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Dorine Wouters

Research Profile

Chemicals & Drugs

Disorders

Anatomy

Procedures

Enzyme-Linked Immunosorbent Assay

Physiology

Transfection

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Publications

TOP 3
Pauline A van Schouwenburg; Gertjan Wolbink; Lucien Aarden; Els de Groot; Rob N de Jong; Margreet Hart; Simone Kruithof; Theo Rispens; Esther E L van Buren; Lotte A van de Stadt; S Marieke Van Ham; Dorine Wouters
Adalimumab elicits a restricted anti-idiotypic antibody response in autoimmune patients resulting in functional neutralisation.
Nicolaas A Verwey; Nicolaas Verwey; Harry A M Twaalfhoven; Dorine Wouters; Jeroen J M Hoozemans; Yves J M Bollen; Joep Killestein; Mirko Bibl; Jens Wiltfang; C Erik Hack; Philip scheltens; Marinus A Blankenstein
Quantification of amyloid-beta 40 in cerebrospinal fluid.
Elisa Giovannetti; Harold H J Backus; Dorine Wouters; Godefridus J Peters
Functional inactivity and mutations of p53 differentially affect sensitivity to 5-fluorouracil and antifolate inhibitors of thymidylate synthase (TS) by altering TS levels in colorectal cancer cells.

