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Richard Wurtman

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
14
Slack, Barbara
14
Ulus, Ismail
13
Nitsch, Roger
13
Growdon, John
10
Cansev, Mehmet
10
Zhdanova, Irina
8
Blusztajn, Jan Krzysztof
8
Teather, Lisa
6
Balcioglu, A
5
Caballero, Benjamin
5
Kaakkola, Seppo
5
Wang, Lei
5
Watkins, Carol
5
Pooler, Amy
5
Acworth, Ian

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Publications

TOP 3
Wurtman Richard J; Cansev Mehmet; Sakamoto Toshimasa; Ulus Ismail H
Use of phosphatide precursors to promote synaptogenesis.
Cansev Mehmet; Marzloff George; Sakamoto Toshimasa; Ulus Ismail H; Wurtman Richard J
Giving uridine and/or docosahexaenoic acid orally to rat dams during gestation and nursing increases synaptic elements in brains of weanling pups.
Wurtman Richard J; Cansev Mehmet; Sakamoto Toshimasa; Ulus Ismail H
Administration of docosahexaenoic acid, uridine and choline increases levels of synaptic membranes and dendritic spines in rodent brain.

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All Publications

2009: Wurtman Richard J; Cansev Mehmet; Sakamoto Toshimasa; Ulus Ismail H
Use of phosphatide precursors to promote synaptogenesis.
Annual review of nutrition 2009;29():59-87.
2009: Cansev Mehmet; Marzloff George; Sakamoto Toshimasa; Ulus Ismail H; Wurtman Richard J
Giving uridine and/or docosahexaenoic acid orally to rat dams during gestation and nursing increases synaptic elements in brains of weanling pups.
Developmental neuroscience 2009;31(3):181-92.
2009: Wurtman Richard J; Cansev Mehmet; Sakamoto Toshimasa; Ulus Ismail H
Administration of docosahexaenoic acid, uridine and choline increases levels of synaptic membranes and dendritic spines in rodent brain.
World review of nutrition and dietetics 2009;99():71-96.
2008: Cansev Mehmet; Ulus Ismail H; Wang Lei; Maher Timothy J; Wurtman Richard J
Restorative effects of uridine plus docosahexaenoic acid in a rat model of Parkinson's disease.
Neuroscience research 2008;62(3):206-9.
2008: Wurtman Richard J
Synapse formation and cognitive brain development: effect of docosahexaenoic acid and other dietary constituents.
Metabolism: clinical and experimental 2008;57 Suppl 2():S6-10.
2008: Cansev Mehmet; Wurtman Richard J; Sakamoto Toshimasa; Ulus Ismail H
Oral administration of circulating precursors for membrane phosphatides can promote the synthesis of new brain synapses.
Alzheimer's & dementia : the journal of the Alzheimer's Association 2008;4(1 Suppl 1):S153-68.
2007: Sakamoto Toshimasa; Cansev Mehmet; Wurtman Richard J
Oral supplementation with docosahexaenoic acid and uridine-5'-monophosphate increases dendritic spine density in adult gerbil hippocampus.
Brain research 2007;1182():50-9.
2007: Cansev M; Wurtman R J
Chronic administration of docosahexaenoic acid or eicosapentaenoic acid, but not arachidonic acid, alone or in combination with uridine, increases brain phosphatide and synaptic protein levels in gerbils.
Neuroscience 2007;148(2):421-31.
2007: Richardson U Ingrid; Wurtman Richard J
Polyunsaturated fatty acids stimulate phosphatidylcholine synthesis in PC12 cells.
Biochimica et biophysica acta 2007;1771(4):558-63.
2007: Wang Lei; Maher Timothy J; Wurtman Richard J
Oral L-glutamine increases GABA levels in striatal tissue and extracellular fluid.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007;21(4):1227-32.
2007: Wang Lei; Albrecht Meredith A; Wurtman Richard J
Dietary supplementation with uridine-5'-monophosphate (UMP), a membrane phosphatide precursor, increases acetylcholine level and release in striatum of aged rat.
Brain research 2007;1133(1):42-8.
2006: Teather Lisa A; Wurtman Richard J
Chronic administration of UMP ameliorates the impairment of hippocampal-dependent memory in impoverished rats.
The Journal of nutrition 2006;136(11):2834-7.
2006: Wurtman Richard J
Narcolepsy and the hypocretins.
Metabolism: clinical and experimental 2006;55(10 Suppl 2):S36-9.
2006: Wurtman Richard
Ramelteon: a novel treatment for the treatment of insomnia.
Expert review of neurotherapeutics 2006;6(7):957-64.
2006: Ulus Ismail H; Watkins Carol J; Cansev Mehmet; Wurtman Richard J
Cytidine and uridine increase striatal CDP-choline levels without decreasing acetylcholine synthesis or release.
Cellular and molecular neurobiology 2006;26(4-6):563-77.
2006: Teather Lisa A; Afonso Veronica M; Wurtman Richard J
Inhibition of platelet-activating factor receptors in hippocampal plasma membranes attenuates the inflammatory nociceptive response in rats.
Brain research 2006;1097(1):230-3.
2006: Wurtman Richard J; Ulus Ismail H; Cansev Mehmet; Watkins Carol J; Wang Lei; Marzloff George
Synaptic proteins and phospholipids are increased in gerbil brain by administering uridine plus docosahexaenoic acid orally.
Brain research 2006;1088(1):83-92.
2006: Pooler Amy M; Xi Shijun C; Wurtman Richard J
The 3-hydroxy-3-methylglutaryl co-enzyme A reductase inhibitor pravastatin enhances neurite outgrowth in hippocampal neurons.
Journal of neurochemistry 2006;97(3):716-23.
