Toshihiro Akaike

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Chemicals & Drugs

Living Beings

Anatomy

Physiology

Sign-in to see full Profile

Sign-in to see all Coauthors

Publications

TOP 3
Jere D; Jiang H L; Arote R; Kim Y K; Choi Y J; Cho M H; Akaike T; Cho C S
Degradable polyethylenimines as DNA and small interfering RNA carriers.
Zohra Fatema T; Chowdhury Ezharul H; Akaike Toshihiro
High performance mRNA transfection through carbonate apatite-cationic liposome conjugates.
Yamaki Kazumasa; Harada Ichiro; Goto Mitsuaki; Cho Chong-Su; Akaike Toshihiro
Regulation of cellular morphology using temperature-responsive hydrogel for integrin-mediated mechanical force stimulation.

Sign-in to see all Publications

Sign in free and see...

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the visualized research activity
of experts around the globe

Sign-in to see more

Geonetwork of Toshihiro Akaike (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

Sign-in to see more

All Publications

2009: Jere D; Jiang H L; Arote R; Kim Y K; Choi Y J; Cho M H; Akaike T; Cho C S
Degradable polyethylenimines as DNA and small interfering RNA carriers.
Expert opinion on drug delivery 2009;6(8):827-34.
2009: Zohra Fatema T; Chowdhury Ezharul H; Akaike Toshihiro
High performance mRNA transfection through carbonate apatite-cationic liposome conjugates.
Biomaterials 2009;30(23-24):4006-13.
2009: Yamaki Kazumasa; Harada Ichiro; Goto Mitsuaki; Cho Chong-Su; Akaike Toshihiro
Regulation of cellular morphology using temperature-responsive hydrogel for integrin-mediated mechanical force stimulation.
Biomaterials 2009;30(7):1421-7.
2008: Jiang Hu-Lin; Kang Mi Lan; Quan Ji-Shan; Kang Sang Gyun; Akaike Toshihiro; Yoo Han Sang; Cho Chong-Su
The potential of mannosylated chitosan microspheres to target macrophage mannose receptors in an adjuvant-delivery system for intranasal immunization.
Biomaterials 2008;29(12):1931-9.
2008: Hoshiba Takashi; Wakejima Mai; Cho Chong-Su; Shiota Goshi; Akaike Toshihiro
Different regulation of hepatocyte behaviors between natural extracellular matrices and synthetic extracellular matrices by hepatocyte growth factor.
Journal of biomedical materials research. Part A 2008;85(1):228-35.
2008: Hiratsuka Takahiro; Goto Mitsuaki; Kondo Yoshiyuki; Cho Chong-Su; Akaike Toshihiro
Copolymers for hepatocyte-specific targeting carrying galactose and hydrophobic alkyl groups.
Macromolecular bioscience 2008;8(3):231-8.
2008: Kutsuzawa K; Akaike T; Chowdhury Ezharul H
The influence of the cell-adhesive proteins E-cadherin and fibronectin embedded in carbonate-apatite DNA carrier on transgene delivery and expression in a mouse embryonic stem cell line.
Biomaterials 2008;29(3):370-6.
2008: Kutsuzawa K; Maruyama K; Akiyama Y; Akaike T; Chowdhury E H
Efficient transfection of mouse embryonic stem cells with cell-adhesive protein-embedded inorganic nanocarrier.
Analytical biochemistry 2008;372(1):122-4.
2008: Nagaoka Masato; Ise Hirohiko; Harada Ichiro; Koshimizu Uichi; Maruyama Atsushi; Akaike Toshihiro
Embryonic undifferentiated cells show scattering activity on a surface coated with immobilized E-cadherin.
Journal of cellular biochemistry 2008;103(1):296-310.
2007: Kutsuzawa K; Maruyama K; Akiyama Y; Akaike T; Chowdhury E H
Protein kinase C activation enhances transfection efficacy of cell-adhesive protein-anchored carbonate apatite nanocrystals.
Analytical biochemistry 2007;371(1):116-7.
2007: Kim T H; Jiang H L; Nah J W; Cho M H; Akaike T; Cho C S
Receptor-mediated gene delivery using chemically modified chitosan.
Biomedical materials (Bristol, England) 2007;2(3):S95-100.
2007: Sugiura Mika; Nagaoka Masato; Yabuuchi Hikaru; Akaike Toshihiro
Overexpression of MCT8 enhances the differentiation of ES cells into neural progenitors.
Biochemical and biophysical research communications 2007;360(4):741-5.
2007: Zohra F T; Chowdhury E H; Tada S; Hoshiba T; Akaike T
