Chi-Huey Wong

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Chuang Ming-Hong; Chiou Shyh-Horng; Huang Chun-Hao; Yang Wen-Bin; Wong Chi-Huey
The lifespan-promoting effect of acetic acid and Reishi polysaccharide.
Schiefner André; Fujio Masakazu; Wu Douglass; Wong Chi-Huey; Wilson Ian A
Structural evaluation of potent NKT cell agonists: implications for design of novel stimulatory ligands.
Wang Cheng-Chi; Chen Juine-Ruey; Tseng Yung-Chieh; Hsu Che-Hsiung; Hung Yu-Fu; Chen Shih-Wei; Chen Chin-Mei; Khoo Kay-Hooi; Cheng Ting-Jen; Cheng Yih-Shyun E; Jan Jia-Tsrong; Wu Chung-Yi; Ma Che; Wong Chi-Huey
Glycans on influenza hemagglutinin affect receptor binding and immune response.

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All Publications

2009: Chuang Ming-Hong; Chiou Shyh-Horng; Huang Chun-Hao; Yang Wen-Bin; Wong Chi-Huey
The lifespan-promoting effect of acetic acid and Reishi polysaccharide.
Bioorganic & medicinal chemistry 2009;17(22):7831-40.
2009: Schiefner André; Fujio Masakazu; Wu Douglass; Wong Chi-Huey; Wilson Ian A
Structural evaluation of potent NKT cell agonists: implications for design of novel stimulatory ligands.
Journal of molecular biology 2009;394(1):71-82.
2009: Wang Cheng-Chi; Chen Juine-Ruey; Tseng Yung-Chieh; Hsu Che-Hsiung; Hung Yu-Fu; Chen Shih-Wei; Chen Chin-Mei; Khoo Kay-Hooi; Cheng Ting-Jen; Cheng Yih-Shyun E; Jan Jia-Tsrong; Wu Chung-Yi; Ma Che; Wong Chi-Huey
Glycans on influenza hemagglutinin affect receptor binding and immune response.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(43):18137-42.
2009: Lewis Jared C; Bastian Sabine; Bennett Clay S; Fu Yu; Mitsuda Yuuichi; Chen Mike M; Greenberg William A; Wong Chi-Huey; Arnold Frances H
Chemoenzymatic elaboration of monosaccharides using engineered cytochrome P450BM3 demethylases.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(39):16550-5.
2009: Xu Ran; Hanson Sarah R; Zhang Zhiwen; Yang Yu-Ying; Schultz Peter G; Wong Chi-Huey
Site-specific incorporation of the mucin-type N-acetylgalactosamine-alpha-O-threonine into protein in Escherichia coli.
Journal of the American Chemical Society 2009;131(38):13883.
2009: Liang Chi-Hui; Wang Cheng-Chi; Lin Yu-Chen; Chen Chung-Hsuan; Wong Chi-Huey; Wu Chung-Yi
Iron oxide/gold core/shell nanoparticles for ultrasensitive detection of carbohydrate-protein interactions.
Analytical chemistry 2009;81(18):7750-6.
2009: Wen Wen-Hsien; Lin Mengi; Su Ching-Yao; Wang Shi-Yun; Cheng Yih-Shyun E; Fang Jim-Min; Wong Chi-Huey
Synergistic effect of zanamivir-porphyrin conjugates on inhibition of neuraminidase and inactivation of influenza virus.
Journal of medicinal chemistry 2009;52(15):4903-10.
2009: Motiei Leila; Rahimipour Shai; Thayer Desiree A; Wong Chi-Huey; Ghadiri M Reza
Antibacterial cyclic D,L-alpha-glycopeptides.
Chemical communications (Cambridge, England) 2009;(25):3693-5.
2009: Hong Zhangyong; Liu Lei; Sugiyama Masakazu; Fu Yu; Wong Chi-Huey
Concise synthesis of iminocyclitols via Petasis-type aminocyclization.
Journal of the American Chemical Society 2009;131(24):8352-3.
2009: Wu Chung-Yi; Liang Pi-Hui; Wong Chi-Huey
New development of glycan arrays.
Organic & biomolecular chemistry 2009;7(11):2247-54.
2009: Sung Ming-Ta; Lai Yen-Ting; Huang Chia-Ying; Chou Lien-Yang; Shih Hao-Wei; Cheng Wei-Chieh; Wong Chi-Huey; Ma Che
Crystal structure of the membrane-bound bifunctional transglycosylase PBP1b from Escherichia coli.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(22):8824-9.
2009: Wang Shi-Yun; Su Ching-Yao; Lin Mengi; Huang Shao-Yung; Huang Wen-I; Wang Cheng-Chi; Wu Ying-Ta; Cheng Ting-Jen R; Yu Hui-Ming; Ren Chien-Tai; Wu Chung-Yi; Wong Chi-Huey; Cheng Yih-Shyun E
HA-pseudotyped retroviral vectors for influenza antagonist screening.
Journal of biomolecular screening : the official journal of the Society for Biomolecular Screening 2009;14(3):294-302.
2009: Hanson Sarah R; Culyba Elizabeth K; Hsu Tsui-Ling; Wong Chi-Huey; Kelly Jeffery W; Powers Evan T
The core trisaccharide of an N-linked glycoprotein intrinsically accelerates folding and enhances stability.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(9):3131-6.
2008: Shi Chung-Sheng; Shi Guey-Yueh; Hsiao Shi-Ming; Kao Yuan-Chung; Kuo Kuan-Lin; Ma Chih-Yuan; Kuo Cheng-Hsiang; Chang Bi-Ing; Chang Chuan-Fa; Lin Chun-Hung; Wong Chi-Huey; Wu Hua-Lin
Lectin-like domain of thrombomodulin binds to its specific ligand Lewis Y antigen and neutralizes lipopolysaccharide-induced inflammatory response.
Blood 2008;112(9):3661-70.
2008: Giffin Michael J; Heaslet Holly; Brik Ashraf; Lin Ying-Chuan; Cauvi Gabrielle; Wong Chi-Huey; McRee Duncan E; Elder John H; Stout C David; Torbett Bruce E
A copper(I)-catalyzed 1,2,3-triazole azide-alkyne click compound is a potent inhibitor of a multidrug-resistant HIV-1 protease variant.
Journal of medicinal chemistry 2008;51(20):6263-70.
2008: Chen Ming-Wei; Cheng Ting-Jen Rachel; Huang Yaoxing; Jan Jia-Tsrong; Ma Shiou-Hwa; Yu Alice L; Wong Chi-Huey; Ho David D
A consensus-hemagglutinin-based DNA vaccine that protects mice against divergent H5N1 influenza viruses.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(36):13538-43.
2008: Liang Pi-Hui; Imamura Masakazu; Li Xiangming; Wu Douglass; Fujio Masakazu; Guy Richard T; Wu Bing-Ching; Tsuji Moriya; Wong Chi-Huey
Quantitative microarray analysis of intact glycolipid-CD1d interaction and correlation with cell-based cytokine production.
Journal of the American Chemical Society 2008;130(37):12348-54.
2008: Bennett Clay S; Dean Stephen M; Payne Richard J; Ficht Simon; Brik Ashraf; Wong Chi-Huey
Sugar-assisted glycopeptide ligation with complex oligosaccharides: scope and limitations.
Journal of the American Chemical Society 2008;130(36):11945-52.
2008: Tseng Susan Y; Wang Cheng-Chi; Lin Chin-Wei; Chen Cheng-Lung; Yu Wen-Yueh; Chen Chung-Hsuan; Wu Chung-Yi; Wong Chi-Huey
Glycan arrays on aluminum-coated glass slides.
Chemistry, an Asian journal 2008;3(8-9):1395-405.
2008: Su Ching-Yao; Wang Shi-Yun; Shie Jiun-Jie; Jeng King-Song; Temperton Nigel J; Fang Jim-Min; Wong Chi-Huey; Cheng Yih-Shyun E
In vitro evaluation of neuraminidase inhibitors using the neuraminidase-dependent release assay of hemagglutinin-pseudotyped viruses.
Antiviral research 2008;79(3):199-205.
2008: Wang Cheng-Chi; Huang Yen-Lin; Ren Chien-Tai; Lin Chin-Wei; Hung Jung-Tung; Yu Jyh-Cherng; Yu Alice L; Wu Chung-Yi; Wong Chi-Huey
Glycan microarray of Globo H and related structures for quantitative analysis of breast cancer.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(33):11661-6.
2008: Chang Wen-Wei; Lee Chien Hsin; Lee Peishan; Lin Juway; Hsu Chun-Wei; Hung Jung-Tung; Lin Jin-Jin; Yu Jyh-Cherng; Shao Li-en; Yu John; Wong Chi-Huey; Yu Alice L
Expression of Globo H and SSEA3 in breast cancer stem cells and the involvement of fucosyl transferases 1 and 2 in Globo H synthesis.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(33):11667-72.
2008: Kinjo Yuki; Pei Bo; Bufali Simone; Raju Ravinder; Richardson Stewart K; Imamura Masakazu; Fujio Masakazu; Wu Douglass; Khurana Archana; Kawahara Kazuyoshi; Wong Chi-Huey; Howell Amy R; Seeberger Peter H; Kronenberg Mitchell
Natural Sphingomonas glycolipids vary greatly in their ability to activate natural killer T cells.
Chemistry & biology 2008;15(7):654-64.
2008: Hsu Nien-Yeen; Tseng Susan Yu; Wu Chung-Yi; Ren Chien-Tai; Lee Yuan-Chang; Wong Chi-Huey; Chen Chung-Hsuan
Desorption ionization of biomolecules on metals.
Analytical chemistry 2008;80(13):5203-10.
