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Bill Wu

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Bei Liu; Crystal Morales; Matthew Staron; Shaoli Sun; Stephen Tomlinson; Bill X Wu; Dianqing Wu; Craig E Crosson; Feng Hong; Ingyu Kim; Zihai Li
Essential roles of grp94 in gut homeostasis via chaperoning canonical Wnt pathway.
Ashley J Snider; Jonathan A Sticca; Bill X Wu; Yusuf A Hannun; Russell W Jenkins; Toshihiko Kawamori; Lina M Obeid
Loss of neutral ceramidase increases inflammation in a mouse model of inflammatory bowel disease.
Bill X Wu; Nana Bartke; Christopher J Clarke; Nabil Matmati; David Montefusco; Yusuf A Hannun
Identification of novel anionic phospholipid binding domains in neutral sphingomyelinase 2 with selective binding preference.

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All Publications

2013: Bei Liu; Crystal Morales; Matthew Staron; Shaoli Sun; Stephen Tomlinson; Bill X Wu; Dianqing Wu; Craig E Crosson; Feng Hong; Ingyu Kim; Zihai Li
Essential roles of grp94 in gut homeostasis via chaperoning canonical Wnt pathway.
Proceedings of the National Academy of Sciences of the United States of America 2013;110(17):6877-82.
2012: Ashley J Snider; Jonathan A Sticca; Bill X Wu; Yusuf A Hannun; Russell W Jenkins; Toshihiko Kawamori; Lina M Obeid
Loss of neutral ceramidase increases inflammation in a mouse model of inflammatory bowel disease.
Prostaglandins & other lipid mediators 2012;99(3-4):124-30.
2011: Bill X Wu; Nana Bartke; Christopher J Clarke; Nabil Matmati; David Montefusco; Yusuf A Hannun
Identification of novel anionic phospholipid binding domains in neutral sphingomyelinase 2 with selective binding preference.
The Journal of biological chemistry 2011;286(25):22362-71.
2011: Russell W Jenkins; Christopher J Clarke; Daniel Canals; Ashley J Snider; Christopher R Gault; Linda Heffernan-Stroud; Bill X Wu; Fabio Simbari; Patrick Roddy; Kazuyuki Kitatani; Lina M Obeid; Yusuf A Hannun
Regulation of CC ligand 5/RANTES by acid sphingomyelinase and acid ceramidase.
The Journal of biological chemistry 2011;286(15):13292-303.
2011: Christopher J Clarke; Bill X Wu; Yusuf A Hannun
The neutral sphingomyelinase family: identifying biochemical connections.
Advances in enzyme regulation 2011;51(1):51-8.
2010: Bill X Wu; Christopher J Clarke; Yusuf A Hannun
Mammalian neutral sphingomyelinases: regulation and roles in cell signaling responses.
Neuromolecular medicine 2010;12(4):320-30.
2010: Yoshikazu Uchida; Evi Houben; Kyungho Park; Sounthala Douangpanya; Yong-Moon Lee; Bill X Wu; Yusuf A Hannun; Norman S Radin; Peter M Elias; Walter M Holleran
Hydrolytic pathway protects against ceramide-induced apoptosis in keratinocytes exposed to UVB.
The Journal of investigative dermatology 2010;130(10):2472-80.
2010: Bill X Wu; Vinodh Rajagopalan; Patrick Roddy; Christopher J Clarke; Yusuf A Hannun
Identification and characterization of murine mitochondria-associated neutral sphingomyelinase (MA-nSMase), the mammalian sphingomyelin phosphodiesterase 5.
The Journal of biological chemistry 2010;285(23):17993-8002.
2009: Hong Yu; Youssef H Zeidan; Bill X Wu; Russell W Jenkins; Terence R Flotte; Yusuf A Hannun; Isabel Virella-Lowell
Defective acid sphingomyelinase pathway with Pseudomonas aeruginosa infection in cystic fibrosis.
American journal of respiratory cell and molecular biology 2009;41(3):367-75.
2009: Bill X Wu; Youssef H Zeidan; Yusuf A Hannun
