Alan Breier

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Spann Melissa; Lindborg Stacy; Seaman John; Baker Robert; Dunayevich Eduardo; Breier Alan
Bayesian adaptive non-inferiority with safety assessment: retrospective case study to highlight potential benefits and limitations of the approach.
Hawkins Keith A; Keefe Richard S E; Christensen Bruce K; Addington Jean; Woods Scott W; Callahan Jennifer; Zipursky Robert B; Perkins Diana O; Tohen Mauricio; Breier Alan; McGlashan Thomas H
Neuropsychological course in the prodrome and first episode of psychosis: findings from the PRIME North America Double Blind Treatment Study.
Adams David H; Close Sandra; Farmen Mark; Downing Anncatherine M; Breier Alan; Houston John P
Dopamine receptor D3 genotype association with greater acute positive symptom remission with olanzapine therapy in predominately caucasian patients with chronic schizophrenia or schizoaffective disorder.

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All Publications

2009: Spann Melissa; Lindborg Stacy; Seaman John; Baker Robert; Dunayevich Eduardo; Breier Alan
Bayesian adaptive non-inferiority with safety assessment: retrospective case study to highlight potential benefits and limitations of the approach.
Journal of psychiatric research 2009;43(5):561-7.
2008: Hawkins Keith A; Keefe Richard S E; Christensen Bruce K; Addington Jean; Woods Scott W; Callahan Jennifer; Zipursky Robert B; Perkins Diana O; Tohen Mauricio; Breier Alan; McGlashan Thomas H
Neuropsychological course in the prodrome and first episode of psychosis: findings from the PRIME North America Double Blind Treatment Study.
Schizophrenia research 2008;105(1-3):1-9.
2008: Adams David H; Close Sandra; Farmen Mark; Downing Anncatherine M; Breier Alan; Houston John P
Dopamine receptor D3 genotype association with greater acute positive symptom remission with olanzapine therapy in predominately caucasian patients with chronic schizophrenia or schizoaffective disorder.
Human psychopharmacology 2008;23(4):267-74.
2007: Hoffman Ralph E; Woods Scott W; Hawkins Keith A; Pittman Brian; Tohen Mauricio; Preda Adrian; Breier Alan; Glist Jill; Addington Jean; Perkins Diana O; McGlashan Thomas H
Extracting spurious messages from noise and risk of schizophrenia-spectrum disorders in a prodromal population.
The British journal of psychiatry : the journal of mental science 2007;191():355-6.
2007: Houston John P; Adams David H; Kirkwood Sandra C; Farmen Mark; Downing AnnCatherine M; Breier Alan
Neuroreceptor gene polymorphisms and olanzapine depressive symptom response in schizophrenia.
Journal of clinical psychopharmacology 2007;27(5):520-3.
2007: Breier Alan; Alphs Larry; Binneman Brendon
Wayne Fenton's impact on industry.
Schizophrenia bulletin 2007;33(5):1154-5.
2006: Carlson Christopher; Hornbuckle Kenneth; DeLisle Frank; Kryzhanovskaya Ludmila; Breier Alan; Cavazzoni Patrizia
Diabetes mellitus and antipsychotic treatment in the United Kingdom.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2006;16(5):366-75.
2006: McGlashan Thomas H; Zipursky Robert B; Perkins Diana; Addington Jean; Miller Tandy; Woods Scott W; Hawkins Keith A; Hoffman Ralph E; Preda Adrian; Epstein Irvin; Addington Donald; Lindborg Stacy; Trzaskoma Quynh; Tohen Mauricio; Breier Alan
Randomized, double-blind trial of olanzapine versus placebo in patients prodromally symptomatic for psychosis.
The American journal of psychiatry 2006;163(5):790-9.
2006: Keefe Richard S E; Young Carrie A; Rock Stephanie L; Purdon Scot E; Gold James M; Breier Alan;
One-year double-blind study of the neurocognitive efficacy of olanzapine, risperidone, and haloperidol in schizophrenia.
Schizophrenia research 2006;81(1):1-15.
2005: Breier Alan; Berg Paul H; Thakore Jogin H; Naber Dieter; Gattaz Wagner F; Cavazzoni Patrizia; Walker Daniel J; Roychowdhury Suraja M; Kane John M
Olanzapine versus ziprasidone: results of a 28-week double-blind study in patients with schizophrenia.
The American journal of psychiatry 2005;162(10):1879-87.
2005: Breier Alan
Developing drugs for cognitive impairment in schizophrenia.
Schizophrenia bulletin 2005;31(4):816-22.
2005: Chou Kelvin L; Messing Susan; Oakes David; Feldman Peter D; Breier Alan; Friedman Joseph H
Drug-induced psychosis in Parkinson disease: phenomenology and correlations among psychosis rating instruments.
Clinical neuropharmacology 2005;28(5):215-9.
2005: Deberdt Walter G; Dysken Maurice W; Rappaport Stephen A; Feldman Peter D; Young Carrie A; Hay Donald P; Lehman Deborah L; Dossenbach Martin; Degenhardt Elisabeth K; Breier Alan
Comparison of olanzapine and risperidone in the treatment of psychosis and associated behavioral disturbances in patients with dementia.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2005;13(8):722-30.
2005: Silva de Lima Maurício; de Jesus Mari Jair; Breier Alan; Maria Costa Anna; Pondé de Sena Eduardo; Hotopf Matthew
Quality of life in schizophrenia: a multicenter, randomized, naturalistic, controlled trial comparing olanzapine to first-generation antipsychotics.
The Journal of clinical psychiatry 2005;66(7):831-8.
2005: Krystal John H; Abi-Saab Walid; Perry Edward; D'Souza D Cyril; Liu Nianjin; Gueorguieva Ralitza; McDougall Lisa; Hunsberger Tracy; Belger Aysenil; Levine Louise; Breier Alan
Preliminary evidence of attenuation of the disruptive effects of the NMDA glutamate receptor antagonist, ketamine, on working memory by pretreatment with the group II metabotropic glutamate receptor agonist, LY354740, in healthy human subjects.
Psychopharmacology 2005;179(1):303-9.
2005: Haro J M; Edgell E T; Novick D; Alonso J; Kennedy L; Jones P B; Ratcliffe M; Breier A;
Effectiveness of antipsychotic treatment for schizophrenia: 6-month results of the Pan-European Schizophrenia Outpatient Health Outcomes (SOHO) study.
Acta psychiatrica Scandinavica 2005;111(3):220-31.
2005: Deberdt Walter; Winokur Andrew; Cavazzoni Patrizia A; Trzaskoma Quynh N; Carlson Christopher D; Bymaster Frank P; Wiener Karen; Floris Michel; Breier Alan
Amantadine for weight gain associated with olanzapine treatment.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2005;15(1):13-21.
2004: Elman Igor; Rott David; Green Alan I; Langleben Daniel D; Lukas Scott E; Goldstein David S; Breier Alan
Effects of pharmacological doses of 2-deoxyglucose on plasma catecholamines and glucose levels in patients with schizophrenia.
Psychopharmacology 2004;176(3-4):369-75.
