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Chi-Huey Wong

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TOP 3
Ting-Chun Hung; Chih-Wei Lin; Tsui-Ling Hsu; Chung-Yi Wu; Chi-Huey Wong
Investigation of SSEA-4 Binding Protein in Breast Cancer Cells.
Charng-Sheng Tsai; Tsung-I Tsai; Shi-Yun Wang; Yih-Shyun E Cheng; Jim-Min Fang; Tsui-Ling Sherry Hsu; Wen-I Huang; Meng-I Lin; Hsin-Yung Yen; Chi-Huey Wong
Cell-permeable probe for identification and imaging of sialidases.
Yen-Lin Huang; Jung-Tung Hung; Hsin-Yu Lee; Shiou-Ting Li; Yu-Chen Lin; Chien-Tai Ren; Ting-Jen R Cheng; Sarah K C Cheung; Kuo-Ching Chu; Tsui-Ling Sherry Hsu; Chung-Yi Wu; Alice L Yu; Chi-Huey Wong
Carbohydrate-based vaccines with a glycolipid adjuvant for breast cancer.

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2013: Ting-Chun Hung; Chih-Wei Lin; Tsui-Ling Hsu; Chung-Yi Wu; Chi-Huey Wong
Investigation of SSEA-4 Binding Protein in Breast Cancer Cells.
Journal of the American Chemical Society 2013;135(16):5934-7.
2013: Charng-Sheng Tsai; Tsung-I Tsai; Shi-Yun Wang; Yih-Shyun E Cheng; Jim-Min Fang; Tsui-Ling Sherry Hsu; Wen-I Huang; Meng-I Lin; Hsin-Yung Yen; Chi-Huey Wong
Cell-permeable probe for identification and imaging of sialidases.
Proceedings of the National Academy of Sciences of the United States of America 2013;110(7):2466-71.
2013: Yen-Lin Huang; Jung-Tung Hung; Hsin-Yu Lee; Shiou-Ting Li; Yu-Chen Lin; Chien-Tai Ren; Ting-Jen R Cheng; Sarah K C Cheung; Kuo-Ching Chu; Tsui-Ling Sherry Hsu; Chung-Yi Wu; Alice L Yu; Chi-Huey Wong
Carbohydrate-based vaccines with a glycolipid adjuvant for breast cancer.
Proceedings of the National Academy of Sciences of the United States of America 2013;110(7):2517-22.
2013: Katie J Doores; Colleen Doyle-Cooper; Michael Huber; Khoa M Le; David Nemazee; Ralph Pantophlet; Sheng-Kai Wang; Chi-Huey Wong; Anthony Cooper; Dennis R Burton
2G12-expressing B cell lines may aid in HIV carbohydrate vaccine design strategies.
Journal of virology 2013;87(4):2234-41.
2013: Esam Al-Shareffi; Jean-Luc Chaubard; Christina Leonhard-Melief; Sheng-Kai Wang; Chi-Huey Wong; Robert S Haltiwanger
6-alkynyl fucose is a bioorthogonal analog for O-fucosylation of epidermal growth factor-like repeats and thrombospondin type-1 repeats by protein O-fucosyltransferases 1 and 2.
Glycobiology 2013;23(2):188-98.
2013: Kuo-Ting Chen; Ting-Jen R Cheng; Wei-Chen Fu; Ye-Ching Kuan; Pi-Hui Liang; Chi-Huey Wong; Wei-Chieh Cheng
Rapid preparation of mycobacterium N-glycolyl Lipid I and Lipid II derivatives: a biocatalytic approach.
Chemistry (Weinheim an der Bergstrasse, Germany) 2013;19(3):834-8.
2013: Chien-Yu Chen; Michael Hsiao; Tsui-Ling Sherry Hsu; Ming-Shyan Huang; Yi-Hua Jan; Yi-Hsiu Juan; Chih-Jen Yang; Pan-Chyr Yang; Chong-Jen Yu; Chi-Huey Wong
Fucosyltransferase 8 as a functional regulator of nonsmall cell lung cancer.
Proceedings of the National Academy of Sciences of the United States of America 2013;110(2):630-5.
2013: Ting-Jen R Cheng; Yih-Shyun E Cheng; Jim-Min Fang; Wen-I Huang; Mengi Lin; Ming-Tsan Liu; Chien-Tai Ren; Ching-Yao Su; Nung-Sen Wang; Shi-Yun Wang; Wen-Hsien Wen; Chun-Lin Chen; Chung-Kai Cheng; Chung-Yi Wu; Ho-Sheng Wu; Chi-Huey Wong
Chemical probes for drug-resistance assessment by binding competition (RABC): oseltamivir susceptibility evaluation.
Angewandte Chemie (International ed. in English) 2013;52(1):366-70.
2012: Ting-Jen R Cheng; Yih-Shyun E Cheng; Jim-Min Fang; Wei-Che Hsieh; Oliver Yoa-Pu Hu; Pei-Wei Huang; Jia-Tsrong Jan; Wen-Hao Lin; Jiun-Jie Shie; E. Bart Tarbet; Shi-Yun Wang; Steven Weinheimer; Chih-An Chen; Chun-Lin Chen; Chi-Huey Wong
Development of oseltamivir phosphonate congeners as anti-influenza agents.
Journal of medicinal chemistry 2012;55(20):8657-70.
2012: Kung-Cheng Liu; Shi-Yun Wang; Shi-Ting Yang; Ting-Jen R Cheng; Yih-Shyun E Cheng; Jim-Min Fang; Jia-Tsrong Jan; Chi-Huey Wong
Enhanced anti-influenza agents conjugated with anti-inflammatory activity.
Journal of medicinal chemistry 2012;55(19):8493-501.
2012: Hao-Wei Shih; Chi-Huey Wong; Yi-Fan Chang; Ting-Jen R Cheng; Chia-Ying Huang; Wei-Jing Li; Che Ma; Fan-Chun Meng; Wei-Chieh Cheng
Effect of the peptide moiety of Lipid II on bacterial transglycosylase.
Angewandte Chemie (International ed. in English) 2012;51(40):10123-6.
2012: Ming-Han Hsieh; Jung-Tung Hung; Ya-Wen Liw; Yin-Jen Lu; Chi-Huey Wong; Alice L Yu; Pi-Hui Liang
Synthesis and evaluation of acyl-chain- and galactose-6''-modified analogues of α-GalCer for NKT cell activation.
Chembiochem : a European journal of chemical biology 2012;13(11):1689-97.
2012: Medel Manuel Zulueta; Susan D Arco; Chia-Lin Chyan; Yu-Peng Hu; Ching-Jui Huang; Deli Irene; Chiao-Chu Ku; Liang-Hin Lim; Shu-Yi Lin; Ya-Ting Lin; Zhonghao Shi; Tsung-I Tsai; Chun-Chih Wang; Chi-Huey Wong; Shang-Cheng Hung
α-Glycosylation by D-glucosamine-derived donors: synthesis of heparosan and heparin analogues that interact with mycobacterial heparin-binding hemagglutinin.
Journal of the American Chemical Society 2012;134(21):8988-95.
2012: Chia-Ying Huang; Li-Ying Lin; Ting-Jen Rachel Cheng; Wei-Chieh Cheng; Hao-Wei Shih; Yi-Wen Tien; Chi-Huey Wong; Che Ma
Crystal structure of Staphylococcus aureus transglycosylase in complex with a lipid II analog and elucidation of peptidoglycan synthesis mechanism.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(17):6496-501.
2012: Shan-He Chen; Ning-Shian Hsu; Der-Ren Hwang; Tsung-Lin Li; Gan-Hong Chen; Ying-Ta Wu; Chi-Huey Wong
Engineering transaldolase in Pichia stipitis to improve bioethanol production.
ACS chemical biology 2012;7(3):481-6.
2012: Yun Hsu; Shang-Cheng Hung; Kuo-I Lin; Xin-An Lu; Chih-Ming Tsai; Medel Manuel Zulueta; Chi-Huey Wong
Acyl and silyl group effects in reactivity-based one-pot glycosylation: synthesis of embryonic stem cell surface carbohydrates Lc4 and IV(2)Fuc-Lc4.
Journal of the American Chemical Society 2012;134(10):4549-52.
2012: Janina Lenger; Benjamin Müller; Thomas Noll; Marius Schröder; Thomas Dierks; Eva C Ennemann; Sarah R Hanson; Chi-Huey Wong; Norbert Sewald
Evaluation of sulfatase-directed quinone methide traps for proteomics.
Bioorganic & medicinal chemistry 2012;20(2):622-7.
2012: Joshua L Price; Chi-Huey Wong; Amber N Murray; Evan T Powers; Wentao Chen; Elizabeth K Culyba; Sarah R Hanson; Jeffery W Kelly
N-glycosylation of enhanced aromatic sequons to increase glycoprotein stability.
Biopolymers 2012;98(3):195-211.
2012: Matthijs R A Welkers; Chi-Huey Wong; Menno D De Jong; Jake Dunning; Frederick G Hayden
Current research on respiratory viral infections: XIIth International Symposium.
Antiviral therapy 2012;17(1 Pt B):227-53.
2011: Che-Hsiung Hsu; Shang-Cheng Hung; Chung-Yi Wu; Chi-Huey Wong
Toward automated oligosaccharide synthesis.
Angewandte Chemie (International ed. in English) 2011;50(50):11872-923.
2011: Jiun-Jie Shie; Keng-Chang Tsai; Shi-Yun Wang; Wen-Hsien Wen; Yih-Shyun E Cheng; Jim-Min Fang; Po-Ting Lai; An-Suei Yang; Chi-Huey Wong
A practical synthesis of zanamivir phosphonate congeners with potent anti-influenza activity.
Journal of the American Chemical Society 2011;133(44):17959-65.
2011: Tai-Na Wu; Alice L Yu; Ya-Jen Chang; Jing-Yan Cheng; Jing-Rong Huang; Kun-Hsien Lin; Chi-Huey Wong
Avidity of CD1d-ligand-receptor ternary complex contributes to T-helper 1 (Th1) polarization and anticancer efficacy.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(42):17275-80.
2011: Fan-Chun Meng; Fu-Yao Nien; Hao-Wei Shih; Chi-Huey Wong; Han-Hui Chang; Kuo-Ting Chen; Ting-Jen R Cheng; Lin-Ya Huang; Pi-Hui Liang; Wei-Chieh Cheng
Total synthesis of polyprenyl N-glycolyl lipid II as a mycobacterial transglycosylase substrate.
Organic letters 2011;13(19):5306-9.
2011: Yu-Fang Shen; Chi-Huey Wong; Chao-Jung Wu; Pei-Yu Wu; Ying-Ta Wu; An-Suei Yang; Yu-Hou Chen; Yih-Shyun E Cheng; Shao-Ying Chu; Hua-Ting Hsu; Pang-Hung Hsu; Fu-Yang Lin; Gialih Lin; Meng-I Lin; Hui-Wen Liu; Ming-Daw Tsai
E339...R416 salt bridge of nucleoprotein as a feasible target for influenza virus inhibitors.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(40):16515-20.
2011: Yuki Kinjo; Peter W Andrew; Gurdyal S Besra; Samira Dahesh; Enrico Girardi; Anaximandro Gómez-Velasco; Petr Illarionov; Masakazu Imamura; Yukihiro Kaneko; Kazuyoshi Kawahara; Kazuyoshi Kawakami; Archana Khurana; Xiangming Li; Yali Li; Yoshitsugu Miyazaki; Victor Nizet; Akiko Okawara; Bo Pei; Paul Rogers; Moriya Tsuji; Satoshi Uchiyama; José Luis Vela; Chi-Huey Wong; Hasan Yesilkaya; Dirk Zajonc; Mitchell Kronenberg
Invariant natural killer T cells recognize glycolipids from pathogenic Gram-positive bacteria.
Nature immunology 2011;12(10):966-74.
2011: Kuo-Ching Chu; Jeng-Liang Han; Che-Hsiung Hsu; Yung-Feng Lin; Chun-Ping Lu; Bikash Pal; Chien-Tai Ren; Tsung-Hsien Sun; Chi-Huey Wong; Tsung-An Chao; Shih-Hsiung Wu; Chung-Yi Wu
Efficient and stereoselective synthesis of α(2→9) oligosialic acids: from monomers to dodecamers.
Angewandte Chemie (International ed. in English) 2011;50(40):9391-5.
2011: Laura M Walker; Sheng-Kai Wang; Ian A Wilson; Chi-Huey Wong; Terri Wrin; Alejandra Ramos; Melissa D Simek; Dennis R Burton; Po-Ying Chan-Hui; Katie J Doores; Emilia Falkowska; Steven Fling; Phillip W Hammond; Michael Huber; Jean-Philippe Julien; Wayne C Koff; Jennifer L Mitcham; Matthew Moyle; Ole A Olsen; Robert Pejchal; Sanjay Phogat; Pham Phung; Pascal Poignard
Broad neutralization coverage of HIV by multiple highly potent antibodies.
Nature 2011;477(7365):466-70.
