FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

William Wood

Research Profile

Chemicals & Drugs

Living Beings

Genes & Molecular Sequences

Multigene Family

Disorders

Anatomy

Physiology

Concepts & Ideas

Molecular Sequence Data

Co-author Network

Publications

TOP 3
Monika S Kowalczyk; Gillian M Morriss-Kay; Chris P Ponting; Amy E Roberts; Luis Sanchez-Pulido; Jacqueline A Sharpe; Jacqueline A Sloane-Stanley; Leslie B Smoot; Dorota Szumska; Hugh Watkins; William G Wood; Christian Babbs; Shoumo Bhattacharya; Richard J Gibbons; Jim R Hughes; Douglas R Higgs
Nprl3 is required for normal development of the cardiovascular system.
Monika S Kowalczyk; Magnus D Lynch; Simon J McGowan; Thomas A Milne; Jacqueline A Sharpe; Jacqueline A Sloane-Stanley; Stephen Taylor; Douglas Vernimmen; William G Wood; Jill M Brown; Veronica Buckle; Licio Collavin; Marco De Gobbi; Jonathan Flint; David Garrick; Richard J Gibbons; Nicola E Gray; Mona Hosseini; Jim R Hughes; Douglas R Higgs
Intragenic enhancers act as alternative promoters.
Raffaele Renella; Nigel A Roberts; Jacqueline A Sharpe; Jacqueline A Sloane-Stanley; Louise Bird; Jill M Brown; Veronica Buckle; Jacqueline Cordell; Marco De Gobbi; David J P Ferguson; Tasneem Hassanali; Douglas R Higgs; William G Wood
Codanin-1 mutations in congenital dyserythropoietic anemia type 1 affect HP1{alpha} localization in erythroblasts.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of William Wood (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2012: Monika S Kowalczyk; Gillian M Morriss-Kay; Chris P Ponting; Amy E Roberts; Luis Sanchez-Pulido; Jacqueline A Sharpe; Jacqueline A Sloane-Stanley; Leslie B Smoot; Dorota Szumska; Hugh Watkins; William G Wood; Christian Babbs; Shoumo Bhattacharya; Richard J Gibbons; Jim R Hughes; Douglas R Higgs
Nprl3 is required for normal development of the cardiovascular system.
Mammalian genome : official journal of the International Mammalian Genome Society 2012;23(7-8):404-15.
2012: Monika S Kowalczyk; Magnus D Lynch; Simon J McGowan; Thomas A Milne; Jacqueline A Sharpe; Jacqueline A Sloane-Stanley; Stephen Taylor; Douglas Vernimmen; William G Wood; Jill M Brown; Veronica Buckle; Licio Collavin; Marco De Gobbi; Jonathan Flint; David Garrick; Richard J Gibbons; Nicola E Gray; Mona Hosseini; Jim R Hughes; Douglas R Higgs
Intragenic enhancers act as alternative promoters.
Molecular cell 2012;45(4):447-58.
2011: Raffaele Renella; Nigel A Roberts; Jacqueline A Sharpe; Jacqueline A Sloane-Stanley; Louise Bird; Jill M Brown; Veronica Buckle; Jacqueline Cordell; Marco De Gobbi; David J P Ferguson; Tasneem Hassanali; Douglas R Higgs; William G Wood
Codanin-1 mutations in congenital dyserythropoietic anemia type 1 affect HP1{alpha} localization in erythroblasts.
Blood 2011;117(25):6928-38.
2011: Alison T Merryweather-Clarke; Ann Atzberger; Shamit Soneji; Nicki Gray; Kevin Clark; Craig Waugh; Simon J McGowan; Stephen Taylor; Asoke K Nandi; William G Wood; David J Roberts; Douglas R Higgs; Veronica Buckle; Kathryn J H Robson
Global gene expression analysis of human erythroid progenitors.
Blood 2011;117(13):e96-108.
2009: Douglas Vernimmen; Fatima Marques-Kranc; Jacqueline A Sharpe; Jacqueline A Sloane-Stanley; William G Wood; Helen A C Wallace; Andrew J H Smith; Douglas R Higgs
Chromosome looping at the human alpha-globin locus is mediated via the major upstream regulatory element (HS -40).
