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Eugene Wright

Research Profile

Chemicals & Drugs

Anatomy

Microsomes, Liver

Physiology

Procedures

Concepts & Ideas

Area Under Curve

Phenomena

Metabolic Clearance Rate

Co-author Network

Publications

TOP 3
David J Greenblatt; Jerold S Harmatz; Lisa L Von Moltke; C Eugene Wright; Richard I Shader
Age and gender effects on the pharmacokinetics and pharmacodynamics of triazolam, a cytochrome P450 3A substrate.
David J Greenblatt; Jerold S Harmatz; Lisa L Von Moltke; C Eugene Wright; AL Durol; L M Harrel-Joseph; Richard I Shader
Comparative kinetics and response to the benzodiazepine agonists triazolam and zolpidem: evaluation of sex-dependent differences.
David J Greenblatt; Lisa L Von Moltke; Jerold S Harmatz; M Counihan; Jennifer A Graf; AL Durol; Polyxane Mertzanis; Su X Duan; C Eugene Wright; Richard I Shader
Inhibition of triazolam clearance by macrolide antimicrobial agents: in vitro correlates and dynamic consequences.

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All Publications

2004: David J Greenblatt; Jerold S Harmatz; Lisa L Von Moltke; C Eugene Wright; Richard I Shader
Age and gender effects on the pharmacokinetics and pharmacodynamics of triazolam, a cytochrome P450 3A substrate.
Clinical pharmacology and therapeutics 2004;76(5):467-79.
2000: David J Greenblatt; Jerold S Harmatz; Lisa L Von Moltke; C Eugene Wright; AL Durol; L M Harrel-Joseph; Richard I Shader
Comparative kinetics and response to the benzodiazepine agonists triazolam and zolpidem: evaluation of sex-dependent differences.
The Journal of pharmacology and experimental therapeutics 2000;293(2):435-43.
1998: David J Greenblatt; Lisa L Von Moltke; Jerold S Harmatz; M Counihan; Jennifer A Graf; AL Durol; Polyxane Mertzanis; Su X Duan; C Eugene Wright; Richard I Shader
Inhibition of triazolam clearance by macrolide antimicrobial agents: in vitro correlates and dynamic consequences.
Clinical pharmacology and therapeutics 1998;64(3):278-85.
1998: David J Greenblatt; C Eugene Wright; Lisa L Von Moltke; Jerold S Harmatz; Bruce L Ehrenberg; L M Harrel; Kathleen E Corbett; M Counihan; S Tobias; Richard I Shader
Ketoconazole inhibition of triazolam and alprazolam clearance: differential kinetic and dynamic consequences.
Clinical pharmacology and therapeutics 1998;64(3):237-47.
1998: Lisa L Von Moltke; David J Greenblatt; J Schmider; C Eugene Wright; Jerold S Harmatz; Richard I Shader
In vitro approaches to predicting drug interactions in vivo.
Biochemical pharmacology 1998;55(2):113-22.
1997: Lisa L Von Moltke; David J Greenblatt; Su X Duan; J Schmider; C Eugene Wright; Jerold S Harmatz; Richard I Shader
Human cytochromes mediating N-demethylation of fluoxetine in vitro.
Psychopharmacology 1997;132(4):402-7.
1996: Lisa L Von Moltke; David J Greenblatt; J Schmider; Su X Duan; C Eugene Wright; Jerold S Harmatz; Richard I Shader
Midazolam hydroxylation by human liver microsomes in vitro: inhibition by fluoxetine, norfluoxetine, and by azole antifungal agents.
Journal of clinical pharmacology 1996;36(9):783-91.
1996: Lisa L Von Moltke; David J Greenblatt; Su X Duan; Jerold S Harmatz; C Eugene Wright; Richard I Shader
Inhibition of terfenadine metabolism in vitro by azole antifungal agents and by selective serotonin reuptake inhibitor antidepressants: relation to pharmacokinetic interactions in vivo.
Journal of clinical psychopharmacology 1996;16(2):104-12.
1996: Lisa L Von Moltke; David J Greenblatt; Jerold S Harmatz; Su X Duan; L M Harrel; M M Cotreau-Bibbo; Gary A Pritchard; C Eugene Wright; Richard I Shader
Triazolam biotransformation by human liver microsomes in vitro: effects of metabolic inhibitors and clinical confirmation of a predicted interaction with ketoconazole.
The Journal of pharmacology and experimental therapeutics 1996;276(2):370-9.
1995: David J Greenblatt; Lisa L Von Moltke; Jerold S Harmatz; L M Harrel; S Tobias; Richard I Shader; C Eugene Wright
Interaction of triazolam and ketoconazole.
Lancet 1995;345(8943):191.
1993: David J Greenblatt; C Eugene Wright
Clinical pharmacokinetics of alprazolam. Therapeutic implications.
Clinical pharmacokinetics 1993;24(6):453-71.