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Yoshio Akagi

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Hidetaka Arishima; Makoto Isozaki; Hiroaki Takeuchi; Ken-ichirou Kikuta; Tatsuya Yamamoto; Hidemasa Uematsu; Hiroaki Kimura; Yoshihiro Takamura; Eri Kubo; Yoshio Akagi
[Optic nerve injury without optic canal fracture revealed by MR imaging with short inversion time inversion recovery sequences--a case report].
Eri Kubo; Nailia Hasanova; Yukie Tanaka; Nigar Fatma; Yoshihiro Takamura; Dhirendra P Singh; Yoshio Akagi
Protein expression profiling of lens epithelial cells from Prdx6-depleted mice and their vulnerability to UV radiation exposure.
Takeshi Tomomatsu; Yoshihiro Takamura; Eri Kubo; Yoshio Akagi
Aldose reductase inhibitor counteracts the attenuated adhesion of human corneal epithelial cells induced by high glucose through modulation of MMP-10 expression.

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All Publications

2010: Hidetaka Arishima; Makoto Isozaki; Hiroaki Takeuchi; Ken-ichirou Kikuta; Tatsuya Yamamoto; Hidemasa Uematsu; Hiroaki Kimura; Yoshihiro Takamura; Eri Kubo; Yoshio Akagi
[Optic nerve injury without optic canal fracture revealed by MR imaging with short inversion time inversion recovery sequences--a case report].
Brain and nerve = Shinkei kenkyū no shinpo 2010;62(8):898-900.
2010: Eri Kubo; Nailia Hasanova; Yukie Tanaka; Nigar Fatma; Yoshihiro Takamura; Dhirendra P Singh; Yoshio Akagi
Protein expression profiling of lens epithelial cells from Prdx6-depleted mice and their vulnerability to UV radiation exposure.
American journal of physiology. Cell physiology 2010;298(2):C342-54.
2009: Takeshi Tomomatsu; Yoshihiro Takamura; Eri Kubo; Yoshio Akagi
Aldose reductase inhibitor counteracts the attenuated adhesion of human corneal epithelial cells induced by high glucose through modulation of MMP-10 expression.
Diabetes research and clinical practice 2009;86(1):16-23.
2009: Eri Kubo; Kanako Kimura; Y Sugimoto; Yoshihiro Takamura; Yoshio Akagi
Bilateral optic disc macroaneurysm associated with acquired vascular loop.
Japanese journal of ophthalmology 2009;53(5):561-3.
2009: N Hasanova; Eri Kubo; Y Kumamoto; Yoshihiro Takamura; Yoshio Akagi
Age-related cataracts and Prdx6: correlation between severity of lens opacity, age and the level of Prdx 6 expression.
The British journal of ophthalmology 2009;93(8):1081-4.
2009: Eri Kubo; Dhirendra P Singh; Nigar Fatma; Yoshio Akagi
TAT-mediated peroxiredoxin 5 and 6 protein transduction protects against high-glucose-induced cytotoxicity in retinal pericytes.
Life sciences 2009;84(23-24):857-64.
2009: Yoshihiro Takamura; Eri Kubo; Yoshio Akagi
Analysis of the effect of intravitreal bevacizumab injection on diabetic macular edema after cataract surgery.
Ophthalmology 2009;116(6):1151-7.
2009: Hidetaka Arishiman; Makoto Isozaki; Yoshikazu Arai; Yuji Handa; Toshihiko Kubota; Yoshio Akagi
[Large optic nerve sheath meningioma].
Brain and nerve = Shinkei kenkyū no shinpo 2009;61(3):328-9.
2008: Hirotaka Nambu; Eri Kubo; Yoshihiro Takamura; Shosai Tsuzuki; Miyuki Tamura; Yoshio Akagi
Attenuation of aldose reductase gene suppresses high-glucose-induced apoptosis and oxidative stress in rat lens epithelial cells.