2005: Cansev Mehmet; Watkins Carol J; van der Beek Eline M; Wurtman Richard J
Oral uridine-5'-monophosphate (UMP) increases brain CDP-choline levels in gerbils.
Brain research 2005;1058(1-2):101-8.
2005: Wurtman Richard J
Genes, stress, and depression.
Metabolism: clinical and experimental 2005;54(5 Suppl 1):16-9.
2005: Brzezinski Amnon; Vangel Mark G; Wurtman Richard J; Norrie Gillian; Zhdanova Irina; Ben-Shushan Abraham; Ford Ian
Effects of exogenous melatonin on sleep: a meta-analysis.
Sleep medicine reviews 2005;9(1):41-50.
2005: Teather Lisa A; Wurtman Richard J
Dietary CDP-choline supplementation prevents memory impairment caused by impoverished environmental conditions in rats.
Learning & memory (Cold Spring Harbor, N.Y.) 2005;12(1):39-43.
2005: Wang Lei; Pooler Amy M; Albrecht Meredith A; Wurtman Richard J
Dietary uridine-5'-monophosphate supplementation increases potassium-evoked dopamine release and promotes neurite outgrowth in aged rats.
Journal of molecular neuroscience : MN 2005;27(1):137-45.
2005: Pooler A M; Guez D H; Benedictus R; Wurtman R J
Uridine enhances neurite outgrowth in nerve growth factor-differentiated PC12 [corrected]
Neuroscience 2005;134(1):207-14.
2004: Arjona Anibal A; Zhang Sandy X; Adamson Brittany; Wurtman Richard J
An animal model of antipsychotic-induced weight gain.
Behavioural brain research 2004;152(1):121-7.
2004: Pooler Amy M; Arjona Anibal A; Lee Robert K; Wurtman Richard J
Prostaglandin E2 regulates amyloid precursor protein expression via the EP2 receptor in cultured rat microglia.
Neuroscience letters 2004;362(2):127-30.
2004: Wang Ping; Saraswati Sudipta; Guan Zhuo; Watkins Carol J; Wurtman Richard J; Littleton J Troy
A Drosophila temperature-sensitive seizure mutant in phosphoglycerate kinase disrupts ATP generation and alters synaptic function.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(19):4518-29.
2004: Amer Ahmed; Breu Jeff; McDermott Janine; Wurtman Richard J; Maher Timothy J
5-Hydroxy-L-tryptophan suppresses food intake in food-deprived and stressed rats.
Pharmacology, biochemistry, and behavior 2004;77(1):137-43.
2003: Teather Lisa A; Wurtman Richard J
Dietary cytidine (5')-diphosphocholine supplementation protects against development of memory deficits in aging rats.
Progress in neuro-psychopharmacology & biological psychiatry 2003;27(4):711-7.
2003: Richardson U Ingrid; Watkins Carol J; Pierre Celine; Ulus Ismael H; Wurtman Richard J
Stimulation of CDP-choline synthesis by uridine or cytidine in PC12 rat pheochromocytoma cells.
Brain research 2003;971(2):161-7.
2003: Teather Lisa A; Wurtman Richard J
Cyclooxygenase-2 mediates platelet-activating factor-induced prostaglandin E2 release from rat primary astrocytes.
Neuroscience letters 2003;340(3):177-80.
2003: Wurtman Richard J; Wurtman Judith J; Regan Meredith M; McDermott Janine M; Tsay Rita H; Breu Jeff J
Effects of normal meals rich in carbohydrates or proteins on plasma tryptophan and tyrosine ratios.
The American journal of clinical nutrition 2003;77(1):128-32.
2002: Teather Lisa A; Magnusson Jane E; Chow Christina M; Wurtman Richard J
Environmental conditions influence hippocampus-dependent behaviours and brain levels of amyloid precursor protein in rats.
The European journal of neuroscience 2002;16(12):2405-15.
2002: Teather Lisa A; Magnusson Jane E; Wurtman Richard J
Platelet-activating factor antagonists decrease the inflammatory nociceptive response in rats.
Psychopharmacology 2002;163(3-4):430-3.
2002: Arjona Anibal A; Pooler Amy M; Lee Robert K; Wurtman Richard J
Effect of a 5-HT(2C) serotonin agonist, dexnorfenfluramine, on amyloid precursor protein metabolism in guinea pigs.
Brain research 2002;951(1):135-40.
2002: Teather Lisa A; Lee Robert K K; Wurtman Richard J
Platelet-activating factor increases prostaglandin E(2) release from astrocyte-enriched cortical cell cultures.
Brain research 2002;946(1):87-95.
2002: Wurtman Richard J
Stress and the adrenocortical control of epinephrine synthesis.
Metabolism: clinical and experimental 2002;51(6 Suppl 1):11-4.
2002: Wurtman Judith J; McDermott Janine M; Levendusky Philip; Duca Karen; Wurtman Richard
The effect of a novel dietary intervention on weight loss in psychotropic drug-induced obesity.
Psychopharmacology bulletin 2002;36(3):55-9.
2001: Zhdanova I V; Wurtman R J; Regan M M; Taylor J A; Shi J P; Leclair O U
Melatonin treatment for age-related insomnia.
The Journal of clinical endocrinology and metabolism 2001;86(10):4727-30.
2000: Wurtman R J; Regan M; Ulus I; Yu L
Effect of oral CDP-choline on plasma choline and uridine levels in humans.
Biochemical pharmacology 2000;60(7):989-92.
2000: Balcioglu A; Wurtman R J
Sibutramine, a serotonin uptake inhibitor, increases dopamine concentrations in rat striatal and hypothalamic extracellular fluid.
Neuropharmacology 2000;39(12):2352-9.
2000: Balcioglu A; Wurtman R J
Striatal serotonin receptors and dopamine release.
