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Kenneth Wu

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
33
Folsom, Aaron
18
Aleksic, Nena
15
Tsai, Ah-Lim
15
Wang, Lee-Ho
13
Liou, Jun-Yang
12
Deng, Wu-Guo
10
Ruan, Ke-He
9
Shyue, Song-Kun
9
Juneja, Harinder
9
Chen, Pei-Feng
8
Huang, Jaou-Chen
8
Matijevic-Aleksic, Nena
8
Zhu, Ying
7
Saunders, Michael
7
Goldsby, Jennifer

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Publications

TOP 3
Chen Pei-Feng; Wu Kenneth K
Two synthetic peptides corresponding to the proximal heme-binding domain and CD1 domain of human endothelial nitric-oxide synthase inhibit the oxygenase activity by interacting with CaM.
Wu Jui-Sheng; Cheung Wai-Mui; Tsai Yau-Sheng; Chen Yi-Tong; Fong Wen-Hsuan; Tsai Hsin-Da; Chen Yu-Chang; Liou Jun-Yang; Shyue Song-Kun; Chen Jin-Jer; Chen Y Eugene; Maeda Nobuyo; Wu Kenneth K; Lin Teng-Nan
Ligand-activated peroxisome proliferator-activated receptor-gamma protects against ischemic cerebral infarction and neuronal apoptosis by 14-3-3 epsilon upregulation.
Aleksic Nena; Wang Yao-Wei W; Ahn Chul; Juneja Harinder S; Folsom Aaron R; Wu Kenneth K
Assessment of coronary heart disease risk by combined analysis of coagulation factors.

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All Publications

2009: Chen Pei-Feng; Wu Kenneth K
Two synthetic peptides corresponding to the proximal heme-binding domain and CD1 domain of human endothelial nitric-oxide synthase inhibit the oxygenase activity by interacting with CaM.
Archives of biochemistry and biophysics 2009;486(2):132-40.
2009: Wu Jui-Sheng; Cheung Wai-Mui; Tsai Yau-Sheng; Chen Yi-Tong; Fong Wen-Hsuan; Tsai Hsin-Da; Chen Yu-Chang; Liou Jun-Yang; Shyue Song-Kun; Chen Jin-Jer; Chen Y Eugene; Maeda Nobuyo; Wu Kenneth K; Lin Teng-Nan
Ligand-activated peroxisome proliferator-activated receptor-gamma protects against ischemic cerebral infarction and neuronal apoptosis by 14-3-3 epsilon upregulation.
Circulation 2009;119(8):1124-34.
2008: Aleksic Nena; Wang Yao-Wei W; Ahn Chul; Juneja Harinder S; Folsom Aaron R; Wu Kenneth K
Assessment of coronary heart disease risk by combined analysis of coagulation factors.
Atherosclerosis 2008;198(2):294-300.
2008: Kohsaka Shun; Volcik Kelly A; Folsom Aaron R; Wu Kenneth K; Ballantyne Christie M; Willerson James T; Boerwinkle Eric
Increased risk of incident stroke associated with the cyclooxygenase 2 (COX-2) G-765C polymorphism in African-Americans: the Atherosclerosis Risk in Communities Study.
Atherosclerosis 2008;196(2):926-30.
2007: Huang Jaou-Chen; Wun Wan-Song A; Goldsby Jennifer S; Egan Karine; FitzGerald Garret A; Wu Kenneth K
Prostacyclin receptor signaling and early embryo development in the mouse.
Human reproduction (Oxford, England) 2007;22(11):2851-6.
2007: Liou Jun-Yang; Matijevic-Aleksic Nena; Lee Sang; Wu Kenneth K
Prostacyclin inhibits endothelial cell XIAP ubiquitination and degradation.
Journal of cellular physiology 2007;212(3):840-8.
2007: Deng Wu-Guo; Montero Alberto J; Wu Kenneth K
Interferon-gamma suppresses cyclooxygenase-2 promoter activity by inhibiting C-Jun and C/EBPbeta binding.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(8):1752-9.
2007: Wu Kenneth K
Differential cyclooxygenase-2 transcriptional control in proliferating versus quiescent fibroblasts.
Prostaglandins & other lipid mediators 2007;83(3):175-81.
2007: Liou Jun-Yang; Ellent David P; Lee Sang; Goldsby Jennifer; Ko Bor-Sheng; Matijevic Nena; Huang Jaou-Chen; Wu Kenneth K
Cyclooxygenase-2-derived prostaglandin e2 protects mouse embryonic stem cells from apoptosis.
Stem cells (Dayton, Ohio) 2007;25(5):1096-103.
2007: Liou Jun-Yang; Ghelani Dipak; Yeh Sam; Wu Kenneth K
Nonsteroidal anti-inflammatory drugs induce colorectal cancer cell apoptosis by suppressing 14-3-3epsilon.
Cancer research 2007;67(7):3185-91.
2007: Huang J-C; Wun W-S A; Goldsby J S; Wun I C; Noorhasan D; Wu K K
Stimulation of embryo hatching and implantation by prostacyclin and peroxisome proliferator-activated receptor delta activation: implication in IVF.
Human reproduction (Oxford, England) 2007;22(3):807-14.
2006: Cieslik Katarzyna A; Deng Wu-Guo; Wu Kenneth K
Essential role of C-Rel in nitric-oxide synthase-2 transcriptional activation: time-dependent control by salicylate.
Molecular pharmacology 2006;70(6):2004-14.
2006: Wu Kenneth K
Transcription-based COX-2 inhibition: a therapeutic strategy.
Thrombosis and haemostasis 2006;96(4):417-22.
2006: Liou Jun-Yang; Lee Sang; Ghelani Dipak; Matijevic-Aleksic Nevenka; Wu Kenneth K
Protection of endothelial survival by peroxisome proliferator-activated receptor-delta mediated 14-3-3 upregulation.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(7):1481-7.