2011: Hao-Wei Shih; Chi-Huey Wong; Kuo-Ting Chen; Ting-Jen R Cheng; Wei-Chieh Cheng
A new synthetic approach toward bacterial transglycosylase substrates, Lipid II and Lipid IV.
Organic letters 2011;13(17):4600-3.
2011: Juine-Ruey Chen; Che Ma; Chi-Huey Wong
Vaccine design of hemagglutinin glycoprotein against influenza.
Trends in biotechnology 2011;29(9):426-34.
2011: Hui-Ling Yen; Kit M Yuen; Leo L M Poon; Richard J Webby; Robert G Webster; Chi-Huey Wong; Diana Dik-Yan Wong; Chung-Yi Wu; Michael C W Chan; Renee W Y Chan; Peter Pak-Hang Cheung; Ka-Tim Choy; Angela Ferguson; Heather L Forrest; Yi Guan; Che-Hsiung Hsu; Jeremy Jones; Scott Krauss; Olive T Li; Chi-Hui Liang; John M Nicholls; Malik Peiris
Hemagglutinin-neuraminidase balance confers respiratory-droplet transmissibility of the pandemic H1N1 influenza virus in ferrets.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(34):14264-9.
2011: Kung-Cheng Liu; Shi-Yun Wang; Yih-Shyun E Cheng; Jim-Min Fang; Pei-Shan Lee; Chi-Huey Wong
Intramolecular ion-pair prodrugs of zanamivir and guanidino-oseltamivir.
Bioorganic & medicinal chemistry 2011;19(16):4796-802.
2011: Ryan M Schmaltz; Sarah R Hanson; Chi-Huey Wong
Enzymes in the synthesis of glycoconjugates.
Chemical reviews 2011;111(7):4259-307.
2011: Ying-Chih Liu; Pan-Chyr Yang; Hsin-Yung Yen; Chong-Jen Yu; Chein-Hung Chen; Chung-Hsuan Chen; Chien-Yu Chen; Ping-Fu Cheng; Tsui-Ling Sherry Hsu; Yi-Hsiu Juan; Kay-Hooi Khoo; Chi-Huey Wong
Sialylation and fucosylation of epidermal growth factor receptor suppress its dimerization and activation in lung cancer cells.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(28):11332-7.
2011: Chuan Fa Chang; Chun-Nan Lin; Jia-Fu Pan; Chi-Huey Wong; I-Lin Wu; Chun-Hung Lin
Rapid characterization of sugar-binding specificity by in-solution proximity binding with photosensitizers.
Glycobiology 2011;21(7):895-902.
2011: Chung-Yi Wu; Chi-Huey Wong
Chemistry and glycobiology.
Chemical communications (Cambridge, England) 2011;47(22):6201-7.
2011: Chien-Yu Chou; Tzu-Ping Ko; Kuan-Jung Wu; Kai-Fa Huang; Chun-Hung Lin; Chi-Huey Wong; Andrew H-J Wang
Modulation of substrate specificities of D-sialic acid aldolase through single mutations of Val-251.
The Journal of biological chemistry 2011;286(16):14057-64.
2011: Reiko T Lee; Tsui-Ling Sherry Hsu; Shau-Ku Huang; Shie-Liang Hsieh; Chi-Huey Wong; Yuan C Lee
Survey of immune-related, mannose/fucose-binding C-type lectin receptors reveals widely divergent sugar-binding specificities.
Glycobiology 2011;21(4):512-20.
2011: Ming-Wei Chen; Hsin-Yu Liao; Yaoxing Huang; Jia-Tsrong Jan; Chih-Cheng Huang; Chien-Tai Ren; Chung-Yi Wu; Ting-Jen Rachel Cheng; David D Ho; Chi-Huey Wong
Broadly neutralizing DNA vaccine with specific mutation alters the antigenicity and sugar-binding activities of influenza hemagglutinin.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(9):3510-5.
2011: Chi-Hui Liang; Sheng-Kai Wang; Chin-Wei Lin; Cheng-Chi Wang; Chi-Huey Wong; Chung-Yi Wu
Effects of neighboring glycans on antibody-carbohydrate interaction.
Angewandte Chemie (International ed. in English) 2011;50(7):1608-12.
2011: Elizabeth K Culyba; Joshua L Price; Sarah R Hanson; Apratim Dhar; Chi-Huey Wong; Martin Gruebele; Evan T Powers; Jeffery W Kelly
Protein native-state stabilization by placing aromatic side chains in N-glycosylated reverse turns.
Science (New York, N.Y.) 2011;331(6017):571-5.
2011: Chung-Yi Wu; Chi-Huey Wong
Programmable one-pot glycosylation.
Topics in current chemistry 2011;301():223-52.
2011: Jia-Wei Hsu; Hsuan-Cheng Huang; Shui-Tein Chen; Chi-Huey Wong; Hsueh-Fen Juan
Ganoderma lucidum Polysaccharides Induce Macrophage-Like Differentiation in Human Leukemia THP-1 Cells via Caspase and p53 Activation.
Evidence-based complementary and alternative medicine : eCAM 2011;2011():358717.
2010: Ting-Jen Rachel Cheng; Ying-Ta Wu; Shih-Ting Yang; Kien-Hock Lo; Shao-Kang Chen; Yin-Hsuan Chen; Wen-I Huang; Chih-Hung Yuan; Chih-Wei Guo; Lin-Ya Huang; Kuo-Ting Chen; Hao-Wei Shih; Yih-Shyun E Cheng; Wei-Chieh Cheng; Chi-Huey Wong
High-throughput identification of antibacterials against methicillin-resistant Staphylococcus aureus (MRSA) and the transglycosylase.
Bioorganic & medicinal chemistry 2010;18(24):8512-29.
2010: Wan-Yu Chen; Wen-Bin Yang; Chi-Huey Wong; Daniel Tzu-bi Shih
Effect of Reishi polysaccharides on human stem/progenitor cells.
Bioorganic & medicinal chemistry 2010;18(24):8583-91.
2010: Jared C Lewis; Simone M Mantovani; Yu Fu; Christopher D Snow; Russell S Komor; Chi-Huey Wong; Frances H Arnold
Combinatorial alanine substitution enables rapid optimization of cytochrome P450BM3 for selective hydroxylation of large substrates.
Chembiochem : a European journal of chemical biology 2010;11(18):2502-5.
2010: Mathias Schelwies; Diana Brinson; Shuhei Otsuki; Young-Hoon Hong; Martin K Lotz; Chi-Huey Wong; Sarah R Hanson
Glucosamine-6-sulfamate analogues of heparan sulfate as inhibitors of endosulfatases.
Chembiochem : a European journal of chemical biology 2010;11(17):2393-7.
2010: Ching-Yao Su; Ting-Jen R Cheng; Meng-I Lin; Shi-Yun Wang; Wen-I Huang; Shao-Ying Lin-Chu; Yu-Hou Chen; Chung-Yi Wu; Michael M C Lai; Wei-Chieh Cheng; Ying-Ta Wu; Ming-Daw Tsai; Yih-Shyun E Cheng; Chi-Huey Wong
High-throughput identification of compounds targeting influenza RNA-dependent RNA polymerase activity.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(45):19151-6.
2010: Hsin-Yu Liao; Che-Hsiung Hsu; Shih-Chi Wang; Chi-Hui Liang; Hsin-Yung Yen; Ching-Yao Su; Chien-Hung Chen; Jia-Tsrong Jan; Chien-Tai Ren; Chung-Hsuan Chen; Ting-Jen R Cheng; Chung-Yi Wu; Chi-Huey Wong
Differential receptor binding affinities of influenza hemagglutinins on glycan arrays.
Journal of the American Chemical Society 2010;132(42):14849-56.
2010: Jiun-Jie Shie; Chih-An Chen; Chih-Chien Lin; Angela Fay Ku; Ting-Jen R Cheng; Jim-Min Fang; Chi-Huey Wong
Regioselective synthesis of di-C-glycosylflavones possessing anti-inflammation activities.
Organic & biomolecular chemistry 2010;8(19):4451-62.
2010: Kun-Hsien Lin; Jian-Jong Liang; Wen-I Huang; Shao-Ying Lin-Chu; Ching-Yao Su; Yi-Ling Lee; Jia-Tsong Jan; Yi-Ling Lin; Yih-Shyun E Cheng; Chi-Huey Wong
In vivo protection provided by a synthetic new alpha-galactosyl ceramide analog against bacterial and viral infections in murine models.
Antimicrobial agents and chemotherapy 2010;54(10):4129-36.
2010: Shih-Huang Chang; Jeng-Liang Han; Susan Y Tseng; Hsin-Yu Lee; Chin-Wei Lin; Yu-Chen Lin; Wen-Yih Jeng; Andrew H-J Wang; Chung-Yi Wu; Chi-Huey Wong
Glycan array on aluminum oxide-coated glass slides through phosphonate chemistry.
Journal of the American Chemical Society 2010;132(38):13371-80.
2010: Charng-Sheng Tsai; Po-Yu Liu; Hsin-Yung Yen; Tsui-Ling Sherry Hsu; Chi-Huey Wong
Development of trifunctional probes for glycoproteomic analysis.
Chemical communications (Cambridge, England) 2010;46(30):5575-7.
2010: Xiangming Li; Masakazu Fujio; Masakazu Imamura; Douglass Wu; Sandhya Vasan; Chi-Huey Wong; David D Ho; Moriya Tsuji
Design of a potent CD1d-binding NKT cell ligand as a vaccine adjuvant.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(29):13010-5.
2010: Hao-Wei Shih; Kuo-Ting Chen; Shao-Kang Chen; Chia-Ying Huang; Ting-Jen R Cheng; Che Ma; Chi-Huey Wong; Wei-Chieh Cheng
Combinatorial approach toward synthesis of small molecule libraries as bacterial transglycosylase inhibitors.
Organic & biomolecular chemistry 2010;8(11):2586-93.
2010: Shuhei Otsuki; Sarah R Hanson; Shigeru Miyaki; Shawn P Grogan; Mitsuo Kinoshita; Hiroshi Asahara; Chi-Huey Wong; Martin K Lotz
Extracellular sulfatases support cartilage homeostasis by regulating BMP and FGF signaling pathways.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(22):10202-7.
2010: Wen-Hsien Wen; Shi-Yun Wang; Keng-Chang Tsai; Yih-Shyun E Cheng; An-Suei Yang; Jim-Min Fang; Chi-Huey Wong
Analogs of zanamivir with modified C4-substituents as the inhibitors against the group-1 neuraminidases of influenza viruses.
Bioorganic & medicinal chemistry 2010;18(11):4074-84.
2010: Rena D Astronomo; Eiton Kaltgrad; Andrew K Udit; Sheng-Kai Wang; Katie J Doores; Cheng-Yuan Huang; Ralph Pantophlet; James C Paulson; Chi-Huey Wong; MG Finn; Dennis R Burton
Defining criteria for oligomannose immunogens for HIV using icosahedral virus capsid scaffolds.
Chemistry & biology 2010;17(4):357-70.
2010: Chen-Yu Liu; Chih-Wei Guo; Yi-Fan Chang; Jen-Tsung Wang; Hao-Wei Shih; Yu-Fang Hsu; Chia-Wei Chen; Shao-Kang Chen; Yen-Chih Wang; Ting-Jen R Cheng; Che Ma; Chi-Huey Wong; Jim-Min Fang; Wei-Chieh Cheng
Synthesis and evaluation of a new fluorescent transglycosylase substrate: lipid II-based molecule possessing a dansyl-C20 polyprenyl moiety.
Organic letters 2010;12(7):1608-11.
2010: Chia-Chuan Chang; Angela Fay Ku; Yun-Yu Tseng; Wen-Bin Yang; Jim-Min Fang; Chi-Huey Wong
6,8-Di-C-glycosyl flavonoids from Dendrobium huoshanense.
Journal of natural products 2010;73(2):229-32.
2010: Che-Hsiung Hsu; Kuo-Ching Chu; Yih-Shyan Lin; Jeng-Liang Han; Yu-Shiang Peng; Chien-Tai Ren; Chung-Yi Wu; Chi-Huey Wong
Highly alpha-selective sialyl phosphate donors for efficient preparation of natural sialosides.
Chemistry (Weinheim an der Bergstrasse, Germany) 2010;16(6):1754-60.
2010: Richard J Payne; Chi-Huey Wong
Advances in chemical ligation strategies for the synthesis of glycopeptides and glycoproteins.
Chemical communications (Cambridge, England) 2010;46(1):21-43.
2009: Tsui-Ling Sherry Hsu; Shih-Chin James Cheng; Wen-Bin Yang; See-Wen Chin; Bo-Hua Chen; Ming-Ting Huang; Shie-Liang Hsieh; Chi-Huey Wong
Profiling carbohydrate-receptor interaction with recombinant innate immunity receptor-Fc fusion proteins.
The Journal of biological chemistry 2009;284(50):34479-89.
2009: Zhiwen Zhang; Jeff Gildersleeve; Yu-Ying Yang; Ran Xu; Joseph A Loo; Sean Uryu; Chi-Huey Wong; Peter G Schultz
Retraction.
Science (New York, N.Y.) 2009;326(5957):1187.
