression in an autochthonous mouse model of prostate cancer.
The American journal of pathology 2010;177(6):3180-91.
2010: Kevin J Johnson; Amy R Peck; Chengbao Liu; Thai H Tran; Fransiscus Utama; Ashley B Sjolund; John D Schaber; Agnieszka Witkiewicz; Hallgeir Rui
PTP1B suppresses prolactin activation of Stat5 in breast cancer cells.
The American journal of pathology 2010;177(6):2971-83.
2010: Adam Ertel; Jeffry L Dean; Hallgeir Rui; Chengbao Liu; Agnieszka Witkiewicz; Karen E Knudsen; Erik S Knudsen
RB-pathway disruption in breast cancer: differential association with disease subtypes, disease-specific prognosis and therapeutic response.
Cell cycle (Georgetown, Tex.) 2010;9(20):4153-63.
2010: Melissa Lazar; Jennifer Sullivan; Galina Chipitsyna; Qiaoke Gong; Chee Y Ng; Ahmed Salem; Tamer Aziz; Agnieszka Witkiewicz; David T Denhardt; Charles J Yeo; Hwyda A Arafat
Involvement of osteopontin in the matrix-degrading and proangiogenic changes mediated by nicotine in pancreatic cancer cells.
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2010;14(10):1566-77.
2010: Michael P Lisanti; Ubaldo E Martinez-Outschoorn; Barbara Chiavarina; Stephanos Pavlides; Diana Whitaker-Menezes; Aristotelis Tsirigos; Agnieszka Witkiewicz; Zhao Lin; Renee Balliet; Anthony Howell; Federica Sotgia
Understanding the "lethal" drivers of tumor-stroma co-evolution: emerging role(s) for hypoxia, oxidative stress and autophagy/mitophagy in the tumor micro-environment.
Cancer biology & therapy 2010;10(6):537-42.
2010: Jonathan R Brody; Agnieszka Witkiewicz
CXCR4 signaling identifies a role for IFT2 in ER-negative breast cancers.
Cancer biology & therapy 2010;10(6):615-6.
2010: Ubaldo E Martinez-Outschoorn; Casey Trimmer; Zhao Lin; Diana Whitaker-Menezes; Barbara Chiavarina; Jie Zhou; Chengwang Wang; Stephanos Pavlides; Maria P Martinez-Cantarin; Franco Capozza; Agnieszka Witkiewicz; Neal Flomenberg; Anthony Howell; Richard G Pestell; Jaime Caro; Michael P Lisanti; Federica Sotgia
Autophagy in cancer associated fibroblasts promotes tumor cell survival: Role of hypoxia, HIF1 induction and NFκB activation in the tumor stromal microenvironment.
Cell cycle (Georgetown, Tex.) 2010;9(17):3515-33.
2010: Nathan G Richards; David W Rittenhouse; Boris Freydin; Joseph A Cozzitorto; Dane Grenda; Hallgeir Rui; Greg Gonye; Eugene P Kennedy; Charles J Yeo; Jonathan R Brody; Agnieszka Witkiewicz
HuR status is a powerful marker for prognosis and response to gemcitabine-based chemotherapy for resected pancreatic ductal adenocarcinoma patients.
Annals of surgery 2010;252(3):499-505; discussion 505-6.
2010: daniel brown; Carin F Gonsalves; Charles J Yeo; Agnieszka Witkiewicz; Brian I Carr
One year survival with poorly differentiated metastatic pancreatic carcinoma following chemoembolization with gemcitabine and cisplatin.
Oncology reports 2010;24(3):767-9.
2010: Adam D Toll; Abhijit Dasgupta; Magdalena Potoczek; Charles J Yeo; Celina G Kleer; Jonathan R Brody; Agnieszka Witkiewicz
Implications of enhancer of zeste homologue 2 expression in pancreatic ductal adenocarcinoma.
Human pathology 2010;41(9):1205-9.
2010: Ubaldo E Martinez-Outschoorn; Renee M Balliet; Dayana B Rivadeneira; Barbara Chiavarina; Stephanos Pavlides; Chenguang Wang; Diana Whitaker-Menezes; Kristin M Daumer; Zhao Lin; Agnieszka Witkiewicz; Neal Flomenberg; Anthony Howell; Richard G Pestell; Erik S Knudsen; Federica Sotgia; Michael P Lisanti
Oxidative stress in cancer associated fibroblasts drives tumor-stroma co-evolution: A new paradigm for understanding tumor metabolism, the field effect and genomic instability in cancer cells.
