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Marcel Wubbolts

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Johannes Bongaerts; Roel Bovenberg; Robert Bujnicki; Simon Esser; Dirk Franke; Christoph Grondal; Stefan Kozak; Anja Kurutsch; Volker Lorbach; Michael A Müller; Martin Nieger; Leon Raeven; Melanie Schürmann; Georg A Sprenger; Ralf Takors; Natalie Trachtmann; Marcel Wubbolts; Lóay Al-Momani; Michael Müller
Diversity-oriented production of metabolites derived from chorismate and their use in organic synthesis.
Manuela Hermann; Martin U Kietzmann; Mirela Ivancić; Christoph Zenzmaier; Ruud Luiten; Wolfgang Skranc; Marcel Wubbolts; Margit Winkler; Ruth Birner-Gruenberger; Harald Pichler; Helmut Schwab
Alternative pig liver esterase (APLE) - cloning, identification and functional expression in Pichia pastoris of a versatile new biocatalyst.
Richard Gaisberger; Roland Weis; Ruud Luiten; Wolfgang Skranc; Marcel Wubbolts; Herfried Griengl; Anton Glieder
Counteracting expression deficiencies by anticipating posttranslational modification of PaHNL5-L1Q-A111G by genetic engineering.

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All Publications

2011: Johannes Bongaerts; Roel Bovenberg; Robert Bujnicki; Simon Esser; Dirk Franke; Christoph Grondal; Stefan Kozak; Anja Kurutsch; Volker Lorbach; Michael A Müller; Martin Nieger; Leon Raeven; Melanie Schürmann; Georg A Sprenger; Ralf Takors; Natalie Trachtmann; Marcel Wubbolts; Lóay Al-Momani; Michael Müller
Diversity-oriented production of metabolites derived from chorismate and their use in organic synthesis.
Angewandte Chemie (International ed. in English) 2011;50(34):7781-6.
2008: Manuela Hermann; Martin U Kietzmann; Mirela Ivancić; Christoph Zenzmaier; Ruud Luiten; Wolfgang Skranc; Marcel Wubbolts; Margit Winkler; Ruth Birner-Gruenberger; Harald Pichler; Helmut Schwab
Alternative pig liver esterase (APLE) - cloning, identification and functional expression in Pichia pastoris of a versatile new biocatalyst.
Journal of biotechnology 2008;133(3):301-10.
2007: Richard Gaisberger; Roland Weis; Ruud Luiten; Wolfgang Skranc; Marcel Wubbolts; Herfried Griengl; Anton Glieder
Counteracting expression deficiencies by anticipating posttranslational modification of PaHNL5-L1Q-A111G by genetic engineering.
Journal of biotechnology 2007;129(1):30-8.
2006: Stefan Jennewein; Martin Schürmann; Michael Wolberg; Iris Hilker; Ruud Luiten; Marcel Wubbolts; Daniel Mink
Directed evolution of an industrial biocatalyst: 2-deoxy-D-ribose 5-phosphate aldolase.
Biotechnology journal 2006;1(5):537-48.
2006: Ulrike Müller; Friso van Assema; Michele Gunsior; Sonja Orf; Susanne Kremer; Dick Schipper; Anja Wagemans; Craig A Townsend; Theo Sonke; Roel Bovenberg; Marcel Wubbolts
Metabolic engineering of the E. coli L-phenylalanine pathway for the production of D-phenylglycine (D-Phg).
Metabolic engineering 2006;8(3):196-208.
2006: Bert van Loo; Jaap Kingma; Michael Arand; Marcel Wubbolts; Dick B Janssen
Diversity and biocatalytic potential of epoxide hydrolases identified by genome analysis.
Applied and environmental microbiology 2006;72(4):2905-17.
