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Kenneth Wu

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TOP 3
Marco Campos; Lloyd E Chambless; Maja Barbalic; Eric Boerwinkle; Ashley Buchanan; Aaron R Folsom; Kenneth K Wu; Yang Xiao; Fuli Yu; Jing-fei Dong
Influence of single nucleotide polymorphisms in factor VIII and von Willebrand factor genes on plasma factor VIII activity: the ARIC Study.
Marco Campos; Wei Sun; Fuli Yu; Maja Barbalic; Weihong Tang; Lloyd E Chambless; Kenneth K Wu; Christie Ballantyne; Aaron R Folsom; Eric Boerwinkle; Jing-fei Dong
Genetic determinants of plasma von Willebrand factor antigen levels: a target gene SNP and haplotype analysis of ARIC cohort.
Nena Matijevic; Kenneth K Wu; Nivedita Nidkarni; Gerardo Heiss; Aaron R Folsom
The ARIC carotid MRI study of blood cellular markers: an inverse association of monocyte myeloperoxidase content with peripheral arterial disease.

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2012: Marco Campos; Lloyd E Chambless; Maja Barbalic; Eric Boerwinkle; Ashley Buchanan; Aaron R Folsom; Kenneth K Wu; Yang Xiao; Fuli Yu; Jing-fei Dong
Influence of single nucleotide polymorphisms in factor VIII and von Willebrand factor genes on plasma factor VIII activity: the ARIC Study.
Blood 2012;119(8):1929-34.
2011: Marco Campos; Wei Sun; Fuli Yu; Maja Barbalic; Weihong Tang; Lloyd E Chambless; Kenneth K Wu; Christie Ballantyne; Aaron R Folsom; Eric Boerwinkle; Jing-fei Dong
Genetic determinants of plasma von Willebrand factor antigen levels: a target gene SNP and haplotype analysis of ARIC cohort.
Blood 2011;117(19):5224-30.
2011: Nena Matijevic; Kenneth K Wu; Nivedita Nidkarni; Gerardo Heiss; Aaron R Folsom
The ARIC carotid MRI study of blood cellular markers: an inverse association of monocyte myeloperoxidase content with peripheral arterial disease.
Angiology 2011;62(3):237-44.
2011: N Matijevic; Kenneth K Wu; A G Howard; Bruce A Wasserman; W Y-W Wang; Aaron R Folsom; ALBERT SHARRETT
Association of blood monocyte and platelet markers with carotid artery characteristics: the atherosclerosis risk in communities carotid MRI study.
Cerebrovascular diseases (Basel, Switzerland) 2011;31(6):552-8.
2009: Pei-Feng Chen; Kenneth K Wu
Two synthetic peptides corresponding to the proximal heme-binding domain and CD1 domain of human endothelial nitric-oxide synthase inhibit the oxygenase activity by interacting with CaM.
Archives of biochemistry and biophysics 2009;486(2):132-40.
2009: Jui-Sheng Wu; Wai-Mui Cheung; Yau-Sheng Tsai; Yi-Tong Chen; Wen-Hsuan Fong; Hsin-Da Tsai; Yu-Chang Chen; Jun-Yang Liou; Song-Kun Shyue; Jin-Jer Chen; Y Eugene Chen; Nobuyo Maeda; Kenneth K Wu; Teng-nan Lin
Ligand-activated peroxisome proliferator-activated receptor-gamma protects against ischemic cerebral infarction and neuronal apoptosis by 14-3-3 epsilon upregulation.
Circulation 2009;119(8):1124-34.
2008: Nena Aleksic; Yao-Wei W Wang; Chul Ahn; Harinder S Juneja; Aaron R Folsom; Kenneth K Wu
Assessment of coronary heart disease risk by combined analysis of coagulation factors.
Atherosclerosis 2008;198(2):294-300.
2008: Shun Kohsaka; Kelly A Volcik; Aaron R Folsom; Kenneth K Wu; Christie M Ballantyne; James T Willerson; Eric Boerwinkle
Increased risk of incident stroke associated with the cyclooxygenase 2 (COX-2) G-765C polymorphism in African-Americans: the Atherosclerosis Risk in Communities Study.
Atherosclerosis 2008;196(2):926-30.
2007: Jaou-Chen Huang; W-S A Wun; Jennifer S Goldsby; Karine Egan; garret fitzgerald; Kenneth K Wu
Prostacyclin receptor signaling and early embryo development in the mouse.
Human reproduction (Oxford, England) 2007;22(11):2851-6.
2007: Jun-Yang Liou; Nena Matijevic-Aleksic; Sang Lee; Kenneth K Wu
Prostacyclin inhibits endothelial cell XIAP ubiquitination and degradation.
Journal of cellular physiology 2007;212(3):840-8.
2007: Wu-Guo Deng; Alberto Montero; Kenneth K Wu
Interferon-gamma suppresses cyclooxygenase-2 promoter activity by inhibiting C-Jun and C/EBPbeta binding.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(8):1752-9.
2007: Kenneth K Wu
Differential cyclooxygenase-2 transcriptional control in proliferating versus quiescent fibroblasts.
Prostaglandins & other lipid mediators 2007;83(3):175-81.
2007: Jun-Yang Liou; David P Ellent; Sang Lee; Jennifer S Goldsby; Bor-Sheng Ko; Nena Matijevic; Jaou-Chen Huang; Kenneth K Wu
Cyclooxygenase-2-derived prostaglandin e2 protects mouse embryonic stem cells from apoptosis.
Stem cells (Dayton, Ohio) 2007;25(5):1096-103.
2007: Jun-Yang Liou; Dipak Ghelani; Sam Yeh; Kenneth K Wu
Nonsteroidal anti-inflammatory drugs induce colorectal cancer cell apoptosis by suppressing 14-3-3epsilon.
Cancer research 2007;67(7):3185-91.
2007: Jaou-Chen Huang; W-S A Wun; Jennifer S Goldsby; I C Wun; D Noorhasan; Kenneth K Wu
Stimulation of embryo hatching and implantation by prostacyclin and peroxisome proliferator-activated receptor delta activation: implication in IVF.
Human reproduction (Oxford, England) 2007;22(3):807-14.
2006: Katarzyna A Cieslik; Wu-Guo Deng; Kenneth K Wu
Essential role of C-Rel in nitric-oxide synthase-2 transcriptional activation: time-dependent control by salicylate.