Cell cycle (Georgetown, Tex.) 2010;9(16):3256-76.
2010: Agnieszka Witkiewicz; Boris Freydin; Inna Chervoneva; Magdalena B Potoczek; Wendy Rizzo; Hallgeir Rui; Jonathan R Brody; Gordon Schwartz; Michael P Lisanti
Stromal CD10 and SPARC expression in ductal carcinoma in situ (DCIS) patients predicts disease recurrence.
Cancer biology & therapy 2010;10(4):391-6.
2010: Melissa Lazar; Jennifer Sullivan; Galina Chipitsyna; Tamer Aziz; Ahmed Salem; Qiaoke Gong; Agnieszka Witkiewicz; David T Denhardt; Charles J Yeo; Hwyda A Arafat
Induction of monocyte chemoattractant protein-1 by nicotine in pancreatic ductal adenocarcinoma cells: role of osteopontin.
Surgery 2010;148(2):298-309.
2010: Agnieszka Witkiewicz; Abhijit Dasgupta; Sara Sammons; Ozlem Er; Magdalena B Potoczek; Fran Guiles; Federica Sotgia; Jonathan R Brody; Edith P Mitchell; Michael P Lisanti
Loss of stromal caveolin-1 expression predicts poor clinical outcome in triple negative and basal-like breast cancers.
Cancer biology & therapy 2010;10(2):135-43.
2010: Ubaldo E Martinez-Outschoorn; Stephanos Pavlides; Diana Whitaker-Menezes; Kristin M Daumer; Janet N Milliman; Barbara Chiavarina; Gemma Migneco; Agnieszka Witkiewicz; Maria P Martinez-Cantarin; Neal Flomenberg; Anthony Howell; Richard G Pestell; Michael P Lisanti; Federica Sotgia
Tumor cells induce the cancer associated fibroblast phenotype via caveolin-1 degradation: implications for breast cancer and DCIS therapy with autophagy inhibitors.
Cell cycle (Georgetown, Tex.) 2010;9(12):2423-33.
2010: Daniel Relles; Jennie Baek; Agnieszka Witkiewicz; Charles J Yeo
Periampullary and duodenal neoplasms in neurofibromatosis type 1: two cases and an updated 20-year review of the literature yielding 76 cases.
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2010;14(6):1052-61.
2010: Gloria Bonuccelli; Diana Whitaker-Menezes; Remedios Castello-Cros; Stephanos Pavlides; Richard G Pestell; Alessandro Fatatis; Agnieszka Witkiewicz; Matthew G Vander Heiden; Gemma Migneco; Barbara Chiavarina; Philippe G Frank; Franco Capozza; Neal Flomenberg; Ubaldo E Martinez-Outschoorn; Federica Sotgia; Michael P Lisanti
The reverse Warburg effect: glycolysis inhibitors prevent the tumor promoting effects of caveolin-1 deficient cancer associated fibroblasts.
Cell cycle (Georgetown, Tex.) 2010;9(10):1960-71.
2010: Shayna L Showalter; Ziqiu Wang; Christina L Costantino; Agnieszka Witkiewicz; Charles J Yeo; Jonathan R Brody; Brian I Carr
Naturally occurring K vitamins inhibit pancreatic cancer cell survival through a caspase-dependent pathway.
Journal of gastroenterology and hepatology 2010;25(4):738-44.
2010: Shayna L Showalter; Sarah Charles; Justin Belin; Joseph Cozzitorto; Peter Einstein; Nathan G Richards; Patricia K Sauter; Eugene P Kennedy; Agnieszka Witkiewicz; Jonathan R Brody; Charles J Yeo
Identifying pancreatic cancer patients for targeted treatment: the challenges and limitations of the current selection process and vision for the future.
Expert opinion on drug delivery 2010;7(3):273-84.
2010: Thai H Tran; Fransiscus Utama; Justin Lin; Ning Yang; Ashley B Sjolund; Amy Ryder; Kevin J Johnson; Lynn M Neilson; Chengbao Liu; Kristin L Brill; Anne L Rosenberg; Agnieszka Witkiewicz; Hallgeir Rui
Prolactin inhibits BCL6 expression in breast cancer through a Stat5a-dependent mechanism.
Cancer research 2010;70(4):1711-21.
