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Guohua Xi

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Ming Dong; Richard F Keep; Guohua Xi; Ya Hua
Role of iron in brain lipocalin 2 upregulation after intracerebral hemorrhage in rats.
Shuichi Okubo; Jennifer Strahle; Ya Hua; Richard F Keep; Guohua Xi
Subarachnoid hemorrhage-induced hydrocephalus in rats.
Neeraj Chaudhary; Joseph J Gemmete; B Gregory Thompson Jr; Guohua Xi; Aditya S Pandey
Iron--potential therapeutic target in hemorrhagic stroke.

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All Publications

2013: Ming Dong; Richard F Keep; Guohua Xi; Ya Hua
Role of iron in brain lipocalin 2 upregulation after intracerebral hemorrhage in rats.
Brain research 2013;1505():86-92.
2013: Shuichi Okubo; Jennifer Strahle; Ya Hua; Richard F Keep; Guohua Xi
Subarachnoid hemorrhage-induced hydrocephalus in rats.
Stroke; a journal of cerebral circulation 2013;44(2):547-50.
2013: Neeraj Chaudhary; Joseph J Gemmete; B Gregory Thompson Jr; Guohua Xi; Aditya S Pandey
Iron--potential therapeutic target in hemorrhagic stroke.
World neurosurgery 2013;79(1):7-9.
2012: Jinhu Wang; Ya Hua; Hang Jin; Richard F Keep; Guohua Xi
Role of protease-activated receptor-1 in brain injury after experimental global cerebral ischemia.
Stroke; a journal of cerebral circulation 2012;43(9):2476-82.
2012: Richard F Keep; Ya Hua; Guohua Xi
Intracerebral haemorrhage: mechanisms of injury and therapeutic targets.
Lancet neurology 2012;11(8):720-31.
2011: Fan Zhao; Yangdong He; Ya Hua; Richard F Keep; Guohua Xi
Minocycline-induced attenuation of iron overload and brain injury after experimental intracerebral hemorrhage.
Stroke; a journal of cerebral circulation 2011;42(12):3587-93.
2011: Shukun Hu; Hang Jin; Richard F Keep; Guohua Xi; Yangdong He; Ya Hua
Thrombin-induced autophagy: a potential role in intracerebral hemorrhage.
Brain research 2011;1424():60-6.
2011: Magdy Selim; Michel Torbey; Bonnie Waldman; Guohua Xi; Sharon Yeatts; Joshua N Goldstein; Joao Gomes; Steven Greenberg; Lewis B Morgenstern; Yuko Y Palesch; Gottfried Schlaug
Safety and tolerability of deferoxamine mesylate in patients with acute intracerebral hemorrhage.
Stroke; a journal of cerebral circulation 2011;42(11):3067-74.
2011: Gang Wu; Xuhui Bao; Guohua Xi; Richard F Keep; B Gregory Thompson Jr; Ya Hua
Brain injury after intracerebral hemorrhage in spontaneously hypertensive rats.
Journal of neurosurgery 2011;114(6):1805-11.
2011: Zhi Chen; Chao Gao; Ya Hua; Richard F Keep; Karin M Muraszko; Guohua Xi
Role of iron in brain injury after intraventricular hemorrhage.
Stroke; a journal of cerebral circulation 2011;42(2):465-70.
2011: Zheng Chen; Richard F Keep; Ying Mao; Guohua Xi; Ya Hua
Effects of progesterone and testosterone on ICH-induced brain injury in rats.
Acta neurochirurgica. Supplement 2011;111():289-93.
2011: Qing Xie; Jian Guan; Richard F Keep; Gang Wu; Guohua Xi; Ya Hua
Tamoxifen treatment for intracerebral hemorrhage.
Acta neurochirurgica. Supplement 2011;111():271-5.
2011: Haitao Hu; Ya Hua; Richard F Keep; Shuijiang Song; Shiro Yamashita; Guohua Xi
Thrombin preconditioning attenuates iron-induced neuronal death.
Acta neurochirurgica. Supplement 2011;111():259-63.
2011: Shuijiang Song; Jianan Wang; Haitao Hu; Ya Hua; Guohua Xi
Thrombin preconditioning reduces iron-induced brain swelling and brain atrophy.
Acta neurochirurgica. Supplement 2011;111():219-23.
2011: Hua Hu; Richard F Keep; Masanobu Okauchi; Lin Wang; Guohua Xi; Ya Hua
Deferoxamine affects heat shock protein expression in heart after intracerebral hemorrhage in aged rats.
Acta neurochirurgica. Supplement 2011;111():197-200.
2011: Tetsuhiro Hatakeyama; Ya Hua; Richard F Keep; Masanobu Okauchi; Guohua Xi
Deferoxamine reduces cavity size in the brain after intracerebral hemorrhage in aged rats.
Acta neurochirurgica. Supplement 2011;111():185-90.
2011: Yangdong He; Ya Hua; Richard F Keep; Wenquan Liu; Michael M Wang; Guohua Xi
Hemoglobin expression in neurons and glia after intracerebral hemorrhage.
