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Friedrich Würgler

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.8 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Procedures

Chemicals & Drugs

Living Beings

Physiology

Anatomy

Wing

Concepts & Ideas

Mitosis

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Co-Publications
Name
10
Graf, Ulrich
8
Albertini, Silvio
5
Eugster, Hans-Pietro
3
Sengstag, Christian
2
Guzmán Rincón, J
2
Frei, HJ
1
Spanó, Mário Antônio
1
Sun, Mingzeng
1
Zimmermann, FK
1
Fasullo, Michael
1
Certa, Ulrich

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Publications

TOP 3
Keller-Seitz Monika U; Certa Ulrich; Sengstag Christian; Würgler Friedrich E; Sun Mingzeng; Fasullo Michael
Transcriptional response of yeast to aflatoxin B1: recombinational repair involving RAD51 and RAD1.
Spanó M A; Frei H; Würgler F E; Graf U
Recombinagenic activity of four compounds in the standard and high bioactivation crosses of Drosophila melanogaster in the wing spot test.
Graf U; Abraham S K; Guzmán-Rincón J; Würgler F E
Antigenotoxicity studies in Drosophila melanogaster.

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All Publications

2004: Keller-Seitz Monika U; Certa Ulrich; Sengstag Christian; Würgler Friedrich E; Sun Mingzeng; Fasullo Michael
Transcriptional response of yeast to aflatoxin B1: recombinational repair involving RAD51 and RAD1.
Molecular biology of the cell 2004;15(9):4321-36.
2001: Spanó M A; Frei H; Würgler F E; Graf U
Recombinagenic activity of four compounds in the standard and high bioactivation crosses of Drosophila melanogaster in the wing spot test.
Mutagenesis 2001;16(5):385-94.
1998: Graf U; Abraham S K; Guzmán-Rincón J; Würgler F E
Antigenotoxicity studies in Drosophila melanogaster.
Mutation research 1998;402(1-2):203-9.
1997: Bärtsch S; Würgler F E; Sengstag C
A genetic system to detect mitotic recombination between repeated chromosomal sequences in Drosophila Schneider line 2 cells.
Mutation research 1997;395(1):9-27.
1997: Frei H; Würgler F E
The vicinal chloroalcohols 1,3-dichloro-2-propanol (DC2P), 3-chloro-1,2-propanediol (3CPD) and 2-chloro-1,3-propanediol (2CPD) are not genotoxic in vivo in the wing spot test of Drosophila melanogaster.
Mutation research 1997;394(1-3):59-68.
1997: Bärtsch S; Dücker K; Würgler F E; Sengstag C
Ectopic mitotic recombination in Drosophila probed with bacterial beta-galactosidase gene-based reporter transgenes.
Nucleic acids research 1997;25(19):3917-24.
1996: Frei H; Würgler F E
Induction of somatic mutation and recombination by four inhibitors of eukaryotic topoisomerases assayed in the wing spot test of Drosophila melanogaster.
Mutagenesis 1996;11(4):315-25.
1996: Graf U; Würgler F E
The somatic white-ivory eye spot test does not detect the same spectrum of genotoxic events as the wing somatic mutation and recombination test in Drosophila melanogaster.
Environmental and molecular mutagenesis 1996;27(3):219-26.
1995: Wittekindt N E; Würgler F E; Sengstag C
Targeting of heterologous membrane proteins into proliferated internal membranes in Saccharomyces cerevisiae.
Yeast (Chichester, England) 1995;11(10):913-28.
1995: Frei H; Würgler F E
Optimal experimental design and sample size for the statistical evaluation of data from somatic mutation and recombination tests (SMART) in Drosophila.
Mutation research 1995;334(2):247-58.
1995: Wittekindt N E; Würgler F E; Sengstag C
Functional expression of fused enzymes between human cytochrome P4501A1 and human NADPH-cytochrome P450 oxidoreductase in Saccharomyces cerevisiae.
DNA and cell biology 1995;14(4):273-83.
1994: Sengstag C; Würgler F E
DNA recombination induced by aflatoxin B1 activated by cytochrome P450 1A enzymes.
Molecular carcinogenesis 1994;11(4):227-35.
1994: Ehrenhofer-Murray A E; Würgler F E; Sengstag C
The Saccharomyces cerevisiae SGE1 gene product: a novel drug-resistance protein within the major facilitator superfamily.
Molecular & general genetics : MGG 1994;244(3):287-94.
1994: Ehrenhofer-Murray A E; Würgler F E; Sengstag C
Characterization of the trp5-27 allele used to monitor drug-induced mitotic gene conversion in the Saccharomyces cerevisiae tester strain D7.
Mutagenesis 1994;9(4):377-81.
1994: Sengstag C; Eugster H P; Würgler F E
