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Rüdiger Woscholski

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Lok Hang Mak; David J Mann; Claire Scott; Katherine A Scott; James T Stivers; Gillian F Whyte; Oscar Ces; Jessica Knott; Yu Ye; Rüdiger Woscholski
Arylstibonic acids are potent and isoform-selective inhibitors of Cdc25a and Cdc25b phosphatases.
Alexandra Wormit; Rüdiger Woscholski; M C Laura Barter; Salman M Butt; Issariya Chairam; Alisdair R Fernie; Lars Kjaer; Joseph F McKenna; Adriano Nunes-Nesi; Kerry O'Donnelly; Thorsten Hamann
Osmosensitive changes of carbohydrate metabolism in response to cellulose biosynthesis inhibition.
Kalypso Charalambous; Robert V Law; John M Seddon; Richard H Templer; Rüdiger Woscholski; Laura M C Barter; Paula J Booth; Oscar Ces
Engineering de novo membrane-mediated protein-protein communication networks.

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2012: Lok Hang Mak; David J Mann; Claire Scott; Katherine A Scott; James T Stivers; Gillian F Whyte; Oscar Ces; Jessica Knott; Yu Ye; Rüdiger Woscholski
Arylstibonic acids are potent and isoform-selective inhibitors of Cdc25a and Cdc25b phosphatases.
Bioorganic & medicinal chemistry 2012;20(14):4371-6.
2012: Alexandra Wormit; Rüdiger Woscholski; M C Laura Barter; Salman M Butt; Issariya Chairam; Alisdair R Fernie; Lars Kjaer; Joseph F McKenna; Adriano Nunes-Nesi; Kerry O'Donnelly; Thorsten Hamann
Osmosensitive changes of carbohydrate metabolism in response to cellulose biosynthesis inhibition.
Plant physiology 2012;159(1):105-17.
2012: Kalypso Charalambous; Robert V Law; John M Seddon; Richard H Templer; Rüdiger Woscholski; Laura M C Barter; Paula J Booth; Oscar Ces
Engineering de novo membrane-mediated protein-protein communication networks.
Journal of the American Chemical Society 2012;134(13):5746-9.
2012: Marie-Charlotte Domart; Tina M C Hobday; Nirmal Jethwa; Christopher J Peddie; Dominic L Poccia; Michael J O Wakelam; Alan Wang; Rüdiger Woscholski; Karen Yeh; Qifeng Zhang; Richard D Byrne; Gary H C Chung; Lucy M Collinson; Banafshé Larijani
Acute manipulation of diacylglycerol reveals roles in nuclear envelope assembly & endoplasmic reticulum morphology.
PloS one 2012;7(12):e51150.
2010: Mark E B Smith; Richard M Gunn; Erika Rosivatz; Lok H Mak; Rüdiger Woscholski; Helen C Hailes
Development of chemical probes: toward the mode of action of a methylene-linked di(aryl acetate) E1.
Bioorganic & medicinal chemistry 2010;18(14):4917-27.
2009: Ka-Kei Ho; Evelyn Rosivatz; Richard M Gunn; Mark E B Smith; Alexandra V Stavropoulou; Erika Rosivatz; Macba G Numbere; John B Wong; Valerie G H Lafitte; Jonathan M Behrendt; Stephen S Myatt; Helen C Hailes; Rüdiger Woscholski; Eric W-F Lam
The novel molecule 2-[5-(2-chloroethyl)-2-acetoxy-benzyl]-4-(2-chloroethyl)-phenyl acetate inhibits phosphoinositide 3-kinase/Akt/mammalian target of rapamycin signalling through JNK activation in cancer cells.
The FEBS journal 2009;276(15):4037-50.
2009: Erika Rosivatz; Rüdiger Woscholski
Measurement of PTEN activity in vivo by imaging phosphorylated Akt.
Methods in molecular biology (Clifton, N.J.) 2009;462():213-22.
2009: Xavier Mulet; Erika Rosivatz; Ka-Kei Ho; Béatrice L L E Gauthé; Oscar Ces; Richard H Templer; Rüdiger Woscholski
Spatial localization of PtdInsP2 in phase-separated giant unilamellar vesicles with a fluorescent PLC-delta 1 PH domain.
Methods in molecular biology (Clifton, N.J.) 2009;462():135-44.
2008: Ka-Kei Ho; Alexandra A Anderson; Erika Rosivatz; Eric W-F Lam; Rüdiger Woscholski; David J Mann
Identification of cyclin A2 as the downstream effector of the nuclear phosphatidylinositol 4,5-bisphosphate signaling network.
The Journal of biological chemistry 2008;283(9):5477-85.