Acta neurochirurgica. Supplement 2011;111():133-7.
2011: Yuxiang Gu; Yangdong He; Hua Hu; Ya Hua; Richard F Keep; Lin Wang; Guohua Xi
Iron accumulation and DNA damage in a pig model of intracerebral hemorrhage.
Acta neurochirurgica. Supplement 2011;111():123-8.
2011: Zi Ye; Richard F Keep; Guohua Xi; Qing Xie; Ya Hua
Effects of gender on heart injury after intracerebral hemorrhage in rats.
Acta neurochirurgica. Supplement 2011;111():119-22.
2011: Ye Gong; Yuxiang Gu; Yangdong He; Richard F Keep; Guohua Xi; Ya Hua
Effects of aging on autophagy after experimental intracerebral hemorrhage.
Acta neurochirurgica. Supplement 2011;111():113-7.
2011: Fan Zhao; Richard F Keep; Wenquan Liu; Shuijiang Song; Guohua Xi; Ya Hua
Red blood cell lysis and brain tissue-type transglutaminase upregulation in a hippocampal model of intracerebral hemorrhage.
Acta neurochirurgica. Supplement 2011;111():101-5.
2011: Richard F Keep; Guohua Xi; Ya Hua; Jianming Xiang
Clot formation, vascular repair and hematoma resolution after ICH, a coordinating role for thrombin?
Acta neurochirurgica. Supplement 2011;111():71-5.
2011: Yingqi Xing; Yi Yang; Xinmei Jiang; Guohua Xi
Hemorrhagic transformation induced by acute hyperglycemia in a rat model of transient focal ischemia.
Acta neurochirurgica. Supplement 2011;111():49-54.
2011: Jin-Yul Lee; Ralf-Ingo Ernestus; Ya Hua; Richard F Keep; Guohua Xi
Deferoxamine reduces early brain injury following subarachnoid hemorrhage.
Acta neurochirurgica. Supplement 2011;112():101-6.
2011: Ryan A Frieler; He Meng; Sheng Zhong Duan; Stefan Berger; Günther Schütz; Yangdong He; Guohua Xi; Michael M Wang; richard mortensen
Myeloid-specific deletion of the mineralocorticoid receptor reduces infarct volume and alters inflammation during cerebral ischemia.
Stroke; a journal of cerebral circulation 2011;42(1):179-85.
2010: Haitao Hu; Shiro Yamashita; Ya Hua; Richard F Keep; Wenquan Liu; Guohua Xi
Thrombin-induced neuronal protection: role of the mitogen activated protein kinase/ribosomal protein S6 kinase pathway.
Brain research 2010;1361():93-101.
2010: Jin-Yul Lee; Richard F Keep; Yangdong He; Oren Sagher; Ya Hua; Guohua Xi
Hemoglobin and iron handling in brain after subarachnoid hemorrhage and the effect of deferoxamine on early brain injury.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2010;30(11):1793-803.
2010: Steven M Greenberg; James C Grotta; Guohua Xi
Intracerebral hemorrhage: introduction.
Stroke; a journal of cerebral circulation 2010;41(10 Suppl):S91.
2010: Masanobu Okauchi; Ya Hua; Richard F Keep; Lewis B Morgenstern; Timothy Schallert; Guohua Xi
Deferoxamine treatment for intracerebral hemorrhage in aged rats: therapeutic time window and optimal duration.
Stroke; a journal of cerebral circulation 2010;41(2):375-82.
2010: Takehiro Nakamura; Yasuhiro Kuroda; Naohisa Hosomi; Naohiko Okabe; Nobuyuki Kawai; Takashi Tamiya; Guohua Xi; Richard F Keep; Toshifumi Itano
Serine protease inhibitor attenuates intracerebral hemorrhage-induced brain injury and edema formation in rat.
Acta neurochirurgica. Supplement 2010;106():307-10.
2010: Y Gu; Guohua Xi; W Liu; Richard F Keep; Ya Hua
Estrogen reduces iron-mediated brain edema and neuronal death.
Acta neurochirurgica. Supplement 2010;106():159-62.
2010: Jimin Wu; Shuxu Yang; Ya Hua; W Liu; Richard F Keep; Guohua Xi
Minocycline attenuates brain edema, brain atrophy and neurological deficits after intracerebral hemorrhage.
Acta neurochirurgica. Supplement 2010;106():147-50.
2009: Yingqi Xing; Ya Hua; Richard F Keep; Guohua Xi
Effects of deferoxamine on brain injury after transient focal cerebral ischemia in rats with hyperglycemia.
Brain research 2009;1291():113-21.
2009: Jin-Yul Lee; Yangdong He; Oren Sagher; Richard F Keep; Ya Hua; Guohua Xi
Activated autophagy pathway in experimental subarachnoid hemorrhage.
Brain research 2009;1287():126-35.
2009: Ying Xu; Yuxiang Gu; Richard F Keep; Jason A Heth; Karin M Muraszko; Guohua Xi; Ya Hua
Thrombin up-regulates vascular endothelial growth factor in experimental gliomas.