Molecular pharmacology 2006;70(6):2004-14.
2006: Kenneth K Wu
Transcription-based COX-2 inhibition: a therapeutic strategy.
Thrombosis and haemostasis 2006;96(4):417-22.
2006: Wu-Guo Deng; Shao-Tzu Tang; Hui-Ping Tseng; Kenneth K Wu
Melatonin suppresses macrophage cyclooxygenase-2 and inducible nitric oxide synthase expression by inhibiting p52 acetylation and binding.
Blood 2006;108(2):518-24.
2006: Jun-Yang Liou; Sang Lee; Dipak Ghelani; Nena Matijevic-Aleksic; Kenneth K Wu
Protection of endothelial survival by peroxisome proliferator-activated receptor-delta mediated 14-3-3 upregulation.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(7):1481-7.
2006: Teng-nan Lin; Wai-Mui Cheung; Jui-Sheng Wu; Jean-Ju Chen; Heng Lin; Jin-Jer Chen; Jun-Yang Liou; Song-Kun Shyue; Kenneth K Wu
15d-prostaglandin J2 protects brain from ischemia-reperfusion injury.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(3):481-7.
2006: Kenneth K Wu
Analysis of protein-DNA binding by streptavidin-agarose pulldown.
Methods in molecular biology (Clifton, N.J.) 2006;338():281-90.
2005: Kenneth K Wu; Jun-Yang Liou
Cellular and molecular biology of prostacyclin synthase.
Biochemical and biophysical research communications 2005;338(1):45-52.
2005: Jun-Yang Liou; Nena Aleksic; Shu-Fen Chen; Tsai-Jung Han; Song-Kun Shyue; Kenneth K Wu
Mitochondrial localization of cyclooxygenase-2 and calcium-independent phospholipase A2 in human cancer cells: implication in apoptosis resistance.
Experimental cell research 2005;306(1):75-84.
2005: Katarzyna A Cieslik; Ying Zhu; Mikhail Shtivelband; Kenneth K Wu
Inhibition of p90 ribosomal S6 kinase-mediated CCAAT/enhancer-binding protein beta activation and cyclooxygenase-2 expression by salicylate.
The Journal of biological chemistry 2005;280(18):18411-7.
2005: Kenneth K Wu; Jun-Yang Liou; Katarzyna A Cieslik
Transcriptional Control of COX-2 via C/EBPbeta.
Arteriosclerosis, thrombosis, and vascular biology 2005;25(4):679-85.
2005: Kenneth K Wu
Control of cyclooxygenase-2 transcriptional activation by pro-inflammatory mediators.
Prostaglandins, leukotrienes, and essential fatty acids 2005;72(2):89-93.
2005: Kenneth K Wu; Nena Matijevic-Aleksic
Molecular aspects of thrombosis and antithrombotic drugs.
Critical reviews in clinical laboratory sciences 2005;42(3):249-77.
2005: Kenneth K Wu
Novel mechanisms of aspirin pharmacologic actions: a model for studying herbal natural products.
Thrombosis research 2005;117(1-2):61-4; discussion 65-7.
2004: Jaou-Chen Huang; Jennifer S Goldsby; Farinaz Arbab; Ziad Melhem; Nena Aleksic; Kenneth K Wu
Oviduct prostacyclin functions as a paracrine factor to augment the development of embryos.
Human reproduction (Oxford, England) 2004;19(12):2907-12.
2004: Jaou-Chen Huang; W-S A Wun; Jennifer S Goldsby; Nena Matijevic-Aleksic; Kenneth K Wu
Cyclooxygenase-2-derived endogenous prostacyclin enhances mouse embryo hatching.
Human reproduction (Oxford, England) 2004;19(12):2900-6.
2004: Wu-Guo Deng; Ying Zhu; Kenneth K Wu
Role of p300 and PCAF in regulating cyclooxygenase-2 promoter activation by inflammatory mediators.
Blood 2004;103(6):2135-42.
2004: Vahid Afshar-Kharghan; Nena Matijevic-Aleksic; Chul Ahn; Eric Boerwinkle; Kenneth K Wu; José A López
The variable number of tandem repeat polymorphism of platelet glycoprotein Ibalpha and risk of coronary heart disease.
Blood 2004;103(3):963-5.
2003: Pei-Feng Chen; Kenneth K Wu
Structural elements contribute to the calcium/calmodulin dependence on enzyme activation in human endothelial nitric-oxide synthase.
The Journal of biological chemistry 2003;278(52):52392-400.
2003: Wu-Guo Deng; Kenneth K Wu
Regulation of inducible nitric oxide synthase expression by p300 and p50 acetylation.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(12):6581-8.
2003: Jaou-Chen Huang; W-S A Wun; Jennifer S Goldsby; I C Wun; S M Falconi; Kenneth K Wu
Prostacyclin enhances embryo hatching but not sperm motility.
Human reproduction (Oxford, England) 2003;18(12):2582-9.
2003: Wu-Guo Deng; Ying Zhu; Alberto Montero; Kenneth K Wu
Quantitative analysis of binding of transcription factor complex to biotinylated DNA probe by a streptavidin-agarose pulldown assay.
Analytical biochemistry 2003;323(1):12-8.
2003: M I Shtivelband; Harinder Juneja; S Lee; Kenneth K Wu
Aspirin and salicylate inhibit colon cancer medium- and VEGF-induced endothelial tube formation: correlation with suppression of cyclooxygenase-2 expression.
Journal of thrombosis and haemostasis : JTH 2003;1(10):2225-33.
2003: Kenneth K Wu
Soluble thrombomodulin and coronary heart disease.
Current opinion in lipidology 2003;14(4):373-5.
2003: Kenneth K Wu
Control of COX-2 and iNOS gene expressions by aspirin and salicylate.
Thrombosis research 2003;110(5-6):273-6.
2003: Kenneth K Wu
Aspirin and other cyclooxygenase inhibitors: new therapeutic insights.
Seminars in vascular medicine 2003;3(2):107-12.
2003: Kenneth K Wu; Nena Aleksic; Christie M Ballantyne; Chul Ahn; Harinder Juneja; Eric Boerwinkle
Interaction between soluble thrombomodulin and intercellular adhesion molecule-1 in predicting risk of coronary heart disease.
