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Paul Brenchley

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Chemicals & Drugs

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Physiology

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Leukocytes, Mononuclear

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TOP 3
Alastair J Hutchison; Craig P Smith; Paul E C Brenchley
Pharmacology, efficacy and safety of oral phosphate binders.
Angela M Summers; Alferso C Abrahams; M Dominik Alscher; Michiel Betjes; Elisabeth Wilhelmina Boeschoten; Niko Braun; Paul E C Brenchley; Simon Davies; Louese Dunn; Lyda Engelsman; Marien Fieren; Guido Garosi; Eric Goffin; Lara Heuveling; Mario Korte; Bengt Lindholm; Peter Rutherford; Dirk Struijk; Marion Verduijn; Christian Verger; Ralf Westerhuis
A collaborative approach to understanding EPS: the European perspective.
Amanda J Churchill; James G Carter; Conor Ramsden; Steven J Turner; Anna Yeung; Paul E C Brenchley; David W Ray
VEGF polymorphisms are associated with severity of diabetic retinopathy.

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All Publications

2011: Alastair J Hutchison; Craig P Smith; Paul E C Brenchley
Pharmacology, efficacy and safety of oral phosphate binders.
Nature reviews. Nephrology 2011;7(10):578-89.
2011: Angela M Summers; Alferso C Abrahams; M Dominik Alscher; Michiel Betjes; Elisabeth Wilhelmina Boeschoten; Niko Braun; Paul E C Brenchley; Simon Davies; Louese Dunn; Lyda Engelsman; Marien Fieren; Guido Garosi; Eric Goffin; Lara Heuveling; Mario Korte; Bengt Lindholm; Peter Rutherford; Dirk Struijk; Marion Verduijn; Christian Verger; Ralf Westerhuis
A collaborative approach to understanding EPS: the European perspective.
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 2011;31(3):245-8.
2008: Amanda J Churchill; James G Carter; Conor Ramsden; Steven J Turner; Anna Yeung; Paul E C Brenchley; David W Ray
VEGF polymorphisms are associated with severity of diabetic retinopathy.
Investigative ophthalmology & visual science 2008;49(8):3611-6.
2008: Declan de Freitas; Antoinette Jordaan; Rosalind Williams; Jane Alderdice; Janet Curwell; Helen Hurst; Alastair J Hutchison; Paul E C Brenchley; Titus Augustine; Angela M Summers
Nutritional management of patients undergoing surgery following diagnosis with encapsulating peritoneal sclerosis.
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 2008;28(3):271-6.
2008: Mark Robert Dilworth; Marc J Clancy; Damian Marshall; Christopher A Bravery; Paul E C Brenchley; Nick Ashton
Development and functional capacity of transplanted rat metanephroi.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2008;23(3):871-9.
2007: Shirley Ralph; Paul E C Brenchley; Angela Summers; Daniela D Rosa; Ric Swindell; Gordon C Jayson
Heparanase gene haplotype (CGC) is associated with stage of disease in patients with ovarian carcinoma.
Cancer science 2007;98(6):844-9.
2007: Shelley Harris; Beatrice M Coupes; Stephen A Roberts; Ian S D Roberts; colin short; Paul E C Brenchley
TGF-beta1 in chronic allograft nephropathy following renal transplantation.
Journal of nephrology 2007;20(2):177-85.
2007: A Jordaan; Declan de Freitas; H Hurst; J Alderdice; J Curwell; Paul E C Brenchley; Alastair J Hutchison; Angela M Summers
Malnutrition and refeeding syndrome associated with encapsulating peritoneal sclerosis.
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 2007;27(1):100-1.
2006: Tibor Kovács; Shelley Harris; Tibor K Vas; Ildikó Seres; colin short; István Wittmann; György Paragh; Michael I Mackness; Bharti Mackness; Paul N Durrington; Judit M Nagy; Paul E C Brenchley
Paraoxonase gene polymorphism and serum activity in progressive IgA nephropathy.
Journal of nephrology 2006;19(6):732-8.
2006: Paul E C Brenchley; Bengt Lindholm; Friedo W Dekker; gerjan navis
Translating knowledge of the human genome into clinical practice in nephrology dialysis and transplantation: the renal genome network (ReGeNet).
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2006;21(10):2681-3.
2006: Angela M Summers; Paul E C Brenchley
An international encapsulating peritoneal sclerosis registry and DNA bank: why we need one now.
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 2006;26(5):559-63.
2006: Rasheed A Gbadegesin; SA Cotton; C J Watson; Paul E C Brenchley; Nicholas J A Webb
Association between ICAM-1 Gly-Arg polymorphism and renal parenchymal scarring following childhood urinary tract infection.