Neurological research 2009;31(7):759-65.
2009: Jin-Yul Lee; Oren Sagher; Richard F Keep; Ya Hua; Guohua Xi
Comparison of experimental rat models of early brain injury after subarachnoid hemorrhage.
Neurosurgery 2009;65(2):331-43; discussion 343.
2009: Yuxiang Gu; Ya Hua; Richard F Keep; Lewis B Morgenstern; Guohua Xi
Deferoxamine reduces intracerebral hematoma-induced iron accumulation and neuronal death in piglets.
Stroke; a journal of cerebral circulation 2009;40(6):2241-3.
2009: Masanobu Okauchi; Ya Hua; Richard F Keep; Lewis B Morgenstern; Guohua Xi
Effects of deferoxamine on intracerebral hemorrhage-induced brain injury in aged rats.
Stroke; a journal of cerebral circulation 2009;40(5):1858-63.
2009: Yangdong He; Ya Hua; Wenquan Liu; Haitao Hu; Richard F Keep; Guohua Xi
Effects of cerebral ischemia on neuronal hemoglobin.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2009;29(3):596-605.
2009: Ya Hua; Richard F Keep; Yuxiang Gu; Guohua Xi
Thrombin and brain recovery after intracerebral hemorrhage.
Stroke; a journal of cerebral circulation 2009;40(3 Suppl):S88-9.
2009: Jimin Wu; Shuxu Yang; Guohua Xi; Guosheng Fu; Richard F Keep; Ya Hua
Minocycline reduces intracerebral hemorrhage-induced brain injury.
Neurological research 2009;31(2):183-8.
2009: Shu Wan; Renya Zhan; Shusen Zheng; Ya Hua; Guohua Xi
Activation of c-Jun-N-terminal kinase in a rat model of intracerebral hemorrhage: the role of iron.
Neuroscience research 2009;63(2):100-5.
2009: Masanobu Okauchi; Guohua Xi; Richard F Keep; Ya Hua
Tissue-type transglutaminase and the effects of cystamine on intracerebral hemorrhage-induced brain edema and neurological deficits.
Brain research 2009;1249():229-36.
2009: Toshihiko Kuroiwa; Guohua Xi; Ya Hua; Tavarekere N Nagaraja; Joseph D Fenstermacher; Richard F Keep
Development of a rat model of photothrombotic ischemia and infarction within the caudoputamen.
Stroke; a journal of cerebral circulation 2009;40(1):248-53.
2008: Takehiro Nakamura; Osamu Miyamoto; Tetsuhiko Toyoshima; Kazuyuki Hirooka; Nobuyuki Kawai; Fumio Shiraga; Takashi Tamiya; Guohua Xi; Richard F Keep; Toshifumi Itano
3CB2, a marker of radial glia, expression after experimental intracerebral hemorrhage: role of thrombin.
Brain research 2008;1226():156-62.
2008: Wei-Hua Tang; Zhi Chen; Zhi Liu; John Zhang; Guohua Xi; Hua Feng
The effect of ecdysterone on cerebral vasospasm following experimental subarachnoid hemorrhage in vitro and in vivo.
Neurological research 2008;30(6):571-80.
2008: Shuxu Yang; Shuijiang Song; Ya Hua; Takehiro Nakamura; Richard F Keep; Guohua Xi
Effects of thrombin on neurogenesis after intracerebral hemorrhage.
Stroke; a journal of cerebral circulation 2008;39(7):2079-84.
2008: Yangdong He; Shu Wan; Ya Hua; Richard F Keep; Guohua Xi
Autophagy after experimental intracerebral hemorrhage.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2008;28(5):897-905.
2008: Xueding Wang; David L Chamberland; Guohua Xi
Noninvasive reflection mode photoacoustic imaging through infant skull toward imaging of neonatal brains.
Journal of neuroscience methods 2008;168(2):412-21.
2008: Takehiro Nakamura; Yasuhiro Kuroda; Susumu Yamashita; Xia Zhang; Osamu Miyamoto; Takashi Tamiya; Seigo Nagao; Guohua Xi; Richard F Keep; Toshifumi Itano
Edaravone attenuates brain edema and neurologic deficits in a rat model of acute intracerebral hemorrhage.
Stroke; a journal of cerebral circulation 2008;39(2):463-9.
2008: Ya Hua; Lingling Tang; Richard F Keep; Julian T Hoff; Jason A Heth; Guohua Xi; Karin M Muraszko
Thrombin enhances glioma growth.
Acta neurochirurgica. Supplement 2008;102():363-6.
2008: Z Qin; Ya Hua; W Liu; Robert Silbergleit; Y He; Richard F Keep; Julian T Hoff; Guohua Xi
Hyperbaric oxygen preconditioning activates ribosomal protein S6 kinases and reduces brain swelling after intracerebral hemorrhage.
Acta neurochirurgica. Supplement 2008;102():317-20.