2008: Astronomo Rena D; Lee Hing-Ken; Scanlan Christopher N; Pantophlet Ralph; Huang Cheng-Yuan; Wilson Ian A; Blixt Ola; Dwek Raymond A; Wong Chi-Huey; Burton Dennis R
A glycoconjugate antigen based on the recognition motif of a broadly neutralizing human immunodeficiency virus antibody, 2G12, is immunogenic but elicits antibodies unable to bind to the self glycans of gp120.
Journal of virology 2008;82(13):6359-68.
2008: Hsieh Yves S-Y; Chien Cheng; Liao Sylvian K-S; Liao Shih-Fen; Hung Wei-Ting; Yang Wen-Bin; Lin Chih-Chien; Cheng Ting-Jen Rachel; Chang Chia-Chuan; Fang Jim-Min; Wong Chi-Huey
Structure and bioactivity of the polysaccharides in medicinal plant Dendrobium huoshanense.
Bioorganic & medicinal chemistry 2008;16(11):6054-68.
2008: Chen Szu-Ting; Lin Yi-Ling; Huang Ming-Ting; Wu Ming-Fang; Cheng Shih-Chin; Lei Huan-Yao; Lee Chien-Kuo; Chiou Tzyy-Wen; Wong Chi-Huey; Hsieh Shie-Liang
CLEC5A is critical for dengue-virus-induced lethal disease.
Nature 2008;453(7195):672-6.
2008: Shao Yi-Ming; Yang Wen-Bin; Kuo Tun-Hsun; Tsai Keng-Chang; Lin Chun-Hung; Yang An-Suei; Liang Po-Huang; Wong Chi-Huey
Design, synthesis, and evaluation of trifluoromethyl ketones as inhibitors of SARS-CoV 3CL protease.
Bioorganic & medicinal chemistry 2008;16(8):4652-60.
2008: Northen Trent R; Lee Jinq-Chyi; Hoang Linh; Raymond Jason; Hwang Der-Ren; Yannone Steven M; Wong Chi-Huey; Siuzdak Gary
A nanostructure-initiator mass spectrometry-based enzyme activity assay.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(10):3678-83.
2008: Wang Sheng-Kai; Liang Pi-Hui; Astronomo Rena D; Hsu Tsui-Ling; Hsieh Shie-Liang; Burton Dennis R; Wong Chi-Huey
Targeting the carbohydrates on HIV-1: Interaction of oligomannose dendrons with human monoclonal antibody 2G12 and DC-SIGN.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(10):3690-5.
2008: Liang Pi-Hui; Wu Chung-Yi; Greenberg William A; Wong Chi-Huey
Glycan arrays: biological and medical applications.
Current opinion in chemical biology 2008;12(1):86-92.
2008: Wu Douglass; Fujio Masakazu; Wong Chi-Huey
Glycolipids as immunostimulating agents.
Bioorganic & medicinal chemistry 2008;16(3):1073-83.
2008: Cheng Ting-Jen Rachel; Sung Ming-Ta; Liao Hsin-Yu; Chang Yi-Fan; Chen Chia-Wei; Huang Chia-Ying; Chou Lien-Yang; Wu Yen-Da; Chen Yin-Hsuan; Cheng Yih-Shyun E; Wong Chi-Huey; Ma Che; Cheng Wei-Chieh
Domain requirement of moenomycin binding to bifunctional transglycosylases and development of high-throughput discovery of antibiotics.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(2):431-6.
2008: Chen Mu-Lin; Adak Avijit Kumar; Yeh Nai-Chia; Yang Wen-Bin; Chuang Yung-Jen; Wong Chi-Huey; Hwang Kuo-Chu; Hwu Jih-Ru Reuben; Hsieh Shih-Liang; Lin Chun-Cheng
Fabrication of an oriented Fc-fused lectin microarray through boronate formation.
Angewandte Chemie (International ed. in English) 2008;47(45):8627-30.
2008: Shie Jiun-Jie; Fang Jim-Min; Wong Chi-Huey
A concise and flexible synthesis of the potent anti-influenza agents tamiflu and tamiphosphor.
Angewandte Chemie (International ed. in English) 2008;47(31):5788-91.
2008: Payne Richard J; Ficht Simon; Greenberg William A; Wong Chi-Huey
Cysteine-free peptide and glycopeptide ligation by direct aminolysis.
Angewandte Chemie (International ed. in English) 2008;47(23):4411-5.
2008: Ficht Simon; Payne Richard J; Guy Richard T; Wong Chi-Huey
Solid-phase synthesis of peptide and glycopeptide thioesters through side-chain-anchoring strategies.
Chemistry (Weinheim an der Bergstrasse, Germany) 2008;14(12):3620-9.
2007: Sugiyama Masakazu; Hong Zhangyong; Liang Pi-Hui; Dean Stephen M; Whalen Lisa J; Greenberg William A; Wong Chi-Huey
D-Fructose-6-phosphate aldolase-catalyzed one-pot synthesis of iminocyclitols.
Journal of the American Chemical Society 2007;129(47):14811-7.
2007: Payne Richard J; Ficht Simon; Tang Sishi; Brik Ashraf; Yang Yu-Ying; Case David A; Wong Chi-Huey
Extended sugar-assisted glycopeptide ligations: development, scope, and applications.
Journal of the American Chemical Society 2007;129(44):13527-36.
2007: Polat Tülay; Wong Chi-Huey
Anomeric reactivity-based one-pot synthesis of heparin-like oligosaccharides.
Journal of the American Chemical Society 2007;129(42):12795-800.
2007: Shie Jiun-Jie; Fang Jim-Min; Wang Shi-Yun; Tsai Keng-Chang; Cheng Yih-Shyun E; Yang An-Suei; Hsiao Shih-Chia; Su Ching-Yao; Wong Chi-Huey
Synthesis of tamiflu and its phosphonate congeners possessing potent anti-influenza activity.
Journal of the American Chemical Society 2007;129(39):11892-3.
2007: Casey Charles P; Wong Chi-Huey
Partly cloudy with a chance of showers.
ACS chemical biology 2007;2(9):573-6.
2007: Shao Yi-Ming; Yang Wen-Bin; Peng Hung-Pin; Hsu Min-Feng; Tsai Keng-Chang; Kuo Tun-Hsun; Wang Andrew H-J; Liang Po-Huang; Lin Chun-Hung; Yang An-Suei; Wong Chi-Huey
Structure-based design and synthesis of highly potent SARS-CoV 3CL protease inhibitors.
Chembiochem : a European journal of chemical biology 2007;8(14):1654-7.
2007: Liang Pi-Hui; Wang Sheng-Kai; Wong Chi-Huey
Quantitative analysis of carbohydrate-protein interactions using glycan microarrays: determination of surface and solution dissociation constants.
Journal of the American Chemical Society 2007;129(36):11177-84.
2007: Sugiyama Masakazu; Hong Zhangyong; Greenberg William A; Wong Chi-Huey
In vivo selection for the directed evolution of L-rhamnulose aldolase from L-rhamnulose-1-phosphate aldolase (RhaD).
Bioorganic & medicinal chemistry 2007;15(17):5905-11.
2007: Wei Ming-Tzo; Hua Kuo-Feng; Hsu Jowey; Karmenyan Artashes; Tseng Kai-Yu; Wong Chi-Huey; Hsu Hsien-Yeh; Chiou Arthur
The interaction of lipopolysaccharide with membrane receptors on macrophages pretreated with extract of Reishi polysaccharides measured by optical tweezers.
Optics express 2007;15(17):11020-32.
2007: Kaltgrad Eiton; Sen Gupta Sayam; Punna Sreenivas; Huang Cheng-Yuan; Chang Aileen; Wong Chi-Huey; Finn M G; Blixt Ola
Anti-carbohydrate antibodies elicited by polyvalent display on a viral scaffold.
Chembiochem : a European journal of chemical biology 2007;8(12):1455-62.
2007: Bennett Clay S; Wong Chi-Huey
Chemoenzymatic approaches to glycoprotein synthesis.
Chemical Society reviews 2007;36(8):1227-38.
2007: Hua Kuo-Feng; Hsu Hsien-Yeh; Chao Louis Kuoping; Chen Shui-Tein; Yang Wen-Bin; Hsu Jason; Wong Chi-Huey
Ganoderma lucidum polysaccharides enhance CD14 endocytosis of LPS and promote TLR4 signal transduction of cytokine expression.
Journal of cellular physiology 2007;212(2):537-50.
2007: Chang Ya-Jen; Huang Jing-Rong; Tsai Yi-Chien; Hung Jung-Tung; Wu Douglass; Fujio Masakazu; Wong Chi-Huey; Yu Alice L
Potent immune-modulating and anticancer effects of NKT cell stimulatory glycolipids.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(25):10299-304.
2007: Yang Yu-Ying; Ficht Simon; Brik Ashraf; Wong Chi-Huey
Sugar-assisted ligation in glycoprotein synthesis.
Journal of the American Chemical Society 2007;129(24):7690-701.
2007: Hanson Sarah R; Hsu Tsui-Ling; Weerapana Eranthie; Kishikawa Kuniyuki; Simon Gabriel M; Cravatt Benjamin F; Wong Chi-Huey
Tailored glycoproteomics and glycan site mapping using saccharide-selective bioorthogonal probes.
Journal of the American Chemical Society 2007;129(23):7266-7.
2007: Michel Marie-Laure; Keller Alexandre Castro; Paget Christophe; Fujio Masakazu; Trottein François; Savage Paul B; Wong Chi-Huey; Schneider Elke; Dy Michel; Leite-de-Moraes Maria C
Identification of an IL-17-producing NK1.1(neg) iNKT cell population involved in airway neutrophilia.
The Journal of experimental medicine 2007;204(5):995-1001.
2007: Hsu Tsui-Ling; Hanson Sarah R; Kishikawa Kuniyuki; Wang Sheng-Kai; Sawa Masaaki; Wong Chi-Huey
Alkynyl sugar analogs for the labeling and visualization of glycoconjugates in cells.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(8):2614-9.
