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Hector Wong

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Intensive Care Units, Pediatric

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TOP 3
William Hanna; Hector R Wong
Pediatric sepsis: challenges and adjunctive therapies.
Patrick D Solan; Alvin Denenberg; Katherine E Dunsmore; Kelli Odoms; Basilia Zingarelli; Hector R Wong
A novel role for matrix metalloproteinase-8 in sepsis.
Hector R Wong
Clinical review: sepsis and septic shock--the potential of gene arrays.

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All Publications

2013: William Hanna; Hector R Wong
Pediatric sepsis: challenges and adjunctive therapies.
Critical care clinics 2013;29(2):203-22.
2012: Patrick D Solan; Alvin Denenberg; Katherine E Dunsmore; Kelli Odoms; Basilia Zingarelli; Hector R Wong
A novel role for matrix metalloproteinase-8 in sepsis.
Critical care medicine 2012;40(2):379-87.
2012: Hector R Wong
Clinical review: sepsis and septic shock--the potential of gene arrays.
Critical care (London, England) 2012;16(1):204.
2011: Hector R Wong; Geoffrey L Allen; Nick Anas; Rajit K Basu; Michael T Bigham; Paul A Checchia; Ranjit S Chima; Natalie Cvijanovich; Lesley A Doughty; Robert J Freishtat; Jennifer M Kaplan; Richard Lin; Keith Meyer; Sue E Poynter; Thomas P Shanley; Erika Stalets; Ken Tegtmeyer; Neal J Thomas; Brian M Varisco; Derek S Wheeler; Frederick E Barr
Validation of a gene expression-based subclassification strategy for pediatric septic shock.
Critical care medicine 2011;39(11):2511-7.
2011: Hector R Wong; Heidi J Dalton
The PICU perspective on monitoring hemodynamics and oxygen transport.
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 2011;12(4 Suppl):S66-8.
2011: Derek S Wheeler; Katherine E Dunsmore; Alvin G Denenberg; Larissa Muething; Sue E Poynter; Hector R Wong
Biological activity of truncated C-terminus human heat shock protein 72.
Immunology letters 2011;135(1-2):173-9.
2011: Michael J Hobson; Hector R Wong
Finding new therapies for sepsis: the need for patient stratification and the use of genetic biomarkers.
Critical care (London, England) 2011;15(6):1009.
2011: Rajit K Basu; Michael T Bigham; Paul A Checchia; Natalie Cvijanovich; Prasad Devarajan; Robert J Freishtat; Stuart L Goldstein; Richard Lin; Keith Meyer; Thomas P Shanley; Stephen W Standage; Neal J Thomas; Derek S Wheeler; Geoffrey L Allen; Nick Anas; Hector R Wong
Identification of candidate serum biomarkers for severe septic shock-associated kidney injury via microarray.
Critical care (London, England) 2011;15(6):R273.
2011: James L Wynn; Geoffrey L Allen; Nick Anas; Sharon Banschbach; Eileen Beckman; Michael T Bigham; Paul A Checchia; Natalie Z Cvijanovich; Robert J Freishtat; Richard Lin; Keith Meyer; Thomas P Shanley; Neal J Thomas; Hector R Wong
The influence of developmental age on the early transcriptomic response of children with septic shock.
Molecular medicine (Cambridge, Mass.) 2011;17(11-12):1146-56.
2011: Derek S Wheeler; John S Giuliano; Patrick M Lahni; Alvin Denenberg; Hector R Wong; Basilia Zingarelli
The immunomodulatory effects of albumin in vitro and in vivo.
Advances in pharmacological sciences 2011;2011():691928.
2011: Stephen W Standage; Hector R Wong
Biomarkers for pediatric sepsis and septic shock.
Expert review of anti-infective therapy 2011;9(1):71-9.
2010: Michael J Hobson; Hector R Wong
Genetic association research: understanding its challenges and limitations.
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 2010;11(6):762-3.
2010: Hector R Wong; Robert J Freishtat; Marie Monaco; Kelli Odoms; Thomas P Shanley
Leukocyte subset-derived genomewide expression profiles in pediatric septic shock.
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 2010;11(3):349-55.
