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David Witte

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Jaya K George-Abraham; Robert B Hinton; Bradley S Marino; David P Witte; Sarah L Zimmerman; Robert J Hopkin
Tetrasomy 15q25.2→qter identified with SNP microarray in a patient with multiple anomalies including complex cardiovascular malformation.
Nadine M Brown; Stephanie L Lindley; David P Witte; Kenneth D R Setchell
Impact of perinatal exposure to equol enantiomers on reproductive development in rodents.
Pirooz Eghtesady; Erik C Michelfelder; Timothy K Knilans; David P Witte; Peter B Manning; Timothy M Crombleholme
Fetal surgical management of congenital heart block in a hydropic fetus: lessons learned from a clinical experience.

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All Publications

2012: Jaya K George-Abraham; Robert B Hinton; Bradley S Marino; David P Witte; Sarah L Zimmerman; Robert J Hopkin
Tetrasomy 15q25.2→qter identified with SNP microarray in a patient with multiple anomalies including complex cardiovascular malformation.
American journal of medical genetics. Part A 2012;158A(8):1971-6.
2011: Nadine M Brown; Stephanie L Lindley; David P Witte; Kenneth D R Setchell
Impact of perinatal exposure to equol enantiomers on reproductive development in rodents.
Reproductive toxicology (Elmsford, N.Y.) 2011;32(1):33-42.
2011: Pirooz Eghtesady; Erik C Michelfelder; Timothy K Knilans; David P Witte; Peter B Manning; Timothy M Crombleholme
Fetal surgical management of congenital heart block in a hydropic fetus: lessons learned from a clinical experience.
The Journal of thoracic and cardiovascular surgery 2011;141(3):835-7.
2010: Nadine M Brown; C A Belles; S L Lindley; L Zimmer-Nechemias; David P Witte; Mi-Ok Kim; K D R Setchell
Mammary gland differentiation by early life exposure to enantiomers of the soy isoflavone metabolite equol.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2010;48(11):3042-50.
2010: Nadine M Brown; Carrie A Belles; Stephanie L Lindley; Linda D Zimmer-Nechemias; Xueheng Zhao; David P Witte; Mi-Ok Kim; Kenneth D R Setchell
The chemopreventive action of equol enantiomers in a chemically induced animal model of breast cancer.
Carcinogenesis 2010;31(5):886-93.
2010: Kris A Steinbrecher; Netanel A Horowitz; Elizabeth A Blevins; Kelley A Barney; Maureen A Shaw; Eleana Harmel-Laws; Fred D Finkelman; Matthew J Flick; Malinda D Pinkerton; Kathryn E Talmage; Keith W Kombrinck; David P Witte; Joseph S Palumbo
Colitis-associated cancer is dependent on the interplay between the hemostatic and inflammatory systems and supported by integrin alpha(M)beta(2) engagement of fibrinogen.
Cancer research 2010;70(7):2634-43.
2010: Ying Sun; Huimin Ran; Matt Zamzow; Kazuyuki Kitatani; Matthew R Skelton; Michael T Williams; Charles V Vorhees; David P Witte; Yusuf A Hannun; Gregory A Grabowski
Specific saposin C deficiency: CNS impairment and acid beta-glucosidase effects in the mouse.
Human molecular genetics 2010;19(4):634-47.
2009: Jenifer R Prosperi; Kimberly R Becher; Tara A Willson; Margaret H Collins; David P Witte; Kathleen Heppner Goss
The APC tumor suppressor is required for epithelial integrity in the mouse mammary gland.
Journal of cellular physiology 2009;220(2):319-31.
2009: Eric S Mullins; Keith W Kombrinck; Kathryn E Talmage; Maureen A Shaw; David P Witte; Joni M Ullman; Sandra J F Degen; William Sun; Matthew J Flick; Jay L Degen
Genetic elimination of prothrombin in adult mice is not compatible with survival and results in spontaneous hemorrhagic events in both heart and brain.
Blood 2009;113(3):696-704.
2008: Ying Sun; David P Witte; Huimin Ran; Matt Zamzow; Sonya Barnes; hua cheng; Xianlin Han; Michael T Williams; Matthew R Skelton; Charles V Vorhees; Gregory A Grabowski
Neurological deficits and glycosphingolipid accumulation in saposin B deficient mice.