Diabetes research and clinical practice 2008;82(1):18-24.
2008: Yoshihiro Takamura; Takeshi Tomomatsu; Eri Kubo; Shousai Tsuzuki; Yoshio Akagi
Role of the polyol pathway in high glucose-induced apoptosis of retinal pericytes and proliferation of endothelial cells.
Investigative ophthalmology & visual science 2008;49(7):3216-23.
2008: Eri Kubo; Nigar Fatma; Yoshio Akagi; David Beier; Sanjay P Singh; Dhirendra P Singh
TAT-mediated PRDX6 protein transduction protects against eye lens epithelial cell death and delays lens opacity.
American journal of physiology. Cell physiology 2008;294(3):C842-55.
2007: Yuko Kumamoto; Yoshihiro Takamura; Eri Kubo; Shousai Tsuzuki; Yoshio Akagi
Epithelial cell density in cataractous lenses of patients with diabetes: association with erythrocyte aldose reductase.
Experimental eye research 2007;85(3):393-9.
2007: T Miyazawa; Eri Kubo; Yoshihiro Takamura; Yoshio Akagi
Up-regulation of P-glycoprotein expression by osmotic stress in rat sugar cataract.
Experimental eye research 2007;84(2):246-53.
2006: Eri Kubo; Y Kumamoto; Shousai Tsuzuki; Yoshio Akagi
Axial length, myopia, and the severity of lens opacity at the time of cataract surgery.
Archives of ophthalmology 2006;124(11):1586-90.
2006: Namiki Oishi; Soichi Morikubo; Yoshihiro Takamura; Eri Kubo; Shousai Tsuzuki; Tsuyoshi Tanimoto; Yoshio Akagi
Correlation between adult diabetic cataracts and red blood cell aldose reductase levels.
Investigative ophthalmology & visual science 2006;47(5):2061-4.
2006: Yuichi Okada; Takanobu Taniguchi; Shigeru Morishima; Fumiko Suzuki; Yoshio Akagi; Ikunobu Muramatsu
Characteristics of acid extrusion from Chinese hamster ovary cells expressing different prostaglandin EP receptors.
Life sciences 2006;78(21):2454-62.
2006: Jun Makita; Hisanori Kurooka; Kentaro Mori; Yoshio Akagi; Yoshifumi Yokota
Identification of the nuclear export signal in the helix-loop-helix inhibitor Id1.
FEBS letters 2006;580(7):1812-6.
2006: Eri Kubo; Tomoe Miyazawa; Nigar Fatma; Yoshio Akagi; Dhirendra P Singh
Development- and age-associated expression pattern of peroxiredoxin 6, and its regulation in murine ocular lens.
Mechanisms of ageing and development 2006;127(3):249-56.
2005: Yoshio Akagi; Eri Kubo
[Role of aldose reductase in the progression of diabetic retinopathies].
Nihon rinsho. Japanese journal of clinical medicine 2005;63 Suppl 6():194-201.
2005: Eri Kubo; D P Singh; Yoshio Akagi
Gene expression profiling of diabetic and galactosaemic cataractous rat lens by microarray analysis.
Diabetologia 2005;48(4):790-8.
2005: Hideshi Yagi; Yoshihiro Takamura; Toshiyuki Yoneda; Daijiro Konno; Yoshio Akagi; Kazunori Yoshida; Makoto Sato
Vlgr1 knockout mice show audiogenic seizure susceptibility.
Journal of neurochemistry 2005;92(1):191-202.
2004: Seiko Aoki; Yoshio Akagi; Wanchao Ma; Dayu Li; Abraham Spector
DeltaFosB expression and cataract.
Experimental eye research 2004;79(6):927-34.
2004: Nigar Fatma; Eri Kubo; Leo T Chylack; Toshimichi Shinohara; Yoshio Akagi; Dhirendra P Singh
LEDGF regulation of alcohol and aldehyde dehydrogenases in lens epithelial cells: stimulation of retinoic acid production and protection from ethanol toxicity.