2007: Yu Zhanqian; Sawkar Anu R; Whalen Lisa J; Wong Chi-Huey; Kelly Jeffery W
Isofagomine- and 2,5-anhydro-2,5-imino-D-glucitol-based glucocerebrosidase pharmacological chaperones for Gaucher disease intervention.
Journal of medicinal chemistry 2007;50(1):94-100.
2007: Cheng Kun-Chieh; Huang Hsuan-Cheng; Chen Jenn-Han; Hsu Jia-Wei; Cheng Hsu-Chieh; Ou Chern-Han; Yang Wen-Bin; Chen Shui-Tein; Wong Chi-Huey; Juan Hsueh-Fen
Ganoderma lucidum polysaccharides in human monocytic leukemia cells: from gene expression to network construction.
BMC genomics 2007;8():411.
2007: Ficht Simon; Payne Richard J; Brik Ashraf; Wong Chi-Huey
Second-generation sugar-assisted ligation: a method for the synthesis of cysteine-containing glycopeptides.
Angewandte Chemie (International ed. in English) 2007;46(31):5975-9.
2007: Hsu Nien-Yeen; Yang Wen-Bin; Wong Chi-Huey; Lee Yuan-Chuan; Lee Reiko T; Wang Yi-Sheng; Chen Chung-Hsuan
Matrix-assisted laser desorption/ionization mass spectrometry of polysaccharides with 2',4',6'-trihydroxyacetophenone as matrix.
Rapid communications in mass spectrometry : RCM 2007;21(13):2137-46.
2007: Brik Ashraf; Wong Chi-Huey
Sugar-assisted ligation for the synthesis of glycopeptides.
Chemistry (Weinheim an der Bergstrasse, Germany) 2007;13(20):5670-5.
2006: Brik Ashraf; Ficht Simon; Wong Chi-Huey
Strategies for the preparation of homogenous glycoproteins.
Current opinion in chemical biology 2006;10(6):638-44.
2006: Hanson Sarah R; Whalen Lisa J; Wong Chi-Huey
Synthesis and evaluation of general mechanism-based inhibitors of sulfatases based on (difluoro)methyl phenyl sulfate and cyclic phenyl sulfamate motifs.
Bioorganic & medicinal chemistry 2006;14(24):8386-95.
2006: Brik Ashraf; Ficht Simon; Yang Yu-Ying; Bennett Clay S; Wong Chi-Huey
Sugar-assisted ligation of N-linked glycopeptides with broad sequence tolerance at the ligation junction.
Journal of the American Chemical Society 2006;128(46):15026-33.
2006: Hong Zhangyong; Liu Lei; Hsu Che-Chang; Wong Chi-Huey
Three-step synthesis of sialic acids and derivatives.
Angewandte Chemie (International ed. in English) 2006;45(44):7417-21.
2006: Liu Haitian; Wong Chi-Huey
Characterization of a transglycosylase domain of Streptococcus pneumoniae PBP1b.
Bioorganic & medicinal chemistry 2006;14(21):7187-95.
2006: Cheng Yih-Shyun E; Lo Kien-Hock; Hsu Hsien-Hua; Shao Yi-Ming; Yang Wen-Bin; Lin Chun-Hung; Wong Chi-Huey
Screening for HIV protease inhibitors by protection against activity-mediated cytotoxicity in Escherichia coli.
Journal of virological methods 2006;137(1):82-7.
2006: Thayer Desiree A; Wong Chi-Huey
Vancomycin analogues containing monosaccharides exhibit improved antibiotic activity: a combined one-pot enzymatic glycosylation and chemical diversification strategy.
Chemistry, an Asian journal 2006;1(3):445-52.
2006: Kinjo Yuki; Tupin Emmanuel; Wu Douglass; Fujio Masakazu; Garcia-Navarro Raquel; Benhnia Mohammed Rafii-El-Idrissi; Zajonc Dirk M; Ben-Menachem Gil; Ainge Gary D; Painter Gavin F; Khurana Archana; Hoebe Kasper; Behar Samuel M; Beutler Bruce; Wilson Ian A; Tsuji Moriya; Sellati Timothy J; Wong Chi-Huey; Kronenberg Mitchell
Natural killer T cells recognize diacylglycerol antigens from pathogenic bacteria.
Nature immunology 2006;7(9):978-86.
2006: Huang Kuo-Ting; Wu Bing-Ching; Lin Chang-Ching; Luo Shih-Chi; Chen Chinpan; Wong Chi-Huey; Lin Chun-Cheng
Multi-enzyme one-pot strategy for the synthesis of sialyl Lewis X-containing PSGL-1 glycopeptide.
Carbohydrate research 2006;341(12):2151-5.
2006: Sawa Masaaki; Hsu Tsui-Ling; Itoh Takeshi; Sugiyama Masakazu; Hanson Sarah R; Vogt Peter K; Wong Chi-Huey
Glycoproteomic probes for fluorescent imaging of fucosylated glycans in vivo.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(33):12371-6.
2006: Liang Fu-Sen; Greenberg William A; Hammond Jennifer A; Hoffmann Julia; Head Steven R; Wong Chi-Huey
Evaluation of RNA-binding specificity of aminoglycosides with DNA microarrays.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(33):12311-6.
2006: Lin Ying-Chuan; Brik Ashraf; de Parseval Aymeric; Tam Karen; Torbett Bruce E; Wong Chi-Huey; Elder John H
Altered gag polyprotein cleavage specificity of feline immunodeficiency virus/human immunodeficiency virus mutant proteases as demonstrated in a cell-based expression system.
Journal of virology 2006;80(16):7832-43.
2006: Sanna M Germana; Wang Sheng-Kai; Gonzalez-Cabrera Pedro J; Don Anthony; Marsolais David; Matheu Melanie P; Wei Sindy H; Parker Ian; Jo Euijung; Cheng Wei-Chieh; Cahalan Michael D; Wong Chi-Huey; Rosen Hugh
Enhancement of capillary leakage and restoration of lymphocyte egress by a chiral S1P1 antagonist in vivo.
Nature chemical biology 2006;2(8):434-41.
2006: Lin Kuo-I; Kao Yeong-Yi; Kuo Hui-Kai; Yang Wen-Bin; Chou Alice; Lin Hsin-Hung; Yu Alice L; Wong Chi-Huey
Reishi polysaccharides induce immunoglobulin production through the TLR4/TLR2-mediated induction of transcription factor Blimp-1.
The Journal of biological chemistry 2006;281(34):24111-23.
2006: Fujio Masakazu; Wu Douglass; Garcia-Navarro Raquel; Ho David D; Tsuji Moriya; Wong Chi-Huey
Structure-based discovery of glycolipids for CD1d-mediated NKT cell activation: tuning the adjuvant versus immunosuppression activity.
Journal of the American Chemical Society 2006;128(28):9022-3.
2006: Hsu Hsien-Yeh; Hua Kuo-Feng; Su Yu-Chang; Chu Li-Chieh; Su Shi-Chi; Chiu Huan-Wen; Wong Chi-Huey; Chen Shui-Tein; Shieh Chu-Wen; Yang Su-Sing; Chen Ya-Mai; Chao Louis Kuoping
Alkali-soluble polysaccharides of Rhizoclonium riparium alga induce IL-1 gene expression via protein kinase signaling pathways.
Journal of agricultural and food chemistry 2006;54(10):3558-65.
2006: Qiu Hong; Gabrielsen Anders; Agardh Hanna E; Wan Min; Wetterholm Anders; Wong Chi-Huey; Hedin Ulf; Swedenborg Jesper; Hansson Göran K; Samuelsson Bengt; Paulsson-Berne Gabrielle; Haeggström Jesper Z
Expression of 5-lipoxygenase and leukotriene A4 hydrolase in human atherosclerotic lesions correlates with symptoms of plaque instability.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(21):8161-6.
2006: Brik Ashraf; Yang Yu-Ying; Ficht Simon; Wong Chi-Huey
Sugar-assisted glycopeptide ligation.
Journal of the American Chemical Society 2006;128(17):5626-7.
2006: Brik Ashraf; Wu Chung-Yi; Wong Chi-Huey
Microtiter plate based chemistry and in situ screening: a useful approach for rapid inhibitor discovery.
Organic & biomolecular chemistry 2006;4(8):1446-57.
2006: Lee Jinq-Chyi; Wu Chung-Yi; Apon Junefredo V; Siuzdak Gary; Wong Chi-Huey
Reactivity-based one-pot synthesis of the tumor-associated antigen N3 minor octasaccharide for the development of a photocleavable DIOS-MS sugar array.
Angewandte Chemie (International ed. in English) 2006;45(17):2753-7.
2006: Wu Chung-Yi; King Ke-Yung; Kuo Chih-Jung; Fang Jim-Min; Wu Ying-Ta; Ho Ming-Yi; Liao Chung-Lin; Shie Jiun-Jie; Liang Po-Huang; Wong Chi-Huey
Stable benzotriazole esters as mechanism-based inactivators of the severe acute respiratory syndrome 3CL protease.
Chemistry & biology 2006;13(3):261-8.
2006: Wu Douglass; Zajonc Dirk M; Fujio Masakazu; Sullivan Barbara A; Kinjo Yuki; Kronenberg Mitchell; Wilson Ian A; Wong Chi-Huey
Design of natural killer T cell activators: structure and function of a microbial glycosphingolipid bound to mouse CD1d.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(11):3972-7.
2006: Brigl Manfred; van den Elzen Peter; Chen Xiuxu; Meyers Jennifer Hartt; Wu Douglass; Wong Chi-Huey; Reddington Faye; Illarianov Petr A; Besra Gurdyal S; Brenner Michael B; Gumperz Jenny E
Conserved and heterogeneous lipid antigen specificities of CD1d-restricted NKT cell receptors.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(6):3625-34.
