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Peter T-H Wong

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Yan-Ying Liu; Bhushan Vijay Nagpure; Peter T-H Wong; Jin-Song Bian
Hydrogen sulfide protects SH-SY5Y neuronal cells against d-galactose induced cell injury by suppression of advanced glycation end products formation and oxidative stress.
Kay-Siong Ng; Peter T-H Wong; How-Wing Leung; Chian-Ming Low
Cleavage of the NR2B subunit amino terminus of N-methyl-D-aspartate (NMDA) receptor by tissue plasminogen activator: identification of the cleavage site and characterization of ifenprodil and glycine affinities on truncated NMDA receptor.
Yi-Hong Liu; Ming Lu; George D Webb; Peter T-H Wong; Li-Fang Hu; Jin-Song Bian
Hydrogen sulfide in the mammalian cardiovascular system.

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All Publications

2013: Yan-Ying Liu; Bhushan Vijay Nagpure; Peter T-H Wong; Jin-Song Bian
Hydrogen sulfide protects SH-SY5Y neuronal cells against d-galactose induced cell injury by suppression of advanced glycation end products formation and oxidative stress.
Neurochemistry international 2013;62(5):603-9.
2012: Kay-Siong Ng; Peter T-H Wong; How-Wing Leung; Chian-Ming Low
Cleavage of the NR2B subunit amino terminus of N-methyl-D-aspartate (NMDA) receptor by tissue plasminogen activator: identification of the cleavage site and characterization of ifenprodil and glycine affinities on truncated NMDA receptor.
The Journal of biological chemistry 2012;287(30):25520-9.
2012: Yi-Hong Liu; Ming Lu; George D Webb; Peter T-H Wong; Li-Fang Hu; Jin-Song Bian
Hydrogen sulfide in the mammalian cardiovascular system.
Antioxidants & redox signaling 2012;17(1):141-85.
2012: Yuan Sheng; Gordon K Wilcock; Peter T-H Wong; Christopher P Chen; Margaret Esiri; Jasinda H Lee; Andrew D Medhurst; Mitchell K P Lai
Preservation of cortical histamine H3 receptors in ischemic vascular and mixed dementias.
Journal of the neurological sciences 2012;315(1-2):110-4.
2011: Nur-Ezan Mohamed; A David Smith; Michelle G Tan; Gordon K Wilcock; Peter T-H Wong; Yi Zhao; Christopher P Chen; Margaret M Esiri; Jasinda H Lee; Mitchell K P Lai
Upregulation of AMPA receptor GluR2 (GluA2) subunits in subcortical ischemic vascular dementia is repressed in the presence of Alzheimer's disease.
Neurochemistry international 2011;58(7):820-5.
2011: Hong Wang; Jachim Spiess; Peter T-H Wong; Yi-Zhun Zhu
Blockade of CRF1 and CCK2 receptors attenuated the elevated anxiety-like behavior induced by immobilization stress.
Pharmacology, biochemistry, and behavior 2011;98(3):362-8.
2011: Mitchell K P Lai; Shirley W Tsang; Margaret M Esiri; Paul T Francis; Peter T-H Wong; Christopher P Chen
Differential involvement of hippocampal serotonin1A receptors and re-uptake sites in non-cognitive behaviors of Alzheimer's disease.
Psychopharmacology 2011;213(2-3):431-9.
2010: Jasinda H Lee; Grzegorz Agacinski; Jonathan H Williams; Gordon K Wilcock; Margaret M Esiri; Paul T Francis; Peter T-H Wong; Christopher P Chen; Mitchell K P Lai
Intact cannabinoid CB1 receptors in the Alzheimer's disease cortex.
Neurochemistry international 2010;57(8):985-9.
2010: Shirley W Y Tsang; Janet Keene; Tony Hope; Ian Spence; Paul T Francis; Peter T-H Wong; Christopher P Chen; Mitchell Lai
A serotoninergic basis for hyperphagic eating changes in Alzheimer's disease.
Journal of the neurological sciences 2010;288(1-2):151-5.
2010: Boon Hian Tan; Peter T-H Wong; Jin-Song Bian
Hydrogen sulfide: a novel signaling molecule in the central nervous system.
Neurochemistry international 2010;56(1):3-10.