Blood 2009;114(19):4253-60.
2009: Raffaele Renella; William G Wood
The congenital dyserythropoietic anemias.
Hematology/oncology clinics of North America 2009;23(2):283-306.
2009: Stephen R F Twigg; Christopher Healy; Christian Babbs; Jacqueline A Sharpe; William G Wood; Paul T Sharpe; Gillian M Morriss-Kay; Andrew O M Wilkie
Skeletal analysis of the Fgfr3(P244R) mouse, a genetic model for the Muenke craniosynostosis syndrome.
Developmental dynamics : an official publication of the American Association of Anatomists 2009;238(2):331-42.
2008: Jill M Brown; Joanne Green; Ricardo Neves; Helen A C Wallace; Andrew J H Smith; Jim Hughes; Nicki Gray; Steve Taylor; William G Wood; Douglas R Higgs; Francisco J Iborra; Veronica Buckle
Association between active genes occurs at nuclear speckles and is modulated by chromatin environment.
The Journal of cell biology 2008;182(6):1083-97.
2008: Douglas R Higgs; William G Wood
Genetic complexity in sickle cell disease.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(33):11595-6.
2008: Douglas R Higgs; William G Wood
Long-range regulation of alpha globin gene expression during erythropoiesis.
Current opinion in hematology 2008;15(3):176-83.
2007: Marco De Gobbi; Eduardo Anguita; Jim Hughes; Jacqueline A Sloane-Stanley; Jacqueline A Sharpe; Christoph M Koch; Carl Bruder; Richard J Gibbons; William G Wood; Douglas R Higgs
Tissue-specific histone modification and transcription factor binding in alpha globin gene expression.
Blood 2007;110(13):4503-10.
2007: Mary R Muers; Jacqueline A Sharpe; David Garrick; Jacqueline A Sloane-Stanley; Patrick M Nolan; Terry Hacker; William G Wood; Douglas R Higgs; Richard J Gibbons
Defining the cause of skewed X-chromosome inactivation in X-linked mental retardation by use of a mouse model.
American journal of human genetics 2007;80(6):1138-49.
2007: Douglas Vernimmen; Marco De Gobbi; Jacqueline A Sloane-Stanley; William G Wood; Douglas R Higgs
Long-range chromosomal interactions regulate the timing of the transition between poised and active gene expression.
The EMBO journal 2007;26(8):2041-51.
2007: Helen A C Wallace; Fatima Marques-Kranc; Melville Richardson; Francisco Luna-Crespo; Jacqueline A Sharpe; Jim Hughes; William G Wood; Douglas R Higgs; Andrew J H Smith
Manipulating the mouse genome to engineer precise functional syntenic replacements with human sequence.
Cell 2007;128(1):197-209.
2006: Jacqueline A Sloane-Stanley; Nigel A Roberts; Nancy F Olivieri; David J Weatherall; William G Wood
Globin gene expression in Hb Lepore-BAC transgenic mice.
British journal of haematology 2006;135(5):735-7.
2006: Momin R Ahmed; Aref Chehal; Laila Zahed; Ali Taher; Joud H Haidar; Ali Shamseddine; Anne-Marie O'Hea; Nicola Bienz; Orly Dgany; Nili Avidan; Jacques Beckmann; Hannah Tamary; Douglas Higgs; Paresh Vyas; William G Wood; Sunitha N Wickramasinghe
Linkage and mutational analysis of the CDAN1 gene reveals genetic heterogeneity in congenital dyserythropoietic anemia type I.
Blood 2006;107(12):4968-9.
2006: Marco De Gobbi; Vip Viprakasit; Jim R Hughes; Chris Fisher; Veronica Buckle; Helena Ayyub; Richard J Gibbons; Douglas Vernimmen; Yuko Yoshinaga; Pieter de Jong; Jan-Fang Cheng; Edward M Rubin; William G Wood; Don Bowden; Douglas R Higgs
A regulatory SNP causes a human genetic disease by creating a new transcriptional promoter.