Effective delivery with enhanced translational activity synergistically accelerates mRNA-based transfection.
Biochemical and biophysical research communications 2007;358(1):373-8.
2007: Jiang Hu-Lin; Kim You-Kyoung; Arote Rohidas; Nah Jae-Woon; Cho Myung-Haing; Choi Yun-Jaie; Akaike Toshihiro; Cho Chong-Su
Chitosan-graft-polyethylenimine as a gene carrier.
Journal of controlled release : official journal of the Controlled Release Society 2007;117(2):273-80.
2007: Hoshiba Takashi; Nagahara Hikaru; Cho Chong-Su; Tagawa Yoh-ichi; Akaike Toshihiro
Primary hepatocyte survival on non-integrin-recognizable matrices without the activation of Akt signaling.
Biomaterials 2007;28(6):1093-104.
2007: Choi Sung Won; Makita Naoki; Inoue Satoru; Lesoil Charles; Yamayoshi Asako; Kano Arihiro; Akaike Toshihiro; Maruyama Atsushi
Cationic comb-type copolymers for boosting DNA-fueled nanomachines.
Nano letters 2007;7(1):172-8.
2007: Harada Ichiro; Kim Sung-Gon; Cho Chong Su; Kurosawa Hisashi; Akaike Toshihiro
A simple combined floating and anchored collagen gel for enhancing mechanical strength of culture system.
Journal of biomedical materials research. Part A 2007;80(1):123-30.
2007: Yoo Mi Kyong; Kim In Yong; Kim Eun Mi; Jeong Hwan-Jeong; Lee Chang-Moon; Jeong Yong Yeon; Akaike Toshihiro; Cho Chong Su
Superparamagnetic iron oxide nanoparticles coated with galactose-carrying polymer for hepatocyte targeting.
Journal of biomedicine & biotechnology 2007;2007(10):94740.
2007: Makita Naoki; Choi Sung Won; Kano Arihiro; Yamayoshi Asako; Akaike Toshihiro; Maruyama Atsushi
Effect of cationic comb-type copolymer on quadruplex folding of human telomeric DNA.
Nucleosides, nucleotides & nucleic acids 2007;26(8-9):1115-9.
2007: Chowdhury E H; Akaike Toshihiro
High performance DNA nano-carriers of carbonate apatite: multiple factors in regulation of particle synthesis and transfection efficiency.
International journal of nanomedicine 2007;2(1):101-6.
2006: Chowdhury E H; Akaike T
Fibronectin-coated nano-precipitates of calcium-magnesium phosphate for integrin-targeted gene delivery.
Journal of controlled release : official journal of the Controlled Release Society 2006;116(2):e68-9.
2006: Chowdhury E H; Akaike T
Apatite with less crystallinity is a superior agent for macromolecular drug delivery to mammalian cells.
Journal of controlled release : official journal of the Controlled Release Society 2006;116(2):e42-3.
2006: Kutsuzawa K; Chowdhury E H; Nagaoka M; Maruyama K; Akiyama Y; Akaike T
Surface functionalization of inorganic nano-crystals with fibronectin and E-cadherin chimera synergistically accelerates trans-gene delivery into embryonic stem cells.
Biochemical and biophysical research communications 2006;350(3):514-20.
2006: Hoshiba Takashi; Cho Chong Su; Murakawa Akiko; Okahata Yoshio; Akaike Toshihiro
The effect of natural extracellular matrix deposited on synthetic polymers on cultured primary hepatocytes.
Biomaterials 2006;27(26):4519-28.
2006: Chowdhury E H; Maruyama A; Kano A; Nagaoka M; Kotaka M; Hirose S; Kunou M; Akaike T
pH-sensing nano-crystals of carbonate apatite: effects on intracellular delivery and release of DNA for efficient expression into mammalian cells.
Gene 2006;376(1):87-94.
2006: Ogiwara Kazutaka; Nagaoka Masato; Cho Chong-Su; Akaike Toshihiro
Effect of photo-immobilization of epidermal growth factor on the cellular behaviors.
Biochemical and biophysical research communications 2006;345(1):255-9.
2006: Seo Seog-Jin; Kim In-Yong; Choi Yun-Jaie; Akaike Toshihiro; Cho Chong-Su
Enhanced liver functions of hepatocytes cocultured with NIH 3T3 in the alginate/galactosylated chitosan scaffold.
Biomaterials 2006;27(8):1487-95.
2006: Cho C S; Seo S J; Park I K; Kim S H; Kim T H; Hoshiba T; Harada I; Akaike T
Galactose-carrying polymers as extracellular matrices for liver tissue engineering.
Biomaterials 2006;27(4):576-85.