2006: Deng Wu-Guo; Tang Shao-Tzu; Tseng Hui-Ping; Wu Kenneth K
Melatonin suppresses macrophage cyclooxygenase-2 and inducible nitric oxide synthase expression by inhibiting p52 acetylation and binding.
Blood 2006;108(2):518-24.
2006: Lin Teng-Nan; Cheung Wai-Mui; Wu Jui-Sheng; Chen Jean-Ju; Lin Heng; Chen Jin-Jer; Liou Jun-Yang; Shyue Song-Kun; Wu Kenneth K
15d-prostaglandin J2 protects brain from ischemia-reperfusion injury.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(3):481-7.
2006: Wu Kenneth K
Analysis of protein-DNA binding by streptavidin-agarose pulldown.
Methods in molecular biology (Clifton, N.J.) 2006;338():281-90.
2005: Wu Kenneth K; Liou Jun-Yang
Cellular and molecular biology of prostacyclin synthase.
Biochemical and biophysical research communications 2005;338(1):45-52.
2005: Liou Jun-Yang; Aleksic Nena; Chen Shu-Fen; Han Tsai-Jung; Shyue Song-Kun; Wu Kenneth K
Mitochondrial localization of cyclooxygenase-2 and calcium-independent phospholipase A2 in human cancer cells: implication in apoptosis resistance.
Experimental cell research 2005;306(1):75-84.
2005: Cieslik Katarzyna A; Zhu Ying; Shtivelband Mikhail; Wu Kenneth K
Inhibition of p90 ribosomal S6 kinase-mediated CCAAT/enhancer-binding protein beta activation and cyclooxygenase-2 expression by salicylate.
The Journal of biological chemistry 2005;280(18):18411-7.
2005: Wu Kenneth K; Liou Jun-Yang; Cieslik Katarzyna
Transcriptional Control of COX-2 via C/EBPbeta.
Arteriosclerosis, thrombosis, and vascular biology 2005;25(4):679-85.
2005: Wu K K
Control of cyclooxygenase-2 transcriptional activation by pro-inflammatory mediators.
Prostaglandins, leukotrienes, and essential fatty acids 2005;72(2):89-93.
2005: Wu Kenneth K; Matijevic-Aleksic Nena
Molecular aspects of thrombosis and antithrombotic drugs.
Critical reviews in clinical laboratory sciences 2005;42(3):249-77.
2005: Wu Kenneth K
Novel mechanisms of aspirin pharmacologic actions: a model for studying herbal natural products.
Thrombosis research 2005;117(1-2):61-4; discussion 65-7.
2004: Huang Jaou-Chen; Goldsby Jennifer S; Arbab Farinaz; Melhem Ziad; Aleksic Nena; Wu Kenneth K
Oviduct prostacyclin functions as a paracrine factor to augment the development of embryos.
Human reproduction (Oxford, England) 2004;19(12):2907-12.
2004: Huang Jaou-Chen; Wun W-S Alfred; Goldsby Jennifer S; Matijevic-Aleksic Nena; Wu Kenneth K
Cyclooxygenase-2-derived endogenous prostacyclin enhances mouse embryo hatching.
Human reproduction (Oxford, England) 2004;19(12):2900-6.
2004: Deng Wu-Guo; Zhu Ying; Wu Kenneth K
Role of p300 and PCAF in regulating cyclooxygenase-2 promoter activation by inflammatory mediators.
Blood 2004;103(6):2135-42.
2004: Afshar-Kharghan Vahid; Matijevic-Aleksic Nevenka; Ahn Chul; Boerwinkle Eric; Wu Kenneth K; López José A
The variable number of tandem repeat polymorphism of platelet glycoprotein Ibalpha and risk of coronary heart disease.
Blood 2004;103(3):963-5.
2003: Deng Wu-Guo; Wu Kenneth K
Regulation of inducible nitric oxide synthase expression by p300 and p50 acetylation.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(12):6581-8.
2003: Huang J-C; Wun W-S A; Goldsby J S; Wun I C; Falconi S M; Wu K K
Prostacyclin enhances embryo hatching but not sperm motility.
Human reproduction (Oxford, England) 2003;18(12):2582-9.
2003: Deng Wu-Guo; Zhu Ying; Montero Alberto; Wu Kenneth K
Quantitative analysis of binding of transcription factor complex to biotinylated DNA probe by a streptavidin-agarose pulldown assay.
Analytical biochemistry 2003;323(1):12-8.
2003: Chen Pei-Feng; Wu Kenneth K
Structural elements contribute to the calcium/calmodulin dependence on enzyme activation in human endothelial nitric-oxide synthase.
The Journal of biological chemistry 2003;278(52):52392-400.
2003: Shtivelband M I; Juneja H S; Lee S; Wu K K
Aspirin and salicylate inhibit colon cancer medium- and VEGF-induced endothelial tube formation: correlation with suppression of cyclooxygenase-2 expression.
Journal of thrombosis and haemostasis : JTH 2003;1(10):2225-33.
2003: Wu Kenneth K
Soluble thrombomodulin and coronary heart disease.
Current opinion in lipidology 2003;14(4):373-5.
2003: Wu Kenneth K
Control of COX-2 and iNOS gene expressions by aspirin and salicylate.
Thrombosis research 2003;110(5-6):273-6.
2003: Wu Kenneth K
Aspirin and other cyclooxygenase inhibitors: new therapeutic insights.
Seminars in vascular medicine 2003;3(2):107-12.
2003: Wu Kenneth K; Aleksic Nena; Ballantyne Christie M; Ahn Chul; Juneja Harinder; Boerwinkle Eric
Interaction between soluble thrombomodulin and intercellular adhesion molecule-1 in predicting risk of coronary heart disease.
