Preview
Sign-in for full Details 
Sign-in free and Explore the Exciting World of BiomedExperts:
- Over 1.500.000 Profiles
- More than 1.800 Organizations worldwide
- State of the Art Network Visualizations
- Manage your own Profile
- Locate Experts in your Country/Region
- Locate Experts in your 1. and 2. Level Network
- Connect to Experts Worldwide
NetworkView
Wen Xie
This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers
together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles
free of charge to researchers worldwide.
Research Profile (preview)
Chemicals & Drugs
Living Beings
Anatomy
Physiology
Sign-in to see full Profile
Network (preview)
16
Evans, Ronald
11
Mu, Ying
11
Ren, Songrong
10
Li, Song
10
Herbert, Gong
9
Uppal, Hirdesh
8
Toma, David
8
Saini, Simrat
8
Zhou, Jie
7
Zhai, Yonggong
5
Li, Jiang
5
Gao, Xiang
4
He, Fengtian
4
Day, Billy
4
Downes, Michael
Sign-in to see all Coauthors
Publications
Sign-in to see all Publications
Sign in free and see...
Visualized networks:
See your personal network in
sophisticated graphical views
GeoTargeted Searches:
Locate experts around the world
and connect with global collaborators
Research Profiles:
See the visualized research activity
of experts around the globe
Sign-in to see more
Geonetwork of Wen Xie (preview)
Cities where this author has publications
Cities where co-authors of this author have publications
Sign-in to see more
All Publications
-
2009: Li Jiang; Wilson Annette; Gao Xiang; Kuruba Ramalinga; Liu Youhua; Poloyac Samuel; Pitt Bruce; Xie Wen; Li Song
Coordinated regulation of dimethylarginine dimethylaminohydrolase-1 and cationic amino acid transporter-1 by farnesoid X receptor in mouse liver and kidney and its implication in the control of blood levels of asymmetric dimethylarginine.
The Journal of pharmacology and experimental therapeutics 2009;331(1):234-43.
-
2009: Liu Ming-Jie; Takahashi Yuki; Wada Taira; He Jinhan; Gao Jie; Tian Yanan; Li Song; Xie Wen
The aldo-keto reductase Akr1b7 gene is a common transcriptional target of xenobiotic receptors pregnane X receptor and constitutive androstane receptor.
Molecular pharmacology 2009;76(3):604-11.
-
2009: Wada Taira; Gao Jie; Xie Wen
PXR and CAR in energy metabolism.
Trends in endocrinology and metabolism: TEM 2009;20(6):273-9.
-
2009: Tortorici Michael A; Mu Ying; Kochanek Patrick M; Xie Wen; Poloyac Samuel M
Moderate hypothermia prevents cardiac arrest-mediated suppression of drug metabolism and induction of interleukin-6 in rats.
Critical care medicine 2009;37(1):263-9.
-
2009: Lu Yi; Chen Qiuyan; Corey Eva; Xie Wen; Fan Jie; Mizokami Atsushi; Zhang Jian
Activation of MCP-1/CCR2 axis promotes prostate cancer growth in bone.
Clinical & experimental metastasis 2009;26(2):161-9.
-
2008: Zhang Bin; Xie Wen; Krasowski Matthew D
PXR: a xenobiotic receptor of diverse function implicated in pharmacogenetics.
Pharmacogenomics 2008;9(11):1695-709.
-
2008: Wada Taira; Kang Hong Soon; Jetten Anton M; Xie Wen
The emerging role of nuclear receptor RORalpha and its crosstalk with LXR in xeno- and endobiotic gene regulation.
Experimental biology and medicine (Maywood, N.J.) 2008;233(10):1191-201.
-
2008: Gong Haibiao; Jarzynka Michael J; Cole Timothy J; Lee Jung Hoon; Wada Taira; Zhang Bin; Gao Jie; Song Wen-Chao; DeFranco Donald B; Cheng Shi-Yuan; Xie Wen
Glucocorticoids antagonize estrogens by glucocorticoid receptor-mediated activation of estrogen sulfotransferase.
Cancer research 2008;68(18):7386-93.
-
2008: He Fengtian; Zhang Qiuhong; Kuruba Ramalinga; Gao Xiang; Li Jiang; Li Yong; Gong Wei; Jiang Yu; Xie Wen; Li Song
Upregulation of decorin by FXR in vascular smooth muscle cells.
Biochemical and biophysical research communications 2008;372(4):746-51.