2006: Liu Lei; Hong Zhang-Yong; Wong Chi-Huey
Convergent glycopeptide synthesis by traceless Staudinger ligation and enzymatic coupling.
Chembiochem : a European journal of chemical biology 2006;7(3):429-32.
2006: Chuang Ming-Hong; Wu Ming-Shiang; Lo Wan-Lin; Lin Jaw-Town; Wong Chi-Huey; Chiou Shyh-Horng
The antioxidant protein alkylhydroperoxide reductase of Helicobacter pylori switches from a peroxide reductase to a molecular chaperone function.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(8):2552-7.
2006: Liang Fu-Sen; Brik Ashraf; Lin Ying-Chuan; Elder John H; Wong Chi-Huey
Epoxide opening in water and screening in situ for rapid discovery of enzyme inhibitors in microtiter plates.
Bioorganic & medicinal chemistry 2006;14(4):1058-62.
2006: Liang Pi-Hui; Cheng Wei-Chieh; Lee Yi-Ling; Yu Han-Pang; Wu Ying-Ta; Lin Yi-Ling; Wong Chi-Huey
Novel five-membered iminocyclitol derivatives as selective and potent glycosidase inhibitors: new structures for antivirals and osteoarthritis.
Chembiochem : a European journal of chemical biology 2006;7(1):165-73.
2006: Huang Cheng-Yuan; Thayer Desiree A; Chang Aileen Y; Best Michael D; Hoffmann Julia; Head Steve; Wong Chi-Huey
Carbohydrate microarray for profiling the antibodies interacting with Globo H tumor antigen.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(1):15-20.
2006: Liu Lei; Bennett Clay S; Wong Chi-Huey
Advances in glycoprotein synthesis.
Chemical communications (Cambridge, England) 2006;(1):21-33.
2006: Lee Jinq-Chyi; Greenberg William A; Wong Chi-Huey
Programmable reactivity-based one-pot oligosaccharide synthesis.
Nature protocols 2006;1(6):3143-52.
2005: Zajonc Dirk M; Maricic Igor; Wu Douglass; Halder Ramesh; Roy Keshab; Wong Chi-Huey; Kumar Vipin; Wilson Ian A
Structural basis for CD1d presentation of a sulfatide derived from myelin and its implications for autoimmunity.
The Journal of experimental medicine 2005;202(11):1517-26.
2005: Wei Sindy H; Rosen Hugh; Matheu Melanie P; Sanna M Germana; Wang Sheng-Kai; Jo Euijung; Wong Chi-Huey; Parker Ian; Cahalan Michael D
Sphingosine 1-phosphate type 1 receptor agonism inhibits transendothelial migration of medullary T cells to lymphatic sinuses.
Nature immunology 2005;6(12):1228-35.
2005: Wu Chung-Yi; Brik Ashraf; Wang Sheng-Kai; Chen Yu-Hsien; Wong Chi-Huey
Tetrabutylammonium fluoride-mediated rapid alkylation reaction in microtiter plates for the discovery of enzyme inhibitors in situ.
Chembiochem : a European journal of chemical biology 2005;6(12):2176-80.
2005: Sawkar Anu R; Adamski-Werner Sara L; Cheng Wei-Chieh; Wong Chi-Huey; Beutler Ernest; Zimmer Klaus-Peter; Kelly Jeffery W
Gaucher disease-associated glucocerebrosidases show mutation-dependent chemical chaperoning profiles.
Chemistry & biology 2005;12(11):1235-44.
2005: Calarese Daniel A; Lee Hing-Ken; Huang Cheng-Yuan; Best Michael D; Astronomo Rena D; Stanfield Robyn L; Katinger Hermann; Burton Dennis R; Wong Chi-Huey; Wilson Ian A
Dissection of the carbohydrate specificity of the broadly neutralizing anti-HIV-1 antibody 2G12.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(38):13372-7.
2005: Shie Jiun-Jie; Fang Jim-Min; Kuo Tun-Hsun; Kuo Chih-Jung; Liang Po-Huang; Huang Hung-Jyun; Wu Yin-Ta; Jan Jia-Tsrong; Cheng Yih-Shyun E; Wong Chi-Huey
Inhibition of the severe acute respiratory syndrome 3CL protease by peptidomimetic alpha,beta-unsaturated esters.
Bioorganic & medicinal chemistry 2005;13(17):5240-52.
2005: Brik Ashraf; Wu Chung-Yi; Best Michael D; Wong Chi-Huey
Tetrabutylammonium fluoride-assisted rapid N9-alkylation on purine ring: application to combinatorial reactions in microtiter plates for the discovery of potent sulfotransferase inhibitors in situ.
Bioorganic & medicinal chemistry 2005;13(15):4622-6.
2005: Thayer Desiree A; Yu Henry N; Galan M Carmen; Wong Chi-Huey
A general strategy toward S-linked glycopeptides.
Angewandte Chemie (International ed. in English) 2005;44(29):4596-9.
2005: Brik Ashraf; Alexandratos Jerry; Lin Ying-Chuan; Elder John H; Olson Arthur J; Wlodawer Alexander; Goodsell David S; Wong Chi-Huey
1,2,3-triazole as a peptide surrogate in the rapid synthesis of HIV-1 protease inhibitors.
Chembiochem : a European journal of chemical biology 2005;6(7):1167-9.
2005: Shie Jiun-Jie; Fang Jim-Min; Kuo Chih-Jung; Kuo Tun-Hsun; Liang Po-Huang; Huang Hung-Jyun; Yang Wen-Bin; Lin Chun-Hung; Chen Jiun-Ling; Wu Yin-Ta; Wong Chi-Huey
Discovery of potent anilide inhibitors against the severe acute respiratory syndrome 3CL protease.
Journal of medicinal chemistry 2005;48(13):4469-73.
2005: Hsu Che-Chang; Hong Zhangyong; Wada Masaru; Franke Dirk; Wong Chi-Huey
Directed evolution of D-sialic acid aldolase to L-3-deoxy-manno-2-octulosonic acid (L-KDO) aldolase.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(26):9122-6.
2005: Numa Mehdi M D; Lee Lac V; Hsu Che-Chang; Bower Kristen E; Wong Chi-Huey
Identification of novel anthrax lethal factor inhibitors generated by combinatorial Pictet-Spengler reaction followed by screening in situ.
Chembiochem : a European journal of chemical biology 2005;6(6):1002-6.
2005: Wong Chi-Huey
Protein glycosylation: new challenges and opportunities.
The Journal of organic chemistry 2005;70(11):4219-25.
2005: Xing Guo-Wen; Wu Douglass; Poles Michael A; Horowitz Amir; Tsuji Moriya; Ho David D; Wong Chi-Huey
Synthesis and human NKT cell stimulating properties of 3-O-sulfo-alpha/beta-galactosylceramides.
Bioorganic & medicinal chemistry 2005;13(8):2907-16.
2005: Kinjo Yuki; Wu Douglass; Kim Gisen; Xing Guo-Wen; Poles Michael A; Ho David D; Tsuji Moriya; Kawahara Kazuyoshi; Wong Chi-Huey; Kronenberg Mitchell
Recognition of bacterial glycosphingolipids by natural killer T cells.
Nature 2005;434(7032):520-5.
2005: Sinchaikul Supachok; Pan Fu-Ming; Cheng Ching-Wen; Wong Chi-Huey; Fang Jim-Min; Tseng Min-Jen; Chen Shui-Tein
Protein microarray using alpha-amino acids as metal tags on chips.
Bioorganic & medicinal chemistry letters 2005;15(5):1413-6.
2005: Wu Douglass; Xing Guo-Wen; Poles Michael A; Horowitz Amir; Kinjo Yuki; Sullivan Barbara; Bodmer-Narkevitch Vera; Plettenburg Oliver; Kronenberg Mitchell; Tsuji Moriya; Ho David D; Wong Chi-Huey
Bacterial glycolipids and analogs as antigens for CD1d-restricted NKT cells.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(5):1351-6.
2005: Tolbert Thomas J; Franke Dirk; Wong Chi-Huey
A new strategy for glycoprotein synthesis: ligation of synthetic glycopeptides with truncated proteins expressed in E. coli as TEV protease cleavable fusion protein.
Bioorganic & medicinal chemistry 2005;13(3):909-15.
2005: Fridman Micha; Belakhov Valery; Lee Lac V; Liang Fu-Sen; Wong Chi-Huey; Baasov Timor
Dual effect of synthetic aminoglycosides: antibacterial activity against Bacillus anthracis and inhibition of anthrax lethal factor.
Angewandte Chemie (International ed. in English) 2005;44(3):447-52.
2005: Scanlan Chris; Calarese Daniel; Lee Hing-Ken; Blixt Ola; Wong Chi-Huey; Wilson Ian; Burton Dennis; Dwek Raymond; Rudd Pauline
Antibody recognition of a carbohydrate epitope: a template for HIV vaccine design.
Advances in experimental medicine and biology 2005;564():7-8.
2004: Lin Hening; Thayer Desiree A; Wong Chi-Huey; Walsh Christopher T
Macrolactamization of glycosylated peptide thioesters by the thioesterase domain of tyrocidine synthetase.
Chemistry & biology 2004;11(12):1635-42.
2004: Mocharla Vani P; Colasson Benoit; Lee Lac V; Röper Stefanie; Sharpless K Barry; Wong Chi-Huey; Kolb Hartmuth C
In situ click chemistry: enzyme-generated inhibitors of carbonic anhydrase II.
Angewandte Chemie (International ed. in English) 2004;44(1):116-20.
2004: Liang Fu-Sen; Wang Sheng-Kai; Nakatani Takuji; Wong Chi-Huey
Targeting RNAs with tobramycin analogues.
Angewandte Chemie (International ed. in English) 2004;43(47):6496-500.
