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Klaus Brendel

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TOP 3
Milos Chvapil; Filip Kielar; Frantisek Liska; Alexandra Silhankova; Klaus Brendel
Synthesis and evaluation of long-acting D-penicillamine derivatives.
Jeffrey M Catania; Alan R Parrish; Donald Kirkpatrick; M Chitkara; George Bowden; Colin Henderson; C R Wolf; A J Clark; Klaus Brendel; Robyn L Fisher; A Gandolfi
Precision-cut tissue slices from transgenic mice as an in vitro toxicology system.
Robyn L Fisher; A Gandolfi; Klaus Brendel
Human liver quality is a dominant factor in the outcome of in vitro studies.

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All Publications

2005: Milos Chvapil; Filip Kielar; Frantisek Liska; Alexandra Silhankova; Klaus Brendel
Synthesis and evaluation of long-acting D-penicillamine derivatives.
Connective tissue research 2005;46(4-5):242-50.
2003: Jeffrey M Catania; Alan R Parrish; Donald Kirkpatrick; M Chitkara; George Bowden; Colin Henderson; C R Wolf; A J Clark; Klaus Brendel; Robyn L Fisher; A Gandolfi
Precision-cut tissue slices from transgenic mice as an in vitro toxicology system.
Toxicology in vitro : an international journal published in association with BIBRA 2003;17(2):201-5.
2001: Robyn L Fisher; A Gandolfi; Klaus Brendel
Human liver quality is a dominant factor in the outcome of in vitro studies.
Cell biology and toxicology 2001;17(3):179-89.
2000: V Sinha; Klaus Brendel; Michael Mayersohn
A simplified isolated perfused rat liver apparatus: characterization and measurement of extraction ratios of selected compounds.
Life sciences 2000;66(19):1795-804.
1998: Alan R Parrish; R Fisher; Christopher M Bral; Robert C. Burghardt; A Gandolfi; Klaus Brendel; Kenneth S Ramos
Benzo(a)pyrene-induced alterations in growth-related gene expression and signaling in precision-cut adult rat liver and kidney slices.
Toxicology and applied pharmacology 1998;152(2):302-8.
1998: S J Hasal; Y Sun; CC Yan; Klaus Brendel; RJ Huxtable
Effects of taurine in precision-cut liver slices exposed to the pyrrolizidine alkaloid retrorsine.
Advances in experimental medicine and biology 1998;442():79-83.
1998: Y Sun; S J Hasal; CC Yan; Klaus Brendel; RJ Huxtable
Pyrrolizidine alkaloid-induced depletion of taurine from rat liver in vivo and in vitro.
Advances in experimental medicine and biology 1998;442():71-7.
1997: Alison E M Vickers; R M Jimenez; M C Spaans; V Pflimlin; Robyn L Fisher; Klaus Brendel
Human and rat lung biotransformation of cyclosporin A and its derivatives using slices and bronchial epithelial cells.
Drug metabolism and disposition: the biological fate of chemicals 1997;25(7):873-80.
1996: J B Wueweera; A Gandolfi; D A Badger; I Glenn Sipes; Klaus Brendel
Vitamin A potentiation of vinylidene chloride hepatotoxicity in rats and precision-cut rat liver slices.
Fundamental and applied toxicology : official journal of the Society of Toxicology 1996;34(1):73-83.
1996: R L Fisher; S J Hasal; J T Sanuik; K S Hasal; A Gandolfi; Klaus Brendel
Cold- and cryopreservation of dog liver and kidney slices.
Cryobiology 1996;33(1):163-71.
1996: A Gandolfi; J Wijeweera; Klaus Brendel
Use of precision-cut liver slices as an in vitro tool for evaluating liver function.
Toxicologic pathology 1996;24(1):58-61.
1995: A Gandolfi; Klaus Brendel; R L Fisher; J P Michaud
Use of tissue slices in chemical mixture toxicology and interspecies investigations.
Toxicology 1995;105(2-3):285-90.
1995: J B Wijeweera; C M Thomas; A Gandolfi; Klaus Brendel
Sodium arsenite and heat shock induce stress proteins in precision-cut rat liver slices.
Toxicology 1995;104(1-3):35-45.
1995: R L Fisher; S J Hasal; I Glenn Sipes; A Gandolfi; Klaus Brendel
Comparative metabolism and toxicity of dichlorobenzenes in Sprague-Dawley, Fischer-344 and human liver slices.
Human & experimental toxicology 1995;14(5):414-21.
1995: A K Payne; S E Morgan; A Gandolfi; Klaus Brendel
Biotransformation of sevoflurane by rat neonate liver slices.