Downregulation of neutral ceramidase by gemcitabine: Implications for cell cycle regulation.
Biochimica et biophysica acta 2009;1791(8):730-9.
2008: L-Ruth Montes; David J López; Jesús Sot; Luis A Bagatolli; Martin J Stonehouse; Michael Vasil; Bill X Wu; Yusuf A Hannun; Félix M Goñi; Alicia Alonso
Ceramide-enriched membrane domains in red blood cells and the mechanism of sphingomyelinase-induced hot-cold hemolysis.
Biochemistry 2008;47(43):11222-30.
2008: Mickael O Pata; Bill X Wu; Jacek Bielawski; Tou-Cheu Xiong; Yusuf A Hannun; Carl K-Y Ng
Molecular cloning and characterization of OsCDase, a ceramidase enzyme from rice.
The Plant journal : for cell and molecular biology 2008;55(6):1000-9.
2008: Samar M Hammad; Heather G Crellin; Bill X Wu; Jessica Melton; Viviana Anelli; Lina M Obeid
Dual and distinct roles for sphingosine kinase 1 and sphingosine 1 phosphate in the response to inflammatory stimuli in RAW macrophages.
Prostaglandins & other lipid mediators 2008;85(3-4):107-14.
2008: Youssef H Zeidan; Bill X Wu; Russell W Jenkins; Lina M Obeid; Yusuf A Hannun
A novel role for protein kinase Cdelta-mediated phosphorylation of acid sphingomyelinase in UV light-induced mitochondrial injury.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008;22(1):183-93.
2007: Bill X Wu; Christopher F Snook; Motohiro Tani; Erika-Elisabeth Bullesbach; Yusuf A Hannun
Large-scale purification and characterization of recombinant Pseudomonas ceramidase: regulation by calcium.
Journal of lipid research 2007;48(3):600-8.
2006: Jie Fan; Bill X Wu; Tadeusz Sarna; Baerbel Rohrer; T Michael Redmond; Rosalie K Crouch
9-cis Retinal increased in retina of RPE65 knockout mice with decrease in coat pigmentation.
Photochemistry and photobiology 2006;82(6):1461-7.
2006: Mazen El Alwani; Bill X Wu; Lina M Obeid; Yusuf A Hannun
Bioactive sphingolipids in the modulation of the inflammatory response.
Pharmacology & therapeutics 2006;112(1):171-83.
2006: Sehamuddin Galadari; Bill X Wu; Cungui Mao; Patrick Roddy; Samer El Bawab; Yusuf A Hannun
Identification of a novel amidase motif in neutral ceramidase.
The Biochemical journal 2006;393(Pt 3):687-95.
2006: Bill X Wu; Alix G Darden; Martin Laser; Yan Li; Craig E Crosson; E Starr Hazard; Jian-Xing Ma
The rat Apg3p/Aut1p homolog is upregulated by ischemic preconditioning in the retina.
Molecular vision 2006;12():1292-302.
2005: Gennadiy Moiseyev; Ying Chen; Yusuke Takahashi; Bill X Wu; Jian-Xing Ma
RPE65 is the isomerohydrolase in the retinoid visual cycle.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(35):12413-8.
2004: Bill X Wu; Gennadiy Moiseyev; Ying Chen; Baerbel Rohrer; Rosalie K Crouch; Jian-Xing Ma
Identification of RDH10, an All-trans Retinol Dehydrogenase, in Retinal Muller Cells.
Investigative ophthalmology & visual science 2004;45(11):3857-62.
2003: Yumei Chen; Gennadiy Moiseyev; Bill X Wu; Jian-Xing Ma; Rosalie K Crouch
Visual cycle retinoid processing proteins are present in HEK293S cells.
Vision research 2003;43(28):3037-44.
2003: Alix G Darden; Bill X Wu; Sergey L Znoiko; E Starr Hazard; Masahiro Kono; Rosalie K Crouch; Jian-Xing Ma
A novel Xenopus SWS2, P434 visual pigment: structure, cellular location, and spectral analyses.
Molecular vision 2003;9():191-9.
2002: Bill X Wu; Ying Chen; Yumei Chen; Jie Fan; Baerbel Rohrer; Rosalie K Crouch; Jian-Xing Ma
Cloning and characterization of a novel all-trans retinol short-chain dehydrogenase/reductase from the RPE.
Investigative ophthalmology & visual science 2002;43(11):3365-72.