Circulation 2003;107(13):1729-32.
2003: Pei-Feng Chen; Vladimir Berka; Kenneth K Wu
Differential effects of mutations in human endothelial nitric oxide synthase at residues Tyr-357 and Arg-365 on L-arginine hydroxylation and GN-hydroxy-L-arginine oxidation.
Archives of biochemistry and biophysics 2003;411(1):83-92.
2003: Wu-Guo Deng; Ying Zhu; Kenneth K Wu
Up-regulation of p300 binding and p50 acetylation in tumor necrosis factor-alpha-induced cyclooxygenase-2 promoter activation.
The Journal of biological chemistry 2003;278(7):4770-7.
2003: Nena Aleksic; Aaron R Folsom; M Cushman; Susan R Heckbert; M Y Tsai; Kenneth K Wu
Prospective study of the A455V polymorphism in the thrombomodulin gene, plasma thrombomodulin, and incidence of venous thromboembolism: the LITE Study.
Journal of thrombosis and haemostasis : JTH 2003;1(1):88-94.
2002: Katarzyna A Cieslik; Ying Zhu; Kenneth K Wu
Salicylate suppresses macrophage nitric-oxide synthase-2 and cyclo-oxygenase-2 expression by inhibiting CCAAT/enhancer-binding protein-beta binding via a common signaling pathway.
The Journal of biological chemistry 2002;277(51):49304-10.
2002: Jaou-Chen Huang; Farinaz Arbab; Katherine J Tumbusch; Jennifer S Goldsby; Nena Matijevic-Aleksic; Kenneth K Wu
Human fallopian tubes express prostacyclin (PGI) synthase and cyclooxygenases and synthesize abundant PGI.
The Journal of clinical endocrinology and metabolism 2002;87(9):4361-8.
2002: Aaron R Folsom; Nena Aleksic; Diane J Catellier; Harinder Juneja; Kenneth K Wu
C-reactive protein and incident coronary heart disease in the Atherosclerosis Risk In Communities (ARIC) study.
American heart journal 2002;144(2):233-8.
2002: Wu-Guo Deng; Michael A Saunders; Derek W Gilroy; Xue-Zhong He; Howard Yeh; Ying Zhu; Mikhail I Shtivelband; Ke-He Ruan; Kenneth K Wu
Purification and characterization of a cyclooxygenase-2 and angiogenesis suppressing factor produced by human fibroblasts.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(10):1286-8.
2002: Karsten Schroer; Ying Zhu; Michael A Saunders; Wu-Guo Deng; Xiao-Ming Xu; Jutta Meyer-Kirchrath; Kenneth K Wu
Obligatory role of cyclic adenosine monophosphate response element in cyclooxygenase-2 promoter induction and feedback regulation by inflammatory mediators.
Circulation 2002;105(23):2760-5.
2002: Aaron R Folsom; Nena Aleksic; Lu Wang; Mary Cushman; Kenneth K Wu; Richard H White
Protein C, antithrombin, and venous thromboembolism incidence: a prospective population-based study.
Arteriosclerosis, thrombosis, and vascular biology 2002;22(6):1018-22.
2002: Pamela J Schreiner; Kenneth K Wu; M Rene Malinow; Valarie L Stinson; Moyses Szklo; F Javier Nieto; Gerardo Heiss
Hyperhomocyst(e)inemia and hemostatic factors: the atherosclerosis risk in communities study.
Annals of epidemiology 2002;12(4):228-36.
2002: Heng Lin; Teng-nan Lin; Wai-Mui Cheung; Gau-Ming Nian; Ping-Hui Tseng; Shu-Fen Chen; Jean-Ju Chen; Song-Kun Shyue; Jun-Yang Liou; Cheng-Wen Wu; Kenneth K Wu
Cyclooxygenase-1 and bicistronic cyclooxygenase-1/prostacyclin synthase gene transfer protect against ischemic cerebral infarction.
Circulation 2002;105(16):1962-9.
2002: Ying Zhu; Michael A Saunders; Howard Yeh; Wu-Guo Deng; Kenneth K Wu
Dynamic regulation of cyclooxygenase-2 promoter activity by isoforms of CCAAT/enhancer-binding proteins.
The Journal of biological chemistry 2002;277(9):6923-8.
2002: Nena Aleksic; Chul Ahn; Yao-Wei Wang; Harinder Juneja; Aaron R Folsom; Eric Boerwinkle; Kenneth K Wu
Factor XIIIA Val34Leu polymorphism does not predict risk of coronary heart disease: The Atherosclerosis Risk in Communities (ARIC) Study.
Arteriosclerosis, thrombosis, and vascular biology 2002;22(2):348-52.
2001: Wu-Guo Deng; Ke-He Ruan; M Du; Michael A Saunders; Kenneth K Wu
Aspirin and salicylate bind to immunoglobulin heavy chain binding protein (BiP) and inhibit its ATPase activity in human fibroblasts.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(13):2463-70.
2001: Shu-Hui Juan; Tzong-Shyuan Lee; K W Tseng; Jun-Yang Liou; Song-Kun Shyue; Kenneth K Wu; Lee-Young Chau
Adenovirus-mediated heme oxygenase-1 gene transfer inhibits the development of atherosclerosis in apolipoprotein E-deficient mice.
Circulation 2001;104(13):1519-25.
2001: Jun-Yang Liou; Wu-Guo Deng; Derek W Gilroy; Song-Kun Shyue; Kenneth K Wu
Colocalization and interaction of cyclooxygenase-2 with caveolin-1 in human fibroblasts.
The Journal of biological chemistry 2001;276(37):34975-82.
2001: Veikko Salomaa; C Matei; Nena Aleksic; L Sansores-Garcia; Aaron R Folsom; Harinder Juneja; E Park; Kenneth K Wu
Cross-sectional association of soluble thrombomodulin with mild peripheral artery disease; the ARIC study. Atherosclerosis Risk in Communities.
Atherosclerosis 2001;157(2):309-14.
2001: Derek W Gilroy; Michael A Saunders; Kenneth K Wu
COX-2 expression and cell cycle progression in human fibroblasts.
American journal of physiology. Cell physiology 2001;281(1):C188-94.