2010: Timothy K Williams; Christina L Costantino; Nikolai A Bildzukewicz; Nathan G Richards; David W Rittenhouse; Lisa Einstein; Joseph A Cozzitorto; Judith C Keen; Abhijit Dasgupta; Myriam Gorospe; Gregory E Gonye; Charles J Yeo; Agnieszka Witkiewicz; Jonathan R Brody
pp32 (ANP32A) expression inhibits pancreatic cancer cell growth and induces gemcitabine resistance by disrupting HuR binding to mRNAs.
PloS one 2010;5(11):e15455.
2010: Agnieszka Witkiewicz; THOMAS MCCONNELL; Magdalena Potoczek; Robert V B Emmons; Robert J Kurman
Increased natural killer cells and decreased regulatory T cells are seen in complex atypical endometrial hyperplasia and well-differentiated carcinoma treated with progestins.
Human pathology 2010;41(1):26-32.
2009: Stephanos Pavlides; Diana Whitaker-Menezes; Remedios Castello-Cros; Neal Flomenberg; Agnieszka Witkiewicz; Philippe G Frank; Mathew C Casimiro; Chenguang Wang; Paolo Fortina; Sankar Addya; Richard G Pestell; Ubaldo E Martinez-Outschoorn; Federica Sotgia; Michael P Lisanti
The reverse Warburg effect: aerobic glycolysis in cancer associated fibroblasts and the tumor stroma.
Cell cycle (Georgetown, Tex.) 2009;8(23):3984-4001.
2009: Karen N Wu; Robert V B Emmons; Michael P Lisanti; John L Farber; Agnieszka Witkiewicz
Foxp3-expressing T regulatory cells and mast cells in acute graft-versus-host disease of the skin.
Cell cycle (Georgetown, Tex.) 2009;8(21):3593-7.
2009: Harish Lavu; Andres A Mascaro; Dane R Grenda; Patricia K Sauter; Benjamin E Leiby; Sean P Croker; Agnieszka Witkiewicz; Adam C Berger; Ernest L Rosato; Eugene P Kennedy; Charles J Yeo
Margin positive pancreaticoduodenectomy is superior to palliative bypass in locally advanced pancreatic ductal adenocarcinoma.
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2009;13(11):1937-46; discussion 1946-7.
2009: Jennifer Sullivan; Laurel Blair; Amer Alnajar; Tamer Aziz; Chee Yuan Ng; Galina Chipitsyna; Qiaoke Gong; Agnieszka Witkiewicz; Georg F Weber; David T Denhardt; Charles J Yeo; Hwyda A Arafat
Expression of a prometastatic splice variant of osteopontin, OPNC, in human pancreatic ductal adenocarcinoma.
Surgery 2009;146(2):232-40.
2009: Jonathan R Brody; Christina L Costantino; Adam C Berger; Takami Sato; Michael P Lisanti; Charles J Yeo; Robert V Emmons; Agnieszka Witkiewicz
Expression of indoleamine 2,3-dioxygenase in metastatic malignant melanoma recruits regulatory T cells to avoid immune detection and affects survival.
Cell cycle (Georgetown, Tex.) 2009;8(12):1930-4.
2009: Agnieszka Witkiewicz; Abhijit Dasgupta; Katherine H Nguyen; Chengbao Liu; Albert J Kovatich; Gordon Schwartz; Richard G Pestell; Federica Sotgia; Hallgeir Rui; Michael P Lisanti
Stromal caveolin-1 levels predict early DCIS progression to invasive breast cancer.
Cancer biology & therapy 2009;8(11):1071-9.
2009: Christina L Costantino; Agnieszka Witkiewicz; Yuki Kuwano; Joseph A Cozzitorto; Eugene P Kennedy; Abhijit Dasgupta; Judith C Keen; Charles J Yeo; Myriam Gorospe; Jonathan R Brody
The role of HuR in gemcitabine efficacy in pancreatic cancer: HuR Up-regulates the expression of the gemcitabine metabolizing enzyme deoxycytidine kinase.
Cancer research 2009;69(11):4567-72.
2009: Agnieszka Witkiewicz; Mathew C Casimiro; Abhijit Dasgupta; Isabelle Mercier; Chenguang Wang; Gloria Bonuccelli; Jean-François Jasmin; Philippe G Frank; Richard G Pestell; Celina G Kleer; Federica Sotgia; Michael P Lisanti
Towards a new "stromal-based" classification system for human breast cancer prognosis and therapy.
Cell cycle (Georgetown, Tex.) 2009;8(11):1654-8.