Journal of neurochemistry 2000;75(2):886.
2000: Ulus I H; Maher T J; Wurtman R J
Characterization of phentermine and related compounds as monoamine oxidase (MAO) inhibitors.
Biochemical pharmacology 2000;59(12):1611-21.
2000: Wang C; Wurtman R J; Lee R K
Amyloid precursor protein and membrane phospholipids in primary cortical neurons increase with development, or after exposure to nerve growth factor or Abeta(1-40).
Brain research 2000;865(2):157-67.
1999: Wurtman R J
[Neuronal death mechanisms in cerebral ischemia: laboratory at the clinic]
Revista de neurologia 1999;29(6):524-6.
1999: Young M J; Lee R K; Jhaveri S; Wurtman R J
Intracellular and cell-surface distribution of amyloid precursor protein in cortical astrocytes.
Brain research bulletin 1999;50(1):27-32.
1999: Li J; Wurtman R J
Heterogeneous long chain acyl-CoA synthetases control distribution of individual fatty acids in newly-formed glycerolipids of neuronal cells undergoing neurite outgrowth.
Neurochemical research 1999;24(6):739-50.
1999: Knapp S; Wurtman R J
Enhancement of free fatty acid incorporation into phospholipids by choline plus cytidine.
Brain research 1999;822(1-2):52-9.
1999: Li J; Wurtman R J
Mechanisms whereby nerve growth factor increases diacylglycerol levels in differentiating PC12 cells.
Brain research 1999;818(2):252-9.
1999: Zhdanova I V; Wurtman R J; Wagstaff J
Effects of a low dose of melatonin on sleep in children with Angelman syndrome.
Journal of pediatric endocrinology & metabolism : JPEM 1999;12(1):57-67.
1999: Maher T J; Ulus I H; Wurtman R J
Phentermine and other monoamine-oxidase inhibitors may increase plasma serotonin when given with fenfluramines.
Lancet 1999;353(9146):38.
1998: Balcioglu A; Wurtman R J
Effects of fenfluramine and phentermine (fen-phen) on dopamine and serotonin release in rat striatum: in vivo microdialysis study in conscious animals.
Brain research 1998;813(1):67-72.
1998: Li J; Wurtman R J
Nerve growth factor stimulates diacylglycerol de novo synthesis and phosphatidylinositol hydrolysis in pheochromocytoma cells.
Brain research 1998;803(1-2):44-53.
1998: Zhdanova I V; Wurtman R J; Balcioglu A; Kartashov A I; Lynch H J
Endogenous melatonin levels and the fate of exogenous melatonin: age effects.
The journals of gerontology. Series A, Biological sciences and medical sciences 1998;53(4):B293-8.
1998: Araki W; Wurtman R J
Increased expression of amyloid precursor protein and amyloid precursor-like protein 2 during trophic factor withdrawal-induced death of neuronal PC12 cells.
Brain research. Molecular brain research 1998;56(1-2):169-77.
1998: Balcioglu A; Wurtman R J
Effects of phentermine on striatal dopamine and serotonin release in conscious rats: in vivo microdialysis study.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 1998;22(4):325-8.
1998: Araki W; Wurtman R J
How is membrane phospholipid biosynthesis controlled in neural tissues?
Journal of neuroscience research 1998;51(6):667-74.
1998: Balcioglu A; Wurtman R J
Dexfenfluramine enhances striatal dopamine release in conscious rats via a serotoninergic mechanism.
The Journal of pharmacology and experimental therapeutics 1998;284(3):991-7.
1998: Zhdanova I V; Cantor M L; Leclair O U; Kartashov A I; Wurtman R J
Behavioral effects of melatonin treatment in non-human primates.
Sleep research online : SRO 1998;1(3):114-8.
1997: Zhdanova I V; Wurtman R J
Efficacy of melatonin as a sleep-promoting agent.
Journal of biological rhythms 1997;12(6):644-50.
1997: Zhdanova I V; Lynch H J; Wurtman R J
Melatonin: a sleep-promoting hormone.
Sleep 1997;20(10):899-907.
1997: Slack B E; Breu J; Muchnicki L; Wurtman R J
Rapid stimulation of amyloid precursor protein release by epidermal growth factor: role of protein kinase C.
The Biochemical journal 1997;327 ( Pt 1)():245-9.
1997: Araki W; Wurtman R J
Control of membrane phosphatidylcholine biosynthesis by diacylglycerol levels in neuronal cells undergoing neurite outgrowth.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(22):11946-50.
1997: Erfurth A; Wurtman R J
Sensitive measurement of agonist-stimulated [3H]inositol monophosphate accumulation in rat cortical miniprisms.
Brain research. Brain research protocols 1997;1(2):139-44.
1997: Lee R K; Araki W; Wurtman R J
Stimulation of amyloid precursor protein synthesis by adrenergic receptors coupled to cAMP formation.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(10):5422-6.
1997: Lee R K; Wurtman R J
Metabotropic glutamate receptors increase amyloid precursor protein processing in astrocytes: inhibition by cyclic AMP.
Journal of neurochemistry 1997;68(5):1830-5.
1997: Ulus I H; Wurtman R J
Metabotropic glutamate receptor agonists increase release of soluble amyloid precursor protein derivatives from rat brain cortical and hippocampal slices.
The Journal of pharmacology and experimental therapeutics 1997;281(1):149-54.
1997: Bogdanov M B; Wurtman R J
Possible involvement of nitric oxide in NMDA-induced glutamate release in the rat striatum: an in vivo microdialysis study.
Neuroscience letters 1997;221(2-3):197-201.
1996: Petryniak M A; Wurtman R J; Slack B E
Elevated intracellular calcium concentration increases secretory processing of the amyloid precursor protein by a tyrosine phosphorylation-dependent mechanism.