2009: André Schiefner; Masakazu Fujio; Douglass Wu; Chi-Huey Wong; Ian A Wilson
Structural evaluation of potent NKT cell agonists: implications for design of novel stimulatory ligands.
Journal of molecular biology 2009;394(1):71-82.
2009: Ming-Hong Chuang; Shyh-Horng Chiou; Chun-Hao Huang; Wen-Bin Yang; Chi-Huey Wong
The lifespan-promoting effect of acetic acid and Reishi polysaccharide.
Bioorganic & medicinal chemistry 2009;17(22):7831-40.
2009: Cheng-Chi Wang; Juine-Ruey Chen; Yung-Chieh Tseng; Che-Hsiung Hsu; Yu-Fu Hung; Shih-Wei Chen; Chin-Mei Chen; Kay-Hooi Khoo; Ting-Jen Cheng; Yih-Shyun E Cheng; Jia-Tsrong Jan; Chung-Yi Wu; Che Ma; Chi-Huey Wong
Glycans on influenza hemagglutinin affect receptor binding and immune response.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(43):18137-42.
2009: Ran Xu; Sarah R Hanson; Zhiwen Zhang; Yu-Ying Yang; Peter G Schultz; Chi-Huey Wong
Site-specific incorporation of the mucin-type N-acetylgalactosamine-alpha-O-threonine into protein in Escherichia coli.
Journal of the American Chemical Society 2009;131(38):13883.
2009: Jared C Lewis; Sabine Bastian; Clay S Bennett; Yu Fu; Yuuichi Mitsuda; Mike M Chen; William A Greenberg; Chi-Huey Wong; Frances H Arnold
Chemoenzymatic elaboration of monosaccharides using engineered cytochrome P450BM3 demethylases.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(39):16550-5.
2009: Chi-Hui Liang; Cheng-Chi Wang; Yu-Chen Lin; Chung-Hsuan Chen; Chi-Huey Wong; Chung-Yi Wu
Iron oxide/gold core/shell nanoparticles for ultrasensitive detection of carbohydrate-protein interactions.
Analytical chemistry 2009;81(18):7750-6.
2009: Wen-Hsien Wen; Mengi Lin; Ching-Yao Su; Shi-Yun Wang; Yih-Shyun E Cheng; Jim-Min Fang; Chi-Huey Wong
Synergistic effect of zanamivir-porphyrin conjugates on inhibition of neuraminidase and inactivation of influenza virus.
Journal of medicinal chemistry 2009;52(15):4903-10.
2009: Leila Motiei; Shai Rahimipour; Desiree A Thayer; Chi-Huey Wong; M Reza Ghadiri
Antibacterial cyclic D,L-alpha-glycopeptides.
Chemical communications (Cambridge, England) 2009;(25):3693-5.
2009: Zhangyong Hong; Lei Liu; Masakazu Sugiyama; Yu Fu; Chi-Huey Wong
Concise synthesis of iminocyclitols via Petasis-type aminocyclization.
Journal of the American Chemical Society 2009;131(24):8352-3.
2009: Chung-Yi Wu; Pi-Hui Liang; Chi-Huey Wong
New development of glycan arrays.
Organic & biomolecular chemistry 2009;7(11):2247-54.
2009: Ming-Ta Sung; Yen-Ting Lai; Chia-Ying Huang; Lien-Yang Chou; Hao-Wei Shih; Wei-Chieh Cheng; Chi-Huey Wong; Che Ma
Crystal structure of the membrane-bound bifunctional transglycosylase PBP1b from Escherichia coli.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(22):8824-9.
2009: Sarah R Hanson; Elizabeth K Culyba; Tsui-Ling Sherry Hsu; Chi-Huey Wong; Jeffery W Kelly; Evan T Powers
The core trisaccharide of an N-linked glycoprotein intrinsically accelerates folding and enhances stability.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(9):3131-6.
2009: Shi-Yun Wang; Ching-Yao Su; Mengi Lin; Shao-Yung Huang; Wen-I Huang; Cheng-Chi Wang; Ying-Ta Wu; Ting-Jen R Cheng; Hui-Ming Yu; Chien-Tai Ren; Chung-Yi Wu; Chi-Huey Wong; Yih-Shyun E Cheng
HA-pseudotyped retroviral vectors for influenza antagonist screening.
Journal of biomolecular screening 2009;14(3):294-302.
2008: Chung-Sheng Shi; Guey-Yueh Shi; Shi-Ming Hsiao; Yuan-Chung Kao; Kuan-Lin Kuo; Chih-Yuan Ma; Cheng-Hsiang Kuo; Bi-Ing Chang; Chuan Fa Chang; Chun-Hung Lin; Chi-Huey Wong; Hsi-Min Hsiao; Hua-Lin Wu
Lectin-like domain of thrombomodulin binds to its specific ligand Lewis Y antigen and neutralizes lipopolysaccharide-induced inflammatory response.
Blood 2008;112(9):3661-70.
2008: Michael Giffin; Holly Heaslet; Ashraf Brik; Ying-Chuan Lin; Gabrielle Cauvi; Chi-Huey Wong; Duncan E McRee; John H Elder; C David Stout; Bruce E Torbett
A copper(I)-catalyzed 1,2,3-triazole azide-alkyne click compound is a potent inhibitor of a multidrug-resistant HIV-1 protease variant.
Journal of medicinal chemistry 2008;51(20):6263-70.
2008: Pi-Hui Liang; Masakazu Imamura; Xiangming Li; Douglass Wu; Masakazu Fujio; Richard T Guy; Bing-Ching Wu; Moriya Tsuji; Chi-Huey Wong
Quantitative microarray analysis of intact glycolipid-CD1d interaction and correlation with cell-based cytokine production.
Journal of the American Chemical Society 2008;130(37):12348-54.
2008: Clay S Bennett; Stephen M Dean; Richard J Payne; Simon Ficht; Ashraf Brik; Chi-Huey Wong
Sugar-assisted glycopeptide ligation with complex oligosaccharides: scope and limitations.
Journal of the American Chemical Society 2008;130(36):11945-52.
2008: Ming-Wei Chen; Ting-Jen Rachel Cheng; Yaoxing Huang; Jia-Tsrong Jan; Shiou-Hwa Ma; Alice L Yu; Chi-Huey Wong; David D Ho
A consensus-hemagglutinin-based DNA vaccine that protects mice against divergent H5N1 influenza viruses.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(36):13538-43.
2008: Susan Y Tseng; Cheng-Chi Wang; Chin-Wei Lin; Cheng-Lung Chen; Wen-Yueh Yu; Chung-Hsuan Chen; Chung-Yi Wu; Chi-Huey Wong
Glycan arrays on aluminum-coated glass slides.
Chemistry, an Asian journal 2008;3(8-9):1395-405.
2008: Ching-Yao Su; Shi-Yun Wang; Jiun-Jie Shie; King-Song Jeng; Nigel J Temperton; Jim-Min Fang; Chi-Huey Wong; Yih-Shyun E Cheng
In vitro evaluation of neuraminidase inhibitors using the neuraminidase-dependent release assay of hemagglutinin-pseudotyped viruses.
Antiviral research 2008;79(3):199-205.
2008: Cheng-Chi Wang; Yen-Lin Huang; Chien-Tai Ren; Chin-Wei Lin; Jung-Tung Hung; Jyh-Cherng Yu; Alice L Yu; Chung-Yi Wu; Chi-Huey Wong
Glycan microarray of Globo H and related structures for quantitative analysis of breast cancer.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(33):11661-6.
2008: Wen-Wei Chang; Chien Hsin Lee; Peishan Lee; Juway Lin; Chun-Wei Hsu; Jung-Tung Hung; Jin-Jin Lin; Jyh-Cherng Yu; Li-en Shao; John Yu; Chi-Huey Wong; Alice L Yu
Expression of Globo H and SSEA3 in breast cancer stem cells and the involvement of fucosyl transferases 1 and 2 in Globo H synthesis.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(33):11667-72.
2008: Yuki Kinjo; Bo Pei; Simone Bufali; Ravinder Raju; Stewart K Richardson; Masakazu Imamura; Masakazu Fujio; Douglass Wu; Archana Khurana; Kazuyoshi Kawahara; Chi-Huey Wong; Amy R Howell; Peter H Seeberger; Mitchell Kronenberg
Natural Sphingomonas glycolipids vary greatly in their ability to activate natural killer T cells.
Chemistry & biology 2008;15(7):654-64.
2008: Nien-Yeen Hsu; Susan Yu Tseng; Chung-Yi Wu; Chien-Tai Ren; Yuan-Chang Lee; Chi-Huey Wong; Chung-Hsuan Chen
Desorption ionization of biomolecules on metals.
Analytical chemistry 2008;80(13):5203-10.
2008: Rena D Astronomo; Hing-Ken Lee; Christopher N Scanlan; Ralph Pantophlet; Cheng-Yuan Huang; Ian A Wilson; Ola Blixt; Raymond A Dwek; Chi-Huey Wong; Dennis R Burton
A glycoconjugate antigen based on the recognition motif of a broadly neutralizing human immunodeficiency virus antibody, 2G12, is immunogenic but elicits antibodies unable to bind to the self glycans of gp120.
Journal of virology 2008;82(13):6359-68.
2008: Yves S-Y Hsieh; Cheng Chien; Sylvian K-S Liao; Shih-Fen Liao; Wei-Ting Hung; Wen-Bin Yang; Chih-Chien Lin; Ting-Jen Rachel Cheng; Chia-Chuan Chang; Jim-Min Fang; Chi-Huey Wong
Structure and bioactivity of the polysaccharides in medicinal plant Dendrobium huoshanense.
Bioorganic & medicinal chemistry 2008;16(11):6054-68.
2008: Szu-Ting Chen; Yi-Ling Lin; Ming-Ting Huang; Ming-Fang Wu; Shih-Chin James Cheng; Huan-Yao Lei; Chien-Kuo Lee; Tzyy-Wen Chiou; Chi-Huey Wong; Shie-Liang Hsieh
CLEC5A is critical for dengue-virus-induced lethal disease.
Nature 2008;453(7195):672-6.
2008: Yi-Ming Shao; Wen-Bin Yang; Tun-Hsun Kuo; Keng-Chang Tsai; Chun-Hung Lin; An-Suei Yang; Po-Huang Liang; Chi-Huey Wong
Design, synthesis, and evaluation of trifluoromethyl ketones as inhibitors of SARS-CoV 3CL protease.
Bioorganic & medicinal chemistry 2008;16(8):4652-60.
2008: Trent R Northen; Jinq-Chyi Lee; Linh Hoang; Jason Raymond; Der-Ren Hwang; Steven M Yannone; Chi-Huey Wong; Gary Siuzdak
A nanostructure-initiator mass spectrometry-based enzyme activity assay.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(10):3678-83.
2008: Sheng-Kai Wang; Po-Huang Liang; Rena D Astronomo; Tsui-Ling Sherry Hsu; Shie-Liang Hsieh; Dennis R Burton; Chi-Huey Wong
Targeting the carbohydrates on HIV-1: Interaction of oligomannose dendrons with human monoclonal antibody 2G12 and DC-SIGN.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(10):3690-5.
2008: Po-Huang Liang; Chung-Yi Wu; William A Greenberg; Chi-Huey Wong
Glycan arrays: biological and medical applications.
Current opinion in chemical biology 2008;12(1):86-92.
2008: Douglass Wu; Masakazu Fujio; Chi-Huey Wong
Glycolipids as immunostimulating agents.
Bioorganic & medicinal chemistry 2008;16(3):1073-83.
2008: Ting-Jen Rachel Cheng; Ming-Ta Sung; Hsin-Yu Liao; Yi-Fan Chang; Chia-Wei Chen; Chia-Ying Huang; Lien-Yang Chou; Yen-Da Wu; Yin-Hsuan Chen; Yih-Shyun E Cheng; Chi-Huey Wong; Che Ma; Wei-Chieh Cheng
Domain requirement of moenomycin binding to bifunctional transglycosylases and development of high-throughput discovery of antibiotics.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(2):431-6.
2008: Mu-Lin Chen; Avijit Kumar Adak; Nai-Chia Yeh; Wen-Bin Yang; Yung-Jen Chuang; Chi-Huey Wong; Kuo-Chu Hwang; Jih-Ru Reuben Hwu; Shih-Liang Hsieh; Chun-Cheng Lin
Fabrication of an oriented Fc-fused lectin microarray through boronate formation.
Angewandte Chemie (International ed. in English) 2008;47(45):8627-30.
2008: Jiun-Jie Shie; Jim-Min Fang; Chi-Huey Wong
A concise and flexible synthesis of the potent anti-influenza agents tamiflu and tamiphosphor.
Angewandte Chemie (International ed. in English) 2008;47(31):5788-91.
2008: Richard J Payne; Simon Ficht; William A Greenberg; Chi-Huey Wong
Cysteine-free peptide and glycopeptide ligation by direct aminolysis.
Angewandte Chemie (International ed. in English) 2008;47(23):4411-5.
2008: Simon Ficht; Richard J Payne; Richard T Guy; Chi-Huey Wong
Solid-phase synthesis of peptide and glycopeptide thioesters through side-chain-anchoring strategies.