2010: Derrick J N Dauplaise; Sean J Barnett; Jason S Frischer; Hector R Wong
Decompressive abdominal laparotomy for abdominal compartment syndrome in an unengrafted bone marrow recipient with septic shock.
Critical care research and practice 2010;2010():.
2009: Derek S Wheeler; Basilia Zingarelli; William J Wheeler; Hector R Wong
Novel pharmacologic approaches to the management of sepsis: targeting the host inflammatory response.
Recent patents on inflammation & allergy drug discovery 2009;3(2):96-112.
2009: Basilia Zingarelli; Paul W Hake; Michael O'Connor; Timothy J Burroughs; Hector R Wong; Joseph S Solomkin; Alex B Lentsch
Lung injury after hemorrhage is age dependent: role of peroxisome proliferator-activated receptor gamma.
Critical care medicine 2009;37(6):1978-87.
2009: Hector R Wong; Natalie Cvijanovich; Geoffrey L Allen; Richard Lin; Nick Anas; Keith Meyer; Robert J Freishtat; Marie Monaco; Kelli Odoms; Bhuvaneswari Sakthivel; Thomas P Shanley
Genomic expression profiling across the pediatric systemic inflammatory response syndrome, sepsis, and septic shock spectrum.
Critical care medicine 2009;37(5):1558-66.
2009: Nadine Huber; Nozomu Sakai; Thorsten Eismann; Thomas Shin; Satoshi Kuboki; John Blanchard; Rebecca Schuster; Michael J Edwards; Hector R Wong; Alex B Lentsch
Age-related decrease in proteasome expression contributes to defective nuclear factor-kappaB activation during hepatic ischemia/reperfusion.
Hepatology (Baltimore, Md.) 2009;49(5):1718-28.
2009: Hector R Wong; Natalie Cvijanovich; Richard Lin; Geoffrey L Allen; Neal J Thomas; Douglas F Willson; Robert J Freishtat; Nick Anas; Keith Meyer; Paul A Checchia; Marie Monaco; Kelli Odom; Thomas P Shanley
Identification of pediatric septic shock subclasses based on genome-wide expression profiling.
BMC medicine 2009;7():34.
2009: Derek S Wheeler; Margaret A Chase; Albert P Senft; Sue E Poynter; Hector R Wong; Kristen Page
Extracellular Hsp72, an endogenous DAMP, is released by virally infected airway epithelial cells and activates neutrophils via Toll-like receptor (TLR)-4.
Respiratory research 2009;10():31.
2008: John S Giuliano; Patrick M Lahni; Michael T Bigham; Peter B Manning; David P Nelson; Hector R Wong; Derek S Wheeler
Plasma angiopoietin-2 levels increase in children following cardiopulmonary bypass.
Intensive care medicine 2008;34(10):1851-7.
2008: Patricia A Abboud; Patrick M Lahni; Kristen Page; John S Giuliano; Kelli Harmon; Katherine E Dunsmore; Hector R Wong; Derek S Wheeler
The role of endogenously produced extracellular hsp72 in mononuclear cell reprogramming.
Shock (Augusta, Ga.) 2008;30(3):285-92.
2008: Derek S Wheeler; Patrick M Lahni; Alvin Denenberg; Sue E Poynter; Hector R Wong; James A Cook; Basilia Zingarelli
Induction of endotoxin tolerance enhances bacterial clearance and survival in murine polymicrobial sepsis.
Shock (Augusta, Ga.) 2008;30(3):267-73.
2008: Hector R Wong; Natalie Cvijanovich; Derek S Wheeler; Michael T Bigham; Marie Monaco; Kelli Odoms; William L Macias; Mark D Williams
Interleukin-8 as a stratification tool for interventional trials involving pediatric septic shock.
American journal of respiratory and critical care medicine 2008;178(3):276-82.
2008: Natalie Cvijanovich; Thomas P Shanley; Richard Lin; Geoffrey L Allen; Neal J Thomas; Paul Checchia; Nick Anas; Robert J Freishtat; Marie Monaco; Kelli Odoms; Bhuvaneswari Sakthivel; Hector R Wong
Validating the genomic signature of pediatric septic shock.