Drug metabolism and disposition: the biological fate of chemicals 1995;23(4):497-500.
1995: C A Burton; K Hatlelid; K Divine; Dean E Carter; Quintus Fernando; Klaus Brendel; A Gandolfi
Glutathione effects on toxicity and uptake of mercuric chloride and sodium arsenite in rabbit renal cortical slices.
Environmental health perspectives 1995;103 Suppl 1():81-4.
1995: A R Parrish; A Gandolfi; Klaus Brendel
Precision-cut tissue slices: applications in pharmacology and toxicology.
Life sciences 1995;57(21):1887-901.
1994: H V Sheevers; Klaus Brendel; Stephen H Wright; Raymond B Nagle; A Gandolfi
Nephrotoxicity and uptake of 1-benzyl quinolinium in precision-cut rabbit renal cortical slices.
Toxicology in vitro : an international journal published in association with BIBRA 1994;8(6):1243-51.
1994: Alan R Parrish; R T Dorr; A Gandolfi; Klaus Brendel
Adult rat myocardial slices: A tool for studies of comparative cardiotoxicity.
Toxicology in vitro : an international journal published in association with BIBRA 1994;8(6):1233-7.
1994: R L Fisher; J T Sanuik; A Gandolfi; Klaus Brendel
Toxicity of cisplatin and mercuric chloride in human kidney cortical slices.
Human & experimental toxicology 1994;13(8):517-23.
1994: R L Fisher; M S Smith; S J Hasal; K S Hasal; A Gandolfi; Klaus Brendel
The use of human lung slices in toxicology.
Human & experimental toxicology 1994;13(7):466-71.
1994: Robyn L Fisher; J T Sanuik; H Nau; A Gandolfi; Klaus Brendel
Comparative toxicity of valproic acid and its metabolites in liver slices from adult rats, weanling rats and humans.
Toxicology in vitro : an international journal published in association with BIBRA 1994;8(3):371-9.
1994: T S Poet; Klaus Brendel; James Halpert
Inactivation of cytochromes P450 2B protects against cocaine-mediated toxicity in rat liver slices.
Toxicology and applied pharmacology 1994;126(1):26-32.
1994: S Azri-Meehan; H P Mata; A Gandolfi; Klaus Brendel
The interactive toxicity of CHCl3 and BrCCl3 in precision-cut rat liver slices.
Fundamental and applied toxicology : official journal of the Society of Toxicology 1994;22(2):172-7.
1994: J P Michaud; A Gandolfi; Klaus Brendel
Toxic responses to defined chemical mixtures: mathematical models and experimental designs.
Life sciences 1994;55(9):635-51.
1994: J S Sawyer; J A Daller; Klaus Brendel; K Yohem; C W Putnam
The hepatotoxicities of endotoxin and ethanol comparisons in vitro using the precision-cut rat liver slice model.
Life sciences 1994;55(18):1407-17.
1993: R Fisher; Klaus Brendel; R P Hanzlik
Correlation of metabolism, covalent binding and toxicity for a series of bromobenzene derivatives using rat liver slices in vitro.
Chemico-biological interactions 1993;88(2-3):191-8.
1993: R L Fisher; S J Hasal; J T Sanuik; K S Scott; A Gandolfi; Klaus Brendel
Cold- and cryopreservation of human liver and kidney slices.
Cryobiology 1993;30(3):250-61.
1993: R L Fisher; A Gandolfi; I Glenn Sipes; Klaus Brendel
Culture medium composition affects the relative toxicities of chlorobenzenes in rat liver slices and the isolated perfused liver.
Drug and chemical toxicology 1993;16(4):321-39.
1992: H N Ghantous; J Fernando; A Gandolfi; Klaus Brendel
Sevoflurane is biotransformed by guinea pig liver slices but causes minimal cytotoxicity.
Anesthesia and analgesia 1992;75(3):436-40.
1992: H N Ghantous; J L Fernando; R L Keith; A Gandolfi; Klaus Brendel
Effects of halothane and other volatile anaesthetics on protein synthesis and secretion in guinea pig liver slices.
British journal of anaesthesia 1992;68(2):172-7.
1992: S Azri; H P Mata; L L Reid; A Gandolfi; Klaus Brendel
Further examination of the selective toxicity of CCl4 in rat liver slices.
Toxicology and applied pharmacology 1992;112(1):81-6.
1992: A P Brown; Kenneth L Hastings; A Gandolfi; Daniel C Liebler; Klaus Brendel
Formation and identification of protein adducts to cytosolic proteins in guinea pig liver slices exposed to halothane.
Toxicology 1992;73(3):281-95.
