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Julia Wulfkuhle

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Angela Zupa; Elisa Pin; Alessandra Silvestri; Julia D Wulfkuhle; Michele Aieta; Claudio Belluco; Jianghong Deng; Giuseppina Improta; Lance Liotta; Enzo Mammano; Pellegrino Musto; Donato Nitti; Emanuel Petricoin
A pilot characterization of human lung NSCLC by protein pathway activation mapping.
Julia D Wulfkuhle; Mariaelena Pierobon; Kai Tran; Axel Walch; Christine Waldhör; Claudia Wolff; Ingrid Becker; Karl-Friedrich Becker; Daniela Berg; Holger Bronger; Angela DeMichele; Jianghong Deng; Virginia Espina; Laura Esserman; Heinz Höfler; Julie Illi; Rupert Langer; Lance A Liotta; Emanuel F Petricoin
Molecular analysis of HER2 signaling in human breast cancer by functional protein pathway activation mapping.
Ton van Agthoven; Julia D Wulfkuhle; Marcia F E Godinho; Emanuel F Petricoin; Lambert C J Dorssers
Protein pathway activation mapping reveals molecular networks associated with antiestrogen resistance in breast cancer cell lines.

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All Publications

2012: Angela Zupa; Elisa Pin; Alessandra Silvestri; Julia D Wulfkuhle; Michele Aieta; Claudio Belluco; Jianghong Deng; Giuseppina Improta; Lance Liotta; Enzo Mammano; Pellegrino Musto; Donato Nitti; Emanuel Petricoin
A pilot characterization of human lung NSCLC by protein pathway activation mapping.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2012;7(12):1755-66.
2012: Julia D Wulfkuhle; Mariaelena Pierobon; Kai Tran; Axel Walch; Christine Waldhör; Claudia Wolff; Ingrid Becker; Karl-Friedrich Becker; Daniela Berg; Holger Bronger; Angela DeMichele; Jianghong Deng; Virginia Espina; Laura Esserman; Heinz Höfler; Julie Illi; Rupert Langer; Lance A Liotta; Emanuel F Petricoin
Molecular analysis of HER2 signaling in human breast cancer by functional protein pathway activation mapping.
Clinical cancer research : an official journal of the American Association for Cancer Research 2012;18(23):6426-35.
2012: Ton van Agthoven; Julia D Wulfkuhle; Marcia F E Godinho; Emanuel F Petricoin; Lambert C J Dorssers
Protein pathway activation mapping reveals molecular networks associated with antiestrogen resistance in breast cancer cell lines.
International journal of cancer. Journal international du cancer 2012;131(9):1998-2007.
2012: M F E Godinho; Maxime P Look; E F Petricoin; Anieta M Sieuwerts; Stefan Sleijfer; Lambert C J Dorssers; John A Foekens; Julia D Wulfkuhle; Ton van Agthoven
BCAR4 induces antioestrogen resistance but sensitises breast cancer to lapatinib.
British journal of cancer 2012;107(6):947-55.
2012: Michelle M Raiszadeh; Mark M Ross; Paul S Russo; Mary Ann Schaepper; Thomas Soeprono; Monica Strom; Julia D Wulfkuhle; Weidong Zhou; Jianghong Deng; April Dickson; Cindy Dickson; Lance A Liotta; Daniel Ng; Carolina Osorio; Emanuel F Petricoin; Wolff M Kirsch
Proteomic analysis of eccrine sweat: implications for the discovery of schizophrenia biomarker proteins.
Journal of proteome research 2012;11(4):2127-39.
2012: Catherine Ibarra-Drendall; Nicole M Kuderer; Laurie W Lee; Siya Lem; Lance A Liotta; Priya Mehta; Emanuel F Petricoin; Patrick G Pilie; Melanie Shivraj; Nora Tolbert; Michelle M Troch; Lee G Wilke; Jamila Williams; Julia D Wulfkuhle; Dihua Yu; Carola M Zalles; Joseph C Baker; William T Barry; Gloria Broadwater; Anne C Ford; Abigail W Hoffman; Victoria L Seewaldt
Pilot and feasibility study: prospective proteomic profiling of mammary epithelial cells from high-risk women provides evidence of activation of pro-survival pathways.