2001: Michael A Saunders; L Sansores-Garcia; Derek W Gilroy; Kenneth K Wu
Selective suppression of CCAAT/enhancer-binding protein beta binding and cyclooxygenase-2 promoter activity by sodium salicylate in quiescent human fibroblasts.
The Journal of biological chemistry 2001;276(22):18897-904.
2001: Christopher J Logothetis; Kenneth K Wu; LD Finn; Danai D Daliani; W Figg; H Ghaddar; Jordan U Gutterman
Phase I trial of the angiogenesis inhibitor TNP-470 for progressive androgen-independent prostate cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(5):1198-203.
2001: Song-Kun Shyue; May-Jywan Tsai; Jun-Yang Liou; J T Willerson; Kenneth K Wu
Selective augmentation of prostacyclin production by combined prostacyclin synthase and cyclooxygenase-1 gene transfer.
Circulation 2001;103(16):2090-5.
2001: Aaron R Folsom; Nena Aleksic; E Park; Veikko Salomaa; Harinder Juneja; Kenneth K Wu
Prospective study of fibrinolytic factors and incident coronary heart disease: the Atherosclerosis Risk in Communities (ARIC) Study.
Arteriosclerosis, thrombosis, and vascular biology 2001;21(4):611-7.
2001: Aaron R Folsom; Nena Aleksic; Chul Ahn; E Boerwinkle; Kenneth K Wu
Beta-fibrinogen gene -455G/A polymorphism and coronary heart disease incidence: the Atherosclerosis Risk in Communities (ARIC) Study.
Annals of epidemiology 2001;11(3):166-70.
2001: Kenneth K Wu; Nena Aleksic; Chul Ahn; Eric Boerwinkle; Aaron R Folsom; Harinder Juneja
Thrombomodulin Ala455Val polymorphism and risk of coronary heart disease.
Circulation 2001;103(10):1386-9.
2001: Derek W Gilroy; Michael A Saunders; L Sansores-Garcia; Nena Matijevic-Aleksic; Kenneth K Wu
Cell cycle-dependent expression of cyclooxygenase-2 in human fibroblasts.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(2):288-90.
2001: Katarzyna A Cieslik; C S Abrams; Kenneth K Wu
Up-regulation of endothelial nitric-oxide synthase promoter by the phosphatidylinositol 3-kinase gamma /Janus kinase 2/MEK-1-dependent pathway.
The Journal of biological chemistry 2001;276(2):1211-9.
2000: Nena Aleksic; Harinder Juneja; Aaron R Folsom; Chul Ahn; Eric Boerwinkle; Lloyd E Chambless; Kenneth K Wu
Platelet Pl(A2) allele and incidence of coronary heart disease: results from the Atherosclerosis Risk In Communities (ARIC) Study.
Circulation 2000;102(16):1901-5.
2000: Jun-Yang Liou; Song-Kun Shyue; May-Jywan Tsai; C L Chung; K Y Chu; Kenneth K Wu
Colocalization of prostacyclin synthase with prostaglandin H synthase-1 (PGHS-1) but not phorbol ester-induced PGHS-2 in cultured endothelial cells.
The Journal of biological chemistry 2000;275(20):15314-20.
2000: Pei-Feng Chen; Kenneth K Wu
Characterization of the roles of the 594-645 region in human endothelial nitric-oxide synthase in regulating calmodulin binding and electron transfer.
The Journal of biological chemistry 2000;275(17):13155-63.
2000: Aaron R Folsom; Kenneth K Wu; M Rasmussen; Lloyd E Chambless; Nena Aleksic; F Javier Nieto
Determinants of population changes in fibrinogen and factor VII over 6 years: the Atherosclerosis Risk in Communities (ARIC) Study.
Arteriosclerosis, thrombosis, and vascular biology 2000;20(2):601-6.
1999: Katarzyna A Cieslik; C M Lee; JL Tang; Kenneth K Wu
Transcriptional regulation of endothelial nitric-oxide synthase by an interaction between casein kinase 2 and protein phosphatase 2A.
The Journal of biological chemistry 1999;274(49):34669-75.
1999: Aaron R Folsom; Wayne D Rosamond; Eyal Shahar; Lawton S Cooper; Nena Aleksic; F Javier Nieto; ML Rasmussen; Kenneth K Wu
Prospective study of markers of hemostatic function with risk of ischemic stroke. The Atherosclerosis Risk in Communities (ARIC) Study Investigators.
Circulation 1999;100(7):736-42.
1999: Veikko Salomaa; C Matei; Nena Aleksic; L Sansores-Garcia; Aaron R Folsom; Harinder Juneja; Lloyd E Chambless; Kenneth K Wu
Soluble thrombomodulin as a predictor of incident coronary heart disease and symptomless carotid artery atherosclerosis in the Atherosclerosis Risk in Communities (ARIC) Study: a case-cohort study.
Lancet 1999;353(9166):1729-34.
1999: X M Xu; L Sansores-Garcia; X M Chen; Nena Matijevic-Aleksic; M Du; Kenneth K Wu
Suppression of inducible cyclooxygenase 2 gene transcription by aspirin and sodium salicylate.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(9):5292-7.
1999: Kenneth K Wu; Nena Aleksic
Platelet glycoprotein polymorphism and risk for coronary heart disease.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 1999;10 Suppl 1():S63-5.
1998: H M Ghaddar; Aaron R Folsom; Nena Aleksic; L B Hearne; Lloyd E Chambless; James Morrissey; Kenneth K Wu
Correlation of factor VIIa values with factor VII gene polymorphism, fasting and postprandial triglyceride levels, and subclinical carotid atherosclerosis.
Circulation 1998;98(25):2815-21.
1998: Pei-Feng Chen; Vladimir Berka; Ah-Lim Tsai; Kenneth K Wu
Effects of Asp-369 and Arg-372 mutations on heme environment and function in human endothelial nitric-oxide synthase.
The Journal of biological chemistry 1998;273(51):34164-70.
1998: Aaron R Folsom; James M Peacock; F Javier Nieto; Wayne D Rosamond; M L Eigenbrodt; Clarence E Davis; Kenneth K Wu
Plasma fibrinogen and incident hypertension in the Atherosclerosis Risk in Communities (ARIC) Study.
Journal of hypertension 1998;16(11):1579-83.
