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Alastair Wood

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
52
Stein, Michael
23
Xie, Hong-Guang
21
Kim, Richard
19
Wilkinson, Grant
19
Sofowora, Gbenga
14
He, Huai
14
Dishy, Victor
13
Zhou, Hong-Hao
11
Kurnik, Daniel
11
Lang, Chim
11
Muszkat, Mordechai
9
Caraco, Y
9
Wandel, Cristoph
8
Harris, Paul
8
Roden, Dan

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Publications

TOP 3
Parker Ruth M; Wolf Michael S; Jacobson Kara L; Wood Alastair J J
Risk of confusion in dosing Tamiflu oral suspension in children.
Friedman Eitan A; Harris Paul A; Wood Alastair J J; Stein C Michael; Kurnik Daniel
The alpha2C-adrenoceptor deletion322-325 variant and cold-induced vasoconstriction.
Wood Alastair J J
Progress and deficiencies in the registration of clinical trials.

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All Publications

2009: Parker Ruth M; Wolf Michael S; Jacobson Kara L; Wood Alastair J J
Risk of confusion in dosing Tamiflu oral suspension in children.
The New England journal of medicine 2009;361(19):1912-3.
2009: Friedman Eitan A; Harris Paul A; Wood Alastair J J; Stein C Michael; Kurnik Daniel
The alpha2C-adrenoceptor deletion322-325 variant and cold-induced vasoconstriction.
Clinical autonomic research : official journal of the Clinical Autonomic Research Society 2009;19(4):247-54.
2009: Wood Alastair J J
Progress and deficiencies in the registration of clinical trials.
The New England journal of medicine 2009;360(8):824-30.
2008: Kurnik Daniel; Sofowora Gbenga G; Donahue John P; Nair Usha B; Wilkinson Grant R; Wood Alastair J J; Muszkat Mordechai
Tariquidar, a selective P-glycoprotein inhibitor, does not potentiate loperamide's opioid brain effects in humans despite full inhibition of lymphocyte P-glycoprotein.
Anesthesiology 2008;109(6):1092-9.
2008: Kurnik Daniel; Li Chun; Sofowora Gbenga G; Friedman Eitan A; Muszkat Mordechai; Xie Hong-Guang; Harris Paul A; Williams Scott M; Nair Usha B; Wood Alastair J J; Stein C Michael
Beta-1-adrenoceptor genetic variants and ethnicity independently affect response to beta-blockade.
Pharmacogenetics and genomics 2008;18(10):895-902.
2008: Kurnik Daniel; Friedman Eitan A; Muszkat Mordechai; Sofowora Gbenga G; Xie Hong-Guang; Dupont William D; Wood Alastair J J; Stein C Michael
Genetic variants in the alpha2C-adrenoceptor and G-protein contribute to ethnic differences in cardiovascular stress responses.
Pharmacogenetics and genomics 2008;18(9):743-50.
2008: Wood Alastair J J
Playing "kick the FDA"--risk-free to players but hazardous to public health.
The New England journal of medicine 2008;358(17):1774-5.
2008: Kurnik Daniel; Muszkat Mordechai; Sofowora Gbenga G; Friedman Eitan A; Dupont William D; Scheinin Mika; Wood Alastair J J; Stein C Michael
Ethnic and genetic determinants of cardiovascular response to the selective alpha 2-adrenoceptor agonist dexmedetomidine.
Hypertension 2008;51(2):406-11.
2007: Kurnik Daniel; Muszkat Mordechai; Friedman Eitan A; Sofowora Gbenga G; Diedrich André; Xie Hong-Guang; Harris Paul A; Choi Leena; Wood Alastair J J; Stein C Michael
Effect of the alpha2C-adrenoreceptor deletion322-325 variant on sympathetic activity and cardiovascular measures in healthy subjects.
Journal of hypertension 2007;25(4):763-71.
2007: Friedman E A; Harris P A; Wood A J J; Stein C M; Kurnik D
The effects of tadalafil on cold-induced vasoconstriction in patients with Raynaud's phenomenon.
Clinical pharmacology and therapeutics 2007;81(4):503-9.
2006: Kurnik Daniel; Wood Alastair J J; Wilkinson Grant R
The erythromycin breath test reflects P-glycoprotein function independently of cytochrome P450 3A activity.
Clinical pharmacology and therapeutics 2006;80(3):228-34.
2006: Wood Alastair J J
A proposal for radical changes in the drug-approval process.
The New England journal of medicine 2006;355(6):618-23.
2006: Choo Edna F; Kurnik Daniel; Muszkat Mordechai; Ohkubo Tadashi; Shay Sheila D; Higginbotham James N; Glaeser Hartmut; Kim Richard B; Wood Alastair J J; Wilkinson Grant R
Differential in vivo sensitivity to inhibition of P-glycoprotein located in lymphocytes, testes, and the blood-brain barrier.