2004: Namjoshi Madhav A; Risser Richard; Shi Lizheng; Tohen Mauricio; Breier Alan
Quality of life assessment in patients with bipolar disorder treated with olanzapine added to lithium or valproic acid.
Journal of affective disorders 2004;81(3):223-9.
2004: Mitropoulou Vivian; Goodman Marianne; Sevy Serge; Elman Igor; New Antonia S; Iskander Elisabeth G; Silverman Jeremy M; Breier Alan; Siever Larry J
Effects of acute metabolic stress on the dopaminergic and pituitary-adrenal axis activity in patients with schizotypal personality disorder.
Schizophrenia research 2004;70(1):27-31.
2004: Cavazzoni Patrizia; Mukhopadhyay Nitai; Carlson Christopher; Breier Alan; Buse John
Retrospective analysis of risk factors in patients with treatment-emergent diabetes during clinical trials of antipsychotic medications.
The British journal of psychiatry. Supplement 2004;47():S94-101.
2004: Hawkins K A; Addington J; Keefe R S E; Christensen B; Perkins D O; Zipurksy R; Woods S W; Miller T J; Marquez E; Breier A; McGlashan T H
Neuropsychological status of subjects at high risk for a first episode of psychosis.
Schizophrenia research 2004;67(2-3):115-22.
2004: De Deyn Peter Paul; Carrasco Manuel Martín; Deberdt Walter; Jeandel Claude; Hay Donald P; Feldman Peter D; Young Carrie A; Lehman Deborah L; Breier Alan
Olanzapine versus placebo in the treatment of psychosis with or without associated behavioral disturbances in patients with Alzheimer's disease.
International journal of geriatric psychiatry 2004;19(2):115-26.
2004: Feldman Peter D; Hay Linda K; Deberdt Walter; Kennedy John S; Hutchins David S; Hay Donald P; Hardy Thomas A; Hoffmann Vicki P; Hornbuckle Kenneth; Breier Alan
Retrospective cohort study of diabetes mellitus and antipsychotic treatment in a geriatric population in the United States.
Journal of the American Medical Directors Association 2004;5(1):38-46.
2004: Bitter Istvan; Dossenbach Martin R K; Brook Shlomo; Feldman Peter D; Metcalfe Stephen; Gagiano Carlo A; Füredi János; Bartko György; Janka Zoltan; Banki Csaba M; Kovacs Gabor; Breier Alan;
Olanzapine versus clozapine in treatment-resistant or treatment-intolerant schizophrenia.
Progress in neuro-psychopharmacology & biological psychiatry 2004;28(1):173-80.
2004: Zhao Zhongyun; Namjoshi Madhav; Barber Beth L; Loosbrock Danielle L; Tunis Sandra L; Zhu Baojin; Breier Alan
Economic outcomes associated with switching individuals with schizophrenia between risperidone and olanzapine: findings from a large US claims database.
CNS drugs 2004;18(3):157-64.
2003: Wright Padraig; Lindborg Stacy R; Birkett Martin; Meehan Karena; Jones Barry; Alaka Karla; Ferchland-Howe Iris; Pickard Anne; Taylor Cindy C; Roth John; Battaglia John; Bitter István; Chouinard Guy; Morris Philip L P; Breier Alan
Intramuscular olanzapine and intramuscular haloperidol in acute schizophrenia: antipsychotic efficacy and extrapyramidal safety during the first 24 hours of treatment.
Canadian journal of psychiatry. Revue canadienne de psychiatrie 2003;48(11):716-21.
2003: Sowell Margaret; Mukhopadhyay Nitai; Cavazzoni Patrizia; Carlson Christopher; Mudaliar Sunder; Chinnapongse Sithiphol; Ray Amy; Davis Trent; Breier Alan; Henry Robert R; Dananberg Jamie
Evaluation of insulin sensitivity in healthy volunteers treated with olanzapine, risperidone, or placebo: a prospective, randomized study using the two-step hyperinsulinemic, euglycemic clamp.
The Journal of clinical endocrinology and metabolism 2003;88(12):5875-80.
2003: Tohen Mauricio; Goldberg Joseph F; Gonzalez-Pinto Arrillaga Ana Maria; Azorin Jean M; Vieta Eduard; Hardy-Bayle Marie-Christine; Lawson William B; Emsley Robin A; Zhang Fan; Baker Robert W; Risser Richard C; Namjoshi Madhav A; Evans Angela R; Breier Alan
A 12-week, double-blind comparison of olanzapine vs haloperidol in the treatment of acute mania.
Archives of general psychiatry 2003;60(12):1218-26.
2003: Kennedy J S; Jeste D; Kaiser C J; Golshan S; Maguire G A; Tollefson G; Sanger T; Bymaster F P; Kinon B J; Dossenbach M; Gilmore J A; Breier A
Olanzapine vs haloperidol in geriatric schizophrenia: analysis of data from a double-blind controlled trial.
International journal of geriatric psychiatry 2003;18(11):1013-20.
2003: Tohen Mauricio; Vieta Eduard; Calabrese Joseph; Ketter Terence A; Sachs Gary; Bowden Charles; Mitchell Philip B; Centorrino Franca; Risser Richard; Baker Robert W; Evans Angela R; Beymer Karin; Dube Sanjay; Tollefson Gary D; Breier Alan
Efficacy of olanzapine and olanzapine-fluoxetine combination in the treatment of bipolar I depression.
Archives of general psychiatry 2003;60(11):1079-88.
2003: Hardy Thomas; Breier Alan
Patients on atypical antipsychotic drugs: another high-risk group for type 2 diabetes: response to Lean and Pajonk.
Diabetes care 2003;26(11):3200-1.
2003: Feldman Peter D; Kaiser Christopher J; Kennedy John S; Sutton Virginia K; Tran Pierre V; Tollefson Gary D; Zhang Fan; Breier Alan
Comparison of risperidone and olanzapine in the control of negative symptoms of chronic schizophrenia and related psychotic disorders in patients aged 50 to 65 years.
The Journal of clinical psychiatry 2003;64(9):998-1004.
2003: Elman Igor; Lukas Scott; Shoaf Susan E; Rott David; Adler Caleb; Breier Alan
Effects of acute metabolic stress on the peripheral vasopressinergic system in schizophrenia.
Journal of psychopharmacology (Oxford, England) 2003;17(3):317-23.
2003: Woods Scott W; Breier Alan; Zipursky Robert B; Perkins Diana O; Addington Jean; Miller Tandy J; Hawkins Keith A; Marquez Eva; Lindborg Stacy R; Tohen Mauricio; McGlashan Thomas H
Randomized trial of olanzapine versus placebo in the symptomatic acute treatment of the schizophrenic prodrome.
Biological psychiatry 2003;54(4):453-64.
2003: Arango Celso; Breier Alan; McMahon Robert; Carpenter William T; Buchanan Robert W
The relationship of clozapine and haloperidol treatment response to prefrontal, hippocampal, and caudate brain volumes.
The American journal of psychiatry 2003;160(8):1421-7.
2003: Wright Padraig; Meehan Karena; Birkett Martin; Lindborg Stacy R; Taylor Cindy C; Morris Philip; Breier Alan
A comparison of the efficacy and safety of olanzapine versus haloperidol during transition from intramuscular to oral therapy.
