FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Wolfgang Wohlleben

Research Profile

Living Beings

Concepts & Ideas

Molecular Sequence Data

Chemicals & Drugs

Genes & Molecular Sequences

Physiology

Procedures

Co-author Network

Publications

TOP 3
Alberto Sola-Landa; Wolfgang Wohlleben; Rafat Amin; Antonio Rodríguez-García; Juan F Martín
Competition between the GlnR and PhoP regulators for the glnA and amtB promoters in Streptomyces coelicolor.
Ewelina Michta; Regina Ort-Winklbauer; Marc Röttig; Klaus Schad; Eva Schinko; Wolfgang Wohlleben; Kai Blin; Oliver Kohlbacher; Yvonne Mast
The bifunctional role of aconitase in Streptomyces viridochromogenes Tü494.
Wolfgang Wohlleben; Yvonne Mast; Günther Muth; Marlene Röttgen; Efthimia Stegmann; Tilmann Weber
Synthetic biology of secondary metabolite biosynthesis in actinomycetes: Engineering precursor supply as a way to optimize antibiotic production.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Wolfgang Wohlleben (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Alberto Sola-Landa; Wolfgang Wohlleben; Rafat Amin; Antonio Rodríguez-García; Juan F Martín
Competition between the GlnR and PhoP regulators for the glnA and amtB promoters in Streptomyces coelicolor.
Nucleic acids research 2013;41(3):1767-82.
2012: Ewelina Michta; Regina Ort-Winklbauer; Marc Röttig; Klaus Schad; Eva Schinko; Wolfgang Wohlleben; Kai Blin; Oliver Kohlbacher; Yvonne Mast
The bifunctional role of aconitase in Streptomyces viridochromogenes Tü494.
Environmental microbiology 2012;14(12):3203-19.
2012: Wolfgang Wohlleben; Yvonne Mast; Günther Muth; Marlene Röttgen; Efthimia Stegmann; Tilmann Weber
Synthetic biology of secondary metabolite biosynthesis in actinomycetes: Engineering precursor supply as a way to optimize antibiotic production.
FEBS letters 2012;586(15):2171-6.
2012: Rafat Amin; Agnieszka Bera; Jens Reuther; Wolfgang Wohlleben; Yvonne Mast
A novel GlnR target gene, nnaR, is involved in nitrate/nitrite assimilation in Streptomyces coelicolor.
Microbiology (Reading, England) 2012;158(Pt 5):1172-82.
2012: Louise Thomas; Elizabeth M H Wellington; Alexander Wentzel; Wolfgang Wohlleben; Nigel J Burroughs; Trond E Ellingsen; David A Hodgson; Roxane Legaie; Juan F Martín; Jonathan Moore; Edward R Morrissey; Kay Nieselt; Antonio Rodríguez-García; Margaret C M Smith
Metabolic switches and adaptations deduced from the proteomes of Streptomyces coelicolor wild type and phoP mutant grown in batch culture.
Molecular & cellular proteomics : MCP 2012;11(2):M111.013797.
2011: Eva Waldvogel; Alexander Wentzel; Wolfgang Wohlleben; Merle Nentwich; Kay Nieselt; Rafat Amin; Florian Battke; Trond E Ellingsen; Alexander Herbig; David A Hodgson; Yvonne Mast
The PII protein GlnK is a pleiotropic regulator for morphological differentiation and secondary metabolism in Streptomyces coelicolor.
Applied microbiology and biotechnology 2011;92(6):1219-36.
2011: Eva-Maria Kleinschnitz; Annette Latus; Iris Maldener; Steffen Sigle; Wolfgang Wohlleben; Günther Muth
Genetic analysis of SCO2997, encoding a TagF homologue, indicates a role for wall teichoic acids in sporulation of Streptomyces coelicolor A3(2).
Journal of bacteriology 2011;193(21):6080-5.
2011: Till F Schäberle; Waldemar Vollmer; Anna-Katharina von Thaler; Wolfgang Wohlleben; Hans-Jörg Frasch; Stephan Hüttel; Andreas Kulik; Marlene Röttgen; Evi Stegmann
Self-resistance and cell wall composition in the glycopeptide producer Amycolatopsis balhimycina.
Antimicrobial agents and chemotherapy 2011;55(9):4283-9.
2011: Yvonne J Mast; Wolfgang Wohlleben; Eva Schinko
Identification and functional characterization of phenylglycine biosynthetic genes involved in pristinamycin biosynthesis in Streptomyces pristinaespiralis.
Journal of biotechnology 2011;155(1):63-7.