The Biochemical journal 1996;320 ( Pt 3)():957-63.
1996: Bogdanov M B; Tjurmina O A; Wurtman R J
Consumption of a high dietary dose of monosodium glutamate fails to affect extracellular glutamate levels in the hypothalamic arcuate nucleus of adult rats.
Brain research 1996;736(1-2):76-81.
1996: Zhdanova I V; Wurtman R J; Morabito C; Piotrovska V R; Lynch H J
Effects of low oral doses of melatonin, given 2-4 hours before habitual bedtime, on sleep in normal young humans.
Sleep 1996;19(5):423-31.
1996: Farber S A; Savci V; Wei A; Slack B E; Wurtman R J
Choline's phosphorylation in rat striatal slices is regulated by the activity of cholinergic neurons.
Brain research 1996;723(1-2):90-9.
1996: Spiers P A; Myers D; Hochanadel G S; Lieberman H R; Wurtman R J
Citicoline improves verbal memory in aging.
Archives of neurology 1996;53(5):441-8.
1996: Marshall D L; De Micheli E; Bogdanov M B; Wurtman R J
Effects of ethanolamine (Etn) administration on Etn and choline (Ch) levels in plasma, brain extracellular fluid (ECF) and brain tissue, and on brain phospholipid levels in rats: an in vivo study.
Neuroscience research communications 1996;18(2):87-96.
1996: Nitsch R M; Deng M; Growdon J H; Wurtman R J
Serotonin 5-HT2a and 5-HT2c receptors stimulate amyloid precursor protein ectodomain secretion.
The Journal of biological chemistry 1996;271(8):4188-94.
1996: Lee R K; Jimenez J; Cox A J; Wurtman R J
Metabotropic glutamate receptors regulate APP processing in hippocampal neurons and cortical astrocytes derived from fetal rats.
Annals of the New York Academy of Sciences 1996;777():338-43.
1996: Nitsch R M; Wurtman R J; Growdon J H
Regulation of APP processing. Potential for the therapeutical reduction of brain amyloid burden.
Annals of the New York Academy of Sciences 1996;777():175-82.
1995: Spring B; Wurtman J; Wurtman R; el-Khoury A; Goldberg H; McDermott J; Pingitore R
Efficacies of dexfenfluramine and fluoxetine in preventing weight gain after smoking cessation.
The American journal of clinical nutrition 1995;62(6):1181-7.
1995: Wurtman R J; Wurtman J J
Brain serotonin, carbohydrate-craving, obesity and depression.
Obesity research 1995;3 Suppl 4():477S-480S.
1995: Farber S A; Nitsch R M; Schulz J G; Wurtman R J
Regulated secretion of beta-amyloid precursor protein in rat brain.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1995;15(11):7442-51.
1995: Lee R K; Wurtman R J; Cox A J; Nitsch R M
Amyloid precursor protein processing is stimulated by metabotropic glutamate receptors.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(17):8083-7.
1995: Zhdanova I V; Wurtman R J; Lynch H J; Ives J R; Dollins A B; Morabito C; Matheson J K; Schomer D L
Sleep-inducing effects of low doses of melatonin ingested in the evening.
Clinical pharmacology and therapeutics 1995;57(5):552-8.
1995: Slack B E; Breu J; Petryniak M A; Srivastava K; Wurtman R J
Tyrosine phosphorylation-dependent stimulation of amyloid precursor protein secretion by the m3 muscarinic acetylcholine receptor.
The Journal of biological chemistry 1995;270(14):8337-44.
1995: Dollins A B; Krock L P; Storm W F; Wurtman R J; Lieberman H R
L-tyrosine ameliorates some effects of lower body negative pressure stress.
Physiology & behavior 1995;57(2):223-30.
1995: Slack B E; Breu J; Livneh E; Eldar H; Wurtman R J
Phorbol ester stimulates choline uptake in Swiss 3T3 fibroblasts following introduction of the gene encoding protein kinase C alpha.
The Biochemical journal 1995;305 ( Pt 2)():621-6.
1995: Savci V; Wurtman R J
Effect of cytidine on membrane phospholipid synthesis in rat striatal slices.
Journal of neurochemistry 1995;64(1):378-84.
1995: Jackson D A; Kischka U; Wurtman R J
Choline enhances scopolamine-induced acetylcholine release in dorsal hippocampus of conscious, freely-moving rats.
Life sciences 1995;56(1):45-9.
1994: Erfurth A; Gardier A M; Ribeiro E; Wurtman R J
Effects of subchronic pretreatment with D-fenfluramine or p-chloroamphetamine on [3H]inositolmonophosphate accumulation in rat cortical miniprisms.
Brain research 1994;665(1):107-14.
1994: O'Rourke D A; Wurtman J J; Wurtman R J; Tsay R; Gleason R; Baer L; Jenike M A
Aberrant snacking patterns and eating disorders in patients with obsessive compulsive disorder.
The Journal of clinical psychiatry 1994;55(10):445-7.
1994: Bogdanov M B; Wurtman R J
Effects of systemic or oral ad libitum monosodium glutamate administration on striatal glutamate release, as measured using microdialysis in freely moving rats.
Brain research 1994;660(2):337-40.
1994: Dollins A B; Zhdanova I V; Wurtman R J; Lynch H J; Deng M H
Effect of inducing nocturnal serum melatonin concentrations in daytime on sleep, mood, body temperature, and performance.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(5):1824-8.
1994: Nitsch R M; Slack B E; Farber S A; Schulz J G; Deng M; Kim C; Borghesani P R; Korver W; Wurtman R J; Growdon J H
Regulation of proteolytic processing of the amyloid beta-protein precursor of Alzheimer's disease in transfected cell lines and in brain slices.
Journal of neural transmission. Supplementum 1994;44():21-7.
