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Susan Wonnacott

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Hayley M Bennett; Kate M Harper; Andrew Ken Jones; Kristin Lees; David B Sattelle; Susan Wonnacott; Adrian J Wolstenholme
Xenopus laevis RIC-3 enhances the functional expression of the C. elegans homomeric nicotinic receptor, ACR-16, in Xenopus oocytes.
Alexandra Kennett; David J Heal; Susan Wonnacott
Pharmacological differences between rat frontal cortex and hippocampus in the nicotinic modulation of noradrenaline release implicate distinct receptor subtypes.
Susan K Glendinning; David B Sattelle; Steven D Buckingham; Susan Wonnacott; Adrian J Wolstenholme
Glutamate-gated chloride channels of Haemonchus contortus restore drug sensitivity to ivermectin resistant Caenorhabditis elegans.

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2012: Hayley M Bennett; Kate M Harper; Andrew Ken Jones; Kristin Lees; David B Sattelle; Susan Wonnacott; Adrian J Wolstenholme
Xenopus laevis RIC-3 enhances the functional expression of the C. elegans homomeric nicotinic receptor, ACR-16, in Xenopus oocytes.
Journal of neurochemistry 2012;123(6):911-8.
2012: Alexandra Kennett; David J Heal; Susan Wonnacott
Pharmacological differences between rat frontal cortex and hippocampus in the nicotinic modulation of noradrenaline release implicate distinct receptor subtypes.
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2012;14(11):1339-45.
2011: Susan K Glendinning; David B Sattelle; Steven D Buckingham; Susan Wonnacott; Adrian J Wolstenholme
Glutamate-gated chloride channels of Haemonchus contortus restore drug sensitivity to ivermectin resistant Caenorhabditis elegans.
PloS one 2011;6(7):e22390.
2010: Patricio Iturriaga-Vásquez; Annalisa Carbone; Olimpo García-Beltrán; Phil D Livingstone; Philip C Biggin; Bruce K Cassels; Susan Wonnacott; Gerald Zapata-Torres; Isabel Bermudez
Molecular determinants for competitive inhibition of alpha4beta2 nicotinic acetylcholine receptors.
Molecular pharmacology 2010;78(3):366-75.
2010: Neal Innocent; Nicholas Evans; Christopher Hille; Susan Wonnacott
Oligomerisation differentially affects the acute and chronic actions of amyloid-beta in vitro.
Neuropharmacology 2010;59(4-5):343-52.
2010: Juan Andrés Abin-Carriquiry; Margot Paulino Zunini; Bruce K Cassels; Susan Wonnacott; Federico Dajas
In silico characterization of cytisinoids docked into an acetylcholine binding protein.
Bioorganic & medicinal chemistry letters 2010;20(12):3683-7.
2010: J Andrés Abin-Carriquiry; Jessika Urbanavicius; Cecilia Scorza; Marcos Rebolledo-Fuentes; Susan Wonnacott; Bruce K Cassels; Federico Dajas
Increase in locomotor activity after acute administration of the nicotinic receptor agonist 3-bromocytisine in rats.
European journal of pharmacology 2010;634(1-3):89-94.
2010: Phil D Livingstone; Jane A Dickinson; Jayaraman Srinivasan; James N C Kew; Susan Wonnacott
Glutamate-dopamine crosstalk in the rat prefrontal cortex is modulated by Alpha7 nicotinic receptors and potentiated by PNU-120596.
Journal of molecular neuroscience : MN 2010;40(1-2):172-6.
2009: Phil D Livingstone; Susan Wonnacott
Nicotinic acetylcholine receptors and the ascending dopamine pathways.
Biochemical pharmacology 2009;78(7):744-55.
2009: DAVIDE QUARTA; Christopher G Naylor; Jacques Barik; Cathy Fernandes; Susan Wonnacott; Ian P Stolerman
Drug discrimination and neurochemical studies in alpha7 null mutant mice: tests for the role of nicotinic alpha7 receptors in dopamine release.
Psychopharmacology 2009;203(2):399-410.
