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Jean-Marie Wurtz

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Christopher Browning; Elyette Martin; Caroline Loch; Jean-Marie Wurtz; Dino Moras; Roland H Stote; Annick Dejaegere; Isabelle M L Billas
Critical role of desolvation in the binding of 20-hydroxyecdysone to the ecdysone receptor.
Mathieu Lupien; M Jeyakumar; Elise Hébert; Khalid Hilmi; David Cotnoir-White; Caroline Loch; Anick Auger; Guila Dayan; Geneviève-Anne Pinard; Jean-Marie Wurtz; Dino Moras; John Katzenellenbogen; Sylvie Mader
Raloxifene and ICI182,780 increase estrogen receptor-alpha association with a nuclear compartment via overlapping sets of hydrophobic amino acids in activation function 2 helix 12.
Paul Laissue; Silvia Copelli; Ignacio Bergada; Cesar Bergada; Gabriel Barrio; Sinan Karaboga; Jean-Marie Wurtz; Marc Fellous; Enzo Lalli; Reiner A Veitia
Partial defects in transcriptional activity of two novel DAX-1 mutations in childhood-onset adrenal hypoplasia congenita.

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All Publications

2007: Christopher Browning; Elyette Martin; Caroline Loch; Jean-Marie Wurtz; Dino Moras; Roland H Stote; Annick Dejaegere; Isabelle M L Billas
Critical role of desolvation in the binding of 20-hydroxyecdysone to the ecdysone receptor.
The Journal of biological chemistry 2007;282(45):32924-34.
2007: Mathieu Lupien; M Jeyakumar; Elise Hébert; Khalid Hilmi; David Cotnoir-White; Caroline Loch; Anick Auger; Guila Dayan; Geneviève-Anne Pinard; Jean-Marie Wurtz; Dino Moras; John Katzenellenbogen; Sylvie Mader
Raloxifene and ICI182,780 increase estrogen receptor-alpha association with a nuclear compartment via overlapping sets of hydrophobic amino acids in activation function 2 helix 12.
Molecular endocrinology (Baltimore, Md.) 2007;21(4):797-816.
2006: Paul Laissue; Silvia Copelli; Ignacio Bergada; Cesar Bergada; Gabriel Barrio; Sinan Karaboga; Jean-Marie Wurtz; Marc Fellous; Enzo Lalli; Reiner A Veitia
Partial defects in transcriptional activity of two novel DAX-1 mutations in childhood-onset adrenal hypoplasia congenita.
Clinical endocrinology 2006;65(5):681-6.
2006: A Monge; Monika Jagla; Gaëlle Lapouge; Souphatta Sasorith; M Cruchant; Jean-Marie Wurtz; Didier Jacqmin; Jean-Pierre Bergerat; Jocelyn Céraline
Unfaithfulness and promiscuity of a mutant androgen receptor in a hormone-refractory prostate cancer.
Cellular and molecular life sciences : CMLS 2006;63(4):487-97.
2005: Benjamin Bertin; Stéphanie Caby; Frédérik Oger; Souphatta Sasorith; Jean-Marie Wurtz; Raymond J Pierce
The monomeric orphan nuclear receptor Schistosoma mansoni Ftz-F1 dimerizes specifically and functionally with the schistosome RXR homologue, SmRXR1.
Biochemical and biophysical research communications 2005;327(4):1072-82.
2004: Benjamin Bertin; Souphatta Sasorith; Stéphanie Caby; Frédérik Oger; Jocelyne Cornette; Jean-Marie Wurtz; Raymond J Pierce
Unique functional properties of a member of the Fushi Tarazu-Factor 1 family from Schistosoma mansoni.
The Biochemical journal 2004;382(Pt 1):337-51.
2004: Dominique Helmlinger; Sara Hardy; Souphatta Sasorith; Fabrice A C Klein; Flavie Robert; Chantal Weber; laurent miguet; Noelle Potier; Alain Van Dorsselaer; Jean-Marie Wurtz; Jean-Louis Mandel; Làszlò Tora; Didier Devys
Ataxin-7 is a subunit of GCN5 histone acetyltransferase-containing complexes.
Human molecular genetics 2004;13(12):1257-65.
2004: Giuseppe Tocchini-Valentini; Natacha Rochel; Jean-Marie Wurtz; Dino Moras
Crystal structures of the vitamin D nuclear receptor liganded with the vitamin D side chain analogues calcipotriol and seocalcitol, receptor agonists of clinical importance. Insights into a structural basis for the switching of calcipotriol to a receptor antagonist by further side chain modification.