Circulation 2003;107(13):1729-32.
2003: Chen Pei-Feng; Berka Vladimir; Wu Kenneth K
Differential effects of mutations in human endothelial nitric oxide synthase at residues Tyr-357 and Arg-365 on L-arginine hydroxylation and GN-hydroxy-L-arginine oxidation.
Archives of biochemistry and biophysics 2003;411(1):83-92.
2003: Deng Wu-Guo; Zhu Ying; Wu Kenneth K
Up-regulation of p300 binding and p50 acetylation in tumor necrosis factor-alpha-induced cyclooxygenase-2 promoter activation.
The Journal of biological chemistry 2003;278(7):4770-7.
2003: Aleksic N; Folsom A R; Cushman M; Heckbert S R; Tsai M Y; Wu K K
Prospective study of the A455V polymorphism in the thrombomodulin gene, plasma thrombomodulin, and incidence of venous thromboembolism: the LITE Study.
Journal of thrombosis and haemostasis : JTH 2003;1(1):88-94.
2002: Cieslik Katarzyna; Zhu Ying; Wu Kenneth K
Salicylate suppresses macrophage nitric-oxide synthase-2 and cyclo-oxygenase-2 expression by inhibiting CCAAT/enhancer-binding protein-beta binding via a common signaling pathway.
The Journal of biological chemistry 2002;277(51):49304-10.
2002: Huang Jaou-Chen; Arbab Farinaz; Tumbusch Katherine J; Goldsby Jennifer S; Matijevic-Aleksic Nena; Wu Kenneth K
Human fallopian tubes express prostacyclin (PGI) synthase and cyclooxygenases and synthesize abundant PGI.
The Journal of clinical endocrinology and metabolism 2002;87(9):4361-8.
2002: Folsom Aaron R; Aleksic Nena; Catellier Diane; Juneja Harinder S; Wu Kenneth K
C-reactive protein and incident coronary heart disease in the Atherosclerosis Risk In Communities (ARIC) study.
American heart journal 2002;144(2):233-8.
2002: Deng Wu-Guo; Saunders Michael A; Gilroy Derek W; He Xue-Zhong; Yeh Howard; Zhu Ying; Shtivelband Mikhail I; Ruan Ke-He; Wu Kenneth K
Purification and characterization of a cyclooxygenase-2 and angiogenesis suppressing factor produced by human fibroblasts.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(10):1286-8.
2002: Folsom Aaron R; Aleksic Nena; Wang Lu; Cushman Mary; Wu Kenneth K; White Richard H
Protein C, antithrombin, and venous thromboembolism incidence: a prospective population-based study.
Arteriosclerosis, thrombosis, and vascular biology 2002;22(6):1018-22.
2002: Schroer Karsten; Zhu Ying; Saunders Michael A; Deng Wu-Guo; Xu Xiao-Ming; Meyer-Kirchrath Jutta; Wu Kenneth K
Obligatory role of cyclic adenosine monophosphate response element in cyclooxygenase-2 promoter induction and feedback regulation by inflammatory mediators.
Circulation 2002;105(23):2760-5.
2002: Schreiner Pamela J; Wu Kenneth K; Malinow M Rene; Stinson Valarie L; Szklo Moyses; Nieto F Javier; Heiss Gerardo
Hyperhomocyst(e)inemia and hemostatic factors: the atherosclerosis risk in communities study.
Annals of epidemiology 2002;12(4):228-36.
2002: Lin Heng; Lin Teng-Nan; Cheung Wai-Mui; Nian Gau-Ming; Tseng Ping-Hui; Chen Shu-Fen; Chen Jean-Ju; Shyue Song-Kun; Liou Jun-Yang; Wu Cheng-Wen; Wu Kenneth K
Cyclooxygenase-1 and bicistronic cyclooxygenase-1/prostacyclin synthase gene transfer protect against ischemic cerebral infarction.
Circulation 2002;105(16):1962-9.
2002: Zhu Ying; Saunders Michael A; Yeh Howard; Deng Wu-guo; Wu Kenneth K
Dynamic regulation of cyclooxygenase-2 promoter activity by isoforms of CCAAT/enhancer-binding proteins.
The Journal of biological chemistry 2002;277(9):6923-8.
2002: Aleksic Nena; Ahn Chul; Wang Yao-Wei; Juneja Harinder; Folsom Aaron R; Boerwinkle Eric; Wu Kenneth K
Factor XIIIA Val34Leu polymorphism does not predict risk of coronary heart disease: The Atherosclerosis Risk in Communities (ARIC) Study.
Arteriosclerosis, thrombosis, and vascular biology 2002;22(2):348-52.
2001: Deng W G; Ruan K H; Du M; Saunders M A; Wu K K
Aspirin and salicylate bind to immunoglobulin heavy chain binding protein (BiP) and inhibit its ATPase activity in human fibroblasts.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(13):2463-70.
2001: Juan S H; Lee T S; Tseng K W; Liou J Y; Shyue S K; Wu K K; Chau L Y
Adenovirus-mediated heme oxygenase-1 gene transfer inhibits the development of atherosclerosis in apolipoprotein E-deficient mice.
Circulation 2001;104(13):1519-25.
2001: Liou J Y; Deng W G; Gilroy D W; Shyue S K; Wu K K
Colocalization and interaction of cyclooxygenase-2 with caveolin-1 in human fibroblasts.
The Journal of biological chemistry 2001;276(37):34975-82.
2001: Salomaa V; Matei C; Aleksic N; Sansores-Garcia L; Folsom A R; Juneja H; Park E; Wu K K
Cross-sectional association of soluble thrombomodulin with mild peripheral artery disease; the ARIC study. Atherosclerosis Risk in Communities.
Atherosclerosis 2001;157(2):309-14.