Clinical therapeutics 2003;25(5):1420-8.
2003: Miller T J; Zipursky R B; Perkins D; Addington J; Woods S W; Hawkins K A; Hoffman R; Preda A; Epstein I; Addington D; Lindborg S; Marquez E; Tohen M; Breier A; McGlashan T H
The PRIME North America randomized double-blind clinical trial of olanzapine versus placebo in patients at risk of being prodromally symptomatic for psychosis. II. Baseline characteristics of the "prodromal" sample.
Schizophrenia research 2003;61(1):19-30.
2003: McGlashan T H; Zipursky R B; Perkins D; Addington J; Miller T J; Woods S W; Hawkins K A; Hoffman R; Lindborg S; Tohen M; Breier A
The PRIME North America randomized double-blind clinical trial of olanzapine versus placebo in patients at risk of being prodromally symptomatic for psychosis. I. Study rationale and design.
Schizophrenia research 2003;61(1):7-18.
2003: Cavazzoni Patrizia; Tanaka Yoko; Roychowdhury Suraja M; Breier Alan; Allison David B
Nizatidine for prevention of weight gain with olanzapine: a double-blind placebo-controlled trial.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2003;13(2):81-5.
2003: Buse John B; Cavazzoni Patrizia; Hornbuckle Kenneth; Hutchins David; Breier Alan; Jovanovic Lois
A retrospective cohort study of diabetes mellitus and antipsychotic treatment in the United States.
Journal of clinical epidemiology 2003;56(2):164-70.
2003: Sanger Todd M; Tohen Mauricio; Vieta Eduard; Dunner David L; Bowden Charles L; Calabrese Joseph R; Feldman Peter D; Jacobs Thomas G; Breier Alan
Olanzapine in the acute treatment of bipolar I disorder with a history of rapid cycling.
Journal of affective disorders 2003;73(1-2):155-61.
2002: Breier Alan; Sutton Virginia K; Feldman Peter D; Kadam Deborah L; Ferchland Iris; Wright Padraig; Friedman Joseph H
Olanzapine in the treatment of dopamimetic-induced psychosis in patients with Parkinson's disease.
Biological psychiatry 2002;52(5):438-45.
2002: Shi L; Namjoshi M A; Zhang F; Gandhi G; Edgell E T; Tohen M; Breier A; Haro J M
Olanzapine versus haloperidol in the treatment of acute mania: clinical outcomes, health-related quality of life and work status.
International clinical psychopharmacology 2002;17(5):227-37.
2002: Elman Igor; Goldstein David S; Green Alan I; Eisenhofer Graeme; Folio Carol J; Holmes Courtney S; Pickar David; Breier Alan
Effects of risperidone on the peripheral noradrenegic system in patients with schizophrenia: a comparison with clozapine and placebo.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2002;27(2):293-300.
2002: Sowell Margaret O; Mukhopadhyay Nitai; Cavazzoni Patrizia; Shankar Sudha; Steinberg Helmut O; Breier Alan; Beasley Charles M; Dananberg Jamie
Hyperglycemic clamp assessment of insulin secretory responses in normal subjects treated with olanzapine, risperidone, or placebo.
The Journal of clinical endocrinology and metabolism 2002;87(6):2918-23.
2002: Tohen Mauricio; Baker Robert W; Altshuler Lori L; Zarate Carlos A; Suppes Trisha; Ketter Terrence A; Milton Denai R; Risser Richard; Gilmore Julie A; Breier Alan; Tollefson Gary A
Olanzapine versus divalproex in the treatment of acute mania.
The American journal of psychiatry 2002;159(6):1011-7.
2002: Namjoshi Madhav A; Rajamannar Gopalan; Jacobs Thomas; Sanger Todd M; Risser Richard; Tohen Mauricio F; Breier Alan; Keck Paul E
Economic, clinical, and quality-of-life outcomes associated with olanzapine treatment in mania. Results from a randomized controlled trial.
Journal of affective disorders 2002;69(1-3):109-18.
2002: Breier Alan; Meehan Karena; Birkett Martin; David Stacy; Ferchland Iris; Sutton Virginia; Taylor Cindy C; Palmer Rebecca; Dossenbach Martin; Kiesler Geri; Brook Shlomo; Wright Padraig
A double-blind, placebo-controlled dose-response comparison of intramuscular olanzapine and haloperidol in the treatment of acute agitation in schizophrenia.
Archives of general psychiatry 2002;59(5):441-8.
2002: Meehan Karena M; Wang Huei; David Stacy R; Nisivoccia Jennifer R; Jones Barry; Beasley Charles M; Feldman Peter D; Mintzer Jacobo E; Beckett Louise M; Breier Alan
Comparison of rapidly acting intramuscular olanzapine, lorazepam, and placebo: a double-blind, randomized study in acutely agitated patients with dementia.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2002;26(4):494-504.
2002: Adler Caleb M; Malhotra Anil K; Elman Igor; Pickar David; Breier Alan
Amphetamine-induced dopamine release and post-synaptic specific binding in patients with mild tardive dyskinesia.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2002;26(3):295-300.
2002: Tohen Mauricio; Chengappa K N Roy; Suppes Trisha; Zarate Carlos A; Calabrese Joseph R; Bowden Charles L; Sachs Gary S; Kupfer David J; Baker Robert W; Risser Richard C; Keeter Elisabeth L; Feldman Peter D; Tollefson Gary D; Breier Alan
Efficacy of olanzapine in combination with valproate or lithium in the treatment of mania in patients partially nonresponsive to valproate or lithium monotherapy.
Archives of general psychiatry 2002;59(1):62-9.
2001: Tohen M; Zhang F; Keck P E; Feldman P D; Risser R C; Tran P V; Breier A
Olanzapine versus haloperidol in schizoaffective disorder, bipolar type.
Journal of affective disorders 2001;67(1-3):133-40.
2001: Mintzer J; Faison W; Street J S; Sutton V K; Breier A
Olanzapine in the treatment of anxiety symptoms due to Alzheimer's disease: a post hoc analysis.
International journal of geriatric psychiatry 2001;16 Suppl 1():S71-7.
2001: Street J S; Clark W S; Kadam D L; Mitan S J; Juliar B E; Feldman P D; Breier A
Long-term efficacy of olanzapine in the control of psychotic and behavioral symptoms in nursing home patients with Alzheimer's dementia.
International journal of geriatric psychiatry 2001;16 Suppl 1():S62-70.
2001: Kennedy J S; Bymaster F P; Schuh L; Calligaro D O; Nomikos G; Felder C C; Bernauer M; Kinon B J; Baker R W; Hay D; Roth H J; Dossenbach M; Kaiser C; Beasley C M; Holcombe J H; Effron M B; Breier A
A current review of olanzapine's safety in the geriatric patient: from pre-clinical pharmacology to clinical data.
International journal of geriatric psychiatry 2001;16 Suppl 1():S33-61.
2001: Kennedy J S; Zagar A; Bymaster F; Nomikos G; Trzepacz P T; Gilmore J A; Rotelli M D; Breier A; Tollefson G
The central cholinergic system profile of olanzapine compared with placebo in Alzheimer's disease.