1998: M Du; L Sansores-Garcia; Z Zu; Kenneth K Wu
Cloning and expression analysis of a novel salicylate suppressible gene, Hs-CUL-3, a member of cullin/Cdc53 family.
The Journal of biological chemistry 1998;273(38):24289-92.
1998: Katarzyna A Cieslik; A Zembowicz; JL Tang; Kenneth K Wu
Transcriptional regulation of endothelial nitric-oxide synthase by lysophosphatidylcholine.
The Journal of biological chemistry 1998;273(24):14885-90.
1998: Kenneth K Wu
Biochemical pharmacology of nonsteroidal anti-inflammatory drugs.
Biochemical pharmacology 1998;55(5):543-7.
1998: Jaou-Chen Huang; D Y Liu; S Yadollahi; Kenneth K Wu; M Yusoff Dawood
Interleukin-1 beta induces cyclooxygenase-2 gene expression in cultured endometrial stromal cells.
The Journal of clinical endocrinology and metabolism 1998;83(2):538-41.
1997: Kenneth K Wu
Genetic markers: genes involved in thrombosis.
Journal of cardiovascular risk 1997;4(5-6):347-52.
1997: Aaron R Folsom; Kenneth K Wu; Wayne D Rosamond; ALBERT SHARRETT; Lloyd E Chambless
Prospective study of hemostatic factors and incidence of coronary heart disease: the Atherosclerosis Risk in Communities (ARIC) Study.
Circulation 1997;96(4):1102-8.
1997: X M Xu; JL Tang; X Chen; Lee-Ho Wang; Kenneth K Wu
Involvement of two Sp1 elements in basal endothelial prostaglandin H synthase-1 promoter activity.
The Journal of biological chemistry 1997;272(11):6943-50.
1997: Pei-Feng Chen; Ah-Lim Tsai; Vladimir Berka; Kenneth K Wu
Mutation of Glu-361 in human endothelial nitric-oxide synthase selectively abolishes L-arginine binding without perturbing the behavior of heme and other redox centers.
The Journal of biological chemistry 1997;272(10):6114-8.
1997: Song-Kun Shyue; Ke-He Ruan; Lee-Ho Wang; Kenneth K Wu
Prostacyclin synthase active sites. Identification by molecular modeling-guided site-directed mutagenesis.
The Journal of biological chemistry 1997;272(6):3657-62.
1997: Kenneth K Wu
Regulation of prostaglandin H synthase-1 gene expression.
Advances in experimental medicine and biology 1997;400A():121-6.
1997: James S Pankow; Aaron R Folsom; M A Province; D C Rao; John H Eckfeldt; Gerardo Heiss; E Shahar; Kenneth K Wu
Family history of coronary heart disease and hemostatic variables in middle-aged adults. Atherosclerosis Risk in Communities Investigators and Family Heart Study Research Group.
Thrombosis and haemostasis 1997;77(1):87-93.
1996: R Tazawa; Eric Green; Kazuteru Ohashi; Kenneth K Wu; Lee-Ho Wang
Characterization of the complete genomic structure of human thromboxane synthase gene and functional analysis of its promoter.
Archives of biochemistry and biophysics 1996;334(2):349-56.
1996: Kenneth K Wu
Endothelial prostaglandin and nitric oxide synthesis in atherogenesis and thrombosis.
Journal of the Formosan Medical Association = Taiwan yi zhi 1996;95(9):661-6.
1996: Kenneth K Wu
Cyclooxygenase 2 induction: molecular mechanism and pathophysiologic roles.
The Journal of laboratory and clinical medicine 1996;128(3):242-5.
1996: Lee-Ho Wang; N Matijevic-Aleksic; P Y Hsu; Ke-He Ruan; Kenneth K Wu; Richard J Kulmacz
Identification of thromboxane A2 synthase active site residues by molecular modeling-guided site-directed mutagenesis.
The Journal of biological chemistry 1996;271(33):19970-5.
1996: Pei-Feng Chen; Ah-Lim Tsai; Vladimir Berka; Kenneth K Wu
Endothelial nitric-oxide synthase. Evidence for bidomain structure and successful reconstitution of catalytic activity from two separate domains generated by a baculovirus expression system.
The Journal of biological chemistry 1996;271(24):14631-5.
1996: Eyal Shahar; Aaron R Folsom; V V Salomaa; V L Stinson; Paul G McGovern; T Shimakawa; Lloyd E Chambless; Kenneth K Wu
Relation of hormone-replacement therapy to measures of plasma fibrinolytic activity. Atherosclerosis Risk in Communities (ARIC) Study Investigators.
Circulation 1996;93(11):1970-5.
1996: X M Xu; J L Tang; A Hajibeigi; D S Loose-Mitchell; Kenneth K Wu
Transcriptional regulation of endothelial constitutive PGHS-1 expression by phorbol ester.
The American journal of physiology 1996;270(1 Pt 1):C259-64.
1996: Kenneth K Wu; Perumal Thiagarajan
Role of endothelium in thrombosis and hemostasis.
Annual review of medicine 1996;47():315-31.
1996: Pierre Zoldhelyi; J McNatt; X M Xu; D Loose-Mitchell; Robert S Meidell; F J Clubb; L Maximilian Buja; James T Willerson; Kenneth K Wu
Prevention of arterial thrombosis by adenovirus-mediated transfer of cyclooxygenase gene.
Circulation 1996;93(1):10-7.
1996: N Matijevic-Aleksic; P McPhedran; Kenneth K Wu
Bleeding disorder due to platelet prostaglandin H synthase-1 (PGHS-1) deficiency.
British journal of haematology 1996;92(1):212-7.
1995: N Matijevic-Aleksic; S K Sanduja; Lee-Ho Wang; Kenneth K Wu
Differential expression of thromboxane A synthase and prostaglandin H synthase in megakaryocytic cell line.
Biochimica et biophysica acta 1995;1269(2):167-75.
1995: Pei-Feng Chen; Ah-Lim Tsai; Kenneth K Wu
Cysteine 99 of endothelial nitric oxide synthase (NOS-III) is critical for tetrahydrobiopterin-dependent NOS-III stability and activity.
Biochemical and biophysical research communications 1995;215(3):1119-29.
1995: A Zembowicz; S L Jones; Kenneth K Wu
Induction of cyclooxygenase-2 in human umbilical vein endothelial cells by lysophosphatidylcholine.