2009: Fransisca Indraswari; Peter T-H Wong; Eric Yap; Yee-Kong NG; S Thameem Dheen
Upregulation of Dpysl2 and Spna2 gene expression in the rat brain after ischemic stroke.
Neurochemistry international 2009;55(4):235-42.
2008: Shirley W Y Tsang; Harry V Vinters; Jeffrey L Cummings; Peter T-H Wong; Christopher P L-H Chen; Mitchell Lai
Alterations in NMDA receptor subunit densities and ligand binding to glycine recognition sites are associated with chronic anxiety in Alzheimer's disease.
Neurobiology of aging 2008;29(10):1524-32.
2008: Shirley W Y Tsang; Paul T Francis; Margaret M Esiri; Peter T-H Wong; C P L-H Chen; Mitchell Lai
Loss of [3H]4-DAMP binding to muscarinic receptors in the orbitofrontal cortex of Alzheimer's disease patients with psychosis.
Psychopharmacology 2008;198(2):251-9.
2008: Kun Qu; S W Lee; Jin-Song Bian; Chian-Ming Low; Peter T-H Wong
Hydrogen sulfide: neurochemistry and neurobiology.
Neurochemistry international 2008;52(1-2):155-65.
2007: Nandhakishore Rajagopalan; Yuh Fen Pung; Yi-Zhun Zhu; Peter T-H Wong; Prakash P Kumar; R Manjunatha Kini
Beta-cardiotoxin: a new three-finger toxin from Ophiophagus hannah (king cobra) venom with beta-blocker activity.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007;21(13):3685-95.
2007: Shirley W Y Tsang; Justine Pomakian; Gad A Marshall; Harry V Vinters; Jeffrey L Cummings; Christopher P L-H Chen; Peter T-H Wong; Mitchell Lai
Disrupted muscarinic M1 receptor signaling correlates with loss of protein kinase C activity and glutamatergic deficit in Alzheimer's disease.
Neurobiology of aging 2007;28(9):1381-7.
2007: Wai Kit Chan; Peter T-H Wong; Fwu-Shan Sheu
Frontal cortical alpha7 and alpha4beta2 nicotinic acetylcholine receptors in working and reference memory.
Neuropharmacology 2007;52(8):1641-9.
2007: A Chen; Wupeng LIAO; Q Lu; W S Fred Wong; Peter T-H Wong
Upregulation of dihydropyrimidinase-related protein 2, spectrin alpha II chain, heat shock cognate protein 70 pseudogene 1 and tropomodulin 2 after focal cerebral ischemia in rats--a proteomics approach.
Neurochemistry international 2007;50(7-8):1078-86.
2007: Li-Fang Hu; Peter T-H Wong; Philip K Moore; Jin-Song Bian
Hydrogen sulfide attenuates lipopolysaccharide-induced inflammation by inhibition of p38 mitogen-activated protein kinase in microglia.
Journal of neurochemistry 2007;100(4):1121-8.
2006: Qing Wang; Xian Nan Tang; Lingzhi Wang; Midori A Yenari; Weihai Ying; Boon Cher Goh; How-Sung Lee; Einar Wilder-Smith; Peter T-H Wong
Effects of high dose of simvastatin on levels of dopamine and its reuptake in prefrontal cortex and striatum among SD rats.
Neuroscience letters 2006;408(3):189-93.
2006: Eng-Tat Ang; Gavin Dawe; Peter T-H Wong; Shabbir M Moochhala; Yee-Kong NG
Alterations in spatial learning and memory after forced exercise.
Brain research 2006;1113(1):186-93.
2006: Shirley W Y Tsang; Mitchell Lai; Sara Kirvell; Paul T Francis; Margaret M Esiri; Tony Hope; Christopher P L-H Chen; Peter T-H Wong
Impaired coupling of muscarinic M1 receptors to G-proteins in the neocortex is associated with severity of dementia in Alzheimer's disease.
Neurobiology of aging 2006;27(9):1216-23.
2006: Shiau Wei Lee; Ye-Shi Hu; Li-Fang Hu; Qing Lu; Gavin Dawe; Philip K Moore; Peter T-H Wong; Jin-Song Bian
Hydrogen sulphide regulates calcium homeostasis in microglial cells.