2008: T Kuroiwa; M Okauchi; Ya Hua; T Schallert; Richard F Keep; Guohua Xi
Neurological deficits and brain edema after intracerebral hemorrhage in Mongolian gerbils.
Acta neurochirurgica. Supplement 2008;105():127-30.
2008: Z Qin; Guohua Xi; Richard F Keep; Robert Silbergleit; Y He; Ya Hua
Hyperbaric oxygen for experimental intracerebral hemorrhage.
Acta neurochirurgica. Supplement 2008;105():113-7.
2008: Takehiro Nakamura; Y Kuroda; N Okabe; S Shibuya; N Kawai; T Tamiya; Guohua Xi; Richard F Keep; Toshifumi Itano; S Nagao
Radial glia marker expression following experimental intracerebral hemorrhage.
Acta neurochirurgica. Supplement 2008;105():95-7.
2008: Richard F Keep; Jianming Xiang; Steven R Ennis; Anuska A Zochowska; Ya Hua; Guohua Xi; Julian T Hoff
Blood-brain barrier function in intracerebral hemorrhage.
Acta neurochirurgica. Supplement 2008;105():73-7.
2008: Ye Gong; Guohua Xi; S Wan; Y Gu; Richard F Keep; Ya Hua
Effects of aging on complement activation and neutrophil infiltration after intracerebral hemorrhage.
Acta neurochirurgica. Supplement 2008;105():67-70.
2008: Jian Wu; Sen Yang; Guohua Xi; Shuijiang Song; G Fu; Richard F Keep; Ya Hua
Microglial activation and brain injury after intracerebral hemorrhage.
Acta neurochirurgica. Supplement 2008;105():59-65.
2008: T O'Lynnger; Y He; Howard Hu; Ya Hua; Karin M Muraszko; Guohua Xi
Concomitant intracerebral infusion of tissue plasminogen activator and thrombin leads to brain injury.
Acta neurochirurgica. Supplement 2008;105():55-8.
2008: Ye Gong; Guohua Xi; Howard Hu; Y Gu; F Huang; Richard F Keep; Ya Hua
Increase in brain thrombin activity after experimental intracerebral hemorrhage.
Acta neurochirurgica. Supplement 2008;105():47-50.
2008: S Yamashita; M Okauchi; Ya Hua; W Liu; Richard F Keep; Guohua Xi
Metallothionein and brain injury after intracerebral hemorrhage.
Acta neurochirurgica. Supplement 2008;105():37-40.
2008: Y He; Ya Hua; Shuijiang Song; W Liu; Richard F Keep; Guohua Xi
Induction of autophagy in rat hippocampus and cultured neurons by iron.
Acta neurochirurgica. Supplement 2008;105():29-32.
2008: Shuijiang Song; Ya Hua; Richard F Keep; Y He; Jie Wang; Jimin Wu; Guohua Xi
Deferoxamine reduces brain swelling in a rat model of hippocampal intracerebral hemorrhage.
Acta neurochirurgica. Supplement 2008;105():13-8.
2008: Ya Hua; Richard F Keep; Julian T Hoff; Guohua Xi
Deferoxamine therapy for intracerebral hemorrhage.
Acta neurochirurgica. Supplement 2008;105():3-6.
2007: Jason R Cannon; Ya Hua; Rudy Richardson; Guohua Xi; Richard F Keep; Timothy Schallert
The effect of thrombin on a 6-hydroxydopamine model of Parkinson's disease depends on timing.
Behavioural brain research 2007;183(2):161-8.
2007: Jason R Cannon; Guohua Xi; Richard F Keep
Recent research on changes in genomic regulation and protein expression in intracerebral haemorrhage.
International journal of stroke : official journal of the International Stroke Society 2007;2(4):265-9.
2007: Shuijiang Song; Ya Hua; Richard F Keep; Julian T Hoff; Guohua Xi
A new hippocampal model for examining intracerebral hemorrhage-related neuronal death: effects of deferoxamine on hemoglobin-induced neuronal death.
Stroke; a journal of cerebral circulation 2007;38(10):2861-3.
2007: Zhiyong Qin; Murat Karabiyikoglu; Ya Hua; Robert Silbergleit; Yangdong He; Richard F Keep; Guohua Xi
Hyperbaric oxygen-induced attenuation of hemorrhagic transformation after experimental focal transient cerebral ischemia.
Stroke; a journal of cerebral circulation 2007;38(4):1362-7.
2007: Ya Hua; Richard F Keep; Julian T Hoff; Guohua Xi
Brain injury after intracerebral hemorrhage: the role of thrombin and iron.
Stroke; a journal of cerebral circulation 2007;38(2 Suppl):759-62.
2007: Zhiyong Qin; Shuijiang Song; Guohua Xi; Robert Silbergleit; Richard F Keep; Julian T Hoff; Ya Hua
Preconditioning with hyperbaric oxygen attenuates brain edema after experimental intracerebral hemorrhage.
Neurosurgical focus 2007;22(5):E13.