2006: Seo Seog-Jin; Choi Yun-Jaie; Akaike Toshihiro; Higuchi Akon; Cho Chong-Su
Alginate/galactosylated chitosan/heparin scaffold as a new synthetic extracellular matrix for hepatocytes.
Tissue engineering 2006;12(1):33-44.
2006: Nagaoka Masato; Koshimizu Uichi; Yuasa Shinsuke; Hattori Fumiyuki; Chen Hao; Tanaka Tomofumi; Okabe Masaru; Fukuda Keiichi; Akaike Toshihiro
E-cadherin-coated plates maintain pluripotent ES cells without colony formation.
PloS one 2006;1():e15.
2005: Chowdhury Ezharul H; Akaike Toshihiro
Bio-functional inorganic materials: an attractive branch of gene-based nano-medicine delivery for 21st century.
Current gene therapy 2005;5(6):669-76.
2005: Ogiwara Kazutaka; Nagaoka Masato; Cho Chong-Su; Akaike Toshihiro
Construction of a novel extracellular matrix using a new genetically engineered epidermal growth factor fused to IgG-Fc.
Biotechnology letters 2005;27(20):1633-7.
2005: Zohra F T; Chowdhury E H; Nagaoka M; Akaike T
Drastic effect of nanoapatite particles on liposome-mediated mRNA delivery to mammalian cells.
Analytical biochemistry 2005;345(1):164-6.
2005: Chowdhury E H; Akaike Toshihiro
Rapid isolation of high quality, multimeric plasmid DNA using zwitterionic detergent.
Journal of biotechnology 2005;119(4):343-7.
2005: Chowdhury E H; Nagaoka M; Ogiwara K; Zohra F T; Kutsuzawa K; Tada S; Kitamura C; Akaike T
Integrin-supported fast rate intracellular delivery of plasmid DNA by extracellular matrix protein embedded calcium phosphate complexes.
Biochemistry 2005;44(37):12273-8.
2005: Takei R; Suzuki D; Hoshiba T; Nagaoka M; Seo S J; Cho C S; Akaike T
Role of E-cadherin molecules in spheroid formation of hepatocytes adhered on galactose-carrying polymer as an artificial asialoglycoprotein model.
Biotechnology letters 2005;27(16):1149-56.
2005: Kim Tae Hee; Kim Su Il; Akaike Toshihiro; Cho Chong Su
Synergistic effect of poly(ethylenimine) on the transfection efficiency of galactosylated chitosan/DNA complexes.
Journal of controlled release : official journal of the Controlled Release Society 2005;105(3):354-66.
2005: Yoo Mi Kyong; Choi Hoo Kyun; Kim Tae Hee; Choi Yun Jaie; Akaike Toshihiro; Shirakawa Mayumi; Cho Chong Su
Drug release from xyloglucan beads coated with Eudragit for oral drug delivery.
Archives of pharmacal research 2005;28(6):736-42.
2005: Cook Seung Eun; Park In Kyu; Kim Eun Mi; Jeong Hwan Jeong; Park Tae Gwan; Choi Yun Jaie; Akaike Toshihiro; Cho Chong Su
Galactosylated polyethylenimine-graft-poly(vinyl pyrrolidone) as a hepatocyte-targeting gene carrier.
Journal of controlled release : official journal of the Controlled Release Society 2005;105(1-2):151-63.
2005: Seo Seog-Jin; Akaike Toshihiro; Choi Yun-Jaie; Shirakawa Mayumi; Kang Inn-Kyu; Cho Chong-Su
Alginate microcapsules prepared with xyloglucan as a synthetic extracellular matrix for hepatocyte attachment.
Biomaterials 2005;26(17):3607-15.
2005: Takei R; Seo S J; Cho C S; Okahata Y; Akaike T
Adsorption behaviors of poly(N-p-vinylbenzyl-4-o-beta-d-galactopyranosyl-[1-->4]-d-gluconamide) by quartz-crystal microbalance.
Colloids and surfaces. B, Biointerfaces 2005;42(2):137-40.
2005: Chowdhury E H; Akaike Toshihiro
A bio-recognition device developed onto nano-crystals of carbonate apatite for cell-targeted gene delivery.
Biotechnology and bioengineering 2005;90(4):414-21.
2005: Hirata Kazuya; Ishii Daisuke; Kano Arihiro; Yamayoshi Asako; Akaike Toshihiro; Maruyama Atsushi
Discrimination of single nucleotide polymorphisms by strand exchange assay using partially double-stranded probes.
Nucleic acids symposium series (2004) 2005;(49):223-4.
2005: Makita Naoki; Kano Arihiro; Yamayoshi Asako; Akaike Toshihiro; Maruyama Atsushi
Modulation of highly ordered structures of human telomeric sequence by cationic copolymers.
Nucleic acids symposium series (2004) 2005;(49):53-4.
2004: Park In-Kyu; Jiang Hu-Lin; Cook Seung-Eun; Cho Myung-Haing; Kim Su-Il; Jeong Hwan-Jeong; Akaike Toshihiro; Cho Chong-Su