Physiological genomics 2008;34(1):127-34.
2008: Derek S Wheeler; Prasad Devarajan; Qing Ma; Kelli Harmon; Marie Monaco; Natalie Cvijanovich; Hector R Wong
Serum neutrophil gelatinase-associated lipocalin (NGAL) as a marker of acute kidney injury in critically ill children with septic shock.
Critical care medicine 2008;36(4):1297-303.
2008: Bin Zhao; Lei Sun; Michael Haas; Alvin Denenberg; Hector R Wong; Thomas P Shanley
PP2A regulates upstream members of the c-jun N-terminal kinase mitogen-activated protein kinase signaling pathway.
Shock (Augusta, Ga.) 2008;29(2):181-8.
2008: Patricia A Abboud; Paul W Hake; Timothy J Burroughs; Kelli Odoms; Michael O'Connor; Prajakta Mangeshkar; Hector R Wong; Basilia Zingarelli
Therapeutic effect of epigallocatechin-3-gallate in a mouse model of colitis.
European journal of pharmacology 2008;579(1-3):411-7.
2008: Hector R Wong; Kelli Odoms; Bhuvaneswari Sakthivel
Divergence of canonical danger signals: the genome-level expression patterns of human mononuclear cells subjected to heat shock or lipopolysaccharide.
BMC immunology 2008;9():24.
2008: Michael T Bigham; Patrick Brady; Peter B Manning; Brian R Jacobs; Thomas R Kimball; Hector R Wong
Therapeutic application of intrapericardial tissue plasminogen activator in a 4-month-old child with complex fibropurulent pericarditis.
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 2008;9(1):e1-4.
2007: John S Giuliano; Patrick M Lahni; Kelli Harmon; Hector R Wong; Lesley A Doughty; Joseph A Carcillo; Basilia Zingarelli; Vikas P Sukhatme; Samir M Parikh; Derek S Wheeler
Admission angiopoietin levels in children with septic shock.
Shock (Augusta, Ga.) 2007;28(6):650-654.
2007: Margaret A Chase; Derek S Wheeler; Kristin M Lierl; Valerie S Hughes; Hector R Wong; Kristen Page
Hsp72 induces inflammation and regulates cytokine production in airway epithelium through a TLR4- and NF-kappaB-dependent mechanism.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(9):6318-24.
2007: Basilia Zingarelli; Paul W Hake; Prajakta Mangeshkar; Michael O'Connor; Timothy J Burroughs; Giovanna Piraino; Alvin Denenberg; Hector R Wong
Diverse cardioprotective signaling mechanisms of peroxisome proliferator-activated receptor-gamma ligands, 15-deoxy-Delta12,14-prostaglandin J2 and ciglitazone, in reperfusion injury: role of nuclear factor-kappaB, heat shock factor 1, and Akt.
Shock (Augusta, Ga.) 2007;28(5):554-63.
2007: Thomas P Shanley; Natalie Cvijanovich; Richard Lin; Geoffrey L Allen; Neal J Thomas; Allan doctor; Meena Kalyanaraman; Nancy M Tofil; Scott Penfil; Marie Monaco; Kelli Odoms; Michael Barnes; Bhuvaneswari Sakthivel; Bruce Aronow; Hector R Wong
Genome-level longitudinal expression of signaling pathways and gene networks in pediatric septic shock.
Molecular medicine (Cambridge, Mass.) 2007;13(9-10):495-508.
2007: Derek S Wheeler; Patrick M Lahni; Paul W Hake; Alvin Denenberg; Hector R Wong; Connie Snead; John D Catravas; Basilia Zingarelli
The green tea polyphenol epigallocatechin-3-gallate improves systemic hemodynamics and survival in rodent models of polymicrobial sepsis.
Shock (Augusta, Ga.) 2007;28(3):353-9.
2007: Hector R Wong; Thomas P Shanley; Bhuvaneswari Sakthivel; Natalie Cvijanovich; Richard Lin; Geoffrey L Allen; Neal J Thomas; Allan doctor; Meena Kalyanaraman; Nancy M Tofil; Scott Penfil; Marie Monaco; Mary Ann Tagavilla; Kelli Odoms; Katherine Dunsmore; Michael Barnes; Bruce Aronow
Genome-level expression profiles in pediatric septic shock indicate a role for altered zinc homeostasis in poor outcome.