2009: Agnieszka Witkiewicz; Abhijit Dasgupta; Federica Sotgia; Isabelle Mercier; Richard G Pestell; Michael Sabel; Celina G Kleer; Jonathan R Brody; Michael P Lisanti
An absence of stromal caveolin-1 expression predicts early tumor recurrence and poor clinical outcome in human breast cancers.
The American journal of pathology 2009;174(6):2023-34.
2009: Agnieszka Witkiewicz; Christina L Costantino; Richard Metz; Alexander J Muller; George C Prendergast; Charles J Yeo; Jonathan R Brody
Genotyping and expression analysis of IDO2 in human pancreatic cancer: a novel, active target.
Journal of the American College of Surgeons 2009;208(5):781-7; discussion 787-9.
2009: Isabelle Mercier; Kelly G Bryant; Federica Sotgia; Gloria Bonuccelli; Agnieszka Witkiewicz; Abhijit Dasgupta; Jean-François Jasmin; Richard G Pestell; Michael P Lisanti
Using Caveolin-1 epithelial immunostaining patterns to stratify human breast cancer patients and predict the Caveolin-1 (P132L) mutation.
Cell cycle (Georgetown, Tex.) 2009;8(9):1396-401.
2009: Jonathan R Brody; Christina L Costantino; Magdalena Potoczek; Joseph Cozzitorto; Peter McCue; Charles J Yeo; Ralph Hruban; Agnieszka Witkiewicz
Adenosquamous carcinoma of the pancreas harbors KRAS2, DPC4 and TP53 molecular alterations similar to pancreatic ductal adenocarcinoma.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2009;22(5):651-9.
2009: Isabelle Mercier; Mathew C Casimiro; Jie Zhou; Chenguang Wang; Christopher Plymire; Kelly G Bryant; Kristin M Daumer; Federica Sotgia; Gloria Bonuccelli; Agnieszka Witkiewicz; Justin Lin; Thai Hong Tran; Janet Milliman; Philippe G Frank; Jean-François Jasmin; Hallgeir Rui; Richard G Pestell; Michael P Lisanti
Genetic ablation of caveolin-1 drives estrogen-hypersensitivity and the development of DCIS-like mammary lesions.
The American journal of pathology 2009;174(4):1172-90.
2009: Federica Sotgia; francesco del galdo; Mathew C Casimiro; Gloria Bonuccelli; Isabelle Mercier; Diana Whitaker-Menezes; Kristin M Daumer; Jie Zhou; Chenguang Wang; Sanjay Katiyar; Huan Xu; Emily Bosco; Andrew A Quong; Bruce Aronow; Agnieszka Witkiewicz; Carlo Minetti; Philippe G Frank; Sergio A Jimenez; Erik S Knudsen; Richard G Pestell; Michael P Lisanti
Caveolin-1-/- null mammary stromal fibroblasts share characteristics with human breast cancer-associated fibroblasts.
The American journal of pathology 2009;174(3):746-61.
2008: Shayna L Showalter; Yu-Hung Huang; Agnieszka Witkiewicz; Christina L Costantino; Charles J Yeo; Jordan Green; Robert Langer; Daniel G Anderson; Janet A Sawicki; Jonathan R Brody
Nanoparticulate delivery of diphtheria toxin DNA effectively kills Mesothelin expressing pancreatic cancer cells.
Cancer biology & therapy 2008;7(10):1584-90.
2008: Agnieszka Witkiewicz; Katherine H Nguyen; Abhijit Dasgupta; Eugene P Kennedy; Charles J Yeo; Michael P Lisanti; Jonathan R Brody
Co-expression of fatty acid synthase and caveolin-1 in pancreatic ductal adenocarcinoma: implications for tumor progression and clinical outcome.
Cell cycle (Georgetown, Tex.) 2008;7(19):3021-5.
2008: Agnieszka Witkiewicz; Eugene P Kennedy; Lawrence Kennyon; Charles J Yeo; Ralph Hruban
Synchronous autoimmune pancreatitis and infiltrating pancreatic ductal adenocarcinoma: case report and review of the literature.
Human pathology 2008;39(10):1548-51.
2008: Christine Hostetter; Lauren A Licata; Agnieszka Witkiewicz; Christina L Costantino; Charles J Yeo; Jonathan R Brody; Judith Clancy Keen
Cytoplasmic accumulation of the RNA binding protein HuR is central to tamoxifen resistance in estrogen receptor positive breast cancer cells.
Cancer biology & therapy 2008;7(9):1496-506.