Galactosylated chitosan (GC)-graft-poly(vinyl pyrrolidone) (PVP) as hepatocyte-targeting DNA carrier: in vitro transfection.
Archives of pharmacal research 2004;27(12):1284-9.
2004: Chowdhury E H; Zohra F T; Tada S; Kitamura C; Akaike T
Fibronectin in collaboration with Mg2+ enhances transgene expression by calcium phosphate coprecipitates.
Analytical biochemistry 2004;335(1):162-4.
2004: Seo S J; Kim S H; Sasagawa T; Choi Y J; Akaike T; Cho C S
Delivery of all trans-retinoic acid (RA) to hepatocyte cell line from RA/galactosyl alpha-cyclodextrin inclusion complex.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2004;58(3):681-7.
2004: Jiang Hu-Lin; Park In-Kyu; Shin Na-Ri; Kang Sang-Gyun; Yoo Han-Sang; Kim Su-Il; Suh Sang-Bong; Akaike Toshihiro; Cho Chong-Su
In vitro study of the immune stimulating activity of an atrophic [correction of athrophic] rhinitis vaccine associated to chitosan microspheres.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2004;58(3):471-6.
2004: Chowdhury E H; Kunou Megumi; Nagaoka Masato; Kundu A K; Hoshiba Takashi; Akaike Toshihiro
High-efficiency gene delivery for expression in mammalian cells by nanoprecipitates of Ca-Mg phosphate.
Gene 2004;341():77-82.
2004: Chowdhury E H; Megumi Kunou; Harada Ichiro; Kundu A K; Akaike Toshihiro
Dramatic effect of Mg2+ on transfecting mammalian cells by DNA/calcium phosphate precipitates.
Analytical biochemistry 2004;328(1):96-7.
2004: Kim Sang-Heon; Hoshiba Takashi; Akaike Toshihiro
Hepatocyte behavior on synthetic glycopolymer matrix: inhibitory effect of receptor-ligand binding on hepatocyte spreading.
Biomaterials 2004;25(10):1813-23.
2004: Takei Yoshiyuki; Maruyama Atsushi; Ferdous Anwarul; Nishimura Yoshiya; Kawano Sunao; Ikejima Kenichi; Okumura Shigetoshi; Asayama Shoichiro; Nogawa Masayuki; Hashimoto Masao; Makino Yoko; Kinoshita Masahiko; Watanabe Sumio; Akaike Toshihiro; Lemasters John J; Sato Nobuhiro
Targeted gene delivery to sinusoidal endothelial cells: DNA nanoassociate bearing hyaluronan-glycocalyx.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004;18(6):699-701.
2004: Jiang Hu-Lin; Park In-Kyu; Shin Na-Ri; Yoo Han-Sang; Akaike Toshihiro; Cho Chong-Su
Controlled release of Bordetella bronchiseptica dermonecrotoxin (BBD) vaccine from BBD-loaded chitosan microspheres in vitro.
Archives of pharmacal research 2004;27(3):346-50.
2004: Choi Sung Won; Sato Yuichi; Akaike Toshihiro; Maruyama Atsushi
Evaluation of comb-type copolymers with different cationic groups as artificial nucleic acid chaperones.
Nucleic acids symposium series (2004) 2004;(48):273-4.
2004: Hirata Kazuya; Sato Yuichi; Kano Arihiro; Akaike Toshihiro; Maruyama Atsushi
Nucleation-synchronized strand displacement for highly sensitive DNA analysis.
Nucleic acids symposium series (2004) 2004;(48):267-8.
2004: Makita Naoki; Inoue Satoru; Akaike Toshihiro; Maruyama Atsushi
Improved performance of a DNA nanomachine by cationic copolymers.
Nucleic acids symposium series (2004) 2004;(48):173-4.
2004: Seo Seog-Jin; Park In-Kyu; Yoo Mi-Kyoung; Shirakawa Mayumi; Akaike Toshihiro; Cho Chong-Su
Xyloglucan as a synthetic extracellular matrix for hepatocyte attachment.
Journal of biomaterials science. Polymer edition 2004;15(11):1375-87.
2004: Choi Sung Won; Sato Yuichi; Akaike Toshihiro; Maruyama Atsushi
Preparation of cationic comb-type copolymer having guanidino moieties and its interaction with DNAs.
Journal of biomaterials science. Polymer edition 2004;15(9):1099-110.
2003: Kim Won Jong; Sato Yuichi; Akaike Toshihiro; Maruyama Atsushi
Cationic comb-type copolymers for DNA analysis.
Nature materials 2003;2(12):815-20.
2003: Kim Sang-Heon; Hoshiba Takashi; Akaike Toshihiro
Effect of carbohydrates attached to polystyrene on hepatocyte morphology on sugar-derivatized polystyrene matrices.
Journal of biomedical materials research. Part A 2003;67(4):1351-9.
2003: Kim Sang-Heon; Kim Jong-Hun; Akaike Toshihiro
