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Xiaohua Xin

Research Profile

Chemicals & Drugs

Procedures

Xenograft Model Antitumor Assays

Living Beings

Phenomena

Phosphorylation

Anatomy

Tumor Cells, Cultured

Physiology

Concepts & Ideas

Kinetics

Co-author Network

Publications

TOP 3
Xiaohua Xin; Tinya J Abrams; Paul W Hollenbach; Katherine G Rendahl; Yan Tang; Yoko Oei; Millicent G Embry; Debbie E Swinarski; Evelyn N Garrett; Nancy K Pryer; Suzanne Trudel; Bahija Jallal; Dirk B Mendel; Carla Heise
CHIR-258 is efficacious in a newly developed fibroblast growth factor receptor 3-expressing orthotopic multiple myeloma model in mice.
Dirk B Mendel; A Douglas Laird; Xiaohua Xin; Sharianne G Louie; James G Christensen; Guangmin Li; Randall E Schreck; Tinya J Abrams; Theresa J Ngai; Leslie B Lee; Lesley J Murray; Jeremy Carver; Emily Chan; Katherine G Moss; Joshua O Haznedar; Juthamas Sukbuntherng; Robert Blake; Li Sun; Cho Tang; Todd Miller; Sheri Shirazian; Gerald McMahon; Julie M Cherrington
In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: determination of a pharmacokinetic/pharmacodynamic relationship.
A Douglas Laird; James G Christensen; Guangmin Li; Jeremy Carver; Kimberly Smith; Xiaohua Xin; Katherine G Moss; Sharianne G Louie; Dirk B Mendel; Julie M Cherrington
SU6668 inhibits Flk-1/KDR and PDGFRbeta in vivo, resulting in rapid apoptosis of tumor vasculature and tumor regression in mice.

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All Publications

2006: Xiaohua Xin; Tinya J Abrams; Paul W Hollenbach; Katherine G Rendahl; Yan Tang; Yoko Oei; Millicent G Embry; Debbie E Swinarski; Evelyn N Garrett; Nancy K Pryer; Suzanne Trudel; Bahija Jallal; Dirk B Mendel; Carla Heise
CHIR-258 is efficacious in a newly developed fibroblast growth factor receptor 3-expressing orthotopic multiple myeloma model in mice.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(16):4908-15.
2003: Dirk B Mendel; A Douglas Laird; Xiaohua Xin; Sharianne G Louie; James G Christensen; Guangmin Li; Randall E Schreck; Tinya J Abrams; Theresa J Ngai; Leslie B Lee; Lesley J Murray; Jeremy Carver; Emily Chan; Katherine G Moss; Joshua O Haznedar; Juthamas Sukbuntherng; Robert Blake; Li Sun; Cho Tang; Todd Miller; Sheri Shirazian; Gerald McMahon; Julie M Cherrington
In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: determination of a pharmacokinetic/pharmacodynamic relationship.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(1):327-37.
2002: A Douglas Laird; James G Christensen; Guangmin Li; Jeremy Carver; Kimberly Smith; Xiaohua Xin; Katherine G Moss; Sharianne G Louie; Dirk B Mendel; Julie M Cherrington
SU6668 inhibits Flk-1/KDR and PDGFRbeta in vivo, resulting in rapid apoptosis of tumor vasculature and tumor regression in mice.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(7):681-90.