International journal of immunogenetics 2006;33(1):49-53.
2006: Helen S Young; Angela M Summers; Ian R Read; David A Fairhurst; Darren Plant; Emanuela Campalani; Catherine H Smith; J N W N Barker; Michael Detmar; Paul E C Brenchley; Christopher E M Griffiths
Interaction between genetic control of vascular endothelial growth factor production and retinoid responsiveness in psoriasis.
The Journal of investigative dermatology 2006;126(2):453-9.
2006: Michelle Jackson; Yasmeen Ahmad; Ian N Bruce; Beatrice M Coupes; Paul E C Brenchley
Activation of transforming growth factor-beta1 and early atherosclerosis in systemic lupus erythematosus.
Arthritis research & therapy 2006;8(3):R81.
2005: Angela M Summers; Marc J Clancy; Fysal Syed; Nicola Harwood; Paul E C Brenchley; Titus Augustine; Hany Riad; Alastair J Hutchison; Paul Taylor; Robert Pearson; Ram Gokal
Single-center experience of encapsulating peritoneal sclerosis in patients on peritoneal dialysis for end-stage renal failure.
Kidney international 2005;68(5):2381-8.
2005: Angela M Summers; Beatrice M Coupes; Mary Frances Brennan; Shirley A Ralph; colin short; Paul E C Brenchley
VEGF -460 genotype plays an important role in progression to chronic kidney disease stage 5.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2005;20(11):2427-32.
2005: Olukemi Amodu; Rasheed A Gbadegesin; S A Ralph; Adebowale Adeyemo; Paul E C Brenchley; Omolola O Ayoola; Adebola Emmanuel Orimadegun; AK Akinsola; PE Olumese; Olayemi O Omotade
Plasmodium falciparum malaria in south-west Nigerian children: is the polymorphism of ICAM-1 and E-selectin genes contributing to the clinical severity of malaria?
Acta tropica 2005;95(3):248-55.
2005: D Marshall; Marc J Clancy; MJ Bottomley; K Symonds; Paul E C Brenchley; Christopher A Bravery
Transplantation of metanephroi to sites within the abdominal cavity.
Transplantation proceedings 2005;37(1):194-7.
2005: Richard C L Holt; Nicholas J A Webb; Shirley A Ralph; John Davies; colin short; Paul E C Brenchley
Heparanase activity is dysregulated in children with steroid-sensitive nephrotic syndrome.
Kidney international 2005;67(1):122-9.
2004: Xiaotong He; Paul E C Brenchley; Gordon C Jayson; Lynne Hampson; John Davies; Ian N Hampson
Hypoxia increases heparanase-dependent tumor cell invasion, which can be inhibited by antiheparanase antibodies.
Cancer research 2004;64(11):3928-33.
2004: David Ray; Manoj Mishra; Shirley Ralph; Ian Read; Robert Davies; Paul E C Brenchley
Association of the VEGF gene with proliferative diabetic retinopathy but not proteinuria in diabetes.
Diabetes 2004;53(3):861-4.
2004: Helen S Young; Angela M Summers; Monica Bhushan; Paul E C Brenchley; Christopher E M Griffiths
Single-nucleotide polymorphisms of vascular endothelial growth factor in psoriasis of early onset.
The Journal of investigative dermatology 2004;122(1):209-15.
2004: Nicholas J A Webb; Paul E C Brenchley
Cytokines and cell adhesion molecules in the inflammatory response during acute pyelonephritis.
Nephron. Experimental nephrology 2004;96(1):e1-6.
2003: Farhad Behzad; Paul E C Brenchley
A multiwell format assay for heparanase.
Analytical biochemistry 2003;320(2):207-13.
2003: Paul E C Brenchley
Vascular permeability factors in steroid-sensitive nephrotic syndrome and focal segmental glomerulosclerosis.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2003;18 Suppl 6():vi21-5.
2003: D C Cattran; R Wald; Paul E C Brenchley; Beatrice M Coupes
Clinical correlates of serial urinary membrane attack complex estimates in patients with idiopathic membranous nephropathy.
Clinical nephrology 2003;60(1):7-12.
2003: Adam Stevens; Joanne Soden; Paul E C Brenchley; Shirley Ralph; David W Ray
Haplotype analysis of the polymorphic human vascular endothelial growth factor gene promoter.
Cancer research 2003;63(4):812-6.
2003: Richard C L Holt; Shirley A Ralph; Nicholas J A Webb; C J Watson; A G B Clark; P W Mathieson; Paul E C Brenchley
Steroid-sensitive nephrotic syndrome and vascular endothelial growth factor gene polymorphisms.
