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Chuanyue Wu

Research Profile

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TOP 3
Vasiliki Gkretsi; Vassilis Papanikolaou; Chuanyue Wu; Lefteris C Zacharia; Evangelos Athanassiou; Aspasia Tsezou
Mitogen-inducible Gene-2 (MIG2) and Migfilin Expression Is Reduced in Samples of Human Breast Cancer.
Yunwei Ou; Lijia Dong; Jing Fan; Liying Ma; Li Ma; Ling Ma; Chuanyue Wu; Chunjiang Yu; Qimin Zhan; Zitong Zhao; Wei Zhou; Yongmei Song
Migfilin protein promotes migration and invasion in human glioma through epidermal growth factor receptor-mediated phospholipase C-γ and STAT3 protein signaling pathways.
Ben Davidson; Arild Holth; Mai T P Nguyen; Claes G Tropé; Chuanyue Wu
Migfilin, α-parvin and β-parvin are differentially expressed in ovarian serous carcinoma effusions, primary tumors and solid metastases.

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All Publications

2013: Vasiliki Gkretsi; Vassilis Papanikolaou; Chuanyue Wu; Lefteris C Zacharia; Evangelos Athanassiou; Aspasia Tsezou
Mitogen-inducible Gene-2 (MIG2) and Migfilin Expression Is Reduced in Samples of Human Breast Cancer.
Anticancer research 2013;33(5):1977-81.
2013: Yunwei Ou; Lijia Dong; Jing Fan; Liying Ma; Li Ma; Ling Ma; Chuanyue Wu; Chunjiang Yu; Qimin Zhan; Zitong Zhao; Wei Zhou; Yongmei Song
Migfilin protein promotes migration and invasion in human glioma through epidermal growth factor receptor-mediated phospholipase C-γ and STAT3 protein signaling pathways.
The Journal of biological chemistry 2013;288(15):10948.
2013: Ben Davidson; Arild Holth; Mai T P Nguyen; Claes G Tropé; Chuanyue Wu
Migfilin, α-parvin and β-parvin are differentially expressed in ovarian serous carcinoma effusions, primary tumors and solid metastases.
Gynecologic oncology 2013;128(2):364-70.
2013: Vasiliki Gkretsi; Konstantinos N Malizos; Vassilis Papanikolaou; Ioanna Papathanasiou; Stephanie Dubos; Nikolina Giotopoulou; Vaia Valiakou; Chuanyue Wu; Aspasia Tsezou
Migfilin's elimination from osteoarthritic chondrocytes further promotes the osteoarthritic phenotype via β-catenin upregulation.
Biochemical and biophysical research communications 2013;430(2):494-9.
2012: Jun Qin; Chuanyue Wu
ILK: a pseudokinase in the center stage of cell-matrix adhesion and signaling.
Current opinion in cell biology 2012;24(5):607-13.
2012: Yunwei Ou; Lijia Dong; Jing Fan; Ling Ma; Liying Ma; Li Ma; Chuanyue Wu; Chunjiang Yu; Qimin Zhan; Zitong Zhao; Wei Zhou; Yongmei Song
Migfilin protein promotes migration and invasion in human glioma through epidermal growth factor receptor-mediated phospholipase C-γ and STAT3 protein signaling pathways.
The Journal of biological chemistry 2012;287(39):32394-405.
2012: Ling Lin; Chuanyue Wu; Kebin Hu
Tissue plasminogen activator activates NF-κB through a pathway involving annexin A2/CD11b and integrin-linked kinase.
Journal of the American Society of Nephrology : JASN 2012;23(8):1329-38.
2012: Guozhi Xiao; Shengyong Yang; Shibing Yu; Huiling Cao; Di Chen; Ju Chen; Ka Chen; Hongqiang Cheng; Hee-Jeong Im; Hongli Jiao; Yizeng Tu; Chuanyue Wu
Critical role of filamin-binding LIM protein 1 (FBLP-1)/migfilin in regulation of bone remodeling.
The Journal of biological chemistry 2012;287(25):21450-60.
2012: Huan He; Yi Li; Hongyan Chen; Fang Ding; Aiping Luo; Chuanyue Wu; Zhihua Liu
Migfilin regulates esophageal cancer cell motility through promoting GSK-3β-mediated degradation of β-catenin.
Molecular cancer research : MCR 2012;10(3):273-81.
