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Patrick Brennan

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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TOP 3
Mascitti Kara B; Manaker Scott; Rohrbach Jeff; Brennan Patrick J; Fishman Neil O
Limitations in using aspiration pneumonia as a quality measure.
Scherman Hataichanok; Kaur Devinder; Pham Ha; Skovierová Henrieta; Jackson Mary; Brennan Patrick J
Identification of a polyprenylphosphomannosyl synthase involved in the synthesis of mycobacterial mannosides.
Skovierová Henrieta; Larrouy-Maumus Gérald; Zhang Jian; Kaur Devinder; Barilone Nathalie; Korduláková Jana; Gilleron Martine; Guadagnini Stéphanie; Belanová Martina; Prevost Marie-Christine; Gicquel Brigitte; Puzo Germain; Chatterjee Delphi; Brennan Patrick J; Nigou Jérôme; Jackson Mary
AftD, a novel essential arabinofuranosyltransferase from mycobacteria.

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All Publications

2009: Mascitti Kara B; Manaker Scott; Rohrbach Jeff; Brennan Patrick J; Fishman Neil O
Limitations in using aspiration pneumonia as a quality measure.
Infection control and hospital epidemiology : the official journal of the Society of Hospital Epidemiologists of America 2009;30(12):1233-5.
2009: Scherman Hataichanok; Kaur Devinder; Pham Ha; Skovierová Henrieta; Jackson Mary; Brennan Patrick J
Identification of a polyprenylphosphomannosyl synthase involved in the synthesis of mycobacterial mannosides.
Journal of bacteriology 2009;191(21):6769-72.
2009: Skovierová Henrieta; Larrouy-Maumus Gérald; Zhang Jian; Kaur Devinder; Barilone Nathalie; Korduláková Jana; Gilleron Martine; Guadagnini Stéphanie; Belanová Martina; Prevost Marie-Christine; Gicquel Brigitte; Puzo Germain; Chatterjee Delphi; Brennan Patrick J; Nigou Jérôme; Jackson Mary
AftD, a novel essential arabinofuranosyltransferase from mycobacteria.
Glycobiology 2009;19(11):1235-47.
2009: Guerin Marcelo E; Kaur Devinder; Somashekar B S; Gibbs Sara; Gest Petra; Chatterjee Delphi; Brennan Patrick J; Jackson Mary
New insights into the early steps of phosphatidylinositol mannoside biosynthesis in mycobacteria: PimB' is an essential enzyme of Mycobacterium smegmatis.
The Journal of biological chemistry 2009;284(38):25687-96.
2009: Sakamuri Rama Murthy; Kimura Miyako; Li Wei; Kim Hyun-Chul; Lee Hyeyoung; Kiran Madanahally D; Black William C; Balagon Marivic; Gelber Robert; Cho Sang-Nae; Brennan Patrick J; Vissa Varalakshmi
Population-based molecular epidemiology of leprosy in Cebu, Philippines.
Journal of clinical microbiology 2009;47(9):2844-54.
2009: Gasink Leanne B; Brennan Patrick J
Isolation precautions for antibiotic-resistant bacteria in healthcare settings.
Current opinion in infectious diseases 2009;22(4):339-44.
2009: Kimura Miyako; Sakamuri Rama Murthy; Groathouse Nathan A; Rivoire Becky L; Gingrich David; Krueger-Koplin Susan; Cho Sang-Nae; Brennan Patrick J; Vissa Varalakshmi
Rapid variable-number tandem-repeat genotyping for Mycobacterium leprae clinical specimens.
Journal of clinical microbiology 2009;47(6):1757-66.
2009: de Lima Cristiana Soares; Marques Maria A M; Debrie Anne-Sophie; Almeida Elza C C; Silva Carlos A M; Brennan Patrick J; Sarno Euzenir N; Menozzi Franco D; Pessolani Maria C V
Heparin-binding hemagglutinin (HBHA) of Mycobacterium leprae is expressed during infection and enhances bacterial adherence to epithelial cells.
FEMS microbiology letters 2009;292(2):162-9.
2009: Geluk Annemieke; Spencer John S; Bobosha Kidist; Pessolani Maria C V; Pereira Geraldo M B; Banu Sayera; Honoré Nadine; Reece Stephen T; MacDonald Murdo; Sapkota Bishwa Raj; Ranjit Chaman; Franken Kees L M C; Zewdie Martha; Aseffa Abraham; Hussain Rabia; Stefani Mariane M; Cho Sang-Nae; Oskam Linda; Brennan Patrick J; Dockrell Hazel M;
From genome-based in silico predictions to ex vivo verification of leprosy diagnosis.
Clinical and vaccine immunology : CVI 2009;16(3):352-9.
2009: Eoh Hyungjin; Brennan Patrick J; Crick Dean C
The Mycobacterium tuberculosis MEP (2C-methyl-d-erythritol 4-phosphate) pathway as a new drug target.
Tuberculosis (Edinburgh, Scotland) 2009;89(1):1-11.
2009: Jackson Mary; Brennan Patrick J
Polymethylated polysaccharides from Mycobacterium species revisited.
The Journal of biological chemistry 2009;284(4):1949-53.
2009: Kaur Devinder; Pham Ha; Larrouy-Maumus Gérald; Rivière Michel; Vissa Varalakshmi; Guerin Marcelo E; Puzo Germain; Brennan Patrick J; Jackson Mary
Initiation of methylglucose lipopolysaccharide biosynthesis in mycobacteria.
PloS one 2009;4(5):e5447.
2008: Gest Petra; Kaur Devinder; Pham Ha T; van der Woerd Mark; Hansen Emily; Brennan Patrick J; Jackson Mary; Guerin Marcelo E
Preliminary crystallographic analysis of GpgS, a key glucosyltransferase involved in methylglucose lipopolysaccharide biosynthesis in Mycobacterium tuberculosis.
Acta crystallographica. Section F, Structural biology and crystallization communications 2008;64(Pt 12):1121-4.
2008: Kaur Devinder; Obregón-Henao Andrés; Pham Ha; Chatterjee Delphi; Brennan Patrick J; Jackson Mary
Lipoarabinomannan of Mycobacterium: mannose capping by a multifunctional terminal mannosyltransferase.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(46):17973-7.
2008: Martinez Lorene R; Harris Beth; Black William C; Meyer Robert M; Brennan Patrick J; Vissa Varalakshmi D; Jones Robert L
Genotyping North American animal Mycobacterium bovis isolates using multilocus variable number tandem repeat analysis.
Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc 2008;20(6):707-15.
2008: Torrelles Jordi B; Knaup Rose; Kolareth Avina; Slepushkina Tatiana; Kaufman Thomas M; Kang Peter; Hill Preston J; Brennan Patrick J; Chatterjee Delphi; Belisle John T; Musser James M; Schlesinger Larry S
Identification of Mycobacterium tuberculosis clinical isolates with altered phagocytosis by human macrophages due to a truncated lipoarabinomannan.
The Journal of biological chemistry 2008;283(46):31417-28.
2008: Rudeeaneksin Janisara; Srisungngam Sopa; Sawanpanyalert Pathom; Sittiwakin Thaverit; Likanonsakul Sirirat; Pasadorn Supannee; Palittapongarnpim Prasit; Brennan Patrick J; Phetsuksiri Benjawan
LightCycler real-time PCR for rapid detection and quantitation of Mycobacterium leprae in skin specimens.
FEMS immunology and medical microbiology 2008;54(2):263-70.
2008: Monot Marc; Honoré Nadine; Balière Charlotte; Ji Baohong; Sow Samba; Brennan Patrick J; Cole Stewart T
Are variable-number tandem repeats appropriate for genotyping Mycobacterium leprae?
Journal of clinical microbiology 2008;46(7):2291-7.
2008: Marques Maria Angela M; Neves-Ferreira Ana Gisele C; da Silveira Erika K Xavier; Valente Richard H; Chapeaurouge Alexander; Perales Jonas; da Silva Bernardes Renato; Dobos Karen M; Spencer John S; Brennan Patrick J; Pessolani Maria Cristina V
Deciphering the proteomic profile of Mycobacterium leprae cell envelope.
Proteomics 2008;8(12):2477-91.
2008: Liav Avraham; Angala Shiva K; Brennan Patrick J; Jackson Mary
N-D-aldopentofuranosyl-N'-[p-(isoamyloxy)phenyl]-thiourea derivatives: potential anti-TB therapeutic agents.
Bioorganic & medicinal chemistry letters 2008;18(8):2649-51.
2008: Belánová Martina; Dianisková Petronela; Brennan Patrick J; Completo Gladys C; Rose Natisha L; Lowary Todd L; Mikusová Katarína
Galactosyl transferases in mycobacterial cell wall synthesis.