Breast cancer research and treatment 2012;132(2):487-98.
2011: Daniel Gioeli; Emanuel F Petricoin; Judith Sebolt-Leopold; Stefan Bekiranov; Mark Conaway; Julia D Wulfkuhle; Winfried Wunderlich; Michael J Weber
Compensatory pathways induced by MEK inhibition are effective drug targets for combination therapy against castration-resistant prostate cancer.
Molecular cancer therapeutics 2011;10(9):1581-90.
2011: Wenle Xia; Xiao-Yi Yang; Sumin Zhao; Rongrong Zong; Julia D Wulfkuhle; Sarah S Bacus; Kimberly L Blackwell; Timothy M Clay; Zachary Conrad Hartman; Jia He; Leihua Liu; Zuguo Liu; H Kim Lyerly; Yubin Mao; Takuya Osada; Emanuel F Petricoin; Neil L Spector
Truncated ErbB2 expressed in tumor cell nuclei contributes to acquired therapeutic resistance to ErbB2 kinase inhibitors.
Molecular cancer therapeutics 2011;10(8):1367-74.
2011: Giuseppina Improta; Lance A Liotta; Pellegrino Musto; Emanuel F Petricoin; Michele Aieta; William Broaddus; Jianghong Deng; Helen Fillmore; Angela Zupa; Julia D Wulfkuhle
Protein pathway activation mapping of brain metastasis from lung and breast cancers reveals organ type specific drug target activation.
Journal of proteome research 2011;10(7):3089-97.
2011: Troy Anderson; Emanuel Petricoin; Julia D Wulfkuhle; Raimond L Winslow
High resolution mapping of the cardiac transmural proteome using reverse phase protein microarrays.
Molecular & cellular proteomics : MCP 2011;10(7):M111.008037.
2011: Patrick G Pilie; Catherine Ibarra-Drendall; Michelle M Troch; Gloria Broadwater; William T Barry; Emanuel F Petricoin; Julia D Wulfkuhle; Lance A Liotta; Siya Lem; Joseph C Baker; April Stouder; Anne C Ford; Lee G Wilke; Carola M Zalles; Priya Mehta; Jamila Williams; Melanie Shivraj; Zuowei Su; Joseph Geradts; Dihua Yu; Victoria L Seewaldt
Protein microarray analysis of mammary epithelial cells from obese and nonobese women at high risk for breast cancer: feasibility data.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2011;20(3):476-82.
2009: Troy Anderson; Julia D Wulfkuhle; Lance Liotta; Raimond L Winslow; Emanuel Petricoin
Improved reproducibility of reverse-phase protein microarrays using array microenvironment normalization.
Proteomics 2009;9(24):5562-6.
2009: Dmytro M Havaleshko; Steven Christopher Smith; HyungJun Cho; Sooyoung Cheon; Charles R Owens; Jae K Lee; Lance A Liotta; Virginia Espina; Julia D Wulfkuhle; Emanuel F Petricoin; Dan Theodorescu
Comparison of global versus epidermal growth factor receptor pathway profiling for prediction of lapatinib sensitivity in bladder cancer.
Neoplasia (New York, N.Y.) 2009;11(11):1185-93.
2009: Christian Gulmann; Katherine M Sheehan; Ronán M Conroy; Julia D Wulfkuhle; Virginia Espina; Michelle J Mullarkey; Elaine W Kay; Lance A Liotta; Emanuel F Petricoin
Quantitative cell signalling analysis reveals down-regulation of MAPK pathway activation in colorectal cancer.
The Journal of pathology 2009;218(4):514-9.