2011: Zhongmin Liu; Maria Pia Rastaldi; Robert Tisherman; Yizeng Tu; James H Wang; Simone M Blattner; Matthias Kretzler; Chuanyue Wu
Alpha-actinin-4 and CLP36 protein deficiencies contribute to podocyte defects in multiple human glomerulopathies.
The Journal of biological chemistry 2011;286(35):30795-805.
2011: Hong Qu; Yizeng Tu; Xiaohua Shi; Hannu Larjava; Moin A Saleem; Sanford J Shattil; Koichi Fukuda; Jun Qin; Matthias Kretzler; Chuanyue Wu
Kindlin-2 regulates podocyte adhesion and fibronectin matrix deposition through interactions with phosphoinositides and integrins.
Journal of cell science 2011;124(Pt 6):879-91.
2011: Shashikiran Donthamsetty; Vishakha S Bhave; Corrine S Kliment; William C Bowen; Wendy M Mars; Aaron W Bell; Rachel E Stewart; Anne Orr; Chuanyue Wu; George K Michalopoulos
Excessive hepatomegaly of mice with hepatocyte-targeted elimination of integrin linked kinase following treatment with 1,4-bis [2-(3,5-dichaloropyridyloxy)] benzene.
Hepatology (Baltimore, Md.) 2011;53(2):587-95.
2011: Y Yuan; Hiep Phuc Dong; D A Nymoen; Jahn M Nesland; Chuanyue Wu; Ben Davidson
PINCH-2 expression in cancers involving serosal effusions using quantitative PCR.
Cytopathology : official journal of the British Society for Clinical Cytology 2011;22(1):22-9.
2011: Laura Bavagnoli; Ilaria Capua; William G Dundon; Anna Garbelli; Adelaide Milani; Stefania Paolucci; Geetha Parakkal; Yizeng Tu; Romain Volmer; Chuanyue Wu; Bianca Zecchin; Fausto Baldanti; Giovanni Maga
The PDZ-ligand and Src-homology type 3 domains of epidemic avian influenza virus NS1 protein modulate human Src kinase activity during viral infection.
PloS one 2011;6(11):e27789.
2011: Shashikiran Donthamsetty; Wendy M Mars; Anne Orr; Chuanyue Wu; George K Michalopoulos
Protection against Fas-induced fulminant hepatic failure in liver specific integrin linked kinase knockout mice.
Comparative hepatology 2011;10():11.
2011: Dan Wang; Yingjian Li; Chuanyue Wu; Youhua Liu
PINCH1 is transcriptional regulator in podocytes that interacts with WT1 and represses podocalyxin expression.
PloS one 2011;6(2):e17048.
2010: Kamila Bledzka; Katarzyna Bialkowska; Huiqin Nie; Jun Qin; Tatiana V Byzova; Chuanyue Wu; Edward F Plow; Yan-Qing Ma
Tyrosine phosphorylation of integrin beta3 regulates kindlin-2 binding and integrin activation.
The Journal of biological chemistry 2010;285(40):30370-4.
2010: Young Sun Kang; Yingjian Li; Chunsun Dai; Lawrence P Kiss; Chuanyue Wu; Youhua Liu
Inhibition of integrin-linked kinase blocks podocyte epithelial-mesenchymal transition and ameliorates proteinuria.
Kidney international 2010;78(4):363-73.
2010: Yu-Chen Han; Yan Ping Yu; Joel Nelson; Chuanyue Wu; Hui Wang; George K Michalopoulos; Jian-Hua Luo
Interaction of integrin-linked kinase and miniature chromosome maintenance 7-mediating integrin {alpha}7 induced cell growth suppression.
Cancer research 2010;70(11):4375-84.
2010: Gethin Rh Owen; Lari Häkkinen; Chuanyue Wu; Hannu Larjava
A reproducible technique for specific labeling of antigens using preformed fluorescent molecular IgG-F(ab')2 complexes from primary antibodies of the same species.
Microscopy research and technique 2010;73(6):623-30.
2010: Hanshuang Shao; Chuanyue Wu; Alan Wells
Phosphorylation of alpha-actinin 4 upon epidermal growth factor exposure regulates its interaction with actin.
The Journal of biological chemistry 2010;285(4):2591-600.
