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David Wyper

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TOP 3
Sean J Colloby; Michael J Firbank; Sanjeet Pakrasi; Elaine K Perry; Sally Pimlott; David Wyper; Ian G McKeith; E David Williams; John T O'Brien
Alterations in nicotinic α4β2 receptor binding in vascular dementia using ¹²³I-5IA-85380 SPECT: comparison with regional cerebral blood flow.
Emma Terrière; Mary F Dempsey; Lucie L Herrmann; Kevin M Tierney; Jane A Lonie; Ronan Edward O'Carroll; Sally Pimlott; David Wyper; Karl Herholz; Klaus P. Ebmeier
5-(123)I-A-85380 binding to the α4β2-nicotinic receptor in mild cognitive impairment.
Jonathan Cavanagh; Carolyn Paterson; John McLean; Sally Pimlott; Moira McDonald; James Patterson; David Wyper; Iain McInnes
Tumour necrosis factor blockade mediates altered serotonin transporter availability in rheumatoid arthritis: a clinical, proof-of-concept study.

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All Publications

2011: Sean J Colloby; Michael J Firbank; Sanjeet Pakrasi; Elaine K Perry; Sally Pimlott; David Wyper; Ian G McKeith; E David Williams; John T O'Brien
Alterations in nicotinic α4β2 receptor binding in vascular dementia using ¹²³I-5IA-85380 SPECT: comparison with regional cerebral blood flow.
Neurobiology of aging 2011;32(2):293-301.
2010: Emma Terrière; Mary F Dempsey; Lucie L Herrmann; Kevin M Tierney; Jane A Lonie; Ronan Edward O'Carroll; Sally Pimlott; David Wyper; Karl Herholz; Klaus P. Ebmeier
5-(123)I-A-85380 binding to the α4β2-nicotinic receptor in mild cognitive impairment.
Neurobiology of aging 2010;31(11):1885-93.
2010: Jonathan Cavanagh; Carolyn Paterson; John McLean; Sally Pimlott; Moira McDonald; James Patterson; David Wyper; Iain McInnes
Tumour necrosis factor blockade mediates altered serotonin transporter availability in rheumatoid arthritis: a clinical, proof-of-concept study.
Annals of the rheumatic diseases 2010;69(6):1251-2.
2010: Jonathan Cavanagh; James Patterson; Sally Pimlott; David Wyper; Deborah Dewar
SSRI antidepressants do not confound single photon emission computed tomography (SPECT) imaging studies using the alpha4beta2 nicotinic acetylcholine receptor [123I]5-I-A85380 ligand: in vivo and in vitro evidence.
Synapse (New York, N.Y.) 2010;64(2):111-6.
2010: Sean J Colloby; Elaine K Perry; Sanjeet Pakrasi; Sally L Pimlott; David Wyper; Ian G McKeith; E David Williams; John T O'Brien
Nicotinic 123I-5IA-85380 single photon emission computed tomography as a predictor of cognitive progression in Alzheimer's disease and dementia with Lewy bodies.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2010;18(1):86-90.
2009: John McLean; David Brennan; David Wyper; Barrie Condon; Donald Hadley; Jonathan Cavanagh
Localisation of regions of intense pleasure response evoked by soccer goals.
Psychiatry research 2009;171(1):33-43.
2008: John T O'Brien; Sean J Colloby; Sanjeet Pakrasi; Elaine K Perry; Sally Pimlott; David Wyper; Ian G McKeith; E David Williams
Nicotinic alpha4beta2 receptor binding in dementia with Lewy bodies using 123I-5IA-85380 SPECT demonstrates a link between occipital changes and visual hallucinations.
NeuroImage 2008;40(3):1056-63.
2008: Emma Terrière; Mike Sharman; Claire Donaghey; Lucie Herrmann; Jane Lonie; Marion Strachan; Nadine Dougall; Jonathan Best; Klaus P. Ebmeier; Sally Pimlott; Jim Patterson; David Wyper
alpha4beta2-nicotinic receptor binding with 5-IA in Alzheimer's disease: methods of scan analysis.