Regulation of cell adhesion signaling by synthetic glycopolymer matrix in primary cultured hepatocyte.
FEBS letters 2003;553(3):433-9.
2003: Shimojo Shojiro; Cho Chong-Su; Park In-Kyu; Kunou Megumi; Goto Mitsuaki; Akaike Toshihiro
Helical structure of sugar-carrying polystyrene in aqueous solution by circular dichroism.
Carbohydrate research 2003;338(20):2129-33.
2003: Kundu Anup Kumer; Nagaoka Masato; Chowdhury Ezharul Hoque; Hirose Shinichi; Sasagawa Tadashi; Akaike Toshihiro
IGF-1 induces growth, survival and morphological change of primary hepatocytes on a galactose-bared polymer through both MAPK and beta-catenin pathways.
Cell structure and function 2003;28(4):255-63.
2003: Park In-Kyu; Seo Seog-Jin; Akashi Mitsuru; Akaike Toshihiro; Cho Chong-Su
Controlled release of epidermal growth factor (EGF) from EGF-loaded polymeric nanoparticles composed of polystyrene as core and poly(methacrylic acid) as corona in vitro.
Archives of pharmacal research 2003;26(8):649-52.
2003: Park In-Kyu; Yang Jun; Jeong Hwan-Jeong; Bom Hee-Seung; Harada Ichiro; Akaike Toshihiro; Kim Su-Il; Cho Chong-Su
Galactosylated chitosan as a synthetic extracellular matrix for hepatocytes attachment.
Biomaterials 2003;24(13):2331-7.
2003: Park I K; Kim T H; Kim S I; Park Y H; Kim W J; Akaike T; Cho C S
Visualization of transfection of hepatocytes by galactosylated chitosan-graft-poly(ethylene glycol)/DNA complexes by confocal laser scanning microscopy.
International journal of pharmaceutics 2003;257(1-2):103-10.
2003: Watanabe Yoshifumi; Suzuki Osamu; Haruyama Takahiro; Akaike Toshihiro
Interferon-gamma induces reactive oxygen species and endoplasmic reticulum stress at the hepatic apoptosis.
Journal of cellular biochemistry 2003;89(2):244-53.
2003: Nagaoka Masato; Akaike Toshihiro
Single amino acid substitution in the mouse IgG1 Fc region induces drastic enhancement of the affinity to protein A.
Protein engineering 2003;16(4):243-5.
2003: Watanabe Yoshifumi; Haruyama Takahiro; Akaike Toshihiro
Liver-derived matrix metalloproteinase-9 (gelatinase B) recruits progenitor cells from bone marrow into the blood circulation.
Biological & pharmaceutical bulletin 2003;26(4):564-8.
2003: Chowdhury E H; Sasagawa Tadashi; Nagaoka Masato; Kundu A K; Akaike Toshihiro
Transfecting mammalian cells by DNA/calcium phosphate precipitates: effect of temperature and pH on precipitation.
Analytical biochemistry 2003;314(2):316-8.
2003: Park I K; Ihm J E; Park Y H; Choi Y J; Kim S I; Kim W J; Akaike T; Cho C S
Galactosylated chitosan (GC)-graft-poly(vinyl pyrrolidone) (PVP) as hepatocyte-targeting DNA carrier. Preparation and physicochemical characterization of GC-graft-PVP/DNA complex (1).
Journal of controlled release : official journal of the Controlled Release Society 2003;86(2-3):349-59.
2003: Ishida Koji; Nagahara Hikaru; Kogiso Tomomi; Aso Tomoko; Hayashi Naoaki; Akaike Toshihiro
Cell adhesion aside from integrin system can abrogate anoikis in rat liver cells by down-regulation of FasL expression, not by activation of PI-3K/Akt and ERK signaling pathway.
Biochemical and biophysical research communications 2003;300(1):201-8.
2003: Kim Won Jong; Sato Yuichi; Akaike Toshihiro; Maruyama Atsushi
Polycation-accelerated strand exchange (PASE) for SNPs typing.
Nucleic acids research. Supplement (2001) 2003;(3):273-4.
2003: Maruyama Atsushi; Inoue Satoru; Tajima Kaori; Sato Yuichi; Kim Won Jong; Akaike Toshihiro
Design of artificial nucleic acid chaperones for DNA engineering.
Nucleic acids research. Supplement (2001) 2003;(3):219-20.
2003: Sato Yuichi; Kim Won Jon; Saito Minako; Kano Arihiro; Akaike Toshihiro; Maruyama Atsushi
Cationic comb-type copolymers as an artificial nucleic acid-chaperone: spectroscopic analyses for DNA/copolymer interaction.
Nucleic acids research. Supplement (2001) 2003;(3):129-30.
2002: Kim Won Jong; Akaike Toshihiro; Maruyama Atsushi
DNA strand exchange stimulated by spontaneous complex formation with cationic comb-type copolymer.