International journal of geriatric psychiatry 2001;16 Suppl 1():S24-32.
2001: Meehan K; Zhang F; David S; Tohen M; Janicak P; Small J; Koch M; Rizk R; Walker D; Tran P; Breier A
A double-blind, randomized comparison of the efficacy and safety of intramuscular injections of olanzapine, lorazepam, or placebo in treating acutely agitated patients diagnosed with bipolar mania.
Journal of clinical psychopharmacology 2001;21(4):389-97.
2001: Wright P; Birkett M; David S R; Meehan K; Ferchland I; Alaka K J; Saunders J C; Krueger J; Bradley P; San L; Bernardo M; Reinstein M; Breier A
Double-blind, placebo-controlled comparison of intramuscular olanzapine and intramuscular haloperidol in the treatment of acute agitation in schizophrenia.
The American journal of psychiatry 2001;158(7):1149-51.
2001: Elman I; Goldstein D S; Adler C M; Shoaf S E; Breier A
Inverse relationship between plasma epinephrine and testosterone levels during acute glucoprivation in healthy men.
Life sciences 2001;68(16):1889-98.
2001: Clark W S; Street J S; Feldman P D; Breier A
The effects of olanzapine in reducing the emergence of psychosis among nursing home patients with Alzheimer's disease.
The Journal of clinical psychiatry 2001;62(1):34-40.
2001: Breier A
Introduction: a new era in the pharmacotherapy of psychotic disorders.
The Journal of clinical psychiatry 2001;62 Suppl 2():3-5.
2000: Edgell E T; Andersen S W; Johnstone B M; Dulisse B; Revicki D; Breier A
Olanzapine versus risperidone. A prospective comparison of clinical and economic outcomes in schizophrenia.
PharmacoEconomics 2000;18(6):567-79.
2000: Street J S; Clark W S; Gannon K S; Cummings J L; Bymaster F P; Tamura R N; Mitan S J; Kadam D L; Sanger T M; Feldman P D; Tollefson G D; Breier A
Olanzapine treatment of psychotic and behavioral symptoms in patients with Alzheimer disease in nursing care facilities: a double-blind, randomized, placebo-controlled trial. The HGEU Study Group.
Archives of general psychiatry 2000;57(10):968-76.
2000: Breier A; Buchanan R W; Irish D; Carpenter W T
Clozapine treatment of outpatients with schizophrenia: outcome and long-term response patterns. 1993.
Psychiatric services (Washington, D.C.) 2000;51(10):1249-53.
2000: Carpenter W T; Breier A; Buchanan R W; Kirkpatrick B; Shepard P; Weiner E
Mazindol treatment of negative symptoms.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2000;23(4):365-74.
2000: David S R; Taylor C C; Kinon B J; Breier A
The effects of olanzapine, risperidone, and haloperidol on plasma prolactin levels in patients with schizophrenia.
Clinical therapeutics 2000;22(9):1085-96.
2000: Hamilton S H; Edgell E T; Revicki D A; Breier A
Functional outcomes in schizophrenia: a comparison of olanzapine and haloperidol in a European sample.
International clinical psychopharmacology 2000;15(5):245-55.
2000: Tohen M; Jacobs T G; Grundy S L; McElroy S L; Banov M C; Janicak P G; Sanger T; Risser R; Zhang F; Toma V; Francis J; Tollefson G D; Breier A
Efficacy of olanzapine in acute bipolar mania: a double-blind, placebo-controlled study. The Olanzipine HGGW Study Group.
Archives of general psychiatry 2000;57(9):841-9.
2000: Gómez J C; Sacristán J A; Hernández J; Breier A; Ruiz Carrasco P; Antón Saiz C; Fontova Carbonell E
The safety of olanzapine compared with other antipsychotic drugs: results of an observational prospective study in patients with schizophrenia (EFESO Study). Pharmacoepidemiologic Study of Olanzapine in Schizophrenia.
The Journal of clinical psychiatry 2000;61(5):335-43.
2000: Adler C M; Elman I; Weisenfeld N; Kestler L; Pickar D; Breier A
Effects of acute metabolic stress on striatal dopamine release in healthy volunteers.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2000;22(5):545-50.
2000: Watabe H; Endres C J; Breier A; Schmall B; Eckelman W C; Carson R E
Measurement of dopamine release with continuous infusion of [11C]raclopride: optimization and signal-to-noise considerations.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2000;41(3):522-30.
2000: Purdon S E; Jones B D; Stip E; Labelle A; Addington D; David S R; Breier A; Tollefson G D
Neuropsychological change in early phase schizophrenia during 12 months of treatment with olanzapine, risperidone, or haloperidol. The Canadian Collaborative Group for research in schizophrenia.
Archives of general psychiatry 2000;57(3):249-58.
2000: Bertolino A; Breier A; Callicott J H; Adler C; Mattay V S; Shapiro M; Frank J A; Pickar D; Weinberger D R
The relationship between dorsolateral prefrontal neuronal N-acetylaspartate and evoked release of striatal dopamine in schizophrenia.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2000;22(2):125-32.
2000: Kestler L P; Malhotra A K; Finch C; Adler C; Breier A
The relation between dopamine D2 receptor density and personality: preliminary evidence from the NEO personality inventory-revised.
Neuropsychiatry, neuropsychology, and behavioral neurology 2000;13(1):48-52.
1999: Adler C M; Malhotra A K; Elman I; Goldberg T; Egan M; Pickar D; Breier A
Comparison of ketamine-induced thought disorder in healthy volunteers and thought disorder in schizophrenia.
The American journal of psychiatry 1999;156(10):1646-9.
1999: Breier A; Berg P H
The psychosis of schizophrenia: prevalence, response to atypical antipsychotics, and prediction of outcome.
Biological psychiatry 1999;46(3):361-4.
1999: Kosmidis M H; Breier A; Fantie B D
Avoidance learning in schizophrenia: a dissociation between the effects of aversive and non-aversive stimuli.
Schizophrenia research 1999;38(1):51-9.
1999: Bryant N L; Buchanan R W; Vladar K; Breier A; Rothman M
Gender differences in temporal lobe structures of patients with schizophrenia: a volumetric MRI study.
The American journal of psychiatry 1999;156(4):603-9.
1999: Breier A; Su T P; Malhotra A K; Elman I; Adler C M; Weisenfeld N I; Pickar D
Effects of atypical antipsychotic drug treatment on amphetamine-induced striatal dopamine release in patients with psychotic disorders.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1999;20(4):340-5.
1999: Carpenter W T; Buchanan R W; Kirkpatrick B; Lann H D; Breier A F; Summerfelt A T
Comparative effectiveness of fluphenazine decanoate injections every 2 weeks versus every 6 weeks.
The American journal of psychiatry 1999;156(3):412-8.
1999: Breier A; Hamilton S H
Comparative efficacy of olanzapine and haloperidol for patients with treatment-resistant schizophrenia.
Biological psychiatry 1999;45(4):403-11.
1999: Carpenter W T; Buchanan R W; Kirkpatrick B; Breier A F
Diazepam treatment of early signs of exacerbation in schizophrenia.
The American journal of psychiatry 1999;156(2):299-303.