2005: Theo Sonke; Sandra Ernste; Renate F Tandler; Bernard Kaptein; Wilco P H Peeters; Friso B J van Assema; Marcel Wubbolts; Hans E Schoemaker
L-selective amidase with extremely broad substrate specificity from Ochrobactrum anthropi NCIMB 40321.
Applied and environmental microbiology 2005;71(12):7961-73.
2005: Sven Panke; Marcel Wubbolts
Advances in biocatalytic synthesis of pharmaceutical intermediates.
Current opinion in chemical biology 2005;9(2):188-94.
2005: Tino Polen; Marco Krämer; Johannes Bongaerts; Marcel Wubbolts; Volker F Wendisch
The global gene expression response of Escherichia coli to L-phenylalanine.
Journal of biotechnology 2005;115(3):221-37.
2004: Roland Weis; Ruud Luiten; Wolfgang Skranc; Helmut Schwab; Marcel Wubbolts; Anton Glieder
Reliable high-throughput screening with Pichia pastoris by limiting yeast cell death phenomena.
FEMS yeast research 2004;5(2):179-89.
2004: Sven Panke; Martin Held; Marcel Wubbolts
Trends and innovations in industrial biocatalysis for the production of fine chemicals.
Current opinion in biotechnology 2004;15(4):272-9.
2004: Bert van Loo; Jeffrey H Lutje Spelberg; Jaap Kingma; Theo Sonke; Marcel Wubbolts; Dick B Janssen
Directed evolution of epoxide hydrolase from A. radiobacter toward higher enantioselectivity by error-prone PCR and DNA shuffling.
Chemistry & biology 2004;11(7):981-90.
2003: Anton Glieder; Roland Weis; Wolfgang Skranc; Peter Poechlauer; Ingrid Dreveny; Sandra Majer; Marcel Wubbolts; Helmut Schwab; Karl Gruber
Comprehensive step-by-step engineering of an (R)-hydroxynitrile lyase for large-scale asymmetric synthesis.
Angewandte Chemie (International ed. in English) 2003;42(39):4815-8.
2003: Marco Krämer; Johannes Bongaerts; Roel Bovenberg; Susanne Kremer; Ulrike Müller; Sonja Orf; Marcel Wubbolts; Leon Raeven
Metabolic engineering for microbial production of shikimic acid.
Metabolic engineering 2003;5(4):277-83.
2003: Hans E Schoemaker; Daniel Mink; Marcel Wubbolts
Dispelling the myths--biocatalysis in industrial synthesis.
Science (New York, N.Y.) 2003;299(5613):1694-7.
2002: Sven Panke; Martin Held; Marcel Wubbolts; Bernard Witholt; Andreas Schmid
Pilot-scale production of (S)-styrene oxide from styrene by recombinant Escherichia coli synthesizing styrene monooxygenase.
Biotechnology and bioengineering 2002;80(1):33-41.
2002: D Maass; MR Gerigk; A Kreutzer; Dirk Weuster-Botz; Marcel Wubbolts; Ralf Takors
Integrated L-phenylalanine separation in an E. coli fed-batch process: from laboratory to pilot scale.
Bioprocess and biosystems engineering 2002;25(2):85-96.
2002: MR Gerigk; D Maass; A Kreutzer; Georg A Sprenger; Johannes Bongaerts; Marcel Wubbolts; Ralf Takors
Enhanced pilot-scale fed-batch L-phenylalanine production with recombinant Escherichia coli by fully integrated reactive extraction.
Bioprocess and biosystems engineering 2002;25(1):43-52.
2002: Sven Panke; Marcel Wubbolts
Enzyme technology and bioprocess engineering.
Current opinion in biotechnology 2002;13(2):111-6.
2001: Johannes Bongaerts; Marco Krämer; Ulrike Müller; L Raeven; Marcel Wubbolts
Metabolic engineering for microbial production of aromatic amino acids and derived compounds.
Metabolic engineering 2001;3(4):289-300.