2011: Jutta Vogelmann; Moritz Ammelburg; Constanze Finger; Jamil Guezguez; Dirk Linke; Matthias Floetenmeyer; York-Dieter Stierhof; Wolfgang Wohlleben; Günther Muth
Conjugal plasmid transfer in Streptomyces resembles bacterial chromosome segregation by FtsK/SpoIIIE.
The EMBO journal 2011;30(11):2246-54.
2011: Marina Pavlidou; Eva Karoline Pross; Ewa Maria Musiol; Andreas Kulik; Wolfgang Wohlleben; Tilmann Weber
The phosphopantetheinyl transferase KirP activates the ACP and PCP domains of the kirromycin NRPS/PKS of Streptomyces collinus Tü 365.
FEMS microbiology letters 2011;319(1):26-33.
2011: Ewa M Musiol; Thomas Härtner; Andreas Kulik; Jana Moldenhauer; Jörn Piel; Wolfgang Wohlleben; Tilmann Weber
Supramolecular templating in kirromycin biosynthesis: the acyltransferase KirCII loads ethylmalonyl-CoA extender onto a specific ACP of the trans-AT PKS.
Chemistry & biology 2011;18(4):438-44.
2011: Andrea Heichlinger; Moritz Ammelburg; Eva-Maria Kleinschnitz; Annette Latus; Iris Maldener; Klas Flärdh; Wolfgang Wohlleben; Günther Muth
The MreB-like protein Mbl of Streptomyces coelicolor A3(2) depends on MreB for proper localization and contributes to spore wall synthesis.
Journal of bacteriology 2011;193(7):1533-42.
2011: Yvonne Mast; Tilmann Weber; Melanie Gölz; Regina Ort-Winklbauer; Anne Gondran; Wolfgang Wohlleben; Eva Schinko
Characterization of the 'pristinamycin supercluster' of Streptomyces pristinaespiralis.
Microbial biotechnology 2011;4(2):192-206.
2011: Eva-Maria Kleinschnitz; Andrea Heichlinger; Kathrin Schirner; Juliane Winkler; Annette Latus; Iris Maldener; Wolfgang Wohlleben; Günther Muth
Proteins encoded by the mre gene cluster in Streptomyces coelicolor A3(2) cooperate in spore wall synthesis.
Molecular microbiology 2011;79(5):1367-79.
2011: Yvonne Tiffert; Mirita Franz-Wachtel; Claudia Fladerer; Alfred Nordheim; Jens Reuther; Wolfgang Wohlleben; Yvonne Mast
Proteomic analysis of the GlnR-mediated response to nitrogen limitation in Streptomyces coelicolor M145.
Applied microbiology and biotechnology 2011;89(4):1149-59.
2011: F Battke; A Herbig; Alexander Wentzel; O M Jakobsen; Michael Bonin; D A Hodgson; Wolfgang Wohlleben; T E Ellingsen; Kay Nieselt
A technical platform for generating reproducible expression data from Streptomyces coelicolor batch cultivations.
Advances in experimental medicine and biology 2011;696():3-15.
2010: Patricio Lopez; Andreas Hornung; Katrin Welzel; Claudia Unsin; Wolfgang Wohlleben; Tilmann Weber; Stefan Pelzer
Isolation of the lysolipin gene cluster of Streptomyces tendae Tü 4042.
Gene 2010;461(1-2):5-14.
2010: Nina Geib; Tilmann Weber; Tanja Wörtz; Katja Zerbe; Wolfgang Wohlleben; John A Robinson
Genome mining in Amycolatopsis balhimycina for ferredoxins capable of supporting cytochrome P450 enzymes involved in glycopeptide antibiotic biosynthesis.
FEMS microbiology letters 2010;306(1):45-53.
2009: Eva Schinko; Klaus Schad; Sema Eys; Ullrich Keller; Wolfgang Wohlleben
Phosphinothricin-tripeptide biosynthesis: an original version of bacterial secondary metabolism?
Phytochemistry 2009;70(15-16):1787-800.
2009: Kristina J Laiple; Thomas Härtner; Hans-Peter Fiedler; Wolfgang Wohlleben; Tilmann Weber
The kirromycin gene cluster of Streptomyces collinus Tü 365 codes for an aspartate-alpha-decarboxylase, KirD, which is involved in the biosynthesis of the precursor beta-alanine.
The Journal of antibiotics 2009;62(8):465-8.
2009: Tilmann Weber; Christian Rausch; P Lopez; I Hoof; V Gaykova; Daniel H Huson; Wolfgang Wohlleben
CLUSEAN: a computer-based framework for the automated analysis of bacterial secondary metabolite biosynthetic gene clusters.