Glia 2006;54(2):116-24.
2006: Mitchell Lai; Shirley W Y Tsang; Monica Garcia-Alloza; Stephen L Minger; Nicoll James; Margaret M Esiri; Peter T-H Wong; Christopher P L-H Chen; María J Ramírez; Paul T Francis
Selective effects of the APOE epsilon4 allele on presynaptic cholinergic markers in the neocortex of Alzheimer's disease.
Neurobiology of disease 2006;22(3):555-61.
2006: Kun Qu; Christopher P L-H Chen; Barry Halliwell; Philip K Moore; Peter T-H Wong
Hydrogen sulfide is a mediator of cerebral ischemic damage.
Stroke; a journal of cerebral circulation 2006;37(3):889-93.
2006: Peter T-H Wong; Kun Qu; Ghislain N Chimon; Alvin B H Seah; Hui Meng Chang; Meng-Cheong Wong; Yee-Kong NG; Helmut Rumpel; Barry Halliwell; Christopher P L-H Chen
High plasma cyst(e)ine level may indicate poor clinical outcome in patients with acute stroke: possible involvement of hydrogen sulfide.
Journal of neuropathology and experimental neurology 2006;65(2):109-15.
2006: Xuejing Liu; Tat-Leang Lee; Peter T-H Wong
Cyclooxygenase-1 inhibition shortens the duration of diazepam-induced loss of righting reflex in mice.
Anesthesia and analgesia 2006;102(1):135-40.
2005: Qing Lu; Yi-Zhun Zhu; Peter T-H Wong
Neuroprotective effects of candesartan against cerebral ischemia in spontaneously hypertensive rats.
Neuroreport 2005;16(17):1963-7.
2005: Qing Wang; P H Wang; Craig S McLachlan; Peter T-H Wong
Simvastatin reverses the downregulation of dopamine D1 and D2 receptor expression in the prefrontal cortex of 6-hydroxydopamine-induced Parkinsonian rats.
Brain research 2005;1045(1-2):229-33.
2005: Qing Wang; Wee Lee Ting; Hongyuan Yang; Peter T-H Wong
High doses of simvastatin upregulate dopamine D1 and D2 receptor expression in the rat prefrontal cortex: possible involvement of endothelial nitric oxide synthase.
British journal of pharmacology 2005;144(7):933-9.
2005: Yuh Fen Pung; Peter T-H Wong; Prakash P Kumar; Wayne C Hodgson; R Manjunatha Kini
Ohanin, a novel protein from king cobra venom, induces hypolocomotion and hyperalgesia in mice.
The Journal of biological chemistry 2005;280(13):13137-47.
2005: Craig S McLachlan; Wendy Chen-Nee Chua; Peter T-H Wong; Ti Lian Kah; Christopher Chen; Reida El Oakley
Homocysteine is positively associated with cytokine IL-18 plasma levels in coronary artery bypass surgery patients.
BioFactors (Oxford, England) 2005;23(2):69-73.
2005: Hong Wang; Peter T-H Wong; Joachim Spiess; Yi-Zhun Zhu
Cholecystokinin-2 (CCK2) receptor-mediated anxiety-like behaviors in rats.
Neuroscience and biobehavioral reviews 2005;29(8):1361-73.
2004: Qing Lu; Yi-Zhun Zhu; Peter T-H Wong
Angiotensin receptor gene expression in candesartan mediated neuroprotection.
Neuroreport 2004;15(17):2643-6.
2004: JM Farook; Yi-Zhun Zhu; Qing Wang; Shabbir M Moochhala; L Lee; Peter T-H Wong
Analysis of strain difference in behavior to Cholecystokinin (CCK) receptor mediated drugs in PVG hooded and Sprague-Dawley rats using elevated plus-maze test apparatus.
Neuroscience letters 2004;358(3):215-9.
2004: Jeyanthi Chinnappa Thenmozhiyal; Peter T-H Wong; Wai-Keung Chui
Anticonvulsant activity of phenylmethylenehydantoins: a structure-activity relationship study.
Journal of medicinal chemistry 2004;47(6):1527-35.
2004: JM Farook; C S McLachlan; Yi-Zhun Zhu; L Lee; Shabbir M Moochhala; Peter T-H Wong
The CCK2 agonist BC264 reverses freezing behavior habituation in PVG hooded rats on repeated exposures to a cat.
