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Frederick Wu

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Frederick Y Wu; Eddy Yang; Christopher Willey; Kim Ely; Gaelyn Garrett; Anthony J Cmelak
Refractory lympho-epithelial carcinoma of the nasopharynx: a case report illustrating a protracted clinical course.
Shizhen Emily Wang; Archana Narasanna; Corbin W Whitell; Frederick Y Wu; David B Friedman; Carlos L Arteaga
Convergence of p53 and transforming growth factor beta (TGFbeta) signaling on activating expression of the tumor suppressor gene maspin in mammary epithelial cells.
Shizhen Emily Wang; Incheol Shin; Frederick Y Wu; David B Friedman; Carlos L Arteaga
HER2/Neu (ErbB2) signaling to Rac1-Pak1 is temporally and spatially modulated by transforming growth factor beta.

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All Publications

2009: Frederick Y Wu; Eddy Yang; Christopher Willey; Kim Ely; Gaelyn Garrett; Anthony J Cmelak
Refractory lympho-epithelial carcinoma of the nasopharynx: a case report illustrating a protracted clinical course.
Head & neck oncology 2009;1():18.
2007: Shizhen Emily Wang; Archana Narasanna; Corbin W Whitell; Frederick Y Wu; David B Friedman; Carlos L Arteaga
Convergence of p53 and transforming growth factor beta (TGFbeta) signaling on activating expression of the tumor suppressor gene maspin in mammary epithelial cells.
The Journal of biological chemistry 2007;282(8):5661-9.
2006: Shizhen Emily Wang; Incheol Shin; Frederick Y Wu; David B Friedman; Carlos L Arteaga
HER2/Neu (ErbB2) signaling to Rac1-Pak1 is temporally and spatially modulated by transforming growth factor beta.
Cancer research 2006;66(19):9591-600.
2006: Shizhen Emily Wang; Archana Narasanna; Marianela Perez-Torres; Bin Xiang; Frederick Y Wu; seungchan yang; Graham Carpenter; Adi F Gazdar; Senthil K Muthuswamy; Carlos L Arteaga
HER2 kinase domain mutation results in constitutive phosphorylation and activation of HER2 and EGFR and resistance to EGFR tyrosine kinase inhibitors.
Cancer cell 2006;10(1):25-38.
2006: Frederick Y Wu; Shizhen Emily Wang; Melinda E Sanders; Incheol Shin; Federico Rojo; Jose Baselga; Carlos L Arteaga
Reduction of cytosolic p27(Kip1) inhibits cancer cell motility, survival, and tumorigenicity.
Cancer research 2006;66(4):2162-72.
2006: Jian Huang; Gangling Liao; Honglin Chen; Frederick Y Wu; Lindsey Hutt-Fletcher; Gary S Hayward; S Diane Hayward
Contribution of C/EBP proteins to Epstein-Barr virus lytic gene expression and replication in epithelial cells.
Journal of virology 2006;80(3):1098-109.
2005: Shizhen Emily Wang; Frederick Y Wu; Incheol Shin; Shimian Qu; Carlos L Arteaga
Transforming growth factor {beta} (TGF-{beta})-Smad target gene protein tyrosine phosphatase receptor type kappa is required for TGF-{beta} function.
Molecular and cellular biology 2005;25(11):4703-15.
2005: Incheol Shin; Jeremy Rotty; Frederick Y Wu; Carlos L Arteaga
Phosphorylation of p27Kip1 at Thr-157 interferes with its association with importin alpha during G1 and prevents nuclear re-entry.
The Journal of biological chemistry 2005;280(7):6055-63.
2005: Honglin Chen; Jian Huang; Frederick Y Wu; Gangling Liao; Lindsey Hutt-Fletcher; S Diane Hayward
Regulation of expression of the Epstein-Barr virus BamHI-A rightward transcripts.
Journal of virology 2005;79(3):1724-33.
2004: Frederick Y Wu; Shizhen Emily Wang; Honglin Chen; Ling Wang; S Diane Hayward; Gary S Hayward
CCAAT/enhancer binding protein alpha binds to the Epstein-Barr virus (EBV) ZTA protein through oligomeric interactions and contributes to cooperative transcriptional activation of the ZTA promoter through direct binding to the ZII and ZIIIB motifs during induction of the EBV lytic cycle.
Journal of virology 2004;78(9):4847-65.
2004: Shizhen Emily Wang; Frederick Y Wu; Honglin Chen; MEIR SHAMAY; Qizhi Zheng; Gary S Hayward