Journal of bacteriology 2008;190(3):1141-5.
2008: Mahapatra Sebabrata; Crick Dean C; McNeil Michael R; Brennan Patrick J
Unique structural features of the peptidoglycan of Mycobacterium leprae.
Journal of bacteriology 2008;190(2):655-61.
2007: Eoh Hyungjin; Brown Amanda C; Buetow Lori; Hunter William N; Parish Tanya; Kaur Devinder; Brennan Patrick J; Crick Dean C
Characterization of the Mycobacterium tuberculosis 4-diphosphocytidyl-2-C-methyl-D-erythritol synthase: potential for drug development.
Journal of bacteriology 2007;189(24):8922-7.
2007: Wasserstein Alan G; Brennan Patrick J; Rubenstein Arthur H
Institutional leadership and faculty response: fostering professionalism at the University of Pennsylvania School of Medicine.
Academic medicine : journal of the Association of American Medical Colleges 2007;82(11):1049-56.
2007: Korduláková Jana; Janin Yves L; Liav Avraham; Barilone Nathalie; Dos Vultos Tiago; Rauzier Jean; Brennan Patrick J; Gicquel Brigitte; Jackson Mary
Isoxyl activation is required for bacteriostatic activity against Mycobacterium tuberculosis.
Antimicrobial agents and chemotherapy 2007;51(11):3824-9.
2007: Kincaid Eleanor Z; Wolf Andrea J; Desvignes Ludovic; Mahapatra Sebabrata; Crick Dean C; Brennan Patrick J; Pavelka Martin S; Ernst Joel D
Codominance of TLR2-dependent and TLR2-independent modulation of MHC class II in Mycobacterium tuberculosis infection in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(5):3187-95.
2007: Kaur Devinder; McNeil Michael R; Khoo Kay-Hooi; Chatterjee Delphi; Crick Dean C; Jackson Mary; Brennan Patrick J
New insights into the biosynthesis of mycobacterial lipomannan arising from deletion of a conserved gene.
The Journal of biological chemistry 2007;282(37):27133-40.
2007: Weng Xiaoman; Wang Zheng; Liu Jian; Kimura Miyako; Black William C; Brennan Patrick J; Li Huanying; Vissa Varalakshmi D
Identification and distribution of Mycobacterium leprae genotypes in a region of high leprosy prevalence in China: a 3-year molecular epidemiological study.
Journal of clinical microbiology 2007;45(6):1728-34.
2007: Berg Stefan; Kaur Devinder; Jackson Mary; Brennan Patrick J
The glycosyltransferases of Mycobacterium tuberculosis - roles in the synthesis of arabinogalactan, lipoarabinomannan, and other glycoconjugates.
Glycobiology 2007;17(6):35-56R.
2007: Martins Marcia Valéria B S; Lima Mônica Cristina B S; Duppre Nadia C; Matos Haroldo J; Spencer John S; Brennan Patrick J; Sarno Euzenir N; Fonseca Leila; Pereira Geraldo M B; Pessolani Maria Cristina V
The level of PPD-specific IFN-gamma-producing CD4+ T cells in the blood predicts the in vivo response to PPD.
Tuberculosis (Edinburgh, Scotland) 2007;87(3):202-11.
2007: Biet Franck; Angela de Melo Marques Maria; Grayon Maggy; Xavier da Silveira Erika Kopp; Brennan Patrick J; Drobecq Hervé; Raze Dominique; Vidal Pessolani Maria Cristina; Locht Camille; Menozzi Franco Dante
Mycobacterium smegmatis produces an HBHA homologue which is not involved in epithelial adherence.
Microbes and infection / Institut Pasteur 2007;9(2):175-82.
2007: Brennan Patrick J; Crick Dean C
The cell-wall core of Mycobacterium tuberculosis in the context of drug discovery.
Current topics in medicinal chemistry 2007;7(5):475-88.
2006: Phetsuksiri Benjawan; Rudeeaneksin Janisara; Supapkul Prapaporn; Wachapong Suksawat; Mahotarn Krisada; Brennan Patrick J
A simplified reverse transcriptase PCR for rapid detection of Mycobacterium leprae in skin specimens.
FEMS immunology and medical microbiology 2006;48(3):319-28.
2006: Groathouse Nathan A; Amin Amol; Marques Maria Angela M; Spencer John S; Gelber Robert; Knudson Dennis L; Belisle John T; Brennan Patrick J; Slayden Richard A
Use of protein microarrays to define the humoral immune response in leprosy patients and identification of disease-state-specific antigenic profiles.
Infection and immunity 2006;74(11):6458-66.
2006: Mikusová Katarína; Belánová Martina; Korduláková Jana; Honda Kristine; McNeil Michael R; Mahapatra Sebabrata; Crick Dean C; Brennan Patrick J
Identification of a novel galactosyl transferase involved in biosynthesis of the mycobacterial cell wall.
Journal of bacteriology 2006;188(18):6592-8.
2006: Kaur Devinder; Berg Stefan; Dinadayala Premkumar; Gicquel Brigitte; Chatterjee Delphi; McNeil Michael R; Vissa Varalakshmi D; Crick Dean C; Jackson Mary; Brennan Patrick J
Biosynthesis of mycobacterial lipoarabinomannan: role of a branching mannosyltransferase.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(37):13664-9.
2006: Aráoz Romulo; Honoré Nadine; Banu Sayera; Demangel Caroline; Cissoko Yakouba; Arama Charles; Uddin Mohammad Khaja Mafij; Hadi S K Abdul; Monot Marc; Cho Sang-Nae; Ji Baohong; Brennan Patrick J; Sow Samba; Cole Stewart T
Towards an immunodiagnostic test for leprosy.
Microbes and infection / Institut Pasteur 2006;8(8):2270-6.
2006: Dinadayala Premkumar; Kaur Devinder; Berg Stefan; Amin Anita G; Vissa Varalakshmi D; Chatterjee Delphi; Brennan Patrick J; Crick Dean C
Genetic basis for the synthesis of the immunomodulatory mannose caps of lipoarabinomannan in Mycobacterium tuberculosis.
The Journal of biological chemistry 2006;281(29):20027-35.
2006: Brennan Patrick J; Saouaf Sandra J; Van Dyken Steve; Marth Jamey D; Li Bin; Bhandoola Avinash; Greene Mark I
Sialylation regulates peripheral tolerance in CD4+ T cells.
International immunology 2006;18(5):627-35.
2006: Groathouse Nathan A; Brown Susan E; Knudson Dennis L; Brennan Patrick J; Slayden Richard A
Isothermal amplification and molecular typing of the obligate intracellular pathogen Mycobacterium leprae isolated from tissues of unknown origins.
Journal of clinical microbiology 2006;44(4):1502-8.
2006: Aráoz Romulo; Honoré Nadine; Cho Sungae; Kim Jong-Pill; Cho Sang-Nae; Monot Marc; Demangel Caroline; Brennan Patrick J; Cole Stewart T
Antigen discovery: a postgenomic approach to leprosy diagnosis.
Infection and immunity 2006;74(1):175-82.
2005: Spencer John S; Dockrell Hazel M; Kim Hee Jin; Marques Maria A M; Williams Diana L; Martins Marcia V S B; Martins Marcio L F; Lima Monica C B S; Sarno Euzenir N; Pereira Geraldo M B; Matos Haroldo; Fonseca Leila S; Sampaio Elisabeth P; Ottenhoff Thomas H M; Geluk Annemieke; Cho Sang-Nae; Stoker Neil G; Cole Stewart T; Brennan Patrick J; Pessolani Maria C V
Identification of specific proteins and peptides in mycobacterium leprae suitable for the selective diagnosis of leprosy.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(12):7930-8.
2005: Mikusová Katarína; Huang Hairong; Yagi Tetsuya; Holsters Marcelle; Vereecke Danny; D'Haeze Wim; Scherman Michael S; Brennan Patrick J; McNeil Michael R; Crick Dean C
Decaprenylphosphoryl arabinofuranose, the donor of the D-arabinofuranosyl residues of mycobacterial arabinan, is formed via a two-step epimerization of decaprenylphosphoryl ribose.
Journal of bacteriology 2005;187(23):8020-5.
2005: Geluk Annemieke; Klein Michèl R; Franken Kees L M C; van Meijgaarden Krista E; Wieles Brigitte; Pereira Kelly Cristina; Bührer-Sékula Samira; Klatser Paul R; Brennan Patrick J; Spencer John S; Williams Diana L; Pessolani Maria C V; Sampaio Elizabeth P; Ottenhoff Tom H M
Postgenomic approach to identify novel Mycobacterium leprae antigens with potential to improve immunodiagnosis of infection.