2001: Gilroy D W; Saunders M A; Wu K K
COX-2 expression and cell cycle progression in human fibroblasts.
American journal of physiology. Cell physiology 2001;281(1):C188-94.
2001: Saunders M A; Sansores-Garcia L; Gilroy D W; Wu K K
Selective suppression of CCAAT/enhancer-binding protein beta binding and cyclooxygenase-2 promoter activity by sodium salicylate in quiescent human fibroblasts.
The Journal of biological chemistry 2001;276(22):18897-904.
2001: Logothetis C J; Wu K K; Finn L D; Daliani D; Figg W; Ghaddar H; Gutterman J U
Phase I trial of the angiogenesis inhibitor TNP-470 for progressive androgen-independent prostate cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(5):1198-203.
2001: Shyue S K; Tsai M J; Liou J Y; Willerson J T; Wu K K
Selective augmentation of prostacyclin production by combined prostacyclin synthase and cyclooxygenase-1 gene transfer.
Circulation 2001;103(16):2090-5.
2001: Folsom A R; Aleksic N; Park E; Salomaa V; Juneja H; Wu K K
Prospective study of fibrinolytic factors and incident coronary heart disease: the Atherosclerosis Risk in Communities (ARIC) Study.
Arteriosclerosis, thrombosis, and vascular biology 2001;21(4):611-7.
2001: Folsom A R; Aleksic N; Ahn C; Boerwinkle E; Wu K K
Beta-fibrinogen gene -455G/A polymorphism and coronary heart disease incidence: the Atherosclerosis Risk in Communities (ARIC) Study.
Annals of epidemiology 2001;11(3):166-70.
2001: Wu K K; Aleksic N; Ahn C; Boerwinkle E; Folsom A R; Juneja H;
Thrombomodulin Ala455Val polymorphism and risk of coronary heart disease.
Circulation 2001;103(10):1386-9.
2001: Gilroy D W; Saunders M A; Sansores-Garcia L; Matijevic-Aleksic N; Wu K K
Cell cycle-dependent expression of cyclooxygenase-2 in human fibroblasts.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(2):288-90.
2001: Cieslik K; Abrams C S; Wu K K
Up-regulation of endothelial nitric-oxide synthase promoter by the phosphatidylinositol 3-kinase gamma /Janus kinase 2/MEK-1-dependent pathway.
The Journal of biological chemistry 2001;276(2):1211-9.
2000: Aleksic N; Juneja H; Folsom A R; Ahn C; Boerwinkle E; Chambless L E; Wu K K
Platelet Pl(A2) allele and incidence of coronary heart disease: results from the Atherosclerosis Risk In Communities (ARIC) Study.
Circulation 2000;102(16):1901-5.
2000: Liou J Y; Shyue S K; Tsai M J; Chung C L; Chu K Y; Wu K K
Colocalization of prostacyclin synthase with prostaglandin H synthase-1 (PGHS-1) but not phorbol ester-induced PGHS-2 in cultured endothelial cells.
The Journal of biological chemistry 2000;275(20):15314-20.
2000: Chen P F; Wu K K
Characterization of the roles of the 594-645 region in human endothelial nitric-oxide synthase in regulating calmodulin binding and electron transfer.
The Journal of biological chemistry 2000;275(17):13155-63.
2000: Folsom A R; Wu K K; Rasmussen M; Chambless L E; Aleksic N; Nieto F J
Determinants of population changes in fibrinogen and factor VII over 6 years: the Atherosclerosis Risk in Communities (ARIC) Study.
Arteriosclerosis, thrombosis, and vascular biology 2000;20(2):601-6.
1999: Cieslik K; Lee C M; Tang J L; Wu K K
Transcriptional regulation of endothelial nitric-oxide synthase by an interaction between casein kinase 2 and protein phosphatase 2A.
The Journal of biological chemistry 1999;274(49):34669-75.
1999: Folsom A R; Rosamond W D; Shahar E; Cooper L S; Aleksic N; Nieto F J; Rasmussen M L; Wu K K
Prospective study of markers of hemostatic function with risk of ischemic stroke. The Atherosclerosis Risk in Communities (ARIC) Study Investigators.
Circulation 1999;100(7):736-42.
1999: Salomaa V; Matei C; Aleksic N; Sansores-Garcia L; Folsom A R; Juneja H; Chambless L E; Wu K K
Soluble thrombomodulin as a predictor of incident coronary heart disease and symptomless carotid artery atherosclerosis in the Atherosclerosis Risk in Communities (ARIC) Study: a case-cohort study.
Lancet 1999;353(9166):1729-34.
1999: Xu X M; Sansores-Garcia L; Chen X M; Matijevic-Aleksic N; Du M; Wu K K
Suppression of inducible cyclooxygenase 2 gene transcription by aspirin and sodium salicylate.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(9):5292-7.
1999: Wu K K; Aleksic N
Platelet glycoprotein polymorphism and risk for coronary heart disease.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 1999;10 Suppl 1():S63-5.
1998: Ghaddar H M; Folsom A R; Aleksic N; Hearne L B; Chambless L E; Morrissey J H; Wu K K
Correlation of factor VIIa values with factor VII gene polymorphism, fasting and postprandial triglyceride levels, and subclinical carotid atherosclerosis.
Circulation 1998;98(25):2815-21.
1998: Chen P F; Berka V; Tsai A L; Wu K K
Effects of Asp-369 and Arg-372 mutations on heme environment and function in human endothelial nitric-oxide synthase.
The Journal of biological chemistry 1998;273(51):34164-70.
1998: Folsom A R; Peacock J M; Nieto F J; Rosamond W D; Eigenbrodt M L; Davis C E; Wu K K
Plasma fibrinogen and incident hypertension in the Atherosclerosis Risk in Communities (ARIC) Study.
Journal of hypertension 1998;16(11):1579-83.