-
2008: Lee Jung Hoon; Gong Haibiao; Khadem Shaheen; Lu Yi; Gao Xiang; Li Song; Zhang Jian; Xie Wen
Androgen deprivation by activating the liver X receptor.
Endocrinology 2008;149(8):3778-88.
-
2008: Uppal Hirdesh; Zhai Yonggong; Gangopadhyay Archana; Khadem Shaheen; Ren Songrong; Moser James A; Xie Wen
Activation of liver X receptor sensitizes mice to gallbladder cholesterol crystallization.
Hepatology (Baltimore, Md.) 2008;47(4):1331-42.
-
2008: Zhou Jie; Liu Mingjie; Zhai Yonggong; Xie Wen
The antiapoptotic role of pregnane X receptor in human colon cancer cells.
Molecular endocrinology (Baltimore, Md.) 2008;22(4):868-80.
-
2008: Wada Taira; Kang Hong Soon; Angers Martin; Gong Haibiao; Bhatia Shikha; Khadem Shaheen; Ren Songrong; Ellis Ewa; Strom Stephen C; Jetten Anton M; Xie Wen
Identification of oxysterol 7alpha-hydroxylase (Cyp7b1) as a novel retinoid-related orphan receptor alpha (RORalpha) (NR1F1) target gene and a functional cross-talk between RORalpha and liver X receptor (NR1H3).
Molecular pharmacology 2008;73(3):891-9.
-
2008: Zhou Jie; Febbraio Maria; Wada Taira; Zhai Yonggong; Kuruba Ramalinga; He Jinhan; Lee Jung Hoon; Khadem Shaheen; Ren Songrong; Li Song; Silverstein Roy L; Xie Wen
Hepatic fatty acid transporter Cd36 is a common target of LXR, PXR, and PPARgamma in promoting steatosis.
Gastroenterology 2008;134(2):556-67.
-
2008: Zhang Qiuhong; He Fengtian; Kuruba Ramalinga; Gao Xiang; Wilson Annette; Li Jiang; Billiar Timothy R; Pitt Bruce R; Xie Wen; Li Song
FXR-mediated regulation of angiotensin type 2 receptor expression in vascular smooth muscle cells.
Cardiovascular research 2008;77(3):560-9.
-
2008: Li Jiang; Wilson Annette; Kuruba Ramalinga; Zhang Qiuhong; Gao Xiang; He Fengtian; Zhang Li-Ming; Pitt Bruce R; Xie Wen; Li Song
FXR-mediated regulation of eNOS expression in vascular endothelial cells.
Cardiovascular research 2008;77(1):169-77.
-
2007: Gong Haibiao; Guo Ping; Zhai Yonggong; Zhou Jie; Uppal Hirdesh; Jarzynka Michael J; Song Wen-Chao; Cheng Shi-Yuan; Xie Wen
Estrogen deprivation and inhibition of breast cancer growth in vivo through activation of the orphan nuclear receptor liver X receptor.
Molecular endocrinology (Baltimore, Md.) 2007;21(8):1781-90.
-
2007: Sáenz-Robles M T; Toma D; Cantalupo P; Zhou J; Gong H; Edwards C; Pipas J M; Xie W
Repression of intestinal drug metabolizing enzymes by the SV40 large T antigen.
Oncogene 2007;26(35):5124-31.
-
2007: Alaynick William A; Kondo Richard P; Xie Wen; He Weimin; Dufour Catherine R; Downes Michael; Jonker Johan W; Giles Wayne; Naviaux Robert K; Giguère Vincent; Evans Ronald M
ERRgamma directs and maintains the transition to oxidative metabolism in the postnatal heart.
Cell metabolism 2007;6(1):13-24.
-
2007: Wipf Peter; Gong Haibiao; Janjic Jelena M; Li Song; Day Billy W; Xie Wen
New opportunities for pregnane X receptor (PXR) targeting in drug development. lessons from Enantio- and species-specific PXR ligands identified from a discovery library of amino acid analogues.
Mini reviews in medicinal chemistry 2007;7(6):617-25.
-
2007: Uppal Hirdesh; Saini Simrat P S; Moschetta Antonio; Mu Ying; Zhou Jie; Gong Haibiao; Zhai Yonggong; Ren Songrong; Michalopoulos George K; Mangelsdorf David J; Xie Wen
Activation of LXRs prevents bile acid toxicity and cholestasis in female mice.
Hepatology (Baltimore, Md.) 2007;45(2):422-32.