Journal of the American Chemical Society 2002;124(43):12676-7.
2002: Chung Taek Woong; Yang Jun; Akaike Toshihiro; Cho Kwang Yong; Nah Jae Woon; Kim Su Il; Cho Chong Su
Preparation of alginate/galactosylated chitosan scaffold for hepatocyte attachment.
Biomaterials 2002;23(14):2827-34.
2002: Kim Sung-Gon; Akaike Toshihiro; Sasagaw Tadashi; Atomi Yoriko; Kurosawa Hisashi
Gene expression of type I and type III collagen by mechanical stretch in anterior cruciate ligament cells.
Cell structure and function 2002;27(3):139-44.
2002: Yang Jun; Goto Mitsuaki; Ise Hirohiko; Cho Chong-Su; Akaike Toshihiro
Galactosylated alginate as a scaffold for hepatocytes entrapment.
Biomaterials 2002;23(2):471-9.
2002: Tajima Kaori; Kim Won-Jong; Akaike Toshihiro; Maruyama Atsushi
Acceleration of DNA strand exchange reaction by cationic polymers.
Nucleic acids research. Supplement (2001) 2002;(2):265-6.
2002: Sato Yuichi; Kim Won Jong; Choi Sung Won; Saito Minako; Kano Arihiro; Akaike Toshihiro; Maruyama Atsushi
Investigation of DNA strand exchange mechanisms mediated by cationic polymers.
Nucleic acids research. Supplement (2001) 2002;(2):59-60.
2002: Shimojo Shojiro; Akaike Toshihiro; Hara Mariko; Higuchi Akon; Park In-Kyu; Cho Chong-Su
Difference in the attachment of hepatocytes between a poly(gamma-benzyl L-glutamate) (PBLG)/poly(N-isopropylacrylamide) (PNIPAAm) diblock copolymer cast surface and a PBlg/PNIPAAm Langmuir-Blodgett one.
Journal of biomaterials science. Polymer edition 2002;13(7):829-41.
2002: Ajioka Itsuki; Akaike Toshihiro; Watanabe Yoshifumi
Ethanolamine is a co-mitogenic factor for proliferation of primary hepatocytes.
Journal of cellular biochemistry 2002;84(2):249-63.
2001: Cho C S; Cho K Y; Park I K; Kim S H; Sasagawa T; Uchiyama M; Akaike T
Receptor-mediated delivery of all trans-retinoic acid to hepatocyte using poly(L-lactic acid) nanoparticles coated with galactose-carrying polystyrene.
Journal of controlled release : official journal of the Controlled Release Society 2001;77(1-2):7-15.
2001: Park I K; Kim T H; Park Y H; Shin B A; Choi E S; Chowdhury E H; Akaike T; Cho C S
Galactosylated chitosan-graft-poly(ethylene glycol) as hepatocyte-targeting DNA carrier.
Journal of controlled release : official journal of the Controlled Release Society 2001;76(3):349-62.
2001: Hirose S; Ise H; Uchiyama M; Cho C S; Akaike T
Regulation of asialoglycoprotein receptor expression in the proliferative state of hepatocytes.
Biochemical and biophysical research communications 2001;287(3):675-81.
2001: Kim S H; Goto M; Akaike T
Specific binding of glucose-derivatized polymers to the asialoglycoprotein receptor of mouse primary hepatocytes.
The Journal of biological chemistry 2001;276(38):35312-9.
2001: Watanabe Y; Hirakawa K; Haruyama T; Akaike T
Direct production of an activated matrix metalloproteinase-9 (gelatinase B) from mammalian cells.
FEBS letters 2001;502(1-2):63-7.
2001: Ajioka I; Nishio R; Ikekita M; Akaike T; Sasaki M; Enami J; Watanabe Y
Establishment of heterotropic liver tissue mass with direct link to the host liver following implantation of hepatocytes transfected with vascular endothelial growth factor gene in mice.
Tissue engineering 2001;7(3):335-44.
2001: Kim W J; Ishihara T; Akaike T; Maruyama A
Comb-type cationic copolymer expedites DNA strand exchange while stabilizing DNA duplex.
Chemistry (Weinheim an der Bergstrasse, Germany) 2001;7(1):176-80.
2001: Cho C S; Kobayashi A; Takei R; Ishihara T; Maruyama A; Akaike T
Receptor-mediated cell modulator delivery to hepatocyte using nanoparticles coated with carbohydrate-carrying polymers.
Biomaterials 2001;22(1):45-51.
2001: Obara K; Ishihara T; Akaike T; Maruyama A
Protein/oligonucleotide conjugates as a cell specific PNA carrier.
Nucleic acids research. Supplement (2001) 2001;(1):217-8.
2001: Kim W J; Ishihara T; Akaike T; Maruyama A