Infection and immunity 2005;73(9):5636-44.
2005: Soares de Lima Cristiana; Zulianello Laurence; Marques Maria Angela de Melo; Kim Heejin; Portugal Michelle Iespa; Antunes Sérgio Luiz; Menozzi Franco Dante; Ottenhoff Tom Henricus Maria; Brennan Patrick Joseph; Pessolani Maria Cristina Vidal
Mapping the laminin-binding and adhesive domain of the cell surface-associated Hlp/LBP protein from Mycobacterium leprae.
Microbes and infection / Institut Pasteur 2005;7(9-10):1097-109.
2005: Monot Marc; Honoré Nadine; Garnier Thierry; Araoz Romulo; Coppée Jean-Yves; Lacroix Céline; Sow Samba; Spencer John S; Truman Richard W; Williams Diana L; Gelber Robert; Virmond Marcos; Flageul Béatrice; Cho Sang-Nae; Ji Baohong; Paniz-Mondolfi Alberto; Convit Jacinto; Young Saroj; Fine Paul E; Rasolofo Voahangy; Brennan Patrick J; Cole Stewart T
On the origin of leprosy.
Science (New York, N.Y.) 2005;308(5724):1040-2.
2005: Mahapatra Sebabrata; Yagi Tetsuya; Belisle John T; Espinosa Benjamin J; Hill Preston J; McNeil Michael R; Brennan Patrick J; Crick Dean C
Mycobacterial lipid II is composed of a complex mixture of modified muramyl and peptide moieties linked to decaprenyl phosphate.
Journal of bacteriology 2005;187(8):2747-57.
2005: Mahapatra Sebabrata; Scherman Hataichanok; Brennan Patrick J; Crick Dean C
N Glycolylation of the nucleotide precursors of peptidoglycan biosynthesis of Mycobacterium spp. is altered by drug treatment.
Journal of bacteriology 2005;187(7):2341-7.
2005: Sieling Peter A; Torrelles Jordi B; Stenger Steffen; Chung Woosin; Burdick Anne E; Rea Thomas H; Brennan Patrick J; Belisle John T; Porcelli Steven A; Modlin Robert L
The human CD1-restricted T cell repertoire is limited to cross-reactive antigens: implications for host responses against immunologically related pathogens.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(5):2637-44.
2005: Berg Stefan; Starbuck James; Torrelles Jordi B; Vissa Varalakshmi D; Crick Dean C; Chatterjee Delphi; Brennan Patrick J
Roles of conserved proline and glycosyltransferase motifs of EmbC in biosynthesis of lipoarabinomannan.
The Journal of biological chemistry 2005;280(7):5651-63.
2004: Kaur Devinder; Brennan Patrick J; Crick Dean C
Decaprenyl diphosphate synthesis in Mycobacterium tuberculosis.
Journal of bacteriology 2004;186(22):7564-70.
2004: Marques Maria Angela M; Espinosa Benjamin J; Xavier da Silveira Erika K; Pessolani Maria Cristina V; Chapeaurouge Alex; Perales Jonas; Dobos Karen M; Belisle John T; Spencer John S; Brennan Patrick J
Continued proteomic analysis of Mycobacterium leprae subcellular fractions.
Proteomics 2004;4(10):2942-53.
2004: Torrelles Jordi B; Khoo Kay-Hooi; Sieling Peter A; Modlin Robert L; Zhang Nannan; Marques Angela M; Treumann Achim; Rithner Christopher D; Brennan Patrick J; Chatterjee Delphi
Truncated structural variants of lipoarabinomannan in Mycobacterium leprae and an ethambutol-resistant strain of Mycobacterium tuberculosis.
The Journal of biological chemistry 2004;279(39):41227-39.
2004: Wengenack Nancy L; Lane Brian D; Hill Preston J; Uhl James R; Lukat-Rodgers Gudrun S; Hall Leslie; Roberts Glenn D; Cockerill Franklin R; Brennan Patrick J; Rodgers Kenton R; Belisle John T; Rusnak Frank
Purification and characterization of Mycobacterium tuberculosis KatG, KatG(S315T), and Mycobacterium bovis KatG(R463L).
Protein expression and purification 2004;36(2):232-43.
2004: Spencer John S; Kim Hee Jin; Marques Angela M; Gonzalez-Juarerro Mercedes; Lima Monica C B S; Vissa Varalakshmi D; Truman Richard W; Gennaro Maria Laura; Cho Sang-Nae; Cole Stewart T; Brennan Patrick J
Comparative analysis of B- and T-cell epitopes of Mycobacterium leprae and Mycobacterium tuberculosis culture filtrate protein 10.
Infection and immunity 2004;72(6):3161-70.
2004: Dhiman Rakesh K; Schulbach Mark C; Mahapatra Sebabrata; Baulard Alain R; Vissa Varalakshmi; Brennan Patrick J; Crick Dean C
Identification of a novel class of omega,E,E-farnesyl diphosphate synthase from Mycobacterium tuberculosis.
Journal of lipid research 2004;45(6):1140-7.
2004: Yamashita Yasuko; Maeda Yumi; Takeshita Fumihiko; Brennan Patrick J; Makino Masahiko
Role of the polypeptide region of a 33kDa mycobacterial lipoprotein for efficient IL-12 production.
Cellular immunology 2004;229(1):13-20.
2004: Groathouse Nathan A; Rivoire Becky; Kim Hansuk; Lee Hyeyoung; Cho Sang-Nae; Brennan Patrick J; Vissa Varalakshmi D
Multiple polymorphic loci for molecular typing of strains of Mycobacterium leprae.
Journal of clinical microbiology 2004;42(4):1666-72.
2004: Hunger Robert E; Sieling Peter A; Ochoa Maria Teresa; Sugaya Makoto; Burdick Anne E; Rea Thomas H; Brennan Patrick J; Belisle John T; Blauvelt Andrew; Porcelli Steven A; Modlin Robert L
Langerhans cells utilize CD1a and langerin to efficiently present nonpeptide antigens to T cells.
The Journal of clinical investigation 2004;113(5):701-8.
2004: Maeda Yumi; Brennan Patrick J; Makino Masahiko
Studies of lipoproteins of Mycobacterium leprae.
Nihon Hansenbyo Gakkai zasshi = Japanese journal of leprosy : official organ of the Japanese Leprosy Association 2004;73(1):15-21.
2004: Henning Kelly J; Brennan Patrick J; Hoegg Cindy; O'Rourke Eileen; Dyer Bernard D; Grace Thomas L
Health system preparedness for bioterrorism: bringing the tabletop to the hospital.
Infection control and hospital epidemiology : the official journal of the Society of Hospital Epidemiologists of America 2004;25(2):146-55.
2004: Coxon Geoffrey D; Al Dulayymi Juma'a R; Morehouse Caroline; Brennan Patrick J; Besra Gurdyal S; Baird Mark S; Minnikin David E
Synthesis and properties of methyl 5-(1'R,2'S)-(2-octadecylcycloprop-1-yl)pentanoate and other omega-19 chiral cyclopropane fatty acids and esters related to mycobacterial mycolic acids.
Chemistry and physics of lipids 2004;127(1):35-46.
2003: Phetsuksiri Benjawan; Jackson Mary; Scherman Hataichanok; McNeil Michael; Besra Gurdyal S; Baulard Alain R; Slayden Richard A; DeBarber Andrea E; Barry Clifton E; Baird Mark S; Crick Dean C; Brennan Patrick J
Unique mechanism of action of the thiourea drug isoxyl on Mycobacterium tuberculosis.
The Journal of biological chemistry 2003;278(52):53123-30.
2003: Zhang Nannan; Torrelles Jordi B; McNeil Michael R; Escuyer Vincent E; Khoo Kay-Hooi; Brennan Patrick J; Chatterjee Delphi
The Emb proteins of mycobacteria direct arabinosylation of lipoarabinomannan and arabinogalactan via an N-terminal recognition region and a C-terminal synthetic region.
Molecular microbiology 2003;50(1):69-76.
2003: Korduláková Jana; Gilleron Martine; Puzo Germain; Brennan Patrick J; Gicquel Brigitte; Mikusová Katarina; Jackson Mary
Identification of the required acyltransferase step in the biosynthesis of the phosphatidylinositol mannosides of mycobacterium species.
The Journal of biological chemistry 2003;278(38):36285-95.
2003: Chua-Intra Boosbun; Wattanapokayakit Sukanya; Srisungngam Sopa; Srisungngam Tawee; Mahotarn Krisada; Brennan Patrick J; Ivanyi Juraj
T-cell recognition of peptides from the Mycobacterium leprae 35 kDa protein in Thai leprosy patients, healthy contacts, and non-contacts.