2010: Priyangi M Perera; Ewa Wypasek; Shashi Madhavan; Birgit Rath-Deschner; Jie Liu; Jin Nam; Bjoern Rath; Yan Huang; James Deschner; Nicholas Piesco; Chuanyue Wu; Sudha Agarwal
Mechanical signals control SOX-9, VEGF, and c-Myc expression and cell proliferation during inflammation via integrin-linked kinase, B-Raf, and ERK1/2-dependent signaling in articular chondrocytes.
Arthritis research & therapy 2010;12(3):R106.
2009: Koichi Fukuda; Sudhiranjan Gupta; Ka Chen; Chuanyue Wu; Jun Qin
The pseudoactive site of ILK is essential for its binding to alpha-Parvin and localization to focal adhesions.
Molecular cell 2009;36(5):819-30.
2009: Jianping Zhao; Yongjun Zhang; Sujay Subbayya Ithychanda; Yizeng Tu; Ka Chen; Jun Qin; Chuanyue Wu
Migfilin interacts with Src and contributes to cell-matrix adhesion-mediated survival signaling.
The Journal of biological chemistry 2009;284(49):34308-20.
2009: Yuan Yuan; Dag André Nymoen; Helene Tuft Stavnes; Anne Katrine Rosnes; Ola Bjørang; Chuanyue Wu; Jahn M Nesland; Ben Davidson
Tenascin-X is a novel diagnostic marker of malignant mesothelioma.
The American journal of surgical pathology 2009;33(11):1673-82.
2009: Giorgio Petricca; Mari Leppilampi; Guoqiao Jiang; Gethin R Owen; Colin Wiebe; Yizeng Tu; Leeni Koivisto; Lari Häkkinen; Chuanyue Wu; Hannu Larjava
Localization and potential function of kindlin-1 in periodontal tissues.
European journal of oral sciences 2009;117(5):518-27.
2009: Udayan M Apte; Vasiliki Gkretsi; William C Bowen; Wendy M Mars; Jian-Hua Luo; Shashikiran Donthamsetty; Ann Orr; Satdarshan Pal S. Monga; Chuanyue Wu; George K Michalopoulos
Enhanced liver regeneration following changes induced by hepatocyte-specific genetic ablation of integrin-linked kinase.
Hepatology (Baltimore, Md.) 2009;50(3):844-51.
2009: Xingqun Liang; Yunfu Sun; Maoqing Ye; Maria C Scimia; Hongqiang Cheng; Jody Martin; Gang Wang; Ann Rearden; Chuanyue Wu; Kirk L Peterson; Henry C Powell; Sylvia M Evans; Ju Chen
Targeted ablation of PINCH1 and PINCH2 from murine myocardium results in dilated cardiomyopathy and early postnatal lethality.
Circulation 2009;120(7):568-76.
2009: Wen Yue; Quanhong Sun; Rodney Landreneau; Chuanyue Wu; Jill M Siegfried; Jian Yu; Lin Zhang
Fibulin-5 suppresses lung cancer invasion by inhibiting matrix metalloproteinase-7 expression.
Cancer research 2009;69(15):6339-46.
2009: Yongjun Zhang; Yizeng Tu; Jianping Zhao; Ka Chen; Chuanyue Wu
Reversion-induced LIM interaction with Src reveals a novel Src inactivation cycle.
The Journal of cell biology 2009;184(6):785-92.
2009: Nasreen Akhtar; Rebecca Marlow; Elise Lambert; Franziska Schatzmann; Emma T Lowe; Julia Cheung; Elad Katz; Weiping Li; Chuanyue Wu; Shoukat Dedhar; Matthew J Naylor; Charles H Streuli
Molecular dissection of integrin signalling proteins in the control of mammary epithelial development and differentiation.
Development (Cambridge, England) 2009;136(6):1019-27.
2009: Yanwu Yang; Xiaoxia Wang; Cheryl A Hawkins; Kan Chen; Julia Vaynberg; Xian Mao; Yizeng Tu; Xiaobing Zuo; Jinbu Wang; Yun-Xing Wang; Chuanyue Wu; Nico Tjandra; Jun Qin
Structural basis of focal adhesion localization of LIM-only adaptor PINCH by integrin-linked kinase.
The Journal of biological chemistry 2009;284(9):5836-44.
2009: Sujay Subbayya Ithychanda; Mitali Das; Yan-Qing Ma; Keyang Ding; Xiaoxia Wang; Sudhiranjan Gupta; Chuanyue Wu; Edward F Plow; Jun Qin
Migfilin, a molecular switch in regulation of integrin activation.