1998: Du M; Sansores-Garcia L; Zu Z; Wu K K
Cloning and expression analysis of a novel salicylate suppressible gene, Hs-CUL-3, a member of cullin/Cdc53 family.
The Journal of biological chemistry 1998;273(38):24289-92.
1998: Cieslik K; Zembowicz A; Tang J L; Wu K K
Transcriptional regulation of endothelial nitric-oxide synthase by lysophosphatidylcholine.
The Journal of biological chemistry 1998;273(24):14885-90.
1998: Wu K K
Biochemical pharmacology of nonsteroidal anti-inflammatory drugs.
Biochemical pharmacology 1998;55(5):543-7.
1998: Huang J C; Liu D Y; Yadollahi S; Wu K K; Dawood M Y
Interleukin-1 beta induces cyclooxygenase-2 gene expression in cultured endometrial stromal cells.
The Journal of clinical endocrinology and metabolism 1998;83(2):538-41.
1997: Wu K K
Genetic markers: genes involved in thrombosis.
Journal of cardiovascular risk 1997;4(5-6):347-52.
1997: Folsom A R; Wu K K; Rosamond W D; Sharrett A R; Chambless L E
Prospective study of hemostatic factors and incidence of coronary heart disease: the Atherosclerosis Risk in Communities (ARIC) Study.
Circulation 1997;96(4):1102-8.
1997: Xu X M; Tang J L; Chen X; Wang L H; Wu K K
Involvement of two Sp1 elements in basal endothelial prostaglandin H synthase-1 promoter activity.
The Journal of biological chemistry 1997;272(11):6943-50.
1997: Chen P F; Tsai A L; Berka V; Wu K K
Mutation of Glu-361 in human endothelial nitric-oxide synthase selectively abolishes L-arginine binding without perturbing the behavior of heme and other redox centers.
The Journal of biological chemistry 1997;272(10):6114-8.
1997: Shyue S K; Ruan K H; Wang L H; Wu K K
Prostacyclin synthase active sites. Identification by molecular modeling-guided site-directed mutagenesis.
The Journal of biological chemistry 1997;272(6):3657-62.
1997: Pankow J S; Folsom A R; Province M A; Rao D C; Eckfeldt J; Heiss G; Shahar E; Wu K K
Family history of coronary heart disease and hemostatic variables in middle-aged adults. Atherosclerosis Risk in Communities Investigators and Family Heart Study Research Group.
Thrombosis and haemostasis 1997;77(1):87-93.
1997: Wu K K
Regulation of prostaglandin H synthase-1 gene expression.
Advances in experimental medicine and biology 1997;400A():121-6.
1996: Tazawa R; Green E D; Ohashi K; Wu K K; Wang L H
Characterization of the complete genomic structure of human thromboxane synthase gene and functional analysis of its promoter.
Archives of biochemistry and biophysics 1996;334(2):349-56.
1996: Wu K K
Endothelial prostaglandin and nitric oxide synthesis in atherogenesis and thrombosis.
Journal of the Formosan Medical Association = Taiwan yi zhi 1996;95(9):661-6.
1996: Wu K K
Cyclooxygenase 2 induction: molecular mechanism and pathophysiologic roles.
The Journal of laboratory and clinical medicine 1996;128(3):242-5.
1996: Wang L H; Matijevic-Aleksic N; Hsu P Y; Ruan K H; Wu K K; Kulmacz R J
Identification of thromboxane A2 synthase active site residues by molecular modeling-guided site-directed mutagenesis.
The Journal of biological chemistry 1996;271(33):19970-5.
1996: Chen P F; Tsai A L; Berka V; Wu K K
Endothelial nitric-oxide synthase. Evidence for bidomain structure and successful reconstitution of catalytic activity from two separate domains generated by a baculovirus expression system.
The Journal of biological chemistry 1996;271(24):14631-5.
1996: Shahar E; Folsom A R; Salomaa V V; Stinson V L; McGovern P G; Shimakawa T; Chambless L E; Wu K K
Relation of hormone-replacement therapy to measures of plasma fibrinolytic activity. Atherosclerosis Risk in Communities (ARIC) Study Investigators.
Circulation 1996;93(11):1970-5.
1996: Xu X M; Tang J L; Hajibeigi A; Loose-Mitchell D S; Wu K K
Transcriptional regulation of endothelial constitutive PGHS-1 expression by phorbol ester.
The American journal of physiology 1996;270(1 Pt 1):C259-64.
1996: Zoldhelyi P; McNatt J; Xu X M; Loose-Mitchell D; Meidell R S; Clubb F J; Buja L M; Willerson J T; Wu K K
Prevention of arterial thrombosis by adenovirus-mediated transfer of cyclooxygenase gene.
Circulation 1996;93(1):10-7.
1996: Matijevic-Aleksic N; McPhedran P; Wu K K
Bleeding disorder due to platelet prostaglandin H synthase-1 (PGHS-1) deficiency.
British journal of haematology 1996;92(1):212-7.
1996: Wu K K; Thiagarajan P
Role of endothelium in thrombosis and hemostasis.
Annual review of medicine 1996;47():315-31.
1995: Matijevic-Aleksic N; Sanduja S K; Wang L H; Wu K K
Differential expression of thromboxane A synthase and prostaglandin H synthase in megakaryocytic cell line.
Biochimica et biophysica acta 1995;1269(2):167-75.
1995: Chen P F; Tsai A L; Wu K K
Cysteine 99 of endothelial nitric oxide synthase (NOS-III) is critical for tetrahydrobiopterin-dependent NOS-III stability and activity.
Biochemical and biophysical research communications 1995;215(3):1119-29.
1995: Zembowicz A; Jones S L; Wu K K
Induction of cyclooxygenase-2 in human umbilical vein endothelial cells by lysophosphatidylcholine.