1999: Breier A F; Malhotra A K; Su T P; Pinals D A; Elman I; Adler C M; Lafargue R T; Clifton A; Pickar D
Clozapine and risperidone in chronic schizophrenia: effects on symptoms, parkinsonian side effects, and neuroendocrine response.
The American journal of psychiatry 1999;156(2):294-8.
1999: Elman I; Goldstein D S; Eisenhofer G; Folio J; Malhotra A K; Adler C M; Pickar D; Breier A
Mechanism of peripheral noradrenergic stimulation by clozapine.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1999;20(1):29-34.
1999: Elman I; Sokoloff L; Adler C M; Weisenfeld N; Breier A
The effects of pharmacological doses of 2-deoxyglucose on cerebral blood flow in healthy volunteers.
Brain research 1999;815(2):243-9.
1999: Breier A
Cognitive deficit in schizophrenia and its neurochemical basis.
The British journal of psychiatry. Supplement 1999;(37):16-8.
1998: Malhotra A K; Breier A; Goldman D; Picken L; Pickar D
The apolipoprotein E epsilon 4 allele is associated with blunting of ketamine-induced psychosis in schizophrenia. A preliminary report.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1998;19(5):445-8.
1998: Breier A; Kestler L; Adler C; Elman I; Wiesenfeld N; Malhotra A; Pickar D
Dopamine D2 receptor density and personal detachment in healthy subjects.
The American journal of psychiatry 1998;155(10):1440-2.
1998: Malhotra A K; Goldman D; Mazzanti C; Clifton A; Breier A; Pickar D
A functional serotonin transporter (5-HTT) polymorphism is associated with psychosis in neuroleptic-free schizophrenics.
Molecular psychiatry 1998;3(4):328-32.
1998: Elman I; Adler C M; Malhotra A K; Bir C; Pickar D; Breier A
Effect of acute metabolic stress on pituitary-adrenal axis activation in patients with schizophrenia.
The American journal of psychiatry 1998;155(7):979-81.
1998: Buchanan R W; Breier A; Kirkpatrick B; Ball P; Carpenter W T
Positive and negative symptom response to clozapine in schizophrenic patients with and without the deficit syndrome.
The American journal of psychiatry 1998;155(6):751-60.
1998: Adler C M; Goldberg T E; Malhotra A K; Pickar D; Breier A
Effects of ketamine on thought disorder, working memory, and semantic memory in healthy volunteers.
Biological psychiatry 1998;43(11):811-6.
1998: Breier A; Adler C M; Weisenfeld N; Su T P; Elman I; Picken L; Malhotra A K; Pickar D
Effects of NMDA antagonism on striatal dopamine release in healthy subjects: application of a novel PET approach.
Synapse (New York, N.Y.) 1998;29(2):142-7.
1998: Bertolino A; Callicott J H; Elman I; Mattay V S; Tedeschi G; Frank J A; Breier A; Weinberger D R
Regionally specific neuronal pathology in untreated patients with schizophrenia: a proton magnetic resonance spectroscopic imaging study.
Biological psychiatry 1998;43(9):641-8.
1998: Pinals D A; Malhotra A K; Breier A; Pickar D
Informed consent in schizophrenia research.
Psychiatric services (Washington, D.C.) 1998;49(2):244.
1998: Malhotra A K; Goldman D; Buchanan R W; Rooney W; Clifton A; Kosmidis M H; Breier A; Pickar D
The dopamine D3 receptor (DRD3) Ser9Gly polymorphism and schizophrenia: a haplotype relative risk study and association with clozapine response.
Molecular psychiatry 1998;3(1):72-5.
1998: Breier A; Elman I; Goldstein D S
Norepinephrine and schizophrenia: a new hypothesis for antipsychotic drug action.
Advances in pharmacology (San Diego, Calif.) 1998;42():785-8.
1997: Kirkpatrick B; Litman D; Kim J W; Vladar K; Breier A; Buchanan R W
Failure of fusion of the septum pellucidum and the heterogeneity of schizophrenia.
The Journal of nervous and mental disease 1997;185(10):639-41.
1997: Su T P; Malhotra A K; Hadd K; Breier A; Pickar D
D2 dopamine receptor occupancy: a crossover comparison of risperidone with clozapine therapy in schizophrenic patients.
Archives of general psychiatry 1997;54(10):972-3.
1997: Malhotra A K; Adler C M; Kennison S D; Elman I; Pickar D; Breier A
Clozapine blunts N-methyl-D-aspartate antagonist-induced psychosis: a study with ketamine.
Biological psychiatry 1997;42(8):664-8.
1997: Pickar D; Malhotra A K; Rooney W; Breier A; Goldman D
Apolipoprotein E epsilon 4 and clinical phenotype in schizophrenia.
Lancet 1997;350(9082):930-1.
1997: Endres C J; Kolachana B S; Saunders R C; Su T; Weinberger D; Breier A; Eckelman W C; Carson R E
Kinetic modeling of [11C]raclopride: combined PET-microdialysis studies.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1997;17(9):932-42.
1997: Malhotra A K; Pinals D A; Adler C M; Elman I; Clifton A; Pickar D; Breier A
Ketamine-induced exacerbation of psychotic symptoms and cognitive impairment in neuroleptic-free schizophrenics.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1997;17(3):141-50.
1997: Breier A; Malhotra A K; Pinals D A; Weisenfeld N I; Pickar D
Association of ketamine-induced psychosis with focal activation of the prefrontal cortex in healthy volunteers.
The American journal of psychiatry 1997;154(6):805-11.
1997: Carson R E; Breier A; de Bartolomeis A; Saunders R C; Su T P; Schmall B; Der M G; Pickar D; Eckelman W C
Quantification of amphetamine-induced changes in [11C]raclopride binding with continuous infusion.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1997;17(4):437-47.
1997: Breier A; Su T P; Saunders R; Carson R E; Kolachana B S; de Bartolomeis A; Weinberger D R; Weisenfeld N; Malhotra A K; Eckelman W C; Pickar D
Schizophrenia is associated with elevated amphetamine-induced synaptic dopamine concentrations: evidence from a novel positron emission tomography method.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(6):2569-74.
1997: Buchanan R W; Strauss M E; Breier A; Kirkpatrick B; Carpenter W T
Attentional impairments in deficit and nondeficit forms of schizophrenia.
The American journal of psychiatry 1997;154(3):363-70.
1997: Waltrip R W; Buchanan R W; Carpenter W T; Kirkpatrick B; Summerfelt A; Breier A; Rubin S A; Carbone K M
Borna disease virus antibodies and the deficit syndrome of schizophrenia.
Schizophrenia research 1997;23(3):253-7.
1997: Elman I; Breier A
Effects of acute metabolic stress on plasma progesterone and testosterone in male subjects: relationship to pituitary-adrenocortical axis activation.
Life sciences 1997;61(17):1705-12.
1996: Pinals D A; Malhotra A K; Missar C D; Pickar D; Breier A
Lack of gender differences in neuroleptic response in patients with schizophrenia.
Schizophrenia research 1996;22(3):215-22.
1996: Buchanan R W; Kirkpatrick B; Bryant N; Ball P; Breier A
Fluoxetine augmentation of clozapine treatment in patients with schizophrenia.