Physiological genomics 2007;30(2):146-55.
2007: Derek S Wheeler; Patrick M Lahni; Kelli Odoms; Brian R Jacobs; Joseph A Carcillo; Lesley A Doughty; Hector R Wong
Extracellular heat shock protein 60 (Hsp60) levels in children with septic shock.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2007;56(5):216-9.
2007: Esmaeil Mortaz; Frank A Redegeld; Katherine E Dunsmore; Kelli Odoms; Hector R Wong; Frans P Nijkamp; Ferdi Engels
Stimulation of cysteinyl leukotriene production in mast cells by heat shock and acetylsalicylic acid.
European journal of pharmacology 2007;561(1-3):214-9.
2007: Satoshi Kuboki; Rebecca Schuster; John Blanchard; Timothy A Pritts; Hector R Wong; Alex B Lentsch
Role of heat shock protein 70 in hepatic ischemia-reperfusion injury in mice.
American journal of physiology. Gastrointestinal and liver physiology 2007;292(4):G1141-9.
2007: Derek S Wheeler; Hector R Wong
Heat shock response and acute lung injury.
Free radical biology & medicine 2007;42(1):1-14.
2007: Satoshi Kuboki; Tomohisa Okaya; Rebecca Schuster; John Blanchard; Alvin Denenberg; Hector R Wong; Alex B Lentsch
Hepatocyte NF-kappaB activation is hepatoprotective during ischemia-reperfusion injury and is augmented by ischemic hypothermia.
American journal of physiology. Gastrointestinal and liver physiology 2007;292(1):G201-7.
2006: Rajesh Aneja; Kelli Odoms; Katherine Dunsmore; Thomas P Shanley; Hector R Wong
Extracellular heat shock protein-70 induces endotoxin tolerance in THP-1 cells.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(10):7184-92.
2006: Kristen Page; Valerie S Hughes; G W Bennett; Hector R Wong
German cockroach proteases regulate matrix metalloproteinase-9 in human bronchial epithelial cells.
Allergy 2006;61(8):988-95.
2006: Katherine E Dunsmore; Alvin Denenberg; Kristen Page; Hector R Wong
Mechanism and function of heat shock-dependent IkappaBalpha expression.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2006;55(6):254-9.
2006: Angela L Morrison; Martin Dinges; Kristen D Singleton; Kelli Odoms; Hector R Wong; Paul E Wischmeyer
Glutamine's protection against cellular injury is dependent on heat shock factor-1.
American journal of physiology. Cell physiology 2006;290(6):C1625-32.
2006: Esmaeil Mortaz; Frank A Redegeld; Nanne Bloksma; Katherine E Dunsmore; Alvin Denenberg; Hector R Wong; Frans P Nijkamp; Ferdi Engels
Induction of HSP70 is dispensable for anti-inflammatory action of heat shock or NSAIDs in mast cells.
Experimental hematology 2006;34(4):414-23.
2006: N William Parilla; Valerie S Hughes; Kristin M Lierl; Hector R Wong; Kristen Page
CpG DNA modulates interleukin 1beta-induced interleukin-8 expression in human bronchial epithelial (16HBE14o-) cells.
Respiratory research 2006;7():84.
2006: Esmaeil Mortaz; Frank A Redegeld; Frans P Nijkamp; Hector R Wong; Ferdi Engels
Acetylsalicylic acid-induced release of HSP70 from mast cells results in cell activation through TLR pathway.
Experimental hematology 2006;34(1):8-18.
2005: Hector R Wong
Translation.
Critical care medicine 2005;33(12 Suppl):S404-6.
2005: Hector R Wong; Katherine E Dunsmore; Kristen Page; Thomas P Shanley
Heat shock-mediated regulation of MKP-1.
American journal of physiology. Cell physiology 2005;289(5):C1152-8.
2005: Esmaeil Mortaz; Frank A Redegeld; Maurice W van der Heijden; Hector R Wong; Frans P Nijkamp; Ferdi Engels
Mast cell activation is differentially affected by heat shock.