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics 2003;30(1):1-3.
2002: Monica Bhushan; Helen S Young; Paul E C Brenchley; Christopher E M Griffiths
Recent advances in cutaneous angiogenesis.
The British journal of dermatology 2002;147(3):418-25.
2002: Emma A O Shittu; Chun-Ping Yang; Ian S D Roberts; Eric B Bell; Paul E C Brenchley; Trudie Roberts; Peter J Wood
Inhibition of chronic vascular rejection by donor-specific blood transfusion is associated with a reduction in transforming growth factor-beta1 expression.
Transplantation 2002;73(10):1573-81.
2002: Rasheed A Gbadegesin; C J Watson; SA Cotton; Paul E C Brenchley; Nicholas J A Webb
A PCR-RFLP typing method for adhesion molecule gene polymorphisms and allele frequencies in a normal UK population.
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics 2002;29(2):109-11.
2002: Rasheed A Gbadegesin; SA Cotton; Beatrice M Coupes; A Awan; Paul E C Brenchley; Nicholas J A Webb
Plasma and urinary soluble adhesion molecule expression is increased during first documented acute pyelonephritis.
Archives of disease in childhood 2002;86(3):218-21.
2002: Shirley A Cotton; Rasheed A Gbadegesin; Shelley Williams; Paul E C Brenchley; Nicholas J A Webb
Role of TGF-beta1 in renal parenchymal scarring following childhood urinary tract infection.
Kidney international 2002;61(1):61-7.
2001: Paul E C Brenchley
Antagonising angiogenesis in rheumatoid arthritis.
Annals of the rheumatic diseases 2001;60 Suppl 3():iii71-4.
2001: I H Chaudhry; D G O'Donovan; Paul E C Brenchley; Helen Reid; Ian S D Roberts
Vascular endothelial growth factor expression correlates with tumour grade and vascularity in gliomas.
Histopathology 2001;39(4):409-15.
2001: AC Allen; EM Bailey; Paul E C Brenchley; KS Buck; Jonathan Barratt; John Feehally
Mesangial IgA1 in IgA nephropathy exhibits aberrant O-glycosylation: observations in three patients.
Kidney international 2001;60(3):969-73.
2001: Paul E C Brenchley; S Williams; Beatrice M Coupes; colin short
Strategies for meaningful measurement of circulating levels of transforming growth factor beta1 in clinical samples.
Transplantation 2001;71(9):1355-6.
2001: Beatrice M Coupes; S Williams; Ian S D Roberts; colin short; Paul E C Brenchley
Plasma transforming growth factor beta(1) and platelet activation: implications for studies in transplant recipients.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2001;16(2):361-7.
2000: CJ Watson; Nicholas J A Webb; MJ Bottomley; Paul E C Brenchley
Identification of polymorphisms within the vascular endothelial growth factor (VEGF) gene: correlation with variation in VEGF protein production.
Cytokine 2000;12(8):1232-5.
2000: MJ Bottomley; Nicholas J A Webb; CJ Watson; L Holt; Marwan Bukhari; J Denton; Anthony J Freemont; Paul E C Brenchley
Placenta growth factor (PlGF) induces vascular endothelial growth factor (VEGF) secretion from mononuclear cells and is co-expressed with VEGF in synovial fluid.
Clinical and experimental immunology 2000;119(1):182-8.
1999: E Bailey; MJ Bottomley; S Westwell; James Pringle; Peter N Furness; John Feehally; Paul E C Brenchley; SJ Harper
Vascular endothelial growth factor mRNA expression in minimal change, membranous, and diabetic nephropathy demonstrated by non-isotopic in situ hybridisation.
Journal of clinical pathology 1999;52(10):735-8.
1999: MJ Bottomley; Nicholas J A Webb; CJ Watson; P J Holt; Anthony J Freemont; Paul E C Brenchley
Peripheral blood mononuclear cells from patients with rheumatoid arthritis spontaneously secrete vascular endothelial growth factor (VEGF): specific up-regulation by tumour necrosis factor-alpha (TNF-alpha) in synovial fluid.
Clinical and experimental immunology 1999;117(1):171-6.
1999: Nicholas J A Webb; C J Watson; I S Roberts; MJ Bottomley; C A Jones; Malcolm A Lewis; Robert J Postlethwaite; Paul E C Brenchley
Circulating vascular endothelial growth factor is not increased during relapses of steroid-sensitive nephrotic syndrome.
Kidney international 1999;55(3):1063-71.