The Journal of biological chemistry 2009;284(7):4713-22.
2008: Hannu Larjava; Edward F Plow; Chuanyue Wu
Kindlins: essential regulators of integrin signalling and cell-matrix adhesion.
EMBO reports 2008;9(12):1203-8.
2008: Vasiliki Gkretsi; Udayan Apte; Wendy M Mars; William C Bowen; Jian-Hua Luo; Yu Yang; Yan Ping Yu; Ann Orr; René St-Arnaud; Shoukat Dedhar; Klaus kaestner; Chuanyue Wu; George K Michalopoulos
Liver-specific ablation of integrin-linked kinase in mice results in abnormal histology, enhanced cell proliferation, and hepatomegaly.
Hepatology (Baltimore, Md.) 2008;48(6):1932-41.
2008: Dionysios Papachristou; Vassiliki Gkretsi; Uma N M Rao; Georgios I Papachristou; Odysseas A Papaefthymiou; Efthimia K Basdra; Chuanyue Wu; Athanasios G Papavassiliou
Expression of integrin-linked kinase and its binding partners in chondrosarcoma: association with prognostic significance.
European journal of cancer (Oxford, England : 1990) 2008;44(16):2518-25.
2008: Z Tang; R Du; S Jiang; Chuanyue Wu; D S Barkauskas; J Richey; J Molter; M Lam; Chris A Flask; Stanton L Gerson; Afshin Dowlati; L Liu; Zhenghong Lee; Balazs Halmos; Y Wang; Jeffrey A Kern; Patrick C Ma
Dual MET-EGFR combinatorial inhibition against T790M-EGFR-mediated erlotinib-resistant lung cancer.
British journal of cancer 2008;99(6):911-22.
2008: Xiaoxia Wang; Koichi Fukuda; In-Ja Byeon; Algirdas Velyvis; Chuanyue Wu; Angela Gronenborn; Jun Qin
The structure of alpha-parvin CH2-paxillin LD1 complex reveals a novel modular recognition for focal adhesion assembly.
The Journal of biological chemistry 2008;283(30):21113-9.
2008: Xiaohua Shi; Hong Qu; Matthias Kretzler; Chuanyue Wu
Roles of PINCH-2 in regulation of glomerular cell shape change and fibronectin matrix deposition.
American journal of physiology. Renal physiology 2008;295(1):F253-63.
2008: Yan-Qing Ma; Jun Qin; Chuanyue Wu; Edward F Plow
Kindlin-2 (Mig-2): a co-activator of beta3 integrins.
The Journal of cell biology 2008;181(3):439-46.
2008: Xiaohua Shi; Chuanyue Wu
A suppressive role of mitogen inducible gene-2 in mesenchymal cancer cell invasion.
Molecular cancer research : MCR 2008;6(5):715-24.
2008: Colin B Wiebe; Giorgio Petricca; Lari Häkkinen; Guoqiao Jiang; Chuanyue Wu; Hannu Larjava
Kindler syndrome and periodontal disease: review of the literature and a 12-year follow-up case.
Journal of periodontology 2008;79(5):961-6.
2008: Lam Helmick; Adriana Antúnez de Mayolo; Ying Zhang; Chao-Min Cheng; simon simon watkins; Chuanyue Wu; Philip R LeDuc
Spatiotemporal response of living cell structures in Dictyostelium discoideum with semiconductor quantum dots.
Nano letters 2008;8(5):1303-8.
2008: Ka Chen; Yizeng Tu; Yongjun Zhang; Harry C Blair; Lin Zhang; Chuanyue Wu
PINCH-1 regulates the ERK-Bim pathway and contributes to apoptosis resistance in cancer cells.
The Journal of biological chemistry 2008;283(5):2508-17.
2007: Kebin Hu; Chuanyue Wu; Wendy M Mars; Youhua Liu
Tissue-type plasminogen activator promotes murine myofibroblast activation through LDL receptor-related protein 1-mediated integrin signaling.
The Journal of clinical investigation 2007;117(12):3821-32.
2007: Wenwu Zhang; Yidi Wu; Chuanyue Wu; Susan J Gunst
Integrin-linked kinase regulates N-WASp-mediated actin polymerization and tension development in tracheal smooth muscle.
The Journal of biological chemistry 2007;282(47):34568-80.