Human molecular genetics 2008;17(15):2345-56.
2008: Ying Sun; Li Jia; Michael T Williams; Matt Zamzow; Huimin Ran; Brian Quinn; Bruce Aronow; Charles V Vorhees; David P Witte; Gregory A Grabowski
Temporal gene expression profiling reveals CEBPD as a candidate regulator of brain disease in prosaposin deficient mice.
BMC neuroscience 2008;9():76.
2007: Matthew J Flick; Christine M LaJeunesse; Kathryn E Talmage; David P Witte; Joseph S Palumbo; Malinda D Pinkerton; Sherry Thornton; Jay L Degen
Fibrin(ogen) exacerbates inflammatory joint disease through a mechanism linked to the integrin alphaMbeta2 binding motif.
The Journal of clinical investigation 2007;117(11):3224-35.
2007: Ying Sun; David P Witte; Matt Zamzow; Huimin Ran; Brian Quinn; Junko Matsuda; Gregory A Grabowski
Combined saposin C and D deficiencies in mice lead to a neuronopathic phenotype, glucosylceramide and alpha-hydroxy ceramide accumulation, and altered prosaposin trafficking.
Human molecular genetics 2007;16(8):957-71.
2007: Michael R Bennett; Kimberly Ann Czech; Lois J Arend; David P Witte; Prasad Devarajan; steven potter
Laser capture microdissection-microarray analysis of focal segmental glomerulosclerosis glomeruli.
Nephron. Experimental nephrology 2007;107(1):e30-40.
2006: Ying Sun; Brian Quinn; You-Hai Xu; Tatyana Leonova; David P Witte; Gregory A Grabowski
Conditional expression of human acid beta-glucosidase improves the visceral phenotype in a Gaucher disease mouse model.
Journal of lipid research 2006;47(10):2161-70.
2005: Ying Sun; Brian Quinn; David P Witte; Gregory A Grabowski
Gaucher disease mouse models: point mutations at the acid beta-glucosidase locus combined with low-level prosaposin expression lead to disease variants.
Journal of lipid research 2005;46(10):2102-13.
2005: Elizabeth A Mann; Kris A Steinbrecher; Carmen Stroup; David P Witte; Mitchell B Cohen; Ralph A Giannella
Lack of guanylyl cyclase C, the receptor for Escherichia coli heat-stable enterotoxin, results in reduced polyp formation and increased apoptosis in the multiple intestinal neoplasia (Min) mouse model.
International journal of cancer. Journal international du cancer 2005;116(4):500-5.
2005: Stavra A Xanthakos; Jeffrey B Schwimmer; Hector Melin-Aldana; Marc E Rothenberg; David P Witte; Mitchell B Cohen
Prevalence and outcome of allergic colitis in healthy infants with rectal bleeding: a prospective cohort study.
Journal of pediatric gastroenterology and nutrition 2005;41(1):16-22.
2005: Nives Zimmermann; Matthew P Doepker; David P Witte; Keith F Stringer; Patricia C Fulkerson; Samuel M Pope; Eric B Brandt; Anil Mishra; Nina E King; Nikolaos M Nikolaidis; MARSHA WILLS-KARP; Fred D Finkelman; Marc E Rothenberg
Expression and regulation of small proline-rich protein 2 in allergic inflammation.
American journal of respiratory cell and molecular biology 2005;32(5):428-35.
2005: L M Hermann; M Pinkerton; K Jennings; L Yang; Alexei A Grom; Dawn Sowders; S Kersten; David P Witte; Raphael Hirsch; Sherry Thornton
Angiopoietin-like-4 is a potential angiogenic mediator in arthritis.
Clinical immunology (Orlando, Fla.) 2005;115(1):93-101.
2005: Zhengtao Chu; David P Witte; Xiaoyang Qi
Saposin C-LBPA interaction in late-endosomes/lysosomes.
Experimental cell research 2005;303(2):300-7.
2004: Samuel C Blackman; Nell S Lurain; David P Witte; Alexandra H Filipovich; Pam Groen; Mark R Schleiss
Emergence and compartmentalization of fatal multi-drug-resistant cytomegalovirus infection in a patient with autosomal-recessive severe combined immune deficiency.
