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Shwu-Yuan Wu

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Bhaskar Ponugoti; Dong-Hyun Kim; Zhen Xiao; Zachary Smith; Ji Miao; Mengwei Zang; Shwu-Yuan Wu; Cheng-Ming Chiang; Timothy D Veenstra; Jongsook Kim Kemper
SIRT1 deacetylates and inhibits SREBP-1C activity in regulation of hepatic lipid metabolism.
Jongsook Kim Kemper; Zhen Xiao; Bhaskar Ponugoti; Ji Miao; Sungsoon Fang; Deepthi Kanamaluru; Stephanie Tsang; Shwu-Yuan Wu; Cheng-Ming Chiang; Timothy D Veenstra
FXR acetylation is normally dynamically regulated by p300 and SIRT1 but constitutively elevated in metabolic disease states.
Jianqi Yang; Xiaoying Kong; Maria Emilia S Martins-Santos; Gabriela Aleman; Ernestine Chaco; George E Liu; Shwu-Yuan Wu; David Samols; Parvin Hakimi; Cheng-Ming Chiang; Richard W Hanson
Activation of SIRT1 by resveratrol represses transcription of the gene for the cytosolic form of phosphoenolpyruvate carboxykinase (GTP) by deacetylating hepatic nuclear factor 4alpha.

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All Publications

2010: Bhaskar Ponugoti; Dong-Hyun Kim; Zhen Xiao; Zachary Smith; Ji Miao; Mengwei Zang; Shwu-Yuan Wu; Cheng-Ming Chiang; Timothy D Veenstra; Jongsook Kim Kemper
SIRT1 deacetylates and inhibits SREBP-1C activity in regulation of hepatic lipid metabolism.
The Journal of biological chemistry 2010;285(44):33959-70.
2009: Jongsook Kim Kemper; Zhen Xiao; Bhaskar Ponugoti; Ji Miao; Sungsoon Fang; Deepthi Kanamaluru; Stephanie Tsang; Shwu-Yuan Wu; Cheng-Ming Chiang; Timothy D Veenstra
FXR acetylation is normally dynamically regulated by p300 and SIRT1 but constitutively elevated in metabolic disease states.
Cell metabolism 2009;10(5):392-404.
2009: Jianqi Yang; Xiaoying Kong; Maria Emilia S Martins-Santos; Gabriela Aleman; Ernestine Chaco; George E Liu; Shwu-Yuan Wu; David Samols; Parvin Hakimi; Cheng-Ming Chiang; Richard W Hanson
Activation of SIRT1 by resveratrol represses transcription of the gene for the cytosolic form of phosphoenolpyruvate carboxykinase (GTP) by deacetylating hepatic nuclear factor 4alpha.
The Journal of biological chemistry 2009;284(40):27042-53.
2008: Sungsoon Fang; Stephanie Tsang; Ryan Jones; Bhaskar Ponugoti; Hyeryoung Yoon; Shwu-Yuan Wu; Cheng-Ming Chiang; Timothy M Willson; Jongsook Kim Kemper
The p300 acetylase is critical for ligand-activated farnesoid X receptor (FXR) induction of SHP.
The Journal of biological chemistry 2008;283(50):35086-95.
2007: Shwu-Yuan Wu; Cheng-Ming Chiang
The double bromodomain-containing chromatin adaptor Brd4 and transcriptional regulation.
The Journal of biological chemistry 2007;282(18):13141-5.
2006: Shwu-Yuan Wu; A-Young Lee; Samuel Y Hou; Jongsook Kim Kemper; Hediye Erdjument-Bromage; Paul Tempst; Cheng-Ming Chiang
Brd4 links chromatin targeting to HPV transcriptional silencing.
Genes & development 2006;20(17):2383-96.
2006: Young Kyeung Kim; Cyril F Bourgeois; Richard Pearson; Mudit Tyagi; Michelle Joanne West; Julian Wong; Shwu-Yuan Wu; Cheng-Ming Chiang; Jonathan Karn
Recruitment of TFIIH to the HIV LTR is a rate-limiting step in the emergence of HIV from latency.
The EMBO journal 2006;25(15):3596-604.
2004: Kaushik Chakravarty; Shwu-Yuan Wu; Cheng-Ming Chiang; David Samols; Richard W Hanson
SREBP-1c and Sp1 interact to regulate transcription of the gene for phosphoenolpyruvate carboxykinase (GTP) in the liver.
The Journal of biological chemistry 2004;279(15):15385-95.
2003: Shwu-Yuan Wu; Tianyuan Zhou; Cheng-Ming Chiang
Human mediator enhances activator-facilitated recruitment of RNA polymerase II and promoter recognition by TATA-binding protein (TBP) independently of TBP-associated factors.
Molecular and cellular biology 2003;23(17):6229-42.
2002: Samuel Y Hou; Shwu-Yuan Wu; Cheng-Ming Chiang
Transcriptional activity among high and low risk human papillomavirus E2 proteins correlates with E2 DNA binding.
The Journal of biological chemistry 2002;277(47):45619-29.
2002: Shwu-Yuan Wu; Cheng-Ming Chiang
Expression and purification of epitope-tagged multisubunit protein complexes from mammalian cells.
Current protocols in molecular biology / edited by Frederick M. Ausubel ... [et al.] 2002;Chapter 16():Unit 16.13.
2001: Shwu-Yuan Wu; Cheng-Ming Chiang
TATA-binding protein-associated factors enhance the recruitment of RNA polymerase II by transcriptional activators.
The Journal of biological chemistry 2001;276(36):34235-43.
2000: Samuel Y Hou; Shwu-Yuan Wu; T Zhou; Mary C Thomas; Cheng-Ming Chiang
Alleviation of human papillomavirus E2-mediated transcriptional repression via formation of a TATA binding protein (or TFIID)-TFIIB-RNA polymerase II-TFIIF preinitiation complex.
Molecular and cellular biology 2000;20(1):113-25.
1999: Shwu-Yuan Wu; Mary C Thomas; Samuel Y Hou; V Likhite; Cheng-Ming Chiang
Isolation of mouse TFIID and functional characterization of TBP and TFIID in mediating estrogen receptor and chromatin transcription.
The Journal of biological chemistry 1999;274(33):23480-90.
1998: E Kershnar; Shwu-Yuan Wu; Cheng-Ming Chiang
Immunoaffinity purification and functional characterization of human transcription factor IIH and RNA polymerase II from clonal cell lines that conditionally express epitope-tagged subunits of the multiprotein complexes.
The Journal of biological chemistry 1998;273(51):34444-53.
1998: Shwu-Yuan Wu; E Kershnar; Cheng-Ming Chiang
TAFII-independent activation mediated by human TBP in the presence of the positive cofactor PC4.
The EMBO journal 1998;17(15):4478-90.
1998: Shwu-Yuan Wu; Cheng-Ming Chiang
Properties of PC4 and an RNA polymerase II complex in directing activated and basal transcription in vitro.
The Journal of biological chemistry 1998;273(20):12492-8.
1996: Shwu-Yuan Wu; Cheng-Ming Chiang
Establishment of stable cell lines expressing potentially toxic proteins by tetracycline-regulated and epitope-tagging methods.
BioTechniques 1996;21(4):718-22, 724-5.