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Nora Wong

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Disorders

Physiology

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Publications

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Lili Li; Kajal Biswas; Laura Anne Habib; Sergey G Kuznetsov; Nancy Hamel; Tomas Kirchhoff; Nora Wong; Susan Armel; George Chong; Steven A Narod; Kathleen Claes; Kenneth Offit; Mark Robson; Stacey Stauffer; Shyam K Sharan; William D Foulkes
Functional redundancy of exon 12 of BRCA2 revealed by a comprehensive analysis of the c.6853A>G (p.I2285V) variant.
Marc Tischkowitz; Nancy Hamel; Marcelo A Carvalho; Gabriel Birrane; Aditi Soni; erik van beers; Simon A Joosse; Nora Wong; David Novak; Louise A Quenneville; Scott Grist; petra nederlof; David E Goldgar; Sean V Tavtigian; Alvaro Monteiro; John A A Ladias; William D Foulkes
Pathogenicity of the BRCA1 missense variant M1775K is determined by the disruption of the BRCT phosphopeptide-binding pocket: a multi-modal approach.
Marc Tischkowitz; Bing Xia; Nelly Sabbaghian; Jorge S Reis-Filho; Nancy Hamel; Guilan Li; erik van beers; Lili Li; Tayma Khalil; Louise A Quenneville; Atilla Omeroglu; Aletta Poll; Pierre Lepage; Nora Wong; petra nederlof; Alan Ashworth; Patricia N Tonin; Steven A Narod; David M Livingston; William D Foulkes
Analysis of PALB2/FANCN-associated breast cancer families.