Journal of pediatric hematology/oncology 2004;26(9):601-5.
2004: Nina E King; Nives Zimmermann; Samuel M Pope; Patricia C Fulkerson; Nikolaos M Nikolaidis; Anil Mishra; David P Witte; Marc E Rothenberg
Expression and regulation of a disintegrin and metalloproteinase (ADAM) 8 in experimental asthma.
American journal of respiratory cell and molecular biology 2004;31(3):257-65.
2004: Jianhua Zhang; Amy E Moseley; anil jegga; Ashima Gupta; David P Witte; Maureen Sartor; Mario Medvedovic; Sarah S Williams; Cathy Ley-Ebert; Lique M Coolen; Gregory Egnaczyk; Mary Beth Genter; Michael N Lehman; Jerry B Lingrel; John E Maggio; Linda Parysek; Ryan Walsh; Mingli Xu; Bruce Aronow
Neural system-enriched gene expression: relationship to biological pathways and neurological diseases.
Physiological genomics 2004;18(2):167-83.
2004: Kristopher Schwab; David P Witte; Bruce Aronow; Prasad Devarajan; steven potter; Larry T Patterson
Microarray analysis of focal segmental glomerulosclerosis.
American journal of nephrology 2004;24(4):438-47.
2004: Matthew J Flick; XinLi Du; David P Witte; Markéta Jirousková; Dmitry A Soloviev; Steven J Busuttil; Edward F Plow; Jay L Degen
Leukocyte engagement of fibrin(ogen) via the integrin receptor alphaMbeta2/Mac-1 is critical for host inflammatory response in vivo.
The Journal of clinical investigation 2004;113(11):1596-606.
2004: Deijanira Alves De Albuquerque; Vijay Saxena; David E Adams; Gregory P Boivin; Hermine I Brunner; David P Witte; Ram Raj Singh
An ACE inhibitor reduces Th2 cytokines and TGF-beta1 and TGF-beta2 isoforms in murine lupus nephritis.
Kidney international 2004;65(3):846-59.
2004: Patricia C Fulkerson; Nives Zimmermann; Eric B Brandt; Emily E Muntel; Matthew P Doepker; Jessica L Kavanaugh; Anil Mishra; David P Witte; Hongwei Zhang; Joshua M Farber; Ming Yang; Paul S Foster; Marc E Rothenberg
Negative regulation of eosinophil recruitment to the lung by the chemokine monokine induced by IFN-gamma (Mig, CXCL9).
Proceedings of the National Academy of Sciences of the United States of America 2004;101(7):1987-92.
2004: Hong Du; Susan Schiavi; Nick Wan; Mark Levine; David P Witte; Gregory A Grabowski
Reduction of atherosclerotic plaques by lysosomal acid lipase supplementation.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(1):147-54.
2003: Mary Beth Genter; Paul P Van Veldhoven; anil jegga; Bhuvaneswari Sakthivel; Sue Kong; Kristin Stanley; David P Witte; Catherine L Ebert; Bruce Aronow
Microarray-based discovery of highly expressed olfactory mucosal genes: potential roles in the various functions of the olfactory system.
Physiological genomics 2003;16(1):67-81.
2003: Joseph S Palumbo; Kathryn E Talmage; Hong Liu; Christine M La Jeunesse; David P Witte; Jay L Degen
Plasminogen supports tumor growth through a fibrinogen-dependent mechanism linked to vascular patency.
Blood 2003;102(8):2819-27.
2003: Nives Zimmermann; Nina E King; Johanne Laporte; Ming Yang; Anil Mishra; Samuel M Pope; Emily E Muntel; David P Witte; Anthony A Pegg; Paul S Foster; Qutayba Hamid; Marc E Rothenberg
Dissection of experimental asthma with DNA microarray analysis identifies arginase in asthma pathogenesis.
The Journal of clinical investigation 2003;111(12):1863-74.
2003: Ram Raj Singh; Vijay Saxena; Song Zang; Lily Li; Fred D Finkelman; David P Witte; Chaim O Jacob
Differential contribution of IL-4 and STAT6 vs STAT4 to the development of lupus nephritis.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(9):4818-25.