The Journal of pharmacology and experimental therapeutics 2006;317(3):1012-8.
2006: Wood Alastair J J; Darbyshire Janet
Injury to research volunteers--the clinical-research nightmare.
The New England journal of medicine 2006;354(18):1869-71.
2006: Kurnik Daniel; Muszkat Mordechai; Li Chun; Sofowora Gbenga G; Solus Joseph; Xie Hong-Guang; Harris Paul A; Jiang Lan; McMunn Chara; Ihrie Patrick; Dawson Elliott P; Williams Scott M; Wood Alastair J J; Stein C Michael
Variations in the alpha2A-adrenergic receptor gene and their functional effects.
Clinical pharmacology and therapeutics 2006;79(3):173-85.
2005: Drazen Jeffrey M; Wood Alastair J J
Trial registration report card.
The New England journal of medicine 2005;353(26):2809-11.
2005: Wood Alastair J J; Drazen Jeffrey M; Greene Michael F
A sad day for science at the FDA.
The New England journal of medicine 2005;353(12):1197-9.
2005: Sofowora Gbemiga G; Singh Iqbal; He Huai B; Wood Alastair J J; Stein C Michael
Effect of acute transdermal estrogen administration on basal, mental stress and cold pressor-induced sympathetic responses in postmenopausal women.
Clinical autonomic research : official journal of the Clinical Autonomic Research Society 2005;15(3):193-9.
2005: Muszkat Mordechai; Kurnik Daniel; Solus Joseph; Sofowora Gbenga G; Xie Hong-Guang; Jiang Lan; McMunn Chara; Ihrie Patrick; Harris James R; Dawson Elliott P; Williams Scott M; Wood Alastair J J; Stein C Michael
Variation in the alpha2B-adrenergic receptor gene (ADRA2B) and its relationship to vascular response in vivo.
Pharmacogenetics and genomics 2005;15(6):407-14.
2005: Muszkat Mordechai; Sofowora Gbenga G; Xie Hong-Guang; Wood Alastair J J; Stein C Michael
Alpha2B adrenergic receptor 301-303 deletion polymorphism and vascular alpha2 adrenergic receptor response.
Pharmacogenetics and genomics 2005;15(1):23-8.
2004: Dishy Victor; Landau Ruth; Sofowora Gbenga G; Xie Hong-Guang; Smiley Richard M; Kim Richard B; Byrne Daniel W; Wood Alastair J J; Stein C Michael
Beta2-adrenoceptor Thr164Ile polymorphism is associated with markedly decreased vasodilator and increased vasoconstrictor sensitivity in vivo.
Pharmacogenetics 2004;14(8):517-22.
2004: Sofowora Gbenga G; Dishy Victor; Landau Ruth; Xie Hong-Guang; Prasad Harish C; Byrne Daniel W; Smiley Richard M; Kim Richard B; Wood Alastair J J; Stein C Michael
Alpha 1A-adrenergic receptor polymorphism and vascular response.
Clinical pharmacology and therapeutics 2004;75(6):539-45.
2004: Landau Ruth; Xie Hong-Guang; Dishy Victor; Wood Alastair J J; Stein C Michael; Smiley Richard M
No association of the Asp298 variant of the endothelial nitric oxide synthase gene with preeclampsia.
American journal of hypertension 2004;17(5 Pt 1):391-4.
2004: Xie Hong-Guang; Wood Alastair J J; Kim Richard B; Stein C Michael; Wilkinson Grant R
Genetic variability in CYP3A5 and its possible consequences.
Pharmacogenomics 2004;5(3):243-72.
2004: Drazen Jeffrey M; Greene Michael F; Wood Alastair J J
The FDA, politics, and plan B.
The New England journal of medicine 2004;350(15):1561-2.
2004: Dishy Victor; Harris Paul A; Pierce Rosanna; Prasad Harish C; Sofowora Gbenga; Bonar Holly L; Wood Alastair J J; Stein C Michael
Sildenafil does not improve nitric oxide-mediated endothelium-dependent vascular responses in smokers.
British journal of clinical pharmacology 2004;57(2):209-12.
2004: Muszkat Mordechai; Sofowora Gbenga G; Wood Alastair J J; Stein C Michael
Alpha2-adrenergic receptor-induced vascular constriction in blacks and whites.
Hypertension 2004;43(1):31-5.
2003: Haas David W; Wilkinson Grant R; Kuritzkes Daniel R; Richman Douglas D; Nicotera Janet; Mahon Laura F; Sutcliffe Cara; Siminski Sue; Andersen Janet; Coughlin Kristine; Clayton Ellen W; Haines Jonathan; Marshak Ann; Saag Michael; Lawrence Jody; Gustavson Jeffrey; Anne Bennett Jo; Christensen Rolf; Matula Margaret A; Wood Alastair J J;
A multi-investigator/institutional DNA bank for AIDS-related human genetic studies: AACTG Protocol A5128.