2007: Dionysios Papachristou; Vasiliki Gkretsi; Yizeng Tu; X Shi; Ka Chen; H Larjava; Uma N M Rao; Chuanyue Wu
Increased cytoplasmic level of migfilin is associated with higher grades of human leiomyosarcoma.
Histopathology 2007;51(4):499-508.
2007: Yingjian Li; Chunsun Dai; Chuanyue Wu; Youhua Liu
PINCH-1 promotes tubular epithelial-to-mesenchymal transition by interacting with integrin-linked kinase.
Journal of the American Society of Nephrology : JASN 2007;18(9):2534-43.
2007: Sung Min Kim; Nari Kim; Seoul Lee; Do Kyung Kim; Yu Min Lee; Seon Ho Ahn; Ju Hung Song; Bong Kyu Choi; Chuanyue Wu; Kyu Yong Jung
TGF-beta1-induced PINCH-1-ILK-alpha-parvin complex formation regulates mesangial cell proliferation and hypertrophy.
Experimental & molecular medicine 2007;39(4):514-23.
2007: Xiaohua Shi; Yan-Qing Ma; Yizeng Tu; Ka Chen; Shan Wu; Koichi Fukuda; Jun Qin; Edward F Plow; Chuanyue Wu
The MIG-2/integrin interaction strengthens cell-matrix adhesion and modulates cell motility.
The Journal of biological chemistry 2007;282(28):20455-66.
2007: Baoguo Ren; Yan Ping Yu; Chien Cheng (George) Tseng; Chuanyue Wu; Ka Chen; Uma N M Rao; Joel Nelson; George K Michalopoulos; Jian-Hua Luo
Analysis of integrin alpha7 mutations in prostate cancer, liver cancer, glioblastoma multiforme, and leiomyosarcoma.
Journal of the National Cancer Institute 2007;99(11):868-80.
2007: Yingxiao Wang; Joann Chang; Kuang-Den Chen; Song Li; Julie Yi-Shuan Li; Chuanyue Wu; Shu Chien
Selective adapter recruitment and differential signaling networks by VEGF vs. shear stress.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(21):8875-9.
2007: Vasiliki Gkretsi; Wendy M Mars; William C Bowen; Lindsay Barua; Yu Yang; Lida Guo; René St-Arnaud; Shoukat Dedhar; Chuanyue Wu; George K Michalopoulos
Loss of integrin linked kinase from mouse hepatocytes in vitro and in vivo results in apoptosis and hepatitis.
Hepatology (Baltimore, Md.) 2007;45(4):1025-34.
2007: Vasiliki Gkretsi; William C Bowen; Yu Yang; Chuanyue Wu; George K Michalopoulos
Integrin-linked kinase is involved in matrix-induced hepatocyte differentiation.
Biochemical and biophysical research communications 2007;353(3):638-43.
2007: Andrew R Samuelsson; Richard Belvindrah; Chuanyue Wu; Uli Müller; Willi Halfter
Beta1-integrin signaling is essential for lens fiber survival.
Gene regulation and systems biology 2007;1():177-89.
2007: Chuanyue Wu
Focal adhesion: a focal point in current cell biology and molecular medicine.
Cell adhesion & migration 2007;1(1):13-8.
2007: Kyu Yong Jung; Ka Chen; Matthias Kretzler; Chuanyue Wu
TGF-beta1 regulates the PINCH-1-integrin-linked kinase-alpha-parvin complex in glomerular cells.
Journal of the American Society of Nephrology : JASN 2007;18(1):66-73.
2006: Xiangmei Chen; Zhihui Li; Zhe Feng; Jianzhong Wang; Chun Ouyang; Weiping Liu; Bo Fu; Guangyan Cai; Chuanyue Wu; Ribao Wei; Di Wu; Quan Hong
Integrin-linked kinase induces both senescence-associated alterations and extracellular fibronectin assembly in aging cardiac fibroblasts.
The journals of gerontology. Series A, Biological sciences and medical sciences 2006;61(12):1232-45.
2006: Joseph M Gozgit; Brian T Pentecost; Sharon Marconi; Christopher N Otis; Chuanyue Wu; Kathleen F Arcaro
Use of an aggressive MCF-7 cell line variant, TMX2-28, to study cell invasion in breast cancer.
Molecular cancer research : MCR 2006;4(12):905-13.
2006: Richard Belvindrah; Perihan Nalbant; Sheng Ding; Chuanyue Wu; Gary M Bokoch; Ulrich Müller
Integrin-linked kinase regulates Bergmann glial differentiation during cerebellar development.