American journal of physiology. Cell physiology 2004;287(2):C508-16.
2004: Soichi Morikubo; Yoshihiro Takamura; Eri Kubo; Shousai Tsuzuki; Yoshio Akagi
Corneal changes after small-incision cataract surgery in patients with diabetes mellitus.
Archives of ophthalmology 2004;122(7):966-9.
2004: Eri Kubo; T Urakami; Nigar Fatma; Yoshio Akagi; Dhirendra P Singh
Polyol pathway-dependent osmotic and oxidative stresses in aldose reductase-mediated apoptosis in human lens epithelial cells: role of AOP2.
Biochemical and biophysical research communications 2004;314(4):1050-6.
2003: Soichi Morikubo; Yoshihiro Takamura; Eri Kubo; Shousai Tsuzuki; Yoshio Akagi
[The inhibitory effect of aldose reductase inhibitor for proliferation in the lens epithelial cells of rat sugar cataract].
Nippon Ganka Gakkai zasshi 2003;107(10):565-70.
2003: Yoshihiro Takamura; Namiki Oishi; Eri Kubo; Shousai Tsuzuki; Yoshio Akagi
Morgagnian cataract with an isolated posterior capsular opening.
Archives of ophthalmology 2003;121(10):1487-8.
2003: Yoshihiro Takamura; Eri Kubo; Shousai Tsuzuki; Yoshio Akagi
Apoptotic cell death in the lens epithelium of rat sugar cataract.
Experimental eye research 2003;77(1):51-7.
2002: Namiki Oishi; Eri Kubo; Yoshihiro Takamura; K Maekawa; Tsuyoshi Tanimoto; Yoshio Akagi
Correlation between erythrocyte aldose reductase level and human diabetic retinopathy.
The British journal of ophthalmology 2002;86(12):1363-6.
2002: Yuichi Okada; Takanobu Taniguchi; Yoshio Akagi; Ikunobu Muramatsu
Two-phase response of acid extrusion triggered by purinoceptor in Chinese hamster ovary cells.
European journal of pharmacology 2002;455(1):19-25.
2002: Yoshihiro Takamura; Eri Kubo; Shousai Tsuzuki; Hideshi Yagi; Makoto Sato; Yoshio Akagi
Increased expression of p21(WAF-1/CIP-1) in the lens epithelium of rat sugar cataract.
Experimental eye research 2002;74(2):245-54.
2002: Fumiko Suzuki; Takanobu Taniguchi; Seigo Nakamura; Yoshio Akagi; Chikara Kubota; Makoto Satoh; Ikunobu Muramatsu
Distribution of alpha-1 adrenoceptor subtypes in RNA and protein in rabbit eyes.
British journal of pharmacology 2002;135(3):600-8.
2001: Yoshihiro Takamura; Y Sugimoto; Eri Kubo; Y Takahashi; Yoshio Akagi
Immunohistochemical study of apoptosis of lens epithelial cells in human and diabetic rat cataracts.
Japanese journal of ophthalmology 2001;45(6):559-63.
2001: M Tanaka; Y Okada; J Makita; Yoshihiro Takamura; Eri Kubo; R Kawai; Shousai Tsuzuki; Y Takahashi; Yoshio Akagi
Histologic examination of dislocated lenses.
Japanese journal of ophthalmology 2001;45(5):510-5.
2001: Eri Kubo; K Maekawa; Tsuyoshi Tanimoto; S Fujisawa; Yoshio Akagi
Biochemical and morphological changes during development of sugar cataract in Otsuka Long-Evans Tokushima fatty (OLETF) rat.
Experimental eye research 2001;73(3):375-81.
2001: Y Takamura; H Yagi; K Hase; Toshiyuki Yoneda; M Maeda; Yoshio Akagi; M Sato
JDD1, a novel member of the DnaJ family, is expressed in the germinal zone of the rat brain.
