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Christoph Wruck

Research Profile

Chemicals & Drugs

Anatomy

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Physiology

Signal Transduction

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Animal Disease Models

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Tolga Taha Sönmez; Alexandra Vinogradov; Christoph J Wruck; Fatih Zor; Frank Hölzle; Nisreen Kweider; Elisa Anamaria Liehn; Sebastian Lippross; Mustafa Naziroglu; Thomas Pufe; Mersedeh Tohidnezhad
The effect of platelet rich plasma on angiogenesis in ischemic flaps in VEGFR2-luc mice.
Jon Dang; Athanasius Fragoulis; Markus Kipp; Thomas Pufe; Christian Rosen; Cordian Beyer; Lars-Ove Brandenburg; Christoph J Wruck
Nrf2 expression by neurons, astroglia, and microglia in the cerebral cortical penumbra of ischemic rats.
Alexander Slowik; Christoph J Wruck; Anne Elfgen; Sandra Jansen; Julika Merres; Fabian Mohr; Thomas Pufe; Lars-Ove Brandenburg
Involvement of formyl peptide receptors in receptor for advanced glycation end products (RAGE)--and amyloid beta 1-42-induced signal transduction in glial cells.

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All Publications

2013: Tolga Taha Sönmez; Alexandra Vinogradov; Christoph J Wruck; Fatih Zor; Frank Hölzle; Nisreen Kweider; Elisa Anamaria Liehn; Sebastian Lippross; Mustafa Naziroglu; Thomas Pufe; Mersedeh Tohidnezhad
The effect of platelet rich plasma on angiogenesis in ischemic flaps in VEGFR2-luc mice.
Biomaterials 2013;34(11):2674-82.
2012: Jon Dang; Athanasius Fragoulis; Markus Kipp; Thomas Pufe; Christian Rosen; Cordian Beyer; Lars-Ove Brandenburg; Christoph J Wruck
Nrf2 expression by neurons, astroglia, and microglia in the cerebral cortical penumbra of ischemic rats.
Journal of molecular neuroscience : MN 2012;46(3):578-84.
2012: Alexander Slowik; Christoph J Wruck; Anne Elfgen; Sandra Jansen; Julika Merres; Fabian Mohr; Thomas Pufe; Lars-Ove Brandenburg
Involvement of formyl peptide receptors in receptor for advanced glycation end products (RAGE)--and amyloid beta 1-42-induced signal transduction in glial cells.
Molecular neurodegeneration 2012;7():55.
2012: Nisreen Kweider; Thomas Pufe; Werner Rath; Christoph J Wruck; Rainer Beckmann; Berthold Huppertz; Mamed Kadyrov
A role for Nrf2 in redox signalling of the invasive extravillous trophoblast in severe early onset IUGR associated with preeclampsia.
PloS one 2012;7(10):e47055.
2012: Mersedeh Tohidnezhad; Deike Varoga; Christoph J Wruck; Jorg Bornemann; Manfred Bovi; Lars-Ove Brandenburg; Astrid Houben; Rainer Podschun; Thomas Pufe; Benita Hermanns Sachweh; Andreas Seekamp; Alexander Slowik; Tolga Taha Sönmez; Sebastian Lippross
Platelets display potent antimicrobial activity and release human beta-defensin 2.
Platelets 2012;23(3):217-23.
2011: Christoph J Wruck; Lars-Ove Brandenburg; Mamed Kadyrov; Mersedeh Tohidnezhad; Anja Wruck; Thomas Pufe
Impact of Nrf2 on esophagus epithelium cornification.
International journal of dermatology 2011;50(11):1362-5.
2011: Sebastian Lippross; Bjoern Moeller; Thomas Pufe; Andreas Seekamp; Nadine Steubesand; Mersedeh Tohidnezhad; Holger Haas; Bodo Kurz; Christoph J Wruck; Deike Varoga
Intraarticular injection of platelet-rich plasma reduces inflammation in a pig model of rheumatoid arthritis of the knee joint.
Arthritis and rheumatism 2011;63(11):3344-53.
2011: Caroline Bauch; Eric Fabian; Susanne N Kolle; Christina Pachel; Tzutzuy Ramirez; Benjamin Wiench; Christoph J Wruck; Bennard van Ravenzwaay; Robert LANDSIEDEL
Intralaboratory validation of four in vitro assays for the prediction of the skin sensitizing potential of chemicals.
Toxicology in vitro : an international journal published in association with BIBRA 2011;25(6):1162-8.