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All Publications

2013: Pauline A van Schouwenburg; Gertjan Wolbink; Lucien Aarden; Els de Groot; Rob N de Jong; Margreet Hart; Simone Kruithof; Theo Rispens; Esther E L van Buren; Lotte A van de Stadt; S Marieke Van Ham; Dorine Wouters
Adalimumab elicits a restricted anti-idiotypic antibody response in autoimmune patients resulting in functional neutralisation.
Annals of the rheumatic diseases 2013;72(1):104-9.
2009: Nicolaas A Verwey; Nicolaas Verwey; Harry A M Twaalfhoven; Dorine Wouters; Jeroen J M Hoozemans; Yves J M Bollen; Joep Killestein; Mirko Bibl; Jens Wiltfang; C Erik Hack; Philip scheltens; Marinus A Blankenstein
Quantification of amyloid-beta 40 in cerebrospinal fluid.
Journal of immunological methods 2009;348(1-2):57-66.
2008: Elisa Giovannetti; Harold H J Backus; Dorine Wouters; Godefridus J Peters
Functional inactivity and mutations of p53 differentially affect sensitivity to 5-fluorouracil and antifolate inhibitors of thymidylate synthase (TS) by altering TS levels in colorectal cancer cells.
Nucleosides, nucleotides & nucleic acids 2008;27(6):740-5.
2007: Merel C M Strik; Pieter J A de Koning; Monique J Kleijmeer; Bellinda A Bladergroen; Angela M Wolbink; Janice M Griffith; Dorine Wouters; Yoshihiro Fukuoka; Lawrence B Schwartz; C Erik Hack; S Marieke Van Ham; J Alain Kummer
Human mast cells produce and release the cytotoxic lymphocyte associated protease granzyme B upon activation.
Molecular immunology 2007;44(14):3462-72.
2007: Elisa Giovannetti; Harold H J Backus; Dorine Wouters; Carlos G Ferreira; Viola M M van Houten; Ruud H Brakenhoff; M-F Poupon; A Azzarello; HERBERT PINEDO; Godefridus J Peters
Changes in the status of p53 affect drug sensitivity to thymidylate synthase (TS) inhibitors by altering TS levels.
British journal of cancer 2007;96(5):769-75.
2005: Bellinda A Bladergroen; Merel C M Strik; Angela M Wolbink; Dorine Wouters; Roel Broekhuizen; J Alain Kummer; C Erik Hack
The granzyme B inhibitor proteinase inhibitor 9 (PI9) is expressed by human mast cells.
European journal of immunology 2005;35(4):1175-83.
2004: Merel C M Strik; Angela M Wolbink; Dorine Wouters; Bellinda A Bladergroen; Angelique R Verlaan; Inge Saskia van Houdt; Sanne Hijlkema; C Erik Hack; J Alain Kummer
Intracellular serpin SERPINB6 (PI6) is abundantly expressed by human mast cells and forms complexes with beta-tryptase monomers.
Blood 2004;103(7):2710-7.
2003: Jennifer Sigmond; Harold H J Backus; Dorine Wouters; Olaf H Temmink; Gerrit Jansen; Godefridus J Peters
Induction of resistance to the multitargeted antifolate Pemetrexed (ALIMTA) in WiDr human colon cancer cells is associated with thymidylate synthase overexpression.
Biochemical pharmacology 2003;66(3):431-8.
2003: Harold H J Backus; Dorine Wouters; Carlos G Ferreira; Viola M M van Houten; Ruud H Brakenhoff; HERBERT PINEDO; Godefridus J Peters
Thymidylate synthase inhibition triggers apoptosis via caspases-8 and -9 in both wild-type and mutant p53 colon cancer cell lines.
European journal of cancer (Oxford, England : 1990) 2003;39(9):1310-7.
2002: Merel C M Strik; Bellinda A Bladergroen; Dorine Wouters; Walter Kisiel; Jan Hendrik Hooijberg; Angelique R Verlaan; Peter L Hordijk; Pascal Schneider; C Erik Hack; J Alain Kummer
Distribution of the human intracellular serpin protease inhibitor 8 in human tissues.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2002;50(11):1443-54.
2002: Harold H J Backus; Cees J van Groeningen; Wim Vos; Danny F Dukers; Elisabeth Bloemena; Dorine Wouters; HERBERT PINEDO; Godefridus J Peters
Differential expression of cell cycle and apoptosis related proteins in colorectal mucosa, primary colon tumours, and liver metastases.
Journal of clinical pathology 2002;55(3):206-11.
2001: Annette van der Goes; Dorine Wouters; Susanne M A van der Pol; R Huizinga; Eric Ronken; P Adamson; John Greenwood; Christine D Dijkstra; Helga E de Vries
Reactive oxygen species enhance the migration of monocytes across the blood-brain barrier in vitro.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(10):1852-4.
2001: Bart A Westerman; Ankie Poutsma; Leendert H J Looijenga; Dorine Wouters; Inge J van Wijk; Cees B M Oudejans
The Human Achaete Scute Homolog 2 gene contains two promotors, generating overlapping transcripts and encoding two proteins with different nuclear localization.
Placenta 2001;22(6):511-8.
2001: Harold H J Backus; J M G H van Riel; Cees J van Groeningen; Wim Vos; Danny F Dukers; Elisabeth Bloemena; Dorine Wouters; HERBERT PINEDO; Godefridus J Peters
Rb, mcl-1 and p53 expression correlate with clinical outcome in patients with liver metastases from colorectal cancer.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2001;12(6):779-85.
2001: Cees B M Oudejans; Bart A Westerman; Dorine Wouters; S Gooyer; P A J Leegwater; Inge J van Wijk; F Sleutels
Allelic IGF2R repression does not correlate with expression of antisense RNA in human extraembryonic tissues.
Genomics 2001;73(3):331-7.
2001: Clasina L Van der Wilt; Harold H J Backus; Kees Smid; L Comijn; Gijsbert Veerman; Dorine Wouters; Daphne Voorn; David G Priest; Marlene A Bunni; Fraser Mitchell; Ann L Jackman; Gerrit Jansen; Godefridus J Peters
Modulation of both endogenous folates and thymidine enhance the therapeutic efficacy of thymidylate synthase inhibitors.
Cancer research 2001;61(9):3675-81.
2001: Harold H J Backus; Danny F Dukers; Cees J van Groeningen; Wim Vos; Elisabeth Bloemena; Dorine Wouters; J M G H van Riel; Kees Smid; Giuseppe Giaccone; HERBERT PINEDO; Godefridus J Peters
5-Fluorouracil induced Fas upregulation associated with apoptosis in liver metastases of colorectal cancer patients.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2001;12(2):209-16.
2000: Harold H J Backus; HERBERT PINEDO; Dorine Wouters; Jose Padron; N Molders; Clasina L Van der Wilt; Cees J van Groeningen; Gerrit Jansen; Godefridus J Peters
Folate depletion increases sensitivity of solid tumor cell lines to 5-fluorouracil and antifolates.
International journal of cancer. Journal international du cancer 2000;87(6):771-8.
2000: Harold H J Backus; Dorine Wouters; Clasina L Van der Wilt; CM Kuiper; Cees J van Groeningen; HERBERT PINEDO; Godefridus J Peters
Thymidylate synthase inhibition induces p53 dependent and independent cell death.
Advances in experimental medicine and biology 2000;486():303-6.
2000: Harold H J Backus; HERBERT PINEDO; Dorine Wouters; CM Kuiper; Gerrit Jansen; Cees J van Groeningen; Godefridus J Peters
Differences in the induction of DNA damage, cell cycle arrest, and cell death by 5-fluorouracil and antifolates.
Oncology research 2000;12(5):231-9.