Polycation graft copolymers accelerating DNA strand exchange: involvement of ionic interaction.
Nucleic acids research. Supplement (2001) 2001;(1):151-2.
2001: Pa K H; Goto M; Miyazak J I; Cho C S; Akaike T
Incorporation of sulfonylurea into sugar-carrying polymers and their effects on insulin secretion from MIN6 cells in a solution state.
Journal of biomaterials science. Polymer edition 2001;12(8):911-20.
2000: Shibuya I; Akaike T; Watanabe Y
Design of a temporally and spatially controlled drug delivery system for the treatment of liver diseases in mice.
Hepatology (Baltimore, Md.) 2000;32(6):1300-8.
2000: Park I K; Park Y H; Shin B A; Choi E S; Kim Y R; Akaike T; Cho C S;
Galactosylated chitosan-graft-dextran as hepatocyte-targeting DNA carrier.
Journal of controlled release : official journal of the Controlled Release Society 2000;69(1):97-108.
2000: Ferdous A; Akaike T; Maruyama A
Mechanism of intermolecular purine-purine-pyrimidine triple helix stabilization by comb-type polylysine graft copolymer at physiologic potassium concentration.
Bioconjugate chemistry 2000;11(4):520-6.
2000: Haruyama T; Ajioka I; Akaike T; Watanabe Y
Regulation and significance of hepatocyte-derived matrix metalloproteinases in liver remodeling.
Biochemical and biophysical research communications 2000;272(3):681-6.
2000: Sasagawa T; Hlaing M; Akaike T
Synergistic induction of apoptosis in murine hepatoma Hepa1-6 cells by IFN-gamma and TNF-alpha.
Biochemical and biophysical research communications 2000;272(3):674-80.
2000: Watanabe Y; Ajioka I; Akaike T
[Tissue engineering: cooperation of molecular biology and polymer science]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 2000;45(8):1376-82.
2000: Kim W J; Ishihara T; Akaike T; Maruyama A
Acceleration of DNA strand exchange by polycation comb-type copolymer.
Nucleic acids symposium series 2000;(44):289-90.
2000: Ueda M; Saito M; Ishihara T; Akaike T; Maruyama A
Triplex formation using ODN conjugates with polycation comb-type copolymer.
Nucleic acids symposium series 2000;(44):209-10.
2000: Ferdous A; Akaike T; Maruyama A
Inhibition of sequence-specific protein-DNA interaction and restriction endonuclease cleavage via triplex stabilization by poly(L-lysine)-graft-dextran copolymer.
Biomacromolecules 2000;1(2):186-93.
2000: Watanabe Y; Liu X; Shibuya I; Akaike T
Functional evaluation of poly-(N-p-vinylbenzyl-O-beta-D-galactopyranosyl-[1-4]-D-gluconamide)(PVLA) as a liver specific carrier.
Journal of biomaterials science. Polymer edition 2000;11(8):833-48.
2000: Park K; Goto M; Takei R; Maruyama A; Kobayashi K; Miyazaki J; Cho C; Akaike T
Enhanced effect of sulfonylurea (SU) in copolymer comprising a sugar moiety and SU derivative as double ligands on insulin secretion from MIN6 cells.
Journal of biomaterials science. Polymer edition 2000;11(9):903-13.
1999: Park J U; Ishihara T; Kano A; Akaike T; Maruyama A
Preparation of dendritic graft copolymer consisting of poly-(L-lysine) and arabinogalactan as a hepatocyte specific DNA carrier.
Preparative biochemistry & biotechnology 1999;29(4):353-70.
1999: Maruyama A; Ferdous A; Ishihara T; Asayama S; Park J U; Nogawa M; Watanabe H; Takei Y; Akaike T
Comb-type copolymers for controlled DNA delivery.
Nucleosides & nucleotides 1999;18(6-7):1681-2.
1999: Ferdous A; Watanabe H; Akaike T; Maruyama A
Relative effects of graft copolymer and polyamines on triplex stabilization under physiological conditions.
Nucleosides & nucleotides 1999;18(6-7):1651-3.
1999: Kano A; Haruyama T; Akaike T; Watanabe Y
IRF-1 is an essential mediator in IFN-gamma-induced cell cycle arrest and apoptosis of primary cultured hepatocytes.
Biochemical and biophysical research communications 1999;257(3):672-7.
1999: Watanabe Y; Akaike T
Possible involvement of caspase-like family in maintenance of cytoskeleton integrity.
Journal of cellular physiology 1999;179(1):45-51.
1999: Asayama S; Maruyama A; Akaike T