2004: Nyffeler Paul T; Durón Sergio Gonzalez; Burkart Michael D; Vincent Stéphane P; Wong Chi-Huey
Selectfluor: mechanistic insight and applications.
Angewandte Chemie (International ed. in English) 2004;44(2):192-212.
2004: Chen Jenn-Han; Chang Yu-Wang; Yao Chen-Wen; Chiueh Tzong-Shi; Huang Su-Chin; Chien Ko-Yi; Chen An; Chang Feng-Yee; Wong Chi-Huey; Chen Yu-Ju
Plasma proteome of severe acute respiratory syndrome analyzed by two-dimensional gel electrophoresis and mass spectrometry.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(49):17039-44.
2004: Xu Ran; Hanson Sarah R; Zhang Zhiwen; Yang Yu-Ying; Schultz Peter G; Wong Chi-Huey
Site-specific incorporation of the mucin-type N-acetylgalactosamine-alpha-O-threonine into protein in Escherichia coli.
Journal of the American Chemical Society 2004;126(48):15654-5.
2004: Blixt Ola; Head Steve; Mondala Tony; Scanlan Christopher; Huflejt Margaret E; Alvarez Richard; Bryan Marian C; Fazio Fabio; Calarese Daniel; Stevens James; Razi Nahid; Stevens David J; Skehel John J; van Die Irma; Burton Dennis R; Wilson Ian A; Cummings Richard; Bovin Nicolai; Wong Chi-Huey; Paulson James C
Printed covalent glycan array for ligand profiling of diverse glycan binding proteins.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(49):17033-8.
2004: Hanson Sarah; Best Michael; Bryan Marian C; Wong Chi-Huey
Chemoenzymatic synthesis of oligosaccharides and glycoproteins.
Trends in biochemical sciences 2004;29(12):656-63.
2004: Hsu Hsien-Yeh; Hua Kuo-Feng; Lin Chun-Cheng; Lin Chun-Hung; Hsu Jason; Wong Chi-Huey
Extract of Reishi polysaccharides induces cytokine expression via TLR4-modulated protein kinase signaling pathways.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(10):5989-99.
2004: Hanson Sarah R; Best Michael D; Wong Chi-Huey
Sulfatases: structure, mechanism, biological activity, inhibition, and synthetic utility.
Angewandte Chemie (International ed. in English) 2004;43(43):5736-63.
2004: Chien Chichen Michael; Cheng Jing-Long; Chang Wen-Teish; Tien Ming-Hsun; Tsao Chien-Ming; Chang Yung-Han; Chang Hwan-You; Hsieh Jung-Feng; Wong Chi-Huey; Chen Shui-Tein
Polysaccharides of Ganoderma lucidum alter cell immunophenotypic expression and enhance CD56+ NK-cell cytotoxicity in cord blood.
Bioorganic & medicinal chemistry 2004;12(21):5603-9.
2004: Chen Hung-Sen; Tsai Yow-Fu; Lin Steven; Lin Chia-Ching; Khoo Kay-Hooi; Lin Chun-Hung; Wong Chi-Huey
Studies on the immuno-modulating and anti-tumor activities of Ganoderma lucidum (Reishi) polysaccharides.
Bioorganic & medicinal chemistry 2004;12(21):5595-601.
2004: Heine Andreas; Luz John G; Wong Chi-Huey; Wilson Ian A
Analysis of the class I aldolase binding site architecture based on the crystal structure of 2-deoxyribose-5-phosphate aldolase at 0.99A resolution.
Journal of molecular biology 2004;343(4):1019-34.
2004: Chang Chuan-Fa; Ho Chin-Wen; Wu Chung-Yi; Chao Tsrong-An; Wong Chi-Huey; Lin Chun-Hung
Discovery of picomolar slow tight-binding inhibitors of alpha-fucosidase.
Chemistry & biology 2004;11(9):1301-6.
2004: Liu Junjie; Numa Mehdi M D; Liu Haitian; Huang Shi-Jung; Sears Pamela; Shikhman Alexander R; Wong Chi-Huey
Synthesis and high-throughput screening of N-acetyl-beta-hexosaminidase inhibitor libraries targeting osteoarthritis.
The Journal of organic chemistry 2004;69(19):6273-83.
2004: Nyffeler Paul T; Boyle Nicholas A; Eltepu Laxman; Wong Chi-Huey; Eschenmoser Albert; Lerner Richard A; Wentworth Paul
Dihydrogen trioxide (HOOOH) is generated during the thermal reaction between hydrogen peroxide and ozone.
Angewandte Chemie (International ed. in English) 2004;43(35):4656-9.
2004: Chapman Eli; Best Michael D; Hanson Sarah R; Wong Chi-Huey
Sulfotransferases: structure, mechanism, biological activity, inhibition, and synthetic utility.
Angewandte Chemie (International ed. in English) 2004;43(27):3526-48.
2004: Bryan Marian C; Fazio Fabio; Lee Hing-Ken; Huang Cheng-Yuan; Chang Aileen; Best Michael D; Calarese Daniel A; Blixt Ola; Paulson James C; Burton Dennis; Wilson Ian A; Wong Chi-Huey
Covalent display of oligosaccharide arrays in microtiter plates.
Journal of the American Chemical Society 2004;126(28):8640-1.
2004: Wu Chung-Yi; Jan Jia-Tsrong; Ma Shiou-Hwa; Kuo Chih-Jung; Juan Hsueh-Fen; Cheng Yih-Shyun E; Hsu Hsien-Hua; Huang Hsuan-Cheng; Wu Douglass; Brik Ashraf; Liang Fu-Sen; Liu Rai-Shung; Fang Jim-Min; Chen Shui-Tein; Liang Po-Huang; Wong Chi-Huey
Small molecules targeting severe acute respiratory syndrome human coronavirus.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(27):10012-7.
2004: Cheng Ting-Jen; Brik Ashraf; Wong Chi-Huey; Kan Chen-Chen
Model system for high-throughput screening of novel human immunodeficiency virus protease inhibitors in Escherichia coli.
Antimicrobial agents and chemotherapy 2004;48(7):2437-47.
2004: Best Michael D; Brik Ashraf; Chapman Eli; Lee Lac V; Cheng Wei-Chieh; Wong Chi-Huey
Rapid discovery of potent sulfotransferase inhibitors by diversity-oriented reaction in microplates followed by in situ screening.
Chembiochem : a European journal of chemical biology 2004;5(6):811-9.
2004: Bryan Marian C; Lee Lac V; Wong Chi-Huey
High-throughput identification of fucosyltransferase inhibitors using carbohydrate microarrays.
Bioorganic & medicinal chemistry letters 2004;14(12):3185-8.
2004: Lee Lac V; Bower Kristen E; Liang Fu-Sen; Shi Jin; Wu Douglass; Sucheck Steven J; Vogt Peter K; Wong Chi-Huey
Inhibition of the proteolytic activity of anthrax lethal factor by aminoglycosides.
Journal of the American Chemical Society 2004;126(15):4774-5.
2004: Cheng Ching-Wen; Lin Kuo-Chin; Pan Fu-Ming; Sinchaikul Supachok; Wong Chi-Huey; Su Wei-Chih; Hsu Ching-Hsiang; Chen Shui-Tein
Facile synthesis of metal-chelating peptides on chip for protein array.
Bioorganic & medicinal chemistry letters 2004;14(8):1987-90.
2004: Agnelli Fabio; Sucheck Steven J; Marby Kenneth A; Rabuka David; Yao Su-Lan; Sears Pamela S; Liang Fu-Sen; Wong Chi-Huey
Dimeric aminoglycosides as antibiotics.
Angewandte Chemie (International ed. in English) 2004;43(12):1562-6.
2004: Durón Sergio G; Polat Tülay; Wong Chi-Huey
N-(phenylthio)-epsilon-caprolactam: a new promoter for the activation of thioglycosides.
Organic letters 2004;6(5):839-41.
2004: Yu Henry N; Furukawa Jun-ichi; Ikeda Tsuyoshi; Wong Chi-Huey
Novel efficient routes to heparin monosaccharides and disaccharides achieved via regio- and stereoselective glycosidation.
Organic letters 2004;6(5):723-6.
2004: Heck Marie-Pierre; Vincent Stéphane P; Murray Brion W; Bellamy François; Wong Chi-Huey; Mioskowski Charles
Cyclic amidine sugars as transition-state analogue inhibitors of glycosidases: potent competitive inhibitors of mannosidases.
Journal of the American Chemical Society 2004;126(7):1971-9.
2004: Lee Hing-Ken; Scanlan Christopher N; Huang Cheng-Yuan; Chang Aileen Y; Calarese Daniel A; Dwek Raymond A; Rudd Pauline M; Burton Dennis R; Wilson Ian A; Wong Chi-Huey
Reactivity-based one-pot synthesis of oligomannoses: defining antigens recognized by 2G12, a broadly neutralizing anti-HIV-1 antibody.
Angewandte Chemie (International ed. in English) 2004;43(8):1000-3.
2004: Chou Chien-Hung; Wu Chung-Shieh; Chen Ching-Hui; Lu Lung-Dai; Kulkarni Suvarn S; Wong Chi-Huey; Hung Shang-Cheng
Regioselective glycosylation of neamine core: a facile entry to kanamycin B related analogues.
Organic letters 2004;6(4):585-8.
2004: Zhang Zhiwen; Gildersleeve Jeff; Yang Yu-Ying; Xu Ran; Loo Joseph A; Uryu Sean; Wong Chi-Huey; Schultz Peter G
A new strategy for the synthesis of glycoproteins.
Science (New York, N.Y.) 2004;303(5656):371-3.
2004: Franke Dirk; Hsu Che-Chang; Wong Chi-Huey
Directed evolution of aldolases.
Methods in enzymology 2004;388():224-38.