2007: Richard D Byrne; Erika Rosivatz; Maddy Parsons; Banafshé Larijani; Peter J Parker; Tony Ng; Rüdiger Woscholski
Differential activation of the PI 3-kinase effectors AKT/PKB and p70 S6 kinase by compound 48/80 is mediated by PKCalpha.
Cellular signalling 2007;19(2):321-9.
2006: Erika Rosivatz; Jonathan G Matthews; Neil McDonald; Xavier Mulet; Ka-Kei Ho; Nadine Lossi; Annette C Schmid; Marianna Mirabelli; Karen M Pomeranz; Christophe Erneux; Eric W-F Lam; Ramón Vilar; Rüdiger Woscholski
A small molecule inhibitor for phosphatase and tensin homologue deleted on chromosome 10 (PTEN).
ACS chemical biology 2006;1(12):780-90.
2006: Laura M C Barter; David R Klug; Rüdiger Woscholski
Does history repeat itself? The emergence of a new discipline.
ACS chemical biology 2006;1(12):737-40.
2006: N Fili; Véronique Calleja; Rüdiger Woscholski; Peter J Parker; Banafshé Larijani
Compartmental signal modulation: Endosomal phosphatidylinositol 3-phosphate controls endosome morphology and selective cargo sorting.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(42):15473-8.
2004: Annette C Schmid; Helen M Wise; Christina A Mitchell; Robert Nussbaum; Rüdiger Woscholski
Type II phosphoinositide 5-phosphatases have unique sensitivities towards fatty acid composition and head group phosphorylation.
FEBS letters 2004;576(1-2):9-13.
2004: Annette C Schmid; Richard D Byrne; Ramón Vilar; Rüdiger Woscholski
Bisperoxovanadium compounds are potent PTEN inhibitors.
FEBS letters 2004;566(1-3):35-8.
2004: Annette C Schmid; Rüdiger Woscholski
Phosphatases as small-molecule targets: inhibiting the endogenous inhibitors of kinases.
Biochemical Society transactions 2004;32(Pt 2):348-9.
2003: Martin Burke; Rüdiger Woscholski; Sophia N Yaliraki
Differential hydrophobicity drives self-assembly in Huntington's disease.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(24):13928-33.
2003: Véronique Calleja; Simon M Ameer-Beg; Borivoj Vojnovic; Rüdiger Woscholski; Julian Downward; Banafshé Larijani
Monitoring conformational changes of proteins in cells by fluorescence lifetime imaging microscopy.
The Biochemical journal 2003;372(Pt 1):33-40.
2002: Rüdiger Woscholski
Characterization and purification of phosphatidylinositol trisphosphate 5-phosphatase from rat brain tissues.
Methods in enzymology 2002;345():335-45.
2000: Sylvie Giuriato; Stephane Bodin; Christophe Erneux; Rüdiger Woscholski; Monique Plantavid; Hugues Chap; Bernard Payrastre
pp60c-src associates with the SH2-containing inositol-5-phosphatase SHIP1 and is involved in its tyrosine phosphorylation downstream of alphaIIbbeta3 integrin in human platelets.
The Biochemical journal 2000;348 Pt 1():107-12.
2000: WE Hughes; Rüdiger Woscholski; Frank T Cooke; R S Patrick; Stephen K Dove; Neil McDonald; Peter J Parker
SAC1 encodes a regulated lipid phosphoinositide phosphatase, defects in which can be suppressed by the homologous Inp52p and Inp53p phosphatases.
The Journal of biological chemistry 2000;275(2):801-8.
1998: Xavier Pesesse; Colette Moreau; A L Drayer; Rüdiger Woscholski; P Parker; Christophe Erneux
The SH2 domain containing inositol 5-phosphatase SHIP2 displays phosphatidylinositol 3,4,5-trisphosphate and inositol 1,3,4,5-tetrakisphosphate 5-phosphatase activity.
FEBS letters 1998;437(3):301-3.
1997: Sylvie Giuriato; Bernard Payrastre; A L Drayer; Monique Plantavid; Rüdiger Woscholski; P Parker; Christophe Erneux; Hugues Chap
Tyrosine phosphorylation and relocation of SHIP are integrin-mediated in thrombin-stimulated human blood platelets.
The Journal of biological chemistry 1997;272(43):26857-63.
1996: A L Drayer; Xavier Pesesse; Florence De Smedt; Rüdiger Woscholski; P Parker; Christophe Erneux
Cloning and expression of a human placenta inositol 1,3,4,5-tetrakisphosphate and phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase.
Biochemical and biophysical research communications 1996;225(1):243-9.