2009: Phil D Livingstone; Jayaraman Srinivasan; James N C Kew; Lee A Dawson; Cecilia Gotti; Milena Moretti; Mohammed Shoaib; Susan Wonnacott
alpha7 and non-alpha7 nicotinic acetylcholine receptors modulate dopamine release in vitro and in vivo in the rat prefrontal cortex.
The European journal of neuroscience 2009;29(3):539-50.
2008: Neal Innocent; Phil D Livingstone; Arik Hone; Atsuko Kimura; Tracey Young; Paul Whiteaker; J Michael McIntosh; Susan Wonnacott
Alpha-conotoxin Arenatus IB[V11L,V16D] [corrected] is a potent and selective antagonist at rat and human native alpha7 nicotinic acetylcholine receptors.
The Journal of pharmacology and experimental therapeutics 2008;327(2):529-37.
2008: Jane A Dickinson; James N C Kew; Susan Wonnacott
Presynaptic alpha 7- and beta 2-containing nicotinic acetylcholine receptors modulate excitatory amino acid release from rat prefrontal cortex nerve terminals via distinct cellular mechanisms.
Molecular pharmacology 2008;74(2):348-59.
2008: J Andrés Abin-Carriquiry; Gustavo Costa; Jessika Urbanavicius; Bruce K Cassels; Marco Rebolledo-Fuentes; Susan Wonnacott; Federico Dajas
In vivo modulation of dopaminergic nigrostriatal pathways by cytisine derivatives: implications for Parkinson's Disease.
European journal of pharmacology 2008;589(1-3):80-4.
2008: Susan Wonnacott
Smoking cessation 2008.
IDrugs : the investigational drugs journal 2008;11(4):256-9.
2008: Katharine Hanrott; Tracey K Murray; Zeina Orfali; Mark Ward; Clare Finlay; Michael J O'Neill; Susan Wonnacott
Differential activation of PKC delta in the substantia nigra of rats following striatal or nigral 6-hydroxydopamine lesions.
The European journal of neuroscience 2008;27(5):1086-96.
2008: Susan Wonnacott
Gates and filters: unveiling the physiological roles of nicotinic acetylcholine receptors in dopaminergic transmission.
British journal of pharmacology 2008;153 Suppl 1():S2-4.
2007: Jennifer L Oliver; Ghazaleh Pashmi; Paul Barnett; Pascal Mettens; Ralph Biemans; Philippe Monteyne; Rémi Palmantier; Timothy Gallagher; Sharn Ramaya; Susan Wonnacott
Development of an anti-cotinine vaccine to potentiate nicotine-based smoking cessation strategies.
Vaccine 2007;25(42):7354-62.
2007: Nimish Sidhpura; Peter Redfern; Helen Rowley; David Heal; Susan Wonnacott
Comparison of the effects of bupropion and nicotine on locomotor activation and dopamine release in vivo.
Biochemical pharmacology 2007;74(8):1292-8.
2007: Jessika Urbanavicius; Margot Ferreira; Gustavo Costa; J Andrés Abin-Carriquiry; Susan Wonnacott; Federico Dajas
Nicotine induces tyrosine hydroxylase plasticity in the neurodegenerating striatum.
Journal of neurochemistry 2007;102(3):723-30.
2007: Nimish Sidhpura; Peter Redfern; Susan Wonnacott
Comparison of the effects of bupropion on nicotinic receptor-evoked [(3)H]dopamine release from rat striatal synaptosomes and slices.
European journal of pharmacology 2007;567(1-2):102-9.
2007: Jane A Dickinson; Katharine E Hanrott; M H Selina Mok; James N C Kew; Susan Wonnacott
Differential coupling of alpha7 and non-alpha7 nicotinic acetylcholine receptors to calcium-induced calcium release and voltage-operated calcium channels in PC12 cells.
Journal of neurochemistry 2007;100(4):1089-96.
2007: Saara Nuutinen; Jacques Barik; Ian W Jones; Susan Wonnacott
Differential effects of acute and chronic nicotine on Elk-1 in rat hippocampus.
Neuroreport 2007;18(2):121-6.
2006: Akira Kanakubo; Diane Gray; Neal Innocent; Susan Wonnacott; Timothy Gallagher
The synthesis and nicotinic binding activity of (+/-)-epiquinamide and (+/-)-C(1)-epiepiquinamide.