Neurochemical research 2008;33(4):643-51.
2007: Sanjeet Pakrasi; Sean J Colloby; Michael J Firbank; Elaine K Perry; David Wyper; Jonathan Owens; Ian G McKeith; E David Williams; John T O'Brien
Muscarinic acetylcholine receptor status in Alzheimer's disease assessed using (R, R) 123I-QNB SPECT.
Journal of neurology 2007;254(7):907-13.
2007: John T O'Brien; Sean J Colloby; Sanjeet Pakrasi; Elaine K Perry; Sally Pimlott; David Wyper; Ian G McKeith; E David Williams
Alpha4beta2 nicotinic receptor status in Alzheimer's disease using 123I-5IA-85380 single-photon-emission computed tomography.
Journal of neurology, neurosurgery, and psychiatry 2007;78(4):356-62.
2006: Sean J Colloby; Sanjeet Pakrasi; Michael J Firbank; Elaine K Perry; Margaret A Piggott; Jonathan Owens; David Wyper; Ian G McKeith; David J Burn; E David Williams; John T O'Brien
In vivo SPECT imaging of muscarinic acetylcholine receptors using (R,R) 123I-QNB in dementia with Lewy bodies and Parkinson's disease dementia.
NeuroImage 2006;33(2):423-9.
2006: Mary F Dempsey; David Wyper; Jonathan Owens; Sally Pimlott; Vakis Papanastassiou; Jim Patterson; Donald M Hadley; Alice Nicol; Roy Rampling; S Moira Brown
Assessment of 123I-FIAU imaging of herpes simplex viral gene expression in the treatment of glioma.
Nuclear medicine communications 2006;27(8):611-7.
2006: Jonathan Cavanagh; Jim Patterson; Sally Pimlott; Deborah Dewar; Jos L H Eersels; Mary F Dempsey; David Wyper
Serotonin transporter residual availability during long-term antidepressant therapy does not differentiate responder and nonresponder unipolar patients.
Biological psychiatry 2006;59(4):301-8.
2006: Sally Pimlott; Margaret A Piggott; Clive G Ballard; Ian G McKeith; Robert H Perry; Simon Kometa; Jonathan Owens; David Wyper; Elaine K Perry
Thalamic nicotinic receptors implicated in disturbed consciousness in dementia with Lewy bodies.
Neurobiology of disease 2006;21(1):50-6.
2005: David Wyper
Editorial: symposium on nuclear imaging in dementia and depression.
Nuclear medicine communications 2005;26(3):181-2.
2004: Agnes Allen; Anna Barnes; Rajkumar S Singh; James Patterson; Donald M Hadley; David Wyper
Perfusion SPECT in cochlear implantation and promontory stimulation.
Nuclear medicine communications 2004;25(5):521-5.
2004: Sally Pimlott; Margaret A Piggott; Jonathan Owens; E Greally; Jennifer A Court; Evelyn Jaros; Robert H Perry; Elaine K Perry; David Wyper
Nicotinic acetylcholine receptor distribution in Alzheimer's disease, dementia with Lewy bodies, Parkinson's disease, and vascular dementia: in vitro binding study using 5-[(125)i]-a-85380.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2004;29(1):108-16.
2003: Kjell Erlandsson; Rodrigo A Bressan; Rachel S Mulligan; Roger Gunn; Vincent J Cunningham; Jonathan Owens; David Wyper; Peter J Ell; Lyn S Pilowsky
Kinetic modelling of [123I]CNS 1261--a potential SPET tracer for the NMDA receptor.
Nuclear medicine and biology 2003;30(4):441-54.
2003: Margaret A Piggott; Jonathan Owens; John T O'Brien; Sean J Colloby; John D Fenwick; David Wyper; Evelyn Jaros; Mary Johnson; Robert H Perry; Elaine K Perry
Muscarinic receptors in basal ganglia in dementia with Lewy bodies, Parkinson's disease and Alzheimer's disease.
