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Dirk Brenner

Research Profile

Chemicals & Drugs

Anatomy

Concepts & Ideas

Protein Structure, Tertiary

Physiology

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Publications

TOP 3
Katalin Darvas; Simone Rosenberger; Dirk Brenner; Cornelius Fritsch; Nadine Gmelin; Peter H Krammer; Frank Rösl
Histone deacetylase inhibitor-induced sensitization to TNFalpha/TRAIL-mediated apoptosis in cervical carcinoma cells is dependent on HPV oncogene expression.
Dirk Brenner; Markus Brechmann; Simone Röhling; Myriam Tapernoux; Thomas Mock; Dominic Winter; Wolf D Lehmann; Friedemann Kiefer; Margot Thome; Peter H Krammer; Rüdiger Arnold
Phosphorylation of CARMA1 by HPK1 is critical for NF-kappaB activation in T cells.
Claus-Detlev Klemke; Dirk Brenner; Eva-Maria Weiss; Marc Schmidt; Martin Leverkus; Karsten Gülow; Peter H Krammer
Lack of T-cell receptor-induced signaling is crucial for CD95 ligand up-regulation and protects cutaneous T-cell lymphoma cells from activation-induced cell death.

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All Publications

2010: Katalin Darvas; Simone Rosenberger; Dirk Brenner; Cornelius Fritsch; Nadine Gmelin; Peter H Krammer; Frank Rösl
Histone deacetylase inhibitor-induced sensitization to TNFalpha/TRAIL-mediated apoptosis in cervical carcinoma cells is dependent on HPV oncogene expression.
International journal of cancer. Journal international du cancer 2010;127(6):1384-92.
2009: Dirk Brenner; Markus Brechmann; Simone Röhling; Myriam Tapernoux; Thomas Mock; Dominic Winter; Wolf D Lehmann; Friedemann Kiefer; Margot Thome; Peter H Krammer; Rüdiger Arnold
Phosphorylation of CARMA1 by HPK1 is critical for NF-kappaB activation in T cells.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(34):14508-13.
2009: Claus-Detlev Klemke; Dirk Brenner; Eva-Maria Weiss; Marc Schmidt; Martin Leverkus; Karsten Gülow; Peter H Krammer
Lack of T-cell receptor-induced signaling is crucial for CD95 ligand up-regulation and protects cutaneous T-cell lymphoma cells from activation-induced cell death.
Cancer research 2009;69(10):4175-83.
2008: Dirk Brenner; Peter H Krammer; Rüdiger Arnold
Concepts of activated T cell death.
Critical reviews in oncology/hematology 2008;66(1):52-64.
2007: Dirk Brenner; Alexander Golks; Mareike Becker; Wolfgang Müller; Christian R Frey; Rostislav Novak; Doron Melamed; Friedemann Kiefer; Peter H Krammer; Rüdiger Arnold
Caspase-cleaved HPK1 induces CD95L-independent activation-induced cell death in T and B lymphocytes.
Blood 2007;110(12):3968-77.
2007: R Arnold; C R Frey; W Müller; Dirk Brenner; Peter H Krammer; F Kiefer
Sustained JNK signaling by proteolytically processed HPK1 mediates IL-3 independent survival during monocytic differentiation.
Cell death and differentiation 2007;14(3):568-75.
2006: Stefanie C Fas; Sven Baumann; Andreas Krueger; Christian R Frey; Henning Schulze-Bergkamen; Dirk Brenner; Christine Stumpf; Kathrin Kappes; Peter H Krammer
In vitro generated human memory-like T cells are CD95 type II cells and resistant towards CD95-mediated apoptosis.
European journal of immunology 2006;36(11):2894-903.
2006: Rüdiger Arnold; Dirk Brenner; Mareike Becker; Christian R Frey; Peter H Krammer
How T lymphocytes switch between life and death.
European journal of immunology 2006;36(7):1654-8.
2006: Alexander Golks; Dirk Brenner; Peter H Krammer; Inna N Lavrik
The c-FLIP-NH2 terminus (p22-FLIP) induces NF-kappaB activation.
The Journal of experimental medicine 2006;203(5):1295-305.
2006: Alexander Golks; Dirk Brenner; Ingo Schmitz; Carsten Watzl; Andreas Krueger; Peter H Krammer; Inna N Lavrik
The role of CAP3 in CD95 signaling: new insights into the mechanism of procaspase-8 activation.
Cell death and differentiation 2006;13(3):489-98.
2005: Dirk Brenner; Alexander Golks; Friedemann Kiefer; Peter H Krammer; Rüdiger Arnold
Activation or suppression of NFkappaB by HPK1 determines sensitivity to activation-induced cell death.
The EMBO journal 2005;24(24):4279-90.
2005: Alexander Golks; Dirk Brenner; Cornelius Fritsch; Peter H Krammer; Inna N Lavrik
c-FLIPR, a new regulator of death receptor-induced apoptosis.
The Journal of biological chemistry 2005;280(15):14507-13.
2004: Patrick Finzer; Andreas Krueger; Michael Stöhr; Dirk Brenner; Ubaldo Soto; Christian Kuntzen; Peter H Krammer; Frank Rösl
HDAC inhibitors trigger apoptosis in HPV-positive cells by inducing the E2F-p73 pathway.
Oncogene 2004;23(28):4807-17.
2004: Henning Schulze-Bergkamen; Dirk Brenner; Andreas Krueger; Dorothee Suess; Stefanie C Fas; Christian R Frey; Andreas Dax; Dorothea Zink; Peter Büchler; Martina Müller; Peter H Krammer
Hepatocyte growth factor induces Mcl-1 in primary human hepatocytes and inhibits CD95-mediated apoptosis via Akt.
Hepatology (Baltimore, Md.) 2004;39(3):645-54.
1999: Dirk Brenner; Rüdiger Gerstberger
Functional receptors in the avian kidney for C-type natriuretic peptide.
Endocrinology 1999;140(4):1622-9.