Bioorganic & medicinal chemistry letters 2006;16(17):4648-51.
2006: J Andrés Abin-Carriquiry; Merja H Voutilainen; Jacques Barik; Bruce K Cassels; Patricio Iturriaga-Vásquez; Isabel Bermudez; Claudia Durand; Federico Dajas; Susan Wonnacott
C3-halogenation of cytisine generates potent and efficacious nicotinic receptor agonists.
European journal of pharmacology 2006;536(1-2):1-11.
2006: Katharine Hanrott; Louise Gudmunsen; Michael J O'Neill; Susan Wonnacott
6-hydroxydopamine-induced apoptosis is mediated via extracellular auto-oxidation and caspase 3-dependent activation of protein kinase Cdelta.
The Journal of biological chemistry 2006;281(9):5373-82.
2006: Jacques Barik; Susan Wonnacott
Indirect modulation by alpha7 nicotinic acetylcholine receptors of noradrenaline release in rat hippocampal slices: interaction with glutamate and GABA systems and effect of nicotine withdrawal.
Molecular pharmacology 2006;69(2):618-28.
2006: Susan Wonnacott; Jacques Barik; Jane Dickinson; Ian W Jones
Nicotinic receptors modulate transmitter cross talk in the CNS: nicotinic modulation of transmitters.
Journal of molecular neuroscience : MN 2006;30(1-2):137-40.
2006: Ian W Jones; Adam Westmacott; Elcie Chan; Roy W Jones; Kelly T Dineley; Michael J O'Neill; Susan Wonnacott
Alpha7 nicotinic acetylcholine receptor expression in Alzheimer's disease: receptor densities in brain regions of the APP(SWE) mouse model and in human peripheral blood lymphocytes.
Journal of molecular neuroscience : MN 2006;30(1-2):83-4.
2005: Bruce K Cassels; Isabel Bermúdez; Federico Dajas; J Andrés Abin-Carriquiry; Susan Wonnacott
From ligand design to therapeutic efficacy: the challenge for nicotinic receptor research.
Drug discovery today 2005;10(23-24):1657-65.
2005: Jacques Barik; Federico Dajas-Bailador; Susan Wonnacott
Cellular responses to nicotinic receptor activation are decreased after prolonged exposure to galantamine in human neuroblastoma cells.
British journal of pharmacology 2005;145(8):1084-92.
2005: Stephen J Rousseau; Ian W Jones; Ian A Pullar; Susan Wonnacott
Presynaptic alpha7 and non-alpha7 nicotinic acetylcholine receptors modulate [3H]d-aspartate release from rat frontal cortex in vitro.
Neuropharmacology 2005;49(1):59-72.
2005: Ian W Jones; Susan Wonnacott
Why doesn't nicotinic ACh receptor immunoreactivity knock out?
Trends in neurosciences 2005;28(7):343-5.
2005: Susan Wonnacott; Nimish Sidhpura; David J K Balfour
Nicotine: from molecular mechanisms to behaviour.
Current opinion in pharmacology 2005;5(1):53-9.
2004: Ian W Jones; Susan Wonnacott
Precise localization of alpha7 nicotinic acetylcholine receptors on glutamatergic axon terminals in the rat ventral tegmental area.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(50):11244-52.
2004: Adrian J Mogg; Francis A Jones; Ian A Pullar; Christopher G V Sharples; Susan Wonnacott
Functional responses and subunit composition of presynaptic nicotinic receptor subtypes explored using the novel agonist 5-iodo-A-85380.
Neuropharmacology 2004;47(6):848-59.
2004: Annette Nicke; Susan Wonnacott; Richard J Lewis
Alpha-conotoxins as tools for the elucidation of structure and function of neuronal nicotinic acetylcholine receptor subtypes.
European journal of biochemistry / FEBS 2004;271(12):2305-19.
2004: Federico Dajas-Bailador; Susan Wonnacott
Nicotinic acetylcholine receptors and the regulation of neuronal signalling.
Trends in pharmacological sciences 2004;25(6):317-24.
