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Stephen Wring

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Publications

TOP 3
Robert T Jacobs; Matthew Jenks; Bakela Nare; Robert A Noe; Matthew D Orr; Joe B Perales; Jacob J Plattner; Jessica M Sligar; Stephen A Wring; Nigel Yarlett; Yong-Kang Zhang; Cyrus J Bacchi; Daitao Chen; Yvonne Freund; Eric G Gaukel; Robert Don
Benzoxaboroles: a new class of potential drugs for human African trypanosomiasis.
Robert T Jacobs; Matthew X Jenks; Marcel Kaiser; Luke T Mercer; Bakela Nare; Robert A Noe; Matthew D Orr; Jennifer Owens; Robin Parham; Jacob J Plattner; Ryan Randolph; Cindy Rewerts; Ivan Scandale; Jessica M Sligar; Stephen A Wring; Nigel Yarlett; Y-K Zhang; Tsutomu Akama; Cyrus J Bacchi; Beth Beaudet; Tana S Bowling; Reto Brun; Daitao Chen; Charles Ding; Yvonne Freund; Eric Gaukel; Robert Don
SCYX-7158, an orally-active benzoxaborole for the treatment of stage 2 human African trypanosomiasis.
Joe B Perales; Jennifer Freeman; Cyrus J Bacchi; Tana Bowling; Robert Don; Eric Gaukel; Luke Mercer; Bakela Nare; Tien M Nguyen; Robert A Noe; Ryan Randolph; Cindy Rewerts; Stephen A Wring; Nigel Yarlett; Joseph A Moore; Robert T Jacobs
SAR of 2-amino and 2,4-diamino pyrimidines with in vivo efficacy against Trypanosoma brucei.