Journal of biotechnology 2009;140(1-2):13-7.
2009: Wolfgang Wohlleben; Efthimia Stegmann; Roderich D Süssmuth
Chapter 18. Molecular genetic approaches to analyze glycopeptide biosynthesis.
Methods in enzymology 2009;458():459-86.
2008: Meike Chevillotte; Rainer Menges; Günther Muth; Wolfgang Wohlleben; Efthimia Stegmann
A quick and reliable method for monitoring gene expression in actinomycetes.
Journal of biotechnology 2008;135(3):262-5.
2008: Diane Butz; Timo Schmiederer; Bianka Hadatsch; Wolfgang Wohlleben; Tilmann Weber; Roderich D Süssmuth
Module extension of a non-ribosomal peptide synthetase of the glycopeptide antibiotic balhimycin produced by Amycolatopsis balhimycina.
Chembiochem : a European journal of chemical biology 2008;9(8):1195-200.
2008: S Eys; Dirk Schwartz; Wolfgang Wohlleben; E Schinko
Three thioesterases are involved in the biosynthesis of phosphinothricin tripeptide in Streptomyces viridochromogenes Tü494.
Antimicrobial agents and chemotherapy 2008;52(5):1686-96.
2008: Tilmann Weber; Kristina Juliane Laiple; Eva Karoline Pross; Adriana Textor; Stephanie Grond; Katrin Welzel; Stefan Pelzer; Andreas Vente; Wolfgang Wohlleben
Molecular analysis of the kirromycin biosynthetic gene cluster revealed beta-alanine as precursor of the pyridone moiety.
Chemistry & biology 2008;15(2):175-88.
2008: Yvonne Tiffert; Petra Supra; Reinhild Wurm; Wolfgang Wohlleben; Rolf Wagner; Jens Reuther
The Streptomyces coelicolor GlnR regulon: identification of new GlnR targets and evidence for a central role of GlnR in nitrogen metabolism in actinomycetes.
Molecular microbiology 2008;67(4):861-80.
2007: R Menges; Günther Muth; Wolfgang Wohlleben; Efthimia Stegmann
The ABC transporter Tba of Amycolatopsis balhimycina is required for efficient export of the glycopeptide antibiotic balhimycin.
Applied microbiology and biotechnology 2007;77(1):125-34.
2007: Bianka Hadatsch; Diane Butz; Timo Schmiederer; Julia Steudle; Wolfgang Wohlleben; Roderich D Süssmuth; Efthimia Stegmann
The biosynthesis of teicoplanin-type glycopeptide antibiotics: assignment of p450 mono-oxygenases to side chain cyclizations of glycopeptide a47934.
Chemistry & biology 2007;14(9):1078-89.
2007: Yvonne Tiffert; Birke Götz; Jens Reuther; Wolfgang Wohlleben; Günther Muth
Conjugative DNA transfer in Streptomyces: SpdB2 involved in the intramycelial spreading of plasmid pSVH1 is an oligomeric integral membrane protein that binds to dsDNA.
Microbiology (Reading, England) 2007;153(Pt 9):2976-83.
2007: Nai-Hua Hsiao; Johannes Söding; Dirk Linke; Corinna Lange; Christian Hertweck; Wolfgang Wohlleben; Eriko Takano
ScbA from Streptomyces coelicolor A3(2) has homology to fatty acid synthases and is able to synthesize gamma-butyrolactones.
Microbiology (Reading, England) 2007;153(Pt 5):1394-404.
2007: Claudia Müller; S Nolden; Peter Gebhardt; Eva Heinzelmann; C Lange; Oliver Puk; Katrin Welzel; Wolfgang Wohlleben; Dirk Schwartz
Sequencing and analysis of the biosynthetic gene cluster of the lipopeptide antibiotic Friulimicin in Actinoplanes friuliensis.
Antimicrobial agents and chemotherapy 2007;51(3):1028-37.
2007: Riham M Shawky; Oliver Puk; Andreas Wietzorrek; Stefan Pelzer; Eriko Takano; Wolfgang Wohlleben; Efthimia Stegmann
The border sequence of the balhimycin biosynthesis gene cluster from Amycolatopsis balhimycina contains bbr, encoding a StrR-like pathway-specific regulator.
Journal of molecular microbiology and biotechnology 2007;13(1-3):76-88.
2007: Christian Rausch; Ilka Hoof; Tilmann Weber; Wolfgang Wohlleben; Daniel H Huson
Phylogenetic analysis of condensation domains in NRPS sheds light on their functional evolution.
BMC evolutionary biology 2007;7():78.