2004: Ian W Jones; Jacques Barik; Michael J O'Neill; Susan Wonnacott
Alpha bungarotoxin-1.4 nm gold: a novel conjugate for visualising the precise subcellular distribution of alpha 7* nicotinic acetylcholine receptors.
Journal of neuroscience methods 2004;134(1):65-74.
2003: M V Hejmadi; Federico Dajas-Bailador; S M Barns; B Jones; Susan Wonnacott
Neuroprotection by nicotine against hypoxia-induced apoptosis in cortical cultures involves activation of multiple nicotinic acetylcholine receptor subtypes.
Molecular and cellular neurosciences 2003;24(3):779-86.
2003: Federico Dajas-Bailador; Kaisa Heimala; Susan Wonnacott
The allosteric potentiation of nicotinic acetylcholine receptors by galantamine is transduced into cellular responses in neurons: Ca2+ signals and neurotransmitter release.
Molecular pharmacology 2003;64(5):1217-26.
2003: Gunter Karig; Jonathan M Large; Christopher G V Sharples; Andrew Sutherland; Timothy Gallagher; Susan Wonnacott
Synthesis and nicotinic binding of novel phenyl derivatives of UB-165. Identifying factors associated with alpha7 selectivity.
Bioorganic & medicinal chemistry letters 2003;13(17):2825-8.
2003: Britta Hahn; Christopher G V Sharples; Susan Wonnacott; Mohammed Shoaib; Ian P Stolerman
Attentional effects of nicotinic agonists in rats.
Neuropharmacology 2003;44(8):1054-67.
2003: Andrew Sutherland; Timothy Gallagher; Christopher G V Sharples; Susan Wonnacott
Synthesis of two fluoro analogues of the nicotinic acetylcholine receptor agonist UB-165.
The Journal of organic chemistry 2003;68(6):2475-8.
2003: CE Richardson; J M Morgan; B Jasani; John T Green; John Rhodes; Geraint T Williams; J Lindstrom; Susan Wonnacott; S Peel; G A O Thomas
Effect of smoking and transdermal nicotine on colonic nicotinic acetylcholine receptors in ulcerative colitis.
QJM : monthly journal of the Association of Physicians 2003;96(1):57-65.
2002: Christopher G V Sharples; Gunter Karig; Graham L Simpson; James A Spencer; Emma Wright; Neil S Millar; Susan Wonnacott; Timothy Gallagher
Synthesis and pharmacological characterization of novel analogues of the nicotinic acetylcholine receptor agonist (+/-)-UB-165.
Journal of medicinal chemistry 2002;45(15):3235-45.
2002: Adrian J Mogg; Paul Whiteaker; J Michael McIntosh; Michael Marks; Allan C Collins; Susan Wonnacott
Methyllycaconitine is a potent antagonist of alpha-conotoxin-MII-sensitive presynaptic nicotinic acetylcholine receptors in rat striatum.
The Journal of pharmacology and experimental therapeutics 2002;302(1):197-204.
2002: Claudio Da Cunha; M E M Angelucci; Newton S Canteras; Susan Wonnacott; Reinaldo N Takahashi
The lesion of the rat substantia nigra pars compacta dopaminergic neurons as a model for Parkinson's disease memory disabilities.
Cellular and molecular neurobiology 2002;22(3):227-37.
2002: Federico Dajas-Bailador; Adrian J Mogg; Susan Wonnacott
Intracellular Ca2+ signals evoked by stimulation of nicotinic acetylcholine receptors in SH-SY5Y cells: contribution of voltage-operated Ca2+ channels and Ca2+ stores.
Journal of neurochemistry 2002;81(3):606-14.
2002: Federico Dajas-Bailador; L Soliakov; Susan Wonnacott
Nicotine activates the extracellular signal-regulated kinase 1/2 via the alpha7 nicotinic acetylcholine receptor and protein kinase A, in SH-SY5Y cells and hippocampal neurones.
Journal of neurochemistry 2002;80(3):520-30.
2002: Diana L Ridley; Jukka Pakkanen; Susan Wonnacott
Effects of chronic drug treatments on increases in intracellular calcium mediated by nicotinic acetylcholine receptors in SH-SY5Y cells.
British journal of pharmacology 2002;135(4):1051-9.