Journal of chemical neuroanatomy 2003;25(3):161-73.
2003: Anna Barnes; Roderick Duncan; Jennifer A Chisholm; Kenneth Lindsay; James Patterson; David Wyper
Investigation into the mechanisms of vagus nerve stimulation for the treatment of intractable epilepsy, using 99mTc-HMPAO SPET brain images.
European journal of nuclear medicine and molecular imaging 2003;30(2):301-5.
2003: Derek Brown; Jennifer A Chisholm; Jonathan Owens; Sally Pimlott; Jim Patterson; David Wyper
Acetylcholine muscarinic receptors and response to anti-cholinesterase therapy in patients with Alzheimer's disease.
European journal of nuclear medicine and molecular imaging 2003;30(2):296-300.
2002: Margaret A Piggott; Jonathan Owens; John T O'Brien; Sean Paling; David Wyper; John Fenwick; Mary Johnson; Robert H Perry; Elaine K Perry
Comparative distribution of binding of the muscarinic receptor ligands pirenzepine, AF-DX 384, (R,R)-I-QNB and (R,S)-I-QNB to human brain.
Journal of chemical neuroanatomy 2002;24(3):211-23.
2002: Emmanuel A Stamatakis; J T Lindsay Wilson; Donald M Hadley; David Wyper
SPECT imaging in head injury interpreted with statistical parametric mapping.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2002;43(4):476-83.
2001: Emmanuel A Stamatakis; J T Lindsay Wilson; David Wyper
Spatial normalization of lesioned HMPAO-SPECT images.
NeuroImage 2001;14(4):844-52.
2001: Daniela Montaldi; Andrew R Mayes; Anna Barnes; D M Hadley; J Patterson; David Wyper
Effects of level of retrieval success on recall-related frontal and medial temporal lobe activations.
Behavioural neurology 2001;13(3-4):123-31.
2000: Hani T S Benamer; Jim Patterson; David Wyper; Donald M Hadley; Graeme Macphee; Donald G Grosset
Correlation of Parkinson's disease severity and duration with 123I-FP-CIT SPECT striatal uptake.
Movement disorders : official journal of the Movement Disorder Society 2000;15(4):692-8.
2000: Emmanuel A Stamatakis; J T Lindsay Wilson; David Wyper
Analysis of HMPAO SPECT scans in head injury using Statistical Parametric Mapping.
Behavioural neurology 2000;12(1-2):29-37.
2000: David Wyper; Daniela Montaldi
Applications of SPECT in cognitive neuroscience, neurology and psychiatry.
Behavioural neurology 2000;12(1-2):1-2.
1999: Emmanuel A Stamatakis; M F Glabus; David Wyper; Anna Barnes; J T Lindsay Wilson
Validation of statistical parametric mapping (SPM) in assessing cerebral lesions: A simulation study.
NeuroImage 1999;10(4):397-407.
1999: J Patterson; Donald M Hadley; David Wyper
Another spurious description of hyperfixation of HMPAO.
AJNR. American journal of neuroradiology 1999;20(5):941-3.
1998: Daniela Montaldi; Andrew R Mayes; Anna Barnes; H Pirie; D M Hadley; J Patterson; David Wyper
Associative encoding of pictures activates the medial temporal lobes.
Human brain mapping 1998;6(2):85-104.
1997: Anna Barnes; D Dai; Daniela Montaldi; J Patterson; David Wyper
Image quality versus statistical power.
Nuclear medicine communications 1997;18(12):1155-60.
1997: D R Brown; David Wyper; J Owens; J Patterson; R C Kelly; R Hunter; J McCulloch
123Iodo-MK-801: a spect agent for imaging the pattern and extent of glutamate (NMDA) receptor activation in Alzheimer's disease.
Journal of psychiatric research 1997;31(6):605-19.
1997: A Mitchener; David Wyper; J Patterson; Donald M Hadley; J T Lindsay Wilson; L C Scott; M Jones; Graham M Teasdale
SPECT, CT, and MRI in head injury: acute abnormalities followed up at six months.