2009: Robert L Grubb; Jianghong Deng; Peter A Pinto; James L Mohler; Arul M Chinnaiyan; Mark Rubin; W Marston Linehan; Lance A Liotta; Emanuel F Petricoin; Julia D Wulfkuhle
Pathway biomarker profiling of localized and metastatic human prostate cancer reveal metastatic and prognostic signatures.
Journal of proteome research 2009;8(6):3044-54.
2008: Julia D Wulfkuhle; Runa Speer; Mariaelena Pierobon; Julie Laird; Virginia Espina; Jianghong Deng; Enzo Mammano; Sherry X Yang; Sandra M Swain; Donato Nitti; Laura J Esserman; Claudio Belluco; Lance A Liotta; Emanuel F Petricoin
Multiplexed cell signaling analysis of human breast cancer applications for personalized therapy.
Journal of proteome research 2008;7(4):1508-17.
2008: Virginia Espina; Julia D Wulfkuhle; Valerie S Calvert; Lance A Liotta; Emanuel F Petricoin
Reverse phase protein microarrays for theranostics and patient-tailored therapy.
Methods in molecular biology (Clifton, N.J.) 2008;441():113-28.
2007: Jiangbing Zhou; Julia D Wulfkuhle; Hao Zhang; Peihua Gu; Yanqin Yang; Jianghong Deng; Joseph B Margolick; Lance A Liotta; Emanuel F Petricoin; Ying Zhang
Activation of the PTEN/mTOR/STAT3 pathway in breast cancer stem-like cells is required for viability and maintenance.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(41):16158-63.
2007: Amy V Rapkiewicz; Virginia Espina; Jo Anne Zujewski; Peter F Lebowitz; Armando C Filie; Julia D Wulfkuhle; Kevin A Camphausen; Emanuel F Petricoin; Lance A Liotta; Andrea Abati
The needle in the haystack: application of breast fine-needle aspirate samples to quantitative protein microarray technology.
Cancer 2007;111(3):173-84.
2007: Runa Speer; Julia D Wulfkuhle; Virginia Espina; Robyn Aurajo; Kirsten H Edmiston; Lance A Liotta; Emanuel F Petricoin
Development of reverse phase protein microarrays for clinical applications and patient-tailored therapy.
Cancer genomics & proteomics 2007;4(3):157-64.
2007: Virginia Espina; Julia D Wulfkuhle; Valerie S Calvert; Emanuel F Petricoin; Lance A Liotta
Reverse phase protein microarrays for monitoring biological responses.
Methods in molecular biology (Clifton, N.J.) 2007;383():321-36.
2006: Julia D Wulfkuhle; Kirsten H Edmiston; Lance A Liotta; Emanuel F Petricoin
Technology insight: pharmacoproteomics for cancer--promises of patient-tailored medicine using protein microarrays.
Nature clinical practice. Oncology 2006;3(5):256-68.
2006: Virginia Espina; Julia D Wulfkuhle; Valerie S Calvert; Amy VanMeter; Weidong Zhou; George Coukos; David H Geho; Emanuel F Petricoin; Lance A Liotta
Laser-capture microdissection.
Nature protocols 2006;1(2):586-603.
2005: Runa Speer; Julia D Wulfkuhle; Lance A Liotta; Emanuel F Petricoin
Reverse-phase protein microarrays for tissue-based analysis.
Current opinion in molecular therapeutics 2005;7(3):240-5.
2005: David H Geho; Nicholas Lahar; Prem Gurnani; Michael Huebschman; Paul C Herrmann; Virginia Espina; Alice Shi; Julia D Wulfkuhle; Harold R Garner; Emanuel F Petricoin; Lance A Liotta; Kevin P Rosenblatt
Pegylated, steptavidin-conjugated quantum dots are effective detection elements for reverse-phase protein microarrays.
Bioconjugate chemistry 2005;16(3):559-66.
2005: Katherine M Sheehan; Valerie S Calvert; Elaine W Kay; Yiling Lu; David Fishman; Virginia Espina; Joy Aquino; Runa Speer; Robyn Araujo; Gordon B Mills; Lance A Liotta; Emanuel F Petricoin; Julia D Wulfkuhle
Use of reverse phase protein microarrays and reference standard development for molecular network analysis of metastatic ovarian carcinoma.