2001: Ian W Jones; J P Bolam; Susan Wonnacott
Presynaptic localisation of the nicotinic acetylcholine receptor beta2 subunit immunoreactivity in rat nigrostriatal dopaminergic neurones.
The Journal of comparative neurology 2001;439(2):235-47.
2001: D L Ridley; A Rogers; Susan Wonnacott
Differential effects of chronic drug treatment on alpha3* and alpha7 nicotinic receptor binding sites, in hippocampal neurones and SH-SY5Y cells.
British journal of pharmacology 2001;133(8):1286-95.
2001: CE Richardson; J M Morgan; B Jasani; John T Green; John Rhodes; Geraint T Williams; J Lindstrom; Susan Wonnacott; G A O Thomas; V Smith
Megacystis-microcolon-intestinal hypoperistalsis syndrome and the absence of the alpha3 nicotinic acetylcholine receptor subunit.
Gastroenterology 2001;121(2):350-7.
2001: RJ Lind; DJ Hardick; Ian S Blagbrough; BV Potter; Adrian J Wolstenholme; AR Davies; M S Clough; F G Earley; Stuart E Reynolds; Susan Wonnacott
[3H]-Methyllycaconitine: a high affinity radioligand that labels invertebrate nicotinic acetylcholine receptors.
Insect biochemistry and molecular biology 2001;31(6-7):533-42.
2001: L Soliakov; Susan Wonnacott
Involvement of protein kinase C in the presynaptic nicotinic modulation of [(3)H]-dopamine release from rat striatal synaptosomes..
British journal of pharmacology 2001;132(3):785-91.
2000: Federico Dajas-Bailador; P A Lima; Susan Wonnacott
The alpha7 nicotinic acetylcholine receptor subtype mediates nicotine protection against NMDA excitotoxicity in primary hippocampal cultures through a Ca(2+) dependent mechanism.
Neuropharmacology 2000;39(13):2799-807.
2000: SA Kaiser; Susan Wonnacott
alpha-bungarotoxin-sensitive nicotinic receptors indirectly modulate [(3)H]dopamine release in rat striatal slices via glutamate release.
Molecular pharmacology 2000;58(2):312-8.
2000: Christopher G V Sharples; SA Kaiser; L Soliakov; Michael J Marks; Allan C Collins; M Washburn; E Wright; J A Spencer; Timothy Gallagher; Paul Whiteaker; Susan Wonnacott
UB-165: a novel nicotinic agonist with subtype selectivity implicates the alpha4beta2* subtype in the modulation of dopamine release from rat striatal synaptosomes.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000;20(8):2783-91.
2000: Susan Wonnacott; SA Kaiser; Adrian J Mogg; L Soliakov; Ian W Jones
Presynaptic nicotinic receptors modulating dopamine release in the rat striatum.
European journal of pharmacology 2000;393(1-3):51-8.
1999: Paul Whiteaker; AR Davies; Michael J Marks; Ian S Blagbrough; BV Potter; Adrian J Wolstenholme; Allan C Collins; Susan Wonnacott
An autoradiographic study of the distribution of binding sites for the novel alpha7-selective nicotinic radioligand [3H]-methyllycaconitine in the mouse brain.
The European journal of neuroscience 1999;11(8):2689-96.
1999: AR Davies; DJ Hardick; Ian S Blagbrough; BV Potter; Adrian J Wolstenholme; Susan Wonnacott
Characterisation of the binding of [3H]methyllycaconitine: a new radioligand for labelling alpha 7-type neuronal nicotinic acetylcholine receptors.
Neuropharmacology 1999;38(5):679-90.
1998: Paul Whiteaker; Christopher G V Sharples; Susan Wonnacott
Agonist-induced up-regulation of alpha4beta2 nicotinic acetylcholine receptors in M10 cells: pharmacological and spatial definition.
Molecular pharmacology 1998;53(5):950-62.
1998: H M Eastham; RJ Lind; J L Eastlake; B S Clarke; P Towner; Stuart E Reynolds; Adrian J Wolstenholme; Susan Wonnacott
Characterization of a nicotinic acetylcholine receptor from the insect Manduca sexta.
The European journal of neuroscience 1998;10(3):879-89.