HIV clinical trials 2003;4(5):287-300.
2003: Sofowora G G; Dishy V; Muszkat M; Xie H G; Kim R B; Harris P A; Prasad H C; Byrne D W; Nair U B; Wood A J J; Stein C M
A common beta1-adrenergic receptor polymorphism (Arg389Gly) affects blood pressure response to beta-blockade.
Clinical pharmacology and therapeutics 2003;73(4):366-71.
2003: Dishy Victor; Gupta Simi; Landau Ruth; Xie Hong-Guang; Kim Richard B; Smiley Richard M; Byrne Daniel W; Wood Alastair J J; Stein C Michael
G-protein beta(3) subunit 825 C/T polymorphism is associated with weight gain during pregnancy.
Pharmacogenetics 2003;13(4):241-2.
2003: Dishy Victor; Sofowora Gbenga G; Imamura Hitoshi; Nishimi Yukihide; Xie Hong-Guang; Wood Alastair J; Stein C Michael
Nitric oxide production decreases after salt loading but is not related to blood pressure changes or nitric oxide-mediated vascular responses.
Journal of hypertension 2003;21(1):153-7.
2002: Wood Alastair J j
Variability in beta-adrenergic receptor response in the vasculature: Role of receptor polymorphism.
The Journal of allergy and clinical immunology 2002;110(6 Suppl):S318-21.
2002: Landau Ruth; Xie Hong-Guang; Dishy Victor; Stein C Micheal; Wood Alastair J J; Emala Charles W; Smiley Richard M
beta2-Adrenergic receptor genotype and preterm delivery.
American journal of obstetrics and gynecology 2002;187(5):1294-8.
2002: Landau Ruth; Dishy Victor; Wood Alastair J J; Stein C Michael; Smiley Richard M
Disproportionate decrease in alpha- compared with beta-adrenergic sensitivity in the dorsal hand vein in pregnancy favors vasodilation.
Circulation 2002;106(9):1116-20.
2002: Wood Alastair J J
When increased therapeutic benefit comes at increased cost.
The New England journal of medicine 2002;346(23):1819-21.
2001: Sofowora G; Dishy V; Xie H G; Imamura H; Nishimi Y; Morales C R; Morrow J D; Kim R B; Stein C M; Wood A J
In-vivo effects of Glu298Asp endothelial nitric oxide synthase polymorphism.
Pharmacogenetics 2001;11(9):809-14.
2001: Dishy V; Sofowora G G; Xie H G; Kim R B; Byrne D W; Stein C M; Wood A J
The effect of common polymorphisms of the beta2-adrenergic receptor on agonist-mediated vascular desensitization.
The New England journal of medicine 2001;345(14):1030-5.
2001: Dishy V; Sofowora G; Harris P A; Kandcer M; Zhan F; Wood A J; Stein C M
The effect of sildenafil on nitric oxide-mediated vasodilation in healthy men.
Clinical pharmacology and therapeutics 2001;70(3):270-9.
2001: Stein C M; Sadeque A J; Murray J J; Wandel C; Kim R B; Wood A J
Cyclosporine pharmacokinetics and pharmacodynamics in African American and white subjects.
Clinical pharmacology and therapeutics 2001;69(5):317-23.
2001: Xie H G; Dishy V; Sofowora G; Kim R B; Landau R; Smiley R M; Zhou H H; Wood A J; Harris P; Stein C M
Arg389Gly beta 1-adrenoceptor polymorphism varies in frequency among different ethnic groups but does not alter response in vivo.
Pharmacogenetics 2001;11(3):191-7.
2001: Stein C M; Lang C C; Xie H G; Wood A J
Hypertension in black people: study of specific genotypes and phenotypes will provide a greater understanding of interindividual and interethnic variability in blood pressure regulation than studies based on race.
Pharmacogenetics 2001;11(2):95-110.
2000: Stein C M; Lang C C; Singh I; He H B; Wood A J
Increased vascular adrenergic vasoconstriction and decreased vasodilation in blacks. Additive mechanisms leading to enhanced vascular reactivity.
Hypertension 2000;36(6):945-51.
2000: Sadeque A J; Wandel C; He H; Shah S; Wood A J
Increased drug delivery to the brain by P-glycoprotein inhibition.
Clinical pharmacology and therapeutics 2000;68(3):231-7.
2000: Wandel C; Kim R B; Guengerich F P; Wood A J
Mibefradil is a P-glycoprotein substrate and a potent inhibitor of both P-glycoprotein and CYP3A in vitro.
Drug metabolism and disposition: the biological fate of chemicals 2000;28(8):895-8.
2000: He H; Sadeque A; Erve J C; Wood A J; Hachey D L
Quantitation of loperamide and N-demethyl-loperamide in human plasma using electrospray ionization with selected reaction ion monitoring liquid chromatography-mass spectrometry.