Journal of neurology, neurosurgery, and psychiatry 1997;62(6):633-6.
1997: J Owens; David Wyper; J Patterson; D R Brown; A T Elliott; Graham M Teasdale; J McCulloch
First SPET images of glutamate (NMDA) receptor activation in vivo in cerebral ischaemia.
Nuclear medicine communications 1997;18(2):149-58.
1996: J Patterson; David Wyper; Donald M Hadley
A spurious description of hyperfixation of HMPAO.
AJNR. American journal of neuroradiology 1996;17(5):998-9; author reply 999-1000.
1996: D R Brown; R Hunter; David Wyper; Jim Patterson; R C Kelly; Daniela Montaldi; J McCullouch
Longitudinal changes in cognitive function and regional cerebral function in Alzheimer's disease: a SPECT blood flow study.
Journal of psychiatric research 1996;30(2):109-26.
1995: D E Sakas; Ross Bullock; Jim Patterson; Donald M Hadley; David Wyper; Graham M Teasdale
Focal cerebral hyperemia after focal head injury in humans: a benign phenomenon?
Journal of neurosurgery 1995;83(2):277-84.
1994: M McJury; A Blug; C Joerger; Barrie Condon; David Wyper
Short communication: acoustic noise levels during magnetic resonance imaging scanning at 1.5 T.
The British journal of radiology 1994;67(796):413-5.
1993: David Wyper; D Brown; J Patterson; J Owens; R Hunter; E Teasdale; J McCulloch
Deficits in iodine-labelled 3-quinuclidinyl benzilate binding in relation to cerebral blood flow in patients with Alzheimer's disease.
European journal of nuclear medicine 1993;20(5):379-86.
1993: David Wyper; E Teasdale; Jim Patterson; Daniela Montaldi; D Brown; R Hunter; D Graham; J McCulloch
Abnormalities in rCBF and computed tomography in patients with Alzheimer's disease and in controls.
The British journal of radiology 1993;66(781):23-7.
1993: David Wyper
Functional neuroimaging with single photon emission computed tomography (SPECT).
Cerebrovascular and brain metabolism reviews 1993;5(3):199-217.
1992: Ross Bullock; D Sakas; Jim Patterson; David Wyper; Donald M Hadley; W Maxwell; Graham M Teasdale
Early post-traumatic cerebral blood flow mapping: correlation with structural damage after focal injury.
Acta neurochirurgica. Supplementum 1992;55():14-7.
1992: Klaus P. Ebmeier; R Hunter; S M Curran; N J Dougal; C L Murray; David Wyper; J Patterson; M T Hanson; K Siegfried; Guy M Goodwin
Effects of a single dose of the acetylcholinesterase inhibitor velnacrine on recognition memory and regional cerebral blood flow in Alzheimer's disease.
Psychopharmacology 1992;108(1-2):103-9.
1991: K J Shedlack; R Hunter; David Wyper; R McLuskie; George Fink; Guy M Goodwin
The pattern of cerebral activity underlying verbal fluency shown by split-dose single photon emission tomography (SPET or SPECT) in normal volunteers.
Psychological medicine 1991;21(3):687-96.
1991: R Hunter; David Wyper; J Patterson; M T Hansen; Guy M Goodwin
Cerebral pharmacodynamics of physostigmine in Alzheimer's disease investigated using single-photon computerised tomography.
The British journal of psychiatry : the journal of mental science 1991;158():351-7.
1990: R Duncan; Jim Patterson; Donald M Hadley; David Wyper; A P McGeorge; I Bone
Tc99m HM-PAO single photon emission computed tomography in temporal lobe epilepsy.
Acta neurologica Scandinavica 1990;81(4):287-93.
1990: Daniela Montaldi; D N Brooks; John H McColl; David Wyper; Jim Patterson; E Barron; J McCulloch
Measurements of regional cerebral blood flow and cognitive performance in Alzheimer's disease.