1998: SA Kaiser; L Soliakov; SC Harvey; Charles W Luetje; Susan Wonnacott
Differential inhibition by alpha-conotoxin-MII of the nicotinic stimulation of [3H]dopamine release from rat striatal synaptosomes and slices.
Journal of neurochemistry 1998;70(3):1069-76.
1997: Paul Whiteaker; Christopher G V Sharples; Susan Wonnacott
Pharmacology of nicotinic acetylcholine receptor (nAChR) upregulation in the transfected cell line, M10.
Biochemical Society transactions 1997;25(3):550S.
1997: AR Davies; DJ Hardick; Ian S Blagbrough; BV Potter; Adrian J Wolstenholme; Susan Wonnacott
Structure-activity studies of bicyclic and tricyclic analogues of methyllycaconitine.
Biochemical Society transactions 1997;25(3):545S.
1997: A T Rogers; Susan Wonnacott
Differential upregulation of alpha 7 and alpha 3 subunit-containing nicotinic acetylcholine receptors in rat hippocampal and PC12 cell cultures.
Biochemical Society transactions 1997;25(3):544S.
1997: D L Marshall; Peter Redfern; Susan Wonnacott
Presynaptic nicotinic modulation of dopamine release in the three ascending pathways studied by in vivo microdialysis: comparison of naive and chronic nicotine-treated rats.
Journal of neurochemistry 1997;68(4):1511-9.
1997: N Samuel; Susan Wonnacott; J Lindstrom; A H Futerman
Parallel increases in [alpha-125I]bungarotoxin binding and alpha 7 nicotinic subunit immunoreactivity during the development of rat hippocampal neurons in culture.
Neuroscience letters 1997;222(3):179-82.
1997: Susan Wonnacott
Presynaptic nicotinic ACh receptors.
Trends in neurosciences 1997;20(2):92-8.
1996: D J Hardick; Ian S Blagbrough; G Cooper; B V Potter; T Critchley; Susan Wonnacott
Nudicauline and elatine as potent norditerpenoid ligands at rat neuronal alpha-bungarotoxin binding sites: importance of the 2-(methylsuccinimido)benzoyl moiety for neuronal nicotinic acetylcholine receptor binding.
Journal of medicinal chemistry 1996;39(24):4860-6.
1996: G I Wilkie; P Hutson; J P Sullivan; Susan Wonnacott
Pharmacological characterization of a nicotinic autoreceptor in rat hippocampal synaptosomes.
Neurochemical research 1996;21(9):1141-8.
1996: L Soliakov; Susan Wonnacott
Voltage-sensitive Ca2+ channels involved in nicotinic receptor-mediated [3H]dopamine release from rat striatal synaptosomes.
Journal of neurochemistry 1996;67(1):163-70.
1996: D Marshall; L Soliakov; Peter Redfern; Susan Wonnacott
Tetrodotoxin-sensitivity of nicotine-evoked dopamine release from rat striatum.
Neuropharmacology 1996;35(11):1531-6.
1995: L Soliakov; T Gallagher; Susan Wonnacott
Anatoxin-a-evoked [3H]dopamine release from rat striatal synaptosomes.
Neuropharmacology 1995;34(11):1535-41.
1995: M Amar; P Thomas; Susan Wonnacott; George Lunt
A nicotinic acetylcholine receptor subunit from insect brain forms a non-desensitising homo-oligomeric nicotinic acetylcholine receptor when expressed in Xenopus oocytes.
Neuroscience letters 1995;199(2):107-10.
1995: Paul Whiteaker; H S Garcha; Susan Wonnacott; Ian P Stolerman
Locomotor activation and dopamine release produced by nicotine and isoarecolone in rats.
British journal of pharmacology 1995;116(3):2097-105.
1995: G E Barrantes; C T Murphy; John Westwick; Susan Wonnacott
Nicotine increases intracellular calcium in rat hippocampal neurons via voltage-gated calcium channels.
Neuroscience letters 1995;196(1-2):101-4.
1995: L Molloy; Susan Wonnacott; T Gallagher; P A Brough; Bruce G Livett
Anatoxin-a is a potent agonist of the nicotinic acetylcholine receptor of bovine adrenal chromaffin cells.