Science (New York, N.Y.) 2006;312(5777):1215-7.
2006: Vip Viprakasit; Cornelis L Harteveld; Helena Ayyub; Jackie S Stanley; Piero C Giordano; William G Wood; Douglas R Higgs
A novel deletion causing alpha thalassemia clarifies the importance of the major human alpha globin regulatory element.
Blood 2006;107(9):3811-2.
2006: David Garrick; Jacqueline A Sharpe; Ruth Arkell; Lorraine Dobbie; Andrew J H Smith; William G Wood; Douglas R Higgs; Richard J Gibbons
Loss of Atrx affects trophoblast development and the pattern of X-inactivation in extraembryonic tissues.
PLoS genetics 2006;2(4):e58.
2006: Jill M Brown; Joanne Leach; Joyce E Reittie; Ann Atzberger; Jane Lee-Prudhoe; William G Wood; Douglas R Higgs; Francisco J Iborra; Veronica Buckle
Coregulated human globin genes are frequently in spatial proximity when active.
The Journal of cell biology 2006;172(2):177-87.
2006: Douglas R Higgs; Douglas Vernimmen; Marco De Gobbi; Eduardo Anguita; Jim Hughes; Veronica Buckle; Francisco J Iborra; David Garrick; William G Wood
How transcriptional and epigenetic programmes are played out on an individual mammalian gene cluster during lineage commitment and differentiation.
Biochemical Society symposium 2006;(73):11-22.
2005: Sunitha N Wickramasinghe; William G Wood
Advances in the understanding of the congenital dyserythropoietic anaemias.
British journal of haematology 2005;131(4):431-46.
2005: Anuja Premawardhena; Christopher A Fisher; Nancy F Olivieri; Shanthimala de Silva; Jacqueline A Sloane-Stanley; William G Wood; David J Weatherall
A novel molecular basis for beta thalassemia intermedia poses new questions about its pathophysiology.
Blood 2005;106(9):3251-5.
2004: Eduardo Anguita; Jim Hughes; Clare Heyworth; Gerd A Blobel; William G Wood; Douglas R Higgs
Globin gene activation during haemopoiesis is driven by protein complexes nucleated by GATA-1 and GATA-2.
The EMBO journal 2004;23(14):2841-52.
2003: Richard J Gibbons; Andrea Pellagatti; David Garrick; William G Wood; Nicola Malik; Helena Ayyub; Cordelia Langford; Jacqueline Boultwood; james wainscoat; Douglas R Higgs
Identification of acquired somatic mutations in the gene encoding chromatin-remodeling factor ATRX in the alpha-thalassemia myelodysplasia syndrome (ATMDS).
Nature genetics 2003;34(4):446-9.
2003: Cristina Tufarelli; Jackie A Sloane Stanley; David Garrick; Jacqueline A Sharpe; Helena Ayyub; William G Wood; Douglas R Higgs
Transcription of antisense RNA leading to gene silencing and methylation as a novel cause of human genetic disease.
Nature genetics 2003;34(2):157-65.
2002: Eduardo Anguita; Jacqueline A Sharpe; Jacqueline A Sloane-Stanley; Cristina Tufarelli; Douglas R Higgs; William G Wood
Deletion of the mouse alpha-globin regulatory element (HS -26) has an unexpectedly mild phenotype.
Blood 2002;100(10):3450-6.
2001: Eduardo Anguita; C A Johnson; William G Wood; B M Turner; Douglas R Higgs
Identification of a conserved erythroid specific domain of histone acetylation across the alpha-globin gene cluster.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(21):12114-9.
2000: L Pritchard; Jacqueline A Sloane-Stanley; Jacqueline A Sharpe; R Aspinwall; W Lu; Veronica Buckle; Lana Strmecki; D Walker; Christopher J Ward; C E Alpers; J Zhou; William G Wood; Peter C Harris
A human PKD1 transgene generates functional polycystin-1 in mice and is associated with a cystic phenotype.