2004: Tolbert Thomas J; Wong Chi-Huey
Subtilisin-catalyzed glycopeptide condensation.
Methods in molecular biology (Clifton, N.J.) 2004;283():267-79.
2004: Tolbert Thomas J; Wong Chi-Huey
Conjugation of glycopeptide thioesters to expressed protein fragments: semisynthesis of glycosylated interleukin-2.
Methods in molecular biology (Clifton, N.J.) 2004;283():255-66.
2004: Klostermeier Dagmar; Sears Pamela; Wong Chi-Huey; Millar David P; Williamson James R
A three-fluorophore FRET assay for high-throughput screening of small-molecule inhibitors of ribosome assembly.
Nucleic acids research 2004;32(9):2707-15.
2003: Brik Ashraf; Muldoon John; Lin Ying-Chuan; Elder John H; Goodsell David S; Olson Arthur J; Fokin Valery V; Sharpless K Bary; Wong Chi-Huey
Rapid diversity-oriented synthesis in microtiter plates for in situ screening of HIV protease inhibitors.
Chembiochem : a European journal of chemical biology 2003;4(11):1246-8.
2003: Feizi Ten; Fazio Fabio; Chai Wengang; Wong Chi Huey
Carbohydrate microarrays - a new set of technologies at the frontiers of glycomics.
Current opinion in structural biology 2003;13(5):637-45.
2003: Wu Chung-Yi; Chang Chuan-Fa; Chen Jenny Szu-Yu; Wong Chi-Huey; Lin Chun-Hung
Rapid diversity-oriented synthesis in microtiter plates for in situ screening: discovery of potent and selective alpha-fucosidase inhibitors.
Angewandte Chemie (International ed. in English) 2003;42(38):4661-4.
2003: Ritter Thomas K; Mong Kwok-Kong T; Liu Haitian; Nakatani Takuji; Wong Chi-Huey
A programmable one-pot oligosaccharide synthesis for diversifying the sugar domains of natural products: a case study of vancomycin.
Angewandte Chemie (International ed. in English) 2003;42(38):4657-60.
2003: Mong Tony K-K; Lee Lac V; Brown Jillian R; Esko Jeffrey D; Wong Chi-Huey
Synthesis of N-acetyllactosamine derivatives with variation in the aglycon moiety for the study of inhibition of sialyl Lewis x expression.
Chembiochem : a European journal of chemical biology 2003;4(9):835-40.
2003: Franke Dirk; Machajewski Timothy; Hsu Che-Chang; Wong Chi-Huey
One-pot synthesis of L-Fructose using coupled multienzyme systems based on rhamnulose-1-phosphate aldolase.
The Journal of organic chemistry 2003;68(17):6828-31.
2003: Lee Lac V; Mitchell Michael L; Huang Shih-Jung; Fokin Valery V; Sharpless K Barry; Wong Chi-Huey
A potent and highly selective inhibitor of human alpha-1,3-fucosyltransferase via click chemistry.
Journal of the American Chemical Society 2003;125(32):9588-9.
2003: Liu Haitian; Ritter Thomas K; Sadamoto Reiko; Sears Pamela S; Wu Min; Wong Chi-Huey
Acceptor specificity and inhibition of the bacterial cell-wall glycosyltransferase MurG.
Chembiochem : a European journal of chemical biology 2003;4(7):603-9.
2003: Wada Masaru; Hsu Che-Chang; Franke Dirk; Mitchell Michael; Heine Andreas; Wilson Ian; Wong Chi-Huey
Directed evolution of N-acetylneuraminic acid aldolase to catalyze enantiomeric aldol reactions.
Bioorganic & medicinal chemistry 2003;11(9):2091-8.
2003: Mak Chi Ching; Brik Ashraf; Lerner Danica L; Elder John H; Morris Garrett M; Olson Arthur J; Wong Chi-Huey
Design and synthesis of broad-based mono- and bi- cyclic inhibitors of FIV and HIV proteases.
Bioorganic & medicinal chemistry 2003;11(9):2025-40.
2003: Mong Tony K-K; Huang Cheng-Yuan; Wong Chi-Huey
A new reactivity-based one-pot synthesis of N-acetyllactosamine oligomers.
The Journal of organic chemistry 2003;68(6):2135-42.
2003: Liu Haitian; Wang Lei; Brock Ansgar; Wong Chi-Huey; Schultz Peter G
A method for the generation of glycoprotein mimetics.
Journal of the American Chemical Society 2003;125(7):1702-3.
2003: Mong Tony Kwok-Kong; Lee Hing-Ken; Duron Sergio G; Wong Chi-Huey
Reactivity-based one-pot total synthesis of fucose GM1 oligosaccharide: a sialylated antigenic epitope of small-cell lung cancer.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(3):797-802.
2003: Chapman Eli; Bryan Marian C; Wong Chi-Huey
Mechanistic studies of beta-arylsulfotransferase IV.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(3):910-5.
2003: Brik Ashraf; Wong Chi-Huey
HIV-1 protease: mechanism and drug discovery.
Organic & biomolecular chemistry 2003;1(1):5-14.
2003: DeSantis Grace; Liu Junjie; Clark David P; Heine Andreas; Wilson Ian A; Wong Chi-Huey
Structure-based mutagenesis approaches toward expanding the substrate specificity of D-2-deoxyribose-5-phosphate aldolase.
Bioorganic & medicinal chemistry 2003;11(1):43-52.
2003: Wong Chi-Huey; Liang Fu-Sen
Surface plasmon resonance study of RNA-aminoglycoside interactions.
Methods in enzymology 2003;362():340-53.
2003: Wong Chi-Huey; Bryan Marian C
Sugar arrays in microtiter plates.
Methods in enzymology 2003;362():218-25.
2002: Chapman Eli; Ding Sheng; Schultz Peter G; Wong Chi-Huey
A potent and highly selective sulfotransferase inhibitor.
Journal of the American Chemical Society 2002;124(49):14524-5.
2002: Fazio Fabio; Bryan Marian C; Blixt Ola; Paulson James C; Wong Chi-Huey
Synthesis of sugar arrays in microtiter plate.
Journal of the American Chemical Society 2002;124(48):14397-402.
2002: Sawkar Anu R; Cheng Wei-Chieh; Beutler Ernest; Wong Chi-Huey; Balch William E; Kelly Jeffery W
Chemical chaperones increase the cellular activity of N370S beta -glucosidase: a therapeutic strategy for Gaucher disease.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(24):15428-33.
2002: Mong Kwok-Kong T; Wong Chi-Huey
Reactivity-based one-pot synthesis of a Lewis Y carbohydrate hapten: a colon-rectal cancer antigen determinant.
Angewandte Chemie (International ed. in English) 2002;41(21):4087-90.
2002: Thunnissen Marjolein M G M; Andersson Björn; Samuelsson Bengt; Wong Chi-Huey; Haeggström Jesper Z
Crystal structures of leukotriene A4 hydrolase in complex with captopril and two competitive tight-binding inhibitors.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(12):1648-50.
2002: Nyffeler Paul T; Liang Chang-Hsing; Koeller Kathryn M; Wong Chi-Huey
The chemistry of amine-azide interconversion: catalytic diazotransfer and regioselective azide reduction.
Journal of the American Chemical Society 2002;124(36):10773-8.
2002: Brik Ashraf; Lin Ying-Chuan; Elder John; Wong Chi-Huey
A quick diversity-oriented amide-forming reaction to optimize P-subsite residues of HIV protease inhibitors.
Chemistry & biology 2002;9(8):891-6.
2002: Mitchell Michael L; Tian Feng; Lee Lac V; Wong Chi-Huey
Synthesis and evaluation of transition-state analogue inhibitors of alpha-1,3-fucosyltransferase.
Angewandte Chemie (International ed. in English) 2002;41(16):3041-4.
2002: Sadamoto Reiko; Niikura Kenichi; Sears Pamela S; Liu Haitian; Wong Chi-Huey; Suksomcheep Akarat; Tomita Fusao; Monde Kenji; Nishimura Shin-Ichiro
Cell-wall engineering of living bacteria.
Journal of the American Chemical Society 2002;124(31):9018-9.
2002: Tolbert Thomas J; Wong Chi-Huey
New methods for proteomic research: preparation of proteins with N-terminal cysteines for labeling and conjugation.
Angewandte Chemie (International ed. in English) 2002;41(12):2171-4.
2002: Bryan Marian C; Plettenburg Oliver; Sears Pamela; Rabuka David; Wacowich-Sgarbi Shirley; Wong Chi-Huey
Saccharide display on microtiter plates.
Chemistry & biology 2002;9(6):713-20.
2002: Plettenburg Oliver; Bodmer-Narkevitch Vera; Wong Chi-Huey
Synthesis of alpha-galactosyl ceramide, a potent immunostimulatory agent.
The Journal of organic chemistry 2002;67(13):4559-64.
2002: Liu Junjie; Wong Chi-Huey
Aldolase-catalyzed asymmetric synthesis of novel pyranose synthons as a new entry to heterocycles and epothilones.
Angewandte Chemie (International ed. in English) 2002;41(8):1404-7.
2002: Kanemitsu Takuya; Wong Chi-Huey; Kanie Osamu
Solid-phase synthesis of oligosaccharides and on-resin quantitative monitoring using gated decoupling (13)C NMR.
Journal of the American Chemical Society 2002;124(14):3591-9.
2002: Wang Yuan-Yuan; Khoo Kay-Hooi; Chen Shui-Tein; Lin Chun-Cheng; Wong Chi-Huey; Lin Chun-Hung
Studies on the immuno-modulating and antitumor activities of Ganoderma lucidum (Reishi) polysaccharides: functional and proteomic analyses of a fucose-containing glycoprotein fraction responsible for the activities.
Bioorganic & medicinal chemistry 2002;10(4):1057-62.