2003: C Frederic Strife; Clark D West; David P Witte
Crescentic glomerulonephritis in childhood: acute nonproliferative glomerulitis versus dense deposit disease.
American journal of kidney diseases : the official journal of the National Kidney Foundation 2003;41(4):897; author reply 898.
2003: Ying Sun; David P Witte; Peng Jin; Gregory A Grabowski
Analyses of temporal regulatory elements of the prosaposin gene in transgenic mice.
The Biochemical journal 2003;370(Pt 2):557-66.
2003: Amy E Moseley; Steve P Lieske; Randall K Wetzel; Paul F James; Suiwen He; Daniel Shelly; Richard J Paul; Gregory P Boivin; David P Witte; Jan-Marino Ramirez; Kathleen J Sweadner; Jerry B Lingrel
The Na,K-ATPase alpha 2 isoform is expressed in neurons, and its absence disrupts neuronal activity in newborn mice.
The Journal of biological chemistry 2003;278(7):5317-24.
2002: William Y Sun; Mallory J Coleman; David P Witte; Sandra J F Degen
Rescue of prothrombin-deficiency by transgene expression in mice.
Thrombosis and haemostasis 2002;88(6):984-91.
2002: Kris A Steinbrecher; Steve A Wowk; Jeffrey A Rudolph; David P Witte; Mitchell B Cohen
Targeted inactivation of the mouse guanylin gene results in altered dynamics of colonic epithelial proliferation.
The American journal of pathology 2002;161(6):2169-78.
2002: Sherry Thornton; Dawn Sowders; Bruce Aronow; David P Witte; Hermine I Brunner; Edward H Giannini; Raphael Hirsch
DNA microarray analysis reveals novel gene expression profiles in collagen-induced arthritis.
Clinical immunology (Orlando, Fla.) 2002;105(2):155-68.
2002: Rebecca C Brandy; Mark R Schleiss; David P Witte; Tariq A Siddiqi; Peter T Fame
Placental transfer of ganciclovir in a woman with acquired immunodeficiency syndrome and cytomegalovirus disease.
The Pediatric infectious disease journal 2002;21(8):796-7.
2002: Ying Sun; Xiaoyang Qi; David P Witte; Elvira Ponce; Keiji Kondoh; Brian Quinn; Gregory A Grabowski
Prosaposin: threshold rescue and analysis of the "neuritogenic" region in transgenic mice.
Molecular genetics and metabolism 2002;76(4):271-86.
2002: Hong Du; Martin Heur; David P Witte; Detlev Ameis; Gregory A Grabowski
Lysosomal acid lipase deficiency: correction of lipid storage by adenovirus-mediated gene transfer in mice.
Human gene therapy 2002;13(11):1361-72.
2002: David G Kuhel; Binghua Zhu; David P Witte; David Y Hui
Distinction in genetic determinants for injury-induced neointimal hyperplasia and diet-induced atherosclerosis in inbred mice.
Arteriosclerosis, thrombosis, and vascular biology 2002;22(6):955-60.
2002: Mark E Rosenberg; Richard Girton; David Finkel; David Chmielewski; Arthur Barrie; David P Witte; Guang Zhu; John J Bissler; Judith A K Harmony; Bruce Aronow
Apolipoprotein J/clusterin prevents a progressive glomerulopathy of aging.
Molecular and cellular biology 2002;22(6):1893-902.
2002: Michael T Valerius; Larry T Patterson; David P Witte; steven potter
Microarray analysis of novel cell lines representing two stages of metanephric mesenchyme differentiation.
Mechanisms of development 2002;112(1-2):219-32.
2002: Susan A McDowell; Ali Mallakin; Cindy J Bachurski; Kenya Toney-Earley; Daniel R Prows; Theresa Bruno; Klaus kaestner; David P Witte; Hector Melin-Aldana; Sandra J F Degen; George Leikauf; Susan E Waltz
The role of the receptor tyrosine kinase Ron in nickel-induced acute lung injury.
American journal of respiratory cell and molecular biology 2002;26(1):99-104.
2002: Michael T Valerius; Larry T Patterson; David P Witte; steven potter
Microarray analysis of novel cell lines representing two stages of metanephric mesenchyme differentiation.
Mechanisms of development 2002;110(1-2):151-64.