The Journal of clinical investigation 1995;96(3):1688-92.
1995: J L Tang; A Zembowicz; X M Xu; Kenneth K Wu
Role of Sp1 in transcriptional activation of human nitric oxide synthase type III gene.
Biochemical and biophysical research communications 1995;213(2):673-80.
1995: A Zembowicz; J L Tang; Kenneth K Wu
Transcriptional induction of endothelial nitric oxide synthase type III by lysophosphatidylcholine.
The Journal of biological chemistry 1995;270(28):17006-10.
1995: N D Nguyen; H Ghaddar; V Stinson; Lloyd E Chambless; Kenneth K Wu
ARIC hemostasis study--IV. Intraindividual variability and reliability of hemostatic factors. The Atherosclerosis Risk in Communities (ARIC).
Thrombosis and haemostasis 1995;73(2):256-60.
1995: V Salomaa; V Stinson; J D Kark; A R Folsom; Clarence E Davis; Kenneth K Wu
Association of fibrinolytic parameters with early atherosclerosis. The ARIC Study. Atherosclerosis Risk in Communities Study.
Circulation 1995;91(2):284-90.
1995: Kenneth K Wu; Pierre Zoldhelyi; James T Willerson; Robert S Meidell; J McNatt; X M Xu
Restoration of prostacyclin synthesis by transfer of prostaglandin H synthase cDNA.
Advances in prostaglandin, thromboxane, and leukotriene research 1995;23():377-9.
1995: X M Xu; A Hajibeige; R Tazawa; D Loose-Mitchell; Lee-Ho Wang; Kenneth K Wu
Characterization of human prostaglandin H synthase genes.
Advances in prostaglandin, thromboxane, and leukotriene research 1995;23():105-7.
1995: Kenneth K Wu
Molecular regulation and augmentation of prostacyclin biosynthesis.
Agents and actions. Supplements 1995;45():11-7.
1995: James T Willerson; Pierre Zoldhelyi; Robert S Meidell; J McNatt; X M Xu; Kenneth K Wu
Gene therapy to restore prostacyclin presence to injured endothelium.
Transactions of the American Clinical and Climatological Association 1995;106():100-7; discussion 107-8.
1994: Lee-Ho Wang; R Tazawa; A Q Lang; Kenneth K Wu
Alternate splicing of human thromboxane synthase mRNA.
Archives of biochemistry and biophysics 1994;315(2):273-8.
1994: Aaron R Folsom; J Ma; John H Eckfeldt; Eyal Shahar; Kenneth K Wu
Plasma phospholipid fatty acid composition and factor VII coagulant activity.
Atherosclerosis 1994;111(2):199-207.
1994: S K Sanduja; Ah-Lim Tsai; N Matijevic-Aleksic; Kenneth K Wu
Kinetics of prostacyclin synthesis in PGHS-1-overexpressed endothelial cells.
The American journal of physiology 1994;267(5 Pt 1):C1459-66.
1994: Ke-He Ruan; K Milfeld; Richard J Kulmacz; Kenneth K Wu
Comparison of the construction of a 3-D model for human thromboxane synthase using P450cam and BM-3 as templates: implications for the substrate binding pocket.
Protein engineering 1994;7(11):1345-51.
1994: Pei-Feng Chen; Ah-Lim Tsai; Kenneth K Wu
Cysteine 184 of endothelial nitric oxide synthase is involved in heme coordination and catalytic activity.
The Journal of biological chemistry 1994;269(40):25062-6.
1994: M G Conlan; Aaron R Folsom; A Finch; C E Davis; G Marcucci; Paul D Sorlie; Kenneth K Wu
Antithrombin III: associations with age, race, sex and cardiovascular disease risk factors. The Atherosclerosis Risk in Communities (ARIC) Study Investigators.
Thrombosis and haemostasis 1994;72(4):551-6.
1994: B Pereira; Kenneth K Wu; Lee-Ho Wang
Molecular cloning and characterization of bovine prostacyclin synthase.
Biochemical and biophysical research communications 1994;203(1):59-66.
1994: R Tazawa; X M Xu; Kenneth K Wu; Lee-Ho Wang
Characterization of the genomic structure, chromosomal location and promoter of human prostaglandin H synthase-2 gene.
Biochemical and biophysical research communications 1994;203(1):190-9.
1994: Ke-He Ruan; P Li; Richard J Kulmacz; Kenneth K Wu
Characterization of the structure and membrane interaction of NH2-terminal domain of thromboxane A2 synthase.
The Journal of biological chemistry 1994;269(33):20938-42.
1994: Kenneth K Wu; Pierre Zoldhelyi; James T Willerson; X M Xu; D S Loose-Mitchell; L H Wang
Gene therapy for vascular diseases.
Texas Heart Institute journal / from the Texas Heart Institute of St. Luke's Episcopal Hospital, Texas Children's Hospital 1994;21(1):98-103.
1993: B Pereira; Kenneth K Wu; Lee-Ho Wang
Bovine prostacyclin synthase: purification and isolation of partial cDNA.
Biochemical and biophysical research communications 1993;197(3):1041-8.
1993: Aaron R Folsom; Kenneth K Wu; Eyal Shahar; Clarence E Davis
Association of hemostatic variables with prevalent cardiovascular disease and asymptomatic carotid artery atherosclerosis. The Atherosclerosis Risk in Communities (ARIC) Study Investigators.
Arteriosclerosis and thrombosis : a journal of vascular biology / American Heart Association 1993;13(12):1829-36.
1993: M G Conlan; Aaron R Folsom; A Finch; C E Davis; Paul D Sorlie; Kenneth K Wu
Correlation of plasma protein C levels with cardiovascular risk factors in middle-aged adults: the Atherosclerosis Risk in Communities (ARIC) Study.
Thrombosis and haemostasis 1993;70(5):762-7.
1993: T Zyglewska; L C Wu; X M Xu; M G Conlan; L H Wang; Kenneth K Wu
Quantitative analysis of vascular prostaglandin H synthase mRNA levels by competitive polymerase chain reaction.
The Journal of laboratory and clinical medicine 1993;122(5):542-8.
1993: Ke-He Ruan; Lee-Ho Wang; Kenneth K Wu; Richard J Kulmacz
Amino-terminal topology of thromboxane synthase in the endoplasmic reticulum.