European journal of pharmacology 1995;289(3):447-53.
1995: D J Hardick; G Cooper; T Scott-Ward; Ian S Blagbrough; B V Potter; Susan Wonnacott
Conversion of the sodium channel activator aconitine into a potent alpha 7-selective nicotinic ligand.
FEBS letters 1995;365(1):79-82.
1995: G E Barrantes; A T Rogers; J Lindstrom; Susan Wonnacott
alpha-Bungarotoxin binding sites in rat hippocampal and cortical cultures: initial characterisation, colocalisation with alpha 7 subunits and up-regulation by chronic nicotine treatment.
Brain research 1995;672(1-2):228-36.
1995: A T Rogers; Susan Wonnacott
Nicotine-induced upregulation of alpha bungarotoxin (alpha Bgt) binding sites in cultured rat hippocampal neurons.
Biochemical Society transactions 1995;23(1):48S.
1994: A Aplin; Susan Wonnacott
Interaction of p-aminophenyldichloroarsine, an arsenical with specificity for vicinal cysteines, with [3H]cytisine binding sites in rat brain membranes.
Biochemical pharmacology 1994;48(3):473-7.
1994: G E Barrantes; John Westwick; Susan Wonnacott
Nicotinic acetylcholine receptors in primary cultures of hippocampal neurons: pharmacology and Ca++ permeability.
Biochemical Society transactions 1994;22(3):294S.
1993: M Amar; P Thomas; C Johnson; George Lunt; Susan Wonnacott
Agonist pharmacology of the neuronal alpha 7 nicotinic receptor expressed in Xenopus oocytes.
FEBS letters 1993;327(3):284-8.
1993: E M Sanderson; A L Drasdo; K McCrea; Susan Wonnacott
Upregulation of nicotinic receptors following continuous infusion of nicotine is brain-region-specific.
Brain research 1993;617(2):349-52.
1993: G I Wilkie; P H Hutson; M W Stephens; P Whiting; Susan Wonnacott
Hippocampal nicotinic autoreceptors modulate acetylcholine release.
Biochemical Society transactions 1993;21(2):429-31.
1993: H S Garcha; P Thomas; C E Spivak; Susan Wonnacott; Ian P Stolerman
Behavioural and ligand-binding studies in rats with 1-acetyl-4-methylpiperazine, a novel nicotinic agonist.
Psychopharmacology 1993;110(3):347-54.
1992: A Drasdo; M Caulfield; D Bertrand; S Bertrand; Susan Wonnacott
Methyl lycaconitine: A novel nicotinic antagonist.
Molecular and cellular neurosciences 1992;3(3):237-43.
1992: Manickavasagom Alkondon; Edna F R Pereira; Susan Wonnacott; Edson X Albuquerque
Blockade of nicotinic currents in hippocampal neurons defines methyllycaconitine as a potent and specific receptor antagonist.
Molecular pharmacology 1992;41(4):802-8.
1992: Susan Wonnacott; K L Swanson; Edson X Albuquerque; N J Huby; P Thompson; T Gallagher
Homoanatoxin: a potent analogue of anatoxin-A.
Biochemical pharmacology 1992;43(3):419-23.
1991: Susan Wonnacott; S Jackman; K L Swanson; H Rapoport; Edson X Albuquerque
Nicotinic pharmacology of anatoxin analogs. II. Side chain structure-activity relationships at neuronal nicotinic ligand binding sites.
The Journal of pharmacology and experimental therapeutics 1991;259(1):387-91.
1991: K L Swanson; R S Aronstam; Susan Wonnacott; H Rapoport; Edson X Albuquerque
Nicotinic pharmacology of anatoxin analogs. I. Side chain structure-activity relationships at peripheral agonist and noncompetitive antagonist sites.
The Journal of pharmacology and experimental therapeutics 1991;259(1):377-86.
1991: Susan Wonnacott
The relevance of receptor binding studies to tobacco research.
British journal of addiction 1991;86(5):537-41.
1991: Susan Wonnacott
Neuronal nicotinic receptors: functional correlates of ligand binding sites.
Biochemical Society transactions 1991;19(1):121-4.