Molecular and cellular neurosciences 2006;33(2):109-25.
2006: Chunsun Dai; Donna B Stolz; Sheldon Bastacky; René St-Arnaud; Chuanyue Wu; Shoukat Dedhar; Youhua Liu
Essential role of integrin-linked kinase in podocyte biology: Bridging the integrin and slit diaphragm signaling.
Journal of the American Society of Nephrology : JASN 2006;17(8):2164-75.
2006: Yongjun Zhang; Yizeng Tu; Vasiliki Gkretsi; Chuanyue Wu
Migfilin interacts with vasodilator-stimulated phosphoprotein (VASP) and regulates VASP localization to cell-matrix adhesions and migration.
The Journal of biological chemistry 2006;281(18):12397-407.
2006: Jorge L Sepulveda; Chuanyue Wu
The parvins.
Cellular and molecular life sciences : CMLS 2006;63(1):25-35.
2005: Beatrice B Yaroslavskiy; Yongjun Zhang; Sara E Kalla; Verónica García Palacios; Allison C Sharrow; Yanan Li; Mone Zaidi; Chuanyue Wu; Harry C Blair
NO-dependent osteoclast motility: reliance on cGMP-dependent protein kinase I and VASP.
Journal of cell science 2005;118(Pt 23):5479-87.
2005: Hua Chen; Xueyin N Huang; Wen Yan; Ka Chen; Lida Guo; Lekha Tummalapali; Shoukat Dedhar; René St-Arnaud; Chuanyue Wu; Jorge L Sepulveda
Role of the integrin-linked kinase/PINCH1/alpha-parvin complex in cardiac myocyte hypertrophy.
Laboratory investigation; a journal of technical methods and pathology 2005;85(11):1342-56.
2005: Chuanyue Wu
PINCH, N(i)ck and the ILK: network wiring at cell-matrix adhesions.
Trends in cell biology 2005;15(9):460-6.
2005: Zhen Xu; Tomohiko Fukuda; You Li; Xiliang Zha; Jun Qin; Chuanyue Wu
Molecular dissection of PINCH-1 reveals a mechanism of coupling and uncoupling of cell shape modulation and survival.
The Journal of biological chemistry 2005;280(30):27631-7.
2005: Yanqiang Yang; Lida Guo; Simone M Blattner; Peter Mundel; Matthias Kretzler; Chuanyue Wu
Formation and phosphorylation of the PINCH-1-integrin linked kinase-alpha-parvin complex are important for regulation of renal glomerular podocyte adhesion, architecture, and survival.
Journal of the American Society of Nephrology : JASN 2005;16(7):1966-76.
2005: Yong Qian; Xiaosong Zhong; Daniel C Flynn; Jenny Z Zheng; Meng Qiao; Chuanyue Wu; Shoukat Dedhar; Xianglin Shi; Bing-Hua Jiang
ILK mediates actin filament rearrangements and cell migration and invasion through PI3K/Akt/Rac1 signaling.
Oncogene 2005;24(19):3154-65.
2005: Julia Vaynberg; Tomohiko Fukuda; Ka Chen; Olga vinogradova; Algirdas Velyvis; Yizeng Tu; Lily Ng; Chuanyue Wu; Jun Qin
Structure of an ultraweak protein-protein complex and its crucial role in regulation of cell morphology and motility.
Molecular cell 2005;17(4):513-23.
2005: Chuanyue Wu
Migfilin and its binding partners: from cell biology to human diseases.
Journal of cell science 2005;118(Pt 4):659-64.
2005: Vasiliki Gkretsi; Yongjun Zhang; Yizeng Tu; Ka Chen; Donna B Stolz; Yanqiang Yang; simon simon watkins; Chuanyue Wu
Physical and functional association of migfilin with cell-cell adhesions.
Journal of cell science 2005;118(Pt 4):697-710.
2005: Jorge L Sepulveda; Vasiliki Gkretsi; Chuanyue Wu
Assembly and signaling of adhesion complexes.
Current topics in developmental biology 2005;68():183-225.
2005: Dennis F Kucik; Chuanyue Wu
Cell-adhesion assays.
Methods in molecular biology (Clifton, N.J.) 2005;294():43-54.