Journal of medicinal chemistry 2004;47(8):1956-61.
2003: Sylvia G Lehmann; Jean-Marie Wurtz; Jean-Paul Renaud; Paolo Sassone-Corsi; Enzo Lalli
Structure-function analysis reveals the molecular determinants of the impaired biological function of DAX-1 mutants in AHC patients.
Human molecular genetics 2003;12(9):1063-72.
2002: Delphine Guillebault; Souphatta Sasorith; Evelyne Derelle; Jean-Marie Wurtz; Jean-Claude Lozano; Scott Bingham; Làszlò Tora; Hervé Moreau
A new class of transcription initiation factors, intermediate between TATA box-binding proteins (TBPs) and TBP-like factors (TLFs), is present in the marine unicellular organism, the dinoflagellate Crypthecodinium cohnii.
The Journal of biological chemistry 2002;277(43):40881-6.
2002: Holger Greschik; Jean-Marie Wurtz; Sarah Sanglier; William Bourguet; Alain Van Dorsselaer; Dino Moras; Jean-Paul Renaud
Structural and functional evidence for ligand-independent transcriptional activation by the estrogen-related receptor 3.
Molecular cell 2002;9(2):303-13.
2002: Souphatta Sasorith; Isabelle M L Billas; Thomas Iwema; Dino Moras; Jean-Marie Wurtz
Structure-based analysis of the ultraspiracle protein and docking studies of putative ligands.
Journal of insect science (Online) 2002;2():25.
2001: C Stehlin; Jean-Marie Wurtz; Anke Steinmetz; E Greiner; Roland Schüle; Dino Moras; Jean-Paul Renaud
X-ray structure of the orphan nuclear receptor RORbeta ligand-binding domain in the active conformation.
The EMBO journal 2001;20(21):5822-31.
2001: Giuseppe Tocchini-Valentini; Natacha Rochel; Jean-Marie Wurtz; Andre Mitschler; Dino Moras
Crystal structures of the vitamin D receptor complexed to superagonist 20-epi ligands.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(10):5491-6.
2000: Gilles Auzou; Jérôme Fagart; Anny Souque; C Hellal-Lévy; Jean-Marie Wurtz; Dino Moras; Marie-Edith Rafestin-Oblin
A single amino acid mutation of ala-773 in the mineralocorticoid receptor confers agonist properties to 11beta-substituted spirolactones.
Molecular pharmacology 2000;58(4):684-91.
2000: C Hellal-Levy; Jérôme Fagart; Anny Souque; Jean-Marie Wurtz; Dino Moras; Marie-Edith Rafestin-Oblin
Crucial role of the H11-H12 loop in stabilizing the active conformation of the human mineralocorticoid receptor.
Molecular endocrinology (Baltimore, Md.) 2000;14(8):1210-21.
2000: C Robin-Jagerschmidt; Jean-Marie Wurtz; B Guillot; D Gofflo; B Benhamou; A Vergezac; C Ossart; D Moras; D Philibert
Residues in the ligand binding domain that confer progestin or glucocorticoid specificity and modulate the receptor transactivation capacity.
Molecular endocrinology (Baltimore, Md.) 2000;14(7):1028-37.
2000: Jean-Marie Wurtz; B Guillot; Jérôme Fagart; Dino Moras; K Tietjen; M Schindler
A new model for 20-hydroxyecdysone and dibenzoylhydrazine binding: a homology modeling and docking approach.
Protein science : a publication of the Protein Society 2000;9(6):1073-84.
2000: William Bourguet; Valerie Vivat Hannah; Jean-Marie Wurtz; Pierre Chambon; Hinrich Gronemeyer; Dino Moras
Crystal structure of a heterodimeric complex of RAR and RXR ligand-binding domains.
Molecular cell 2000;5(2):289-98.
2000: Natacha Rochel; Jean-Marie Wurtz; Andre Mitschler; Bruno Klaholz; Dino Moras
The crystal structure of the nuclear receptor for vitamin D bound to its natural ligand.
Molecular cell 2000;5(1):173-9.
1999: M Correia-Neves; C Waltzinger; Jean-Marie Wurtz; Christophe Benoist; Diane Mathis
Amino acids specifying MHC class preference in TCR V alpha 2 regions.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(10):5471-7.