2011: Mersedeh Tohidnezhad; Deike Varoga; Rainer Podschun; Christoph J Wruck; Andreas Seekamp; Lars-Ove Brandenburg; Thomas Pufe; Sebastian Lippross
Thrombocytes are effectors of the innate immune system releasing human beta defensin-3.
Injury 2011;42(7):682-6.
2011: Mersedeh Tohidnezhad; Deike Varoga; Christoph J Wruck; Lars-Ove Brandenburg; A Seekamp; M Shakibaei; Tolga Taha Sönmez; Thomas Pufe; S Lippross
Platelet-released growth factors can accelerate tenocyte proliferation and activate the anti-oxidant response element.
Histochemistry and cell biology 2011;135(5):453-60.
2011: Christoph J Wruck; Konrad Streetz; Goran Pavic; Mario E Götz; Mersedeh Tohidnezhad; Lars-Ove Brandenburg; Deike Varoga; Oliver Eickelberg; Thomas Herdegen; Christian Trautwein; Kaimin Cha; Yuet Wai Kan; Thomas Pufe
Nrf2 induces interleukin-6 (IL-6) expression via an antioxidant response element within the IL-6 promoter.
The Journal of biological chemistry 2011;286(6):4493-9.
2011: Benedikt J Braun; Alexander Slowik; Stephen L Leib; Ralph Lucius; Deike Varoga; Christoph J Wruck; Sandra Jansen; Rainer Podschun; Thomas Pufe; Lars-Ove Brandenburg
The formyl peptide receptor like-1 and scavenger receptor MARCO are involved in glial cell activation in bacterial meningitis.
Journal of neuroinflammation 2011;8(1):11.
2010: Lars-Ove Brandenburg; Sandra Jansen; Christoph J Wruck; Ralph Lucius; Thomas Pufe
Antimicrobial peptide rCRAMP induced glial cell activation through P2Y receptor signalling pathways.
Molecular immunology 2010;47(10):1905-13.
2010: Lars-Ove Brandenburg; Markus Kipp; Ralph Lucius; Thomas Pufe; Christoph J Wruck
Sulforaphane suppresses LPS-induced inflammation in primary rat microglia.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2010;59(6):443-50.
2010: Lars-Ove Brandenburg; Maximilian Konrad; Christoph J Wruck; Thomas Koch; Ralph Lucius; Thomas Pufe
Functional and physical interactions between formyl-peptide-receptors and scavenger receptor MARCO and their involvement in amyloid beta 1-42-induced signal transduction in glial cells.
Journal of neurochemistry 2010;113(3):749-60.
2010: Fabian Baertling; Maria Kokozidou; Thomas Pufe; Tim clarner; Reinhard Windoffer; Christoph J Wruck; Lars-Ove Brandenburg; Cordian Beyer; Markus Kipp
ADAM12 is expressed by astrocytes during experimental demyelination.
Brain research 2010;1326():1-14.
2009: Lars-Ove Brandenburg; Deike Varoga; Nicoletta Nicolaeva; Stephen Leib; Rainer Podschun; Christoph J Wruck; Henrik Wilms; Ralph Lucius; Thomas Pufe
Expression and regulation of antimicrobial peptide rCRAMP after bacterial infection in primary rat meningeal cells.
Journal of neuroimmunology 2009;217(1-2):55-64.
2009: Lars-Ove Brandenburg; Ralph Lucius; Azami Tameh Abolfazl; Markus Kipp; Christoph J Wruck; Thomas Koch; Cordian Beyer; Thomas Pufe
Internalization and signal transduction of PrP(106-126) in neuronal cells.
Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft 2009;191(5):459-68.
2009: Lars-Ove Brandenburg; Svenja Seyferth; Christoph J Wruck; Thomas Koch; Philip Rosenstiel; Ralph Lucius; Thomas Pufe
Involvement of Phospholipase D 1 and 2 in the subcellular localization and activity of formyl-peptide-receptors in the human colonic cell line HT29.
Molecular membrane biology 2009;26(5):371-83.
2009: Christoph J Wruck; Berthold Huppertz; Patrick Bose; Lars-Ove Brandenburg; Thomas Pufe; Mamed Kadyrov
Role of a fetal defence mechanism against oxidative stress in the aetiology of preeclampsia.
Histopathology 2009;55(1):102-6.
2009: Deike Varoga; E Klostermeier; Friedrich P Paulsen; Christoph J Wruck; S Lippross; L O Brandenburg; Mersedeh Tohidnezhad; A Seekamp; Bernhard Tillmann; Thomas Pufe