Chemistry (Weinheim an der Bergstrasse, Germany) 2008;14(12):3620-9.
2007: Masakazu Sugiyama; Zhangyong Hong; Po-Huang Liang; Stephen M Dean; Lisa J Whalen; William A Greenberg; Chi-Huey Wong
D-Fructose-6-phosphate aldolase-catalyzed one-pot synthesis of iminocyclitols.
Journal of the American Chemical Society 2007;129(47):14811-7.
2007: Richard J Payne; Simon Ficht; Sishi Tang; Ashraf Brik; Yu-Ying Yang; David A Case; Chi-Huey Wong
Extended sugar-assisted glycopeptide ligations: development, scope, and applications.
Journal of the American Chemical Society 2007;129(44):13527-36.
2007: Tülay Polat; Chi-Huey Wong
Anomeric reactivity-based one-pot synthesis of heparin-like oligosaccharides.
Journal of the American Chemical Society 2007;129(42):12795-800.
2007: Jiun-Jie Shie; Jim-Min Fang; Shi-Yun Wang; Keng-Chang Tsai; Yih-Shyun E Cheng; An-Suei Yang; Shih-Chia Hsiao; Ching-Yao Su; Chi-Huey Wong
Synthesis of tamiflu and its phosphonate congeners possessing potent anti-influenza activity.
Journal of the American Chemical Society 2007;129(39):11892-3.
2007: Yi-Ming Shao; Wen-Bin Yang; Hung-Pin Peng; Min-Feng Hsu; Keng-Chang Tsai; Tun-Hsun Kuo; Andrew H-J Wang; Po-Huang Liang; Chun-Hung Lin; An-Suei Yang; Chi-Huey Wong
Structure-based design and synthesis of highly potent SARS-CoV 3CL protease inhibitors.
Chembiochem : a European journal of chemical biology 2007;8(14):1654-7.
2007: Charles P Casey; Chi-Huey Wong
Partly cloudy with a chance of showers.
ACS chemical biology 2007;2(9):573-6.
2007: Po-Huang Liang; Sheng-Kai Wang; Chi-Huey Wong
Quantitative analysis of carbohydrate-protein interactions using glycan microarrays: determination of surface and solution dissociation constants.
Journal of the American Chemical Society 2007;129(36):11177-84.
2007: Masakazu Sugiyama; Zhangyong Hong; William A Greenberg; Chi-Huey Wong
In vivo selection for the directed evolution of L-rhamnulose aldolase from L-rhamnulose-1-phosphate aldolase (RhaD).
Bioorganic & medicinal chemistry 2007;15(17):5905-11.
2007: Ming-Tzo Wei; Kuo-Feng Hua; Jowey Hsu; Artashes Karmenyan; Kai-Yu Tseng; Chi-Huey Wong; Hsien-Yeh Hsu; Arthur Chiou
The interaction of lipopolysaccharide with membrane receptors on macrophages pretreated with extract of Reishi polysaccharides measured by optical tweezers.
Optics express 2007;15(17):11020-32.
2007: Eiton Kaltgrad; Sayam Sen Gupta; Sreenivas Punna; Cheng-Yuan Huang; Aileen Chang; Chi-Huey Wong; MG Finn; Ola Blixt
Anti-carbohydrate antibodies elicited by polyvalent display on a viral scaffold.
Chembiochem : a European journal of chemical biology 2007;8(12):1455-62.
2007: Clay S Bennett; Chi-Huey Wong
Chemoenzymatic approaches to glycoprotein synthesis.
Chemical Society reviews 2007;36(8):1227-38.
2007: Kuo-Feng Hua; Hsien-Yeh Hsu; Louis Kuoping Chao; Shui-Tein Chen; Wen-Bin Yang; Jason Hsu; Chi-Huey Wong
Ganoderma lucidum polysaccharides enhance CD14 endocytosis of LPS and promote TLR4 signal transduction of cytokine expression.
Journal of cellular physiology 2007;212(2):537-50.
2007: Yu-Ying Yang; Simon Ficht; Ashraf Brik; Chi-Huey Wong
Sugar-assisted ligation in glycoprotein synthesis.
Journal of the American Chemical Society 2007;129(24):7690-701.
2007: Ya-Jen Chang; Jing-Rong Huang; Yi-Chien Tsai; Jung-Tung Hung; Douglass Wu; Masakazu Fujio; Chi-Huey Wong; Alice L Yu
Potent immune-modulating and anticancer effects of NKT cell stimulatory glycolipids.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(25):10299-304.
2007: Sarah R Hanson; Tsui-Ling Sherry Hsu; Eranthie Weerapana; Kuniyuki Kishikawa; Gabriel M Simon; Benjamin F Cravatt; Chi-Huey Wong
Tailored glycoproteomics and glycan site mapping using saccharide-selective bioorthogonal probes.
Journal of the American Chemical Society 2007;129(23):7266-7.
2007: Marie-Laure Michel; Alexandre Castro Keller; Christophe Paget; Masakazu Fujio; François Trottein; Paul B Savage; Chi-Huey Wong; Elke Schneider; Michel Dy; Maria C Leite-de-Moraes
Identification of an IL-17-producing NK1.1(neg) iNKT cell population involved in airway neutrophilia.
The Journal of experimental medicine 2007;204(5):995-1001.
2007: Tsui-Ling Sherry Hsu; Sarah R Hanson; Kuniyuki Kishikawa; Sheng-Kai Wang; Masaaki Sawa; Chi-Huey Wong
Alkynyl sugar analogs for the labeling and visualization of glycoconjugates in cells.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(8):2614-9.
2007: Zhanqian Yu; Anu R Sawkar; Lisa J Whalen; Chi-Huey Wong; Jeffery W Kelly
Isofagomine- and 2,5-anhydro-2,5-imino-D-glucitol-based glucocerebrosidase pharmacological chaperones for Gaucher disease intervention.
Journal of medicinal chemistry 2007;50(1):94-100.
2007: Kun-Chieh Cheng; Hsuan-Cheng Huang; Jenn-Han Chen; Jia-Wei Hsu; Hsu-Chieh Cheng; Chern-Han Ou; Wen-Bin Yang; Shui-Tein Chen; Chi-Huey Wong; Hsueh-Fen Juan
Ganoderma lucidum polysaccharides in human monocytic leukemia cells: from gene expression to network construction.
BMC genomics 2007;8():411.
2007: Simon Ficht; Richard J Payne; Ashraf Brik; Chi-Huey Wong
Second-generation sugar-assisted ligation: a method for the synthesis of cysteine-containing glycopeptides.
Angewandte Chemie (International ed. in English) 2007;46(31):5975-9.
2007: Nien-Yeen Hsu; Wen-Bin Yang; Chi-Huey Wong; Yuan-Chuan Lee; Reiko T Lee; Yi-Sheng Wang; Chung-Hsuan Chen
Matrix-assisted laser desorption/ionization mass spectrometry of polysaccharides with 2',4',6'-trihydroxyacetophenone as matrix.
Rapid communications in mass spectrometry : RCM 2007;21(13):2137-46.
2007: Ashraf Brik; Chi-Huey Wong
Sugar-assisted ligation for the synthesis of glycopeptides.
Chemistry (Weinheim an der Bergstrasse, Germany) 2007;13(20):5670-5.
2006: Sarah R Hanson; Lisa J Whalen; Chi-Huey Wong
Synthesis and evaluation of general mechanism-based inhibitors of sulfatases based on (difluoro)methyl phenyl sulfate and cyclic phenyl sulfamate motifs.
Bioorganic & medicinal chemistry 2006;14(24):8386-95.
2006: Ashraf Brik; Simon Ficht; Chi-Huey Wong
Strategies for the preparation of homogenous glycoproteins.
Current opinion in chemical biology 2006;10(6):638-44.
2006: Ashraf Brik; Simon Ficht; Yu-Ying Yang; Clay S Bennett; Chi-Huey Wong
Sugar-assisted ligation of N-linked glycopeptides with broad sequence tolerance at the ligation junction.
Journal of the American Chemical Society 2006;128(46):15026-33.
2006: Zhangyong Hong; Lei Liu; Che-Chang Hsu; Chi-Huey Wong
Three-step synthesis of sialic acids and derivatives.
Angewandte Chemie (International ed. in English) 2006;45(44):7417-21.
2006: Haitian Liu; Chi-Huey Wong
Characterization of a transglycosylase domain of Streptococcus pneumoniae PBP1b.
Bioorganic & medicinal chemistry 2006;14(21):7187-95.
2006: Yih-Shyun E Cheng; Kien-Hock Lo; Hsien-Hua Hsu; Yi-Ming Shao; Wen-Bin Yang; Chun-Hung Lin; Chi-Huey Wong
Screening for HIV protease inhibitors by protection against activity-mediated cytotoxicity in Escherichia coli.
Journal of virological methods 2006;137(1):82-7.
2006: Desiree A Thayer; Chi-Huey Wong
Vancomycin analogues containing monosaccharides exhibit improved antibiotic activity: a combined one-pot enzymatic glycosylation and chemical diversification strategy.
Chemistry, an Asian journal 2006;1(3):445-52.
2006: Kuo-Ting Huang; Bing-Ching Wu; Chang-Ching Lin; Shih-Chi Luo; Chinpan Chen; Chi-Huey Wong; Chun-Cheng Lin
Multi-enzyme one-pot strategy for the synthesis of sialyl Lewis X-containing PSGL-1 glycopeptide.
Carbohydrate research 2006;341(12):2151-5.
2006: Yuki Kinjo; Emmanuel Tupin; Douglass Wu; Masakazu Fujio; Raquel Garcia-Navarro; Mohammed Rafii-El-Idrissi Benhnia; Dirk Zajonc; Gil Ben-Menachem; Gary D Ainge; Gavin F Painter; Archana Khurana; Kasper Hoebe; Samuel M Behar; Bruce Beutler; Ian A Wilson; Moriya Tsuji; Timothy J Sellati; Chi-Huey Wong; Mitchell Kronenberg
Natural killer T cells recognize diacylglycerol antigens from pathogenic bacteria.
Nature immunology 2006;7(9):978-86.
2006: Kuo-I Lin; Yeong-Yi Kao; Hui-Kai Kuo; Wen-Bin Yang; Alice Chou; Lin Hsin-Hung; Alice L Yu; Chi-Huey Wong
Reishi polysaccharides induce immunoglobulin production through the TLR4/TLR2-mediated induction of transcription factor Blimp-1.
The Journal of biological chemistry 2006;281(34):24111-23.
2006: Masaaki Sawa; Tsui-Ling Sherry Hsu; Takeshi Itoh; Masakazu Sugiyama; Sarah R Hanson; Peter K Vogt; Chi-Huey Wong
Glycoproteomic probes for fluorescent imaging of fucosylated glycans in vivo.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(33):12371-6.
2006: Fu-Sen Liang; William A Greenberg; Jennifer A Hammond; Julia Hoffmann; Steven R Head; Chi-Huey Wong
Evaluation of RNA-binding specificity of aminoglycosides with DNA microarrays.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(33):12311-6.
2006: Ying-Chuan Lin; Ashraf Brik; Aymeric de Parseval; Karen Tam; Bruce E Torbett; Chi-Huey Wong; John H Elder
Altered gag polyprotein cleavage specificity of feline immunodeficiency virus/human immunodeficiency virus mutant proteases as demonstrated in a cell-based expression system.
Journal of virology 2006;80(16):7832-43.
2006: M Germana Sanna; Sheng-Kai Wang; Pedro J Gonzalez-Cabrera; Anthony Don; David Marsolais; Melanie P Matheu; Sindy H Wei; Ian Parker; Euijung Jo; Wei-Chieh Cheng; Michael D Cahalan; Chi-Huey Wong; Hugh Rosen
Enhancement of capillary leakage and restoration of lymphocyte egress by a chiral S1P1 antagonist in vivo.
Nature chemical biology 2006;2(8):434-41.
2006: Masakazu Fujio; Douglass Wu; Raquel Garcia-Navarro; David D Ho; Moriya Tsuji; Chi-Huey Wong
Structure-based discovery of glycolipids for CD1d-mediated NKT cell activation: tuning the adjuvant versus immunosuppression activity.
Journal of the American Chemical Society 2006;128(28):9022-3.
2006: Hong Qiu; Anders Gabrielsen; Hanna E Agardh; Min Wan; Anders Wetterholm; Chi-Huey Wong; Ulf Hedin; Jesper Swedenborg; Göran K Hansson; Bengt Samuelsson; Gabrielle Paulsson-Berne; Jesper Z Haeggström
Expression of 5-lipoxygenase and leukotriene A4 hydrolase in human atherosclerotic lesions correlates with symptoms of plaque instability.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(21):8161-6.
2006: Hsien-Yeh Hsu; Kuo-Feng Hua; Yu-Chang Su; Li-Chieh Chu; Shi-Chi Su; Huan-Wen Chiu; Chi-Huey Wong; Shui-Tein Chen; Chu-Wen Shieh; Su-Sing Yang; Ya-Mai Chen; Louis Kuoping Chao
Alkali-soluble polysaccharides of Rhizoclonium riparium alga induce IL-1 gene expression via protein kinase signaling pathways.