1998: Nicholas J A Webb; MJ Bottomley; CJ Watson; Paul E C Brenchley
Vascular endothelial growth factor (VEGF) is released from platelets during blood clotting: implications for measurement of circulating VEGF levels in clinical disease.
Clinical science (London, England : 1979) 1998;94(4):395-404.
1998: Nicholas J A Webb; C R Myers; CJ Watson; MJ Bottomley; Paul E C Brenchley
Activated human neutrophils express vascular endothelial growth factor (VEGF).
Cytokine 1998;10(4):254-7.
1998: Paul E C Brenchley; colin short; Ian S D Roberts
Is persistent TGFbeta1 expression the mechanism responsible for chronic renal allograft loss?
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 1998;13(3):548-51.
1997: N P Mallick; Paul E C Brenchley; Nicholas J A Webb
Minimal change nephropathy and focal segmental glomerulosclerosis.
Kidney international. Supplement 1997;58():S80-2.
1996: S C Grant; S P Guy; W R Lamb; Nicholas H Brooks; Paul E C Brenchley; Ian Hutchinson
Expression of cytokine messenger RNA after heart transplantation: relationship with rejection and serum cytokines.
Transplantation 1996;62(7):910-6.
1996: N P Mallick; colin short; Paul E C Brenchley; N Webb
Recent approaches to understanding clinical glomerular disease.
Renal failure 1996;18(5):705-9.
1996: S C Grant; W R Lamb; Nicholas H Brooks; Paul E C Brenchley; Ian Hutchinson
Serum cytokines in human heart transplant recipients. Is there a relationship to rejection?
Transplantation 1996;62(4):480-91.
1996: N Anwar; A J Hutchison; J Manos; Linda Uttley; Paul E C Brenchley; Ram Gokal
Peritoneal dialysate IgG/C3 levels do not predict susceptibility to peritonitis.
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 1996;16(2):154-7.
1995: S P Kon; B Coupes; colin short; L R Solomon; Martin J Raftery; Netar Mallick; Paul E C Brenchley
Urinary C5b-9 excretion and clinical course in idiopathic human membranous nephropathy.
Kidney international 1995;48(6):1953-8.
1995: DM Turner; S C Grant; W R Lamb; Paul E C Brenchley; Philip A Dyer; PJ Sinnott; Ian Hutchinson
A genetic marker of high TNF-alpha production in heart transplant recipients.
Transplantation 1995;60(10):1113-7.
1995: S C Grant; W R Lamb; N Yonan; Ian Hutchinson; Paul E C Brenchley
Antithymocyte globulin preparations after heart transplantation. Cytokine responses in vivo and in vitro.
Transplantation 1995;60(7):684-9.
1995: J V Joseph; S P Guy; Paul E C Brenchley; Neil Parrott; colin short; R W G Johnson; Ian Hutchinson
Th1 and Th2 cytokine gene expression in human renal allografts.
Transplantation proceedings 1995;27(1):915-6.
1994: S C Grant; W R Lamb; Ian Hutchinson; Paul E C Brenchley
Serum soluble adhesion molecules and cytokines in cardiac allograft rejection. The Manchester Transplant Cytokine Group.
Transplant immunology 1994;2(4):321-5.
1994: N Snowden; B Coupes; Ariane L Herrick; K Illingworth; Malcolm Jayson; Paul E C Brenchley
Plasma TGF beta in systemic sclerosis: a cross-sectional study.
Annals of the rheumatic diseases 1994;53(11):763-7.
1994: B M Coupes; C G Newstead; colin short; Paul E C Brenchley
Transforming growth factor beta 1 in renal allograft recipients.
Transplantation 1994;57(12):1727-31.
1993: R C Chasty; W R Lamb; H Gallati; Trudie Roberts; Paul E C Brenchley; John A Liu Yin
Serum cytokine levels in patients undergoing bone marrow transplantation.
Bone marrow transplantation 1993;12(4):331-6.
1993: C G Newstead; W R Lamb; Paul E C Brenchley; colin short
Serum and urine IL-6 and TNF-alpha in renal transplant recipients with graft dysfunction.
Transplantation 1993;56(4):831-5.
1993: B A Foëx; W R Lamb; Trudie Roberts; S G Brear; I Macartney; M Hammer; Paul E C Brenchley
Early cytokine response to multiple injury.
Injury 1993;24(6):373-6.
1993: B M Coupes; S P Kon; Paul E C Brenchley; colin short; Netar Mallick
The temporal relationship between urinary C5b-9 and C3dg and clinical parameters in human membranous nephropathy.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 1993;8(5):397-401.