The Journal of biological chemistry 1993;268(26):19483-90.
1993: M G Conlan; Aaron R Folsom; A Finch; C E Davis; Paul D Sorlie; G Marcucci; Kenneth K Wu
Associations of factor VIII and von Willebrand factor with age, race, sex, and risk factors for atherosclerosis. The Atherosclerosis Risk in Communities (ARIC) Study.
Thrombosis and haemostasis 1993;70(3):380-5.
1993: Eyal Shahar; Aaron R Folsom; Kenneth K Wu; Barbara Dennis; T Shimakawa; M G Conlan; Clarence E Davis; Dale O Williams
Associations of fish intake and dietary n-3 polyunsaturated fatty acids with a hypocoagulable profile. The Atherosclerosis Risk in Communities (ARIC) Study.
Arteriosclerosis and thrombosis : a journal of vascular biology / American Heart Association 1993;13(8):1205-12.
1993: Ke-He Ruan; Richard J Kulmacz; A Wilson; Kenneth K Wu
Highly sensitive fluorimetric enzyme immunoassay for prostaglandin H synthase solubilized from cultured cells.
Journal of immunological methods 1993;162(1):23-30.
1993: A A Nabulsi; Aaron R Folsom; A White; W Patsch; Gerardo Heiss; Kenneth K Wu; Moyses Szklo
Association of hormone-replacement therapy with various cardiovascular risk factors in postmenopausal women. The Atherosclerosis Risk in Communities Study Investigators.
The New England journal of medicine 1993;328(15):1069-75.
1993: X M Xu; Kazuteru Ohashi; S K Sanduja; Ke-He Ruan; Lee-Ho Wang; Kenneth K Wu
Enhanced prostacyclin synthesis in endothelial cells by retrovirus-mediated transfer of prostaglandin H synthase cDNA.
The Journal of clinical investigation 1993;91(4):1843-9.
1993: Aaron R Folsom; H T Qamhieh; Rena R Wing; R W Jeffery; V L Stinson; L H Kuller; Kenneth K Wu
Impact of weight loss on plasminogen activator inhibitor (PAI-1), factor VII, and other hemostatic factors in moderately overweight adults.
Arteriosclerosis and thrombosis : a journal of vascular biology / American Heart Association 1993;13(2):162-9.
1993: Lee-Ho Wang; A Hajibeigi; X M Xu; D Loose-Mitchell; Kenneth K Wu
Characterization of the promoter of human prostaglandin H synthase-1 gene.
Biochemical and biophysical research communications 1993;190(2):406-11.
1992: Aaron R Folsom; M G Conlan; Clarence E Davis; Kenneth K Wu
Relations between hemostasis variables and cardiovascular risk factors in middle-aged adults. Atherosclerosis Risk in Communities (ARIC) Study Investigators.
Annals of epidemiology 1992;2(4):481-94.
1992: Kenneth K Wu; Aaron R Folsom; Gerardo Heiss; C E Davis; M G Conlan; R Barnes
Association of coagulation factors and inhibitors with carotid artery atherosclerosis. Early results of the Atherosclerosis Risk in Communities (ARIC) Study.
Annals of epidemiology 1992;2(4):471-80.
1992: T Zyglewska; R Sanduja; Kazuteru Ohashi; D S Loose-Mitchell; S K Sanduja; Kenneth K Wu
Inhibition of endothelial cell prostaglandin H synthase gene expression by naproxen.
Biochimica et biophysica acta 1992;1131(1):78-82.
1992: Kazuteru Ohashi; Ke-He Ruan; Richard J Kulmacz; Kenneth K Wu; Lee-Ho Wang
Primary structure of human thromboxane synthase determined from the cDNA sequence.
The Journal of biological chemistry 1992;267(2):789-93.
1992: Aaron R Folsom; Kenneth K Wu; M G Conlan; A Finch; Clarence E Davis; G Marcucci; Paul D Sorlie; Moyses Szklo
Distributions of hemostatic variables in blacks and whites: population reference values from the Atherosclerosis Risk in Communities (ARIC) Study.
Ethnicity & disease 1992;2(1):35-46.
1991: S K Sanduja; K Mehta; X M Xu; S M Hsu; R Sanduja; Kenneth K Wu
Differentiation-associated expression of prostaglandin H and thromboxane A synthases in monocytoid leukemia cell lines.
Blood 1991;78(12):3178-85.
1991: Ah-Lim Tsai; M J Hsu; W Patsch; Kenneth K Wu
Regulation of PGI2 activity by serum proteins: serum albumin but not high density lipoprotein is the PGI2 binding and stabilizing protein in human blood.
Biochimica et biophysica acta 1991;1115(2):131-40.
1991: Aaron R Folsom; Kenneth K Wu; Clarence E Davis; M G Conlan; Paul D Sorlie; Moyses Szklo
Population correlates of plasma fibrinogen and factor VII, putative cardiovascular risk factors.
Atherosclerosis 1991;91(3):191-205.
1991: Lee-Ho Wang; Kazuteru Ohashi; Kenneth K Wu
Isolation of partial complementary DNA encoding human thromboxane synthase.
Biochemical and biophysical research communications 1991;177(1):286-91.
1991: Ah-Lim Tsai; E Strobel-Jager; Kenneth K Wu
Conformation of receptor-associated PGI2: an investigation by molecular modeling.
Journal of computer-aided molecular design 1991;5(2):135-48.
1991: Kenneth K Wu; R Sanduja; Ah-Lim Tsai; B Ferhanoglu; D S Loose-Mitchell
Aspirin inhibits interleukin 1-induced prostaglandin H synthase expression in cultured endothelial cells.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(6):2384-7.
1991: R Sanduja; D Loose-Mitchell; Kenneth K Wu
Inhibition of de novo synthesis and message expression of prostaglandin H synthase by salicylates.
Advances in prostaglandin, thromboxane, and leukotriene research 1991;21A():149-52.
1991: Ah-Lim Tsai; R Sanduja; Kenneth K Wu
Evidence for two pools of prostaglandin H synthase in human endothelial cells.
Advances in prostaglandin, thromboxane, and leukotriene research 1991;21A():141-4.
1990: Kenneth K Wu; A C Papp; W Patsch; R Rock; J Eckfeldt; ALBERT SHARRETT
ARIC hemostasis study--II. Organizational plan and feasibility study.