Journal of agricultural and food chemistry 2006;54(10):3558-65.
2006: Ashraf Brik; Yu-Ying Yang; Simon Ficht; Chi-Huey Wong
Sugar-assisted glycopeptide ligation.
Journal of the American Chemical Society 2006;128(17):5626-7.
2006: Ashraf Brik; Chung-Yi Wu; Chi-Huey Wong
Microtiter plate based chemistry and in situ screening: a useful approach for rapid inhibitor discovery.
Organic & biomolecular chemistry 2006;4(8):1446-57.
2006: Jinq-Chyi Lee; Chung-Yi Wu; Junefredo V Apon; Gary Siuzdak; Chi-Huey Wong
Reactivity-based one-pot synthesis of the tumor-associated antigen N3 minor octasaccharide for the development of a photocleavable DIOS-MS sugar array.
Angewandte Chemie (International ed. in English) 2006;45(17):2753-7.
2006: Manfred Brigl; Peter van den Elzen; Xiuxu Chen; Jennifer Hartt Meyers; Douglass Wu; Chi-Huey Wong; Faye Reddington; Petr A Illarianov; Gurdyal S Besra; Michael B Brenner; Jenny E Gumperz
Conserved and heterogeneous lipid antigen specificities of CD1d-restricted NKT cell receptors.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(6):3625-34.
2006: Douglass Wu; Dirk Zajonc; Masakazu Fujio; Barbara A Sullivan; Yuki Kinjo; Mitchell Kronenberg; Ian A Wilson; Chi-Huey Wong
Design of natural killer T cell activators: structure and function of a microbial glycosphingolipid bound to mouse CD1d.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(11):3972-7.
2006: Chung-Yi Wu; Ke Yung King; Chih-Jung Kuo; Jim-Min Fang; Ying-Ta Wu; Ming-Yi Ho; Chung-Lin Liao; Jiun-Jie Shie; Po-Huang Liang; Chi-Huey Wong
Stable benzotriazole esters as mechanism-based inactivators of the severe acute respiratory syndrome 3CL protease.
Chemistry & biology 2006;13(3):261-8.
2006: Lei Liu; Zhang-Yong Hong; Chi-Huey Wong
Convergent glycopeptide synthesis by traceless Staudinger ligation and enzymatic coupling.
Chembiochem : a European journal of chemical biology 2006;7(3):429-32.
2006: Ming-Hong Chuang; Ming-Shiang Wu; Wan-Lin Lo; Jaw-Town Lin; Chi-Huey Wong; Shyh-Horng Chiou
The antioxidant protein alkylhydroperoxide reductase of Helicobacter pylori switches from a peroxide reductase to a molecular chaperone function.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(8):2552-7.
2006: Fu-Sen Liang; Ashraf Brik; Ying-Chuan Lin; John H Elder; Chi-Huey Wong
Epoxide opening in water and screening in situ for rapid discovery of enzyme inhibitors in microtiter plates.
Bioorganic & medicinal chemistry 2006;14(4):1058-62.
2006: Lei Liu; Clay S Bennett; Chi-Huey Wong
Advances in glycoprotein synthesis.
Chemical communications (Cambridge, England) 2006;(1):21-33.
2006: Cheng-Yuan Huang; Desiree A Thayer; Aileen Y Chang; Michael D Best; Julia Hoffmann; Steven R Head; Chi-Huey Wong
Carbohydrate microarray for profiling the antibodies interacting with Globo H tumor antigen.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(1):15-20.
2006: Jinq-Chyi Lee; William A Greenberg; Chi-Huey Wong
Programmable reactivity-based one-pot oligosaccharide synthesis.
Nature protocols 2006;1(6):3143-52.
2006: Po-Huang Liang; Wei-Chieh Cheng; Yi-Ling Lee; Han-Pang Yu; Ying-Ta Wu; Yi-Ling Lin; Chi-Huey Wong
Novel five-membered iminocyclitol derivatives as selective and potent glycosidase inhibitors: new structures for antivirals and osteoarthritis.
Chembiochem : a European journal of chemical biology 2006;7(1):165-73.
2005: Dirk Zajonc; Igor Maricic; Douglass Wu; Ramesh C Halder; Keshab Roy; Chi-Huey Wong; Vipin Kumar; Ian A Wilson
Structural basis for CD1d presentation of a sulfatide derived from myelin and its implications for autoimmunity.
The Journal of experimental medicine 2005;202(11):1517-26.
2005: Sindy H Wei; Hugh Rosen; Melanie P Matheu; M Germana Sanna; Sheng-Kai Wang; Euijung Jo; Chi-Huey Wong; Ian Parker; Michael D Cahalan
Sphingosine 1-phosphate type 1 receptor agonism inhibits transendothelial migration of medullary T cells to lymphatic sinuses.
Nature immunology 2005;6(12):1228-35.
2005: Chung-Yi Wu; Ashraf Brik; Sheng-Kai Wang; Yu-Hsien Chen; Chi-Huey Wong
Tetrabutylammonium fluoride-mediated rapid alkylation reaction in microtiter plates for the discovery of enzyme inhibitors in situ.
Chembiochem : a European journal of chemical biology 2005;6(12):2176-80.
2005: Anu R Sawkar; Sara L Adamski-Werner; Wei-Chieh Cheng; Chi-Huey Wong; Ernest Beutler; Klaus-Peter Zimmer; Jeffery W Kelly
Gaucher disease-associated glucocerebrosidases show mutation-dependent chemical chaperoning profiles.
Chemistry & biology 2005;12(11):1235-44.
2005: Daniel A Calarese; Hing-Ken Lee; Cheng-Yuan Huang; Michael D Best; Rena D Astronomo; Robyn L Stanfield; Hermann Katinger; Dennis R Burton; Chi-Huey Wong; Ian A Wilson
Dissection of the carbohydrate specificity of the broadly neutralizing anti-HIV-1 antibody 2G12.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(38):13372-7.
2005: Jiun-Jie Shie; Jim-Min Fang; Tun-Hsun Kuo; Chih-Jung Kuo; Po-Huang Liang; Hung-Jyun Huang; Ying-Ta Wu; Jia-Tsrong Jan; Yih-Shyun E Cheng; Chi-Huey Wong
Inhibition of the severe acute respiratory syndrome 3CL protease by peptidomimetic alpha,beta-unsaturated esters.
Bioorganic & medicinal chemistry 2005;13(17):5240-52.
2005: Ashraf Brik; Chung-Yi Wu; Michael D Best; Chi-Huey Wong
Tetrabutylammonium fluoride-assisted rapid N9-alkylation on purine ring: application to combinatorial reactions in microtiter plates for the discovery of potent sulfotransferase inhibitors in situ.
Bioorganic & medicinal chemistry 2005;13(15):4622-6.
2005: Desiree A Thayer; Henry N Yu; M Carmen Galan; Chi-Huey Wong
A general strategy toward S-linked glycopeptides.
Angewandte Chemie (International ed. in English) 2005;44(29):4596-9.
2005: Ashraf Brik; Jerry Alexandratos; Ying-Chuan Lin; John H Elder; Arthur J Olson; Alexander Wlodawer; David S Goodsell; Chi-Huey Wong
1,2,3-triazole as a peptide surrogate in the rapid synthesis of HIV-1 protease inhibitors.
Chembiochem : a European journal of chemical biology 2005;6(7):1167-9.
2005: Jiun-Jie Shie; Jim-Min Fang; Chih-Jung Kuo; Tun-Hsun Kuo; Po-Huang Liang; Hung-Jyun Huang; Wen-Bin Yang; Chun-Hung Lin; Jiun-Ling Chen; Ying-Ta Wu; Chi-Huey Wong
Discovery of potent anilide inhibitors against the severe acute respiratory syndrome 3CL protease.
Journal of medicinal chemistry 2005;48(13):4469-73.
2005: Che-Chang Hsu; Zhangyong Hong; Masaru Wada; Dirk Franke; Chi-Huey Wong
Directed evolution of D-sialic acid aldolase to L-3-deoxy-manno-2-octulosonic acid (L-KDO) aldolase.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(26):9122-6.
2005: Mehdi M D Numa; Lac V Lee; Che-Chang Hsu; Kristen E. Bower; Chi-Huey Wong
Identification of novel anthrax lethal factor inhibitors generated by combinatorial Pictet-Spengler reaction followed by screening in situ.
Chembiochem : a European journal of chemical biology 2005;6(6):1002-6.
2005: Chi-Huey Wong
Protein glycosylation: new challenges and opportunities.
The Journal of organic chemistry 2005;70(11):4219-25.
2005: Guo-Wen Xing; Douglass Wu; Michael A Poles; Amir Horowitz; Moriya Tsuji; David D Ho; Chi-Huey Wong
Synthesis and human NKT cell stimulating properties of 3-O-sulfo-alpha/beta-galactosylceramides.
Bioorganic & medicinal chemistry 2005;13(8):2907-16.
2005: Yuki Kinjo; Douglass Wu; Gisen Kim; Guo-Wen Xing; Michael A Poles; David D Ho; Moriya Tsuji; Kazuyoshi Kawahara; Chi-Huey Wong; Mitchell Kronenberg
Recognition of bacterial glycosphingolipids by natural killer T cells.
Nature 2005;434(7032):520-5.
2005: Supachok Sinchaikul; Fu-Ming Pan; Ching-Wen Cheng; Chi-Huey Wong; Jim-Min Fang; Min-Jen Tseng; Shui-Tein Chen
Protein microarray using alpha-amino acids as metal tags on chips.
Bioorganic & medicinal chemistry letters 2005;15(5):1413-6.
2005: Douglass Wu; Guo-Wen Xing; Michael A Poles; Amir Horowitz; Yuki Kinjo; Barbara Sullivan; Vera Bodmer-Narkevitch; Oliver Plettenburg; Mitchell Kronenberg; Moriya Tsuji; David D Ho; Chi-Huey Wong
Bacterial glycolipids and analogs as antigens for CD1d-restricted NKT cells.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(5):1351-6.
2005: Thomas J Tolbert; Dirk Franke; Chi-Huey Wong
A new strategy for glycoprotein synthesis: ligation of synthetic glycopeptides with truncated proteins expressed in E. coli as TEV protease cleavable fusion protein.
Bioorganic & medicinal chemistry 2005;13(3):909-15.
2005: Micha Fridman; Valery Belakhov; Lac V Lee; Fu-Sen Liang; Chi-Huey Wong; Timor Baasov
Dual effect of synthetic aminoglycosides: antibacterial activity against Bacillus anthracis and inhibition of anthrax lethal factor.
Angewandte Chemie (International ed. in English) 2005;44(3):447-52.
2005: Christopher N Scanlan; Daniel A Calarese; Hing-Ken Lee; Ola Blixt; Chi-Huey Wong; Ian Wilson; Dennis Burton; Raymond A Dwek; Pauline Rudd
Antibody recognition of a carbohydrate epitope: a template for HIV vaccine design.
Advances in experimental medicine and biology 2005;564():7-8.
2004: Paul T Nyffeler; Sergio Gonzalez Durón; Michael D Burkart; Stéphane P Vincent; Chi-Huey Wong
Selectfluor: mechanistic insight and applications.
Angewandte Chemie (International ed. in English) 2004;44(2):192-212.
2004: Vani P Mocharla; Benoît Colasson; Lac V Lee; Stefanie Röper; K Barry Sharpless; Chi-Huey Wong; Hartmuth C Kolb
In situ click chemistry: enzyme-generated inhibitors of carbonic anhydrase II.
Angewandte Chemie (International ed. in English) 2004;44(1):116-20.
2004: Ran Xu; Sarah R Hanson; Zhiwen Zhang; Yu-Ying Yang; Peter G Schultz; Chi-Huey Wong
Site-specific incorporation of the mucin-type N-acetylgalactosamine-alpha-O-threonine into protein in Escherichia coli.
Journal of the American Chemical Society 2004;126(48):15654-5.
2004: Jenn-Han Chen; Yu-Wang Chang; Chen-Wen Yao; Tzong-Shi Chiueh; Su-Chin Huang; Ko-Yi Chien; An Chen; Feng-Yee Chang; Chi-Huey Wong; Yu-Ju Chen
Plasma proteome of severe acute respiratory syndrome analyzed by two-dimensional gel electrophoresis and mass spectrometry.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(49):17039-44.
2004: Ola Blixt; Steven R Head; Tony Mondala; Christopher N Scanlan; Margaret E Huflejt; Richard Alvarez; Marian C. Bryan; Fabio Fazio; Daniel A Calarese; James Stevens; Nahid Razi; David J Stevens; John J Skehel; Irma Van Die; Dennis R Burton; Ian A Wilson; Richard D Cummings; Nicolai Bovin; Chi-Huey Wong; James C Paulson
Printed covalent glycan array for ligand profiling of diverse glycan binding proteins.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(49):17033-8.
2004: Fu-Sen Liang; Sheng-Kai Wang; Takuji Nakatani; Chi-Huey Wong
Targeting RNAs with tobramycin analogues.
Angewandte Chemie (International ed. in English) 2004;43(47):6496-500.