Journal of chromatography. B, Biomedical sciences and applications 2000;744(2):323-31.
2000: Wandel C; Witte J S; Hall J M; Stein C M; Wood A J; Wilkinson G R
CYP3A activity in African American and European American men: population differences and functional effect of the CYP3A4*1B5'-promoter region polymorphism.
Clinical pharmacology and therapeutics 2000;68(1):82-91.
2000: Xie H G; Stein C M; Kim R B; Gainer J V; Sofowora G; Dishy V; Brown N J; Goree R E; Haines J L; Wood A J
Human beta2-adrenergic receptor polymorphisms: no association with essential hypertension in black or white Americans.
Clinical pharmacology and therapeutics 2000;67(6):670-5.
2000: Choo E F; Leake B; Wandel C; Imamura H; Wood A J; Wilkinson G R; Kim R B
Pharmacological inhibition of P-glycoprotein transport enhances the distribution of HIV-1 protease inhibitors into brain and testes.
Drug metabolism and disposition: the biological fate of chemicals 2000;28(6):655-60.
1999: Xie H G; Kim R B; Stein C M; Gainer J V; Brown N J; Wood A J
Alpha1A-adrenergic receptor polymorphism: association with ethnicity but not essential hypertension.
Pharmacogenetics 1999;9(5):651-6.
1999: Xie H G; Stein C M; Kim R B; Wilkinson G R; Flockhart D A; Wood A J
Allelic, genotypic and phenotypic distributions of S-mephenytoin 4'-hydroxylase (CYP2C19) in healthy Caucasian populations of European descent throughout the world.
Pharmacogenetics 1999;9(5):539-49.
1999: Kinirons M T; O'Shea D; Kim R B; Groopman J D; Thummel K E; Wood A J; Wilkinson G R
Failure of erythromycin breath test to correlate with midazolam clearance as a probe of cytochrome P4503A.
Clinical pharmacology and therapeutics 1999;66(3):224-31.
1999: Xie H G; Kim R B; Stein C M; Wilkinson G R; Wood A J
Genetic polymorphism of (S)-mephenytoin 4'-hydroxylation in populations of African descent.
British journal of clinical pharmacology 1999;48(3):402-8.
1999: Xie H G; Stein C M; Kim R B; Xiao Z S; He N; Zhou H H; Gainer J V; Brown N J; Haines J L; Wood A J
Frequency of functionally important beta-2 adrenoceptor polymorphisms varies markedly among African-American, Caucasian and Chinese individuals.
Pharmacogenetics 1999;9(4):511-6.
1999: Wandel C; Kim R B; Kajiji S; Guengerich P; Wilkinson G R; Wood A J
P-glycoprotein and cytochrome P-450 3A inhibition: dissociation of inhibitory potencies.
Cancer research 1999;59(16):3944-8.
1999: Caraco Y; Sheller J; Wood A J
Impact of ethnic origin and quinidine coadministration on codeine's disposition and pharmacodynamic effects.
The Journal of pharmacology and experimental therapeutics 1999;290(1):413-22.
1999: Kim R B; Wandel C; Leake B; Cvetkovic M; Fromm M F; Dempsey P J; Roden M M; Belas F; Chaudhary A K; Roden D M; Wood A J; Wilkinson G R
Interrelationship between substrates and inhibitors of human CYP3A and P-glycoprotein.
Pharmaceutical research 1999;16(3):408-14.
1998: Stein C M; He H B; Wood A J
Basal and stimulated sympathetic responses after epinephrine: no evidence of augmented responses.
Hypertension 1998;32(6):1016-21.
1998: Wood A J; Stein C M; Woosley R
Making medicines safer--the need for an independent drug safety board.
The New England journal of medicine 1998;339(25):1851-4.
1998: Wood A J
Ethnic differences in drug disposition and response.
Therapeutic drug monitoring 1998;20(5):525-6.
1998: Robbins I M; Cuiper L L; Stein C M; Wood A J; He H B; Parker R; Christman B W
Angiotensin II mediates systemic rebound hypertension after cessation of prostacyclin infusion in sheep.
Journal of applied physiology (Bethesda, Md. : 1985) 1998;85(2):731-7.
1998: Stein C M; Brown N; Vaughan D E; Lang C C; Wood A J
Regulation of local tissue-type plasminogen activator release by endothelium-dependent and endothelium-independent agonists in human vasculature.
Journal of the American College of Cardiology 1998;32(1):117-22.
1998: Wandel C; Lang C C; Cowart D C; Girard A F; Bramer S; Flockhart D A; Wood A J
Effect of CYP3A inhibition on vesnarinone metabolism in humans.
Clinical pharmacology and therapeutics 1998;63(5):506-11.
1998: He H; Shay S D; Caraco Y; Wood M; Wood A J
Simultaneous determination of codeine and its seven metabolites in plasma and urine by high-performance liquid chromatography with ultraviolet and electrochemical detection.