High promutagen activating capacity of yeast microsomes containing human cytochrome P-450 1A and human NADPH-cytochrome P-450 reductase.
Carcinogenesis 1994;15(5):837-43.
1994: Acuña G; Würgler F E; Sengstag C
Reciprocal mitotic recombination is the predominant mechanism for the loss of a heterozygous gene in Saccharomyces cerevisiae.
Environmental and molecular mutagenesis 1994;24(4):307-16.
1993: Oppliger T; Würgler F E; Sengstag C
A plasmid system to monitor gene conversion and reciprocal recombination in vitro.
Mutation research 1993;291(3):181-92.
1993: Eugster H P; Probst M; Würgler F E; Sengstag C
Caffeine, estradiol, and progesterone interact with human CYP1A1 and CYP1A2. Evidence from cDNA-directed expression in Saccharomyces cerevisiae.
Drug metabolism and disposition: the biological fate of chemicals 1993;21(1):43-9.
1993: Albertini S; Brunner M; Würgler F E
Analysis of the six additional chemicals for in vitro assays of the European Economic Communities' EEC aneuploidy programme using Saccharomyces cerevisiae D61.M and the in vitro porcine brain tubulin assembly assay.
Environmental and molecular mutagenesis 1993;21(2):180-92.
1992: Würgler F E
International Commission for Protection against Environmental Mutagens and Carcinogens. Recombination and gene conversion.
Mutation research 1992;284(1):3-14.
1992: Schlatter J; Würgler F E; Kränzlin R; Maier P; Holliger E; Graf U
The potential genotoxicity of sorbates: effects on cell cycle in vitro in V79 cells and somatic mutations in Drosophila.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 1992;30(10):843-51.
1992: Würgler F E; Schlatter J; Maier P
The genotoxicity status of sorbic acid, potassium sorbate and sodium sorbate.
Mutation research 1992;283(2):107-11.
1992: Würgler F E; Kramers P G
Environmental effects of genotoxins (eco-genotoxicology).
Mutagenesis 1992;7(5):321-7.
1992: Frei H; Lüthy J; Brauchli J; Zweifel U; Würgler F E; Schlatter C
Structure/activity relationships of the genotoxic potencies of sixteen pyrrolizidine alkaloids assayed for the induction of somatic mutation and recombination in wing cells of Drosophila melanogaster.
Chemico-biological interactions 1992;83(1):1-22.
1992: Eugster H P; Bärtsch S; Würgler F E; Sengstag C
Functional co-expression of human oxidoreductase and cytochrome P450 1A1 in Saccharomyces cerevisiae results in increased EROD activity.
Biochemical and biophysical research communications 1992;185(2):641-7.
1992: Frei H; Clements J; Howe D; Würgler F E
The genotoxicity of the anti-cancer drug mitoxantrone in somatic and germ cells of Drosophila melanogaster.
Mutation research 1992;279(1):21-33.
1991: Würgler F E; Friederich U; Schlatter J
Lack of mutagenicity of ochratoxin A and B, citrinin, patulin and cnestine in Salmonella typhimurium TA102.
Mutation research 1991;261(3):209-16.
1991: Eugster H P; Sengstag C; Hinnen A; Meyer U A; Würgler F E
Heterologous expression of human microsomal epoxide hydrolase in Saccharomyces cerevisiae. Study of the valpromide-carbamazepine epoxide interaction.
Biochemical pharmacology 1991;42(7):1367-72.
1991: Würgler F E
Effects of chemical and physical agents on recombination events in cells of the germ line of male and female Drosophila melanogaster.
Mutation research 1991;250(1-2):275-90.
1991: Würgler F E; Kägi A
Genotoxicity testing with the somatic white-ivory system in the eye of Drosophila melanogaster.
Mutation research 1991;263(1):33-9.
1991: Grüter A; Friederich U; Würgler F E
The mutagenicity of edible mushrooms in a histidine-independent bacterial test system.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 1991;29(3):159-65.
1991: Brunner M; Albertini S; Würgler F E
Effects of 10 known or suspected spindle poisons in the in vitro porcine brain tubulin assembly assay.
Mutagenesis 1991;6(1):65-70.
1990: Tripathy N K; Würgler F E; Frei H
Genetic toxicity of six carcinogens and six non-carcinogens in the Drosophila wing spot test.
Mutation research 1990;242(3):169-80.
1990: Eugster H P; Sengstag C; Meyer U A; Hinnen A; Würgler F E
Constitutive and inducible expression of human cytochrome P450IA1 in yeast Saccharomyces cerevisiae: an alternative enzyme source for in vitro studies.
Biochemical and biophysical research communications 1990;172(2):737-44.
