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Hong Xu

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Hong Xu; Larry D Bozulic; Deborah M Ramsey; Shengli Wu; Suzanne Ildstad
Simultaneous bone marrow and composite tissue transplantation in rats treated with nonmyeloablative conditioning promotes tolerance.
Bo Chen; Deborah R Corbin; Hong Xu; Suzanne Ildstad
A clinically feasible approach to induce delayed tolerance in recipients of prior kidney or vascularized composite allotransplants.
Hong Xu; Suzanne T Ildstad
Transplantation: is donor T-cell engraftment a biomarker for tolerance?

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All Publications

2013: Hong Xu; Larry D Bozulic; Deborah M Ramsey; Shengli Wu; Suzanne Ildstad
Simultaneous bone marrow and composite tissue transplantation in rats treated with nonmyeloablative conditioning promotes tolerance.
Transplantation 2013;95(2):301-8.
2012: Bo Chen; Deborah R Corbin; Hong Xu; Suzanne Ildstad
A clinically feasible approach to induce delayed tolerance in recipients of prior kidney or vascularized composite allotransplants.
Transplantation 2012;94(7):671-8.
2012: Hong Xu; Suzanne T Ildstad
Transplantation: is donor T-cell engraftment a biomarker for tolerance?
Nature reviews. Nephrology 2012;8(10):560-1.
2012: Hong Xu; Jun Yan; Ziqiang Zhu; Larry D Bozulic; Yiming Huang; Lala-Rukh Hussain; Suzanne Ildstad
Innate and adaptive immune responses are tolerized in chimeras prepared with nonmyeloablative conditioning.
Transplantation 2012;93(5):469-76.
2012: Joseph Leventhal; Hong Xu; Idona Goode; Yiming Huang; Suzanne T Ildstad
Novel regulatory therapies for prevention of Graft-versus-host disease.
BMC medicine 2012;10():48.
2011: Larry D Bozulic; Yiming Huang; Yujie Wen; Hong Xu; Suzanne Ildstad
Differential outcomes in prediabetic vs. overtly diabetic NOD mice nonmyeloablatively conditioned with costimulatory blockade.
Experimental hematology 2011;39(10):977-85.
2011: Shengli Wu; Hong Xu; Hong Zhao; Bo Chen; Olayemi M Ikusika; Ashley Ocker; Yujie Wen; Suzanne Ildstad
Sensitized recipients exhibit accelerated but not hyperacute rejection of vascularized composite tissue allografts.
Transplantation 2011;92(6):627-33.
2011: Larry D Bozulic; Yujie Wen; Hong Xu; Suzanne Ildstad
Evidence that FoxP3+ regulatory T cells may play a role in promoting long-term acceptance of composite tissue allotransplants.
Transplantation 2011;91(8):908-15.
2011: Yiming Huang; Larry D Bozulic; Thomas Miller; Hong Xu; Lala-Rukh Hussain; Suzanne Ildstad
CD8α+ plasmacytoid precursor DCs induce antigen-specific regulatory T cells that enhance HSC engraftment in vivo.
Blood 2011;117(8):2494-505.
2010: Hong Xu; Yiming Huang; L R Hussain; Z Zhu; Larry D Bozulic; C Ding; Jun Yan; Suzanne Ildstad
Sensitization to minor antigens is a significant barrier in bone marrow transplantation and is prevented by CD154:CD40 blockade.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2010;10(7):1569-79.
2010: Yiming Huang; Magda Kucia; Lala-Rukh Hussain; Yujie Wen; Hong Xu; Jun Yan; Mariusz Z Ratajczak; Suzanne Ildstad
Bone marrow transplantation temporarily improves pancreatic function in streptozotocin-induced diabetes: potential involvement of very small embryonic-like cells.
Transplantation 2010;89(6):677-85.
2009: Kadiyala V Ravindra; S Wu; M McKinney; Hong Xu; Suzanne Ildstad
Composite tissue allotransplantation: current challenges.
Transplantation proceedings 2009;41(9):3519-28.
2009: Dina N Rahhal; Hong Xu; Wei-Chao Huang; Shengli Wu; Yujie Wen; Yiming Huang; Suzanne Ildstad