Neuroscience letters 2004;355(3):205-8.
2004: JM Farook; Qing Wang; Shabbir M Moochhala; Z Y Zhu; L Lee; Peter T-H Wong
Distinct regions of periaqueductal gray (PAG) are involved in freezing behavior in hooded PVG rats on the cat-freezing test apparatus.
Neuroscience letters 2004;354(2):139-42.
2004: Eng-Tat Ang; Peter T-H Wong; Shabbir M Moochhala; Yee-Kong NG
Cytokine changes in the horizontal diagonal band of Broca in the septum after running and stroke: a correlation to glial activation.
Neuroscience 2004;129(2):337-47.
2003: Shirley W Y Tsang; Mitchell Lai; Paul T Francis; Peter T-H Wong; Ian Spence; Margaret M Esiri; Janet Keene; Tony Hope; Christopher P L-H Chen
Serotonin transporters are preserved in the neocortex of anxious Alzheimer's disease patients.
Neuroreport 2003;14(10):1297-300.
2003: Hong Wang; Yi-Zhun Zhu; JM Farook; Shabbir M Moochhala; Ai Ling Teo; L K H Lee; Peter T-H Wong
Genetic variations in CCK2 receptor in PVG hooded and Sprague-Dawley rats and its mRNA expression on cat exposure.
Behavioral neuroscience 2003;117(2):385-90.
2003: Hong Wang; Yi-Zhun Zhu; Peter T-H Wong; JM Farook; Ai Ling Teo; L K H Lee; Shabbir M Moochhala
cDNA microarray analysis of gene expression in anxious PVG and SD rats after cat-freezing test.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 2003;149(4):413-21.
2003: Eng-Tat Ang; Peter T-H Wong; Shabbir M Moochhala; Yee-Kong NG
Neuroprotection associated with running: is it a result of increased endogenous neurotrophic factors?
Neuroscience 2003;118(2):335-45.
2002: Mei Xu; Yee-Kong NG; Peter T-H Wong
Visualization and distribution of neuronal nitric oxide synthase-containing neurons.
Methods in enzymology 2002;359():424-32.
2002: L-S Loo; Yee-Kong NG; Yi-Zhun Zhu; H-S Lee; Peter T-H Wong
Cortical expression of endothelin receptor subtypes A and B following middle cerebral artery occlusion in rats.
Neuroscience 2002;112(4):993-1000.
2001: X Zhu; S Jin; Yee-Kong NG; W L Lee; Peter T-H Wong
Positive and negative modulation by AMPA- and kainate-receptors of striatal kainate injection-induced neuronal loss in rat forebrain.
Brain research 2001;922(2):293-8.
2001: JM Farook; Yi-Zhun Zhu; Hong Wang; Shabbir M Moochhala; L Lee; Peter T-H Wong
Strain differences in freezing behavior of PVG hooded and Sprague-Dawley rats: differential cortical expression of cholecystokinin2 receptors.
Neuroreport 2001;12(12):2717-20.
2000: S Jin; J Yang; W L Lee; Peter T-H Wong
Crucial role of kainate receptors in mediating striatal kainate injection-induced decrease in acetylcholine M(1) receptor binding in rat forebrain.
Brain research 2000;882(1-2):128-38.
2000: Yi-Zhun Zhu; Ghislain N Chimon; Y C Zhu; Qing Lu; B Li; HZ Hu; Eu Hian Yap; H S Lee; Peter T-H Wong
Expression of angiotensin II AT2 receptor in the acute phase of stroke in rats.
Neuroreport 2000;11(6):1191-4.
2000: S N Li; Peter T-H Wong
The adenosine receptor agonist, APNEA, increases calcium influx into rat cortical synaptosomes through N-type channels associated with A2a receptors.
Neurochemical research 2000;25(4):457-9.
1999: Yee-Kong NG; YD Xue; Peter T-H Wong
Different distributions of nitric oxide synthase-containing neurons in the mouse and rat hypothalamus.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 1999;3(5):383-92.
1999: N K Ng; H S Lee; Peter T-H Wong
Regulation of striatal dopamine release through 5-HT1 and 5-HT2 receptors.