2004: Zhihui Li; Xiangmei Chen; Yuansheng Xie; Suozhu Shi; Zhe Feng; Bo Fu; Xiaojie Zhang; Guangyan Cai; Chuanyue Wu; Di Wu; Yunjuan Gu
Expression and significance of integrin-linked kinase in cultured cells, normal tissue, and diseased tissue of aging rat kidneys.
The journals of gerontology. Series A, Biological sciences and medical sciences 2004;59(10):984-96.
2004: Yongjun Zhang; Ka Chen; Yizeng Tu; Chuanyue Wu
Distinct roles of two structurally closely related focal adhesion proteins, alpha-parvins and beta-parvins, in regulation of cell morphology and survival.
The Journal of biological chemistry 2004;279(40):41695-705.
2004: Chuanyue Wu
The PINCH-ILK-parvin complexes: assembly, functions and regulation.
Biochimica et biophysica acta 2004;1692(2-3):55-62.
2003: Tomohiko Fukuda; Ka Chen; Xiaohua Shi; Chuanyue Wu
PINCH-1 is an obligate partner of integrin-linked kinase (ILK) functioning in cell shape modulation, motility, and survival.
The Journal of biological chemistry 2003;278(51):51324-33.
2003: Sarah Attwell; Julia Mills; Armelle A Troussard; Chuanyue Wu; Shoukat Dedhar
Integration of cell attachment, cytoskeletal localization, and signaling by integrin-linked kinase (ILK), CH-ILKBP, and the tumor suppressor PTEN.
Molecular biology of the cell 2003;14(12):4813-25.
2003: Ji Li; Hongwei Rao; Dean J Burkin; Stephen J Kaufman; Chuanyue Wu
The muscle integrin binding protein (MIBP) interacts with alpha7beta1 integrin and regulates cell adhesion and laminin matrix deposition.
Developmental biology 2003;261(1):209-19.
2003: Yingjian Li; Junwei Yang; Chunsun Dai; Chuanyue Wu; Youhua Liu
Role for integrin-linked kinase in mediating tubular epithelial to mesenchymal transition and renal interstitial fibrogenesis.
The Journal of clinical investigation 2003;112(4):503-16.
2003: Algirdas Velyvis; Julia Vaynberg; Yanwu Yang; Olga vinogradova; Yongjun Zhang; Chuanyue Wu; Jun Qin
Structural and functional insights into PINCH LIM4 domain-mediated integrin signaling.
Nature structural biology 2003;10(7):558-64.
2003: Yizeng Tu; Shan Wu; Xiaohua Shi; Ka Chen; Chuanyue Wu
Migfilin and Mig-2 link focal adhesions to filamin and the actin cytoskeleton and function in cell shape modulation.
Cell 2003;113(1):37-47.
2003: Tomohiko Fukuda; Lida Guo; Xiaohua Shi; Chuanyue Wu
CH-ILKBP regulates cell survival by facilitating the membrane translocation of protein kinase B/Akt.
The Journal of cell biology 2003;160(7):1001-8.
2002: Yongjun Zhang; Ka Chen; Yizeng Tu; Algirdas Velyvis; Yanwu Yang; Jun Qin; Chuanyue Wu
Assembly of the PINCH-ILK-CH-ILKBP complex precedes and is essential for localization of each component to cell-matrix adhesion sites.
Journal of cell science 2002;115(Pt 24):4777-86.
2002: Yongjun Zhang; Ka Chen; Lida Guo; Chuanyue Wu
Characterization of PINCH-2, a new focal adhesion protein that regulates the PINCH-1-ILK interaction, cell spreading, and migration.
The Journal of biological chemistry 2002;277(41):38328-38.
2002: Lida Guo; Chuanyue Wu
Regulation of fibronectin matrix deposition and cell proliferation by the PINCH-ILK-CH-ILKBP complex.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(10):1298-300.
2002: Silvia Goicoechea; Yizeng Tu; Yun Hua; Ka Chen; Tang-Long Shen; Jun-Lin Guan; Chuanyue Wu
Nck-2 interacts with focal adhesion kinase and modulates cell motility.
The international journal of biochemistry & cell biology 2002;34(7):791-805.
2002: Jareer Kassis; Akihiko Maeda; Norihiro Teramoto; Kenzo Takada; Chuanyue Wu; George Klein; Alan Wells
EBV-expressing AGS gastric carcinoma cell sublines present increased motility and invasiveness.
International journal of cancer. Journal international du cancer 2002;99(5):644-51.