1992: S Azri-Meehan; H P Mata; A Gandolfi; Klaus Brendel
The hepatotoxicity of chloroform in precision-cut rat liver slices.
Toxicology 1992;73(3):239-50.
1991: R Fisher; J Barr; C F Zukoski; C W Putnam; I Glenn Sipes; A Gandolfi; Klaus Brendel
In-vitro hepatotoxicity of three dichlorobenzene isomers in human liver slices.
Human & experimental toxicology 1991;10(5):357-63.
1991: H N Ghantous; J Fernando; A Gandolfi; Klaus Brendel
Minimal biotransformation and toxicity of desflurane in guinea pig liver slices.
Anesthesia and analgesia 1991;72(6):796-800.
1991: S M Wishnies; A R Parrish; I Glenn Sipes; A Gandolfi; C W Putnam; C L Krumdieck; Klaus Brendel
Biotransformation activity in vitrified human liver slices.
Cryobiology 1991;28(3):216-26.
1991: L Gunawardhana; J Barr; A J Weir; Klaus Brendel; I Glenn Sipes
The N-acetylation of sulfamethazine and p-aminobenzoic acid by human liver slices in dynamic organ culture.
Drug metabolism and disposition: the biological fate of chemicals 1991;19(3):648-54.
1991: R Fisher; C W Putnam; L J Koep; I G Sipes; A Gandolfi; Klaus Brendel
Cryopreservation of pig and human liver slices.
Cryobiology 1991;28(2):131-42.
1991: J Barr; A J Weir; Klaus Brendel; I Glenn Sipes
Liver slices in dynamic organ culture. II. An in vitro cellular technique for the study of integrated drug metabolism using human tissue.
Xenobiotica; the fate of foreign compounds in biological systems 1991;21(3):341-50.
1991: J Barr; A J Weir; Klaus Brendel; I Glenn Sipes
Liver slices in dynamic organ culture. I. An alternative in vitro technique for the study of rat hepatic drug metabolism.
Xenobiotica; the fate of foreign compounds in biological systems 1991;21(3):331-9.
1991: R Fisher; H Nau; A Gandolfi; Klaus Brendel
Toxicity of valproic acid in liver slices from sprague-dawley rats and domestic pigs.
Toxicology in vitro : an international journal published in association with BIBRA 1991;5(3):201-5.
1991: H Ghantous; J Fernando; A Gandolfi; Klaus Brendel
Inhibition of protein synthesis and secretion by volatile anesthetics in guinea pig liver slices.
Advances in experimental medicine and biology 1991;283():725-30.
1991: R Fisher; S McCarthy; I Glenn Sipes; R P Hanzlik; Klaus Brendel
Metabolism of dichlorobenzenes in organ cultured liver slices.
Advances in experimental medicine and biology 1991;283():717-23.
1991: A P Brown; Kenneth L Hastings; A Gandolfi; Klaus Brendel
Covalent binding of a halothane metabolite and neoantigen production in guinea pig liver slices.
Advances in experimental medicine and biology 1991;283():693-7.
1991: S Azri; H P Mata; A Gandolfi; Klaus Brendel
CCl4-induced cytochrome P-450 loss and lipid peroxidation in rat liver slices.
Advances in experimental medicine and biology 1991;283():669-74.
1991: R Fisher; H Nau; A Gandolfi; C W Putnam; Klaus Brendel
Valproic acid hepatotoxicity in human liver slices.
Drug and chemical toxicology 1991;14(4):375-94.
1990: H N Ghantous; J Fernando; A Gandolfi; Klaus Brendel
Biotransformation of halothane in guinea pig liver slices.
Drug metabolism and disposition: the biological fate of chemicals 1990;18(4):514-8.
1990: H N Ghantous; J Fernando; A Gandolfi; Klaus Brendel
Toxicity of halothane in guinea pig liver slices.
Toxicology 1990;62(1):59-69.
1990: Z W Li; W A Bijl; J W van Nispen; Klaus Brendel; Thomas P Davis
Neuropeptide processing in regional brain slices: effect of conformation and sequence.
The Journal of pharmacology and experimental therapeutics 1990;253(2):851-7.
1990: S Connors; D R Rankin; A Gandolfi; C L Krumdieck; L J Koep; Klaus Brendel
Cocaine hepatotoxicity in cultured liver slices: a species comparison.
Toxicology 1990;61(2):171-83.
1990: W Zheng; R M Maiorino; Klaus Brendel; H Vasken Aposhian
Determination and metabolism of dithiol chelating agents. VII. Biliary excretion of dithiols and their interactions with cadmium and metallothionein.