2002: Guo Chao-Tan; Sun Xue-Long; Kanie Osamu; Shortridge Kennedy Francis; Suzuki Takashi; Miyamoto Daisei; Hidari Kazuya I-P Jwa; Wong Chi-Huey; Suzuki Yasuo
An O-glycoside of sialic acid derivative that inhibits both hemagglutinin and sialidase activities of influenza viruses.
Glycobiology 2002;12(3):183-90.
2002: Chapman Eli; Wong Chi-Huey
A pH sensitive colorometric assay for the high-throughput screening of enzyme inhibitors and substrates: a case study using kinases.
Bioorganic & medicinal chemistry 2002;10(3):551-5.
2001: Izumi M; Shen G J; Wacowich-Sgarbi S; Nakatani T; Plettenburg O; Wong C H
Microbial glycosyltransferases for carbohydrate synthesis: alpha-2,3-sialyltransferase from Neisseria gonorrheae.
Journal of the American Chemical Society 2001;123(44):10909-18.
2001: Kozlov I A; Mao S; Xu Y; Huang X; Lee L; Sears P S; Gao C; Coyle A R; Janda K D; Wong C H
Synthesis of solid-supported mirror-image sugars: a novel method for selecting receptors for cellular-surface carbohydrates.
Chembiochem : a European journal of chemical biology 2001;2(10):741-6.
2001: Heine A; DeSantis G; Luz J G; Mitchell M; Wong C H; Wilson I A
Observation of covalent intermediates in an enzyme mechanism at atomic resolution.
Science (New York, N.Y.) 2001;294(5541):369-74.
2001: Liu H; Sadamoto R; Sears P S; Wong C H
An efficient chemoenzymatic strategy for the synthesis of wild-type and vancomycin-resistant bacterial cell-wall precursors: UDP-N-acetylmuramyl-peptides.
Journal of the American Chemical Society 2001;123(40):9916-7.
2001: Bühler B; Lin Y C; Morris G; Olson A J; Wong C H; Richman D D; Elder J H; Torbett B E
Viral evolution in response to the broad-based retroviral protease inhibitor TL-3.
Journal of virology 2001;75(19):9502-8.
2001: Liu J; Shikhman A R; Lotz M K; Wong C H
Hexosaminidase inhibitors as new drug candidates for the therapy of osteoarthritis.
Chemistry & biology 2001;8(7):701-11.
2001: Le V D; Mak C C; Lin Y C; Elder J H; Wong C H
Structure-activity studies of FIV and HIV protease inhibitors containing allophenylnorstatine.
Bioorganic & medicinal chemistry 2001;9(5):1185-95.
2001: Sears P; Wong C H
Toward automated synthesis of oligosaccharides and glycoproteins.
Science (New York, N.Y.) 2001;291(5512):2344-50.
2001: Silvestri M G; Wong C H
Opening of thiiranes: preparation of orthogonal protected 2-thioglyceraldehyde.
The Journal of organic chemistry 2001;66(3):910-4.
2001: Mak C C; Le V D; Lin Y C; Elder J H; Wong C H
Design, synthesis, and biological evaluation of HIV/FIV protease inhibitors incorporating a conformationally constrained macrocycle with a small P3' residue.
Bioorganic & medicinal chemistry letters 2001;11(2):219-22.
2001: Koeller K M; Wong C H
Enzymes for chemical synthesis.
Nature 2001;409(6817):232-40.
2000: Sucheck S J; Wong C H
RNA as a target for small molecules.
Current opinion in chemical biology 2000;4(6):678-86.
2000: Romero A; Wong C H
Chemo-enzymatic total synthesis of 3-epiaustraline, australine, and 7-epialexine.
The Journal of organic chemistry 2000;65(24):8264-8.
2000: Koeller K M; Wong C H
Complex carbohydrate synthesis tools for glycobiologists: enzyme-based approach and programmable one-pot strategies.
Glycobiology 2000;10(11):1157-69.
2000: Sheppard T L; Wong C H; Joyce G F
Nucleoglycoconjugates: design and synthesis of a new class of DNA-carbohydrate conjugates.
Angewandte Chemie (International ed. in English) 2000;39(20):3660-3.
2000: Düffels A; Green L G; Lenz R; Ley S V; Vincent S P; Wong C H
Chemoenzymatic synthesis of L-galactosylated dimeric sialyl Lewis X structures employing alpha-1,3-fucosyltransferase V.
Bioorganic & medicinal chemistry 2000;8(10):2519-25.
2000: Burkart M D; Izumi M; Chapman E; Lin C H; Wong C H
Regeneration of PAPS for the enzymatic synthesis of sulfated oligosaccharides.
The Journal of organic chemistry 2000;65(18):5565-74.
2000: Burkart M D; Vincent S P; Düffels A; Murray B W; Ley S V; Wong C H
Chemo-enzymatic synthesis of fluorinated sugar nucleotide: useful mechanistic probes for glycosyltransferases.
Bioorganic & medicinal chemistry 2000;8(8):1937-46.
2000: Koeller K M; Wong C H
Emerging themes in medicinal glycoscience.
Nature biotechnology 2000;18(8):835-41.
2000: Vincent S P; Schleyer A; Wong C H
Asymmetric Strecker synthesis of C-glycopeptide.
The Journal of organic chemistry 2000;65(14):4440-3.
2000: Takayanagi M; Flessner T; Wong C H
A strategy for the solution-phase parallel synthesis of N-(pyrrolidinylmethyl)hydroxamic acids.
The Journal of organic chemistry 2000;65(12):3811-5.
2000: Koeller K M; Smith M E; Wong C H
Chemoenzymatic synthesis of PSGL-1 glycopeptides: sulfation on tyrosine affects glycosyltransferase-catalyzed synthesis of the O-glycan.
Bioorganic & medicinal chemistry 2000;8(5):1017-25.
2000: Lin Y C; Beck Z; Lee T; Le V D; Morris G M; Olson A J; Wong C H; Elder J H
Alteration of substrate and inhibitor specificity of feline immunodeficiency virus protease.
Journal of virology 2000;74(10):4710-20.
2000: Ye X S; Wong C H
Anomeric reactivity-based one-pot oligosaccharide synthesis: a rapid route to oligosaccharide libraries.
The Journal of organic chemistry 2000;65(8):2410-31.
2000: Le V D; Wong C H
Synthesis of 2-substituted polyhydroxytetrahydropyrimidines (N-hydroxy cyclic guanidino-sugars): transition-state mimics of enzymatic glycosidic cleavage.
The Journal of organic chemistry 2000;65(8):2399-409.
2000: Koeller K M; Wong C H
Chemoenzymatic synthesis of sialyl-trimeric-Lewis x.
Chemistry (Weinheim an der Bergstrasse, Germany) 2000;6(7):1243-51.
2000: Wittmann V; Datta A K; Koeller K M; Wong C H
Chemoenzymatic synthesis and fluorescent visualization of cell-surface selectin-bound sialyl Lewis x derivatives.
Chemistry (Weinheim an der Bergstrasse, Germany) 2000;6(1):162-71.
1999: Shen G J; Datta A K; Izumi M; Koeller K M; Wong C H
Expression of alpha2,8/2,9-polysialyltransferase from Escherichia coli K92. Characterization of the enzyme and its reaction products.
The Journal of biological chemistry 1999;274(49):35139-46.
1999: Burkart M D; Wong C H
A continuous assay for the spectrophotometric analysis of sulfotransferases using aryl sulfotransferase IV.
Analytical biochemistry 1999;274(1):131-7.
1999: Weitz-Schmidt G; Gong K W; Wong C H
Selectin/glycoconjugate binding assays for the identification and optimization of selectin antagonists.
Analytical biochemistry 1999;273(1):81-8.
1999: Mao S; Gao C; Lo C H; Wirsching P; Wong C H; Janda K D
Phage-display library selection of high-affinity human single-chain antibodies to tumor-associated carbohydrate antigens sialyl Lewisx and Lewisx.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(12):6953-8.
1999: Huwe C M; Woltering T J; Jiricek J; Weitz-Schmidt G; Wong C H
Design, synthesis and biological evaluation of aryl-substituted sialyl Lewis X mimetics prepared via cross-metathesis of C-fucopeptides.
Bioorganic & medicinal chemistry 1999;7(5):773-88.
1999: Lin C C; Morís-Varas F; Weitz-Schmidt G; Wong C H
Synthesis of sialyl Lewis x mimetics as selectin inhibitors by enzymatic aldol condensation reactions.
Bioorganic & medicinal chemistry 1999;7(3):425-33.
1999: Takayama S; Chung S J; Igarashi Y; Ichikawa Y; Sepp A; Lechler R I; Wu J; Hayashi T; Siuzdak G; Wong C H
Selective inhibition of beta-1,4- and alpha-1,3-galactosyltransferases: donor sugar-nucleotide based approach.
Bioorganic & medicinal chemistry 1999;7(2):401-9.
1998: Chung S J; Takayama S; Wong C H
Acceptor substrate-based selective inhibition of galactosyltransferases.
Bioorganic & medicinal chemistry letters 1998;8(23):3359-64.
1998: Wischnat R; Martin R; Takayama S; Wong C H
Chemoenzymatic synthesis of iminocyclitol derivatives: a useful library strategy for the development of selective fucosyltransfer enzymes inhibitors.
Bioorganic & medicinal chemistry letters 1998;8(23):3353-8.
1998: Guo C T; Wong C H; Kajimoto T; Miura T; Ida Y; Juneja L R; Kim M J; Masuda H; Suzuki T; Suzuki Y
Synthetic sialylphosphatidylethanolamine derivatives bind to human influenza A viruses and inhibit viral infection.
Glycoconjugate journal 1998;15(11):1099-108.
1998: Tsai C Y; Park W K; Weitz-Schmidt G; Ernst B; Wong C H
Synthesis of sialyl Lewis X mimetics using the Ugi four-component reaction.