1993: Marshall D L; Wurtman R J
Effect of choline on basal and stimulated acetylcholine release: an in vivo microdialysis study using a low neostigmine concentration.
Brain research 1993;629(2):269-74.
1993: Wurtman J; Wurtman R; Berry E; Gleason R; Goldberg H; McDermott J; Kahne M; Tsay R
Dexfenfluramine, fluoxetine, and weight loss among female carbohydrate cravers.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1993;9(3):201-10.
1993: Slack B E; Nitsch R M; Livneh E; Kunz G M; Breu J; Eldar H; Wurtman R J
Regulation by phorbol esters of amyloid precursor protein release from Swiss 3T3 fibroblasts overexpressing protein kinase C alpha.
The Journal of biological chemistry 1993;268(28):21097-101.
1993: Nitsch R M; Blusztajn J K; Doyle F M; Robitaille Y; Wurtman R J; Growdon J H; Kish S J
Phospholipid metabolite levels are altered in cerebral cortex of patients with dominantly inherited olivopontocerebellar atrophy.
Neuroscience letters 1993;161(2):191-4.
1993: Ribeiro E B; Bettiker R L; Bogdanov M; Wurtman R J
Effects of systemic nicotine on serotonin release in rat brain.
Brain research 1993;621(2):311-8.
1993: Agut J; Lopez G-Coviella I; Ortiz J A; Wurtman R J
Oral cytidine 5'-diphosphate choline administration to rats increases brain phospholipid levels.
Annals of the New York Academy of Sciences 1993;695():318-20.
1993: Holmes T C; Nitsch R M; Erfurth A; Wurtman R J
Phospholipid and phospholipid metabolites in rat frontal cortex are decreased following nucleus basalis lesions.
Annals of the New York Academy of Sciences 1993;695():241-3.
1993: Slack B E; Nitsch R M; Livneh E; Kunz G M; Eldar H; Wurtman R J
Regulation of amyloid precursor protein release by protein kinase C in Swiss 3T3 fibroblasts.
Annals of the New York Academy of Sciences 1993;695():128-31.
1993: Nitsch R M; Slack B E; Farber S A; Borghesani P R; Schulz J G; Kim C; Felder C C; Growdon J H; Wurtman R J
Receptor-coupled amyloid precursor protein processing.
Annals of the New York Academy of Sciences 1993;695():122-7.
1993: Nitsch R M; Farber S A; Growdon J H; Wurtman R J
Release of amyloid beta-protein precursor derivatives by electrical depolarization of rat hippocampal slices.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(11):5191-3.
1993: Kischka U; Farber S A; Marshall D; Wurtman R J
Carbachol and naloxone synergistically elevate dopamine release in rat striatum: an in vivo microdialysis study.
Brain research 1993;613(2):288-90.
1993: Farber S A; Kischka U; Marshall D L; Wurtman R J
Potentiation by choline of basal and electrically evoked acetylcholine release, as studied using a novel device which both stimulates and perfuses rat corpus striatum.
Brain research 1993;607(1-2):177-84.
1993: Dollins A B; Lynch H J; Wurtman R J; Deng M H; Lieberman H R
Effects of illumination on human nocturnal serum melatonin levels and performance.
Physiology & behavior 1993;53(1):153-60.
1993: Kaakkola S; Wurtman R J
Effects of catechol-O-methyltransferase inhibitors and L-3,4-dihydroxyphenylalanine with or without carbidopa on extracellular dopamine in rat striatum.
Journal of neurochemistry 1993;60(1):137-44.
1993: Dollins A B; Lynch H J; Wurtman R J; Deng M H; Kischka K U; Gleason R E; Lieberman H R
Effect of pharmacological daytime doses of melatonin on human mood and performance.
Psychopharmacology 1993;112(4):490-6.
1993: Kaakkola S; Wurtman R J
Effects of two diketopiperazines, cyclo (His-Pro) and cyclo (Asp-Phe), on striatal dopamine: a microdialysis study.
Brain research bulletin 1993;32(6):667-72.
1992: Conlay L A; Sabounjian L A; Wurtman R J
Exercise and neuromodulators: choline and acetylcholine in marathon runners.
International journal of sports medicine 1992;13 Suppl 1():S141-2.
1992: Nitsch R M; Slack B E; Wurtman R J; Growdon J H
Release of Alzheimer amyloid precursor derivatives stimulated by activation of muscarinic acetylcholine receptors.
Science (New York, N.Y.) 1992;258(5080):304-7.
1992: Gardier A M; Kaakkola S; Erfurth A; Wurtman R J
Effects of methiothepin on changes in brain serotonin release induced by repeated administration of high doses of anorectic serotoninergic drugs.
Brain research 1992;588(1):67-74.
1992: Kaakkola S; Wurtman R J
Effects of COMT inhibitors on striatal dopamine metabolism: a microdialysis study.
Brain research 1992;587(2):241-9.
1992: Richardson U I; Wurtman R J
Base-exchange and cell growth in 3T6 mouse fibroblasts.
Biochimica et biophysica acta 1992;1127(1):99-102.
1992: G-Coviella I L; Wurtman R J
Enhancement by cytidine of membrane phospholipid synthesis.
Journal of neurochemistry 1992;59(1):338-43.
1992: Slack B E; Richardson U I; Nitsch R M; Wurtman R J
Dioctanoylglycerol stimulates accumulation of [methyl-14C]choline and its incorporation into acetylcholine and phosphatidylcholine in a human cholinergic neuroblastoma cell line.
Brain research 1992;585(1-2):169-76.
1992: López G-Coviella I; Agut J; Ortiz J A; Wurtman R J
Effects of orally administered cytidine 5'-diphosphate choline on brain phospholipid content.
The Journal of nutritional biochemistry 1992;3(6):313-5.