1999: JC Dantonel; Jean-Marie Wurtz; Olivier Poch; Dino Moras; Làszlò Tora
The TBP-like factor: an alternative transcription factor in metazoa?
Trends in biochemical sciences 1999;24(9):335-9.
1999: M Géhin; Valerie Vivat Hannah; Jean-Marie Wurtz; Régine Losson; Pierre Chambon; Dino Moras; Hinrich Gronemeyer
Structural basis for engineering of retinoic acid receptor isotype-selective agonists and antagonists.
Chemistry & biology 1999;6(8):519-29.
1999: Anne-Claire Lavigne; Mengus Gabrielle; Yann-Gaël Gangloff; Jean-Marie Wurtz; Irwin Davidson
Human TAF(II)55 interacts with the vitamin D(3) and thyroid hormone receptors and with derivatives of the retinoid X receptor that have altered transactivation properties.
Molecular and cellular biology 1999;19(8):5486-94.
1999: Holger Greschik; Jean-Marie Wurtz; Philip Hublitz; F Köhler; Dino Moras; Roland Schüle
Characterization of the DNA-binding and dimerization properties of the nuclear orphan receptor germ cell nuclear factor.
Molecular and cellular biology 1999;19(1):690-703.
1998: Jérôme Fagart; Jean-Marie Wurtz; Anny Souque; C Hellal-Levy; Dino Moras; Marie-Edith Rafestin-Oblin
Antagonism in the human mineralocorticoid receptor.
The EMBO journal 1998;17(12):3317-25.
1998: Timo Ylikomi; Jean-Marie Wurtz; Heimo Syvälä; S Passinen; A Pekki; M Haverinen; Merja Bläuer; Pentti Tuohimaa; Hinrich Gronemeyer
Reappraisal of the role of heat shock proteins as regulators of steroid receptor activity.
Critical reviews in biochemistry and molecular biology 1998;33(6):437-66.
1997: Enzo Lalli; Barbara Bardoni; E Zazopoulos; Jean-Marie Wurtz; T M Strom; Dino Moras; Paolo Sassone-Corsi
A transcriptional silencing domain in DAX-1 whose mutation causes adrenal hypoplasia congenita.
Molecular endocrinology (Baltimore, Md.) 1997;11(13):1950-60.
1997: Valerie Vivat Hannah; C Zechel; Jean-Marie Wurtz; William Bourguet; Hiroyuki Kagechika; H Umemiya; Koichi Shudo; Dino Moras; Hinrich Gronemeyer; Pierre Chambon
A mutation mimicking ligand-induced conformational change yields a constitutive RXR that senses allosteric effects in heterodimers.
The EMBO journal 1997;16(18):5697-709.
1997: F Jeanmougin; Jean-Marie Wurtz; B Le Douarin; P Chambon; Régine Losson
The bromodomain revisited.
Trends in biochemical sciences 1997;22(5):151-3.
1997: Valerie Vivat Hannah; D Gofflo; T Garcia; Jean-Marie Wurtz; William Bourguet; D Philibert; Hinrich Gronemeyer
Sequences in the ligand-binding domains of the human androgen and progesterone receptors which determine their distinct ligand identities.
Journal of molecular endocrinology 1997;18(2):147-60.
1997: G Andersen; Didier Busso; Arnaud Poterszman; J R Hwang; Jean-Marie Wurtz; Raymond Ripp; Jean-Claude Thierry; Jean-Marc Egly; Dino Moras
The structure of cyclin H: common mode of kinase activation and specific features.
The EMBO journal 1997;16(5):958-67.
1996: Sauveur-Michel Maira; Jean-Marie Wurtz; Bohdan Wasylyk
Net (ERP/SAP2) one of the Ras-inducible TCFs, has a novel inhibitory domain with resemblance to the helix-loop-helix motif.
The EMBO journal 1996;15(21):5849-65.
1996: Jean-Marie Wurtz; William Bourguet; Jean-Paul Renaud; Valerie Vivat Hannah; Pierre Chambon; Dino Moras; Hinrich Gronemeyer
A canonical structure for the ligand-binding domain of nuclear receptors.
Nature structural biology 1996;3(2):206.
1996: Jean-Marie Wurtz; William Bourguet; Jean-Paul Renaud; Valerie Vivat Hannah; Pierre Chambon; Dino Moras; Hinrich Gronemeyer
A canonical structure for the ligand-binding domain of nuclear receptors.
Nature structural biology 1996;3(1):87-94.