1990: Buzzi R; Würgler F E
Knowledge-based battery design of short-term tests based on dose information.
Mutation research 1990;234(5):269-88.
1990: Grüter A; Friederich U; Würgler F E
Antimutagenic effects of mushrooms.
Mutation research 1990;231(2):243-9.
1990: Frölich A; Würgler F E
Genotoxicity of ethyl carbamate in the Drosophila wing spot test: dependence on genotype-controlled metabolic capacity.
Mutation research 1990;244(3):201-8.
1990: Würgler F E; Friederich U; Fürer E; Ganss M
Salmonella/mammalian microsome assay with tetranitromethane and 3-nitro-L-tyrosine.
Mutation research 1990;244(1):7-14.
1990: Frölich A; Würgler F E
Drosophila wing-spot test: improved detectability of genotoxicity of polycyclic aromatic hydrocarbons.
Mutation research 1990;234(2):71-80.
1990: Guzmán Rincón J; Würgler F E; Vogel E W
Training course on Drosophila somatic genotoxicity assays in Mexico.
Mutation research 1990;234(2):107-9.
1990: Würgler F E
Recombination and gene conversion: an overview.
Progress in clinical and biological research 1990;340A():113-9.
1989: Frölich A; Würgler F E
New tester strains with improved bioactivation capacity for the Drosophila wing-spot test.
Mutation research 1989;216(3):179-87.
1989: Graf U; Frei H; Kägi A; Katz A J; Würgler F E
Thirty compounds tested in the Drosophila wing spot test.
Mutation research 1989;222(4):359-73.
1989: Albertini S; Friederich U; Würgler F E
Reversible inhibition of mammalian tubulin assembly in vitro and effects in Saccharomyces cerevisiae D61.M by mitomycin C.
Mutagenesis 1989;4(1):39-44.
1988: Albertini S; Friederich U; Holderegger C; Würgler F E
The in vitro porcine brain tubulin assembly assay: effects of a genotoxic carcinogen (aflatoxin B1), eight tumor promoters and nine miscellaneous substances.
Mutation research 1988;201(2):283-92.
1988: Frei H; Würgler F E
Statistical methods to decide whether mutagenicity test data from Drosophila assays indicate a positive, negative, or inconclusive result.
Mutation research 1988;203(4):297-308.
1988: Albertini S; Friederich U; Würgler F E
Induction of mitotic chromosome loss in the diploid yeast Saccharomyces cerevisiae D61.M by genotoxic carcinogens and tumor promoters.
Environmental and molecular mutagenesis 1988;11(4):497-508.
1986: Niggli B; Friederich U; Hann D; Würgler F E
Endogenous promutagen activation in the yeast Saccharomyces cerevisiae: factors influencing aflatoxin B1 mutagenicity.
Mutation research 1986;175(4):223-9.
1985: Albertini S; Friederich U; Gröschel-Stewart U; Zimmermann F K; Würgler F E
Phenobarbital induces aneuploidy in Saccharomyces cerevisiae and stimulates the assembly of porcine brain tubulin.
Mutation research 1985;144(2):67-71.
1985: Albertini S; Friederich U; Schlatter C; Würgler F E
The influence of roasting procedure on the formation of mutagenic compounds in coffee.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 1985;23(6):593-7.
1985: Friederich U; Hann D; Albertini S; Schlatter C; Würgler F E
Mutagenicity studies on coffee. The influence of different factors on the mutagenic activity in the Salmonella/mammalian microsome assay.
Mutation research 1985;156(1-2):39-52.
1985: Frei H; Würgler F E; Juon H; Hall C B; Graf U
Aristolochic acid is mutagenic and recombinogenic in Drosophila genotoxicity tests.
Archives of toxicology 1985;56(3):158-66.
1984: Graf U; Würgler F E; Katz A J; Frei H; Juon H; Hall C B; Kale P G
Somatic mutation and recombination test in Drosophila melanogaster.
Environmental mutagenesis 1984;6(2):153-88.
1983: Würgler F E; Graf U; Frei H; Juon H
Genotoxic activity of the anti-cancer drug methotrexate in somatic cells of Drosophila melanogaster.
Mutation research 1983;122(3-4):321-8.
1983: Graf U; Juon H; Katz A J; Frei H J; Würgler F E
A pilot study on a new Drosophila spot test.
Mutation research 1983;120(4):233-9.
1982: Graf U; Kägi A; Würgler F E
Mutagenesis in spermatozoa of Drosophila melanogaster by cross-linking agents depends on the mus(1)101+ gene product in the oocyte.
Mutation research 1982;95(2-3):237-49.
1982: Friederich U; Aeschbacher H U; Seiler J P; Würgler F E
The Salmonella/microsome assay: some possible causes for interlaboratory variations.
Mutation research 1982;103(2):133-20.

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