Molecular & cellular proteomics : MCP 2005;4(4):346-55.
2004: Julia D Wulfkuhle; Virginia Espina; Lance A Liotta; Emanuel F Petricoin
Genomic and proteomic technologies for individualisation and improvement of cancer treatment.
European journal of cancer (Oxford, England : 1990) 2004;40(17):2623-32.
2004: Virginia Espina; Elisa C Woodhouse; Julia D Wulfkuhle; Heather D Asmussen; Emanuel F Petricoin; Lance A Liotta
Protein microarray detection strategies: focus on direct detection technologies.
Journal of immunological methods 2004;290(1-2):121-33.
2004: Rani K Hasan; Julia D Wulfkuhle; Lance A Liotta; Emanuel F Petricoin
STUDENTJAMA. Molecular technologies for personalized cancer management.
JAMA : the journal of the American Medical Association 2004;291(13):1644-5.
2004: Emanuel F Petricoin; Julia D Wulfkuhle; Virginia Espina; Lance A Liotta
Clinical proteomics: revolutionizing disease detection and patient tailoring therapy.
Journal of proteome research 2004;3(2):209-17.
2003: Virginia Espina; Arpita I Mehta; Mary E Winters; Valerie S Calvert; Julia D Wulfkuhle; Emanuel F Petricoin; Lance A Liotta
Protein microarrays: molecular profiling technologies for clinical specimens.
Proteomics 2003;3(11):2091-100.
2003: Julia D Wulfkuhle; Joy A Aquino; Valerie S Calvert; David A Fishman; George Coukos; Lance A Liotta; Emanuel F Petricoin
Signal pathway profiling of ovarian cancer from human tissue specimens using reverse-phase protein microarrays.
Proteomics 2003;3(11):2085-90.
2003: Lance A Liotta; Virginia Espina; Arpita I Mehta; Valerie S Calvert; Kevin P Rosenblatt; David H Geho; Peter J Munson; Lynn Young; Julia D Wulfkuhle; Emanuel F Petricoin
Protein microarrays: meeting analytical challenges for clinical applications.
Cancer cell 2003;3(4):317-25.
2003: Julia D Wulfkuhle; Lance A Liotta; Emanuel F Petricoin
Proteomic applications for the early detection of cancer.
Nature reviews. Cancer 2003;3(4):267-75.
2003: Julia D Wulfkuhle; Cloud P Paweletz; Patricia S Steeg; Emanuel F Petricoin; Lance A Liotta
Proteomic approaches to the diagnosis, treatment, and monitoring of cancer.
Advances in experimental medicine and biology 2003;532():59-68.
2002: Julia D Wulfkuhle; Dennis C Sgroi; Henry C Krutzsch; Kelley McLean; Kelly McGarvey; Melodie Knowlton; She Chen; Hongjun Shu; Aysegul Sahin; Raffael Kurek; Diethelm Wallwiener; Maria J Merino; Emanuel F Petricoin; Yingming Zhao; Patricia S Steeg
Proteomics of human breast ductal carcinoma in situ.
Cancer research 2002;62(22):6740-9.
2001: Julia D Wulfkuhle; K C McLean; Cloud P Paweletz; Dennis C Sgroi; Bruce J Trock; Patricia S Steeg; Emanuel F Petricoin
New approaches to proteomic analysis of breast cancer.
Proteomics 2001;1(10):1205-15.
2000: Qun Zhou; Julia D Wulfkuhle; Taoufik Ouatas; PI Fukushima; Maryalice Stetler-Stevenson; Fred R Miller; Patricia S Steeg
Cyclin D1 overexpression in a model of human breast premalignancy: preferential stimulation of anchorage-independent but not anchorage-dependent growth is associated with increased cdk2 activity.
Breast cancer research and treatment 2000;59(1):27-39.