Thrombosis and haemostasis 1990;64(4):521-5.
1990: Hiroyasu Iso; Aaron R Folsom; Kenneth K Wu; A Finch; S Sato; Ronald G Munger; T Shimamoto; A Terao; Yoshio Komachi
Hemostatic variables in Japanese and Caucasian men. Tissue plasminogen activator, antithrombin III, and protein C and their relations to coronary risk factors.
American journal of epidemiology 1990;132(1):41-6.
1990: Kenneth K Wu
Regulation of eicosanoid biosynthesis in endothelial cells: critical role of de novo synthesis of prostaglandin endoperoxide synthase.
Advances in experimental medicine and biology 1990;281():297-301.
1989: Hiroyasu Iso; Aaron R Folsom; Kenneth K Wu; A Finch; Ronald G Munger; S Sato; T Shimamoto; A Terao; Yoshio Komachi
Hemostatic variables in Japanese and Caucasian men. Plasma fibrinogen, factor VIIc, factor VIIIc, and von Willebrand factor and their relations to cardiovascular disease risk factors.
American journal of epidemiology 1989;130(5):925-34.
1989: Ah-Lim Tsai; M J Hsu; Kenneth K Wu
Characterization of the interaction between prostacyclin and human serum albumin using a fluorescent analogue, 2,6-dichloro-4-aminophenol iloprost.
Biochimica et biophysica acta 1989;993(1):74-82.
1989: C M Jones; E R Hall; Jeane Hester; Kenneth K Wu
Arachidonic acid metabolites produced by platelet-depleted human blood monocytes: a possible role in thrombogenesis.
American journal of hematology 1989;31(3):145-52.
1989: L C Pettigrew; James C Grotta; H M Rhoades; Kenneth K Wu
Effect of thromboxane synthase inhibition on eicosanoid levels and blood flow in ischemic rat brain.
Stroke; a journal of cerebral circulation 1989;20(5):627-32.
1989: A C Papp; H Hatzakis; A Bracey; Kenneth K Wu
ARIC hemostasis study--I. Development of a blood collection and processing system suitable for multicenter hemostatic studies.
Thrombosis and haemostasis 1989;61(1):15-9.
1989: Ah-Lim Tsai; M J Hsu; H Vijjeswarapu; Kenneth K Wu
Solubilization of prostacyclin membrane receptors from human platelets.
The Journal of biological chemistry 1989;264(1):61-7.
1989: Kenneth K Wu; S S Lo; A C Papp; H N Vijjeswarapu
Stimulation of de novo synthesis of prostaglandin G/H synthase in endothelial cells.
Advances in prostaglandin, thromboxane, and leukotriene research 1989;19():237-41.
1989: Ah-Lim Tsai; Kenneth K Wu
Structure-activity relationship between prostacyclin and its platelet receptor. Correlation of structure change and the platelet activity.
Eicosanoids 1989;2(3):131-43.
1988: Kenneth K Wu; H Hatzakis; S S Lo; D C Seong; S K Sanduja; H H Tai
Stimulation of de novo synthesis of prostaglandin G/H synthase in human endothelial cells by phorbol ester.
The Journal of biological chemistry 1988;263(35):19043-7.
1988: K Frasier-Scott; H Hatzakis; D Seong; C M Jones; Kenneth K Wu
Influence of natural and recombinant interleukin 2 on endothelial cell arachidonate metabolism. Induction of de novo synthesis of prostaglandin H synthase.
The Journal of clinical investigation 1988;82(6):1877-83.
1988: S M Hsu; P L Hsu; S S Lo; Kenneth K Wu
Expression of prostaglandin H synthase (cyclooxygenase) in Hodgkin's mononuclear and Reed-Sternberg cells. Functional resemblance between H-RS cells and histiocytes or interdigitating reticulum cells.
The American journal of pathology 1988;133(1):5-12.
1988: Ah-Lim Tsai; C E Manner; T Rudersdorf; Kenneth K Wu
Quantitation of serum prostacyclin-binding in thrombotic thrombocytopenic purpura.
Thrombosis research 1988;51(6):583-92.
1988: Ah-Lim Tsai; H Vijjeswarapu; Kenneth K Wu
Interaction between platelet receptor and iloprost isomers.
Biochimica et biophysica acta 1988;942(2):220-6.
1988: Kenneth K Wu; K Frasier-Scott; H Hatzakis
Endothelial cell function in hemostasis and thrombosis.
Advances in experimental medicine and biology 1988;242():127-33.
1987: Kenneth K Wu; A C Papp; C E Manner; E R Hall
Interaction between lymphocytes and platelets in the synthesis of prostacyclin.
The Journal of clinical investigation 1987;79(6):1601-6.
1987: Kenneth K Wu; H Hatzakis; A Papp
Cellular and molecular markers of thrombosis.
Hematologic pathology 1987;1(4):249-60.
1986: L C Pettigrew; Kenneth K Wu
Platelet function and antiaggregant therapy in ischemic stroke.
Seminars in neurology 1986;6(3):293-8.
1986: E R Hall; A C Papp; W E Seifert; Kenneth K Wu
Stimulation of endothelial cell prostacyclin formation by interleukin-2.
Lymphokine research 1986;5(2):87-96.
1985: A C Papp; E R Hall; Kenneth K Wu
Binding of prostacyclin by plasma glycoproteins.
Prostaglandins 1985;30(6):1057-68.
1985: Kenneth K Wu; E R Hall; E C Rossi; A C Papp
Serum prostacyclin binding defects in thrombotic thrombocytopenic purpura.
The Journal of clinical investigation 1985;75(1):168-74.
1984: M Sivarajan; E R Hall; Kenneth K Wu; M E Rafelson; C Manner
Regulation of intracellular arachidonate in normal and stressed endothelial cells.
Biochimica et biophysica acta 1984;795(2):271-6.
1984: Kenneth K Wu; E R Hall; A Papp
Modulation of vascular thrombosis by products of arachidonic acid metabolism.
Clinical physiology and biochemistry 1984;2(2-3):84-90.
1982: Kenneth K Wu; E R Hall; A Papp
Prostacyclin stabilising factor deficiency in thrombotic thrombocytopenic purpura.
Lancet 1982;1(8269):460-1.