The American journal of psychiatry 1996;153(12):1625-7.
1996: Pickar D; Su T P; Weinberger D R; Coppola R; Malhotra A K; Knable M B; Lee K S; Gorey J; Bartko J J; Breier A; Hsiao J
Individual variation in D2 dopamine receptor occupancy in clozapine-treated patients.
The American journal of psychiatry 1996;153(12):1571-8.
1996: Carpenter W T; Conley R R; Buchanan R W; Breier A; Tamminga C A
Clozapine conflict.
The American journal of psychiatry 1996;153(11):1505-7.
1996: Malhotra A K; Goldman D; Ozaki N; Rooney W; Clifton A; Buchanan R W; Breier A; Pickar D
Clozapine response and the 5HT2C Cys23Ser polymorphism.
Neuroreport 1996;7(13):2100-2.
1996: Malhotra A K; Goldman D; Ozaki N; Breier A; Buchanan R; Pickar D
Lack of association between polymorphisms in the 5-HT2A receptor gene and the antipsychotic response to clozapine.
The American journal of psychiatry 1996;153(8):1092-4.
1996: Frazier J A; Giedd J N; Hamburger S D; Albus K E; Kaysen D; Vaituzis A C; Rajapakse J C; Lenane M C; McKenna K; Jacobsen L K; Gordon C T; Breier A; Rapoport J L
Brain anatomic magnetic resonance imaging in childhood-onset schizophrenia.
Archives of general psychiatry 1996;53(7):617-24.
1996: Malhotra A K; Goldman D; Buchanan R; Breier A; Pickar D
5HT 2a receptor T102C polymorphism and schizophrenia.
Lancet 1996;347(9018):1830-1.
1996: Bustillo J R; Buchanan R W; Irish D; Breier A
Differential effect of clozapine on weight: a controlled study.
The American journal of psychiatry 1996;153(6):817-9.
1996: Malhotra A K; Pinals D A; Weingartner H; Sirocco K; Missar C D; Pickar D; Breier A
NMDA receptor function and human cognition: the effects of ketamine in healthy volunteers.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1996;14(5):301-7.
1996: Frazier J A; Giedd J N; Kaysen D; Albus K; Hamburger S; Alaghband-Rad J; Lenane M C; McKenna K; Breier A; Rapoport J L
Childhood-onset schizophrenia: brain MRI rescan after 2 years of clozapine maintenance treatment.
The American journal of psychiatry 1996;153(4):564-6.
1995: Carpenter W T; Conley R R; Buchanan R W; Breier A; Tamminga C A
Patient response and resource management: another view of clozapine treatment of schizophrenia.
The American journal of psychiatry 1995;152(6):827-32.
1995: Schreiber J L; Breier A; Pickar D
Expressed emotion. Trait or state?
The British journal of psychiatry : the journal of mental science 1995;166(5):647-9.
1995: Breier A
Serotonin, schizophrenia and antipsychotic drug action.
Schizophrenia research 1995;14(3):187-202.
1995: Waltrip R W; Buchanan R W; Summerfelt A; Breier A; Carpenter W T; Bryant N L; Rubin S A; Carbone K M
Borna disease virus and schizophrenia.
Psychiatry research 1995;56(1):33-44.
1994: Buchanan R W; Holstein C; Breier A
The comparative efficacy and long-term effect of clozapine treatment on neuropsychological test performance.
Biological psychiatry 1994;36(11):717-25.
1994: Buchanan R W; Strauss M E; Kirkpatrick B; Holstein C; Breier A; Carpenter W T
Neuropsychological impairments in deficit vs nondeficit forms of schizophrenia.
Archives of general psychiatry 1994;51(10):804-11.
1994: Breier A
Clozapine and noradrenergic function: support for a novel hypothesis for superior efficacy.
The Journal of clinical psychiatry 1994;55 Suppl B():122-5.
1994: Kirkpatrick B; Buchanan R W; Breier A; Carpenter W T
Depressive symptoms and the deficit syndrome of schizophrenia.
The Journal of nervous and mental disease 1994;182(8):452-5.
1994: Buchanan R W; Koeppl P; Breier A
Stability of neurological signs with clozapine treatment.
Biological psychiatry 1994;36(3):198-200.
1994: Elkashef A M; Buchanan R W; Gellad F; Munson R C; Breier A
Basal ganglia pathology in schizophrenia and tardive dyskinesia: an MRI quantitative study.
The American journal of psychiatry 1994;151(5):752-5.
1994: Breier A; Buchanan R W; Waltrip R W; Listwak S; Holmes C; Goldstein D S
The effect of clozapine on plasma norepinephrine: relationship to clinical efficacy.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1994;10(1):1-7.
1994: Breier A; Buchanan R W; Kirkpatrick B; Davis O R; Irish D; Summerfelt A; Carpenter W T
Effects of clozapine on positive and negative symptoms in outpatients with schizophrenia.
The American journal of psychiatry 1994;151(1):20-6.
1993: Breier A; Buchanan R W; Irish D; Carpenter W T
Clozapine treatment of outpatients with schizophrenia: outcome and long-term response patterns.
Hospital & community psychiatry 1993;44(12):1145-9.
1993: Breier A; Kirkpatrick B; Buchanan R W
Clozapine attenuates meta-chlorophenylpiperazine (mCPP)-induced plasma cortisol increases in schizophrenia.
Biological psychiatry 1993;34(7):492-4.
1993: Schreiber J L; Breier A; Pickar D
Hospital vs. community.
Hospital & community psychiatry 1993;44(8):795.
1993: Breier A; Crane A M; Kennedy C; Sokoloff L
The effects of pharmacologic doses of 2-deoxy-D-glucose on local cerebral blood flow in the awake, unrestrained rat.
Brain research 1993;618(2):277-82.
1993: Breier A; Davis O R; Buchanan R W; Moricle L A; Munson R C
Effects of metabolic perturbation on plasma homovanillic acid in schizophrenia. Relationship to prefrontal cortex volume.
Archives of general psychiatry 1993;50(7):541-50.
1993: Wolkowitz O M; Weingartner H; Rubinow D R; Jimerson D; Kling M; Berretini W; Thompson K; Breier A; Doran A; Reus V I
Steroid modulation of human memory: biochemical correlates.
Biological psychiatry 1993;33(10):744-6.
1993: Kirkpatrick B; Buchanan R W; Breier A; Carpenter W T
Case identification and stability of the deficit syndrome of schizophrenia.
Psychiatry research 1993;47(1):47-56.
1993: Buchanan R W; Breier A; Kirkpatrick B; Elkashef A; Munson R C; Gellad F; Carpenter W T
Structural abnormalities in deficit and nondeficit schizophrenia.
The American journal of psychiatry 1993;150(1):59-65.
1993: Wolkowitz O M; Coppola R; Breier A; Doran A R; Rubinow D R; Berrettini W H; Kling M A; Pickar D
Quantitative electroencephalographic correlates of steroid administration in man.
Neuropsychobiology 1993;27(4):224-30.
1993: Hommer D; Weingartner H; Breier A
Dissociation of benzodiazepine-induced amnesia from sedation by flumazenil pretreatment.