Journal of neuroscience research 1999;55(5):600-7.
1998: Fai Tsang; Alan H M Koh; Wee Lee Ting; Peter T-H Wong; W S Fred Wong
Effects of mitogen-activated protein kinase kinase inhibitor PD 098059 on antigen challenge of guinea-pig airways in vitro.
British journal of pharmacology 1998;125(1):61-8.
1998: Ghislain N Chimon; Peter T-H Wong
Ischemic tolerance and lipid peroxidation in the brain.
Neuroreport 1998;9(10):2269-72.
1997: YD Xue; Peter T-H Wong; Seng-Kee Leong
Nitric oxide synthase-, N-methyl-D-aspartate receptor-, glutamate- and aspartate-immunoreactive neurons in the mouse arcuate nucleus: effects of neonatal treatment with monosodium glutamate.
Acta neuropathologica 1997;94(6):572-82.
1997: W S Fred Wong; David S-Q Koh; Alan H M Koh; Wee Lee Ting; Peter T-H Wong
Effects of tyrosine kinase inhibitors on antigen challenge of guinea pig lung in vitro.
The Journal of pharmacology and experimental therapeutics 1997;283(1):131-7.
1997: Peter T-H Wong; L H Neo; W L Teo; H Feng; YD Xue; W H Loke
Deficits in water escape performance and alterations in hippocampal cholinergic mechanisms associated with neonatal monosodium glutamate treatment in mice.
Pharmacology, biochemistry, and behavior 1997;57(1-2):383-8.
1996: Yi He; Patricia Soo-Ping Thong; Timothy Lee; Seng-Kee Leong; CY Shi; Peter T-H Wong; S Y Yuan; Frank Watt
Increased iron in the substantia nigra of 6-OHDA induced parkinsonian rats: a nuclear microscopy study.
Brain research 1996;735(1):149-53.
1995: X C Pu; Peter T-H Wong; Ponnampalam Gopalakrishnakone
A novel analgesic toxin (hannalgesin) from the venom of king cobra (Ophiophagus hannah).
Toxicon : official journal of the International Society on Toxinology 1995;33(11):1425-31.
1995: Peter T-H Wong; Runsheng Ruan; Seng-Kee Leong; Kian Hian Yeoh
Compression of the facial nerve caused increased nitric oxide synthase activity in the facial motor nucleus.
Neuroscience 1995;67(3):697-702.
1995: Peter T-H Wong; H Feng; W L Teo
Interaction of the dopaminergic and serotonergic systems in the rat striatum: effects of selective antagonists and uptake inhibitors.
Neuroscience research 1995;23(1):115-9.
1994: Matthew C E Gwee; L S Cheah; Ponnampalam Gopalakrishnakone; Peter T-H Wong
Prejunctional action of the venom from the Indian red scorpion Mesobuthus tamulus on adrenergic transmission in vitro.
Toxicon : official journal of the International Society on Toxinology 1994;32(2):201-9.
1993: Peter T-H Wong; W L Teo; T Lee
A microdialysis study on striatal dopamine, 5-HT and metabolites in conscious rats after various treatments: evidence for extravesicular release of dopamine.
Neuroreport 1993;5(1):53-6.
1993: Matthew C E Gwee; Peter T-H Wong; Ponnampalam Gopalakrishnakone; L S Cheah; K S Low
The black scorpion Heterometrus longimanus: pharmacological and biochemical investigation of the venom.
Toxicon : official journal of the International Society on Toxinology 1993;31(10):1305-14.
1991: Peter T-H Wong; W L Teo
Localization of the specific binding sites of [(3)H]tryptophan in rat brain.
Neurochemistry international 1991;18(3):353-6.
1989: Peter T-H Wong; H S Lee; C H Tan; W L Teo
Specific [(3)H]tryptophan binding sites in rat brain.
Neurochemistry international 1989;15(1):25-31.
1985: Peter T-H Wong
Rat brain aspartate ?-decarboxylase. A comparative study with the liver enzyme.
Neurochemistry international 1985;7(2):351-5.
1985: Peter T-H Wong; W L Teo; S F Leong
Some characteristics of ?(1)-pyrroline-5-carboxylate dehydrogenase in rat cerebellum.
Neurochemistry international 1985;7(1):45-9.