Immunology letters 2003;88(1):71-6.
2003: Yagi Tetsuya; Mahapatra Sebabrata; Mikusova Katarina; Crick Dean C; Brennan Patrick J
Polymerization of mycobacterial arabinogalactan and ligation to peptidoglycan.
The Journal of biological chemistry 2003;278(29):26497-504.
2003: Krutzik Stephan R; Ochoa Maria Teresa; Sieling Peter A; Uematsu Satoshi; Ng Yolanda W; Legaspi Annaliza; Liu Philip T; Cole Stewart T; Godowski Paul J; Maeda Yumi; Sarno Euzenir N; Norgard Michael V; Brennan Patrick J; Akira Shizuo; Rea Thomas H; Modlin Robert L
Activation and regulation of Toll-like receptors 2 and 1 in human leprosy.
Nature medicine 2003;9(5):525-32.
2003: McGovern Paul C; Lautenbach Ebbing; Brennan Patrick J; Lustig Robert A; Fishman Neil O
Risk factors for postcraniotomy surgical site infection after 1,3-bis (2-chloroethyl)-1-nitrosourea (Gliadel) wafer placement.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2003;36(6):759-65.
2003: Saouaf Sandra J; Brennan Patrick J; Shen Yuan; Greene Mark I
Mechanisms of peripheral immune tolerance: conversion of the immune to the unresponsive phenotype.
Immunologic research 2003;28(3):193-9.
2003: Brennan Patrick J; Saouaf Sandra J; Greene Mark I; Shen Yuan
Anergy and suppression as coexistent mechanisms for the maintenance of peripheral T cell tolerance.
Immunologic research 2003;27(2-3):295-302.
2003: Brennan P J
Structure, function, and biogenesis of the cell wall of Mycobacterium tuberculosis.
Tuberculosis (Edinburgh, Scotland) 2003;83(1-3):91-7.
2002: Bailey Ann Marie; Mahapatra Sebabrata; Brennan Patrick J; Crick Dean C
Identification, cloning, purification, and enzymatic characterization of Mycobacterium tuberculosis 1-deoxy-D-xylulose 5-phosphate synthase.
Glycobiology 2002;12(12):813-20.
2002: Hancock Ian C; Carman Stephen; Besra Gurdyal S; Brennan Patrick J; Waite Emma
Ligation of arabinogalactan to peptidoglycan in the cell wall of Mycobacterium smegmatis requires concomitant synthesis of the two wall polymers.
Microbiology (Reading, England) 2002;148(Pt 10):3059-67.
2002: Kaur Devinder; Lowary Todd L; Vissa Varalakshmi D; Crick Dean C; Brennan Patrick J
Characterization of the epitope of anti-lipoarabinomannan antibodies as the terminal hexaarabinofuranosyl motif of mycobacterial arabinans.
Microbiology (Reading, England) 2002;148(Pt 10):3049-57.
2002: Maeda Yumi; Makino Masahiko; Crick Dean C; Mahapatra Sebabrata; Srisungnam Sopa; Takii Takemasa; Kashiwabara Yoshiko; Brennan Patrick J
Novel 33-kilodalton lipoprotein from Mycobacterium leprae.
Infection and immunity 2002;70(8):4106-11.
2002: Korduláková Jana; Gilleron Martine; Mikusova Katarína; Puzo Germain; Brennan Patrick J; Gicquel Brigitte; Jackson Mary
Definition of the first mannosylation step in phosphatidylinositol mannoside synthesis. PimA is essential for growth of mycobacteria.
The Journal of biological chemistry 2002;277(35):31335-44.
2002: Cooper Howard N; Gurcha Sudagar S; Nigou Jérôme; Brennan Patrick J; Belisle John T; Besra Gurdyal S; Young Douglas
Characterization of mycobacterial protein glycosyltransferase activity using synthetic peptide acceptors in a cell-free assay.
Glycobiology 2002;12(7):427-34.
2002: Gurcha Sudagar S; Baulard Alain R; Kremer Laurent; Locht Camille; Moody D Branch; Muhlecker Walter; Costello Catherine E; Crick Dean C; Brennan Patrick J; Besra Gurdyal S
Ppm1, a novel polyprenol monophosphomannose synthase from Mycobacterium tuberculosis.
The Biochemical journal 2002;365(Pt 2):441-50.
2002: Kremer Laurent; Dover Lynn G; Carrère Séverine; Nampoothiri K Madhavan; Lesjean Sarah; Brown Alistair K; Brennan Patrick J; Minnikin David E; Locht Camille; Besra Gurdyal S
Mycolic acid biosynthesis and enzymic characterization of the beta-ketoacyl-ACP synthase A-condensing enzyme from Mycobacterium tuberculosis.
The Biochemical journal 2002;364(Pt 2):423-30.
2002: Kremer Laurent; Gurcha Sudagar S; Bifani Pablo; Hitchen Paul G; Baulard Alain; Morris Howard R; Dell Anne; Brennan Patrick J; Besra Gurdyal S
Characterization of a putative alpha-mannosyltransferase involved in phosphatidylinositol trimannoside biosynthesis in Mycobacterium tuberculosis.
The Biochemical journal 2002;363(Pt 3):437-47.
2002: Spencer John S; Marques Maria Angela M; Lima Monica C B S; Junqueira-Kipnis Ana Paula; Gregory Bruce C; Truman Richard W; Brennan Patrick J
Antigenic specificity of the Mycobacterium leprae homologue of ESAT-6.
Infection and immunity 2002;70(2):1010-3.
2002: Torrelles J B; Ellis D; Osborne T; Hoefer A; Orme I M; Chatterjee D; Brennan P J; Cooper A M
Characterization of virulence, colony morphotype and the glycopeptidolipid of Mycobacterium avium strain 104.
Tuberculosis (Edinburgh, Scotland) 2002;82(6):293-300.
2001: Brennan P J; Vissa V D
Genomic evidence for the retention of the essential mycobacterial cell wall in the otherwise defective Mycobacterium leprae.
Leprosy review 2001;72(4):415-28.
2001: Escuyer V E; Lety M A; Torrelles J B; Khoo K H; Tang J B; Rithner C D; Frehel C; McNeil M R; Brennan P J; Chatterjee D
The role of the embA and embB gene products in the biosynthesis of the terminal hexaarabinofuranosyl motif of Mycobacterium smegmatis arabinogalactan.
The Journal of biological chemistry 2001;276(52):48854-62.
2001: Lo Re V; Brennan P J; Wadlin J; Weaver R; Nachamkin I
Infected branchial cleft cyst due to Bordetella bronchiseptica in an immunocompetent patient.
Journal of clinical microbiology 2001;39(11):4210-2.
2001: Crick D C; Mahapatra S; Brennan P J
Biosynthesis of the arabinogalactan-peptidoglycan complex of Mycobacterium tuberculosis.
Glycobiology 2001;11(9):107R-118R.
2001: Kremer L; Nampoothiri K M; Lesjean S; Dover L G; Graham S; Betts J; Brennan P J; Minnikin D E; Locht C; Besra G S
Biochemical characterization of acyl carrier protein (AcpM) and malonyl-CoA:AcpM transacylase (mtFabD), two major components of Mycobacterium tuberculosis fatty acid synthase II.
The Journal of biological chemistry 2001;276(30):27967-74.
2001: Kremer L; Dover L G; Morehouse C; Hitchin P; Everett M; Morris H R; Dell A; Brennan P J; McNeil M R; Flaherty C; Duncan K; Besra G S
Galactan biosynthesis in Mycobacterium tuberculosis. Identification of a bifunctional UDP-galactofuranosyltransferase.
The Journal of biological chemistry 2001;276(28):26430-40.
2001: Brown J R; Field R A; Barker A; Guy M; Grewal R; Khoo K H; Brennan P J; Besra G S; Chatterjec D
Synthetic mannosides act as acceptors for mycobacterial alpha1-6 mannosyltransferase.
Bioorganic & medicinal chemistry 2001;9(4):815-24.
2001: Marques M A; Mahapatra S; Sarno E N; Santos S; Spencer J S; Brennan P J; Pessolani M C
Further biochemical characterization of Mycobacterium leprae laminin-binding proteins.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.] 2001;34(4):463-70.
2001: Schulbach M C; Mahapatra S; Macchia M; Barontini S; Papi C; Minutolo F; Bertini S; Brennan P J; Crick D C
Purification, enzymatic characterization, and inhibition of the Z-farnesyl diphosphate synthase from Mycobacterium tuberculosis.
The Journal of biological chemistry 2001;276(15):11624-30.