Psychopharmacology 1993;112(4):455-60.
1992: Kirkpatrick B; Carpenter W T; Maeda K; Buchanan R W; Breier A; Tamminga C A
Plasma prolactin as a predictor of relapse in drug-free schizophrenic outpatients.
Biological psychiatry 1992;32(11):1049-54.
1992: Breier A; Buchanan R W; Elkashef A; Munson R C; Kirkpatrick B; Gellad F
Brain morphology and schizophrenia. A magnetic resonance imaging study of limbic, prefrontal cortex, and caudate structures.
Archives of general psychiatry 1992;49(12):921-6.
1992: Goldstein D S; Breier A; Wolkowitz O M; Pickar D; Lenders J W
Plasma levels of catecholamines and corticotrophin during acute glucopenia induced by 2-deoxy-D-glucose in normal man.
Clinical autonomic research : official journal of the Clinical Autonomic Research Society 1992;2(6):359-66.
1992: Breier A; Davis O; Buchanan R; Listwak S J; Holmes C; Pickar D; Goldstein D S
Effects of alprazolam on pituitary-adrenal and catecholaminergic responses to metabolic stress in humans.
Biological psychiatry 1992;32(10):880-90.
1992: Breier A; Schreiber J L; Dyer J; Pickar D
Course of illness and predictors of outcome in chronic schizophrenia: implications for pathophysiology.
The British journal of psychiatry. Supplement 1992;(18):38-43.
1992: Albus M; Zahn T P; Breier A
Anxiogenic properties of yohimbine. II. Influence of experimental set and setting.
European archives of psychiatry and clinical neuroscience 1992;241(6):345-51.
1992: Albus M; Zahn T P; Breier A
Anxiogenic properties of yohimbine. I. Behavioral, physiological and biochemical measures.
European archives of psychiatry and clinical neuroscience 1992;241(6):337-44.
1992: Breier A; Buchanan R W
The effects of metabolic stress on plasma progesterone in healthy volunteers and schizophrenic patients.
Life sciences 1992;51(19):1527-34.
1991: Breier A
Panic disorder: clinical features, neurobiology, and pharmacotherapy.
New York state journal of medicine 1991;91(11 Suppl):43S-47S.
1991: Carpenter W T; Buchanan R W; Breier A; Kirkpatrick B; Thaker G; Tamminga C
Psychopathology and the question of neurodevelopmental or neurodegenerative disorder.
Schizophrenia research 1991;5(3):192-4.
1991: Breier A; Schreiber J L; Dyer J; Pickar D
National Institute of Mental Health longitudinal study of chronic schizophrenia. Prognosis and predictors of outcome.
Archives of general psychiatry 1991;48(3):239-46.
1991: Carpenter W T; Kurz R; Kirkpatrick B; Hanlon T E; Summerfelt A T; Buchanan R W; Waltrip R W; Breier A
Carbamazepine maintenance treatment in outpatient schizophrenics.
Archives of general psychiatry 1991;48(1):69-72.
1991: Breier A; Davis O R; Buchanan R W
Alprazolam attenuates metabolic stress-induced neuroendocrine and behavioral effects in humans.
Psychopharmacology 1991;104(4):479-84.
1990: Breier A; Wolkowitz O M; Roy A; Potter W Z; Pickar D
Plasma norepinephrine in chronic schizophrenia.
The American journal of psychiatry 1990;147(11):1467-70.
1990: Wolkowitz O M; Reus V I; Weingartner H; Thompson K; Breier A; Doran A; Rubinow D; Pickar D
Cognitive effects of corticosteroids.
The American journal of psychiatry 1990;147(10):1297-303.
1990: Wolkowitz O M; Rubinow D; Doran A R; Breier A; Berrettini W H; Kling M A; Pickar D
Prednisone effects on neurochemistry and behavior. Preliminary findings.
Archives of general psychiatry 1990;47(10):963-8.
1990: Pickar D; Breier A; Hsiao J K; Doran A R; Wolkowitz O M; Pato C N; Konicki P E; Potter W Z
Cerebrospinal fluid and plasma monoamine metabolites and their relation to psychosis. Implications for regional brain dysfunction in schizophrenia.
Archives of general psychiatry 1990;47(7):641-8.
1990: Schreiber J L; Breier A; Pickar D
Characteristics of patients selected for treatment on a schizophrenia research unit.
Hospital & community psychiatry 1990;41(4):441-3.
1990: Wolkowitz O M; Papadopoulos N M; Costello R; Breier A; Doran A R; Pickar D; Rubinow D
Prednisone effects on blood-brain barrier permeability and CNS IgG synthesis in healthy humans.
Psychoneuroendocrinology 1990;15(2):155-8.
1990: Breier A; Paul S M
The GABAA/benzodiazepine receptor: implications for the molecular basis of anxiety.
Journal of psychiatric research 1990;24 Suppl 2():91-104.
1990: Pickar D; Litman R E; Konicki P E; Wolkowitz O M; Breier A
Neurochemical and neural mechanisms of positive and negative symptoms in schizophrenia.
Modern problems of pharmacopsychiatry 1990;24():124-51.
1989: Breier A
A.E. Bennett award paper. Experimental approaches to human stress research: assessment of neurobiological mechanisms of stress in volunteers and psychiatric patients.
Biological psychiatry 1989;26(5):438-62.
1989: Wolkowitz O M; Doran A; Breier A; Roy A; Pickar D
Specificity of plasma HVA response to dexamethasone in psychotic depression.
Psychiatry research 1989;29(2):177-86.
1989: Wolkowitz O M; Breier A; Doran A; Lucas P; Kelsoe J; Paul S M; Pickar D
Alprazolam augmentation of neuroleptics in schizophrenia.
The American journal of psychiatry 1989;146(8):1087-8.
1989: Doran A R; Rubinow D R; Wolkowitz O M; Roy A; Breier A; Pickar D
Fluphenazine treatment reduces CSF somatostatin in patients with schizophrenia: correlations with CSF HVA.
Biological psychiatry 1989;25(4):431-9.
1988: Breier A; Kelsoe J R; Kirwin P D; Beller S A; Wolkowitz O M; Pickar D
Early parental loss and development of adult psychopathology.
Archives of general psychiatry 1988;45(11):987-93.
1988: Breier A; Wolkowitz O M; Doran A R; Bellar S; Pickar D
Neurobiological effects of lumbar puncture stress in psychiatric patients and healthy volunteers.
Psychiatry research 1988;25(2):187-94.
1988: Wolkowitz O M; Breier A; Doran A; Kelsoe J; Lucas P; Paul S M; Pickar D
Alprazolam augmentation of the antipsychotic effects of fluphenazine in schizophrenic patients. Preliminary results.
Archives of general psychiatry 1988;45(7):664-71.
1988: Breier A
Stress isn't always bad.
Hospital & community psychiatry 1988;39(6):591.
1988: Wolkowitz O M; Breier A; Doran A; Rubinow D; Berrettini W; Coppola R; Gold P; Pickar D
Prednisone-induced behavioral and biological changes in medically healthy volunteers.
Psychopharmacology bulletin 1988;24(3):492-4.