2006: Shuxu Yang; Takehiro Nakamura; Ya Hua; Richard F Keep; John Younger; Yangdong He; Julian T Hoff; Guohua Xi
The role of complement C3 in intracerebral hemorrhage-induced brain injury.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2006;26(12):1490-5.
2006: Jason R Cannon; Richard F Keep; Timothy Schallert; Ya Hua; Rudy Richardson; Guohua Xi
Protease-activated receptor-1 mediates protection elicited by thrombin preconditioning in a rat 6-hydroxydopamine model of Parkinson's disease.
Brain research 2006;1116(1):177-86.
2006: Ya Hua; Jimin Wu; Richard F Keep; Takehiro Nakamura; Julian T Hoff; Guohua Xi
Tumor necrosis factor-alpha increases in the brain after intracerebral hemorrhage and thrombin stimulation.
Neurosurgery 2006;58(3):542-50; discussion 542-50.
2006: Ya Hua; Takehiro Nakamura; Richard F Keep; Jimin Wu; Timothy Schallert; Julian T Hoff; Guohua Xi
Long-term effects of experimental intracerebral hemorrhage: the role of iron.
Journal of neurosurgery 2006;104(2):305-12.
2006: Ye Gong; H Tian; Guohua Xi; Richard F Keep; Julian T Hoff; Ya Hua
Systemic zinc protoporphyrin administration reduces intracerebral hemorrhage-induced brain injury.
Acta neurochirurgica. Supplement 2006;96():232-6.
2006: Shuxu Yang; Takehiro Nakamura; Ya Hua; Richard F Keep; John Younger; Julian T Hoff; Guohua Xi
Intracerebral hemorrhage in complement C3-deficient mice.
Acta neurochirurgica. Supplement 2006;96():227-31.
2006: Jason R Cannon; Takehiro Nakamura; Richard F Keep; Rudy Richardson; Ya Hua; Guohua Xi
Dopamine changes in a rat model of intracerebral hemorrhage.
Acta neurochirurgica. Supplement 2006;96():222-6.
2006: Takehiro Nakamura; Guohua Xi; Richard F Keep; Michael M Wang; Seigo Nagao; Julian T Hoff; Ya Hua
Effects of endogenous and exogenous estrogen on intracerebral hemorrhage-induced brain damage in rats.
Acta neurochirurgica. Supplement 2006;96():218-21.
2006: Shuxu Yang; Ya Hua; Takehiro Nakamura; Richard F Keep; Guohua Xi
Up-regulation of brain ceruloplasmin in thrombin preconditioning.
Acta neurochirurgica. Supplement 2006;96():203-6.
2006: S Wan; Ya Hua; Richard F Keep; Julian T Hoff; Guohua Xi
Deferoxamine reduces CSF free iron levels following intracerebral hemorrhage.
Acta neurochirurgica. Supplement 2006;96():199-202.
2006: Takehiro Nakamura; Richard F Keep; Ya Hua; Seigo Nagao; Julian T Hoff; Guohua Xi
Iron-induced oxidative brain injury after experimental intracerebral hemorrhage.
Acta neurochirurgica. Supplement 2006;96():194-8.
2006: Jie Shao; Guohua Xi; Ya Hua; Timothy Schallert; Barbara Felt
Alterations in intracerebral hemorrhage-induced brain injury in the iron deficient rat.
Acta neurochirurgica. Supplement 2006;96():183-7.
2006: G Wu; Guohua Xi; F Huang
Spontaneous intracerebral hemorrhage in humans: hematoma enlargement, clot lysis, and brain edema.
Acta neurochirurgica. Supplement 2006;96():78-80.
2006: Guohua Xi; Richard F Keep; Julian T Hoff
Mechanisms of brain injury after intracerebral haemorrhage.
Lancet neurology 2006;5(1):53-63.
2005: Murat Karabiyikoglu; Richard F Keep; Ya Hua; Guohua Xi
Acute subdural hematoma: new model delineation and effects of coagulation inhibitors.
Neurosurgery 2005;57(3):565-72; discussion 565-72.
2005: Ya Hua; L Tang; Richard F Keep; Timothy Schallert; Matthew E Fewel; Karin M Muraszko; Julian T Hoff; Guohua Xi
The role of thrombin in gliomas.
Journal of thrombosis and haemostasis : JTH 2005;3(9):1917-23.
2005: Takehiro Nakamura; Ya Hua; Richard F Keep; Jung-Weon Park; Guohua Xi; Julian T Hoff
Estrogen therapy for experimental intracerebral hemorrhage in rats.
Journal of neurosurgery 2005;103(1):97-103.
2005: Richard F Keep; Guohua Xi; Ya Hua; Julian T Hoff
The deleterious or beneficial effects of different agents in intracerebral hemorrhage: think big, think small, or is hematoma size important?
Stroke; a journal of cerebral circulation 2005;36(7):1594-6.
2005: Ya Hua; Jimin Wu; Susana Pecina; Shuxu Yang; Timothy Schallert; Richard F Keep; Guohua Xi
Ischemic preconditioning procedure induces behavioral deficits in the absence of brain injury?
Neurological research 2005;27(3):261-7.