2004: Hening Lin; Desiree A Thayer; Chi-Huey Wong; Christopher T Walsh
Macrolactamization of glycosylated peptide thioesters by the thioesterase domain of tyrocidine synthetase.
Chemistry & biology 2004;11(12):1635-42.
2004: Sarah Hanson; Michael D Best; Marian C. Bryan; Chi-Huey Wong
Chemoenzymatic synthesis of oligosaccharides and glycoproteins.
Trends in biochemical sciences 2004;29(12):656-63.
2004: Hsien-Yeh Hsu; Kuo-Feng Hua; Chun-Cheng Lin; Chun-Hung Lin; Jason Hsu; Chi-Huey Wong
Extract of Reishi polysaccharides induces cytokine expression via TLR4-modulated protein kinase signaling pathways.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(10):5989-99.
2004: Sarah R Hanson; Michael D Best; Chi-Huey Wong
Sulfatases: structure, mechanism, biological activity, inhibition, and synthetic utility.
Angewandte Chemie (International ed. in English) 2004;43(43):5736-63.
2004: michael chien; Jing-Long Cheng; Wen-Teish Chang; Ming-Hsun Tien; Chien-Ming Tsao; Yung-Han Chang; Hwan-You Chang; Jung-Feng Hsieh; Chi-Huey Wong; Shui-Tein Chen
Polysaccharides of Ganoderma lucidum alter cell immunophenotypic expression and enhance CD56+ NK-cell cytotoxicity in cord blood.
Bioorganic & medicinal chemistry 2004;12(21):5603-9.
2004: Hung-Sen Chen; Yow-Fu Tsai; Steven Lin; Chia-Ching Lin; Kay-Hooi Khoo; Chun-Hung Lin; Chi-Huey Wong
Studies on the immuno-modulating and anti-tumor activities of Ganoderma lucidum (Reishi) polysaccharides.
Bioorganic & medicinal chemistry 2004;12(21):5595-601.
2004: Andreas Heine; John G Luz; Chi-Huey Wong; Ian A Wilson
Analysis of the class I aldolase binding site architecture based on the crystal structure of 2-deoxyribose-5-phosphate aldolase at 0.99A resolution.
Journal of molecular biology 2004;343(4):1019-34.
2004: Junjie Liu; Mehdi M D Numa; Haitian Liu; Shi-Jung Huang; Pamela Sears; Alexander R Shikhman; Chi-Huey Wong
Synthesis and high-throughput screening of N-acetyl-beta-hexosaminidase inhibitor libraries targeting osteoarthritis.
The Journal of organic chemistry 2004;69(19):6273-83.
2004: Paul T Nyffeler; Nicholas A Boyle; Laxman Eltepu; Chi-Huey Wong; Albert Eschenmoser; Richard A Lerner; Paul Wentworth
Dihydrogen trioxide (HOOOH) is generated during the thermal reaction between hydrogen peroxide and ozone.
Angewandte Chemie (International ed. in English) 2004;43(35):4656-9.
2004: Chuan Fa Chang; Chin-Wen Ho; Chung-Yi Wu; Tsrong-An Chao; Chi-Huey Wong; Chun-Hung Lin
Discovery of picomolar slow tight-binding inhibitors of alpha-fucosidase.
Chemistry & biology 2004;11(9):1301-6.
2004: Marian C. Bryan; Fabio Fazio; Hing-Ken Lee; Cheng-Yuan Huang; Aileen Chang; Michael D Best; Daniel A Calarese; Ola Blixt; James C Paulson; Dennis Burton; Ian A Wilson; Chi-Huey Wong
Covalent display of oligosaccharide arrays in microtiter plates.
Journal of the American Chemical Society 2004;126(28):8640-1.
2004: Chung-Yi Wu; Jia-Tsrong Jan; Shiou-Hwa Ma; Chih-Jung Kuo; Hsueh-Fen Juan; Yih-Shyun E Cheng; Hsien-Hua Hsu; Hsuan-Cheng Huang; Douglass Wu; Ashraf Brik; Fu-Sen Liang; Rai-Shung Liu; Jim-Min Fang; Shui-Tein Chen; Po-Huang Liang; Chi-Huey Wong
Small molecules targeting severe acute respiratory syndrome human coronavirus.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(27):10012-7.
2004: Eli Chapman; Michael D Best; Sarah R Hanson; Chi-Huey Wong
Sulfotransferases: structure, mechanism, biological activity, inhibition, and synthetic utility.
Angewandte Chemie (International ed. in English) 2004;43(27):3526-48.
2004: Ting-Jen Cheng; Ashraf Brik; Chi-Huey Wong; Chen-Chen Kan
Model system for high-throughput screening of novel human immunodeficiency virus protease inhibitors in Escherichia coli.
Antimicrobial agents and chemotherapy 2004;48(7):2437-47.
2004: Marian C. Bryan; Lac V Lee; Chi-Huey Wong
High-throughput identification of fucosyltransferase inhibitors using carbohydrate microarrays.
Bioorganic & medicinal chemistry letters 2004;14(12):3185-8.
2004: Michael D Best; Ashraf Brik; Eli Chapman; Lac V Lee; Wei-Chieh Cheng; Chi-Huey Wong
Rapid discovery of potent sulfotransferase inhibitors by diversity-oriented reaction in microplates followed by in situ screening.
Chembiochem : a European journal of chemical biology 2004;5(6):811-9.
2004: Lac V Lee; Kristen E. Bower; Fu-Sen Liang; Jin Shi; Douglass Wu; Steven J Sucheck; Peter K Vogt; Chi-Huey Wong
Inhibition of the proteolytic activity of anthrax lethal factor by aminoglycosides.
Journal of the American Chemical Society 2004;126(15):4774-5.
2004: Ching-Wen Cheng; Kuo-Chin Lin; Fu-Ming Pan; Supachok Sinchaikul; Chi-Huey Wong; Wei-Chih Su; Ching-Hsiang Hsu; Shui-Tein Chen
Facile synthesis of metal-chelating peptides on chip for protein array.
Bioorganic & medicinal chemistry letters 2004;14(8):1987-90.
2004: Fabio Agnelli; Steven J Sucheck; Kenneth A Marby; David Rabuka; Su-Lan Yao; Pamela Sears; Fu-Sen Liang; Chi-Huey Wong
Dimeric aminoglycosides as antibiotics.
Angewandte Chemie (International ed. in English) 2004;43(12):1562-6.
2004: Sergio G Durón; Tülay Polat; Chi-Huey Wong
N-(phenylthio)-epsilon-caprolactam: a new promoter for the activation of thioglycosides.
Organic letters 2004;6(5):839-41.
2004: Henry N Yu; Jun-ichi Furukawa; Tsuyoshi Ikeda; Chi-Huey Wong
Novel efficient routes to heparin monosaccharides and disaccharides achieved via regio- and stereoselective glycosidation.
Organic letters 2004;6(5):723-6.
2004: Marie-Pierre Heck; Stéphane P Vincent; Brion W Murray; François Bellamy; Chi-Huey Wong; Charles Mioskowski
Cyclic amidine sugars as transition-state analogue inhibitors of glycosidases: potent competitive inhibitors of mannosidases.
Journal of the American Chemical Society 2004;126(7):1971-9.
2004: Chien-Hung Chou; Chung-Shieh Wu; Ching-Hui Chen; Lung-Dai Lu; Suvarn S Kulkarni; Chi-Huey Wong; Shang-Cheng Hung
Regioselective glycosylation of neamine core: a facile entry to kanamycin B related analogues.
Organic letters 2004;6(4):585-8.
2004: Hing-Ken Lee; Christopher N Scanlan; Cheng-Yuan Huang; Aileen Y Chang; Daniel A Calarese; Raymond A Dwek; Pauline M Rudd; Dennis R Burton; Ian A Wilson; Chi-Huey Wong
Reactivity-based one-pot synthesis of oligomannoses: defining antigens recognized by 2G12, a broadly neutralizing anti-HIV-1 antibody.
Angewandte Chemie (International ed. in English) 2004;43(8):1000-3.
2004: Zhiwen Zhang; Jeff Gildersleeve; Yu-Ying Yang; Ran Xu; Joseph A Loo; Sean Uryu; Chi-Huey Wong; Peter G Schultz
A new strategy for the synthesis of glycoproteins.
Science (New York, N.Y.) 2004;303(5656):371-3.
2004: Dirk Franke; Che-Chang Hsu; Chi-Huey Wong
Directed evolution of aldolases.
Methods in enzymology 2004;388():224-38.
2004: Thomas J Tolbert; Chi-Huey Wong
Subtilisin-catalyzed glycopeptide condensation.
Methods in molecular biology (Clifton, N.J.) 2004;283():267-79.
2004: Thomas J Tolbert; Chi-Huey Wong
Conjugation of glycopeptide thioesters to expressed protein fragments: semisynthesis of glycosylated interleukin-2.
Methods in molecular biology (Clifton, N.J.) 2004;283():255-66.
2004: Dagmar Klostermeier; Pamela Sears; Chi-Huey Wong; David P Millar; James R Williamson
A three-fluorophore FRET assay for high-throughput screening of small-molecule inhibitors of ribosome assembly.
Nucleic acids research 2004;32(9):2707-15.
2003: Ashraf Brik; John Muldoon; Ying-Chuan Lin; John H Elder; David S Goodsell; Arthur J Olson; Valery V Fokin; K Barry Sharpless; Chi-Huey Wong
Rapid diversity-oriented synthesis in microtiter plates for in situ screening of HIV protease inhibitors.
Chembiochem : a European journal of chemical biology 2003;4(11):1246-8.
2003: Chung-Yi Wu; Chuan Fa Chang; Jenny Szu-Yu Chen; Chi-Huey Wong; Chun-Hung Lin
Rapid diversity-oriented synthesis in microtiter plates for in situ screening: discovery of potent and selective alpha-fucosidase inhibitors.
Angewandte Chemie (International ed. in English) 2003;42(38):4661-4.
2003: Thomas K Ritter; Kwok-Kong T Mong; Haitian Liu; Takuji Nakatani; Chi-Huey Wong
A programmable one-pot oligosaccharide synthesis for diversifying the sugar domains of natural products: a case study of vancomycin.
Angewandte Chemie (International ed. in English) 2003;42(38):4657-60.
2003: Ten Feizi; Fabio Fazio; Wengang Chai; Chi-Huey Wong
Carbohydrate microarrays - a new set of technologies at the frontiers of glycomics.
Current opinion in structural biology 2003;13(5):637-45.
2003: Tony K-K Mong; Lac V Lee; Jillian R Brown; Jeffrey D Esko; Chi-Huey Wong
Synthesis of N-acetyllactosamine derivatives with variation in the aglycon moiety for the study of inhibition of sialyl Lewis x expression.
Chembiochem : a European journal of chemical biology 2003;4(9):835-40.
2003: Dirk Franke; Timothy Machajewski; Che-Chang Hsu; Chi-Huey Wong
One-pot synthesis of L-Fructose using coupled multienzyme systems based on rhamnulose-1-phosphate aldolase.
The Journal of organic chemistry 2003;68(17):6828-31.
2003: Lac V Lee; Michael Mitchell; Shih-Jung Huang; Valery V Fokin; K Barry Sharpless; Chi-Huey Wong
A potent and highly selective inhibitor of human alpha-1,3-fucosyltransferase via click chemistry.
Journal of the American Chemical Society 2003;125(32):9588-9.
2003: Haitian Liu; Thomas K Ritter; Reiko Sadamoto; Pamela Sears; Min Wu; Chi-Huey Wong
Acceptor specificity and inhibition of the bacterial cell-wall glycosyltransferase MurG.
Chembiochem : a European journal of chemical biology 2003;4(7):603-9.
2003: Masaru Wada; Che-Chang Hsu; Dirk Franke; Michael Mitchell; Andreas Heine; Ian Wilson; Chi-Huey Wong
Directed evolution of N-acetylneuraminic acid aldolase to catalyze enantiomeric aldol reactions.
Bioorganic & medicinal chemistry 2003;11(9):2091-8.
2003: Chi Ching Mak; Ashraf Brik; Deborah L Lerner; John H Elder; Garrett M Morris; Arthur J Olson; Chi-Huey Wong
Design and synthesis of broad-based mono- and bi- cyclic inhibitors of FIV and HIV proteases.
Bioorganic & medicinal chemistry 2003;11(9):2025-40.
2003: Tony K-K Mong; Cheng-Yuan Huang; Chi-Huey Wong
A new reactivity-based one-pot synthesis of N-acetyllactosamine oligomers.
The Journal of organic chemistry 2003;68(6):2135-42.
2003: Haitian Liu; Lei Wang; Ansgar Brock; Chi-Huey Wong; Peter G Schultz
A method for the generation of glycoprotein mimetics.
Journal of the American Chemical Society 2003;125(7):1702-3.
2003: Tony Kwok-Kong Mong; Hing-Ken Lee; Sergio G Duron; Chi-Huey Wong
Reactivity-based one-pot total synthesis of fucose GM1 oligosaccharide: a sialylated antigenic epitope of small-cell lung cancer.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(3):797-802.