2001: Katial R K; Hershey J; Purohit-Seth T; Belisle J T; Brennan P J; Spencer J S; Engler R J
Cell-mediated immune response to tuberculosis antigens: comparison of skin testing and measurement of in vitro gamma interferon production in whole-blood culture.
Clinical and diagnostic laboratory immunology 2001;8(2):339-45.
2001: Marques M A; Ant nio V L; Sarno E N; Brennan P J; Pessolani M C
Binding of alpha2-laminins by pathogenic and non-pathogenic mycobacteria and adherence to Schwann cells.
Journal of medical microbiology 2001;50(1):23-8.
2001: Vissa V D; Brennan P J
The genome of Mycobacterium leprae: a minimal mycobacterial gene set.
Genome biology 2001;2(8):REVIEWS1023.
2000: Brennan P J
Skin test development in leprosy: progress with first-generation skin test antigens, and an approach to the second generation.
Leprosy review 2000;71 Suppl():S50-4.
2000: Mahapatra S; Crick D C; Brennan P J
Comparison of the UDP-N-acetylmuramate:L-alanine ligase enzymes from Mycobacterium tuberculosis and Mycobacterium leprae.
Journal of bacteriology 2000;182(23):6827-30.
2000: de Melo Marques M A; Mahapatra S; Nandan D; Dick T; Sarno E N; Brennan P J; Vidal Pessolani M C
Bacterial and host-derived cationic proteins bind alpha2-laminins and enhance Mycobacterium leprae attachment to human Schwann cells.
Microbes and infection / Institut Pasteur 2000;2(12):1407-17.
2000: Crick D C; Schulbach M C; Zink E E; Macchia M; Barontini S; Besra G S; Brennan P J
Polyprenyl phosphate biosynthesis in Mycobacterium tuberculosis and Mycobacterium smegmatis.
Journal of bacteriology 2000;182(20):5771-8.
2000: Mikusová K; Yagi T; Stern R; McNeil M R; Besra G S; Crick D C; Brennan P J
Biosynthesis of the galactan component of the mycobacterial cell wall.
The Journal of biological chemistry 2000;275(43):33890-7.
2000: Jackson M; Crick D C; Brennan P J
Phosphatidylinositol is an essential phospholipid of mycobacteria.
The Journal of biological chemistry 2000;275(39):30092-9.
2000: Baulard A R; Betts J C; Engohang-Ndong J; Quan S; McAdam R A; Brennan P J; Locht C; Besra G S
Activation of the pro-drug ethionamide is regulated in mycobacteria.
The Journal of biological chemistry 2000;275(36):28326-31.
2000: Schulbach M C; Brennan P J; Crick D C
Identification of a short (C15) chain Z-isoprenyl diphosphate synthase and a homologous long (C50) chain isoprenyl diphosphate synthase in Mycobacterium tuberculosis.
The Journal of biological chemistry 2000;275(30):22876-81.
2000: Kremer L; Douglas J D; Baulard A R; Morehouse C; Guy M R; Alland D; Dover L G; Lakey J H; Jacobs W R; Brennan P J; Minnikin D E; Besra G S
Thiolactomycin and related analogues as novel anti-mycobacterial agents targeting KasA and KasB condensing enzymes in Mycobacterium tuberculosis.
The Journal of biological chemistry 2000;275(22):16857-64.
1999: Schaeffer M L; Khoo K H; Besra G S; Chatterjee D; Brennan P J; Belisle J T; Inamine J M
The pimB gene of Mycobacterium tuberculosis encodes a mannosyltransferase involved in lipoarabinomannan biosynthesis.
The Journal of biological chemistry 1999;274(44):31625-31.
1999: Brennan P J
The US-Japan Joint Leprosy Research Program meeting, San Francisco, June 28-30, 1999.
Leprosy review 1999;70(3):250-3.
1999: Brightbill H D; Libraty D H; Krutzik S R; Yang R B; Belisle J T; Bleharski J R; Maitland M; Norgard M V; Plevy S E; Smale S T; Brennan P J; Bloom B R; Godowski P J; Modlin R L
Host defense mechanisms triggered by microbial lipoproteins through toll-like receptors.
Science (New York, N.Y.) 1999;285(5428):732-6.
1999: Lautenbach E; Bilker W B; Brennan P J
Enterococcal bacteremia: risk factors for vancomycin resistance and predictors of mortality.
Infection control and hospital epidemiology : the official journal of the Society of Hospital Epidemiologists of America 1999;20(5):318-23.
1999: Phetsuksiri B; Baulard A R; Cooper A M; Minnikin D E; Douglas J D; Besra G S; Brennan P J
Antimycobacterial activities of isoxyl and new derivatives through the inhibition of mycolic acid synthesis.
Antimicrobial agents and chemotherapy 1999;43(5):1042-51.
1998: Lautenbach E; Schuster M G; Bilker W B; Brennan P J
The role of chloramphenicol in the treatment of bloodstream infection due to vancomycin-resistant Enterococcus.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 1998;27(5):1259-65.
1998: Eckstein T M; Silbaq F S; Chatterjee D; Kelly N J; Brennan P J; Belisle J T
Identification and recombinant expression of a Mycobacterium avium rhamnosyltransferase gene (rtfA) involved in glycopeptidolipid biosynthesis.
Journal of bacteriology 1998;180(21):5567-73.
1998: Silbaq F S; Cho S N; Cole S T; Brennan P J
Characterization of a 34-kilodalton protein of Mycobacterium leprae that is isologous to the immunodominant 34-kilodalton antigen of Mycobacterium paratuberculosis.
Infection and immunity 1998;66(11):5576-9.
1998: Marques M A; Chitale S; Brennan P J; Pessolani M C
Mapping and identification of the major cell wall-associated components of Mycobacterium leprae.
Infection and immunity 1998;66(6):2625-31.
1998: Lee R E; Brennan P J; Besra G S
Synthesis of beta-D-arabinofuranosyl-1-monophosphoryl polyprenols: examination of their function as mycobacterial arabinosyl transferase donors.
Bioorganic & medicinal chemistry letters 1998;8(8):951-4.
1997: Lee R E; Brennan P J; Besra G S
Mycobacterial arabinan biosynthesis: the use of synthetic arabinoside acceptors in the development of an arabinosyl transfer assay.
Glycobiology 1997;7(8):1121-8.
1997: Morgan A S; Brennan P J; Fishman N O
Impact of a vancomycin restriction policy on use and cost of vancomycin and incidence of vancomycin-resistant Enterococcus.
The Annals of pharmacotherapy 1997;31(9):970-3.
1997: Besra G S; Brennan P J
The mycobacterial cell wall: biosynthesis of arabinogalactan and lipoarabinomannan.
Biochemical Society transactions 1997;25(3):845-50.
1997: Brennan P J
Tuberculosis in the context of emerging and reemerging diseases.
FEMS immunology and medical microbiology 1997;18(4):263-9.
1997: Besra G S; Morehouse C B; Rittner C M; Waechter C J; Brennan P J
Biosynthesis of mycobacterial lipoarabinomannan.
The Journal of biological chemistry 1997;272(29):18460-6.
1997: Lee R E; Armour J W; Takayama K; Brennan P J; Besra G S
Mycolic acid biosynthesis: definition and targeting of the Claisen condensation step.
Biochimica et biophysica acta 1997;1346(3):275-84.
1997: Xin Y; Lee R E; Scherman M S; Khoo K H; Besra G S; Brennan P J; McNeil M
Characterization of the in vitro synthesized arabinan of mycobacterial cell walls.
Biochimica et biophysica acta 1997;1335(3):231-4.
1997: Belisle J T; Vissa V D; Sievert T; Takayama K; Brennan P J; Besra G S
Role of the major antigen of Mycobacterium tuberculosis in cell wall biogenesis.
Science (New York, N.Y.) 1997;276(5317):1420-2.
1997: Brennan P J; Besra G S
Structure, function and biogenesis of the mycobacterial cell wall.
Biochemical Society transactions 1997;25(1):188-94.
1996: Slayden R A; Lee R E; Armour J W; Cooper A M; Orme I M; Brennan P J; Besra G S
Antimycobacterial action of thiolactomycin: an inhibitor of fatty acid and mycolic acid synthesis.
Antimicrobial agents and chemotherapy 1996;40(12):2813-9.
1996: Brennan P J; Cho S N; Klatser P R
Bangkok Workshop on Leprosy Research. Immunodiagnostics, including skin tests.
International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association 1996;64(4 Suppl):S58-62.
1996: Pessolani M C; Brennan P J
Molecular definition and identification of new proteins of Mycobacterium leprae.
Infection and immunity 1996;64(12):5425-7.