2005: Takehiro Nakamura; Richard F Keep; Ya Hua; Julian T Hoff; Guohua Xi
Oxidative DNA injury after experimental intracerebral hemorrhage.
Brain research 2005;1039(1-2):30-6.
2005: Jie Shao; Guohua Xi; Ya Hua; Timothy Schallert; Barbara Felt
Intracerebral hemorrhage in the iron-deficient rat.
Stroke; a journal of cerebral circulation 2005;36(3):660-4.
2005: Takehiro Nakamura; Guohua Xi; Jung-Weon Park; Ya Hua; Julian T Hoff; Richard F Keep
Holo-transferrin and thrombin can interact to cause brain damage.
Stroke; a journal of cerebral circulation 2005;36(2):348-52.
2005: Jason R Cannon; Richard F Keep; Ya Hua; Rudy Richardson; Timothy Schallert; Guohua Xi
Thrombin preconditioning provides protection in a 6-hydroxydopamine Parkinson's disease model.
Neuroscience letters 2005;373(3):189-94.
2005: Ye Gong; Guohua Xi; Richard F Keep; Julian T Hoff; Ya Hua
Aging enhances intracerebral hemorrhage-induced brain injury in rats.
Acta neurochirurgica. Supplement 2005;95():425-7.
2005: Takehiro Nakamura; Richard F Keep; Ya Hua; Jung-Weon Park; Toshifumi Itano; Seigo Nagao; Julian T Hoff; Guohua Xi
Intracerebral hemorrhage induces edema and oxidative stress and alters N-methyl-D-aspartate receptor subunits expression.
Acta neurochirurgica. Supplement 2005;95():421-4.
2005: Ya Hua; L L Tang; Matthew E Fewel; Richard F Keep; Timothy Schallert; Karin M Muraszko; Julian T Hoff; Guohua Xi
Systemic use of argatroban reduces tumor mass, attenuates neurological deficits and prolongs survival time in rat glioma models.
Acta neurochirurgica. Supplement 2005;95():403-6.
2005: Ye Gong; Guohua Xi; Richard F Keep; Julian T Hoff; Ya Hua
Complement inhibition attenuates brain edema and neurological deficits induced by thrombin.
Acta neurochirurgica. Supplement 2005;95():389-92.
2004: Ye Gong; Ya Hua; Richard F Keep; Julian T Hoff; Guohua Xi
Intracerebral hemorrhage: effects of aging on brain edema and neurological deficits.
Stroke; a journal of cerebral circulation 2004;35(11):2571-5.
2004: Takehiro Nakamura; Guohua Xi; Ya Hua; Timothy Schallert; Julian T Hoff; Richard F Keep
Intracerebral hemorrhage in mice: model characterization and application for genetically modified mice.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2004;24(5):487-94.
2004: Takehiro Nakamura; Richard F Keep; Ya Hua; Timothy Schallert; Julian T Hoff; Guohua Xi
Deferoxamine-induced attenuation of brain edema and neurological deficits in a rat model of intracerebral hemorrhage.
Journal of neurosurgery 2004;100(4):672-8.
2004: Murat Karabiyikoglu; Ya Hua; Richard F Keep; Steven R Ennis; Guohua Xi
Intracerebral hirudin injection attenuates ischemic damage and neurologic deficits without altering local cerebral blood flow.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2004;24(2):159-66.
2004: Guohua Xi; Matthew E Fewel; Ya Hua; B Gregory Thompson Jr; Julian T Hoff; Richard F Keep
Intracerebral hemorrhage: pathophysiology and therapy.
Neurocritical care 2004;1(1):5-18.
2003: Ya Hua; Richard F Keep; Julian T Hoff; Guohua Xi
Thrombin preconditioning attenuates brain edema induced by erythrocytes and iron.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2003;23(12):1448-54.
2003: Jimin Wu; Ya Hua; Richard F Keep; Takehiro Nakamura; Julian T Hoff; Guohua Xi
Iron and iron-handling proteins in the brain after intracerebral hemorrhage.
Stroke; a journal of cerebral circulation 2003;34(12):2964-9.
2003: Takehiro Nakamura; Richard F Keep; Ya Hua; Timothy Schallert; Julian T Hoff; Guohua Xi
Deferoxamine-induced attenuation of brain edema and neurological deficits in a rat model of intracerebral hemorrhage.
Neurosurgical focus 2003;15(4):ECP4.
2003: Takehiro Nakamura; Guohua Xi; Ya Hua; Julian T Hoff; Richard F Keep
Nestin expression after experimental intracerebral hemorrhage.
Brain research 2003;981(1-2):108-17.
2003: Ya Hua; Richard F Keep; Timothy Schallert; Julian T Hoff; Guohua Xi
A thrombin inhibitor reduces brain edema, glioma mass and neurological deficits in a rat glioma model.
Acta neurochirurgica. Supplement 2003;86():503-6.