Journal of chromatography. B, Biomedical sciences and applications 1998;708(1-2):185-93.
1998: Kim R B; Fromm M F; Wandel C; Leake B; Wood A J; Roden D M; Wilkinson G R
The drug transporter P-glycoprotein limits oral absorption and brain entry of HIV-1 protease inhibitors.
The Journal of clinical investigation 1998;101(2):289-94.
1997: He H; Stein C M; Christman B; Wood A J
Determination of catecholamines in sheep plasma by high-performance liquid chromatography with electrochemical detection: comparison of deoxyepinephrine and 3,4-dihydroxybenzylamine as internal standard.
Journal of chromatography. B, Biomedical sciences and applications 1997;701(1):115-9.
1997: Stein C M; Nelson R; He H B; Wood M; Wood A J
Norepinephrine release in the human forearm: effects of epinephrine.
Hypertension 1997;30(5):1078-84.
1997: Stein C M; Lang C C; Nelson R; Brown M; Wood A J
Vasodilation in black Americans: attenuated nitric oxide-mediated responses.
Clinical pharmacology and therapeutics 1997;62(4):436-43.
1997: Lang C C; Stein C M; Nelson R A; He H B; Belas F J; Blair I A; Wood M; Wood A J
Sympathoinhibitory response to clonidine is blunted in patients with heart failure.
Hypertension 1997;30(3 Pt 1):392-7.
1997: Lang C C; Stein C M; He H B; Belas F J; Blair I A; Wood M; Wood A J
Blunted blood pressure response to central sympathoinhibition in normotensive blacks: increased importance of nonsympathetic factors in blood pressure maintenance in blacks.
Hypertension 1997;30(2 Pt 1):157-62.
1997: Lang C C; Rayos G H; Chomsky D B; Wood A J; Wilson J R
Effect of sympathoinhibition on exercise performance in patients with heart failure.
Circulation 1997;96(1):238-45.
1997: Stein C M; Brown N; Carlson M G; Campbell P; Wood A J
Coadministration of glyburide and minoxidil, drugs with opposing effects on potassium channels.
Clinical pharmacology and therapeutics 1997;61(6):662-8.
1997: Stein C M; Deegan R; Wood A J
Lack of correlation between arterial and venous beta-adrenergic receptor sensitivity.
Hypertension 1997;29(6):1273-7.
1997: Caraco Y; Sheller J; Wood A J
Pharmacogenetic determinants of codeine induction by rifampin: the impact on codeine's respiratory, psychomotor and miotic effects.
The Journal of pharmacology and experimental therapeutics 1997;281(1):330-6.
1997: Stein C M; Wood A J; Pincus T
Implementation of multiple outpatient formularies: undesirable effects.
Clinical pharmacology and therapeutics 1997;61(1):1-7.
1997: Tateishi T; Soucek P; Caraco Y; Guengerich F P; Wood A J
Colchicine biotransformation by human liver microsomes. Identification of CYP3A4 as the major isoform responsible for colchicine demethylation.
Biochemical pharmacology 1997;53(1):111-6.
1996: Caraco Y; Wilkinson G R; Wood A J
Differences between white subjects and Chinese subjects in the in vivo inhibition of cytochrome P450s 2C19, 2D6, and 3A by omeprazole.
Clinical pharmacology and therapeutics 1996;60(4):396-404.
1996: Caraco Y; Sheller J; Wood A J
Pharmacogenetic determination of the effects of codeine and prediction of drug interactions.
The Journal of pharmacology and experimental therapeutics 1996;278(3):1165-74.
1996: Caraco Y; Lagerstrom P O; Wood A J
Ethnic and genetic determinants of omeprazole disposition and effect.
Clinical pharmacology and therapeutics 1996;60(2):157-67.
1996: Caraco Y; Tateishi T; Guengerich F P; Wood A J
Microsomal codeine N-demethylation: cosegregation with cytochrome P4503A4 activity.
Drug metabolism and disposition: the biological fate of chemicals 1996;24(7):761-4.
1996: Lang C C; Stein C M; He H B; Wood A J
Angiotensin converting enzyme inhibition and sympathetic activity in healthy subjects.
Clinical pharmacology and therapeutics 1996;59(6):668-74.
1996: Robin D W; Hasan S S; Edeki T; Lichtenstein M J; Shiavi R G; Wood A J
Increased baseline sway contributes to increased losses of balance in older people following triazolam.
Journal of the American Geriatrics Society 1996;44(3):300-4.
1996: Kinirons M T; Lang C C; He H B; Ghebreselasie K; Shay S; Robin D W; Wood A J
Triazolam pharmacokinetics and pharmacodynamics in Caucasians and Southern Asians: ethnicity and CYP3A activity.
British journal of clinical pharmacology 1996;41(1):69-72.