1996: Khoo K H; Douglas E; Azadi P; Inamine J M; Besra G S; Mikusová K; Brennan P J; Chatterjee D
Truncated structural variants of lipoarabinomannan in ethambutol drug-resistant strains of Mycobacterium smegmatis. Inhibition of arabinan biosynthesis by ethambutol.
The Journal of biological chemistry 1996;271(45):28682-90.
1996: Dockrell H M; Young S K; Britton K; Brennan P J; Rivoire B; Waters M F; Lucas S B; Shahid F; Dojki M; Chiang T J; Ehsan Q; McAdam K P; Hussain R
Induction of Th1 cytokine responses by mycobacterial antigens in leprosy.
Infection and immunity 1996;64(10):4385-9.
1996: Belanger A E; Besra G S; Ford M E; Mikusová K; Belisle J T; Brennan P J; Inamine J M
The embAB genes of Mycobacterium avium encode an arabinosyl transferase involved in cell wall arabinan biosynthesis that is the target for the antimycobacterial drug ethambutol.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(21):11919-24.
1996: Khoo K H; Suzuki R; Dell A; Morris H R; McNeil M R; Brennan P J; Besra G S
Chemistry of the lyxose-containing mycobacteriophage receptors of Mycobacterium phlei/Mycobacterium smegmatis.
Biochemistry 1996;35(36):11812-9.
1996: Khoo K H; Chatterjee D; Dell A; Morris H R; Brennan P J; Draper P
Novel O-methylated terminal glucuronic acid characterizes the polar glycopeptidolipids of Mycobacterium habana strain TMC 5135.
The Journal of biological chemistry 1996;271(21):12333-42.
1996: Dobos K M; Khoo K H; Swiderek K M; Brennan P J; Belisle J T
Definition of the full extent of glycosylation of the 45-kilodalton glycoprotein of Mycobacterium tuberculosis.
Journal of bacteriology 1996;178(9):2498-506.
1996: Mikusová K; Mikus M; Besra G S; Hancock I; Brennan P J
Biosynthesis of the linkage region of the mycobacterial cell wall.
The Journal of biological chemistry 1996;271(13):7820-8.
1996: Lee R E; Brennan P J; Besra G S
Mycobacterium tuberculosis cell envelope.
Current topics in microbiology and immunology 1996;215():1-27.
1995: Mikusová K; Slayden R A; Besra G S; Brennan P J
Biogenesis of the mycobacterial cell wall and the site of action of ethambutol.
Antimicrobial agents and chemotherapy 1995;39(11):2484-9.
1995: Brennan P J; Abrutyn E
Developing policies and guidelines.
Infection control and hospital epidemiology : the official journal of the Society of Hospital Epidemiologists of America 1995;16(9):512-7.
1995: Dobos K M; Swiderek K; Khoo K H; Brennan P J; Belisle J T
Evidence for glycosylation sites on the 45-kilodalton glycoprotein of Mycobacterium tuberculosis.
Infection and immunity 1995;63(8):2846-53.
1995: Roberts A D; Sonnenberg M G; Ordway D J; Furney S K; Brennan P J; Belisle J T; Orme I M
Characteristics of protective immunity engendered by vaccination of mice with purified culture filtrate protein antigens of Mycobacterium tuberculosis.
Immunology 1995;85(3):502-8.
1995: Winter N; Triccas J A; Rivoire B; Pessolani M C; Eiglmeier K; Lim E M; Hunter S W; Brennan P J; Britton W J
Characterization of the gene encoding the immunodominant 35 kDa protein of Mycobacterium leprae.
Molecular microbiology 1995;16(5):865-76.
1995: Khoo K H; Dell A; Morris H R; Brennan P J; Chatterjee D
Inositol phosphate capping of the nonreducing termini of lipoarabinomannan from rapidly growing strains of Mycobacterium.
The Journal of biological chemistry 1995;270(21):12380-9.
1995: Norris A H; Reilly J P; Edelstein P H; Brennan P J; Schuster M G
Chloramphenicol for the treatment of vancomycin-resistant enterococcal infections.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 1995;20(5):1137-44.
1995: Besra G S; Khoo K H; McNeil M R; Dell A; Morris H R; Brennan P J
A new interpretation of the structure of the mycolyl-arabinogalactan complex of Mycobacterium tuberculosis as revealed through characterization of oligoglycosylalditol fragments by fast-atom bombardment mass spectrometry and 1H nuclear magnetic resonance spectroscopy.
Biochemistry 1995;34(13):4257-66.
1995: Deng L; Mikusová K; Robuck K G; Scherman M; Brennan P J; McNeil M R
Recognition of multiple effects of ethambutol on metabolism of mycobacterial cell envelope.
Antimicrobial agents and chemotherapy 1995;39(3):694-701.
1995: Sastry V; Brennan P J; Levy M M; Fishman N; Friedman A L; Naji A; Barker C F; Brayman K L
Vancomycin-resistant enterococci: an emerging pathogen in immunosuppressed transplant recipients.
Transplantation proceedings 1995;27(1):954-5.
1995: Shulkin D J; Brennan P J
The cost of caring for patients with tuberculosis: planning for a disease on the rise.
American journal of infection control 1995;23(1):1-4.
1995: Brennan P J; Nikaido H
The envelope of mycobacteria.
Annual review of biochemistry 1995;64():29-63.
1995: Aspinall G O; Chatterjee D; Brennan P J
The variable surface glycolipids of mycobacteria: structures, synthesis of epitopes, and biological properties.
Advances in carbohydrate chemistry and biochemistry 1995;51():169-242.
1994: Besra G S; Sievert T; Lee R E; Slayden R A; Brennan P J; Takayama K
Identification of the apparent carrier in mycolic acid synthesis.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(26):12735-9.
1994: Besra G S; Gurcha S S; Khoo K H; Morris H R; Dell A; Hamid M E; Minnikin D E; Goodfellow M; Brennan P J
Characterization of the specific antigenicity of representatives of M. senegalense and related bacteria.
Zentralblatt für Bakteriologie : international journal of medical microbiology 1994;281(4):415-32.
1994: Mills J A; McNeil M R; Belisle J T; Jacobs W R; Brennan P J
Loci of Mycobacterium avium ser2 gene cluster and their functions.
Journal of bacteriology 1994;176(16):4803-8.
1994: Pessolani M C; Smith D R; Rivoire B; McCormick J; Hefta S A; Cole S T; Brennan P J
Purification, characterization, gene sequence, and significance of a bacterioferritin from Mycobacterium leprae.
The Journal of experimental medicine 1994;180(1):319-27.
1994: Rivoire B; Pessolani M C; Bozic C M; Hunter S W; Hefta S A; Mehra V; Brennan P J
Chemical definition, cloning, and expression of the major protein of the leprosy bacillus.
Infection and immunity 1994;62(6):2417-25.
1994: Orme I M; Furney S K; Skinner P S; Roberts A D; Brennan P J; Russell D G; Shiratsuchi H; Ellner J J; Weiser W Y
Inhibition of growth Mycobacterium avium in murine and human mononuclear phagocytes by migration inhibitory factor.
Infection and immunity 1994;62(5):2141.
1994: Prinzis S; Rivoire B; Brennan P J
Search for the molecular basis of morphological variation in Mycobacterium avium.
Infection and immunity 1994;62(5):1946-51.
1994: McNeil M R; Robuck K G; Harter M; Brennan P J
Enzymatic evidence for the presence of a critical terminal hexa-arabinoside in the cell walls of Mycobacterium tuberculosis.
Glycobiology 1994;4(2):165-73.
1994: Belisle J T; Brennan P J
Molecular basis of colony morphology in Mycobacterium avium.
Research in microbiology 1994;145(3):237-42.
1994: Besra G S; Khoo K H; Belisle J T; McNeil M R; Morris H R; Dell A; Brennan P J
New pyruvylated, glycosylated acyltrehaloses from Mycobacterium smegmatis strains, and their implications for phage resistance in mycobacteria.
Carbohydrate research 1994;251():99-114.
1994: Brennan P J; Chatterjee D; Fujiwara T; Cho S N
Leprosy-specific neoglycoconjugates: synthesis and application to serodiagnosis of leprosy.
Methods in enzymology 1994;242():27-37.
1993: Seltzer E; Schulman K A; Brennan P J; Lynn L A
Patient attitudes toward rooming with persons with HIV infection.
The Journal of family practice 1993;37(6):564-8.
1993: Prinzis S; Chatterjee D; Brennan P J
Structure and antigenicity of lipoarabinomannan from Mycobacterium bovis BCG.
Journal of general microbiology 1993;139(11):2649-58.
1993: Daffe M; McNeil M; Brennan P J
Major structural features of the cell wall arabinogalactans of Mycobacterium, Rhodococcus, and Nocardia spp.
Carbohydrate research 1993;249(2):383-98.