The Journal of clinical investigation 1995;96(3):1688-92.
1995: Tang J L; Zembowicz A; Xu X M; Wu K K
Role of Sp1 in transcriptional activation of human nitric oxide synthase type III gene.
Biochemical and biophysical research communications 1995;213(2):673-80.
1995: Zembowicz A; Tang J L; Wu K K
Transcriptional induction of endothelial nitric oxide synthase type III by lysophosphatidylcholine.
The Journal of biological chemistry 1995;270(28):17006-10.
1995: Nguyen N D; Ghaddar H; Stinson V; Chambless L E; Wu K K
ARIC hemostasis study--IV. Intraindividual variability and reliability of hemostatic factors. The Atherosclerosis Risk in Communities (ARIC).
Thrombosis and haemostasis 1995;73(2):256-60.
1995: Salomaa V; Stinson V; Kark J D; Folsom A R; Davis C E; Wu K K
Association of fibrinolytic parameters with early atherosclerosis. The ARIC Study. Atherosclerosis Risk in Communities Study.
Circulation 1995;91(2):284-90.
1995: Wu K K; Zoldhelyi P; Willerson J T; Meidell R; McNatt J; Xu X M
Restoration of prostacyclin synthesis by transfer of prostaglandin H synthase cDNA.
Advances in prostaglandin, thromboxane, and leukotriene research 1995;23():377-9.
1995: Xu X M; Hajibeige A; Tazawa R; Loose-Mitchell D; Wang L H; Wu K K
Characterization of human prostaglandin H synthase genes.
Advances in prostaglandin, thromboxane, and leukotriene research 1995;23():105-7.
1995: Wu K K
Molecular regulation and augmentation of prostacyclin biosynthesis.
Agents and actions. Supplements 1995;45():11-7.
1995: Willerson J T; Zoldhelyi P; Meidell R; McNatt J; Xu X M; Wu K K
Gene therapy to restore prostacyclin presence to injured endothelium.
Transactions of the American Clinical and Climatological Association 1995;106():100-7; discussion 107-8.
1994: Wang L H; Tazawa R; Lang A Q; Wu K K
Alternate splicing of human thromboxane synthase mRNA.
Archives of biochemistry and biophysics 1994;315(2):273-8.
1994: Folsom A R; Ma J; Eckfeldt J H; Shahar E; Wu K K
Plasma phospholipid fatty acid composition and factor VII coagulant activity.
Atherosclerosis 1994;111(2):199-207.
1994: Sanduja S K; Tsai A L; Matijevic-Aleksic N; Wu K K
Kinetics of prostacyclin synthesis in PGHS-1-overexpressed endothelial cells.
The American journal of physiology 1994;267(5 Pt 1):C1459-66.
1994: Ruan K H; Milfeld K; Kulmacz R J; Wu K K
Comparison of the construction of a 3-D model for human thromboxane synthase using P450cam and BM-3 as templates: implications for the substrate binding pocket.
Protein engineering 1994;7(11):1345-51.
1994: Conlan M G; Folsom A R; Finch A; Davis C E; Marcucci G; Sorlie P; Wu K K
Antithrombin III: associations with age, race, sex and cardiovascular disease risk factors. The Atherosclerosis Risk in Communities (ARIC) Study Investigators.
Thrombosis and haemostasis 1994;72(4):551-6.
1994: Chen P F; Tsai A L; Wu K K
Cysteine 184 of endothelial nitric oxide synthase is involved in heme coordination and catalytic activity.
The Journal of biological chemistry 1994;269(40):25062-6.
1994: Pereira B; Wu K K; Wang L H
Molecular cloning and characterization of bovine prostacyclin synthase.
Biochemical and biophysical research communications 1994;203(1):59-66.
1994: Tazawa R; Xu X M; Wu K K; Wang L H
Characterization of the genomic structure, chromosomal location and promoter of human prostaglandin H synthase-2 gene.
Biochemical and biophysical research communications 1994;203(1):190-9.
1994: Ruan K H; Li P; Kulmacz R J; Wu K K
Characterization of the structure and membrane interaction of NH2-terminal domain of thromboxane A2 synthase.
The Journal of biological chemistry 1994;269(33):20938-42.
1994: Wu K K; Zoldhelyi P; Willerson J T; Xu X M; Loose-Mitchell D S; Wang L H
Gene therapy for vascular diseases.
Texas Heart Institute journal / from the Texas Heart Institute of St. Luke's Episcopal Hospital, Texas Children's Hospital 1994;21(1):98-103.
1993: Pereira B; Wu K K; Wang L H
Bovine prostacyclin synthase: purification and isolation of partial cDNA.
Biochemical and biophysical research communications 1993;197(3):1041-8.
1993: Folsom A R; Wu K K; Shahar E; Davis C E
Association of hemostatic variables with prevalent cardiovascular disease and asymptomatic carotid artery atherosclerosis. The Atherosclerosis Risk in Communities (ARIC) Study Investigators.
Arteriosclerosis and thrombosis : a journal of vascular biology / American Heart Association 1993;13(12):1829-36.
1993: Zyglewska T; Wu L C; Xu X M; Conlan M G; Wang L H; Wu K K
Quantitative analysis of vascular prostaglandin H synthase mRNA levels by competitive polymerase chain reaction.
The Journal of laboratory and clinical medicine 1993;122(5):542-8.
1993: Conlan M G; Folsom A R; Finch A; Davis C E; Sorlie P; Wu K K
Correlation of plasma protein C levels with cardiovascular risk factors in middle-aged adults: the Atherosclerosis Risk in Communities (ARIC) Study.
Thrombosis and haemostasis 1993;70(5):762-7.
1993: Ruan K H; Wang L H; Wu K K; Kulmacz R J
Amino-terminal topology of thromboxane synthase in the endoplasmic reticulum.