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All Publications

2011: Robert T Jacobs; Matthew Jenks; Bakela Nare; Robert A Noe; Matthew D Orr; Joe B Perales; Jacob J Plattner; Jessica M Sligar; Stephen A Wring; Nigel Yarlett; Yong-Kang Zhang; Cyrus J Bacchi; Daitao Chen; Yvonne Freund; Eric G Gaukel; Robert Don
Benzoxaboroles: a new class of potential drugs for human African trypanosomiasis.
Future medicinal chemistry 2011;3(10):1259-78.
2011: Robert T Jacobs; Matthew X Jenks; Marcel Kaiser; Luke T Mercer; Bakela Nare; Robert A Noe; Matthew D Orr; Jennifer Owens; Robin Parham; Jacob J Plattner; Ryan Randolph; Cindy Rewerts; Ivan Scandale; Jessica M Sligar; Stephen A Wring; Nigel Yarlett; Y-K Zhang; Tsutomu Akama; Cyrus J Bacchi; Beth Beaudet; Tana S Bowling; Reto Brun; Daitao Chen; Charles Ding; Yvonne Freund; Eric Gaukel; Robert Don
SCYX-7158, an orally-active benzoxaborole for the treatment of stage 2 human African trypanosomiasis.
PLoS neglected tropical diseases 2011;5(6):e1151.
2011: Joe B Perales; Jennifer Freeman; Cyrus J Bacchi; Tana Bowling; Robert Don; Eric Gaukel; Luke Mercer; Bakela Nare; Tien M Nguyen; Robert A Noe; Ryan Randolph; Cindy Rewerts; Stephen A Wring; Nigel Yarlett; Joseph A Moore; Robert T Jacobs
SAR of 2-amino and 2,4-diamino pyrimidines with in vivo efficacy against Trypanosoma brucei.
Bioorganic & medicinal chemistry letters 2011;21(10):2816-9.
2008: Rana Rais; Pablo M Gonzalez; zheng xiaowan; Stephen A Wring; James E. Polli
Method to screen substrates of apical sodium-dependent bile acid transporter.
The AAPS journal 2008;10(4):596-605.
2008: Richard W Price; Robin Parham; Jing Lu Kroll; Stephen A Wring; Brian Baker; Jeff Sailstad; Rebecca Hoh; Teri Liegler; Serena Spudich; Daniel R Kuritzkes; Steven G Deeks
Enfuvirtide cerebrospinal fluid (CSF) pharmacokinetics and potential use in defining CSF HIV-1 origin.
Antiviral therapy 2008;13(3):369-74.
2007: John J Dwyer; Karen L Wilson; Donna K Davison; Stephanie A Freel; Jennifer E Seedorff; Stephen A Wring; Nicolai A Tvermoes; Thomas J Matthews; Michael L Greenberg; Mary K Delmedico
Design of helical, oligomeric HIV-1 fusion inhibitor peptides with potent activity against enfuvirtide-resistant virus.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(31):12772-7.
2006: Anand Balakrishnan; Stephen A Wring; James E. Polli
Interaction of native bile acids with human apical sodium-dependent bile acid transporter (hASBT): influence of steroidal hydroxylation pattern and C-24 conjugation.
Pharmaceutical research 2006;23(7):1451-9.
2006: Anand Balakrishnan; Stephen A Wring; Andrew Coop; James E. Polli
Influence of charge and steric bulk in the C-24 region on the interaction of bile acids with human apical sodium-dependent bile acid transporter.
Molecular pharmaceutics 2006;3(3):282-92.
2006: Marianne Harris; Ruth Joy; Gerene Larsen; Monica Valyi; Ekaterina Walker; Lloyd W Frick; Robin M Palmatier; Stephen A Wring; Julio S G Montaner
Enfuvirtide plasma levels and injection site reactions using a needle-free gas-powered injection system (Biojector).
AIDS (London, England) 2006;20(5):719-23.
2004: Kelly M Mahar Doan; Stephen A Wring; Larry J Shampine; Kelly H Jordan; James P Bishop; John Kratz; Eric Yang; Cosette J Serabjit-Singh; Kimberly K Adkison; Joseph W Polli
Steady-state brain concentrations of antihistamines in rats: interplay of membrane permeability, P-glycoprotein efflux and plasma protein binding.
Pharmacology 2004;72(2):92-8.
2004: Vijay K Gombar; Joseph W Polli; Joan E Humphreys; Stephen A Wring; Cosette S Serabjit-Singh
Predicting P-glycoprotein substrates by a quantitative structure-activity relationship model.
Journal of pharmaceutical sciences 2004;93(4):957-68.
2003: Sanna Tolle-Sander; Jarkko Rautio; Stephen A Wring; Joseph W Polli; James E. Polli
Midazolam exhibits characteristics of a highly permeable P-glycoprotein substrate.
Pharmaceutical research 2003;20(5):757-64.
2002: Kelly M Mahar Doan; Joan E Humphreys; Lindsey O Webster; Stephen A Wring; Larry J Shampine; Cosette J Serabjit-Singh; Kimberly K Adkison; Joseph W Polli
Passive permeability and P-glycoprotein-mediated efflux differentiate central nervous system (CNS) and non-CNS marketed drugs.
The Journal of pharmacology and experimental therapeutics 2002;303(3):1029-37.
2002: Stephen A Wring; Ivin S Silver; Cosette J Serabjit-Singh
Automated quantitative and qualitative analysis of metabolic stability: a process for compound selection during drug discovery.
Methods in enzymology 2002;357():285-95.
2001: Joseph W Polli; Stephen A Wring; Joan E Humphreys; L Huang; J B Morgan; Lindsey O Webster; C S Serabjit-Singh
Rational use of in vitro P-glycoprotein assays in drug discovery.
The Journal of pharmacology and experimental therapeutics 2001;299(2):620-8.
2001: L Huang; Stephen A Wring; JL Woolley; Kenneth Brouwer; Cosette J Serabjit-Singh; Joseph W Polli
Induction of P-glycoprotein and cytochrome P450 3A by HIV protease inhibitors.
Drug metabolism and disposition: the biological fate of chemicals 2001;29(5):754-60.
2000: Kimberley A Lentz; Joseph W Polli; Stephen A Wring; Joan E Humphreys; James E. Polli
Influence of passive permeability on apparent P-glycoprotein kinetics.
Pharmaceutical research 2000;17(12):1456-60.
2000: Kathryn B Kenney; Stephen A Wring; R M Carr; G N Wells; John A Dunn
Simultaneous determination of zidovudine and lamivudine in human serum using HPLC with tandem mass spectrometry.
Journal of pharmaceutical and biomedical analysis 2000;22(6):967-83.
1999: Stephen A Wring; Katherine E Kilpatrick; Jeff T Hutchins; Sam M. Witherspoon; Byron Ellis; W N Jenner; Cosette J Serabjit-Singh
Shorter development of immunoassay for drugs: application of the novel RIMMS technique enables rapid production of monoclonal antibodies to ranitidine.
Journal of pharmaceutical and biomedical analysis 1999;19(5):695-707.
1998: Stephen A Wring; A Terry; R Causon; W N Jenner
The electroanalysis of mannitol, xylose and lactulose at copper electrodes: voltammetric studies and bioanalysis in human urine by means of HPLC with electrochemical detection.
Journal of pharmaceutical and biomedical analysis 1998;16(7):1213-24.
1997: Katherine E Kilpatrick; Stephen A Wring; D H Walker; Macklin Michael; J Alan Payne; Jui-Lan Su; BR Champion; B Caterson; G D McIntyre
Rapid development of affinity matured monoclonal antibodies using RIMMS.
Hybridoma 1997;16(4):381-9.
1994: Stephen A Wring; R M O'Neill; J L Williams; W N Jenner; M J Daniel; M R Gray; J J Newman; G N Wells; D R Sutherland
The production and evaluation of a radioligand and antiserum for the radioimmunoassay of subnanogram per millilitre concentrations of lamivudine.
Journal of pharmaceutical and biomedical analysis 1994;12(12):1573-83.
1994: Stephen A Wring; R M O'Neill; J L Williams; H L Birch; C P Goddard; P D Andrew; W N Jenner
Radioimmunoassay for the determination of alosetron in human urine and saliva.
The Analyst 1994;119(11):2395-401.
1994: Stephen A Wring; R M Rooney; C P Goddard; I Waterhouse; W N Jenner
A sensitive radioimmunoassay, combined with solid-phase extraction, for the sub-nanogram per ml determination of ondansetron in human plasma.
Journal of pharmaceutical and biomedical analysis 1994;12(3):361-71.