2007: Jens Reuther; Wolfgang Wohlleben
Nitrogen metabolism in Streptomyces coelicolor: transcriptional and post-translational regulation.
Journal of molecular microbiology and biotechnology 2007;12(1-2):139-46.
2006: Hans-Ulrich Rexer; T Schäberle; Wolfgang Wohlleben; A Engels
Investigation of the functional properties and regulation of three glutamine synthetase-like genes in Streptomyces coelicolor A3(2).
Archives of microbiology 2006;186(6):447-58.
2006: Efthimia Stegmann; Christian Rausch; Sigrid Stockert; Daniel Burkert; Wolfgang Wohlleben
The small MbtH-like protein encoded by an internal gene of the balhimycin biosynthetic gene cluster is not required for glycopeptide production.
FEMS microbiology letters 2006;262(1):85-92.
2006: Efthimia Stegmann; Stefan Pelzer; Daniel Bischoff; Oliver Puk; Sigrid Stockert; Diane Butz; Katja Zerbe; John Robinson; Roderich D Süssmuth; Wolfgang Wohlleben
Genetic analysis of the balhimycin (vancomycin-type) oxygenase genes.
Journal of biotechnology 2006;124(4):640-53.
2006: Jens Reuther; Cordula Gekeler; Yvonne Tiffert; Wolfgang Wohlleben; Günther Muth
Unique conjugation mechanism in mycelial streptomycetes: a DNA-binding ATPase translocates unprocessed plasmid DNA at the hyphal tip.
Molecular microbiology 2006;61(2):436-46.
2006: Paola Mazza; Elke E E Noens; Kathrin Schirner; Nina Grantcharova; A Mieke Mommaas; Henk K Koerten; Günther Muth; Klas Flärdh; Gilles P van Wezel; Wolfgang Wohlleben
MreB of Streptomyces coelicolor is not essential for vegetative growth but is required for the integrity of aerial hyphae and spores.
Molecular microbiology 2006;60(4):838-52.
2006: Jens Reuther; Wolfgang Wohlleben; Günther Muth
Modular architecture of the conjugative plasmid pSVH1 from Streptomyces venezuelae.
Plasmid 2006;55(3):201-9.
2005: Dirk Schwartz; Nicolas Grammel; Eva Heinzelmann; Ullrich Keller; Wolfgang Wohlleben
Phosphinothricin tripeptide synthetases in Streptomyces viridochromogenes Tü494.
Antimicrobial agents and chemotherapy 2005;49(11):4598-607.
2005: Stefano Donadio; Margherita Sosio; Efthimia Stegmann; Tilmann Weber; Wolfgang Wohlleben
Comparative analysis and insights into the evolution of gene clusters for glycopeptide antibiotic biosynthesis.
Molecular genetics and genomics : MGG 2005;274(1):40-50.
2005: Eva Heinzelmann; Susanne Berger; Claudia Müller; Thomas Härtner; Karl Poralla; Wolfgang Wohlleben; Dirk Schwartz
An acyl-CoA dehydrogenase is involved in the formation of the Delta cis3 double bond in the acyl residue of the lipopeptide antibiotic friulimicin in Actinoplanes friuliensis.
Microbiology (Reading, England) 2005;151(Pt 6):1963-74.
2005: Eriko Takano; Hiroshi Kinoshita; Vassilis Mersinias; Giselda Bucca; Graham Hotchkiss; Takuya Nihira; Colin P Smith; Maureen J Bibb; Wolfgang Wohlleben; Keith F Chater
A bacterial hormone (the SCB1) directly controls the expression of a pathway-specific regulatory gene in the cryptic type I polyketide biosynthetic gene cluster of Streptomyces coelicolor.
Molecular microbiology 2005;56(2):465-79.
2005: Daniel Bischoff; Bojan Bister; Marcelo Bertazzo; Volker Pfeifer; Efthimia Stegmann; Graeme J Nicholson; Simone Keller; Stefan Pelzer; Wolfgang Wohlleben; Roderich D Süssmuth
The biosynthesis of vancomycin-type glycopeptide antibiotics--a model for oxidative side-chain cross-linking by oxygenases coupled to the action of peptide synthetases.
Chembiochem : a European journal of chemical biology 2005;6(2):267-72.
2005: Christian Rausch; Tilmann Weber; Oliver Kohlbacher; Wolfgang Wohlleben; Daniel H Huson
Specificity prediction of adenylation domains in nonribosomal peptide synthetases (NRPS) using transductive support vector machines (TSVMs).
Nucleic acids research 2005;33(18):5799-808.