Experimental hematology 2005;33(8):944-52.
2005: Yichen Lai; Lina Du; Katherine E Dunsmore; Larry W Jenkins; Hector R Wong; Robert S B Clark
Selectively increasing inducible heat shock protein 70 via TAT-protein transduction protects neurons from nitrosative stress and excitotoxicity.
Journal of neurochemistry 2005;94(2):360-6.
2005: Derek S Wheeler; Lyle E Fisher; John D Catravas; Brian R Jacobs; Joseph A Carcillo; Hector R Wong
Extracellular hsp70 levels in children with septic shock.
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 2005;6(3):308-11.
2005: Marianne Nimah; Bin Zhao; Alvin Denenberg; Orlando Bueno; Jeffery D Molkentin; Hector R Wong; Thomas P Shanley
Contribution of MKP-1 regulation of p38 to endotoxin tolerance.
Shock (Augusta, Ga.) 2005;23(1):80-7.
2004: Lauren Sanlorenzo; Bin Zhao; Donn H Spight; Alvin Denenberg; Kristen Page; Hector R Wong; Thomas P Shanley
Heat shock inhibition of lipopolysaccharide-mediated tumor necrosis factor expression is associated with nuclear induction of MKP-1 and inhibition of mitogen-activated protein kinase activation.
Critical care medicine 2004;32(11):2284-92.
2004: Rajesh Aneja; Kelli Odoms; Alvin Denenberg; Hector R Wong
Theaflavin, a black tea extract, is a novel anti-inflammatory compound.
Critical care medicine 2004;32(10):2097-103.
2004: Derek S Wheeler; John D Catravas; Kelli Odoms; Alvin Denenberg; Vivek Malhotra; Hector R Wong
Epigallocatechin-3-gallate, a green tea-derived polyphenol, inhibits IL-1 beta-dependent proinflammatory signal transduction in cultured respiratory epithelial cells.
The Journal of nutrition 2004;134(5):1039-44.
2004: Basilia Zingarelli; Paul W Hake; Michael O'Connor; Alvin Denenberg; Hector R Wong; Sue Kong; Bruce Aronow
Differential regulation of activator protein-1 and heat shock factor-1 in myocardial ischemia and reperfusion injury: role of poly(ADP-ribose) polymerase-1.
American journal of physiology. Heart and circulatory physiology 2004;286(4):H1408-15.
2004: Kelli Odoms; Thomas P Shanley; Hector R Wong
Short-term modulation of interleukin-1beta signaling by hyperoxia: uncoupling of IkappaB kinase activation and NF-kappaB-dependent gene expression.
American journal of physiology. Lung cellular and molecular physiology 2004;286(3):L554-62.
2004: Zoltán H Németh; Hector R Wong; Kelli Odoms; Edwin A Deitch; Csaba Szabó; E Sylvester Vizi; György Haskó
Proteasome inhibitors induce inhibitory kappa B (I kappa B) kinase activation, I kappa B alpha degradation, and nuclear factor kappa B activation in HT-29 cells.
Molecular pharmacology 2004;65(2):342-9.
2004: Rajesh Aneja; Paul W Hake; Timothy J Burroughs; Alvin Denenberg; Hector R Wong; Basilia Zingarelli
Epigallocatechin, a green tea polyphenol, attenuates myocardial ischemia reperfusion injury in rats.
Molecular medicine (Cambridge, Mass.) 2004;10(1-6):55-62.
2003: Maeve Sheehan; Hector R Wong; Paul W Hake; Basilia Zingarelli
Parthenolide improves systemic hemodynamics and decreases tissue leukosequestration in rats with polymicrobial sepsis.
Critical care medicine 2003;31(9):2263-70.
2003: Thomas P Shanley; Hector R Wong
Molecular genetics in the pediatric intensive care unit.
Critical care clinics 2003;19(3):577-94.
2003: Derek S Wheeler; Katherine E Dunsmore; Hector R Wong
Intracellular delivery of HSP70 using HIV-1 Tat protein transduction domain.
Biochemical and biophysical research communications 2003;301(1):54-9.