2001: Elvira Ponce; David P Witte; A Hung; Gregory A Grabowski
Temporal and spatial expression of murine acid beta-glucosidase mRNA.
Molecular genetics and metabolism 2001;74(4):426-34.
2001: TR Welch; M Frenzke; M C Carroll; David P Witte
Evidence of a role for C4 in modulating interstitial inflammation in experimental glomerulonephritis.
Clinical immunology (Orlando, Fla.) 2001;101(3):366-70.
2001: Angela F Drew; H L Tucker; H Liu; David P Witte; Jay L Degen; P G Tipping
Crescentic glomerulonephritis is diminished in fibrinogen-deficient mice.
American journal of physiology. Renal physiology 2001;281(6):F1157-63.
2001: Dennis W McGraw; N Fukuda; Paul F James; SL Forbes; Alison L Woo; Jerry B Lingrel; David P Witte; Michael A Matthay; Stephen B Liggett
Targeted transgenic expression of beta(2)-adrenergic receptors to type II cells increases alveolar fluid clearance.
American journal of physiology. Lung cellular and molecular physiology 2001;281(4):L895-903.
2001: Binghua Zhu; G Zhao; David P Witte; David Y Hui; James A Fagin
Targeted overexpression of IGF-I in smooth muscle cells of transgenic mice enhances neointimal formation through increased proliferation and cell migration after intraarterial injury.
Endocrinology 2001;142(8):3598-606.
2001: Eric W Brunskill; David P Witte; Katherine E Yutzey; steven potter
Novel cell lines promote the discovery of genes involved in early heart development.
Developmental biology 2001;235(2):507-20.
2001: Clark D West; David P Witte; AJ McAdams
Composition of nephritic factor-generated glomerular deposits in membranoproliferative glomerulonephritis type 2.
American journal of kidney diseases : the official journal of the National Kidney Foundation 2001;37(6):1120-30.
2001: Hong Du; Martin Heur; M Duanmu; Gregory A Grabowski; David Y Hui; David P Witte; J Mishra
Lysosomal acid lipase-deficient mice: depletion of white and brown fat, severe hepatosplenomegaly, and shortened life span.
Journal of lipid research 2001;42(4):489-500.
2000: Binghua Zhu; David G Kuhel; David P Witte; David Y Hui
Apolipoprotein E inhibits neointimal hyperplasia after arterial injury in mice.
The American journal of pathology 2000;157(6):1839-48.
2000: Ying Sun; Peng Jin; David P Witte; Gregory A Grabowski
Prosaposin: promoter analysis and central-nervous-system-preferential elements for expression in vivo.
The Biochemical journal 2000;352 Pt 2():549-56.
2000: L McLaughlin; G Zhu; Meenakshi J Mistry; Cathy Ley-Ebert; William D Stuart; C J Florio; Pam Groen; Sandra A Witt; Thomas R Kimball; David P Witte; Judith A K Harmony; Bruce Aronow
Apolipoprotein J/clusterin limits the severity of murine autoimmune myocarditis.
The Journal of clinical investigation 2000;106(9):1105-13.
2000: Clark D West; AJ McAdams; David P Witte
Acute non-proliferative glomerulitis: a cause of renal failure unique to children.
Pediatric nephrology (Berlin, Germany) 2000;14(8-9):786-93.
2000: Dennis W McGraw; SL Forbes; J C Mak; David P Witte; patricia carrigan; George Leikauf; Stephen B Liggett
Transgenic overexpression of beta(2)-adrenergic receptors in airway epithelial cells decreases bronchoconstriction.
American journal of physiology. Lung cellular and molecular physiology 2000;279(2):L379-89.
2000: Kris A Steinbrecher; Thérèse Tuohy; Kathleen Heppner Goss; M Cathy Scott; David P Witte; Joanna Groden; Mitchell B Cohen
Expression of guanylin is downregulated in mouse and human intestinal adenomas.
Biochemical and biophysical research communications 2000;273(1):225-30.
1999: Jorge A Bezerra; Thomas H Bugge; Hector Melin-Aldana; Gregg E Sabla; Keith W Kombrinck; David P Witte; Jay L Degen
Plasminogen deficiency leads to impaired remodeling after a toxic injury to the liver.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(26):15143-8.