Comb-type prepolymers consisting of a polyacrylamide backbone and poly(L-lysine) graft chains for multivalent ligands.
Bioconjugate chemistry 1999;10(2):246-53.
1999: Takei Y; Maruyama A; Kawano S; Nishimura Y; Asayama S; Nogawa M; Ikejima K; Hori M; Akaike T; Lemasters J J; Watanabe S; Sato N
Targeted gene transfer to sinusoidal endothelial cells and expression in vivo.
Transplantation proceedings 1999;31(1-2):790-1.
1999: Ajioka I; Akaike T; Watanabe Y
Expression of vascular endothelial growth factor promotes colonization, vascularization, and growth of transplanted hepatic tissues in the mouse.
Hepatology (Baltimore, Md.) 1999;29(2):396-402.
1999: Kim W J; Ishihara T; Akaike T; Maruyama A
Acceleration of DNA strand exchange by polycation comb-type copolymer.
Nucleic acids symposium series 1999;(42):139-40.
1999: Maruyama A; Saito M; Ueda M; Yamada M; Watanabe H; Akaike T
Preparation and evaluation of ODN conjugates with polycation comb-type copolymer.
Nucleic acids symposium series 1999;(42):97-8.
1998: Ferdous A; Watanabe H; Akaike T; Maruyama A
Comb-type copolymer: stabilization of triplex DNA and possible application in antigene strategy.
Journal of pharmaceutical sciences 1998;87(11):1400-5.
1998: Ferdous A; Watanabe H; Akaike T; Maruyama A
Poly(L-lysine)-graft-dextran copolymer: amazing effects on triplex stabilization under physiological pH and ionic conditions (in vitro).
Nucleic acids research 1998;26(17):3949-54.
1998: Asayama S; Nogawa M; Takei Y; Akaike T; Maruyama A
Synthesis of novel polyampholyte comb-type copolymers consisting of a poly(L-lysine) backbone and hyaluronic acid side chains for a DNA carrier.
Bioconjugate chemistry 1998;9(4):476-81.
1998: Maruyama A; Watanabe H; Ferdous A; Katoh M; Ishihara T; Akaike T
Characterization of interpolyelectrolyte complexes between double-stranded DNA and polylysine comb-type copolymers having hydrophilic side chains.
Bioconjugate chemistry 1998;9(2):292-9.
1997: Asayama S; Maruyama A; Cho C S; Akaike T
Design of comb-type polyamine copolymers for a novel pH-sensitive DNA carrier.
Bioconjugate chemistry 1997;8(6):833-8.
1997: Watanabe Y; Osaki H; Akaike T
TNF-alpha bifunctionally induces proliferation in primary hepatocytes: role of cell anchorage and spreading.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(10):4840-7.
1997: Maruyama A; Ishihara T; Kim J S; Kim S W; Akaike T
Nanoparticle DNA carrier with poly(L-lysine) grafted polysaccharide copolymer and poly(D,L-lactic acid).
Bioconjugate chemistry 1997;8(5):735-42.
1997: Park K H; Takei R; Goto M; Maruyama A; Kobayashi A; Kobayashi K; Akaike T
Specific interaction between erythrocytes and a glucose-carrying polymer mediated by the type-1 glucose transporter (GLUT-1) on the cell membrane.
Journal of biochemistry 1997;121(6):997-1001.
1997: Kano A; Watanabe Y; Takeda N; Aizawa S; Akaike T
Analysis of IFN-gamma-induced cell cycle arrest and cell death in hepatocytes.
Journal of biochemistry 1997;121(4):677-83.
1997: Maruyama A; Katoh M; Ishihara T; Akaike T
Comb-type polycations effectively stabilize DNA triplex.
Bioconjugate chemistry 1997;8(1):3-6.
1997: Ferdous A; Watanabe H; Maruyama A; Akaike T
Poly(L-lysine)-graft-dextran copolymer is a novel stabilizer of triplex DNA(II): potassium-insensitive triplex formation.
Nucleic acids symposium series 1997;(37):301-2.
1997: Maruyama A; Watanabe H; Ferdous A; Akaike T
Poly(L-lysine)-graft-dextran copolymer is a novel stabilizer of triplex DNA (I): stabilization of poly(dA).2poly(dT) triplex.
Nucleic acids symposium series 1997;(37):225-6.

Sign-in to see more

Sign-in free and Explore the Exciting World of BiomedExperts:

NetworkView

Toshihiro Akaike

Research Profile (preview)

Chemicals & Drugs

Living Beings

Anatomy

Physiology

Network (preview)

Publications

Sign in free and see...

Visualized networks:

GeoTargeted Searches:

Research Profiles:

Geonetwork of Toshihiro Akaike (preview)

All Publications