2003: Basilia Zingarelli; Maeve Sheehan; Hector R Wong
Nuclear factor-kappaB as a therapeutic target in critical care medicine.
Critical care medicine 2003;31(1 Suppl):S105-11.
2002: Vivek Malhotra; Neil W Kooy; Alvin Denenberg; Katherine E Dunsmore; Hector R Wong
Ablation of the heat shock factor-1 increases susceptibility to hyperoxia-mediated cellular injury.
Experimental lung research 2002;28(8):609-22.
2002: Khaled Bshesh; Bin Zhao; Donn H Spight; Italo Biaggioni; Igor Feokistov; Alvin Denenberg; Hector R Wong; Thomas P Shanley
The A2A receptor mediates an endogenous regulatory pathway of cytokine expression in THP-1 cells.
Journal of leukocyte biology 2002;72(5):1027-36.
2002: Bruce J Grossman; Thomas P Shanley; Alvin Denenberg; Bin Zhao; Hector R Wong
Phosphatase inhibition leads to activation of IkappaB kinase in murine macrophages.
Biochemical and biophysical research communications 2002;297(5):1264-9.
2002: Philip C Chen; Derek S Wheeler; Vivek Malhotra; Kelli Odoms; Alvin Denenberg; Hector R Wong
A green tea-derived polyphenol, epigallocatechin-3-gallate, inhibits IkappaB kinase activation and IL-8 gene expression in respiratory epithelium.
Inflammation 2002;26(5):233-41.
2002: Timothy A Pritts; Quan Wang; Xiaoyan Sun; David R Fischer; Eric S Hungness; Josef E Fischer; Hector R Wong; Per-Olof Hasselgren
The stress response decreases NF-kappaB activation in liver of endotoxemic mice.
Shock (Augusta, Ga.) 2002;18(1):33-7.
2002: Bruce J Grossman; Thomas P Shanley; Kelli Odoms; Katherine E Dunsmore; Alvin Denenberg; Hector R Wong
Temporal and mechanistic effects of heat shock on LPS-mediated degradation of IkappaBalpha in macrophages.
Inflammation 2002;26(3):129-37.
2002: Maeve Sheehan; Hector R Wong; Paul W Hake; Vivek Malhotra; Michael O'Connor; Basilia Zingarelli
Parthenolide, an inhibitor of the nuclear factor-kappaB pathway, ameliorates cardiovascular derangement and outcome in endotoxic shock in rodents.
Molecular pharmacology 2002;61(5):953-63.
2002: Hector R Wong; Kelli Odoms; Alvin Denenberg; Geoffrey L Allen; Thomas P Shanley
Hyperoxia prolongs tumor necrosis factor-alpha-mediated activation of NF-kappaB: role of IkappaB kinase.
Shock (Augusta, Ga.) 2002;17(4):274-9.
2002: Timothy A Pritts; Eric S Hungness; Dan D Hershko; Bruce W Robb; Xiaoyan Sun; Guang-Ju Luo; Josef E Fischer; Hector R Wong; Per-Olof Hasselgren
Proteasome inhibitors induce heat shock response and increase IL-6 expression in human intestinal epithelial cells.
American journal of physiology. Regulatory, integrative and comparative physiology 2002;282(4):R1016-26.
2002: Basilia Zingarelli; Paul W Hake; Zequan Yang; Michael O'Connor; Alvin Denenberg; Hector R Wong
Absence of inducible nitric oxide synthase modulates early reperfusion-induced NF-kappaB and AP-1 activation and enhances myocardial damage.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(3):327-42.
2002: Vivek Malhotra; Tonyia Eaves-Pyles; Kelli Odoms; Gina Quaid; Thomas P Shanley; Hector R Wong
Heat shock inhibits activation of NF-kappaB in the absence of heat shock factor-1.
Biochemical and biophysical research communications 2002;291(3):453-7.
2002: Gary L Kohn; Hector R Wong; Khaled Bshesh; Bin Zhao; Niti Vasi; Alvin Denenberg; Christopher Morris; James Stark; Thomas P Shanley
Heat shock inhibits tnf-induced ICAM-1 expression in human endothelial cells via I kappa kinase inhibition.
Shock (Augusta, Ga.) 2002;17(2):91-7.