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All Publications

2009: Lili Li; Kajal Biswas; Laura Anne Habib; Sergey G Kuznetsov; Nancy Hamel; Tomas Kirchhoff; Nora Wong; Susan Armel; George Chong; Steven A Narod; Kathleen Claes; Kenneth Offit; Mark Robson; Stacey Stauffer; Shyam K Sharan; William D Foulkes
Functional redundancy of exon 12 of BRCA2 revealed by a comprehensive analysis of the c.6853A>G (p.I2285V) variant.
Human mutation 2009;30(11):1543-50.
2008: Marc Tischkowitz; Nancy Hamel; Marcelo A Carvalho; Gabriel Birrane; Aditi Soni; erik van beers; Simon A Joosse; Nora Wong; David Novak; Louise A Quenneville; Scott Grist; petra nederlof; David E Goldgar; Sean V Tavtigian; Alvaro Monteiro; John A A Ladias; William D Foulkes
Pathogenicity of the BRCA1 missense variant M1775K is determined by the disruption of the BRCT phosphopeptide-binding pocket: a multi-modal approach.
European journal of human genetics : EJHG 2008;16(7):820-32.
2007: Marc Tischkowitz; Bing Xia; Nelly Sabbaghian; Jorge S Reis-Filho; Nancy Hamel; Guilan Li; erik van beers; Lili Li; Tayma Khalil; Louise A Quenneville; Atilla Omeroglu; Aletta Poll; Pierre Lepage; Nora Wong; petra nederlof; Alan Ashworth; Patricia N Tonin; Steven A Narod; David M Livingston; William D Foulkes
Analysis of PALB2/FANCN-associated breast cancer families.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(16):6788-93.
2007: Nancy Hamel; Nora Wong; Lesley Alpert; Maria Galvez; William D Foulkes
Mixed ovarian germ cell tumor in a BRCA2 mutation carrier.
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists 2007;26(2):160-4.
2007: Munir Al Refae; Nora Wong; François Patenaude; Louis R Bégin; William D Foulkes
Hereditary leiomyomatosis and renal cell cancer: an unusual and aggressive form of hereditary renal carcinoma.
Nature clinical practice. Oncology 2007;4(4):256-61.
2006: Susan McVety; Lili Li; Isabelle Thiffault; Philip H Gordon; Elizabeth MacNamara; Nora Wong; Karlene Australie; Lidia Kasprzak; George Chong; William D Foulkes
The value of multi-modal gene screening in HNPCC in Quebec: three mutations in mismatch repair genes that would have not been correctly identified by genomic DNA sequencing alone.
Familial cancer 2006;5(1):21-8.
2005: Susan McVety; Rami Younan; Lili Li; Philip H Gordon; Nora Wong; William D Foulkes; George Chong
Novel genomic insertion-- deletion in MLH1: possible mechanistic role for non-homologous end-joining DNA repair.
Clinical genetics 2005;68(3):234-8.
2005: Jarle Arnes; Jean-Sebastien Brunet; Ingunn M Stefansson; Louis R Bégin; Nora Wong; Pierre O Chappuis; Lars A Akslen; William D Foulkes
Placental cadherin and the basal epithelial phenotype of BRCA1-related breast cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(11):4003-11.
2005: Pierre O Chappuis; E Donato; John R Goffin; Nora Wong; Louis R Bégin; Linda Kapusta; Jean-Sebastien Brunet; P Porter; William D Foulkes
Cyclin E expression in breast cancer: predicting germline BRCA1 mutations, prognosis and response to treatment.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2005;16(5):735-42.
2004: Isabelle Thiffault; William D Foulkes; Victoria A Marcus; David Farber; Lidia Kasprzak; Elizabeth MacNamara; Nora Wong; Pierre Hutter; Paolo Radice; Lucio Bertario; George Chong
Putative common origin of two MLH1 mutations in Italian-Quebec hereditary non-polyposis colorectal cancer families.
Clinical genetics 2004;66(2):137-43.
2004: William D Foulkes; Jean-Sebastien Brunet; Ingunn M Stefansson; Oddbjørn Straume; Pierre O Chappuis; Louis R Bégin; Nancy Hamel; John R Goffin; Nora Wong; Michel Trudel; Linda Kapusta; Peggy Porter; Lars A Akslen
The prognostic implication of the basal-like (cyclin E high/p27 low/p53+/glomeruloid-microvascular-proliferation+) phenotype of BRCA1-related breast cancer.
Cancer research 2004;64(3):830-5.
2004: Mark Robson; Pierre O Chappuis; Jaya M Satagopan; Nora Wong; Jeff Boyd; John R Goffin; Clifford Hudis; David Roberge; Larry Norton; Louis R Bégin; Kenneth Offit; William D Foulkes
A combined analysis of outcome following breast cancer: differences in survival based on BRCA1/BRCA2 mutation status and administration of adjuvant treatment.
Breast cancer research : BCR 2004;6(1):R8-R17.
2003: William D Foulkes; Ingunn M Stefansson; Pierre O Chappuis; Louis R Bégin; John R Goffin; Nora Wong; Michel Trudel; Lars A Akslen
Germline BRCA1 mutations and a basal epithelial phenotype in breast cancer.
Journal of the National Cancer Institute 2003;95(19):1482-5.
2003: John R Goffin; Oddbjørn Straume; Pierre O Chappuis; Jean-Sebastien Brunet; Louis R Bégin; Nancy Hamel; Nora Wong; Lars A Akslen; William D Foulkes
Glomeruloid microvascular proliferation is associated with p53 expression, germline BRCA1 mutations and an adverse outcome following breast cancer.
British journal of cancer 2003;89(6):1031-4.
2003: John R Goffin; Pierre O Chappuis; Louis R Bégin; Nora Wong; Jean-Sebastien Brunet; Nancy Hamel; Ann-Josée Paradis; Jeff Boyd; William D Foulkes