1991: B Thorne; Susan Wonnacott; P R Dunkley
Isolation of hippocampal synaptosomes on Percoll gradients: cholinergic markers and ligand binding sites.
Journal of neurochemistry 1991;56(2):479-84.
1990: P P Rowell; Susan Wonnacott
Evidence for functional activity of up-regulated nicotine binding sites in rat striatal synaptosomes.
Journal of neurochemistry 1990;55(6):2105-10.
1990: Susan Wonnacott; B Thorne
Separation of pre- and post-synaptic receptors on Percoll gradients.
Biochemical Society transactions 1990;18(5):885-6.
1990: J M Ward; V B Cockcroft; George Lunt; F S Smillie; Susan Wonnacott
Methyllycaconitine: a selective probe for neuronal alpha-bungarotoxin binding sites.
FEBS letters 1990;270(1-2):45-8.
1990: A S Ramoa; Manickavasagom Alkondon; Yasco Aracava; J Irons; George Lunt; S S Deshpande; Susan Wonnacott; R S Aronstam; Edson X Albuquerque
The anticonvulsant MK-801 interacts with peripheral and central nicotinic acetylcholine receptor ion channels.
The Journal of pharmacology and experimental therapeutics 1990;254(1):71-82.
1990: C Rapier; George Lunt; Susan Wonnacott
Nicotinic modulation of [3H]dopamine release from striatal synaptosomes: pharmacological characterisation.
Journal of neurochemistry 1990;54(3):937-45.
1989: R Rozental; Yasco Aracava; G T Scoble; K L Swanson; Susan Wonnacott; Edson X Albuquerque
Agonist recognition site of the peripheral acetylcholine receptor ion channel complex differentiates the enantiomers of nicotine.
The Journal of pharmacology and experimental therapeutics 1989;251(2):395-404.
1989: Susan Wonnacott; J Irons; C Rapier; B Thorne; George Lunt
Presynaptic modulation of transmitter release by nicotinic receptors.
Progress in brain research 1989;79():157-63.
1988: Nigel J Cairns; Susan Wonnacott
[3H](-)nicotine binding sites in fetal human brain.
Brain research 1988;475(1):1-7.
1988: C Rapier; George Lunt; Susan Wonnacott
Stereoselective nicotine-induced release of dopamine from striatal synaptosomes: concentration dependence and repetitive stimulation.
Journal of neurochemistry 1988;50(4):1123-30.
1988: D R Macallan; George Lunt; Susan Wonnacott; K L Swanson; H Rapoport; Edson X Albuquerque
Methyllycaconitine and (+)-anatoxin-a differentiate between nicotinic receptors in vertebrate and invertebrate nervous systems.
FEBS letters 1988;226(2):357-63.
1987: Yasco Aracava; S S Deshpande; K L Swanson; H Rapoport; Susan Wonnacott; George Lunt; Edson X Albuquerque
Nicotinic acetylcholine receptors in cultured neurons from the hippocampus and brain stem of the rat characterized by single channel recording.
FEBS letters 1987;222(1):63-70.
1987: C Rapier; Susan Wonnacott; George Lunt; Edson X Albuquerque
The neurotoxin histrionicotoxin interacts with the putative ion channel of the nicotinic acetylcholine receptors in the central nervous system.
FEBS letters 1987;212(2):292-6.
1985: J Whyte; Roger Harrison; George Lunt; Susan Wonnacott
Properties of ?-bungarotoxin binding sites in foetal human brain.
Neurochemistry international 1985;7(3):515-23.
1985: C Rapier; Roger Harrison; George Lunt; Susan Wonnacott
Neosurugatoxin blocks nicotinic acetylcholine receptors in the brain.
Neurochemistry international 1985;7(2):389-96.
1984: A Mills; Susan Wonnacott
Antibodies to nicotinic acetylcholine receptors used to probe the structural and functional relationships between brain ?-bungarotoxin binding sites and nicotinic receptors.
Neurochemistry international 1984;6(2):249-57.
1982: Susan Wonnacott; R Harrison; G Lunt
Immunological cross-reactivity between the alpha-bungarotoxin-binding component from rat brain and nicotinic acetylcholine receptor.
Journal of neuroimmunology 1982;3(1):1-13.