1993: Besra G S; McNeil M R; Khoo K H; Dell A; Morris H R; Brennan P J
Trehalose-containing lipooligosaccharides of Mycobacterium gordonae: presence of a mono-O-methyltetra-O-acyltrehalose "core" and branching in the oligosaccharide backbone.
Biochemistry 1993;32(47):12705-14.
1993: Chatterjee D; Khoo K H; McNeil M R; Dell A; Morris H R; Brennan P J
Structural definition of the non-reducing termini of mannose-capped LAM from Mycobacterium tuberculosis through selective enzymatic degradation and fast atom bombardment-mass spectrometry.
Glycobiology 1993;3(5):497-506.
1993: Schuster M G; Brennan P J; Edelstein P
Persistent bacteremia with Erysipelothrix rhusiopathiae in a hospitalized patient.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 1993;17(4):783-4.
1993: Pessolani M C; Hunter S W; Brennan P J
Relationship between host histones and armadillo-derived Mycobacterium leprae.
International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association 1993;61(3):381-8.
1993: Belisle J T; Klaczkiewicz K; Brennan P J; Jacobs W R; Inamine J M
Rough morphological variants of Mycobacterium avium. Characterization of genomic deletions resulting in the loss of glycopeptidolipid expression.
The Journal of biological chemistry 1993;268(14):10517-23.
1993: Belisle J T; McNeil M R; Chatterjee D; Inamine J M; Brennan P J
Expression of the core lipopeptide of the glycopeptidolipid surface antigens in rough mutants of Mycobacterium avium.
The Journal of biological chemistry 1993;268(14):10510-6.
1993: Orme I M; Furney S K; Skinner P S; Roberts A D; Brennan P J; Russell D G; Shiratsuchi H; Ellner J J; Weiser W Y
Inhibition of growth of Mycobacterium avium in murine and human mononuclear phagocytes by migration inhibitory factor.
Infection and immunity 1993;61(1):338-42.
1993: Besra G S; McNeil M R; Rivoire B; Khoo K H; Morris H R; Dell A; Brennan P J
Further structural definition of a new family of glycopeptidolipids from Mycobacterium xenopi.
Biochemistry 1993;32(1):347-55.
1992: Aspinall G O; Gammon D W; Sood R K; Chatterjee D; Rivoire B; Brennan P J
Structures of the glycopeptidolipid antigens of serovars 25 and 26 of the Mycobacterium avium serocomplex, synthesis of allyl glycosides of the outer disaccharide units and serology of the derived neoglycoproteins.
Carbohydrate research 1992;237():57-77.
1992: Pessolani M C; Brennan P J
Mycobacterium leprae produces extracellular homologs of the antigen 85 complex.
Infection and immunity 1992;60(11):4452-9.
1992: Besra G S; Bolton R C; McNeil M R; Ridell M; Simpson K E; Glushka J; van Halbeek H; Brennan P J; Minnikin D E
Structural elucidation of a novel family of acyltrehaloses from Mycobacterium tuberculosis.
Biochemistry 1992;31(40):9832-7.
1992: Khanolkar-Young S; Kolk A H; Andersen A B; Bennedsen J; Brennan P J; Rivoire B; Kuijper S; McAdam K P; Abe C; Batra H V
Results of the third immunology of leprosy/immunology of tuberculosis antimycobacterial monoclonal antibody workshop.
Infection and immunity 1992;60(9):3925-7.
1992: Besra G S; McNeil M R; Brennan P J
Characterization of the specific antigenicity of Mycobacterium fortuitum.
Biochemistry 1992;31(28):6504-9.
1992: Barnes P F; Chatterjee D; Abrams J S; Lu S; Wang E; Yamamura M; Brennan P J; Modlin R L
Cytokine production induced by Mycobacterium tuberculosis lipoarabinomannan. Relationship to chemical structure.
Journal of immunology (Baltimore, Md. : 1950) 1992;149(2):541-7.
1992: Lee B Y; Hefta S A; Brennan P J
Characterization of the major membrane protein of virulent Mycobacterium tuberculosis.
Infection and immunity 1992;60(5):2066-74.
1992: Barnes P F; Chatterjee D; Brennan P J; Rea T H; Modlin R L
Tumor necrosis factor production in patients with leprosy.
Infection and immunity 1992;60(4):1441-6.
1992: Chatterjee D; Lowell K; Rivoire B; McNeil M R; Brennan P J
Lipoarabinomannan of Mycobacterium tuberculosis. Capping with mannosyl residues in some strains.
The Journal of biological chemistry 1992;267(9):6234-9.
1992: Chatterjee D; Hunter S W; McNeil M; Brennan P J
Lipoarabinomannan. Multiglycosylated form of the mycobacterial mannosylphosphatidylinositols.
The Journal of biological chemistry 1992;267(9):6228-33.
1992: Chatterjee D; Roberts A D; Lowell K; Brennan P J; Orme I M
Structural basis of capacity of lipoarabinomannan to induce secretion of tumor necrosis factor.
Infection and immunity 1992;60(3):1249-53.
1992: Barnes P F; Mehra V; Rivoire B; Fong S J; Brennan P J; Voegtline M S; Minden P; Houghten R A; Bloom B R; Modlin R L
Immunoreactivity of a 10-kDa antigen of Mycobacterium tuberculosis.
Journal of immunology (Baltimore, Md. : 1950) 1992;148(6):1835-40.
1992: Tsang A Y; Denner J C; Brennan P J; McClatchy J K
Clinical and epidemiological importance of typing of Mycobacterium avium complex isolates.
Journal of clinical microbiology 1992;30(2):479-84.
1992: Denner J C; Tsang A Y; Chatterjee D; Brennan P J
Comprehensive approach to identification of serovars of Mycobacterium avium complex.
Journal of clinical microbiology 1992;30(2):473-8.
1992: Mehra V; Bloom B R; Bajardi A C; Grisso C L; Sieling P A; Alland D; Convit J; Fan X D; Hunter S W; Brennan P J
A major T cell antigen of Mycobacterium leprae is a 10-kD heat-shock cognate protein.
The Journal of experimental medicine 1992;175(1):275-84.
1992: Orme I M; Miller E S; Roberts A D; Furney S K; Griffin J P; Dobos K M; Chi D; Rivoire B; Brennan P J
T lymphocytes mediating protection and cellular cytolysis during the course of Mycobacterium tuberculosis infection. Evidence for different kinetics and recognition of a wide spectrum of protein antigens.
Journal of immunology (Baltimore, Md. : 1950) 1992;148(1):189-96.
1991: Belisle J T; Pascopella L; Inamine J M; Brennan P J; Jacobs W R
Isolation and expression of a gene cluster responsible for biosynthesis of the glycopeptidolipid antigens of Mycobacterium avium.
Journal of bacteriology 1991;173(21):6991-7.
1991: Aspinall G O; Khare N K; Sood R K; Chatterjee D; Rivoire B; Brennan P J
Structure of the glycopeptidolipid antigen of serovar 20 of the Mycobacterium avium serocomplex, synthesis of allyl glycosides of the outer di- and tri-saccharide units of the antigens of serovars 14 and 20, and serology of the derived neoglycoproteins.
Carbohydrate research 1991;216():357-73.
1991: Aspinall G O; Crane A M; Gammon D W; Ibrahim I H; Khare N K; Chatterjee D; Rivoire B; Brennan P J
Synthesis of allyl glycosides for conversion into neoglycoproteins bearing epitopes of mycobacterial glycolipid antigens.
Carbohydrate research 1991;216():337-55.
1991: Besra G S; McNeil M; Minnikin D E; Portaels F; Ridell M; Brennan P J
Structural elucidation and antigenicity of a novel phenolic glycolipid antigen from Mycobacterium haemophilum.
Biochemistry 1991;30(31):7772-7.
1991: McNeil M; Daffe M; Brennan P J
Location of the mycolyl ester substituents in the cell walls of mycobacteria.
The Journal of biological chemistry 1991;266(20):13217-23.
1991: Lee B Y; Chatterjee D; Bozic C M; Brennan P J; Cohn D L; Bales J D; Harrison S M; Andron L A; Orme I M
Prevalence of serum antibody to the type-specific glycopeptidolipid antigens of Mycobacterium avium in human immunodeficiency virus-positive and -negative individuals.
Journal of clinical microbiology 1991;29(5):1026-9.
1991: Chatterjee D; Bozic C M; McNeil M; Brennan P J
Structural features of the arabinan component of the lipoarabinomannan of Mycobacterium tuberculosis.
The Journal of biological chemistry 1991;266(15):9652-60.