2002: Yongjun Zhang; Lida Guo; Ka Chen; Chuanyue Wu
A critical role of the PINCH-integrin-linked kinase interaction in the regulation of cell shape change and migration.
The Journal of biological chemistry 2002;277(1):318-26.
2001: Chuanyue Wu; Shoukat Dedhar
Integrin-linked kinase (ILK) and its interactors: a new paradigm for the coupling of extracellular matrix to actin cytoskeleton and signaling complexes.
The Journal of cell biology 2001;155(4):505-10.
2001: Chuanyue Wu
ILK interactions.
Journal of cell science 2001;114(Pt 14):2549-50.
2001: Yizeng Tu; Y Huang; Yongjun Zhang; Y Hua; Chuanyue Wu
A new focal adhesion protein that interacts with integrin-linked kinase and regulates cell adhesion and spreading.
The Journal of cell biology 2001;153(3):585-98.
2001: Yizeng Tu; D F Kucik; Chuanyue Wu
Identification and kinetic analysis of the interaction between Nck-2 and DOCK180.
FEBS letters 2001;491(3):193-9.
2001: Algirdas Velyvis; Yanwu Yang; Chuanyue Wu; Jun Qin
Solution structure of the focal adhesion adaptor PINCH LIM1 domain and characterization of its interaction with the integrin-linked kinase ankyrin repeat domain.
The Journal of biological chemistry 2001;276(7):4932-9.
1998: Sanjay Ghosh; Ratan Gachhui; C Crooks; Chuanyue Wu; M P Lisanti; Dennis J Stuehr
Interaction between caveolin-1 and the reductase domain of endothelial nitric-oxide synthase. Consequences for catalysis.
The Journal of biological chemistry 1998;273(35):22267-71.
1998: Brian R Crane; Andrew S Arvai; DK Ghosh; Chuanyue Wu; Elizabeth D Getzoff; Dennis J Stuehr; John A Tainer
Structure of nitric oxide synthase oxygenase dimer with pterin and substrate.
Science (New York, N.Y.) 1998;279(5359):2121-6.
1998: Husam M Abu-Soud; Chuanyue Wu; DK Ghosh; Dennis J Stuehr
Stopped-flow analysis of CO and NO binding to inducible nitric oxide synthase.
Biochemistry 1998;37(11):3777-86.
1998: A Presta; U Siddhanta; Chuanyue Wu; N Sennequier; L Huang; Husam M Abu-Soud; Serpil C Erzurum; Dennis J Stuehr
Comparative functioning of dihydro- and tetrahydropterins in supporting electron transfer, catalysis, and subunit dimerization in inducible nitric oxide synthase.
Biochemistry 1998;37(1):298-310.
1997: Brian R Crane; Andrew S Arvai; Ratan Gachhui; Chuanyue Wu; DK Ghosh; Elizabeth D Getzoff; Dennis J Stuehr; John A Tainer
The structure of nitric oxide synthase oxygenase domain and inhibitor complexes.
Science (New York, N.Y.) 1997;278(5337):425-31.
1997: DK Ghosh; Chuanyue Wu; Eva Pitters; M Moloney; Ernst R Werner; Bernd Mayer; Dennis J Stuehr
Characterization of the inducible nitric oxide synthase oxygenase domain identifies a 49 amino acid segment required for subunit dimerization and tetrahydrobiopterin interaction.
Biochemistry 1997;36(35):10609-19.
1997: Ratan Gachhui; DK Ghosh; Chuanyue Wu; J Parkinson; Brian R Crane; Dennis J Stuehr
Mutagenesis of acidic residues in the oxygenase domain of inducible nitric-oxide synthase identifies a glutamate involved in arginine binding.
Biochemistry 1997;36(17):5097-103.
1996: U Siddhanta; Chuanyue Wu; Husam M Abu-Soud; J Zhang; DK Ghosh; Dennis J Stuehr
Heme iron reduction and catalysis by a nitric oxide synthase heterodimer containing one reductase and two oxygenase domains.
The Journal of biological chemistry 1996;271(13):7309-12.
1996: Paul E Hughes; F Diaz-Gonzalez; L Leong; Chuanyue Wu; J A McDonald; Sanford J Shattil; Mark H Ginsberg
Breaking the integrin hinge. A defined structural constraint regulates integrin signaling.
The Journal of biological chemistry 1996;271(12):6571-4.