Biochemical and biophysical research communications 2001;285(2):387-92.
2000: Yoshihiro Takamura; Y Sugimoto; Eri Kubo; Y Takahashi; Yoshio Akagi
[Immunohistochemical study of apoptosis of lens epithelial cells in human and diabetic rat cataracts].
Nippon Ganka Gakkai zasshi 2000;104(4):221-5.
2000: Y Okada; S Nakamura; Eri Kubo; Namiki Oishi; Y Takahashi; Yoshio Akagi
Analysis of changes in corneal shape and refraction following scleral buckling surgery.
Japanese journal of ophthalmology 2000;44(2):132-8.
1999: Eri Kubo; S Nakamura; Shousai Tsuzuki; Y Takahashi; Yoshio Akagi; K Mizuno; A Matsubara
Inhibitory effect of orally administered aldose reductase inhibitor SNK-860 on corneal polyol accumulation in galactose-fed rats.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 1999;237(9):758-62.
1999: Seigo Nakamura; Takanobu Taniguchi; Fumiko Suzuki; Yoshio Akagi; Ikunobu Muramatsu
Evaluation of alpha1-adrenoceptors in the rabbit iris: pharmacological characterization and expression of mRNA.
British journal of pharmacology 1999;127(6):1367-74.
1999: Eri Kubo; N Miyoshi; M Fukuda; Yoshio Akagi
Cataract formation through the polyol pathway is associated with free radical production.
Experimental eye research 1999;68(4):457-64.
1998: Y Sugimoto; K Takayanagi; Shousai Tsuzuki; Y Takahashi; Yoshio Akagi
Postoperative changes over time in size of anterior capsulorrhexis in phacoemulsification/aspiration.
Japanese journal of ophthalmology 1998;42(6):495-8.
1998: S Aoki; Eri Kubo; S Nakamura; A Tsuzuki; Shousai Tsuzuki; Y Takahashi; Yoshio Akagi
Possible prognostic markers in conjunctival dysplasia and squamous cell carcinoma.
Japanese journal of ophthalmology 1998;42(4):256-61.
1998: T Kobayashi; Eri Kubo; Y Takahashi; T Kasahara; H Yonezawa; Yoshio Akagi
Retinal vessel changes in galactose-fed dogs.
Archives of ophthalmology 1998;116(6):785-9.
1998: Eri Kubo; K Mori; T Kobayashi; Y Takahashi; N Yokoi; S Kinoshita; T Kasahara; H Yonezawa; Yoshio Akagi
Effect of aldose reductase inhibitor on corneal epithelial barrier function in galactose-fed dogs.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 1998;14(2):181-90.
1997: Y Sugimoto; Eri Kubo; Shousai Tsuzuki; Y Takahashi; Yoshio Akagi
Histology of anterior capsule edges produced by CCC and DC.
Japanese journal of ophthalmology 1997;41(2):77-80.
1997: S Miyamoto; Takanobu Taniguchi; Fumiko Suzuki; M Takita; N Kosaka; Eiju Negoro; T Okuda; H Kosaka; S Murata; Seigo Nakamura; Yoshio Akagi; M Oshita; Y Watanabe; Ikunobu Muramatsu
Cloning, functional expression and tissue distribution of rabbit alpha1a-adrenoceptor.
Life sciences 1997;60(23):2069-74.
1996: Y Sugimoto; Eri Kubo; Shousai Tsuzuki; Y Takahashi; Yoshio Akagi
[Histological observation of anterior capsular edges produced by continuous curvilinear and diathermy capsulorhexis].
Nippon Ganka Gakkai zasshi 1996;100(11):858-62.
1995: K Takayanagi; Eri Kubo; Shousai Tsuzuki; T Kobayashi; K Mori; Y Takahashi; Yoshio Akagi
[Cell kinetics of rat lens epithelium by cytofluorometric nuclear DNA determination].
Nippon Ganka Gakkai zasshi 1995;99(10):1127-32.