Early activation of the Kaposi's sarcoma-associated herpesvirus RTA, RAP, and MTA promoters by the tetradecanoyl phorbol acetate-induced AP1 pathway.
Journal of virology 2004;78(8):4248-67.
2003: Shizhen Emily Wang; Frederick Y Wu; YANXING YU; Gary S Hayward
CCAAT/enhancer-binding protein-alpha is induced during the early stages of Kaposi's sarcoma-associated herpesvirus (KSHV) lytic cycle reactivation and together with the KSHV replication and transcription activator (RTA) cooperatively stimulates the viral RTA, MTA, and PAN promoters.
Journal of virology 2003;77(17):9590-612.
2003: Frederick Y Wu; Shizhen Emily Wang; Qi-Qun Tang; Masahiro Fujimuro; Chuang-Jiun Chiou; Qizhi Zheng; Honglin Chen; S Diane Hayward; M Daniel Lane; Gary S Hayward
Cell cycle arrest by Kaposi's sarcoma-associated herpesvirus replication-associated protein is mediated at both the transcriptional and posttranslational levels by binding to CCAAT/enhancer-binding protein alpha and p21(CIP-1).
Journal of virology 2003;77(16):8893-914.
2003: Masahiro Fujimuro; Frederick Y Wu; Colette ApRhys; Henry Kajumbula; David B Young; Gary S Hayward; S Diane Hayward
A novel viral mechanism for dysregulation of beta-catenin in Kaposi's sarcoma-associated herpesvirus latency.
Nature medicine 2003;9(3):300-6.
2003: Frederick Y Wu; Honglin Chen; Shizhen Emily Wang; Colette ApRhys; Gangling Liao; Masahiro Fujimuro; Christopher J Farrell; Jian Huang; S Diane Hayward; Gary S Hayward
CCAAT/enhancer binding protein alpha interacts with ZTA and mediates ZTA-induced p21(CIP-1) accumulation and G(1) cell cycle arrest during the Epstein-Barr virus lytic cycle.
Journal of virology 2003;77(2):1481-500.
2003: Shizhen Emily Wang; Frederick Y Wu; Masahiro Fujimuro; jianchao zong; S Diane Hayward; Gary S Hayward
Role of CCAAT/enhancer-binding protein alpha (C/EBPalpha) in activation of the Kaposi's sarcoma-associated herpesvirus (KSHV) lytic-cycle replication-associated protein (RAP) promoter in cooperation with the KSHV replication and transcription activator (RTA) and RAP.
Journal of virology 2003;77(1):600-23.
2002: Frederick Y Wu; Qi-Qun Tang; Honglin Chen; Colette ApRhys; Christopher Farrell; Jianmeng Chen; Masahiro Fujimuro; M Daniel Lane; Gary S Hayward
Lytic replication-associated protein (RAP) encoded by Kaposi sarcoma-associated herpesvirus causes p21CIP-1-mediated G1 cell cycle arrest through CCAAT/enhancer-binding protein-alpha.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(16):10683-8.
2002: Keqiang Ye; Bahman Aghdasi; Hongbo R Luo; John L Moriarity; Frederick Y Wu; Jenny J Hong; K Joseph Hurt; Sun Sik Bae; Pann-Ghill Suh; Solomon H Snyder
Phospholipase C gamma 1 is a physiological guanine nucleotide exchange factor for the nuclear GTPase PIKE.
Nature 2002;415(6871):541-4.
2001: Gangling Liao; Frederick Y Wu; S Diane Hayward
Interaction with the Epstein-Barr virus helicase targets Zta to DNA replication compartments.
Journal of virology 2001;75(18):8792-802.
2001: Dolores M Ciufo; Jennifer S Cannon; Lynn J Poole; Frederick Y Wu; P Murray; Richard F Ambinder; Gary S Hayward
Spindle cell conversion by Kaposi's sarcoma-associated herpesvirus: formation of colonies and plaques with mixed lytic and latent gene expression in infected primary dermal microvascular endothelial cell cultures.
Journal of virology 2001;75(12):5614-26.
2001: Frederick Y Wu; JIN HYUN AHN; Donald J Alcendor; Won-Jong Jang; J Xiao; S Diane Hayward; Gary S Hayward
Origin-independent assembly of Kaposi's sarcoma-associated herpesvirus DNA replication compartments in transient cotransfection assays and association with the ORF-K8 protein and cellular PML.
Journal of virology 2001;75(3):1487-506.
2000: Keqiang Ye; K Joseph Hurt; Frederick Y Wu; M Fang; Hongbo R Luo; Jenny J Hong; Seth Blackshaw; Christopher D Ferris; Solomon H Snyder
Pike. A nuclear gtpase that enhances PI3kinase activity and is regulated by protein 4.1N.
Cell 2000;103(6):919-30.