1992: Ulus I H; Buyukuysal R L; Wurtman R J
N-methyl-D-aspartate increases acetylcholine release from rat striatum and cortex: its effect is augmented by choline.
The Journal of pharmacology and experimental therapeutics 1992;261(3):1122-8.
1992: Richardson U I; Wurtman R J
Characterization of [3H]MK-801 binding in LA-N-2 neuroblastoma cells.
Annals of the New York Academy of Sciences 1992;648():328-9.
1992: Wurtman R J
Choline metabolism as a basis for the selective vulnerability of cholinergic neurons.
Trends in neurosciences 1992;15(4):117-22.
1992: Kaakkola S; Tuomainen P; Wurtman R J; Männistö P T
Effects of systemic carbidopa on dopamine synthesis in rat hypothalamus and striatum.
Journal of neural transmission. Parkinson's disease and dementia section 1992;4(2):143-54.
1992: Wurtman R J
Effects of foods on the brain. Possible implications for understanding and treating Tourette syndrome.
Advances in neurology 1992;58():293-301.
1991: Slack B E; Breu J; Wurtman R J
Production of diacylglycerol by exogenous phospholipase C stimulates CTP:phosphocholine cytidylyltransferase activity and phosphatidylcholine synthesis in human neuroblastoma cells.
The Journal of biological chemistry 1991;266(36):24503-8.
1991: Deng M H; Lopez G-Coviella I; Lynch H J; Wurtman R J
Melatonin and its precursors in Y79 human retinoblastoma cells: effect of sodium butyrate.
Brain research 1991;561(2):274-8.
1991: Berry E M; Growdon J H; Wurtman J J; Caballero B; Wurtman R J
A balanced carbohydrate: protein diet in the management of Parkinson's disease.
Neurology 1991;41(8):1295-7.
1991: Caballero B; Gleason R E; Wurtman R J
Plasma amino acid concentrations in healthy elderly men and women.
The American journal of clinical nutrition 1991;53(5):1249-52.
1991: Sandmann J; Peralta E G; Wurtman R J
Coupling of transfected muscarinic acetylcholine receptor subtypes to phospholipase D.
The Journal of biological chemistry 1991;266(10):6031-4.
1991: Sandmann J; Wurtman R J
Stimulation of phospholipase D activity in human neuroblastoma (LA-N-2) cells by activation of muscarinic acetylcholine receptors or by phorbol esters: relationship to phosphoinositide turnover.
Journal of neurochemistry 1991;56(4):1312-9.
1991: Buyukuysal R L; Holmes T C; Wurtman R J
Interactions of 3,4-diaminopyridine and choline in stimulating acetylcholine release and protecting membrane phospholipids.
Brain research 1991;541(1):1-6.
1991: Gardier A M; Wurtman R J
Persistent blockade of potassium-evoked serotonin release from rat frontocortical terminals after fluoxetine administration.
Brain research 1991;540(1-2):325-30.
1991: Caballero B; Wurtman R J
Differential effects of insulin resistance on leucine and glucose kinetics in obesity.
Metabolism: clinical and experimental 1991;40(1):51-8.
1991: Kim S H; Mauron J; Gleason R; Wurtman R
Selection of carbohydrate to protein ratio and correlations with weight gain and body fat in rats allowed three dietary choices.
International journal for vitamin and nutrition research. Internationale Zeitschrift für Vitamin- und Ernährungsforschung. Journal international de vitaminologie et de nutrition 1991;61(2):166-79.
1991: Spring B; Wurtman J; Gleason R; Wurtman R; Kessler K
Weight gain and withdrawal symptoms after smoking cessation: a preventive intervention using d-fenfluramine.
Health psychology : official journal of the Division of Health Psychology, American Psychological Association 1991;10(3):216-23.
1991: Farber S A; Buyukuysal R L; Wurtman R J
Why do phospholipid levels decrease with repeated stimulation? A study of choline-containing compounds in rat striatum following electrical stimulation.
Annals of the New York Academy of Sciences 1991;640():114-7.
1990: Blusztajn J K; Lopez Gonzalez-Coviella I; Logue M; Growdon J H; Wurtman R J
Levels of phospholipid catabolic intermediates, glycerophosphocholine and glycerophosphoethanolamine, are elevated in brains of Alzheimer's disease but not of Down's syndrome patients.
Brain research 1990;536(1-2):240-4.
1990: Schaechter J D; Wurtman R J
Serotonin release varies with brain tryptophan levels.
Brain research 1990;532(1-2):203-10.
1990: Sarkissian C F; Wurtman R J; Morse A N; Gleason R
Effects of fluoxetine or D-fenfluramine on serotonin release from, and levels in, rat frontal cortex.
Brain research 1990;529(1-2):294-301.
1990: Holbrook P G; Wurtman R J
Calcium-dependent incorporation of choline into phosphatidylcholine (PC) by base-exchange in rat brain membranes occurs preferentially with phospholipid substrates containing docosahexaenoic acid (22:6(n-3)).
Biochimica et biophysica acta 1990;1046(2):185-8.
1990: Brzezinski A A; Wurtman J J; Wurtman R J; Gleason R; Greenfield J; Nader T
d-Fenfluramine suppresses the increased calorie and carbohydrate intakes and improves the mood of women with premenstrual depression.
Obstetrics and gynecology 1990;76(2):296-301.
1990: Conlay L A; Maher T J; Wurtman R J
Alanine increases blood pressure during hypotension.
Pharmacology & toxicology 1990;66(5):415-6.
1990: Buyukuysal R L; Wurtman R J
4-Aminopyridine increases acetylcholine release without diminishing membrane phosphatidylcholine.
Journal of neurochemistry 1990;54(4):1302-9.