Human molecular genetics 2000;9(18):2617-27.
2000: V M Barbour; Cristina Tufarelli; Jacqueline A Sharpe; Z E Smith; Helena Ayyub; C A Heinlein; Jacqueline A Sloane-Stanley; K Indrak; William G Wood; Douglas R Higgs
alpha-thalassemia resulting from a negative chromosomal position effect.
Blood 2000;96(3):800-7.
1999: A M Thomson; Nigel A Roberts; Jacqueline A Sloane-Stanley; M Souyri; William G Wood
Haemopoietic progenitor cell lines generated by the myeloproliferative leukaemia virus: a model system to analyse murine and human lineage-affiliated genes.
British journal of haematology 1999;107(1):33-48.
1999: P Joy Ho; Jacqueline A Sloane-Stanley; A Athanassiadou; William G Wood; Swee Lay Thein
An in vitro system for expression analysis of mutations of the beta-globin gene: validation and application to two mutations in the 5' UTR.
British journal of haematology 1999;106(4):938-47.
1998: P Joy Ho; Georgina W Hall; S Watt; N C West; J W Wimperis; William G Wood; Swee Lay Thein
Unusually severe heterozygous beta-thalassemia: evidence for an interacting gene affecting globin translation.
Blood 1998;92(9):3428-35.
1998: A M Thomson; Nigel A Roberts; William G Wood
Bb1-3, a transgenic hybrid cell line with erythroid and megakaryocytic differentiation potential that expresses high levels of human gamma-globin and human beta-globin.
British journal of haematology 1998;102(4):976-85.
1998: Douglas R Higgs; Jacqueline A Sharpe; William G Wood
Understanding alpha globin gene expression: a step towards effective gene therapy.
Seminars in hematology 1998;35(2):93-104.
1997: Nigel A Roberts; Jacqueline A Sloane-Stanley; Jacqueline A Sharpe; S J Stanworth; William G Wood
Globin gene switching in transgenic mice carrying HS2-globin gene constructs.
Blood 1997;89(2):713-23.
1996: M D Pondel; Jacqueline A Sharpe; S Clark; L Pearson; William G Wood; Nick J Proudfoot
Proximal promoter elements of the human zeta-globin gene confer embryonic-specific expression on a linked reporter gene in transgenic mice.
Nucleic acids research 1996;24(21):4158-64.
1996: S J Stanworth; Nigel A Roberts; Jacqueline A Sharpe; William G Wood
Gene expression in somatic cell hybrids derived from embryonic mice transgenic for human globin genes.
British journal of haematology 1996;94(4):631-8.
1996: William G Wood
The complexities of beta globin gene regulation.
Trends in genetics : TIG 1996;12(6):204-6.
1995: S J Stanworth; Nigel A Roberts; Jacqueline A Sharpe; Jacqueline A Sloane-Stanley; William G Wood
Established epigenetic modifications determine the expression of developmentally regulated globin genes in somatic cell hybrids.
Molecular and cellular biology 1995;15(8):3969-78.
1995: G Gourdon; Jacqueline A Sharpe; Douglas R Higgs; William G Wood
The mouse alpha-globin locus regulatory element.
Blood 1995;86(2):766-75.
1995: Charles Craddock; P Vyas; Jacqueline A Sharpe; H Ayyub; William G Wood; Douglas R Higgs
Contrasting effects of alpha and beta globin regulatory elements on chromatin structure may be related to their different chromosomal environments.
The EMBO journal 1995;14(8):1718-26.
1994: G Gourdon; Jacqueline A Sharpe; D Wells; William G Wood; Douglas R Higgs
Analysis of a 70 kb segment of DNA containing the human zeta and alpha-globin genes linked to their regulatory element (HS-40) in transgenic mice.