The Journal of biological chemistry 1993;268(26):19483-90.
1993: Conlan M G; Folsom A R; Finch A; Davis C E; Sorlie P; Marcucci G; Wu K K
Associations of factor VIII and von Willebrand factor with age, race, sex, and risk factors for atherosclerosis. The Atherosclerosis Risk in Communities (ARIC) Study.
Thrombosis and haemostasis 1993;70(3):380-5.
1993: Shahar E; Folsom A R; Wu K K; Dennis B H; Shimakawa T; Conlan M G; Davis C E; Williams O D
Associations of fish intake and dietary n-3 polyunsaturated fatty acids with a hypocoagulable profile. The Atherosclerosis Risk in Communities (ARIC) Study.
Arteriosclerosis and thrombosis : a journal of vascular biology / American Heart Association 1993;13(8):1205-12.
1993: Ruan K H; Kulmacz R J; Wilson A; Wu K K
Highly sensitive fluorimetric enzyme immunoassay for prostaglandin H synthase solubilized from cultured cells.
Journal of immunological methods 1993;162(1):23-30.
1993: Xu X M; Ohashi K; Sanduja S K; Ruan K H; Wang L H; Wu K K
Enhanced prostacyclin synthesis in endothelial cells by retrovirus-mediated transfer of prostaglandin H synthase cDNA.
The Journal of clinical investigation 1993;91(4):1843-9.
1993: Nabulsi A A; Folsom A R; White A; Patsch W; Heiss G; Wu K K; Szklo M
Association of hormone-replacement therapy with various cardiovascular risk factors in postmenopausal women. The Atherosclerosis Risk in Communities Study Investigators.
The New England journal of medicine 1993;328(15):1069-75.
1993: Folsom A R; Qamhieh H T; Wing R R; Jeffery R W; Stinson V L; Kuller L H; Wu K K
Impact of weight loss on plasminogen activator inhibitor (PAI-1), factor VII, and other hemostatic factors in moderately overweight adults.
Arteriosclerosis and thrombosis : a journal of vascular biology / American Heart Association 1993;13(2):162-9.
1993: Wang L H; Hajibeigi A; Xu X M; Loose-Mitchell D; Wu K K
Characterization of the promoter of human prostaglandin H synthase-1 gene.
Biochemical and biophysical research communications 1993;190(2):406-11.
1992: Folsom A R; Conlan M G; Davis C E; Wu K K
Relations between hemostasis variables and cardiovascular risk factors in middle-aged adults. Atherosclerosis Risk in Communities (ARIC) Study Investigators.
Annals of epidemiology 1992;2(4):481-94.
1992: Wu K K; Folsom A R; Heiss G; Davis C E; Conlan M G; Barnes R
Association of coagulation factors and inhibitors with carotid artery atherosclerosis. Early results of the Atherosclerosis Risk in Communities (ARIC) Study.
Annals of epidemiology 1992;2(4):471-80.
1992: Zyglewska T; Sanduja R; Ohashi K; Loose-Mitchell D S; Sanduja S K; Wu K K
Inhibition of endothelial cell prostaglandin H synthase gene expression by naproxen.
Biochimica et biophysica acta 1992;1131(1):78-82.
1992: Ohashi K; Ruan K H; Kulmacz R J; Wu K K; Wang L H
Primary structure of human thromboxane synthase determined from the cDNA sequence.
The Journal of biological chemistry 1992;267(2):789-93.
1992: Folsom A R; Wu K K; Conlan M G; Finch A; Davis C E; Marcucci G; Sorlie P D; Szklo M
Distributions of hemostatic variables in blacks and whites: population reference values from the Atherosclerosis Risk in Communities (ARIC) Study.
Ethnicity & disease 1992;2(1):35-46.
1991: Folsom A R; Wu K K; Davis C E; Conlan M G; Sorlie P D; Szklo M
Population correlates of plasma fibrinogen and factor VII, putative cardiovascular risk factors.
Atherosclerosis 1991;91(3):191-205.
1991: Tsai A L; Hsu M J; Patsch W; Wu K K
Regulation of PGI2 activity by serum proteins: serum albumin but not high density lipoprotein is the PGI2 binding and stabilizing protein in human blood.
Biochimica et biophysica acta 1991;1115(2):131-40.
1991: Sanduja S K; Mehta K; Xu X M; Hsu S M; Sanduja R; Wu K K
Differentiation-associated expression of prostaglandin H and thromboxane A synthases in monocytoid leukemia cell lines.
Blood 1991;78(12):3178-85.
1991: Wang L H; Ohashi K; Wu K K
Isolation of partial complementary DNA encoding human thromboxane synthase.
Biochemical and biophysical research communications 1991;177(1):286-91.
1991: Tsai A L; Strobel-Jager E; Wu K K
Conformation of receptor-associated PGI2: an investigation by molecular modeling.
Journal of computer-aided molecular design 1991;5(2):135-48.
1991: Wu K K; Sanduja R; Tsai A L; Ferhanoglu B; Loose-Mitchell D S
Aspirin inhibits interleukin 1-induced prostaglandin H synthase expression in cultured endothelial cells.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(6):2384-7.
1991: Sanduja R; Loose-Mitchell D; Wu K K
Inhibition of de novo synthesis and message expression of prostaglandin H synthase by salicylates.
Advances in prostaglandin, thromboxane, and leukotriene research 1991;21A():149-52.
1991: Tsai A L; Sanduja R; Wu K K
Evidence for two pools of prostaglandin H synthase in human endothelial cells.
Advances in prostaglandin, thromboxane, and leukotriene research 1991;21A():141-4.
1990: Wu K K; Papp A C; Patsch W; Rock R; Eckfeldt J; Sharrett R
ARIC hemostasis study--II. Organizational plan and feasibility study.
Thrombosis and haemostasis 1990;64(4):521-5.