2005: Efthimia Stegmann; Daniel Bischoff; Claudia Kittel; Stefan Pelzer; Oliver Puk; Jürgen Recktenwald; Stefan Weist; Roderich D Süssmuth; Wolfgang Wohlleben
Precursor-directed biosynthesis for the generation of novel glycopetides.
Ernst Schering Research Foundation workshop 2005;(51):215-32.
2004: Dirk Schwartz; Susanne Berger; Eva Heinzelmann; Konstanze Muschko; Katrin Welzel; Wolfgang Wohlleben
Biosynthetic gene cluster of the herbicide phosphinothricin tripeptide from Streptomyces viridochromogenes Tü494.
Applied and environmental microbiology 2004;70(12):7093-102.
2004: Alessandra S Eustáquio; Bertolt Gust; Shu-Ming Li; Stefan Pelzer; Wolfgang Wohlleben; Keith F Chater; Lutz Heide
Production of 8'-halogenated and 8'-unsubstituted novobiocin derivatives in genetically engineered streptomyces coelicolor strains.
Chemistry & biology 2004;11(11):1561-72.
2004: Oliver Puk; Daniel Bischoff; Claudia Kittel; Stefan Pelzer; Stefan Weist; Efthimia Stegmann; Roderich D Süssmuth; Wolfgang Wohlleben
Biosynthesis of chloro-beta-hydroxytyrosine, a nonproteinogenic amino acid of the peptidic backbone of glycopeptide antibiotics.
Journal of bacteriology 2004;186(18):6093-100.
2004: Stefan Weist; Claudia Kittel; Daniel Bischoff; Bojan Bister; Volker Pfeifer; Graeme J Nicholson; Wolfgang Wohlleben; Roderich D Süssmuth
Mutasynthesis of glycopeptide antibiotics: variations of vancomycin's AB-ring amino acid 3,5-dihydroxyphenylglycine.
Journal of the American Chemical Society 2004;126(19):5942-3.
2004: Roderich D Süssmuth; Wolfgang Wohlleben
The biosynthesis of glycopeptide antibiotics--a model for complex, non-ribosomally synthesized, peptidic secondary metabolites.
Applied microbiology and biotechnology 2004;63(4):344-50.
2003: Tilmann Weber; Katrin Welzel; Stefan Pelzer; Andreas Vente; Wolfgang Wohlleben
Exploiting the genetic potential of polyketide producing streptomycetes.
Journal of biotechnology 2003;106(2-3):221-32.
2003: Miroslav Pátek; Günther Muth; Wolfgang Wohlleben
Function of Corynebacterium glutamicum promoters in Escherichia coli, Streptomyces lividans, and Bacillus subtilis.
Journal of biotechnology 2003;104(1-3):325-34.
2003: Bojan Bister; Daniel Bischoff; Graeme J Nicholson; Sigrid Stockert; Joachim Wink; Cristina Brunati; Stefano Donadio; Stefan Pelzer; Wolfgang Wohlleben; Roderich D Süssmuth
Bromobalhimycin and chlorobromobalhimycins--illuminating the potential of halogenases in glycopeptide antibiotic biosyntheses.
Chembiochem : a European journal of chemical biology 2003;4(7):658-62.
2003: Eva Heinzelmann; Susanne Berger; Oliver Puk; B Reichenstein; Wolfgang Wohlleben; Dirk Schwartz
A glutamate mutase is involved in the biosynthesis of the lipopeptide antibiotic friulimicin in Actinoplanes friuliensis.
Antimicrobial agents and chemotherapy 2003;47(2):447-57.
2002: Katja Zerbe; Olena Pylypenko; Francesca Vitali; Weiwen Zhang; Severine Rouset; Markus Heck; Jan W Vrijbloed; Daniel Bischoff; Bojan Bister; Roderich D Süssmuth; Stefan Pelzer; Wolfgang Wohlleben; John A Robinson; Ilme Schlichting
Crystal structure of OxyB, a cytochrome P450 implicated in an oxidative phenol coupling reaction during vancomycin biosynthesis.
The Journal of biological chemistry 2002;277(49):47476-85.
2002: Konstanze Muschko; Grit Kienzlen; Hans-Peter Fiedler; Wolfgang Wohlleben; Dirk Schwartz
Tricarboxylic acid cycle aconitase activity during the life cycle of Streptomyces viridochromogenesTü494.
Archives of microbiology 2002;178(6):499-505.
2002: Wolfgang Wohlleben; Stefan Pelzer
New compounds by combining "modern" genomics and "old-fashioned" mutasynthesis.
Chemistry & biology 2002;9(11):1163-4.