1999: Dennis W McGraw; SL Forbes; Lisa A Kramer; David P Witte; CN Fortner; Richard J Paul; Stephen B Liggett
Transgenic overexpression of beta(2)-adrenergic receptors in airway smooth muscle alters myocyte function and ablates bronchial hyperreactivity.
The Journal of biological chemistry 1999;274(45):32241-7.
1999: Eric W Brunskill; David P Witte; A B Shreiner; steven potter
Characterization of npas3, a novel basic helix-loop-helix PAS gene expressed in the developing mouse nervous system.
Mechanisms of development 1999;88(2):237-41.
1999: RS Muraoka; William Y Sun; Melissa C Colbert; Susan E Waltz; David P Witte; Jay L Degen; S J Friezner Degen
The Ron/STK receptor tyrosine kinase is essential for peri-implantation development in the mouse.
The Journal of clinical investigation 1999;103(9):1277-85.
1999: Elvira Ponce; David P Witte; Rochelle Hirschhorn; Maryann L Huie; Gregory A Grabowski
Murine acid alpha-glucosidase: cell-specific mRNA differential expression during development and maturation.
The American journal of pathology 1999;154(4):1089-96.
1999: K C Ess; David P Witte; C P Bascomb; Bruce Aronow
Diverse developing mouse lineages exhibit high-level c-Myb expression in immature cells and loss of expression upon differentiation.
Oncogene 1999;18(4):1103-11.
1998: Ying Sun; Peng Jin; David P Witte; Gregory A Grabowski
Isolation and characterization of the human prosaposin promoter.
Gene 1998;218(1-2):37-47.
1998: William Y Sun; David P Witte; Jay L Degen; Melissa C Colbert; MC Burkart; K Holmbäck; Q Xiao; Thomas H Bugge; Sandra J F Degen
Prothrombin deficiency results in embryonic and neonatal lethality in mice.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(13):7597-602.
1998: Thomas H Bugge; Leif R Lund; K K Kombrinck; Boye Nielsen; K Holmbäck; Angela F Drew; Matthew J Flick; David P Witte; Keld Danø; Jay L Degen
Reduced metastasis of Polyoma virus middle T antigen-induced mammary cancer in plasminogen-deficient mice.
Oncogene 1998;16(24):3097-104.
1998: J Wang; W Niu; David P Witte; Steven D Chernausek; Yuri E Nikiforov; Thomas Landes Clemens; Behrooz G Sharifi; AR Strauch; James A Fagin
Overexpression of insulin-like growth factor-binding protein-4 (IGFBP-4) in smooth muscle cells of transgenic mice through a smooth muscle alpha-actin-IGFBP-4 fusion gene induces smooth muscle hypoplasia.
Endocrinology 1998;139(5):2605-14.
1998: Q Xiao; Mary Jo Danton; David P Witte; Mark C Kowala; Maria T Valentine; Jay L Degen
Fibrinogen deficiency is compatible with the development of atherosclerosis in mice.
The Journal of clinical investigation 1998;101(5):1184-94.
1998: Mitchell B Cohen; Jennifer A Hawkins; David P Witte
Guanylin mRNA expression in human intestine and colorectal adenocarcinoma.
Laboratory investigation; a journal of technical methods and pathology 1998;78(1):101-8.
1997: Thomas H Bugge; Keith W Kombrinck; Q Xiao; K Holmbäck; CC Daugherty; David P Witte; Jay L Degen
Growth and dissemination of Lewis lung carcinoma in plasminogen-deficient mice.
Blood 1997;90(11):4522-31.
1997: J C Szucsik; David P Witte; H Li; S K Pixley; K M Small; steven potter
Altered forebrain and hindbrain development in mice mutant for the Gsh-2 homeobox gene.
Developmental biology 1997;191(2):230-42.
1997: Q Xiao; Mary Jo Danton; David P Witte; Mark C Kowala; Maria T Valentine; Thomas H Bugge; Jay L Degen
Plasminogen deficiency accelerates vessel wall disease in mice predisposed to atherosclerosis.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(19):10335-40.
1997: TL Whitaker; David P Witte; M Cathy Scott; Mitchell B Cohen
Uroguanylin and guanylin: distinct but overlapping patterns of messenger RNA expression in mouse intestine.