1990: Sturner W Q; Lynch H J; Deng M H; Gleason R E; Wurtman R J
Melatonin concentrations in the sudden infant death syndrome.
Forensic science international 1990;45(1-2):171-80.
1990: Wurtman R J; Blusztajn J K; Ulus I H; Coviella I L; Buyukuysal R L; Growdon J H; Slack B E
Choline metabolism in cholinergic neurons: implications for the pathogenesis of neurodegenerative diseases.
Advances in neurology 1990;51():117-25.
1990: Sandmann J; Wurtman R J
Phospholipase D and phospholipase C in human cholinergic neuroblastoma (LA-N-2) cells: modulation by muscarinic agonists and protein kinase C.
Advances in second messenger and phosphoprotein research 1990;24():176-81.
1989: Acworth I N; Ressler K; Wurtman R J
Feeding-associated alterations in striatal neurotransmitter release.
Annals of the New York Academy of Sciences 1989;575():596-8.
1989: Laferrere B; Wurtman R J
Effect of D-fenfluramine on serotonin release in brains of anaesthetized rats.
Brain research 1989;504(2):258-63.
1989: Schaechter J D; Wurtman R J
Tryptophan availability modulates serotonin release from rat hypothalamic slices.
Journal of neurochemistry 1989;53(6):1925-33.
1989: Wurtman J J; Brzezinski A; Wurtman R J; Laferrere B
Effect of nutrient intake on premenstrual depression.
American journal of obstetrics and gynecology 1989;161(5):1228-34.
1989: O'Rourke D; Wurtman J J; Wurtman R J; Chebli R; Gleason R
Treatment of seasonal depression with d-fenfluramine.
The Journal of clinical psychiatry 1989;50(9):343-7.
1989: Slack B E; Liscovitch M; Blusztajn J K; Wurtman R J
Uptake of exogenous phosphatidylserine by human neuroblastoma cells stimulates the incorporation of [methyl-14C]choline into phosphatidylcholine.
Journal of neurochemistry 1989;53(2):472-81.
1989: During M J; Acworth I N; Wurtman R J
Dopamine release in rat striatum: physiological coupling to tyrosine supply.
Journal of neurochemistry 1989;52(5):1449-54.
1989: Ulus I H; Wurtman R J; Mauron C; Blusztajn J K
Choline increases acetylcholine release and protects against the stimulation-induced decrease in phosphatide levels within membranes of rat corpus striatum.
Brain research 1989;484(1-2):217-27.
1989: Buyukuysal R L; Wurtman R J
Tetrahydroaminoacridine but not 4-aminopyridine inhibits high-affinity choline uptake in striatal and hippocampal synaptosomes.
Brain research 1989;482(2):371-5.
1989: Conlay L A; Wurtman R J; Lopez G-Coviella I; Blusztajn J K; Vacanti C A; Logue M; During M; Caballero B; Maher T J; Evoniuk G
Effects of running the Boston marathon on plasma concentrations of large neutral amino acids.
Journal of neural transmission 1989;76(1):65-71.
1989: Wurtman R J; O'Rourke D; Wurtman J J
Nutrient imbalances in depressive disorders. Possible brain mechanisms.
Annals of the New York Academy of Sciences 1989;575():75-82; discussion 82-5.
1989: Schaechter J D; Wurtman R J
Effect of chronic D-fenfluramine administration on rat hypothalamic serotonin levels and release.
Life sciences 1989;44(4):265-71.
1988: During M J; Acworth I N; Wurtman R J
Phenylalanine administration influences dopamine release in the rat's corpus striatum.
Neuroscience letters 1988;93(1):91-5.
1988: Acworth I N; During M J; Wurtman R J
Tyrosine: effects on catecholamine release.
Brain research bulletin 1988;21(3):473-7.
1988: Caballero B; Finer N; Wurtman R J
Plasma amino acids and insulin levels in obesity: response to carbohydrate intake and tryptophan supplements.
Metabolism: clinical and experimental 1988;37(7):672-6.
1988: Godley B F; Wurtman R J
Release of endogenous dopamine from the superfused rabbit retina in vitro: effect of light stimulation.
Brain research 1988;452(1-2):393-5.
1988: During M J; Acworth I N; Wurtman R J
Effects of systemic L-tyrosine on dopamine release from rat corpus striatum and nucleus accumbens.
Brain research 1988;452(1-2):378-80.
1988: Conlay L A; Evoniuk G; Wurtman R J
Endogenous adenosine and hemorrhagic shock: effects of caffeine administration or caffeine withdrawal.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(12):4483-5.
1988: Brzezinski A; Lynch H J; Seibel M M; Deng M H; Nader T M; Wurtman R J
The circadian rhythm of plasma melatonin during the normal menstrual cycle and in amenorrheic women.
The Journal of clinical endocrinology and metabolism 1988;66(5):891-5.
1988: Brzezinski A; Wurtman R J
The pineal gland: its possible roles in human reproduction.
Obstetrical & gynecological survey 1988;43(4):197-207.
1988: Holbrook P G; Wurtman R J
Presence of base-exchange activity in rat brain nerve endings: dependence on soluble substrate concentrations and effect of cations.
Journal of neurochemistry 1988;50(1):156-62.
1988: Conlay L A; Maher T J; Roberts C H; Wurtman R J
Effects of hemorrhagic hypotension on tyrosine concentrations in rat spinal cord and plasma.
Neurochemistry international 1988;12(3):291-5.
1988: Wurtman R J
Neurotransmitters, control of appetite, and obesity.
Current concepts in nutrition 1988;16():27-34.
1988: Wurtman R J
Effects of their nutrient precursors on the synthesis and release of serotonin, the catecholamines, and acetylcholine: implications for behavioral disorders.
Clinical neuropharmacology 1988;11 Suppl 1():S187-93.