1996: Tateishi T; Krivoruk Y; Ueng Y F; Wood A J; Guengerich F P; Wood M
Identification of human liver cytochrome P-450 3A4 as the enzyme responsible for fentanyl and sufentanil N-dealkylation.
Anesthesia and analgesia 1996;82(1):167-72.
1996: Stein C M; Kinirons M T; Pincus T; Wilkinson G R; Wood A J
Comparison of the dapsone recovery ratio and the erythromycin breath test as in vivo probes of CYP3A activity in patients with rheumatoid arthritis receiving cyclosporine.
Clinical pharmacology and therapeutics 1996;59(1):47-51.
1996: Lang C C; Brown R M; Kinirons M T; Deathridge M A; Guengerich F P; Kelleher D; O'Briain D S; Ghishan F K; Wood A J
Decreased intestinal CYP3A in celiac disease: reversal after successful gluten-free diet: a potential source of interindividual variability in first-pass drug metabolism.
Clinical pharmacology and therapeutics 1996;59(1):41-6.
1995: Tateishi T; Wood A J; Guengerich F P; Wood M
Biotransformation of tritiated fentanyl in human liver microsomes. Monitoring metabolism using phenylacetic acid and 2-phenylethanol.
Biochemical pharmacology 1995;50(11):1921-4.
1995: Stein C M; Nelson R; Brown M; He H; Wood M; Wood A J
Dietary sodium intake modulates systemic but not forearm norepinephrine release.
Clinical pharmacology and therapeutics 1995;58(4):425-33.
1995: Stein C M; He H; Pincus T; Wood A J
Cyclosporine impairs vasodilation without increased sympathetic activity in humans.
Hypertension 1995;26(4):705-10.
1995: Lang C C; Stein C M; Brown R M; Deegan R; Nelson R; He H B; Wood M; Wood A J
Attenuation of isoproterenol-mediated vasodilatation in blacks.
The New England journal of medicine 1995;333(3):155-60.
1995: Caraco Y; Tateishi T; Wood A J
Interethnic difference in omeprazole's inhibition of diazepam metabolism.
Clinical pharmacology and therapeutics 1995;58(1):62-72.
1995: Stein C M; Nelson R; Deegan R; He H; Wood M; Wood A J
Forearm beta adrenergic receptor-mediated vasodilation is impaired, without alteration of forearm norepinephrine spillover, in borderline hypertension.
The Journal of clinical investigation 1995;96(1):579-85.
1995: Deegan R; He H B; Krivoruk Y; Wood A J; Wood M
Regulation of norepinephrine release by beta 2-adrenergic receptors during halothane anesthesia.
Anesthesiology 1995;82(6):1417-25.
1995: Stein C M; Nelson R; Deegan R; He H; Inagami T; Frazer M; Badr K F; Wood M; Wood A J
Tachyphylaxis of human forearm vascular responses does not occur rapidly after exposure to isoproterenol.
Hypertension 1995;25(6):1294-300.
1995: Stein C M; Nelson R; Brown M; Wood M; Wood A J
Dietary sodium intake modulates vasodilation mediated by nitroprusside but not by methacholine in the human forearm.
Hypertension 1995;25(6):1220-3.
1995: Zhou H H; Wood A J
Stereoselective disposition of carvedilol is determined by CYP2D6.
Clinical pharmacology and therapeutics 1995;57(5):518-24.
1994: Krivoruk Y; Kinirons M T; Wood A J; Wood M
Metabolism of cytochrome P4503A substrates in vivo administered by the same route: lack of correlation between alfentanil clearance and erythromycin breath test.
Clinical pharmacology and therapeutics 1994;56(6 Pt 1):608-14.
1994: He H; Edeki T I; Wood A J
Determination of low plasma timolol concentrations following topical application of timolol eye drops in humans by high-performance liquid chromatography with electrochemical detection.
Journal of chromatography. B, Biomedical applications 1994;661(2):351-6.
1994: Deegan R; Wood A J
Beta-receptor antagonism does not fully explain esmolol-induced hypotension.
Clinical pharmacology and therapeutics 1994;56(2):223-8.
1993: Robin D W; Lee M; Hasan S S; Wood A J
Triazolam in cirrhosis: pharmacokinetics and pharmacodynamics.
Clinical pharmacology and therapeutics 1993;54(6):630-7.
1993: Kinirons M T; O'Shea D; Downing T E; Fitzwilliam A T; Joellenbeck L; Groopman J D; Wilkinson G R; Wood A J
Absence of correlations among three putative in vivo probes of human cytochrome P4503A activity in young healthy men.
Clinical pharmacology and therapeutics 1993;54(6):621-9.
1993: Zhou H H; Sheller J R; Nu H; Wood M; Wood A J
Ethnic differences in response to morphine.
Clinical pharmacology and therapeutics 1993;54(5):507-13.