2002: D Fink; N Weissschuh; Jens Reuther; Wolfgang Wohlleben; A Engels
Two transcriptional regulators GlnR and GlnRII are involved in regulation of nitrogen metabolism in Streptomyces coelicolor A3(2).
Molecular microbiology 2002;46(2):331-47.
2002: Andy Hesketh; D Fink; Bertolt Gust; Hans-Ulrich Rexer; B Scheel; Keith F Chater; Wolfgang Wohlleben; A Engels
The GlnD and GlnK homologues of Streptomyces coelicolor A3(2) are functionally dissimilar to their nitrogen regulatory system counterparts from enteric bacteria.
Molecular microbiology 2002;46(2):319-30.
2002: Stefan Weist; Bojan Bister; Oliver Puk; Daniel Bischoff; Stefan Pelzer; Graeme J Nicholson; Wolfgang Wohlleben; Günther Jung; Roderich D Süssmuth
Fluorobalhimycin--a new chapter in glycopeptide antibiotic research.
Angewandte Chemie (International ed. in English) 2002;41(18):3383-5.
2002: Jürgen Recktenwald; Riham M Shawky; Oliver Puk; Frank Pfennig; Ulrich Keller; Wolfgang Wohlleben; Stefan Pelzer
Nonribosomal biosynthesis of vancomycin-type antibiotics: a heptapeptide backbone and eight peptide synthetase modules.
Microbiology (Reading, England) 2002;148(Pt 4):1105-18.
2002: Oliver Puk; Petra Huber; Daniel Bischoff; Jürgen Recktenwald; Günther Jung; Roderich D Süssmuth; Karl-Heinz van Pée; Wolfgang Wohlleben; Stefan Pelzer
Glycopeptide biosynthesis in Amycolatopsis mediterranei DSM5908: function of a halogenase and a haloperoxidase/perhydrolase.
Chemistry & biology 2002;9(2):225-35.
2001: Efthimia Stegmann; Stefan Pelzer; K Wilken; Wolfgang Wohlleben
Development of three different gene cloning systems for genetic investigation of the new species Amycolatopsis japonicum MG417-CF17, the ethylenediaminedisuccinic acid producer.
Journal of biotechnology 2001;92(2):195-204.
2001: Volker Pfeifer; Graeme J Nicholson; J Ries; Jürgen Recktenwald; Alexandre Bezerra Schefer; Riham M Shawky; J Schröder; Wolfgang Wohlleben; Stefan Pelzer
A polyketide synthase in glycopeptide biosynthesis: the biosynthesis of the non-proteinogenic amino acid (S)-3,5-dihydroxyphenylglycine.
The Journal of biological chemistry 2001;276(42):38370-7.
2001: Rolf Tünnemann; Martin Mehlmann; Roderich D Süssmuth; B Bühler; Stefan Pelzer; Wolfgang Wohlleben; Hans-Peter Fiedler; K H Wiesmüller; Günter Gauglitz; Günther Jung
Optical biosensors. Monitoring studies of glycopeptide antibiotic fermentation using white light interference.
Analytical chemistry 2001;73(17):4313-8.
2001: Eva Heinzelmann; Grit Kienzlen; S Kaspar; Jürgen Recktenwald; Wolfgang Wohlleben; Dirk Schwartz
The phosphinomethylmalate isomerase gene pmi, encoding an aconitase-like enzyme, is involved in the synthesis of phosphinothricin tripeptide in Streptomyces viridochromogenes.
Applied and environmental microbiology 2001;67(8):3603-9.
2001: S Vierling; Tilmann Weber; Wolfgang Wohlleben; Günther Muth
Evidence that an additional mutation is required to tolerate insertional inactivation of the Streptomyces lividans recA gene.
Journal of bacteriology 2001;183(14):4374-81.
2000: Nicole Weisschuh; D Fink; S Vierling; Maureen J Bibb; Wolfgang Wohlleben; A Engels
Transcriptional analysis of the gene for glutamine synthetase II and two upstream genes in Streptomyces coelicolor A3(2).
Molecular & general genetics : MGG 2000;264(4):461-9.
2000: A Burger; K Sichler; G Kelemen; M Buttner; Wolfgang Wohlleben
Identification and characterization of the mre gene region of Streptomyces coelicolor A3(2).
Molecular & general genetics : MGG 2000;263(6):1053-60.
2000: S Vierling; Tilmann Weber; Wolfgang Wohlleben; Günther Muth
Transcriptional and mutational analyses of the Streptomyces lividans recX gene and its interference with RecA activity.
Journal of bacteriology 2000;182(14):4005-11.