1988: Breier A
Small sample studies: unique contributions for large sample outcome studies.
Schizophrenia bulletin 1988;14(4):589-93.
1988: Pickar D; Breier A; Kelsoe J
Plasma homovanillic acid as an index of central dopaminergic activity: studies in schizophrenic patients.
Annals of the New York Academy of Sciences 1988;537():339-46.
1988: Breier A; Wolkowitz O M; Rapaport M; Paul S M; Pickar D
Metabolic stress effects in normal volunteers and schizophrenic patients.
Psychopharmacology bulletin 1988;24(3):431-3.
1987: Breier A; Wolkowitz O M; Doran A R; Roy A; Boronow J; Hommer D W; Pickar D
Neuroleptic responsivity of negative and positive symptoms in schizophrenia.
The American journal of psychiatry 1987;144(12):1549-55.
1987: Doran A R; Boronow J; Weinberger D R; Wolkowitz O M; Breier A; Pickar D
Structural brain pathology in schizophrenia revisited. Prefrontal cortex pathology is inversely correlated with cerebrospinal fluid levels of homovanillic acid.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1987;1(1):25-32.
1987: Breier A; Arora P K; Wolkowitz O M; Pickar D; Paul S M
Metabolic stress produces rapid immunosuppression in humans.
Archives of general psychiatry 1987;44(12):1108-9.
1987: Breier A; Albus M; Pickar D; Zahn T P; Wolkowitz O M; Paul S M
Controllable and uncontrollable stress in humans: alterations in mood and neuroendocrine and psychophysiological function.
The American journal of psychiatry 1987;144(11):1419-25.
1987: Wolkowitz O M; Rubinow D R; Breier A; Doran A R; Davis C; Pickar D
Prednisone decreases CSF somatostatin in healthy humans: implications for neuropsychiatric illness.
Life sciences 1987;41(16):1929-33.
1987: Wolkowitz O M; Doran A R; Breier A; Roy A; Jimerson D C; Sutton M E; Golden R N; Paul S M; Pickar D
The effects of dexamethasone on plasma homovanillic acid and 3-methoxy-4-hydroxyphenylglycol. Evidence for abnormal corticosteroid-catecholamine interactions in major depression.
Archives of general psychiatry 1987;44(9):782-9.
1987: Harding C M; Brooks G W; Ashikaga T; Strauss J S; Breier A
The Vermont longitudinal study of persons with severe mental illness, II: Long-term outcome of subjects who retrospectively met DSM-III criteria for schizophrenia.
The American journal of psychiatry 1987;144(6):727-35.
1987: Harding C M; Brooks G W; Ashikaga T; Strauss J S; Breier A
The Vermont longitudinal study of persons with severe mental illness, I: Methodology, study sample, and overall status 32 years later.
The American journal of psychiatry 1987;144(6):718-26.
1987: Pickar D; Wolkowitz O M; Doran A R; Labarca R; Roy A; Breier A; Narang P K
Clinical and biochemical effects of verapamil administration to schizophrenic patients.
Archives of general psychiatry 1987;44(2):113-8.
1987: Pickar D; Wolkowitz O M; Labarca R; Doran A R; Breier A; Paul S M
Biochemical alterations produced by neuroleptics in man: studies of plasma homovanillic acid in schizophrenic patients.
Psychopharmacology series 1987;3():248-54.
1986: Breier A; Charney D S; Heninger G R
Agoraphobia with panic attacks. Development, diagnostic stability, and course of illness.
Archives of general psychiatry 1986;43(11):1029-36.
1986: Breier A; Charney D S; Heninger G R
Intravenous diazepam fails to change growth hormone and cortisol secretion in humans.
Psychiatry research 1986;18(4):293-9.
1986: Pickar D; Labarca R; Doran A R; Wolkowitz O M; Roy A; Breier A; Linnoila M; Paul S M
Longitudinal measurement of plasma homovanillic acid levels in schizophrenic patients. Correlation with psychosis and response to neuroleptic treatment.
Archives of general psychiatry 1986;43(7):669-76.
1986: Wolkowitz O M; Doran A R; Breier A; Cohen M R; Pickar D
Endogenous opioid regulation of hypothalamo-pituitary-adrenal axis activity in schizophrenia.
Biological psychiatry 1986;21(4):366-73.
1986: Doran A R; Breier A; Roy A
Differential diagnosis and diagnostic systems in schizophrenia.
The Psychiatric clinics of North America 1986;9(1):17-33.
1986: Wolkowitz O M; Pickar D; Doran A R; Breier A; Tarell J; Paul S M
Combination alprazolam-neuroleptic treatment of the positive and negative symptoms of schizophrenia.
The American journal of psychiatry 1986;143(1):85-7.
1986: Charney D S; Heninger G R; Price L H; Breier A
Major depression and panic disorder: diagnostic and neurobiological relationships.
Psychopharmacology bulletin 1986;22(2):503-11.
1986: Charney D S; Breier A; Jatlow P I; Heninger G R
Behavioral, biochemical, and blood pressure responses to alprazolam in healthy subjects: interactions with yohimbine.
Psychopharmacology 1986;88(2):133-40.
1986: Pickar D; Roy A; Breier A; Doran A; Wolkowitz O; Colison J; Agren H
Suicide and aggression in schizophrenia. Neurobiologic correlates.
Annals of the New York Academy of Sciences 1986;487():189-96.
1985: Breier A; Charney D S; Heninger G R
The diagnostic validity of anxiety disorders and their relationship to depressive illness.
The American journal of psychiatry 1985;142(7):787-97.
1985: Doran A R; Narang P K; Meigs C Y; Wolkowitz O M; Roy A; Breier A; Pickar D
Verapamil concentrations in cerebrospinal fluid after oral administration.
The New England journal of medicine 1985;312(19):1261-2.
1984: Breier A; Charney D S; Heninger G R
Major depression in patients with agoraphobia and panic disorder.
Archives of general psychiatry 1984;41(12):1129-35.
1984: Breier A; Charney D S; Nelson J C
Seizures induced by abrupt discontinuation of alprazolam.
The American journal of psychiatry 1984;141(12):1606-7.
1984: Charney D S; Heninger G R; Breier A
Noradrenergic function in panic anxiety. Effects of yohimbine in healthy subjects and patients with agoraphobia and panic disorder.
Archives of general psychiatry 1984;41(8):751-63.
1984: Breier A; Strauss J S
The role of social relationships in the recovery from psychotic disorders.
The American journal of psychiatry 1984;141(8):949-55.
1984: Breier A; Ginsberg E M; Charney D S
Seminal emission induced by tricyclic antidepressant.
The American journal of psychiatry 1984;141(4):610-11.
1984: Breier A; Astrachan B M
Characterization of schizophrenic patients who commit suicide.
The American journal of psychiatry 1984;141(2):206-9.
1983: Breier A; Strauss J S
Self-control in psychotic disorders.
Archives of general psychiatry 1983;40(10):1141-5.
1981: Breier A; Hitzemann R J; Hirschowitz J; Garver D L
Kinetic analysis of platelet monoamine oxidase in chronic schizophrenia.
Life sciences 1981;28(17):1947-51.

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