1988: Wurtman R J; Wurtman J J
Do carbohydrates affect food intake via neurotransmitter activity?
Appetite 1988;11 Suppl 1():42-7.
1988: Kim S H; Wurtman R J
Selective effects of CGS 10686B, dl-fenfluramine or fluoxetine on nutrient selection.
Physiology & behavior 1988;42(4):319-22.
1987: Wurtman R J
Nutrients affecting brain composition and behavior.
Integrative psychiatry : IP 1987;5(4):226-38; discussion 238-57.
1987: Lieberman H R; Wurtman R J; Emde G G; Coviella I L
The effects of caffeine and aspirin on mood and performance.
Journal of clinical psychopharmacology 1987;7(5):315-20.
1987: Irie K; Wurtman R J
Release of norepinephrine from rat hypothalamic slices: effects of desipramine and tyrosine.
Brain research 1987;423(1-2):391-4.
1987: Milner J D; Reinstein D K; Wurtman R J
Dopamine synthesis in rat striatum: mobilization of tyrosine from non-dopaminergic cells.
Experientia 1987;43(10):1109-10.
1987: Lakher M; Wurtman R J
In vivo synthesis of phosphatidylcholine in rat brain via the phospholipid methylation pathway.
Brain research 1987;419(1-2):131-40.
1987: Evoniuk G; Jacobson K A; Shamim M T; Daly J W; Wurtman R J
A1- and A2-selective adenosine antagonists: in vivo characterization of cardiovascular effects.
The Journal of pharmacology and experimental therapeutics 1987;242(3):882-7.
1987: Lakher M B; Wurtman R J
Molecular composition of the phosphatidylcholines produced by the phospholipid methylation pathway in rat brain in vivo.
The Biochemical journal 1987;244(2):325-30.
1987: Brzezinski A; Seibel M M; Lynch H J; Deng M H; Wurtman R J
Melatonin in human preovulatory follicular fluid.
The Journal of clinical endocrinology and metabolism 1987;64(4):865-7.
1987: Wurtman R J; Maher T J
Effects of oral aspartame on plasma phenylalanine in humans and experimental rodents. Short note.
Journal of neural transmission 1987;70(1-2):169-73.
1987: Blusztajn J K; Liscovitch M; Mauron C; Richardson U I; Wurtman R J
Phosphatidylcholine as a precursor of choline for acetylcholine synthesis.
Journal of neural transmission. Supplementum 1987;24():247-59.
1987: Lieberman H R; Wurtman R J; Emde G G; Roberts C; Coviella I L
The effects of low doses of caffeine on human performance and mood.
Psychopharmacology 1987;92(3):308-12.
1986: Conlay L A; Wurtman R J; Blusztajn K; Coviella I L; Maher T J; Evoniuk G E
Decreased plasma choline concentrations in marathon runners.
The New England journal of medicine 1986;315(14):892.
1986: Conlay L A; Maher T J; Godley B F; Wurtman R J
Spinal cord noradrenergic neurons are activated in hypotension.
Brain research 1986;375(1):210-3.
1986: Lieberman H R; Wurtman R J
Foods and food constituents that affect the brain and human behavior.
Food technology 1986;40(1):139-41.
1986: Blusztajn J K; Holbrook P G; Lakher M; Liscovitch M; Maire J C; Mauron C; Richardson U I; Tacconi M; Wurtman R J
"Autocannibalism" of membrane choline-phospholipids: physiology and pathology.
Psychopharmacology bulletin 1986;22(3):781-6.
1985: Lieberman H R; Corkin S; Spring B J; Wurtman R J; Growdon J H
The effects of dietary neurotransmitter precursors on human behavior.
The American journal of clinical nutrition 1985;42(2):366-70.
1985: Conlay L A; Maher T J; Wurtman R J
Tyrosine accelerates catecholamine synthesis in hemorrhaged hypotensive rats.
Brain research 1985;333(1):81-4.
1985: Wurtman J; Wurtman R; Mark S; Tsay R; Gilbert W; Growdon J
d-Fenfluramine selectively suppresses carbohydrate snacking by obese subjects.
The International journal of eating disorders 1985;4(1):89-99.
1985: Lieberman H R; Garfield G; Waldhauser F; Lynch H J; Wurtman R J
Possible behavioral consequences of light-induced changes in melatonin availability.
Annals of the New York Academy of Sciences 1985;453():242-52.
1985: Lynch H J; Deng M H; Wurtman R J
Indirect effects of light: ecological and ethological considerations.
Annals of the New York Academy of Sciences 1985;453():231-41.
1984: Lieberman H R; Waldhauser F; Garfield G; Lynch H J; Wurtman R J
Effects of melatonin on human mood and performance.
Brain research 1984;323(2):201-7.
1984: Conlay L A; Maher T J; Wurtman R J
Tyrosine's pressor effect in hypotensive rats is not mediated by tyramine.
Life sciences 1984;35(11):1207-12.
1984: Lynch H J; Deng M H; Wurtman R J
Light intensities required to suppress nocturnal melatonin secretion in albino and pigmented rats.
Life sciences 1984;35(8):841-7.
1984: Lieberman H R; Corkin S; Spring B J; Garfield G S; Growdon J H; Wurtman R J
The effects of tryptophan and tyrosine on human mood and performance.
Psychopharmacology bulletin 1984;20(3):595-8.
1983: Conlay L A; Maher T J; Moses P L; Wurtman R J
Tyrosine's vasoactive effect in the dog shock model depends on the animal's starting blood pressure.
Journal of neural transmission 1983;58(1-2):69-74.
1981: Conlay L A; Maher T J; Wurtman R J
Tyrosine increases blood pressure in hypotensive rats.
Science (New York, N.Y.) 1981;212(4494):559-60.

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