1999: Dirk Schwartz; S Kaspar; Grit Kienzlen; Konstanze Muschko; Wolfgang Wohlleben
Inactivation of the tricarboxylic acid cycle aconitase gene from Streptomyces viridochromogenes Tü494 impairs morphological and physiological differentiation.
Journal of bacteriology 1999;181(22):7131-5.
1999: D Fink; D Falke; Wolfgang Wohlleben; A Engels
Nitrogen metabolism in Streptomyces coelicolor A3(2): modification of glutamine synthetase I by an adenylyltransferase.
Microbiology (Reading, England) 1999;145 ( Pt 9)():2313-22.
1999: Stefan Pelzer; Roderich D Süssmuth; D Heckmann; Jürgen Recktenwald; P Huber; Günther Jung; Wolfgang Wohlleben
Identification and analysis of the balhimycin biosynthetic gene cluster and its use for manipulating glycopeptide biosynthesis in Amycolatopsis mediterranei DSM5908.
Antimicrobial agents and chemotherapy 1999;43(7):1565-73.
1998: R M Maas; J Götz; Wolfgang Wohlleben; Günther Muth
The conjugative plasmid pSG5 from Streptomyces ghanaensis DSM 2932 differs in its transfer functions from other Streptomyces rolling-circle-type plasmids.
Microbiology (Reading, England) 1998;144 ( Pt 10)():2809-17.
1998: Dirk Schwartz; Jürgen Recktenwald; Stefan Pelzer; Wolfgang Wohlleben
Isolation and characterization of the PEP-phosphomutase and the phosphonopyruvate decarboxylase genes from the phosphinothricin tripeptide producer Streptomyces viridochromogenes Tü494.
FEMS microbiology letters 1998;163(2):149-57.
1998: A Burger; B Brandt; U Süsstrunk; C J Thompson; Wolfgang Wohlleben
Analysis of a Streptomyces coelicolor A3(2) locus containing the nucleoside diphosphate kinase (ndk) and folylpolyglutamate synthetase (folC) genes.
FEMS microbiology letters 1998;159(2):283-91.
1998: Nicolas Grammel; Dirk Schwartz; Wolfgang Wohlleben; Ullrich Keller
Phosphinothricin-tripeptide synthetases from Streptomyces viridochromogenes.
Biochemistry 1998;37(6):1596-603.
1997: Stefan Pelzer; W Reichert; M Huppert; D Heckmann; Wolfgang Wohlleben
Cloning and analysis of a peptide synthetase gene of the balhimycin producer Amycolatopsis mediterranei DSM5908 and development of a gene disruption/replacement system.
Journal of biotechnology 1997;56(2):115-28.
1997: Günther Muth; D Frese; A Kleber; Wolfgang Wohlleben
Mutational analysis of the Streptomyces lividans recA gene suggests that only mutants with residual activity remain viable.
Molecular & general genetics : MGG 1997;255(4):420-8.
1997: G Labes; Maureen J Bibb; Wolfgang Wohlleben
Isolation and characterization of a strong promoter element from the Streptomyces ghanaensis phage I19 using the gentamicin resistance gene (aacC1) of Tn 1696 as reporter.
Microbiology (Reading, England) 1997;143 ( Pt 5)():1503-12.
1997: B Subramaniam-Niehaus; T Schneider; J W Metzger; Wolfgang Wohlleben
Isolation and analysis of moenomycin and its biosynthetic intermediates from Streptomyces ghanaensis (ATCC 14672) wildtype and selected mutants.
Zeitschrift für Naturforschung. C, Journal of biosciences 1997;52(3-4):217-26.
1996: H Decker; S Gaisser; Stefan Pelzer; P Schneider; L Westrich; Wolfgang Wohlleben; Andreas Bechthold
A general approach for cloning and characterizing dNDP-glucose dehydratase genes from actinomycetes.
FEMS microbiology letters 1996;141(2-3):195-201.
1996: M Brodbeck; A Rohling; Wolfgang Wohlleben; C J Thompson; U Süsstrunk
Nucleoside-diphosphate kinase from Streptomyces coelicolor.
European journal of biochemistry / FEBS 1996;239(1):208-13.
1996: D Schwartz; R Alijah; B Nussbaumer; Stefan Pelzer; Wolfgang Wohlleben
The peptide synthetase gene phsA from Streptomyces viridochromogenes is not juxtaposed with other genes involved in nonribosomal biosynthesis of peptides.
Applied and environmental microbiology 1996;62(2):570-7.
1995: Günther Muth; M Farr; V Hartmann; Wolfgang Wohlleben
Streptomyces ghanaensis plasmid pSG5: nucleotide sequence analysis of the self-transmissible minimal replicon and characterization of the replication mode.
