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Stephan Wullschleger

Research Profile

Chemicals & Drugs

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Physiology

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Publications

TOP 3
Anguraj Sadanandam; Bertram Wiedenmann; Stephan Wullschleger; Lewis C Cantley; Eric A Collisson; Maguy Del Rio; William J Gibb; Joe W Gray; Carsten Grotzinger; Krisztian Homicsko; William A Lannon; Benoit Lhermitte; Costas A Lyssiotis; Adam B Olshen; Liliane C Gonzalez Ostos; Douglas Hanahan
A colorectal cancer classification system that associates cellular phenotype and responses to therapy.
Ivan Landego; Dario R Alessi; Ian W Gibson; Nipun Jayachandran; Angela Miller; Stephan Wullschleger; Ting-ting Zhang; Aaron J Marshall
Interaction of TAPP adapter proteins with phosphatidylinositol (3,4)-bisphosphate regulates B-cell activation and autoantibody production.
Stephan Wullschleger; Juan M García-Martínez; Suzanne L Duce
Quantitative MRI establishes the efficacy of PI3K inhibitor (GDC-0941) multi-treatments in PTEN-deficient mice lymphoma.

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All Publications

2013: Anguraj Sadanandam; Bertram Wiedenmann; Stephan Wullschleger; Lewis C Cantley; Eric A Collisson; Maguy Del Rio; William J Gibb; Joe W Gray; Carsten Grotzinger; Krisztian Homicsko; William A Lannon; Benoit Lhermitte; Costas A Lyssiotis; Adam B Olshen; Liliane C Gonzalez Ostos; Douglas Hanahan
A colorectal cancer classification system that associates cellular phenotype and responses to therapy.
Nature medicine 2013;19(5):619-25.
2012: Ivan Landego; Dario R Alessi; Ian W Gibson; Nipun Jayachandran; Angela Miller; Stephan Wullschleger; Ting-ting Zhang; Aaron J Marshall
Interaction of TAPP adapter proteins with phosphatidylinositol (3,4)-bisphosphate regulates B-cell activation and autoantibody production.
European journal of immunology 2012;42(10):2760-70.
2012: Stephan Wullschleger; Juan M García-Martínez; Suzanne L Duce
Quantitative MRI establishes the efficacy of PI3K inhibitor (GDC-0941) multi-treatments in PTEN-deficient mice lymphoma.
Anticancer research 2012;32(2):415-20.
2011: Laura R Pearce; Eeva M Sommer; Kei Sakamoto; Stephan Wullschleger; Dario R Alessi
Protor-1 is required for efficient mTORC2-mediated activation of SGK1 in the kidney.
The Biochemical journal 2011;436(1):169-79.
2011: J M García-Martínez; Stephan Wullschleger; G Preston; S Guichard; S Fleming; Dario R Alessi; S L Duce
Effect of PI3K- and mTOR-specific inhibitors on spontaneous B-cell follicular lymphomas in PTEN/LKB1-deficient mice.
British journal of cancer 2011;104(7):1116-25.
2011: Stephan Wullschleger; David H Wasserman; Alex Gray; Kei Sakamoto; Dario R Alessi
Role of TAPP1 and TAPP2 adaptor binding to PtdIns(3,4)P2 in regulating insulin sensitivity defined by knock-in analysis.
The Biochemical journal 2011;434(2):265-74.
2011: Stephan Wullschleger; Kei Sakamoto; Lana Johnstone; Suzanne Duce; Stewart Fleming; Dario R Alessi
How moderate changes in Akt T-loop phosphorylation impact on tumorigenesis and insulin resistance.
Disease models & mechanisms 2011;4(1):95-103.
2008: Xu Huang; Stephan Wullschleger; Natalia Shpiro; Victoria A McGuire; Kei Sakamoto; Yvonne L Woods; Wendy McBurnie; Stewart Fleming; Dario R Alessi
Important role of the LKB1-AMPK pathway in suppressing tumorigenesis in PTEN-deficient mice.
The Biochemical journal 2008;412(2):211-21.
2008: Jose R Bayascas; Stephan Wullschleger; Kei Sakamoto; Juan M García-Martínez; Carol Clacher; David Komander; Daan M F van Aalten; Krishna M Boini; Florian Lang; Christopher Lipina; Lisa Logie; Calum Sutherland; John A Chudek; Janna A van Diepen; Peter J Voshol; John M Lucocq; Dario R Alessi
Mutation of the PDK1 PH domain inhibits protein kinase B/Akt, leading to small size and insulin resistance.
Molecular and cellular biology 2008;28(10):3258-72.
2007: Laura R Pearce; Xu Huang; Jérôme Boudeau; Rafał Pawłowski; Stephan Wullschleger; Maria Deak; Adel F M Ibrahim; Robert Gourlay; Mark Magnuson; Dario R Alessi
Identification of Protor as a novel Rictor-binding component of mTOR complex-2.
The Biochemical journal 2007;405(3):513-22.
2006: Olga Göransson; Maria Deak; Stephan Wullschleger; Nick A Morrice; Alan R Prescott; Dario R Alessi
Regulation of the polarity kinases PAR-1/MARK by 14-3-3 interaction and phosphorylation.
Journal of cell science 2006;119(Pt 19):4059-70.
2006: Stephan Wullschleger; Robbie Loewith; Michael N Hall
TOR signaling in growth and metabolism.
Cell 2006;124(3):471-84.
2005: Stephan Wullschleger; Robbie Loewith; Wolfgang Oppliger; Michael N Hall
Molecular organization of target of rapamycin complex 2.
The Journal of biological chemistry 2005;280(35):30697-704.
2005: Yoshiaki Kamada; Yuko Fujioka; Nobuo N Suzuki; Fuyuhiko Inagaki; Stephan Wullschleger; Robbie Loewith; Michael N Hall; Yoshinori Ohsumi
Tor2 directly phosphorylates the AGC kinase Ypk2 to regulate actin polarization.
Molecular and cellular biology 2005;25(16):7239-48.
2002: Robbie Loewith; Estela Jacinto; Stephan Wullschleger; Anja Lorberg; José L Crespo; Débora Bonenfant; Wolfgang Oppliger; Paul Jenoe; Michael N Hall
Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control.
Molecular cell 2002;10(3):457-68.