2008: Monika Kasprzycka; Qian Zhang; Agnieszka Witkiewicz; Michal Marzec; Magdalena Potoczek; Xiaobin Liu; Hong Yi Wang; Michael Milone; Samik Basu; Joanne Mauger; John K Choi; JT Abrams; J Steven Hou; Alain H Rook; Eric Vonderheid; Anders Woetmann; Niels Odum; Mariusz A Wasik
Gamma c-signaling cytokines induce a regulatory T cell phenotype in malignant CD4+ T lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(4):2506-12.
2008: Isabelle Mercier; Mathew C Casimiro; Chenguang Wang; Anne L Rosenberg; Judy Quong; Alimatou Minkeu; Kathleen G Allen; Christiane Danilo; Federica Sotgia; Gloria Bonuccelli; Jean-François Jasmin; Huan Xu; Emily Bosco; Bruce Aronow; Agnieszka Witkiewicz; Richard G Pestell; Erik S Knudsen; Michael P Lisanti
Human breast cancer-associated fibroblasts (CAFs) show caveolin-1 downregulation and RB tumor suppressor functional inactivation: Implications for the response to hormonal therapy.
Cancer biology & therapy 2008;7(8):1212-25.
2008: Elias E Ayli; Weijie Li; Tamu T Brown; Agnieszka Witkiewicz; Rosalie Elenitsas; John T Seykora
Activation of Src-family tyrosine kinases in hyperproliferative epidermal disorders.
Journal of cutaneous pathology 2008;35(3):273-7.
2008: Michal Marzec; Xiaobin Liu; Monika Kasprzycka; Agnieszka Witkiewicz; Puthiyaveettil N Raghunath; Mouna El-Salem; Erle Robertson; Niels Odum; Mariusz A Wasik
IL-2- and IL-15-induced activation of the rapamycin-sensitive mTORC1 pathway in malignant CD4+ T lymphocytes.
Blood 2008;111(4):2181-9.
2006: Julie V Schaffer; Hisham Bazzi; Anna Vitebsky; Agnieszka Witkiewicz; Olympia I Kovich; Hideko Kamino; Lawrence S Shapiro; Snehal P Amin; Seth J Orlow; Angela M Christiano
Mutations in the desmoglein 4 gene underlie localized autosomal recessive hypotrichosis with monilethrix hairs and congenital scalp erosions.
The Journal of investigative dermatology 2006;126(6):1286-91.
2006: Julie V Schaffer; Hideko Kamino; Agnieszka Witkiewicz; Jennifer M McNiff; Seth J Orlow
Mucocutaneous neuromas: an underrecognized manifestation of PTEN hamartoma-tumor syndrome.
Archives of dermatology 2006;142(5):625-32.
2005: Agnieszka Witkiewicz; Kenneth R Lee; Gilbert Brodsky; Aida Cviko; Joshua Brodsky; Christopher P Crum
Superficial (early) endocervical adenocarcinoma in situ: a study of 12 cases and comparison to conventional AIS.
The American journal of surgical pathology 2005;29(12):1609-14.
2005: Agnieszka Witkiewicz; Sooryanarayana Lnu; Ronglai Shen; Rohit Mehra; Michael Sabel; Debashis Ghosh; Arul M Chinnaiyan; Mark A Rubin; Celina G Kleer
Alpha-methylacyl-CoA racemase protein expression is associated with the degree of differentiation in breast cancer using quantitative image analysis.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2005;14(6):1418-23.
2005: Jorge Albores-Saavedra; Steven Cooper Heard; Bernadette K McLaren; Hideko Kamino; Agnieszka Witkiewicz
Cylindroma (dermal analog tumor) of the breast: a comparison with cylindroma of the skin and adenoid cystic carcinoma of the breast.
American journal of clinical pathology 2005;123(6):866-73.
2005: Agnieszka Witkiewicz; Jonathan L Hecht; Aida Cviko; Frank D McKeon; Tan Ince; Christopher P Crum
Microglandular hyperplasia: a model for the de novo emergence and evolution of endocervical reserve cells.
Human pathology 2005;36(2):154-61.
2005: Jennifer Bragg; Agnieszka Witkiewicz; Seth J Orlow; Julie V Schaffer
Pityriasis rubra pilaris, type IV.
Dermatology online journal 2005;11(4):14.
2005: J Scott Henning; Agnieszka Witkiewicz; Julie V Schaffer; Seth J Orlow
Juvenile amyopathic dermatomyositis.
Dermatology online journal 2005;11(4):11.