-
2007: Zhai Yonggong; Pai Harish V; Zhou Jie; Amico Janet A; Vollmer Regis R; Xie Wen
Activation of pregnane X receptor disrupts glucocorticoid and mineralocorticoid homeostasis.
Molecular endocrinology (Baltimore, Md.) 2007;21(1):138-47.
-
2006: Xie Wen; Tian Yanan
Xenobiotic receptor meets NF-kappaB, a collision in the small bowel.
Cell metabolism 2006;4(3):177-8.
-
2006: Zhou Jie; Zhai Yonggong; Mu Ying; Gong Haibiao; Uppal Hirdesh; Toma David; Ren Songrong; Evans Ronald M; Xie Wen
A novel pregnane X receptor-mediated and sterol regulatory element-binding protein-independent lipogenic pathway.
The Journal of biological chemistry 2006;281(21):15013-20.
-
2006: Mu Ying; Zhang Jinnan; Zhang Shimin; Zhou Hong-Hao; Toma David; Ren Songrong; Huang Leaf; Yaramus Maria; Baum Andrew; Venkataramanan Raman; Xie Wen
Traditional Chinese medicines Wu Wei Zi (Schisandra chinensis Baill) and Gan Cao (Glycyrrhiza uralensis Fisch) activate pregnane X receptor and increase warfarin clearance in rats.
The Journal of pharmacology and experimental therapeutics 2006;316(3):1369-77.
-
2006: He Fengtian; Li Jiang; Mu Ying; Kuruba Ramalinga; Ma Zheng; Wilson Annette; Alber Sean; Jiang Yu; Stevens Troy; Watkins Simon; Pitt Bruce; Xie Wen; Li Song
Downregulation of endothelin-1 by farnesoid X receptor in vascular endothelial cells.
Circulation research 2006;98(2):192-9.
-
2006: Gong Haibiao; Singh Shivendra V; Singh Sharda P; Mu Ying; Lee Jung Hoon; Saini Simrat P S; Toma David; Ren Songrong; Kagan Valerian E; Day Billy W; Zimniak Piotr; Xie Wen
Orphan nuclear receptor pregnane X receptor sensitizes oxidative stress responses in transgenic mice and cancerous cells.
Molecular endocrinology (Baltimore, Md.) 2006;20(2):279-90.
-
2005: Zhou J; Zhang J; Xie W
Xenobiotic nuclear receptor-mediated regulation of UDP-glucuronosyl-transferases.
Current drug metabolism 2005;6(4):289-98.
-
2005: Mu Ying; Stephenson Corey R J; Kendall Christopher; Saini Simrat P S; Toma David; Ren Songrong; Cai Hongbo; Strom Stephen C; Day Billy W; Wipf Peter; Xie Wen
A pregnane X receptor agonist with unique species-dependent stereoselectivity and its implications in drug development.
Molecular pharmacology 2005;68(2):403-13.
-
2005: Saini Simrat P S; Mu Ying; Gong Haibiao; Toma David; Uppal Hirdesh; Ren Songrong; Li Song; Poloyac Samuel M; Xie Wen
Dual role of orphan nuclear receptor pregnane X receptor in bilirubin detoxification in mice.
Hepatology (Baltimore, Md.) 2005;41(3):497-505.
-
2005: Uppal Hirdesh; Toma David; Saini Simrat P S; Ren Songrong; Jones Thomas J; Xie Wen
Combined loss of orphan receptors PXR and CAR heightens sensitivity to toxic bile acids in mice.
Hepatology (Baltimore, Md.) 2005;41(1):168-76.
-
2005: Janjic Jelena M; Mu Ying; Kendall Christopher; Stephenson Corey R J; Balachandran Raghavan; Raccor Brianne S; Lu Ying; Zhu Guangyu; Xie Wen; Wipf Peter; Day Billy W
New antiestrogens from a library screen of homoallylic amides, allylic amides, and C-cyclopropylalkylamides.
Bioorganic & medicinal chemistry 2005;13(1):157-64.
-
2005: Gong Haibiao; Sinz Michael W; Feng Yan; Chen Taosheng; Venkataramanan Raman; Xie Wen
Animal models of xenobiotic receptors in drug metabolism and diseases.
Methods in enzymology 2005;400():598-618.
-
2004: Poloyac Samuel M; Tortorici Michael A; Przychodzin Danielle I; Reynolds Robert B; Xie Wen; Frye Reginald F; Zemaitis Michael A
The effect of isoniazid on CYP2E1- and CYP4A-mediated hydroxylation of arachidonic acid in the rat liver and kidney.