Nucleic acids research 1994;22(20):4139-47.
1994: Jonathan Flint; Charles Craddock; A Villegas; D P Bentley; H J Williams; R Galanello; A Cao; William G Wood; H Ayyub; Douglas R Higgs
Healing of broken human chromosomes by the addition of telomeric repeats.
American journal of human genetics 1994;55(3):505-12.
1993: Jacqueline A Sharpe; D J Wells; E Whitelaw; P Vyas; Douglas R Higgs; William G Wood
Analysis of the human alpha-globin gene cluster in transgenic mice.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(23):11262-6.
1993: Jacqueline A Sharpe; R J Summerhill; P Vyas; G Gourdon; Douglas R Higgs; William G Wood
Role of upstream DNase I hypersensitive sites in the regulation of human alpha globin gene expression.
Blood 1993;82(5):1666-71.
1993: Swee Lay Thein; William G Wood; S N Wickramasinghe; M C Galvin
Beta-thalassemia unlinked to the beta-globin gene in an English family.
Blood 1993;82(3):961-7.
1993: J Lamb; Peter C Harris; Andrew O M Wilkie; William G Wood; J G Dauwerse; Douglas R Higgs
De novo truncation of chromosome 16p and healing with (TTAGGG)n in the alpha-thalassemia/mental retardation syndrome (ATR-16).
American journal of human genetics 1993;52(4):668-76.
1993: William G Wood
Increased HbF in adult life.
Baillière's clinical haematology 1993;6(1):177-213.
1992: Jacqueline A Sharpe; P S Chan-Thomas; J Lida; H Ayyub; William G Wood; Douglas R Higgs
Analysis of the human alpha globin upstream regulatory element (HS-40) in transgenic mice.
The EMBO journal 1992;11(12):4565-72.
1992: P Vyas; Jacqueline A Sharpe; P Watt; Douglas R Higgs; William G Wood
Regulation of human embryonic globin genes zeta 2 and epsilon in stably transformed mouse erythroleukemia cells.
Blood 1992;80(7):1832-7.
1992: B J Morley; C A Abbott; Jacqueline A Sharpe; J Lida; P S Chan-Thomas; William G Wood
A single beta-globin locus control region element (5' hypersensitive site 2) is sufficient for developmental regulation of human globin genes in transgenic mice.
Molecular and cellular biology 1992;12(5):2057-66.
1991: B J Morley; C A Abbott; William G Wood
Regulation of human fetal and adult globin genes in mouse erythroleukemia cells.
Blood 1991;78(5):1355-63.
1991: A P Jarman; William G Wood; Jacqueline A Sharpe; G Gourdon; H Ayyub; Douglas R Higgs
Characterization of the major regulatory element upstream of the human alpha-globin gene cluster.
Molecular and cellular biology 1991;11(9):4679-89.
1990: Douglas R Higgs; William G Wood; A P Jarman; J Sharpe; J Lida; I M Pretorius; H Ayyub
A major positive regulatory region located far upstream of the human alpha-globin gene locus.
Genes & development 1990;4(9):1588-601.
1990: C S Hatton; Andrew O M Wilkie; H C Drysdale; William G Wood; M A Vickers; J Sharpe; H Ayyub; I M Pretorius; V J Buckle; Douglas R Higgs
Alpha-thalassemia caused by a large (62 kb) deletion upstream of the human alpha globin gene cluster.
Blood 1990;76(1):221-7.
1990: Swee Lay Thein; C Hesketh; P Taylor; I J Temperley; R M Hutchinson; J M Old; William G Wood; John B Clegg; David J Weatherall
Molecular basis for dominantly inherited inclusion body beta-thalassemia.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(10):3924-8.
1990: Douglas R Higgs; William G Wood; A P Jarman; M A Vickers; Andrew O M Wilkie; J Lamb; P Vyas; J P Bennett
The alpha-thalassemias.
Annals of the New York Academy of Sciences 1990;612():15-22.