1993: Stein M; Deegan R; Wood A J
Long-term exposure to beta 2-receptor agonist specifically desensitizes beta-receptor-mediated venodilation.
Clinical pharmacology and therapeutics 1993;54(2):187-93.
1993: Stein M; Deegan R; He H; Wood A J
Beta-adrenergic receptor-mediated release of norepinephrine in the human forearm.
Clinical pharmacology and therapeutics 1993;54(1):58-64.
1993: Deegan R; He H B; Wood A J; Wood M
Effect of enflurane and isoflurane on norepinephrine kinetics: a new approach to assessment of sympathetic function during anesthesia.
Anesthesia and analgesia 1993;77(1):49-54.
1992: Yun C H; Wood M; Wood A J; Guengerich F P
Identification of the pharmacogenetic determinants of alfentanil metabolism: cytochrome P-450 3A4. An explanation of the variable elimination clearance.
Anesthesiology 1992;77(3):467-74.
1992: Zhou H H; Adedoyin A; Wood A J
Differing effect of atropine on heart rate in Chinese and white subjects.
Clinical pharmacology and therapeutics 1992;52(2):120-4.
1992: Edeki T; Robin D W; Prakash C; Blair I A; Wood A J
Sensitive assay for triazolam in plasma following low oral doses.
Journal of chromatography 1992;577(1):190-4.
1992: He H B; Deegan R J; Wood M; Wood A J
Optimization of high-performance liquid chromatographic assay for catecholamines. Determination of optimal mobile phase composition and elimination of species-dependent differences in extraction recovery of 3,4-dihydroxybenzylamine.
Journal of chromatography 1992;574(2):213-8.
1992: Zhou H H; Whelan E; Wood A J
Lack of effect of ageing on the stereochemical disposition of propranolol.
British journal of clinical pharmacology 1992;33(1):121-3.
1991: Deegan R; He H B; Wood A J; Wood M
Effects of anesthesia on norepinephrine kinetics. Comparison of propofol and halothane anesthesia in dogs.
Anesthesiology 1991;75(3):481-8.
1991: Zhou H H; Wood A J
Increased suppression of exercise-induced increase in renin by propranolol in Chinese subjects.
Clinical pharmacology and therapeutics 1991;50(2):150-6.
1991: Robin D W; Hasan S S; Lichtenstein M J; Shiavi R G; Wood A J
Dose-related effect of triazolam on postural sway.
Clinical pharmacology and therapeutics 1991;49(5):581-8.
1991: Wood A J; Zhou H H
Ethnic differences in drug disposition and responsiveness.
Clinical pharmacokinetics 1991;20(5):350-73.
1991: Perry S M; Whelan E; Shay S; Wood A J; Wood M
Effect of i.v. anaesthesia with propofol on drug distribution and metabolism in the dog.
British journal of anaesthesia 1991;66(1):66-72.
1990: Zhou H H; Anthony L B; Wood A J; Wilkinson G R
Induction of polymorphic 4'-hydroxylation of S-mephenytoin by rifampicin.
British journal of clinical pharmacology 1990;30(3):471-5.
1990: Funck-Brentano C; Silberstein D J; Roden D M; Wood A J; Woosley R L
A mechanism of D-(+)-sotalol effects on heart rate not related to beta-adrenoceptor antagonism.
British journal of clinical pharmacology 1990;30(2):195-202.
1990: Naslund T; Silberstein D J; Merrell W J; Nadeau J H; Wood A J
Low sodium intake corrects abnormality in beta-receptor-mediated arterial vasodilation in patients with hypertension: correlation with beta-receptor function in vitro.
Clinical pharmacology and therapeutics 1990;48(1):87-95.
1990: Zhou H H; Wood A J
Differences in stereoselective disposition of propranolol do not explain sensitivity differences between white and Chinese subjects: correlation between the clearance of (-)- and (+)-propranolol.
Clinical pharmacology and therapeutics 1990;47(6):719-23.
1990: Zhou H H; Anthony L B; Roden D M; Wood A J
Quinidine reduces clearance of (+)-propranolol more than (-)-propranolol through marked reduction in 4-hydroxylation.
Clinical pharmacology and therapeutics 1990;47(6):686-93.
1990: Lee J T; Kroemer H K; Silberstein D J; Funck-Brentano C; Lineberry M D; Wood A J; Roden D M; Woosley R L
The role of genetically determined polymorphic drug metabolism in the beta-blockade produced by propafenone.
The New England journal of medicine 1990;322(25):1764-8.
1990: Murray K T; Reilly C; Koshakji R P; Roden D M; Lineberry M D; Wood A J; Siddoway L A; Barbey J T; Woosley R L
Suppression of ventricular arrhythmias in man by d-propranolol independent of beta-adrenergic receptor blockade.
The Journal of clinical investigation 1990;85(3):836-42.