Bioorganic & medicinal chemistry letters 1998;8(17):2333-8.
1998: Martin R; Witte K L; Wong C H
The synthesis and enzymatic incorporation of sialic acid derivatives for use as tools to study the structure, activity, and inhibition of glycoproteins and other glycoconjugates.
Bioorganic & medicinal chemistry 1998;6(8):1283-92.
1998: Wong C H; Hendrix M; Priestley E S; Greenberg W A
Specificity of aminoglycoside antibiotics for the A-site of the decoding region of ribosomal RNA.
Chemistry & biology 1998;5(7):397-406.
1998: Sears P; Wong C H
Enzyme action in glycoprotein synthesis.
Cellular and molecular life sciences : CMLS 1998;54(3):223-52.
1998: Lee T; Laco G S; Torbett B E; Fox H S; Lerner D L; Elder J H; Wong C H
Analysis of the S3 and S3' subsite specificities of feline immunodeficiency virus (FIV) protease: development of a broad-based protease inhibitor efficacious against FIV, SIV, and HIV in vitro and ex vivo.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(3):939-44.
1997: Koketsu M; Nitoda T; Sugino H; Juneja L R; Kim M; Yamamoto T; Abe N; Kajimoto T; Wong C H
Synthesis of a novel sialic acid derivative (sialylphospholipid) as an antirotaviral agent.
Journal of medicinal chemistry 1997;40(21):3332-5.
1997: Wu J; Takayama S; Wong C H; Siuzdak G
Quantitative electrospray mass spectrometry for the rapid assay of enzyme inhibitors.
Chemistry & biology 1997;4(9):653-7.
1997: Hendrix M; Priestley E S; Joyce G F; Wong C H
Direct observation of aminoglycoside-RNA interactions by surface plasmon resonance.
Journal of the American Chemical Society 1997;119(16):3641-8.
1997: Wang R; Steensma D H; Takaoka Y; Yun J W; Kajimoto T; Wong C H
A search for pyrophosphate mimics for the development of substrates and inhibitors of glycosyltransferases.
Bioorganic & medicinal chemistry 1997;5(4):661-72.
1997: Hayashi T; Murray B W; Wang R; Wong C H
A chemoenzymatic synthesis of UDP-(2-deoxy-2-fluoro)-galactose and evaluation of its interaction with galactosyltransferase.
Bioorganic & medicinal chemistry 1997;5(3):497-500.
1997: Cappi M W; Moree W J; Qiao L; Marron T G; Weitz-Schmidt G; Wong C H
Synthesis of novel 6-amido-6-deoxy-l-galactose derivatives as sialyl Lewis X mimetics.
Bioorganic & medicinal chemistry 1997;5(2):283-96.
1997: Janda K D; Lo L C; Lo C H; Sim M M; Wang R; Wong C H; Lerner R A
Chemical selection for catalysis in combinatorial antibody libraries.
Science (New York, N.Y.) 1997;275(5302):945-8.
1997: Murray B W; Wittmann V; Burkart M D; Hung S C; Wong C H
Mechanism of human alpha-1,3-fucosyltransferase V: glycosidic cleavage occurs prior to nucleophilic attack.
Biochemistry 1997;36(4):823-31.
1997: Lin C H; Murray B W; Ollmann I R; Wong C H
Why is CMP-ketodeoxyoctonate highly unstable?
Biochemistry 1997;36(4):780-5.
1997: Takayama S; McGarvey G J; Wong C H
Microbial aldolases and transketolases: new biocatalytic approaches to simple and complex sugars.
Annual review of microbiology 1997;51():285-310.
1996: Qian X; Morís-Varas F; Fitzgerald M C; Wong C H
C2-symmetrical tetrahydroxyazepanes as inhibitors of glycosidases and HIV/FIV proteases.
Bioorganic & medicinal chemistry 1996;4(12):2055-69.
1996: Sears P; Wong C H
Intervention of carbohydrate recognition by proteins and nucleic acids.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(22):12086-93.
1996: Fitz W; Rosenthal P B; Wong C H
Synthesis and inhibitory properties of a thiomethylmercuric sialic acid with application to the X-ray structure determination of 9-O-acetylsialic acid esterase from influenza C virus.
Bioorganic & medicinal chemistry 1996;4(8):1349-53.
1996: Murray B W; Takayama S; Schultz J; Wong C H
Mechanism and specificity of human alpha-1,3-fucosyltransferase V.
Biochemistry 1996;35(34):11183-95.
1996: Uchiyama T; Woltering T J; Wong W; Lin C C; Kajimoto T; Takebayashi M; Weitz-Schmidt G; Asakura T; Noda M; Wong C H
Design and synthesis of C-linked fucosides as inhibitors of E-selectin.
Bioorganic & medicinal chemistry 1996;4(7):1149-65.
1996: De Luca C; Lansing M; Crescenzi F; Martini I; Shen G J; O'Regan M; Wong C H
Overexpression, one-step purification and characterization of UDP-glucose dehydrogenase and UDP-N-acetylglucosamine pyrophosphorylase.
Bioorganic & medicinal chemistry 1996;4(1):131-41.
1996: Hendrix M; Wong C H
A chemo-enzymatic approach to the study of carbohydrate recognition in biological systems.
Enantiomer 1996;1(4-6):305-10.
1995: Lin C H; Shimazaki M; Wong C H; Koketsu M; Juneja L R; Kim M
Enzymatic synthesis of a sialyl Lewis X dimer from egg yolk as an inhibitor of E-selectin.
Bioorganic & medicinal chemistry 1995;3(12):1625-30.
1995: Hogg J H; Ollmann I R; Haeggström J Z; Wetterholm A; Samuelsson B; Wong C H
Amino hydroxamic acids as potent inhibitors of leukotriene A4 hydrolase.
Bioorganic & medicinal chemistry 1995;3(10):1405-15.
1995: Garcia-Junceda E; Shen G J; Alajarin R; Wong C H
Cloning and overexpression of rhamnose isomerase and fucose isomerase.
Bioorganic & medicinal chemistry 1995;3(10):1349-55.
1995: Wetterholm A; Haeggström J Z; Samuelsson B; Yuan W; Munoz B; Wong C H
Potent and selective inhibitors of leukotriene A4 hydrolase: effects on purified enzyme and human polymorphonuclear leukocytes.
The Journal of pharmacology and experimental therapeutics 1995;275(1):31-7.
1995: Ollmann I R; Hogg J H; Muñoz B; Haeggström J Z; Samuelsson B; Wong C H
Investigation of the inhibition of leukotriene A4 hydrolase.
Bioorganic & medicinal chemistry 1995;3(7):969-95.
1995: Garcia-Junceda E; Shen G J; Sugai T; Wong C H
A new strategy for the cloning, overexpression and one step purification of three DHAP-dependent aldolases: rhamnulose-1-phosphate aldolase, fuculose-1-phosphate aldolase and tagatose-1,6-diphosphate aldolase.
Bioorganic & medicinal chemistry 1995;3(7):945-53.
1995: Stura E A; Ghosh S; Garcia-Junceda E; Chen L; Wong C H; Wilson I A
Crystallization and preliminary crystallographic data for class I deoxyribose-5-phosphate aldolase from Escherichia coli: an application of reverse screening.
Proteins 1995;22(1):67-72.
1995: Sugai T; Lin C H; Shen G J; Wong C H
CMP-KDO synthetase: overproduction and application to the synthesis of CMP-KDO and analogs.
Bioorganic & medicinal chemistry 1995;3(3):313-20.
1994: Provencher L; Steensma D H; Wong C H
Five-membered ring azasugars as potent inhibitors of alpha-L-rhamnosidase (naringinase) from Penicillium decumbens.
Bioorganic & medicinal chemistry 1994;2(11):1179-88.
1994: Munoz B; Giam C Z; Wong C H
Alpha-ketoamide Phe-Pro isostere as a new core structure for the inhibition of HIV protease.
Bioorganic & medicinal chemistry 1994;2(10):1085-90.
1994: Henderson I; Garcia-Junceda E; Liu K K; Chen Y L; Shen G J; Wong C H
Cloning, overexpression and isolation of the type II FDP aldolase from E. coli for specificity study and synthetic application.
Bioorganic & medicinal chemistry 1994;2(8):837-43.
1994: Aoki S; Kondo H; Wong C H
Glycosyl phosphites as glycosylation reagents.
Methods in enzymology 1994;247():193-211.
1994: Ichikawa Y; Wang R; Wong C H
Regeneration of sugar nucleotide for enzymatic oligosaccharide synthesis.
Methods in enzymology 1994;247():107-27.
1993: Yuan W; Munoz B; Wong C H; Haeggström J Z; Wetterholm A; Samuelsson B
Development of selective tight-binding inhibitors of leukotriene A4 hydrolase.
Journal of medicinal chemistry 1993;36(2):211-20.
1992: Wong C H; Liu K K; Kajimoto T; Chen L; Zhong Z; Ichikawa Y; Shen G J
Developing better enzymes for organic synthesis.
Annals of the New York Academy of Sciences 1992;672():343-51.
1992: Wong C H
Engineering enzymes for chemoenzymatic synthesis. Part 2: Modifying proteases for peptide synthesis.
Trends in biotechnology 1992;10(11):378-81.
1992: Wong C H
Engineering enzymes for chemoenzymatic synthesis. Part I: Practical routes to aza-sugars and complex carbohydrates.
Trends in biotechnology 1992;10(10):337-41.
1992: Ichikawa Y; Look G C; Wong C H
Enzyme-catalyzed oligosaccharide synthesis.
Analytical biochemistry 1992;202(2):215-38.
1991: Wong C H; Shen G J; Pederson R L; Wang Y F; Hennen W J
Enzymatic catalysis in organic synthesis.
Methods in enzymology 1991;202():591-620.

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