1992: W R Lamb; Richard S H Pumphrey; Paul E C Brenchley
A peroxidase-linked enzyme immunoassay for tumour necrosis factor alpha utilising alternative colorimetric or chemilumimetric substrates.
Journal of immunological methods 1992;155(2):215-23.
1992: Paul E C Brenchley; B Coupes; colin short; D J O'Donoghue; F W Ballardie; Netar Mallick
Urinary C3dg and C5b-9 indicate active immune disease in human membranous nephropathy.
Kidney international 1992;41(4):933-7.
1992: B Coupes; Paul E C Brenchley; colin short; Netar Mallick
Clinical aspects of C3dg and C5b-9 in human membranous nephropathy.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 1992;7 Suppl 1():32-4.
1992: Paul E C Brenchley; colin short; J Feehally; Netar Mallick
Towards defining antigens in human membranous nephropathy.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 1992;7 Suppl 1():21-4.
1991: W R Lamb; Paul E C Brenchley; K J Wood; Richard S H Pumphrey
C-reactive protein levels in serum: a rapid enzyme immunoassay.
Medical laboratory sciences 1991;48(3):201-5.
1991: S Martin; Paul E C Brenchley; Robert J Postlethwaite; R W Johnson; Philip A Dyer
Detection of anti-epithelial cell antibodies in association with pediatric renal transplant failure using a novel microcytotoxicity assay.
Tissue antigens 1991;37(4):152-5.
1990: R F Sewell; Paul E C Brenchley
Coupling of mono- and polyamino ligands to solid phases by nucleophilic attack on coupling groups that may be spontaneously hydrolysed.
Journal of chromatography 1990;525(1):246-8.
1989: R F Sewell; Paul E C Brenchley; N P Mallick
Human mononuclear cells contain an endoglycosidase specific for heparan sulphate glycosaminoglycan demonstrable with the use of a specific solid-phase metabolically radiolabelled substrate.
The Biochemical journal 1989;264(3):777-83.
1989: D J O'Donoghue; colin short; Paul E C Brenchley; W Lawler; F W Ballardie
Sequential development of systemic vasculitis with anti-neutrophil cytoplasmic antibodies complicating anti-glomerular basement membrane disease.
Clinical nephrology 1989;32(6):251-5.
1989: colin short; B M Coupes; Paul E C Brenchley; S Martin; S Williams; R W G Johnson; Netar Mallick; G Williams
Membranous nephropathy: monoclonal IgG and nephrotic-range proteinuria in a renal transplant recipient.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 1989;4(12):1080-2.
1988: F W Ballardie; Paul E C Brenchley; S Williams; D J O'Donoghue
Autoimmunity in IgA nephropathy.
Lancet 1988;2(8611):588-92.
1988: S Martin; Paul E C Brenchley; D J O'Donoghue; P A Dyer; Netar Mallick; R W G Johnson
The identification of allo- and auto-lymphocytotoxic antibodies in serum, in the presence of rabbit antithymocyte globulin.
Tissue antigens 1988;31(1):26-32.
1987: J Feehally; T J Beattie; Paul E C Brenchley; B M Coupes; Netar Mallick; Robert J Postlethwaite
Response of circulating immune complexes to food challenge in relapsing IgA nephropathy.
Pediatric nephrology (Berlin, Germany) 1987;1(4):581-6.
1986: J Feehally; T J Beattie; Paul E C Brenchley; B M Coupes; Netar Mallick; Robert J Postlethwaite
Sequential study of the IgA system in relapsing IgA nephropathy.
Kidney international 1986;30(6):924-31.
1986: P B Wilson; K J Wood; P Doré; J A Swainson; Paul E C Brenchley; Richard S H Pumphrey
Investigation of IgG4 levels in atopic patients using a competitive inhibition assay employing biotinylated IgG4 myeloma and avidin peroxidase.
Journal of immunological methods 1986;87(1):59-67.
1986: J Feehally; Paul E C Brenchley; B M Coupes; Netar Mallick; D M Morris; colin short
Impaired IgG response to tetanus toxoid in human membranous nephropathy: association with HLA-DR3.
Clinical and experimental immunology 1986;63(2):376-84.
1984: J Feehally; T J Beattie; Paul E C Brenchley; B M Coupes; I B Houston; N P Mallick; R J Postlethwaite
Modulation of cellular immune function by cyclophosphamide in children with minimal-change nephropathy.
The New England journal of medicine 1984;310(7):415-20.
1983: Paul E C Brenchley; J Feehally; P Doré; B Coupes; colin short; Richard S H Pumphrey; N P Mallick
Gm allotypes in membranous nephropathy.
The New England journal of medicine 1983;309(9):556-7.