Drug metabolism and disposition: the biological fate of chemicals 2004;32(7):727-33.
-
2004: Xie Wen; Uppal Hirdesh; Saini Simrat P S; Mu Ying; Little Joanna M; Radominska-Pandya Anna; Zemaitis Michael A
Orphan nuclear receptor-mediated xenobiotic regulation in drug metabolism.
Drug discovery today 2004;9(10):442-9.
-
2004: Gong Haibiao; Xie Wen
Orphan nuclear receptors, PXR and LXR: new ligands and therapeutic potential.
Expert opinion on therapeutic targets 2004;8(1):49-54.
-
2004: Saini Simrat P S; Sonoda Junichiro; Xu Li; Toma David; Uppal Hirdesh; Mu Ying; Ren Songrong; Moore David D; Evans Ronald M; Xie Wen
A novel constitutive androstane receptor-mediated and CYP3A-independent pathway of bile acid detoxification.
Molecular pharmacology 2004;65(2):292-300.
-
2003: Rosenfeld John M; Vargas Reynaldo; Xie Wen; Evans Ronald M
Genetic profiling defines the xenobiotic gene network controlled by the nuclear receptor pregnane X receptor.
Molecular endocrinology (Baltimore, Md.) 2003;17(7):1268-82.
-
2003: Xie Wen; Yeuh Mei-Fei; Radominska-Pandya Anna; Saini Simrat P S; Negishi Yoichi; Bottroff Bobbie Sue; Cabrera Geraldine Y; Tukey Robert H; Evans Ronald M
Control of steroid, heme, and carcinogen metabolism by nuclear pregnane X receptor and constitutive androstane receptor.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(7):4150-5.
-
2003: Xie Wen; Uppal Hirdesh
Drug discovery perspective of chemical-driven mouse mutagenesis.
Drug discovery today 2003;8(5):199.
-
2003: Sonoda J; Rosenfeld J M; Xu L; Evans R M; Xie W
A nuclear receptor-mediated xenobiotic response and its implication in drug metabolism and host protection.
Current drug metabolism 2003;4(1):59-72.
-
2002: Sonoda Junichiro; Xie Wen; Rosenfeld John M; Barwick Joyce L; Guzelian Philip S; Evans Ronald M
Regulation of a xenobiotic sulfonation cascade by nuclear pregnane X receptor (PXR).
Proceedings of the National Academy of Sciences of the United States of America 2002;99(21):13801-6.
-
2002: Xie Wen; Evans Ronald M
Pharmaceutical use of mouse models humanized for the xenobiotic receptor.
Drug discovery today 2002;7(9):509-15.
-
2001: Xie W; Evans R M
Orphan nuclear receptors: the exotics of xenobiotics.
The Journal of biological chemistry 2001;276(41):37739-42.
-
2001: Shi Y; Downes M; Xie W; Kao H Y; Ordentlich P; Tsai C C; Hon M; Evans R M
Sharp, an inducible cofactor that integrates nuclear receptor repression and activation.
Genes & development 2001;15(9):1140-51.
-
2001: Xie W; Radominska-Pandya A; Shi Y; Simon C M; Nelson M C; Ong E S; Waxman D J; Evans R M
An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(6):3375-80.
-
2000: Xie W; Barwick J L; Simon C M; Pierce A M; Safe S; Blumberg B; Guzelian P S; Evans R M
Reciprocal activation of xenobiotic response genes by nuclear receptors SXR/PXR and CAR.
Genes & development 2000;14(23):3014-23.
-
2000: Xie W; Barwick J L; Downes M; Blumberg B; Simon C M; Nelson M C; Neuschwander-Tetri B A; Brunt E M; Guzelian P S; Evans R M
Humanized xenobiotic response in mice expressing nuclear receptor SXR.
Nature 2000;406(6794):435-9.
-
1999: Xie W; Hong H; Yang N N; Lin R J; Simon C M; Stallcup M R; Evans R M
Constitutive activation of transcription and binding of coactivator by estrogen-related receptors 1 and 2.
Molecular endocrinology (Baltimore, Md.) 1999;13(12):2151-62.
-
1999: Chen H; Lin R J; Xie W; Wilpitz D; Evans R M
Regulation of hormone-induced histone hyperacetylation and gene activation via acetylation of an acetylase.
Cell 1999;98(5):675-86.
-
1999: Ordentlich P; Downes M; Xie W; Genin A; Spinner N B; Evans R M
Unique forms of human and mouse nuclear receptor corepressor SMRT.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(6):2639-44.
Sign-in to see more