1991: McNeil M R; Brennan P J
Structure, function and biogenesis of the cell envelope of mycobacteria in relation to bacterial physiology, pathogenesis and drug resistance; some thoughts and possibilities arising from recent structural information.
Research in microbiology 1991;142(4):451-63.
1991: Chan J; Fan X D; Hunter S W; Brennan P J; Bloom B R
Lipoarabinomannan, a possible virulence factor involved in persistence of Mycobacterium tuberculosis within macrophages.
Infection and immunity 1991;59(5):1755-61.
1991: Daffe M; McNeil M; Brennan P J
Novel type-specific lipooligosaccharides from Mycobacterium tuberculosis.
Biochemistry 1991;30(2):378-88.
1991: Daffe M; Cho S N; Chatterjee D; Brennan P J
Chemical synthesis and seroreactivity of a neoantigen containing the oligosaccharide hapten of the Mycobacterium tuberculosis-specific phenolic glycolipid.
The Journal of infectious diseases 1991;163(1):161-8.
1990: McNeil M; Daffe M; Brennan P J
Evidence for the nature of the link between the arabinogalactan and peptidoglycan of mycobacterial cell walls.
The Journal of biological chemistry 1990;265(30):18200-6.
1990: Hunter S W; Rivoire B; Mehra V; Bloom B R; Brennan P J
The major native proteins of the leprosy bacillus.
The Journal of biological chemistry 1990;265(24):14065-8.
1990: Barnes P F; Fong S J; Brennan P J; Twomey P E; Mazumder A; Modlin R L
Local production of tumor necrosis factor and IFN-gamma in tuberculous pleuritis.
Journal of immunology (Baltimore, Md. : 1950) 1990;145(1):149-54.
1990: Hunter S W; Brennan P J
Evidence for the presence of a phosphatidylinositol anchor on the lipoarabinomannan and lipomannan of Mycobacterium tuberculosis.
The Journal of biological chemistry 1990;265(16):9272-9.
1990: Daffe M; Brennan P J; McNeil M
Predominant structural features of the cell wall arabinogalactan of Mycobacterium tuberculosis as revealed through characterization of oligoglycosyl alditol fragments by gas chromatography/mass spectrometry and by 1H and 13C NMR analyses.
The Journal of biological chemistry 1990;265(12):6734-43.
1990: Hirschfield G R; McNeil M; Brennan P J
Peptidoglycan-associated polypeptides of Mycobacterium tuberculosis.
Journal of bacteriology 1990;172(2):1005-13.
1989: Barnes P F; Mehra V; Hirschfield G R; Fong S J; Abou-Zeid C; Rook G A; Hunter S W; Brennan P J; Modlin R L
Characterization of T cell antigens associated with the cell wall protein-peptidoglycan complex of Mycobacterium tuberculosis.
Journal of immunology (Baltimore, Md. : 1950) 1989;143(8):2656-62.
1989: Rivoire B; Ranchoff B J; Chatterjee D; Gaylord H; Tsang A Y; Kolk A H; Aspinall G O; Brennan P J
Generation of monoclonal antibodies to the specific sugar epitopes of Mycobacterium avium complex serovars.
Infection and immunity 1989;57(10):3147-58.
1989: Belisle J T; Brennan P J
Chemical basis of rough and smooth variation in mycobacteria.
Journal of bacteriology 1989;171(6):3465-70.
1989: Hunter S W; McNeil M; Modlin R L; Mehra V; Bloom B R; Brennan P J
Isolation and characterization of the highly immunogenic cell wall-associated protein of Mycobacterium leprae.
Journal of immunology (Baltimore, Md. : 1950) 1989;142(8):2864-72.
1989: Jardine I; Scanlan G; McNeil M; Brennan P J
Plasma desorption mass spectrometric analysis of mycobacterial glycolipids.
Analytical chemistry 1989;61(5):416-22.
1989: Brennan P J
Structure of mycobacteria: recent developments in defining cell wall carbohydrates and proteins.
Reviews of infectious diseases 1989;11 Suppl 2():S420-30.
1989: Chatterjee D; Bozic C M; Knisley C; Cho S N; Brennan P J
Phenolic glycolipids of Mycobacterium bovis: new structures and synthesis of a corresponding seroreactive neoglycoprotein.
Infection and immunity 1989;57(2):322-30.
1989: Chatterjee D; Hunter S W; McNeil M; Jardine I; Brennan P J
Structure and function of mycobacterial glycolipids and glycopeptidolipids.
Acta leprologica 1989;7 Suppl 1():81-4.
1988: Chatterjee D; Cho S N; Stewart C; Douglas J T; Fujiwara T; Brennan P J
Synthesis and immunoreactivity of neoglycoproteins containing the trisaccharide unit of phenolic glycolipid I of Mycobacterium leprae.
Carbohydrate research 1988;183(2):241-60.
1988: Bozic C M; McNeil M; Chatterjee D; Jardine I; Brennan P J
Further novel amido sugars within the glycopeptidolipid antigens of Mycobacterium avium.
The Journal of biological chemistry 1988;263(29):14984-91.
1988: Camphausen R T; Jones R L; Brennan P J
Antigenic relationship between Mycobacterium paratuberculosis and Mycobacterium avium.
American journal of veterinary research 1988;49(8):1307-10.
1988: McNeil M; Gaylord H; Brennan P J
N-formylkansosaminyl-(1----3)-2-O-methyl-D-rhamnopyranose: the type-specific determinant of serovariant 14 of the Mycobacterium avium complex.
Carbohydrate research 1988;177():185-98.
1988: Hunter S W; Barr V L; McNeil M; Jardine I; Brennan P J
Trehalose-containing lipooligosaccharide antigens of Mycobacterium sp.: presence of a mono-O-methyltri-O-acyltrehalose "core".
Biochemistry 1988;27(5):1549-56.
1988: Chatterjee D; Bozic C; Aspinall G O; Brennan P J
Glucuronic acid- and branched sugar-containing glycolipid antigens of Mycobacterium avium.
The Journal of biological chemistry 1988;263(9):4092-7.
1988: Bloom B R; Mehra V; Melancon-Kaplan J; Castes M; Convit J; Brennan P J; Rea T H; Modlin R L
Mechanisms of immunological unresponsiveness in the spectra of leprosy and leishmaniasis.
Advances in experimental medicine and biology 1988;239():263-78.
1987: Camphausen R T; McNeil M; Jardine I; Brennan P J
Location of acyl groups of trehalose-containing lipooligosaccharides of mycobacteria.
Journal of bacteriology 1987;169(12):5473-80.
1987: Gaylord H; Brennan P J; Young D B; Buchanan T M
Most Mycobacterium leprae carbohydrate-reactive monoclonal antibodies are directed to lipoarabinomannan.
Infection and immunity 1987;55(11):2860-3.
1987: McNeil M; Wallner S J; Hunter S W; Brennan P J
Demonstration that the galactosyl and arabinosyl residues in the cell-wall arabinogalactan of Mycobacterium leprae and Mycobacterium tuberculosis are furanoid.
Carbohydrate research 1987;166(2):299-308.
1987: McNeil M; Tsang A Y; McClatchy J K; Stewart C; Jardine I; Brennan P J
Definition of the surface antigens of Mycobacterium malmoense and use in studying the etiology of a form of mycobacteriosis.
Journal of bacteriology 1987;169(7):3312-20.
1987: Gaylord H; Brennan P J
Leprosy and the leprosy bacillus: recent developments in characterization of antigens and immunology of the disease.
Annual review of microbiology 1987;41():645-75.
1986: Jardine I; Hunter S W; Brennan P J; McNeal C J; Macfarlane R D
Heterogeneity of bacterial antigenic lipooligosaccharides determined by californium-252 plasma desorption mass spectrometry.
Biomedical & environmental mass spectrometry 1986;13(6):273-6.
1985: Knisley C V; Damato J J; McClatchy J K; Brennan P J
Rapid and sensitive identification of Mycobacterium tuberculosis.
Journal of clinical microbiology 1985;22(5):761-7.
1985: Hunter S W; Jardine I; Yanagihara D L; Brennan P J
Trehalose-containing lipooligosaccharides from mycobacteria: structures of the oligosaccharide segments and recognition of a unique N-acylkanosamine-containing epitope.
Biochemistry 1985;24(11):2798-805.
1985: Yanagihara D L; Barr V L; Knisley C V; Tsang A Y; McClatchy J K; Brennan P J
Enzyme-linked immunosorbent assay of glycolipid antigens for identification of mycobacteria.
Journal of clinical microbiology 1985;21(4):569-74.
1984: Mehra V; Brennan P J; Rada E; Convit J; Bloom B R
Lymphocyte suppression in leprosy induced by unique M. leprae glycolipid.
Nature 1984;308(5955):194-6.

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