Gastroenterology 1997;113(3):1000-6.
1997: Jie Li; David P Witte; Terry Van Dyke; David S Askew
Expression of the putative proto-oncogene His-1 in normal and neoplastic tissues.
The American journal of pathology 1997;150(4):1297-305.
1996: T L Brown; B C Moulton; David P Witte; Debi K Swertfeger; Judith A K Harmony
Apolipoprotein J/clusterin expression defines distinct stages of blastocyst implantation in the mouse uterus.
Biology of reproduction 1996;55(4):740-7.
1996: Thomas H Bugge; Q Xiao; Keith W Kombrinck; M J Flick; K Holmbäck; Mary Jo Danton; Melissa C Colbert; David P Witte; K Fujikawa; E W Davie; Jay L Degen
Fatal embryonic bleeding events in mice lacking tissue factor, the cell-associated initiator of blood coagulation.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(13):6258-63.
1996: DM Supp; David P Witte; William W Branford Jr; E P Smith; steven potter
Sp4, a member of the Sp1-family of zinc finger transcription factors, is required for normal murine growth, viability, and male fertility.
Developmental biology 1996;176(2):284-99.
1996: Debi K Swertfeger; David P Witte; William D Stuart; H A Rockman; Judith A K Harmony
Apolipoprotein J/clusterin induction in myocarditis: A localized response gene to myocardial injury.
The American journal of pathology 1996;148(6):1971-83.
1996: Hong Du; David P Witte; Gregory A Grabowski
Tissue and cellular specific expression of murine lysosomal acid lipase mRNA and protein.
Journal of lipid research 1996;37(5):937-49.
1996: David P Witte; Bruce Aronow; Judith A K Harmony
Understanding cardiac development through the perspective of gene regulation and gene manipulation.
Pediatric pathology & laboratory medicine : journal of the Society for Pediatric Pathology, affiliated with the International Paediatric Pathology Association 1996;16(2):173-94.
1996: J J Hutton; K C Ess; David P Witte; Bruce Aronow
Winner of the Theodore E. Woodward Award: c-Myb and the coordinate regulation of thymic genes.
Transactions of the American Clinical and Climatological Association 1996;107():115-24.
1995: K C Ess; T L Whitaker; G J Cost; David P Witte; J J Hutton; Bruce Aronow
A central role for a single c-Myb binding site in a thymic locus control region.
Molecular and cellular biology 1995;15(10):5707-15.
1995: Allan Peter Davis; David P Witte; Hsiu Mei Hsieh-Li; steven potter; Mario R Capecchi
Absence of radius and ulna in mice lacking hoxa-11 and hoxd-11.
Nature 1995;375(6534):791-5.
1995: Hsiu Mei Hsieh-Li; David P Witte; M Weinstein; William W Branford Jr; H Li; K Small; steven potter
Hoxa 11 structure, extensive antisense transcription, and function in male and female fertility.
Development (Cambridge, England) 1995;121(5):1373-85.
1995: D J Reeder; William D Stuart; David P Witte; T L Brown; Judith A K Harmony
Local synthesis of apolipoprotein J in the eye.
Experimental eye research 1995;60(5):495-504.
1995: Mitchell B Cohen; David P Witte; J A Hawkins; M G Currie
Immunohistochemical localization of guanylin in the rat small intestine and colon.
Biochemical and biophysical research communications 1995;209(3):803-8.
1995: Hsiu Mei Hsieh-Li; David P Witte; J C Szucsik; M Weinstein; H Li; steven potter
Gsh-2, a murine homeobox gene expressed in the developing brain.
Mechanisms of development 1995;50(2-3):177-86.
1995: Bruce Aronow; C A Ebert; Michael T Valerius; steven potter; Dan A Wiginton; David P Witte; J J Hutton
Dissecting a locus control region: facilitation of enhancer function by extended enhancer-flanking sequences.
Molecular and cellular biology 1995;15(2):1123-35.
1994: Ying Sun; David P Witte; Gregory A Grabowski
Developmental and tissue-specific expression of prosaposin mRNA in murine tissues.
The American journal of pathology 1994;145(6):1390-8.