Impact of germline BRCA1 mutations and overexpression of p53 on prognosis and response to treatment following breast carcinoma: 10-year follow up data.
Cancer 2003;97(3):527-36.
2002: William D Foulkes; John R Goffin; Jean-Sebastien Brunet; Louis R Bégin; Nora Wong; Pierre O Chappuis
Tamoxifen may be an effective adjuvant treatment for BRCA1-related breast cancer irrespective of estrogen receptor status.
Journal of the National Cancer Institute 2002;94(19):1504-6.
2002: Carol Cremin; Nora Wong; Karen Buzaglo; Ann-Josée Paradis; William D Foulkes
Nonovarian pelvic cancers in BRCA1/2 mutation carriers and the BRCAPRO statistical model.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2002;20(18):3936; author reply 3936-7.
2002: Pierre O Chappuis; John R Goffin; Nora Wong; C Perret; P Ghadirian; P N Tonin; William D Foulkes
A significant response to neoadjuvant chemotherapy in BRCA1/2 related breast cancer.
Journal of medical genetics 2002;39(8):608-10.
2002: William D Foulkes; Jean-Sebastien Brunet; Nora Wong; John R Goffin; Pierre O Chappuis
Change in the penetrance of founder BRCA1/2 mutations? A retrospective cohort study.
Journal of medical genetics 2002;39(6):407-9.
2002: Anne Andermann; Isabelle Thiffault; Nora Wong; Philip Gordon; Elizabeth MacNamara; George Chong; William D Foulkes
Multimodal molecular screening is required to improve the sensitivity of MLH1 and MSH2 mutation analysis.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2002;20(6):1705-7.
2002: Ziqiang Yuan; Bruce Gottlieb; Lenore K Beitel; Nora Wong; Philip H Gordon; Qing Wang; Alain Puisieux; William D Foulkes; Mark Trifiro
Polymorphisms and HNPCC: PMS2-MLH1 protein interactions diminished by single nucleotide polymorphisms.
Human mutation 2002;19(2):108-13.
2001: John R Goffin; Pierre O Chappuis; Nora Wong; William D Foulkes
Re: Magnetic resonance imaging and mammography in women with a hereditary risk of breast cancer.
Journal of the National Cancer Institute 2001;93(22):1754-5.
2001: R Rabelo; William D Foulkes; Philip H Gordon; Nora Wong; Ziqiang Yuan; Elizabeth MacNamara; George Chong; Leonard Pinsky; Dana Lasko
Role of molecular diagnostic testing in familial adenomatous polyposis and hereditary nonpolyposis colorectal cancer families.
Diseases of the colon and rectum 2001;44(3):437-46.
2001: Nora Wong; Dana Lasko; R Rabelo; Leonard Pinsky; Philip H Gordon; William D Foulkes
Genetic counseling and interpretation of genetic tests in familial adenomatous polyposis and hereditary nonpolyposis colorectal cancer.
Diseases of the colon and rectum 2001;44(2):271-9.
2000: Pierre O Chappuis; Linda Kapusta; Louis R Bégin; Nora Wong; Jean-Sebastien Brunet; Steven A Narod; Joyce M Slingerland; William D Foulkes
Germline BRCA1/2 mutations and p27(Kip1) protein levels independently predict outcome after breast cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2000;18(24):4045-52.
2000: William D Foulkes; Pierre O Chappuis; Nora Wong; Jean-Sebastien Brunet; Danny Vesprini; F Rozen; Ziqiang Yuan; MN Pollak; G Kuperstein; Steven A Narod; Louis R Bégin
Primary node negative breast cancer in BRCA1 mutation carriers has a poor outcome.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2000;11(3):307-13.
1999: Ziqiang Yuan; Louis R Bégin; Nora Wong; Jean-Sebastien Brunet; Mark Trifiro; Philip H Gordon; Leonard Pinsky; William D Foulkes
The effect of the I1307K APC polymorphism on the clinicopathological features and natural history of breast cancer.
British journal of cancer 1999;81(5):850-4.
1999: Ziqiang Yuan; Nora Wong; William D Foulkes; L Alpert; F Manganaro; Corinne Andreutti-Zaugg; Richard D Iggo; K Anthony; ET Hsieh; Mark Redston; Leonard Pinsky; Mark Trifiro; Philip H Gordon; Dana Lasko
A missense mutation in both hMSH2 and APC in an Ashkenazi Jewish HNPCC kindred: implications for clinical screening.
Journal of medical genetics 1999;36(10):790-3.
1998: William D Foulkes; Nora Wong; Jean-Sebastien Brunet; Steven A Narod
BRCA mutations and survival in breast cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1998;16(9):3206-8.
1998: Mark Redston; Katherine L Nathanson; Ziqiang Yuan; Susan L Neuhausen; Jaya M Satagopan; Nora Wong; D Yang; D Nafa; JL Abrahamson; Hilmi Ozcelik; Danielle Antin-Ozerkis; Irene L Andrulis; M Daly; Leonard Pinsky; Deborah Schrag; S Gallinger; M Kaback; Mary-Claire King; T Woodage; Lawrence C Brody; A Godwin; Ellen Warner; Barbara Weber; William D Foulkes; Kenneth Offit
The APCI1307K allele and breast cancer risk.
Nature genetics 1998;20(1):13-4.
1998: William D Foulkes; Nora Wong; F Rozen; Jean-Sebastien Brunet; Steven A Narod
Survival of patients with breast cancer and BRCA1 mutations.
Lancet 1998;351(9112):1359-60.
1997: William D Foulkes; Nora Wong; Jean-Sebastien Brunet; Louis R Bégin; J C Zhang; J J Martinez; F Rozen; Patricia N Tonin; Steven A Narod; S E Karp; MN Pollak
Germ-line BRCA1 mutation is an adverse prognostic factor in Ashkenazi Jewish women with breast cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 1997;3(12 Pt 1):2465-9.