1990: Iso H; Folsom A R; Wu K K; Finch A; Sato S; Munger R G; Shimamoto T; Terao A; Komachi Y
Hemostatic variables in Japanese and Caucasian men. Tissue plasminogen activator, antithrombin III, and protein C and their relations to coronary risk factors.
American journal of epidemiology 1990;132(1):41-6.
1990: Wu K K
Regulation of eicosanoid biosynthesis in endothelial cells: critical role of de novo synthesis of prostaglandin endoperoxide synthase.
Advances in experimental medicine and biology 1990;281():297-301.
1989: Iso H; Folsom A R; Wu K K; Finch A; Munger R G; Sato S; Shimamoto T; Terao A; Komachi Y
Hemostatic variables in Japanese and Caucasian men. Plasma fibrinogen, factor VIIc, factor VIIIc, and von Willebrand factor and their relations to cardiovascular disease risk factors.
American journal of epidemiology 1989;130(5):925-34.
1989: Tsai A L; Hsu M J; Wu K K
Characterization of the interaction between prostacyclin and human serum albumin using a fluorescent analogue, 2,6-dichloro-4-aminophenol iloprost.
Biochimica et biophysica acta 1989;993(1):74-82.
1989: Jones C M; Hall E R; Hester J P; Wu K K
Arachidonic acid metabolites produced by platelet-depleted human blood monocytes: a possible role in thrombogenesis.
American journal of hematology 1989;31(3):145-52.
1989: Pettigrew L C; Grotta J C; Rhoades H M; Wu K K
Effect of thromboxane synthase inhibition on eicosanoid levels and blood flow in ischemic rat brain.
Stroke; a journal of cerebral circulation 1989;20(5):627-32.
1989: Papp A C; Hatzakis H; Bracey A; Wu K K
ARIC hemostasis study--I. Development of a blood collection and processing system suitable for multicenter hemostatic studies.
Thrombosis and haemostasis 1989;61(1):15-9.
1989: Tsai A L; Hsu M J; Vijjeswarapu H; Wu K K
Solubilization of prostacyclin membrane receptors from human platelets.
The Journal of biological chemistry 1989;264(1):61-7.
1989: Wu K K; Lo S S; Papp A C; Vijjeswarapu H N
Stimulation of de novo synthesis of prostaglandin G/H synthase in endothelial cells.
Advances in prostaglandin, thromboxane, and leukotriene research 1989;19():237-41.
1989: Tsai A L; Wu K K
Structure-activity relationship between prostacyclin and its platelet receptor. Correlation of structure change and the platelet activity.
Eicosanoids 1989;2(3):131-43.
1988: Frasier-Scott K; Hatzakis H; Seong D; Jones C M; Wu K K
Influence of natural and recombinant interleukin 2 on endothelial cell arachidonate metabolism. Induction of de novo synthesis of prostaglandin H synthase.
The Journal of clinical investigation 1988;82(6):1877-83.
1988: Wu K K; Hatzakis H; Lo S S; Seong D C; Sanduja S K; Tai H H
Stimulation of de novo synthesis of prostaglandin G/H synthase in human endothelial cells by phorbol ester.
The Journal of biological chemistry 1988;263(35):19043-7.
1988: Hsu S M; Hsu P L; Lo S S; Wu K K
Expression of prostaglandin H synthase (cyclooxygenase) in Hodgkin's mononuclear and Reed-Sternberg cells. Functional resemblance between H-RS cells and histiocytes or interdigitating reticulum cells.
The American journal of pathology 1988;133(1):5-12.
1988: Tsai A L; Manner C E; Rudersdorf T; Wu K K
Quantitation of serum prostacyclin-binding in thrombotic thrombocytopenic purpura.
Thrombosis research 1988;51(6):583-92.
1988: Tsai A L; Vijjeswarapu H; Wu K K
Interaction between platelet receptor and iloprost isomers.
Biochimica et biophysica acta 1988;942(2):220-6.
1988: Wu K K; Frasier-Scott K; Hatzakis H
Endothelial cell function in hemostasis and thrombosis.
Advances in experimental medicine and biology 1988;242():127-33.
1987: Wu K K; Papp A C; Manner C E; Hall E R
Interaction between lymphocytes and platelets in the synthesis of prostacyclin.
The Journal of clinical investigation 1987;79(6):1601-6.
1987: Wu K K; Hatzakis H; Papp A
Cellular and molecular markers of thrombosis.
Hematologic pathology 1987;1(4):249-60.
1986: Pettigrew L C; Wu K K
Platelet function and antiaggregant therapy in ischemic stroke.
Seminars in neurology 1986;6(3):293-8.
1986: Hall E R; Papp A C; Seifert W E; Wu K K
Stimulation of endothelial cell prostacyclin formation by interleukin-2.
Lymphokine research 1986;5(2):87-96.
1985: Papp A C; Hall E R; Wu K K
Binding of prostacyclin by plasma glycoproteins.
Prostaglandins 1985;30(6):1057-68.
1985: Wu K K; Hall E R; Rossi E C; Papp A C
Serum prostacyclin binding defects in thrombotic thrombocytopenic purpura.
The Journal of clinical investigation 1985;75(1):168-74.
1984: Sivarajan M; Hall E R; Wu K K; Rafelson M E; Manner C
Regulation of intracellular arachidonate in normal and stressed endothelial cells.
Biochimica et biophysica acta 1984;795(2):271-6.
1984: Wu K K; Hall E R; Papp A
Modulation of vascular thrombosis by products of arachidonic acid metabolism.
Clinical physiology and biochemistry 1984;2(2-3):84-90.
1982: Wu K K; Hall E R; Papp A
Prostacyclin stabilising factor deficiency in thrombotic thrombocytopenic purpura.
Lancet 1982;1(8269):460-1.

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