Journal of neurology, neurosurgery, and psychiatry 1990;53(1):33-8.
1990: R Duncan; Jim Patterson; Donald M Hadley; P Macpherson; M J Brodie; I Bone; A P McGeorge; David Wyper
CT, MR and SPECT imaging in temporal lobe epilepsy.
Journal of neurology, neurosurgery, and psychiatry 1990;53(1):11-5.
1990: Ross Bullock; P Statham; Jim Patterson; David Wyper; Donald M Hadley; E Teasdale
The time course of vasogenic oedema after focal human head injury--evidence from SPECT mapping of blood brain barrier defects.
Acta neurochirurgica. Supplementum 1990;51():286-8.
1989: R Hunter; R McLuskie; David Wyper; J Patterson; J E Christie; D N Brooks; J McCulloch; George Fink; Guy M Goodwin
The pattern of function-related regional cerebral blood flow investigated by single photon emission tomography with 99mTc-HMPAO in patients with presenile Alzheimer's disease and Korsakoff's psychosis.
Psychological medicine 1989;19(4):847-55.
1989: R Grant; Barrie Condon; J Patterson; David Wyper; M D Hadley; G M Teasdale
Changes in cranial CSF volume during hypercapnia and hypocapnia.
Journal of neurology, neurosurgery, and psychiatry 1989;52(2):218-22.
1989: R Hunter; A Gordon; R McLuskie; David Wyper; J Patterson; J E Christie; George Fink; Guy M Goodwin
Gross regional cerebral hypofunction with normal CT scan in Creutzfeldt-Jakob disease.
Lancet 1989;1(8631):214.
1988: B R Condon; David Wyper; J Patterson; R Grant
Quantifying intracranial CSF volume using MRI.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1988;29(1):132-3.
1988: G M Teasdale; R Grant; Barrie Condon; Jim Patterson; A Lawrence; Donald M Hadley; David Wyper
Intracranial CSF volumes: natural variations and physiological changes measured by MRI.
Acta neurochirurgica. Supplementum 1988;42():230-5.
1987: R Duncan; J Patterson; I Bone; David Wyper
Reversible cerebellar diaschisis in focal epilepsy.
Lancet 1987;2(8559):625-6.
1987: Barrie Condon; Jim Patterson; A Jenkins; David Wyper; Donald M Hadley; R Grant; J Rowan; G Teasdale
MR relaxation times of cerebrospinal fluid.
Journal of computer assisted tomography 1987;11(2):203-7.
1987: Barrie Condon; J Patterson; David Wyper; A Jenkins; Donald M Hadley
Image non-uniformity in magnetic resonance imaging: its magnitude and methods for its correction.
The British journal of radiology 1987;60(709):83-7.
1986: David Wyper; J W Turner; Jim Patterson; Barrie Condon; K W Grossart; A Jenkins; Donald M Hadley; J O Rowan
Accuracy of stereotaxic localisation using MRI and CT.
Journal of neurology, neurosurgery, and psychiatry 1986;49(12):1445-8.
1986: B Condon; J Patterson; David Wyper; A Lawrence; D M Hadley; A Jenkins; J Rowan
Digital mapping of multi-parameter contrast functions in magnetic resonance (MR) imaging using a standard MR computer system and digital display.
Computerized radiology : official journal of the Computerized Tomography Society 1986;10(6):269-77.
1986: Barrie Condon; Jim Patterson; David Wyper; Donald M Hadley; G Teasdale; R Grant; A Jenkins; P Macpherson; J Rowan
A quantitative index of ventricular and extraventricular intracranial CSF volumes using MR imaging.
Journal of computer assisted tomography 1986;10(5):784-92.
1986: Barrie Condon; Jim Patterson; David Wyper; Donald M Hadley; R Grant; Graham M Teasdale; J Rowan
Use of magnetic resonance imaging to measure intracranial cerebrospinal fluid volume.
Lancet 1986;1(8494):1355-7.