The antimicrobial peptide HBD-2 and the Toll-like receptors-2 and -4 are induced in synovial membranes in case of septic arthritis.
Virchows Archiv : an international journal of pathology 2009;454(6):685-94.
2009: Deike Varoga; Christoph J Wruck; Mersedeh Tohidnezhad; L Brandenburg; Friedrich P Paulsen; Rolf Mentlein; A Seekamp; Lutz Besch; Thomas Pufe
Osteoblasts participate in the innate immunity of the bone by producing human beta defensin-3.
Histochemistry and cell biology 2009;131(2):207-18.
2008: Lars-Ove Brandenburg; Deike Varoga; Nicoletta Nicolaeva; Stephen Leib; Henrik Wilms; Rainer Podschun; Christoph J Wruck; Jens Schröder; Thomas Pufe; Ralph Lucius
Role of glial cells in the functional expression of LL-37/rat cathelin-related antimicrobial peptide in meningitis.
Journal of neuropathology and experimental neurology 2008;67(11):1041-54.
2008: L-O Brandenburg; M Konrad; Christoph J Wruck; T Koch; T Pufe; Ralph Lucius
Involvement of formyl-peptide-receptor-like-1 and phospholipase D in the internalization and signal transduction of amyloid beta 1-42 in glial cells.
Neuroscience 2008;156(2):266-76.
2008: Christoph J Wruck; Mario E Götz; Thomas Herdegen; Deike Varoga; Lars-Ove Brandenburg; Thomas Pufe
Kavalactones protect neural cells against amyloid beta peptide-induced neurotoxicity via extracellular signal-regulated kinase 1/2-dependent nuclear factor erythroid 2-related factor 2 activation.
Molecular pharmacology 2008;73(6):1785-95.
2008: Thomas Pufe; Wolf Petersen; Fred Fändrich; Deike Varoga; Christoph J Wruck; Rolf Mentlein; Andreas Helfenstein; Daniela Hoseas; Stefanie Dressel; Bernhard Tillmann; Maren Ruhnke
Programmable cells of monocytic origin (PCMO): a source of peripheral blood stem cells that generate collagen type II-producing chondrocytes.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2008;26(3):304-13.
2007: Thomas Pufe; Horst Claassen; Katharina E Scholz-Ahrens; Deike Varoga; Wolf Drescher; A T M Franke; Christoph J Wruck; Wolf Petersen; Christian Cellarius; Jürgen Schrezenmeir; Claus Glüer
Influence of estradiol on vascular endothelial growth factor expression in bone: a study in Göttingen miniature pigs and human osteoblasts.
Calcified tissue international 2007;80(3):184-91.
2007: Sierk Haenisch; U Zimmermann; Eike Dazert; Christoph J Wruck; Peter Dazert; Werner Siegmund; S Siegmund; Heyo K Kroemer; Rolf Warzok; Ingolf Cascorbi
Influence of polymorphisms of ABCB1 and ABCC2 on mRNA and protein expression in normal and cancerous kidney cortex.
The pharmacogenomics journal 2007;7(1):56-65.
2007: Christoph J Wruck; Malte Claussen; G Fuhrmann; L Römer; A Schulz; Thomas Pufe; Vicki Waetzig; M Peipp; T Herdegen; M E Götz
Luteolin protects rat PC12 and C6 cells against MPP+ induced toxicity via an ERK dependent Keap1-Nrf2-ARE pathway.
Journal of neural transmission. Supplementum 2007;(72):57-67.
2006: Deike Varoga; Friedrich Paulsen; Rolf Mentlein; Jakob Fay; Bodo Kurz; R Schütz; Christoph J Wruck; Mary B Goldring; Thomas Pufe
TLR-2-mediated induction of vascular endothelial growth factor (VEGF) in cartilage in septic joint disease.
The Journal of pathology 2006;210(3):315-24.
2006: Jakob Fay; Deike Varoga; Christoph J Wruck; Bodo Kurz; Mary B Goldring; Thomas Pufe
Reactive oxygen species induce expression of vascular endothelial growth factor in chondrocytes and human articular cartilage explants.
Arthritis research & therapy 2006;8(6):R189.
2005: Christoph J Wruck; Heiko Funke-Kaiser; Thomas Pufe; heike kusserow; Mario Menk; Jan H Schefe; Marie L Kruse; Monika Stoll; Thomas Unger
Regulation of transport of the angiotensin AT2 receptor by a novel membrane-associated Golgi protein.
Arteriosclerosis, thrombosis, and vascular biology 2005;25(1):57-64.