2002: Basilia Zingarelli; Paul W Hake; Alvin Denenberg; Hector R Wong
Sesquiterpene lactone parthenolide, an inhibitor of IkappaB kinase complex and nuclear factor-kappaB, exerts beneficial effects in myocardial reperfusion injury.
Shock (Augusta, Ga.) 2002;17(2):127-34.
2002: Maeve Sheehan; Hector R Wong; Paul W Hake; Basilia Zingarelli
Protective effects of isohelenin, an inhibitor of nuclear factor kappaB, in endotoxic shock in rats.
Journal of endotoxin research 2002;8(2):99-107.
2002: Hector R Wong
ARDS. The future.
Critical care clinics 2002;18(1):177-96.
2002: Jeffrey M Pearl; David P Nelson; Jenni L Raake; Peter B Manning; Steven M Schwartz; Lisa Koons; Thomas P Shanley; Hector R Wong; Jodie Y Duffy
Inhaled nitric oxide increases endothelin-1 levels: a potential cause of rebound pulmonary hypertension.
Critical care medicine 2002;30(1):89-93.
2002: Vivek Malhotra; Hector R Wong
Interactions between the heat shock response and the nuclear factor-kappa B signaling pathway.
Critical care medicine 2002;30(1 Suppl):S89-95.
2001: Tonyia Eaves-Pyles; Hector R Wong; Kelli Odoms; R B Pyles
Salmonella flagellin-dependent proinflammatory responses are localized to the conserved amino and carboxyl regions of the protein.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(12):7009-16.
2001: Katherine E Dunsmore; P G Chen; Hector R Wong
Curcumin, a medicinal herbal compound capable of inducing the heat shock response.
Critical care medicine 2001;29(11):2199-204.
2001: Derek S Wheeler; Hector R Wong
The impact of molecular biology on the practice of pediatric critical care medicine.
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 2001;2(4):299-310.
2001: Basilia Zingarelli; Zequan Yang; Paul W Hake; Alvin Denenberg; Hector R Wong
Absence of endogenous interleukin 10 enhances early stress response during post-ischaemic injury in mice intestine.
Gut 2001;48(5):610-22.
2001: Thomas P Shanley; Niti Vasi; Alvin Denenberg; Hector R Wong
The serine/threonine phosphatase, PP2A: endogenous regulator of inflammatory cell signaling.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(2):966-72.
2001: Brian R Jacobs; Lori Barr; Richard J Brilli; K A Lyons; Hector R Wong
Intracatheter nitroglycerin infusion fails to prevent catheter-related venous thrombosis: a randomized, controlled trial.
Intensive care medicine 2001;27(1):187-92.
2000: Quan Wang; X Sun; Timothy A Pritts; Hector R Wong; P O Hasselgren
Induction of the stress response increases interleukin-6 production in the intestinal mucosa of endotoxaemic mice.
Clinical science (London, England : 1979) 2000;99(6):489-96.
2000: Thomas P Shanley; MA Ryan; Tonyia Eaves-Pyles; Hector R Wong
Heat shock inhibits phosphorylation of I-kappaBalpha.
Shock (Augusta, Ga.) 2000;14(4):447-50.
2000: Timothy A Pritts; Quan Wang; Xiaoyan Sun; MR Moon; David R Fischer; Josef E Fischer; Hector R Wong; Per-Olof Hasselgren
Induction of the stress response in vivo decreases nuclear factor-kappa B activity in jejunal mucosa of endotoxemic mice.
Archives of surgery (Chicago, Ill. : 1960) 2000;135(7):860-6.
2000: R L Mazor; IY Menendez; MA Ryan; M A Fiedler; Hector R Wong
Sesquiterpene lactones are potent inhibitors of interleukin 8 gene expression in cultured human respiratory epithelium.
Cytokine 2000;12(3):239-45.
2000: Geoffrey L Allen; IY Menendez; MA Ryan; R L Mazor; JR Wispé; M A Fiedler; Hector R Wong
Hyperoxia synergistically increases TNF-alpha-induced interleukin-8 gene expression in A549 cells.
American journal of physiology. Lung cellular and molecular physiology 2000;278(2):L253-60.