2003: Tetsuya Masada; Ya Hua; Guohua Xi; Guo-Yuan Yang; Julian T Hoff; Richard F Keep; Seigo Nagao
Overexpression of interleukin-1 receptor antagonist reduces brain edema induced by intracerebral hemorrhage and thrombin.
Acta neurochirurgica. Supplement 2003;86():463-7.
2003: T Kitaoka; Ya Hua; Guohua Xi; Seigo Nagao; Julian T Hoff; Richard F Keep
Effect of delayed argatroban treatment on intracerebral hemorrhage-induced edema in the rat.
Acta neurochirurgica. Supplement 2003;86():457-61.
2003: Guohua Xi; Jimin Wu; Y Jiang; Ya Hua; Richard F Keep; Julian T Hoff
Thrombin preconditioning upregulates transferrin and transferrin receptor and reduces brain edema induced by lysed red blood cells.
Acta neurochirurgica. Supplement 2003;86():449-52.
2003: Ya Hua; Jimin Wu; Richard F Keep; Julian T Hoff; Guohua Xi
Thrombin exacerbates brain edema in focal cerebral ischemia.
Acta neurochirurgica. Supplement 2003;86():163-6.
2003: Julian T Hoff; Guohua Xi
Brain edema from intracerebral hemorrhage.
Acta neurochirurgica. Supplement 2003;86():11-5.
2003: Guohua Xi; Georg Reiser; Richard F Keep
The role of thrombin and thrombin receptors in ischemic, hemorrhagic and traumatic brain injury: deleterious or protective?
Journal of neurochemistry 2003;84(1):3-9.
2002: Takuji Kitaoka; Ya Hua; Guohua Xi; Julian T Hoff; Richard F Keep
Delayed argatroban treatment reduces edema in a rat model of intracerebral hemorrhage.
Stroke; a journal of cerebral circulation 2002;33(12):3012-8.
2002: Jimin Wu; Ya Hua; Richard F Keep; Timothy Schallert; Julian T Hoff; Guohua Xi
Oxidative brain injury from extravasated erythrocytes after intracerebral hemorrhage.
Brain research 2002;953(1-2):45-52.
2002: Ya Hua; Timothy Schallert; Richard F Keep; Jimin Wu; Julian T Hoff; Guohua Xi
Behavioral tests after intracerebral hemorrhage in the rat.
Stroke; a journal of cerebral circulation 2002;33(10):2478-84.
2002: Guohua Xi; Richard F Keep; Julian T Hoff
Pathophysiology of brain edema formation.
Neurosurgery clinics of North America 2002;13(3):371-83.
2002: Yajun Jiang; Jimin Wu; Richard F Keep; Ya Hua; Julian T Hoff; Guohua Xi
Hypoxia-inducible factor-1alpha accumulation in the brain after experimental intracerebral hemorrhage.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2002;22(6):689-96.
2002: Yajun Jiang; Jimin Wu; Ya Hua; Richard F Keep; Jianming Xiang; Julian T Hoff; Guohua Xi
Thrombin-receptor activation and thrombin-induced brain tolerance.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2002;22(4):404-10.
2002: Feng-Ping Huang; Guohua Xi; Richard F Keep; Ya Hua; Andrei Nemoianu; Julian T Hoff
Brain edema after experimental intracerebral hemorrhage: role of hemoglobin degradation products.
Journal of neurosurgery 2002;96(2):287-93.
2002: Tetsuya Masada; Ya Hua; Guohua Xi; Steven R Ennis; Richard F Keep
Effect of ischemic preconditioning on edema formation and cerebrovascular injury following focal cerebral ischemia.
Acta neurochirurgica. Supplement 2002;81():265-8.
2002: Guohua Xi; Ya Hua; Richard F Keep; John Younger; Julian T Hoff
Brain edema after intracerebral hemorrhage: the effects of systemic complement depletion.
Acta neurochirurgica. Supplement 2002;81():253-6.
2002: R R Bhasin; Guohua Xi; Ya Hua; Richard F Keep; Julian T Hoff
Experimental intracerebral hemorrhage: effect of lysed erythrocytes on brain edema and blood-brain barrier permeability.
Acta neurochirurgica. Supplement 2002;81():249-51.
2002: Ya Hua; Guohua Xi; Richard F Keep; Jimin Wu; Yajun Jiang; Julian T Hoff
Plasminogen activator inhibitor-1 induction after experimental intracerebral hemorrhage.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2002;22(1):55-61.
2001: Guohua Xi; Ya Hua; R R Bhasin; Steven R Ennis; Richard F Keep; Julian T Hoff
Mechanisms of edema formation after intracerebral hemorrhage: effects of extravasated red blood cells on blood flow and blood-brain barrier integrity.
Stroke; a journal of cerebral circulation 2001;32(12):2932-8.
2001: Tetsuya Masada; Ya Hua; Guohua Xi; Guo-Yuan Yang; Julian T Hoff; Richard F Keep
Attenuation of intracerebral hemorrhage and thrombin-induced brain edema by overexpression of interleukin-1 receptor antagonist.
Journal of neurosurgery 2001;95(4):680-6.