2001: A Schmid; J S Dordick; B Hauer; A Kiener; Marcel Wubbolts; Bernard Witholt
Industrial biocatalysis today and tomorrow.
Nature 2001;409(6817):258-68.
2001: Ulrike Müller; Johannes Bongaerts; Roel Bovenberg; R Jossek; Marco Krämer; J Linnemann; S Müschen; S Ritterbecks; Georg A Sprenger; Marcel Wubbolts
Metabolic engineering to produce fine chemicals in Escherichia coli.
Mededelingen (Rijksuniversiteit te Gent. Fakulteit van de Landbouwkundige en Toegepaste Biologische Wetenschappen) 2001;66(3a):215-7.
2000: Sven Panke; Marcel Wubbolts; Andreas Schmid; Bernard Witholt
Production of enantiopure styrene oxide by recombinant Escherichia coli synthesizing a two-component styrene monooxygenase.
Biotechnology and bioengineering 2000;69(1):91-100.
1999: Sven Panke; V de Lorenzo; A Kaiser; Bernard Witholt; Marcel Wubbolts
Engineering of a stable whole-cell biocatalyst capable of (S)-styrene oxide formation for continuous two-liquid-phase applications.
Applied and environmental microbiology 1999;65(12):5619-23.
1999: S Schneider; Marcel Wubbolts; G Oesterhelt; Dominique Sanglard; Bernard Witholt
Controlled regioselectivity of fatty acid oxidation by whole cells producing cytochrome P450BM-3 monooxygenase under varied dissolved oxygen concentrations.
Biotechnology and bioengineering 1999;64(3):333-41.
1999: Martin Held; Andreas Schmid; Hans-Peter E Kohler; WA Suske; Bernard Witholt; Marcel Wubbolts
An integrated process for the production of toxic catechols from toxic phenols based on a designer biocatalyst.
Biotechnology and bioengineering 1999;62(6):641-8.
1998: S Schneider; Marcel Wubbolts; Dominique Sanglard; Bernard Witholt
Biocatalyst engineering by assembly of fatty acid transport and oxidation activities for In vivo application of cytochrome P-450BM-3 monooxygenase.
Applied and environmental microbiology 1998;64(10):3784-90.
1998: Sven Panke; Bernard Witholt; Andreas Schmid; Marcel Wubbolts
Towards a biocatalyst for (S)-styrene oxide production: characterization of the styrene degradation pathway of Pseudomonas sp. strain VLB120.
Applied and environmental microbiology 1998;64(6):2032-43.
1997: WA Suske; Martin Held; Andreas Schmid; Thomas Fleischmann; Marcel Wubbolts; Hans-Peter E Kohler
Purification and characterization of 2-hydroxybiphenyl 3-monooxygenase, a novel NADH-dependent, FAD-containing aromatic hydroxylase from Pseudomonas azelaica HBP1.
The Journal of biological chemistry 1997;272(39):24257-65.
1994: J B van Beilen; Marcel Wubbolts; Bernard Witholt
Genetics of alkane oxidation by Pseudomonas oleovorans.
Biodegradation 1994;5(3-4):161-74.
1994: Marcel Wubbolts; P Reuvekamp; Bernard Witholt
TOL plasmid-specified xylene oxygenase is a wide substrate range monooxygenase capable of olefin epoxidation.
Enzyme and microbial technology 1994;16(7):608-15.
1992: A Delgado; Marcel Wubbolts; M A Abril; J L Ramos
Nitroaromatics Are Substrates for the TOL Plasmid Upper-Pathway Enzymes.
Applied and environmental microbiology 1992;58(1):415-7.
1990: Marcel Wubbolts; Peter Terpstra; J B van Beilen; J Kingma; H A Meesters; Bernard Witholt
Variation of cofactor levels in Escherichia coli. Sequence analysis and expression of the pncB gene encoding nicotinic acid phosphoribosyltransferase.
The Journal of biological chemistry 1990;265(29):17665-72.