Plasmid 1995;33(2):113-26.
1994: B Nussbaumer; Wolfgang Wohlleben
Identification, isolation and sequencing of the recA gene of Streptomyces lividans TK24.
FEMS microbiology letters 1994;118(1-2):57-63.
1994: Wolfgang Wohlleben; V Hartmann; D Hillemann; K Krey; Günther Muth; B Nussbaumer; Stefan Pelzer
Transfer and establishment of DNA in Streptomyces (a brief review).
Acta microbiologica et immunologica Hungarica 1994;41(4):381-9.
1993: D Hillemann; T Dammann; A Hillemann; Wolfgang Wohlleben
Genetic and biochemical characterization of the two glutamine synthetases GSI and GSII of the phosphinothricyl-alanyl-alanine producer, streptomyces viridochromogenes Tü494.
Journal of general microbiology 1993;139(8):1773-83.
1993: Y Kumada; D R Benson; D Hillemann; T J Hosted; D A Rochefort; C J Thompson; Wolfgang Wohlleben; Y Tateno
Evolution of the glutamine synthetase gene, one of the oldest existing and functioning genes.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(7):3009-13.
1992: W Jäger; A Schäfer; Alfred Pühler; G Labes; Wolfgang Wohlleben
Expression of the Bacillus subtilis sacB gene leads to sucrose sensitivity in the gram-positive bacterium Corynebacterium glutamicum but not in Streptomyces lividans.
Journal of bacteriology 1992;174(16):5462-5.
1992: T Dammann; Wolfgang Wohlleben
A metalloprotease gene from Streptomyces coelicolor 'Müller' and its transcriptional activator, a member of the LysR family.
Molecular microbiology 1992;6(16):2267-78.
1992: Wolfgang Wohlleben; R Alijah; J Dorendorf; D Hillemann; B Nussbaumer; Stefan Pelzer
Identification and characterization of phosphinothricin-tripeptide biosynthetic genes in Streptomyces viridochromogenes.
Gene 1992;115(1-2):127-32.
1991: R Alijah; J Dorendorf; S Talay; Alfred Pühler; Wolfgang Wohlleben
Genetic analysis of the phosphinothricin-tripeptide biosynthetic pathway of Streptomyces viridochromogenes Tü494.
Applied microbiology and biotechnology 1991;34(6):749-55.
1991: D Hillemann; Alfred Pühler; Wolfgang Wohlleben
Gene disruption and gene replacement in Streptomyces via single stranded DNA transformation of integration vectors.
Nucleic acids research 1991;19(4):727-31.
1990: I Behrmann; D Hillemann; Alfred Pühler; E Strauch; Wolfgang Wohlleben
Overexpression of a Streptomyces viridochromogenes gene (glnII) encoding a glutamine synthetase similar to those of eucaryotes confers resistance against the antibiotic phosphinothricyl-alanyl-alanine.
Journal of bacteriology 1990;172(9):5326-34.
1990: G Labes; R Simon; Wolfgang Wohlleben
A rapid method for the analysis of plasmid content and copy number in various Streptomycetes grown on agar plates.
Nucleic acids research 1990;18(8):2197.
1989: Wolfgang Wohlleben; W Arnold; L Bissonnette; A Pelletier; A Tanguay; Paul H Roy; G C Gamboa; G F Barry; E Aubert; J Davies
On the evolution of Tn21-like multiresistance transposons: sequence analysis of the gene (aacC1) for gentamicin acetyltransferase-3-I(AAC(3)-I), another member of the Tn21-based expression cassette.
Molecular & general genetics : MGG 1989;217(2-3):202-8.
1988: Wolfgang Wohlleben; W Arnold; I Broer; D Hillemann; E Strauch; Alfred Pühler
Nucleotide sequence of the phosphinothricin N-acetyltransferase gene from Streptomyces viridochromogenes Tü494 and its expression in Nicotiana tabacum.
Gene 1988;70(1):25-37.
1988: E Strauch; Wolfgang Wohlleben; Alfred Pühler
Cloning of a phosphinothricin N-acetyltransferase gene from Streptomyces viridochromogenes Tü494 and its expression in Streptomyces lividans and Escherichia coli.
Gene 1988;63(1):65-74.
1987: Wolfgang Wohlleben; Alfred Pühler
The Streptomyces ghanaensis low copy plasmid pSG2 and its use for vector construction.
Archives of microbiology 1987;148(4):298-304.
1987: E Strauch; Wolfgang Wohlleben; Alfred Pühler
Development of a plasmid-cloning system for Streptomyces viridochromogenes Tü494.
Journal of basic microbiology 1987;27(8):449-55.