2001: Guohua Xi; Ya Hua; Richard F Keep; H K Duong; Julian T Hoff
Activation of p44/42 mitogen activated protein kinases in thrombin-induced brain tolerance.
Brain research 2001;895(1-2):153-9.
2001: Tetsuya Masada; Ya Hua; Guohua Xi; Steven R Ennis; Richard F Keep
Attenuation of ischemic brain edema and cerebrovascular injury after ischemic preconditioning in the rat.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2001;21(1):22-33.
2001: Guohua Xi; Ya Hua; Richard F Keep; John Younger; Julian T Hoff
Systemic complement depletion diminishes perihematomal brain edema in rats.
Stroke; a journal of cerebral circulation 2001;32(1):162-7.
2000: Tetsuya Masada; Guohua Xi; Ya Hua; Richard F Keep
The effects of thrombin preconditioning on focal cerebral ischemia in rats.
Brain research 2000;867(1-2):173-9.
2000: Ya Hua; Guohua Xi; Richard F Keep; Julian T Hoff
Complement activation in the brain after experimental intracerebral hemorrhage.
Journal of neurosurgery 2000;92(6):1016-22.
2000: Guohua Xi; Richard F Keep; Ya Hua; Julian T Hoff
Thrombin preconditioning, heat shock proteins and thrombin-induced brain edema.
Acta neurochirurgica. Supplement 2000;76():511-5.
2000: Guohua Xi; Ya Hua; Richard F Keep; Julian T Hoff
Induction of colligin may attenuate brain edema following intracerebral hemorrhage.
Acta neurochirurgica. Supplement 2000;76():501-5.
2000: Gabrielle M De Courten-Myers; Guohua Xi; J H Hwang; R Scott Dunn; A S Mills; Scott K Holland; Kenneth R Wagner; RE Myers
Hypoglycemic brain injury: potentiation from respiratory depression and injury aggravation from hyperglycemic treatment overshoots.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2000;20(1):82-92.
1999: Guohua Xi; Richard F Keep; Ya Hua; Jianming Xiang; Julian T Hoff
Attenuation of thrombin-induced brain edema by cerebral thrombin preconditioning.
Stroke; a journal of cerebral circulation 1999;30(6):1247-55.
1999: Kenneth R Wagner; Guohua Xi; Ya Hua; Mario Zuccarello; Gabrielle M De Courten-Myers; Joseph P Broderick; Thomas G Brott
Ultra-early clot aspiration after lysis with tissue plasminogen activator in a porcine model of intracerebral hemorrhage: edema reduction and blood-brain barrier protection.
Journal of neurosurgery 1999;90(3):491-8.
1998: Guohua Xi; Kenneth R Wagner; Richard F Keep; Ya Hua; Gabrielle M De Courten-Myers; Joseph P Broderick; Thomas G Brott; J T Hoff
Role of blood clot formation on early edema development after experimental intracerebral hemorrhage.
Stroke; a journal of cerebral circulation 1998;29(12):2580-6.
1998: Guohua Xi; Richard F Keep; Julian T Hoff
Erythrocytes and delayed brain edema formation following intracerebral hemorrhage in rats.
Journal of neurosurgery 1998;89(6):991-6.
1998: Kenneth R Wagner; Guohua Xi; Ya Hua; M Kleinholz; Gabrielle M De Courten-Myers; RE Myers
Early metabolic alterations in edematous perihematomal brain regions following experimental intracerebral hemorrhage.
Journal of neurosurgery 1998;88(6):1058-65.
1996: T Rabinowicz; Gabrielle M De Courten-Myers; J M Petetot; Guohua Xi; E de los Reyes
Human cortex development: estimates of neuronal numbers indicate major loss late during gestation.
Journal of neuropathology and experimental neurology 1996;55(3):320-8.
1996: Kenneth R Wagner; Guohua Xi; Ya Hua; M Kleinholz; Gabrielle M De Courten-Myers; R E Myers; J P Broderick; T G Brott
Lobar intracerebral hemorrhage model in pigs: rapid edema development in perihematomal white matter.
Stroke; a journal of cerebral circulation 1996;27(3):490-7.
1994: Gabrielle M De Courten-Myers; M Kleinholz; Kenneth R Wagner; Guohua Xi; R E Myers
Efficacious experimental stroke treatment with high-dose methylprednisolone.
Stroke; a journal of cerebral circulation 1994;25(2):487-92; discussion 493.
1993: Guohua Xi
[Measurement of human erythrocyte membrane potential with microelectrode].
Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae 1993;15(3):206-11.
1991: Guohua Xi
[Successive detection of cortex oxygen partial pressure with oxygen microelectrodes in cats].
Zhonghua yi xue za zhi 1991;71(9):508-10, 36.
1991: L H Ding; Guohua Xi; D Y Ding; B Yu; J F Zhou; M Wu
Effects of naloxone on tissue oxygen supply and somatosensory evoked potentials in cat brain during focal cerebral ischemia.
Zhongguo yao li xue bao = Acta pharmacologica Sinica 1991;12(4):312-5.