1990: Merrell W J; Gordon L; Wood A J; Shay S; Jackson E K; Wood M
The effect of halothane on morphine disposition: relative contributions of the liver and kidney to morphine glucuronidation in the dog.
Anesthesiology 1990;72(2):308-14.
1989: Wood A J
Calcium antagonists. Pharmacologic differences and similarities.
Circulation 1989;80(6 Suppl):IV184-8.
1989: Whelan E; Wood A J; Koshakji R; Shay S; Wood M
Halothane inhibition of propranolol metabolism is stereoselective.
Anesthesiology 1989;71(4):561-4.
1989: Anthony L; Koshakji R; Wood A J
Multiple pathways of propranolol's metabolism are inhibited by debrisoquin.
Clinical pharmacology and therapeutics 1989;46(3):297-300.
1989: Whelan E; Wood A J; Shay S; Wood M
Lack of effect of spinal anesthesia on drug metabolism.
Anesthesia and analgesia 1989;69(3):307-12.
1989: Prakash C; Koshakji R P; Wood A J; Blair I A
Simultaneous determination of propranolol enantiomers in plasma by high-performance liquid chromatography with fluorescence detection.
Journal of pharmaceutical sciences 1989;78(9):771-5.
1989: Rigby J W; Wood A J
Use of N-ethylmaleimide to directly determine the proportion of beta-adrenergic receptors exhibiting high affinity for agonists on human mononuclear leukocyte membranes.
Biochemical pharmacology 1989;38(17):2755-61.
1989: Zhou H H; Silberstein D J; Koshakji R P; Wood A J
Interindividual differences in beta-receptor density contribute to variability in response to beta-adrenoceptor antagonists.
Clinical pharmacology and therapeutics 1989;45(6):587-92.
1989: Kroemer H K; Funck-Brentano C; Silberstein D J; Wood A J; Eichelbaum M; Woosley R L; Roden D M
Stereoselective disposition and pharmacologic activity of propafenone enantiomers.
Circulation 1989;79(5):1068-76.
1989: Bullington J; Mouton Perry S M; Rigby J; Pinkerton M; Rogers D; Lewis T C; Preganz P; Wood A J; Wood M
The effect of advancing age on the sympathetic response to laryngoscopy and tracheal intubation.
Anesthesia and analgesia 1989;68(5):603-8.
1989: Shaheen O; Biollaz J; Koshakji R P; Wilkinson G R; Wood A J
Influence of debrisoquin phenotype on the inducibility of propranolol metabolism.
Clinical pharmacology and therapeutics 1989;45(4):439-43.
1989: Zhou H H; Koshakji R P; Silberstein D J; Wilkinson G R; Wood A J
Altered sensitivity to and clearance of propranolol in men of Chinese descent as compared with American whites.
The New England journal of medicine 1989;320(9):565-70.
1989: Silberstein D J; Rigby J; Merrell J; Naslund T; Wood A J
Altered beta-adrenoceptor internalization does not explain reduced beta-adrenergic responsiveness in the elderly.
The Journal of clinical endocrinology and metabolism 1989;68(1):131-4.
1988: Naslund T C; Merrell W J; Nadeau J H; Wood A J
Alpha-adrenergic blockade makes minimal contribution to ketanserin's hypotensive effect.
Clinical pharmacology and therapeutics 1988;44(6):699-703.
1988: Reilly C S; Merrell J; Wood A J; Koshakji R P; Wood M
Comparison of the effects of isoflurane or fentanyl-nitrous oxide anaesthesia on propranolol disposition in dogs.
British journal of anaesthesia 1988;60(7):791-6.
1988: Wood A J
Drug interactions in hypertension.
Hypertension 1988;11(3 Pt 2):II1-3.
1987: Koshakji R P; Wood A J
Improved high-performance liquid chromatographic method for the simultaneous determination of propranolol and 4-hydroxypropranolol in plasma with fluorescence detection.
Journal of chromatography 1987;422():294-300.
1986: Bergstrand R H; Wang T; Roden D M; Avant G R; Sutton W W; Siddoway L A; Wolfenden H; Woosley R L; Wilkinson G R; Wood A J
Encainide disposition in patients with chronic cirrhosis.
Clinical pharmacology and therapeutics 1986;40(2):148-54.
1986: Reilly C S; Biollaz J; Koshakji R P; Wood A J
Enprostil, in contrast to cimetidine, does not inhibit propranolol metabolism.
Clinical pharmacology and therapeutics 1986;40(1):37-41.
1985: Reilly C S; Wood M; Koshakji R P; Wood A J
Ultra-short-acting beta-blockade: a comparison with conventional beta-blockade.
Clinical pharmacology and therapeutics 1985;38(5):579-85.
1985: Reilly C S; Wood A J; Koshakji R P; Wood M
The effect of halothane on drug disposition: contribution of changes in intrinsic drug metabolizing capacity and hepatic blood flow.
Anesthesiology 1985;63(1):70-6.

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