Fundamental and applied toxicology : official journal of the Society of Toxicology 1990;14(3):598-607.
1990: A Gandolfi; Klaus Brendel
In vitro systems for nephrotoxicity studies.
Toxicology in vitro : an international journal published in association with BIBRA 1990;4(4-5):337-45.
1990: G H Wolfgang; A Gandolfi; Raymond B Nagle; Klaus Brendel; James L Stevens
Assessment of S-(1,2-dichlorovinyl)-L-cysteine induced toxic events in rabbit renal cortical slices. Biochemical and histological evaluation of uptake, covalent binding, and toxicity.
Chemico-biological interactions 1990;75(2):153-70.
1989: G H Wolfgang; A Gandolfi; James L Stevens; Klaus Brendel
N-acetyl S-(1,2-dichlorovinyl)-L-cysteine produces a similar toxicity to S-(1,2-dichlorovinyl)-L-cysteine in rabbit renal slices: differential transport and metabolism.
Toxicology and applied pharmacology 1989;101(2):205-19.
1989: G H Wolfgang; A Gandolfi; James L Stevens; Klaus Brendel
In vitro and in vivo nephrotoxicity of the L and D isomers of S-(1,2-dichlorovinyl)-cysteine.
Toxicology 1989;58(1):33-42.
1989: G H Wolfgang; A Gandolfi; Klaus Brendel
Evaluation of organic nephrotoxins in rabbit renal cortical slices.
Toxicology in vitro : an international journal published in association with BIBRA 1989;3(4):341-50.
1989: S Conners; D R Rankin; C L Krumdieck; Klaus Brendel
Interactive toxicity of cocaine with phenobarbital, morphine and ethanol in organ cultured human and rat liver slices.
Proceedings of the Western Pharmacology Society 1989;32():205-8.
1988: R L McKee; Victor J Hruby; Dev Trivedi; D G Johnson; A Gandolfi; C L Krumdieck; Klaus Brendel
Perifused precision-cut liver slice system for the study of hormone-regulated hepatic glucose metabolism.
Journal of pharmacological methods 1988;19(4):339-54.
1988: O Dale; A Gandolfi; Klaus Brendel; S Schuman
Rat liver slices and diazepam metabolism: in vitro interactions with volatile anaesthetic drugs and albumin.
British journal of anaesthesia 1988;60(6):692-6.
1988: L Gunawardhana; J Barr; A J Weir; Klaus Brendel; I Glenn Sipes
Liver slices: an in vitro system for determination of N-acetylation in human liver.
Proceedings of the Western Pharmacology Society 1988;31():137-41.
1988: M S Stefaniak; A Gandolfi; Klaus Brendel
Adult rat lung in dynamic organ culture: a new tool in pharmacology.
Proceedings of the Western Pharmacology Society 1988;31():149-51.
1988: M S Connors; A Gandolfi; C L Krumdieck; Klaus Brendel
Lysosomal and cytosolic enzyme release as a measure of organelle specific toxicity in cultured rat liver slices.
Proceedings of the Western Pharmacology Society 1988;31():143-7.
1988: Z W Li; Klaus Brendel; A J Culling-Berglund; Thomas P Davis
Regional specificity of beta-endorphin metabolism in brain slices of the rat.
Proceedings of the Western Pharmacology Society 1988;31():67-70.
1988: CD Eskelson; V Stiffel; J A Owen; M Chvapil; A Vickers; Klaus Brendel
Changes in the fatty acid profile of lung, liver and serum of rats intratracheally given silica.
Life sciences 1988;42(15):1455-67.
1987: J S Phelps; A Gandolfi; Klaus Brendel; R T Dorr
Cisplatin nephrotoxicity: in vitro studies with precision-cut rabbit renal cortical slices.
Toxicology and applied pharmacology 1987;90(3):501-12.
1987: Klaus Brendel; R L McKee; Victor J Hruby; D G Johnson; A Gandolfi; C L Krumdieck
Precision cut tissue slices in culture: a new tool in pharmacology.
Proceedings of the Western Pharmacology Society 1987;30():291-3.
1986: P F Smith; G Krack; R L McKee; D G Johnson; A Gandolfi; Victor J Hruby; C L Krumdieck; Klaus Brendel
Maintenance of adult rat liver slices in dynamic organ culture.
In vitro cellular & developmental biology : journal of the Tissue Culture Association 1986;22(12):706-12.
1985: P F Smith; A Gandolfi; C L Krumdieck; C W Putnam; C F Zukoski; W M Davis; Klaus Brendel
Dynamic organ culture of precision liver slices for in vitro toxicology.
Life sciences 1985;36(14):1367-75.