2003: Eli Chapman; Marian C. Bryan; Chi-Huey Wong
Mechanistic studies of beta-arylsulfotransferase IV.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(3):910-5.
2003: Ashraf Brik; Chi-Huey Wong
HIV-1 protease: mechanism and drug discovery.
Organic & biomolecular chemistry 2003;1(1):5-14.
2003: Grace DeSantis; Junjie Liu; David P Clark; Andreas Heine; Ian A Wilson; Chi-Huey Wong
Structure-based mutagenesis approaches toward expanding the substrate specificity of D-2-deoxyribose-5-phosphate aldolase.
Bioorganic & medicinal chemistry 2003;11(1):43-52.
2003: Chi-Huey Wong; Fu-Sen Liang
Surface plasmon resonance study of RNA-aminoglycoside interactions.
Methods in enzymology 2003;362():340-53.
2003: Chi-Huey Wong; Marian C. Bryan
Sugar arrays in microtiter plates.
Methods in enzymology 2003;362():218-25.
2002: Eli Chapman; Sheng Ding; Peter G Schultz; Chi-Huey Wong
A potent and highly selective sulfotransferase inhibitor.
Journal of the American Chemical Society 2002;124(49):14524-5.
2002: Fabio Fazio; Marian C. Bryan; Ola Blixt; James C Paulson; Chi-Huey Wong
Synthesis of sugar arrays in microtiter plate.
Journal of the American Chemical Society 2002;124(48):14397-402.
2002: Anu R Sawkar; Wei-Chieh Cheng; Ernest Beutler; Chi-Huey Wong; William E Balch; Jeffery W Kelly
Chemical chaperones increase the cellular activity of N370S beta -glucosidase: a therapeutic strategy for Gaucher disease.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(24):15428-33.
2002: Kwok-Kong T Mong; Chi-Huey Wong
Reactivity-based one-pot synthesis of a Lewis Y carbohydrate hapten: a colon-rectal cancer antigen determinant.
Angewandte Chemie (International ed. in English) 2002;41(21):4087-90.
2002: Marjolein M G M Thunnissen; Björn Andersson; Bengt Samuelsson; Chi-Huey Wong; Jesper Z Haeggström
Crystal structures of leukotriene A4 hydrolase in complex with captopril and two competitive tight-binding inhibitors.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(12):1648-50.
2002: Paul T Nyffeler; Chang-Hsing Liang; Kathryn M Koeller; Chi-Huey Wong
The chemistry of amine-azide interconversion: catalytic diazotransfer and regioselective azide reduction.
Journal of the American Chemical Society 2002;124(36):10773-8.
2002: Michael Mitchell; Feng Tian; Lac V Lee; Chi-Huey Wong
Synthesis and evaluation of transition-state analogue inhibitors of alpha-1,3-fucosyltransferase.
Angewandte Chemie (International ed. in English) 2002;41(16):3041-4.
2002: Reiko Sadamoto; Kenichi Niikura; Pamela Sears; Haitian Liu; Chi-Huey Wong; Akarat Suksomcheep; Fusao Tomita; Kenji Monde; Shin-Ichiro Nishimura
Cell-wall engineering of living bacteria.
Journal of the American Chemical Society 2002;124(31):9018-9.
2002: Ashraf Brik; Ying-Chuan Lin; John Elder; Chi-Huey Wong
A quick diversity-oriented amide-forming reaction to optimize P-subsite residues of HIV protease inhibitors.
Chemistry & biology 2002;9(8):891-6.
2002: Oliver Plettenburg; Vera Bodmer-Narkevitch; Chi-Huey Wong
Synthesis of alpha-galactosyl ceramide, a potent immunostimulatory agent.
The Journal of organic chemistry 2002;67(13):4559-64.
2002: Thomas J Tolbert; Chi-Huey Wong
New methods for proteomic research: preparation of proteins with N-terminal cysteines for labeling and conjugation.
Angewandte Chemie (International ed. in English) 2002;41(12):2171-4.
2002: Marian C. Bryan; Oliver Plettenburg; Pamela Sears; David Rabuka; Shirley Wacowich-Sgarbi; Chi-Huey Wong
Saccharide display on microtiter plates.
Chemistry & biology 2002;9(6):713-20.
2002: Junjie Liu; Chi-Huey Wong
Aldolase-catalyzed asymmetric synthesis of novel pyranose synthons as a new entry to heterocycles and epothilones.
Angewandte Chemie (International ed. in English) 2002;41(8):1404-7.
2002: Takuya Kanemitsu; Chi-Huey Wong; Osamu Kanie
Solid-phase synthesis of oligosaccharides and on-resin quantitative monitoring using gated decoupling (13)C NMR.
Journal of the American Chemical Society 2002;124(14):3591-9.
2002: Yuan-Yuan Wang; Kay-Hooi Khoo; Shui-Tein Chen; Chun-Cheng Lin; Chi-Huey Wong; Chun-Hung Lin
Studies on the immuno-modulating and antitumor activities of Ganoderma lucidum (Reishi) polysaccharides: functional and proteomic analyses of a fucose-containing glycoprotein fraction responsible for the activities.
Bioorganic & medicinal chemistry 2002;10(4):1057-62.
2002: Chao-Tan Guo; Xue-Long Sun; Osamu Kanie; Kennedy Francis Shortridge; Takashi Suzuki; Daisei Miyamoto; Kazuya I P J Hidari; Chi-Huey Wong; Yasuo Suzuki
An O-glycoside of sialic acid derivative that inhibits both hemagglutinin and sialidase activities of influenza viruses.
Glycobiology 2002;12(3):183-90.
2002: Eli Chapman; Chi-Huey Wong
A pH sensitive colorometric assay for the high-throughput screening of enzyme inhibitors and substrates: a case study using kinases.
Bioorganic & medicinal chemistry 2002;10(3):551-5.
2001: M Izumi; G J Shen; S Wacowich-Sgarbi; T Nakatani; Oliver Plettenburg; Chi-Huey Wong
Microbial glycosyltransferases for carbohydrate synthesis: alpha-2,3-sialyltransferase from Neisseria gonorrheae.
Journal of the American Chemical Society 2001;123(44):10909-18.
2001: Andreas Heine; G DeSantis; John G Luz; M Mitchell; Chi-Huey Wong; Ian A Wilson
Observation of covalent intermediates in an enzyme mechanism at atomic resolution.
Science (New York, N.Y.) 2001;294(5541):369-74.
2001: Haitian Liu; Reiko Sadamoto; Pamela Sears; Chi-Huey Wong
An efficient chemoenzymatic strategy for the synthesis of wild-type and vancomycin-resistant bacterial cell-wall precursors: UDP-N-acetylmuramyl-peptides.
Journal of the American Chemical Society 2001;123(40):9916-7.
2001: I A Kozlov; Shenlan Mao; Y Xu; Xuefei Huang; L Lee; P S Sears; Changshou Gao; A R Coyle; Kim D Janda; Chi-Huey Wong
Synthesis of solid-supported mirror-image sugars: a novel method for selecting receptors for cellular-surface carbohydrates.
Chembiochem : a European journal of chemical biology 2001;2(10):741-6.
2001: Bernd Bühler; Ying-Chuan Lin; G Morris; Arthur J Olson; Chi-Huey Wong; Douglas D Richman; John H Elder; Bruce E Torbett
Viral evolution in response to the broad-based retroviral protease inhibitor TL-3.
Journal of virology 2001;75(19):9502-8.
2001: Junjie Liu; Alexander R Shikhman; Martin Lotz; Chi-Huey Wong
Hexosaminidase inhibitors as new drug candidates for the therapy of osteoarthritis.
Chemistry & biology 2001;8(7):701-11.
2001: VD Le; Chi Ching Mak; Ying-Chuan Lin; John H Elder; Chi-Huey Wong
Structure-activity studies of FIV and HIV protease inhibitors containing allophenylnorstatine.
Bioorganic & medicinal chemistry 2001;9(5):1185-95.
2001: Pamela Sears; Chi-Huey Wong
Toward automated synthesis of oligosaccharides and glycoproteins.
Science (New York, N.Y.) 2001;291(5512):2344-50.
2001: M G Silvestri; Chi-Huey Wong
Opening of thiiranes: preparation of orthogonal protected 2-thioglyceraldehyde.
The Journal of organic chemistry 2001;66(3):910-4.
2001: Chi Ching Mak; VD Le; Ying-Chuan Lin; John H Elder; Chi-Huey Wong
Design, synthesis, and biological evaluation of HIV/FIV protease inhibitors incorporating a conformationally constrained macrocycle with a small P3' residue.
Bioorganic & medicinal chemistry letters 2001;11(2):219-22.
2001: Kathryn M Koeller; Chi-Huey Wong
Enzymes for chemical synthesis.
Nature 2001;409(6817):232-40.
2000: Steven J Sucheck; Chi-Huey Wong
RNA as a target for small molecules.
Current opinion in chemical biology 2000;4(6):678-86.
2000: A Romero; Chi-Huey Wong
Chemo-enzymatic total synthesis of 3-epiaustraline, australine, and 7-epialexine.
The Journal of organic chemistry 2000;65(24):8264-8.
2000: Kathryn M Koeller; Chi-Huey Wong
Complex carbohydrate synthesis tools for glycobiologists: enzyme-based approach and programmable one-pot strategies.
Glycobiology 2000;10(11):1157-69.
2000: T L Sheppard; Chi-Huey Wong; Gerald F Joyce
Nucleoglycoconjugates: design and synthesis of a new class of DNA-carbohydrate conjugates.
Angewandte Chemie (International ed. in English) 2000;39(20):3660-3.
2000: A Düffels; Luke G Green; R Lenz; Steven V Ley; Stéphane P Vincent; Chi-Huey Wong
Chemoenzymatic synthesis of L-galactosylated dimeric sialyl Lewis X structures employing alpha-1,3-fucosyltransferase V.
Bioorganic & medicinal chemistry 2000;8(10):2519-25.
2000: Michael D Burkart; M Izumi; Eli Chapman; C H Lin; Chi-Huey Wong
Regeneration of PAPS for the enzymatic synthesis of sulfated oligosaccharides.
The Journal of organic chemistry 2000;65(18):5565-74.
2000: Michael D Burkart; Stéphane P Vincent; A Düffels; Brion W Murray; Steven V Ley; Chi-Huey Wong
Chemo-enzymatic synthesis of fluorinated sugar nucleotide: useful mechanistic probes for glycosyltransferases.
Bioorganic & medicinal chemistry 2000;8(8):1937-46.
2000: Kathryn M Koeller; Chi-Huey Wong
Emerging themes in medicinal glycoscience.
Nature biotechnology 2000;18(8):835-41.
2000: Stéphane P Vincent; A Schleyer; Chi-Huey Wong
Asymmetric Strecker synthesis of C-glycopeptide.
The Journal of organic chemistry 2000;65(14):4440-3.
2000: M Takayanagi; T Flessner; Chi-Huey Wong
A strategy for the solution-phase parallel synthesis of N-(pyrrolidinylmethyl)hydroxamic acids.
The Journal of organic chemistry 2000;65(12):3811-5.
2000: Kathryn M Koeller; M E Smith; Chi-Huey Wong
Chemoenzymatic synthesis of PSGL-1 glycopeptides: sulfation on tyrosine affects glycosyltransferase-catalyzed synthesis of the O-glycan.
Bioorganic & medicinal chemistry 2000;8(5):1017-25.
2000: Ying-Chuan Lin; Zachary Q Beck; T Lee; VD Le; Garrett M Morris; Arthur J Olson; Chi-Huey Wong; John H Elder
Alteration of substrate and inhibitor specificity of feline immunodeficiency virus protease.
Journal of virology 2000;74(10):4710-20.
2000: X S Ye; Chi-Huey Wong
Anomeric reactivity-based one-pot oligosaccharide synthesis: a rapid route to oligosaccharide libraries.
The Journal of organic chemistry 2000;65(8):2410-31.
2000: VD Le; Chi-Huey Wong
Synthesis of 2-substituted polyhydroxytetrahydropyrimidines (N-hydroxy cyclic guanidino-sugars): transition-state mimics of enzymatic glycosidic cleavage.
The Journal of organic chemistry 2000;65(8):2399-409.
2000: Kathryn M Koeller; Chi-Huey Wong
Chemoenzymatic synthesis of sialyl-trimeric-Lewis x.
Chemistry (Weinheim an der Bergstrasse, Germany) 2000;6(7):1243-51.
2000: V Wittmann; A K Datta; Kathryn M Koeller; Chi-Huey Wong
Chemoenzymatic synthesis and fluorescent visualization of cell-surface selectin-bound sialyl Lewis x derivatives.
Chemistry (Weinheim an der Bergstrasse, Germany) 2000;6(1):162-71.
1999: G J Shen; A K Datta; M Izumi; Kathryn M Koeller; Chi-Huey Wong
Expression of alpha2,8/2,9-polysialyltransferase from Escherichia coli K92. Characterization of the enzyme and its reaction products.
The Journal of biological chemistry 1999;274(49):35139-46.
1999: Michael D Burkart; Chi-Huey Wong
A continuous assay for the spectrophotometric analysis of sulfotransferases using aryl sulfotransferase IV.