1994: David P Witte; Bruce Aronow; J K Dry; Judith A K Harmony
Temporally and spatially restricted expression of apolipoprotein J in the developing heart defines discrete stages of valve morphogenesis.
Developmental dynamics : an official publication of the American Association of Anatomists 1994;201(3):290-6.
1994: David P Witte; K E Bove
Beckwith-Wiedemann syndrome and the insulin-like growth factor-II gene. Does the genotype explain the phenotype?
The American journal of pathology 1994;145(4):762-5.
1994: H Li; David P Witte; William W Branford Jr; Bruce Aronow; M Weinstein; S Kaur; S Wert; G Singh; C M Schreiner; J A Whitsett
Gsh-4 encodes a LIM-type homeodomain, is expressed in the developing central nervous system and is required for early postnatal survival.
The EMBO journal 1994;13(12):2876-85.
1994: T C Jordan-Starck; S D Lund; David P Witte; Bruce Aronow; C A Ley; William D Stuart; Debi K Swertfeger; L R Clayton; S F Sells; B Paigen
Mouse apolipoprotein J: characterization of a gene implicated in atherosclerosis.
Journal of lipid research 1994;35(2):194-210.
1993: L G Lewis; David P Witte; D W Laney; M G Currie; Mitchell B Cohen
Guanylin mRNA is expressed in villous enterocytes of the rat small intestine and superficial epithelia of the rat colon.
Biochemical and biophysical research communications 1993;196(2):553-60.
1993: T R Welch; L S Beischel; David P Witte
Differential expression of complement C3 and C4 in the human kidney.
The Journal of clinical investigation 1993;92(3):1451-8.
1993: David P Witte; Bruce Aronow; M L Stauderman; William D Stuart; M A Clay; Ralph A Gruppo; S H Jenkins; Judith A K Harmony
Platelet activation releases megakaryocyte-synthesized apolipoprotein J, a highly abundant protein in atheromatous lesions.
The American journal of pathology 1993;143(3):763-73.
1993: Jorge A Bezerra; David P Witte; Bruce Aronow; Sandra J F Degen
Hepatocyte-specific expression of the mouse hepatocyte growth factor-like protein.
Hepatology (Baltimore, Md.) 1993;18(2):394-9.
1993: Bruce Aronow; S D Lund; T L Brown; Judith A K Harmony; David P Witte
Apolipoprotein J expression at fluid-tissue interfaces: potential role in barrier cytoprotection.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(2):725-9.
1992: Michael J Kern; David P Witte; Michael T Valerius; Bruce Aronow; steven potter
A novel murine homeobox gene isolated by a tissue specific PCR cloning strategy.
Nucleic acids research 1992;20(19):5189-95.
1992: C L Jones; David P Witte; M J Feller; D A Fugman; Gerald W Dorn; M A Lieberman
Response of a human megakaryocytic cell line to thrombin: increase in intracellular free calcium and mitogen release.
Biochimica et biophysica acta 1992;1136(3):272-82.
1992: David P Witte; Bruce Aronow; Judith A K Harmony
Molecular and histological analysis of embryonic development.
Perspectives in pediatric pathology 1992;16():7-26.
1991: David P Witte; T R Welch; L S Beischel
Detection and cellular localization of human C4 gene expression in the renal tubular epithelial cells and other extrahepatic epithelial sources.
The American journal of pathology 1991;139(4):717-24.
1991: David P Witte; Dan A Wiginton; J J Hutton; Bruce Aronow
Coordinate developmental regulation of purine catabolic enzyme expression in gastrointestinal and postimplantation reproductive tracts.
The Journal of cell biology 1991;115(1):179-90.
1990: D A Fugman; David P Witte; C L Jones; Bruce Aronow; M A Lieberman
In vitro establishment and characterization of a human megakaryoblastic cell line.
Blood 1990;75(6):1252-61.
1989: David P Witte; T Nagasaki; Peter J Stambrook; M A Lieberman
Identification of an acidic fibroblast growth factor-like activity in a mesoblastic nephroma.
Laboratory investigation; a journal of technical methods and pathology 1989;60(3):353-9.
1988: David P Witte; Peter J Stambrook; E Feliciano; C L Jones; M A Lieberman
Growth factor production by a human megakaryocytic tumor cell line.
Journal of cellular physiology 1988;137(1):86-94.