2000: Tonyia Eaves-Pyles; Hector R Wong; J Wesley Alexander
Sodium arsenite induces the stress response in the gut and decreases bacterial translocation in a burned mouse model with gut-derived sepsis.
Shock (Augusta, Ga.) 2000;13(4):314-9.
1999: R Moon; Timothy A Pritts; AA Parikh; Josef E Fischer; AL Salzman; M Ryan; Hector R Wong; Per-Olof Hasselgren
Stress response decreases the interleukin-1beta-induced production of complement component C3 in human intestinal epithelial cells.
Clinical science (London, England : 1979) 1999;97(3):331-7.
1999: Hector R Wong; IY Menendez
Sesquiterpene lactones inhibit inducible nitric oxide synthase gene expression in cultured rat aortic smooth muscle cells.
Biochemical and biophysical research communications 1999;262(2):375-80.
1999: Hector R Wong; MA Ryan; IY Menendez; JR Wispé
Heat shock activates the I-kappaBalpha promoter and increases I-kappaBalpha mRNA expression.
Cell stress & chaperones 1999;4(1):1-7.
1998: S C Thomas; MA Ryan; Thomas P Shanley; Hector R Wong
Induction of the stress response with prostaglandin A1 increases I-kappaBalpha gene expression.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1998;12(13):1371-8.
1998: Hector R Wong; IY Menendez; MA Ryan; Alvin Denenberg; JR Wispé
Increased expression of heat shock protein-70 protects A549 cells against hyperoxia.
The American journal of physiology 1998;275(4 Pt 1):L836-41.
1998: O Ayad; James M Stark; M M Fiedler; IY Menendez; MA Ryan; Hector R Wong
The heat shock response inhibits RANTES gene expression in cultured human lung epithelium.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(5):2594-9.
1998: O Ayad; Hector R Wong
Nitric oxide decreases surfactant protein A gene expression in H441 cells.
Critical care medicine 1998;26(7):1277-82.
1998: E Gilad; Hector R Wong; Basilia Zingarelli; Laszlo Virag; Michael O'Connor; Andrew L Salzman; Csaba Szabó
Melatonin inhibits expression of the inducible isoform of nitric oxide synthase in murine macrophages: role of inhibition of NFkappaB activation.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1998;12(9):685-93.
1998: Hector R Wong
Potential protective role of the heat shock response in sepsis.
New horizons (Baltimore, Md.) 1998;6(2):194-200.
1997: Hector R Wong; M Ryan; IY Menendez; Alvin Denenberg; JR Wispé
Heat shock protein induction protects human respiratory epithelium against nitric oxide-mediated cytotoxicity.
Shock (Augusta, Ga.) 1997;8(3):213-8.
1997: Hector R Wong; JR Wispé
The stress response and the lung.
The American journal of physiology 1997;273(1 Pt 1):L1-9.
1997: Hector R Wong; M Ryan; JR Wispé
Stress response decreases NF-kappaB nuclear translocation and increases I-kappaBalpha expression in A549 cells.
The Journal of clinical investigation 1997;99(10):2423-8.
1997: Marc S Arkovitz; Csaba Szabó; Victor F Garcia; Hector R Wong; JR Wispé
Differential effects of hyperoxia on the inducible and constitutive isoforms of nitric oxide synthase in the lung.
Shock (Augusta, Ga.) 1997;7(5):345-50.
1997: Hector R Wong; M Ryan; JR Wispé
The heat shock response inhibits inducible nitric oxide synthase gene expression by blocking I kappa-B degradation and NF-kappa B nuclear translocation.
Biochemical and biophysical research communications 1997;231(2):257-63.
1997: Hector R Wong; M Ryan; S Gebb; JR Wispé
Selective and transient in vitro effects of heat shock on alveolar type II cell gene expression.
The American journal of physiology 1997;272(1 Pt 1):L132-8.
1996: Csaba Szabó; Hector R Wong; Andrew L Salzman
Pre-exposure to heat shock inhibits peroxynitrite-induced activation of poly(ADP) ribosyltransferase and protects against peroxynitrite cytotoxicity in J774 macrophages.
European journal of pharmacology 1996;315(2):221-6.