Analytical biochemistry 1999;274(1):131-7.
1999: G Weitz-Schmidt; K W Gong; Chi-Huey Wong
Selectin/glycoconjugate binding assays for the identification and optimization of selectin antagonists.
Analytical biochemistry 1999;273(1):81-8.
1999: Shenlan Mao; Changshou Gao; CH Lo; Peter Wirsching; Chi-Huey Wong; Kim D Janda
Phage-display library selection of high-affinity human single-chain antibodies to tumor-associated carbohydrate antigens sialyl Lewisx and Lewisx.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(12):6953-8.
1999: C M Huwe; T J Woltering; J Jiricek; G Weitz-Schmidt; Chi-Huey Wong
Design, synthesis and biological evaluation of aryl-substituted sialyl Lewis X mimetics prepared via cross-metathesis of C-fucopeptides.
Bioorganic & medicinal chemistry 1999;7(5):773-88.
1999: C C Lin; F Morís-Varas; G Weitz-Schmidt; Chi-Huey Wong
Synthesis of sialyl Lewis x mimetics as selectin inhibitors by enzymatic aldol condensation reactions.
Bioorganic & medicinal chemistry 1999;7(3):425-33.
1999: S Takayama; S J Chung; Y Igarashi; Y Ichikawa; A Sepp; R I Lechler; J Wu; T Hayashi; Gary Siuzdak; Chi-Huey Wong
Selective inhibition of beta-1,4- and alpha-1,3-galactosyltransferases: donor sugar-nucleotide based approach.
Bioorganic & medicinal chemistry 1999;7(2):401-9.
1998: S J Chung; S Takayama; Chi-Huey Wong
Acceptor substrate-based selective inhibition of galactosyltransferases.
Bioorganic & medicinal chemistry letters 1998;8(23):3359-64.
1998: R Wischnat; R Martin; S Takayama; Chi-Huey Wong
Chemoenzymatic synthesis of iminocyclitol derivatives: a useful library strategy for the development of selective fucosyltransfer enzymes inhibitors.
Bioorganic & medicinal chemistry letters 1998;8(23):3353-8.
1998: Chao-Tan Guo; Chi-Huey Wong; Tetsuya Kajimoto; T Miura; Y Ida; Lekh Raj Juneja; M J Kim; H Masuda; Takashi Suzuki; Yasuo Suzuki
Synthetic sialylphosphatidylethanolamine derivatives bind to human influenza A viruses and inhibit viral infection.
Glycoconjugate journal 1998;15(11):1099-108.
1998: C Y Tsai; W K Park; G Weitz-Schmidt; Beat Ernst; Chi-Huey Wong
Synthesis of sialyl Lewis X mimetics using the Ugi four-component reaction.
Bioorganic & medicinal chemistry letters 1998;8(17):2333-8.
1998: R Martin; K L Witte; Chi-Huey Wong
The synthesis and enzymatic incorporation of sialic acid derivatives for use as tools to study the structure, activity, and inhibition of glycoproteins and other glycoconjugates.
Bioorganic & medicinal chemistry 1998;6(8):1283-92.
1998: Chi-Huey Wong; M Hendrix; E S Priestley; William A Greenberg
Specificity of aminoglycoside antibiotics for the A-site of the decoding region of ribosomal RNA.
Chemistry & biology 1998;5(7):397-406.
1998: Pamela Sears; Chi-Huey Wong
Enzyme action in glycoprotein synthesis.
Cellular and molecular life sciences : CMLS 1998;54(3):223-52.
1998: T Lee; Gary S Laco; Bruce E Torbett; Howard S Fox; Deborah L Lerner; John H Elder; Chi-Huey Wong
Analysis of the S3 and S3' subsite specificities of feline immunodeficiency virus (FIV) protease: development of a broad-based protease inhibitor efficacious against FIV, SIV, and HIV in vitro and ex vivo.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(3):939-44.
1997: M Koketsu; T Nitoda; H Sugino; Lekh Raj Juneja; M Kim; T Yamamoto; N Abe; Tetsuya Kajimoto; Chi-Huey Wong
Synthesis of a novel sialic acid derivative (sialylphospholipid) as an antirotaviral agent.
Journal of medicinal chemistry 1997;40(21):3332-5.
1997: J Wu; S Takayama; Chi-Huey Wong; Gary Siuzdak
Quantitative electrospray mass spectrometry for the rapid assay of enzyme inhibitors.
Chemistry & biology 1997;4(9):653-7.
1997: M Hendrix; E S Priestley; Gerald F Joyce; Chi-Huey Wong
Direct observation of aminoglycoside-RNA interactions by surface plasmon resonance.
Journal of the American Chemical Society 1997;119(16):3641-8.
1997: R Wang; Darryl Steensma; Y Takaoka; J W Yun; T Kajimoto; Chi-Huey Wong
A search for pyrophosphate mimics for the development of substrates and inhibitors of glycosyltransferases.
Bioorganic & medicinal chemistry 1997;5(4):661-72.
1997: T Hayashi; Brion W Murray; R Wang; Chi-Huey Wong
A chemoenzymatic synthesis of UDP-(2-deoxy-2-fluoro)-galactose and evaluation of its interaction with galactosyltransferase.
Bioorganic & medicinal chemistry 1997;5(3):497-500.
1997: Kim D Janda; L C Lo; CH Lo; M M Sim; R Wang; Chi-Huey Wong; Richard A Lerner
Chemical selection for catalysis in combinatorial antibody libraries.
Science (New York, N.Y.) 1997;275(5302):945-8.
1997: M W Cappi; W J Moree; L Qiao; Thomas Marron; G Weitz-Schmidt; Chi-Huey Wong
Synthesis of novel 6-amido-6-deoxy-l-galactose derivatives as sialyl Lewis X mimetics.
Bioorganic & medicinal chemistry 1997;5(2):283-96.
1997: Brion W Murray; V Wittmann; Michael D Burkart; S C Hung; Chi-Huey Wong
Mechanism of human alpha-1,3-fucosyltransferase V: glycosidic cleavage occurs prior to nucleophilic attack.
Biochemistry 1997;36(4):823-31.
1997: C H Lin; Brion W Murray; I R Ollmann; Chi-Huey Wong
Why is CMP-ketodeoxyoctonate highly unstable?
Biochemistry 1997;36(4):780-5.
1997: S Takayama; G J McGarvey; Chi-Huey Wong
Microbial aldolases and transketolases: new biocatalytic approaches to simple and complex sugars.
Annual review of microbiology 1997;51():285-310.
1996: X Qian; F Morís-Varas; MC Fitzgerald; Chi-Huey Wong
C2-symmetrical tetrahydroxyazepanes as inhibitors of glycosidases and HIV/FIV proteases.
Bioorganic & medicinal chemistry 1996;4(12):2055-69.
1996: P Sears; Chi-Huey Wong
Intervention of carbohydrate recognition by proteins and nucleic acids.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(22):12086-93.
1996: Brion W Murray; S Takayama; J Schultz; Chi-Huey Wong
Mechanism and specificity of human alpha-1,3-fucosyltransferase V.
Biochemistry 1996;35(34):11183-95.
1996: W Fitz; P B Rosenthal; Chi-Huey Wong
Synthesis and inhibitory properties of a thiomethylmercuric sialic acid with application to the X-ray structure determination of 9-O-acetylsialic acid esterase from influenza C virus.
Bioorganic & medicinal chemistry 1996;4(8):1349-53.
1996: T Uchiyama; T J Woltering; W Wong; C C Lin; T Kajimoto; M Takebayashi; G Weitz-Schmidt; T Asakura; M Noda; Chi-Huey Wong
Design and synthesis of C-linked fucosides as inhibitors of E-selectin.
Bioorganic & medicinal chemistry 1996;4(7):1149-65.
1996: M Hendrix; Chi-Huey Wong
A chemo-enzymatic approach to the study of carbohydrate recognition in biological systems.
Enantiomer 1996;1(4-6):305-10.
1996: C De Luca; M Lansing; F Crescenzi; I Martini; G J Shen; M O'Regan; Chi-Huey Wong
Overexpression, one-step purification and characterization of UDP-glucose dehydrogenase and UDP-N-acetylglucosamine pyrophosphorylase.
Bioorganic & medicinal chemistry 1996;4(1):131-41.
1995: C H Lin; M Shimazaki; Chi-Huey Wong; M Koketsu; Lekh Raj Juneja; M Kim
Enzymatic synthesis of a sialyl Lewis X dimer from egg yolk as an inhibitor of E-selectin.
Bioorganic & medicinal chemistry 1995;3(12):1625-30.
1995: J H Hogg; I R Ollmann; Jesper Z Haeggström; Anders Wetterholm; Bengt Samuelsson; Chi-Huey Wong
Amino hydroxamic acids as potent inhibitors of leukotriene A4 hydrolase.
Bioorganic & medicinal chemistry 1995;3(10):1405-15.
1995: E Garcia-Junceda; G J Shen; R Alajarin; Chi-Huey Wong
Cloning and overexpression of rhamnose isomerase and fucose isomerase.
Bioorganic & medicinal chemistry 1995;3(10):1349-55.
1995: Anders Wetterholm; Jesper Z Haeggström; Bengt Samuelsson; W Yuan; B Munoz; Chi-Huey Wong
Potent and selective inhibitors of leukotriene A4 hydrolase: effects on purified enzyme and human polymorphonuclear leukocytes.
The Journal of pharmacology and experimental therapeutics 1995;275(1):31-7.
1995: I R Ollmann; J H Hogg; B Muñoz; Jesper Z Haeggström; Bengt Samuelsson; Chi-Huey Wong
Investigation of the inhibition of leukotriene A4 hydrolase.
Bioorganic & medicinal chemistry 1995;3(7):969-95.
1995: E Garcia-Junceda; G J Shen; T Sugai; Chi-Huey Wong
A new strategy for the cloning, overexpression and one step purification of three DHAP-dependent aldolases: rhamnulose-1-phosphate aldolase, fuculose-1-phosphate aldolase and tagatose-1,6-diphosphate aldolase.
Bioorganic & medicinal chemistry 1995;3(7):945-53.
1995: Enrico STURA; S Ghosh; E Garcia-Junceda; L Chen; Chi-Huey Wong; Ian A Wilson
Crystallization and preliminary crystallographic data for class I deoxyribose-5-phosphate aldolase from Escherichia coli: an application of reverse screening.
Proteins 1995;22(1):67-72.
1995: T Sugai; C H Lin; G J Shen; Chi-Huey Wong
CMP-KDO synthetase: overproduction and application to the synthesis of CMP-KDO and analogs.
Bioorganic & medicinal chemistry 1995;3(3):313-20.
1994: L Provencher; Darryl Steensma; Chi-Huey Wong
Five-membered ring azasugars as potent inhibitors of alpha-L-rhamnosidase (naringinase) from Penicillium decumbens.
Bioorganic & medicinal chemistry 1994;2(11):1179-88.
1994: B Munoz; C Z Giam; Chi-Huey Wong
Alpha-ketoamide Phe-Pro isostere as a new core structure for the inhibition of HIV protease.
Bioorganic & medicinal chemistry 1994;2(10):1085-90.
1994: I Henderson; E Garcia-Junceda; K K Liu; Y L Chen; G J Shen; Chi-Huey Wong
Cloning, overexpression and isolation of the type II FDP aldolase from E. coli for specificity study and synthetic application.
Bioorganic & medicinal chemistry 1994;2(8):837-43.
1994: S Aoki; H Kondo; Chi-Huey Wong
Glycosyl phosphites as glycosylation reagents.
Methods in enzymology 1994;247():193-211.
1994: Y Ichikawa; R Wang; Chi-Huey Wong
Regeneration of sugar nucleotide for enzymatic oligosaccharide synthesis.
Methods in enzymology 1994;247():107-27.
1993: W Yuan; B Munoz; Chi-Huey Wong; Jesper Z Haeggström; Anders Wetterholm; Bengt Samuelsson
Development of selective tight-binding inhibitors of leukotriene A4 hydrolase.
Journal of medicinal chemistry 1993;36(2):211-20.
1992: Chi-Huey Wong; K K Liu; T Kajimoto; L Chen; Z Zhong; Y Ichikawa; G J Shen
Developing better enzymes for organic synthesis.
Annals of the New York Academy of Sciences 1992;672():343-51.
1992: Chi-Huey Wong
Engineering enzymes for chemoenzymatic synthesis. Part 2: Modifying proteases for peptide synthesis.
Trends in biotechnology 1992;10(11):378-81.
1992: Chi-Huey Wong
Engineering enzymes for chemoenzymatic synthesis. Part I: Practical routes to aza-sugars and complex carbohydrates.
Trends in biotechnology 1992;10(10):337-41.
1992: Y Ichikawa; G C Look; Chi-Huey Wong
Enzyme-catalyzed oligosaccharide synthesis.
Analytical biochemistry 1992;202(2):215-38.
1991: Chi-Huey Wong; G J Shen; R L Pederson; Y F Wang; W J Hennen
Enzymatic catalysis in organic synthesis.
Methods in enzymology 1991;202():591-620.