Dissociation between peripheral blood chimerism and tolerance to hindlimb composite tissue transplants: preferential localization of chimerism in donor bone.
Transplantation 2009;88(6):773-81.
2009: S Wu; Hong Xu; Kadiyala V Ravindra; Suzanne Ildstad
Composite tissue allotransplantation: past, present and future-the history and expanding applications of CTA as a new frontier in transplantation.
Transplantation proceedings 2009;41(2):463-5.
2008: Bruce Swearingen; Kadiyala V Ravindra; Hong Xu; Shengli Wu; Warren C Breidenbach; Suzanne Ildstad
Science of composite tissue allotransplantation.
Transplantation 2008;86(5):627-35.
2008: Yiming Huang; Isabelle Fugier-Vivier; Thomas Miller; Mary J Elliott; Hong Xu; Larry D Bozulic; Paula M Chilton; Suzanne Ildstad
Plasmacytoid precursor dendritic cells from NOD mice exhibit impaired function: are they a component of diabetes pathogenesis?
Diabetes 2008;57(9):2360-70.
2008: Kadiyala V Ravindra; S Wu; Larry D Bozulic; Hong Xu; Warren C Breidenbach; Suzanne Ildstad
Composite tissue transplantation: a rapidly advancing field.
Transplantation proceedings 2008;40(5):1237-48.
2008: Yiming Huang; Mariusz Z Ratajczak; Ryan Reca; Hong Xu; Michael Tanner; Francine Rezzoug; Lala-Rukh Hussain; Isabelle Fugier-Vivier; Roberto Bolli; Suzanne Ildstad
Fms-related tyrosine kinase 3 expression discriminates hematopoietic stem cells subpopulations with differing engraftment-potential: identifying the most potent combination.
Transplantation 2008;85(8):1175-84.
2008: Hong Xu; Jun Yan; Yiming Huang; Paula M Chilton; Chuanlin Ding; Carrie L Schanie; Li Wang; Suzanne Ildstad
Costimulatory blockade of CD154-CD40 in combination with T-cell lymphodepletion results in prevention of allogeneic sensitization.
Blood 2008;111(6):3266-75.
2007: Hong Xu; Paula M Chilton; Yiming Huang; Carrie L Schanie; Jun Yan; Suzanne Ildstad
Addition of cyclophosphamide to T-cell depletion-based nonmyeloablative conditioning allows donor T-cell engraftment and clonal deletion of alloreactive host T-cells after bone marrow transplantation.
Transplantation 2007;83(7):954-63.
2007: Larry A Adamson; Wei-Chao Huang; Warren C Breidenbach; Dina Rahhal; Hong Xu; Yiming Huang; Diane J Pidwell; Fu-Chan Wei; Gordon Tobin; Suzanne Ildstad
A modified model of hindlimb osteomyocutaneous flap for the study of tolerance to composite tissue allografts.
Microsurgery 2007;27(7):630-6.
2006: Hong Xu; Paula M Chilton; Michael K Tanner; Yiming Huang; Carrie L Schanie; Mariano Dy-Liacco; Jun Yan; Suzanne Ildstad
Humoral immunity is the dominant barrier for allogeneic bone marrow engraftment in sensitized recipients.
Blood 2006;108(10):3611-9.
2006: Yiming Huang; Magda Kucia; Francine Rezzoug; Janina Ratajczak; Michael K Tanner; Mariusz Z Ratajczak; Carrie L Schanie; Hong Xu; Isabelle Fugier-Vivier; Suzanne Ildstad
Flt3-ligand-mobilized peripheral blood, but not Flt3-ligand-expanded bone marrow, facilitating cells promote establishment of chimerism and tolerance.
Stem cells (Dayton, Ohio) 2006;24(4):936-48.
2005: Yiming Huang; Francine Rezzoug; Hong Xu; Paula M Chilton; Carrie L Schanie; Isabelle Fugier-Vivier; Suzanne Ildstad
NK cells play a critical role in the regulation of class I-deficient hemopoietic stem cell engraftment: evidence for NK tolerance correlates with receptor editing.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(6):3753-61.
2005: Suzanne Ildstad; Paula M Chilton; Hong Xu; Michele A Domenick; Mukunda B Ray
Preconditioning of NOD mice with anti-CD8 mAb and costimulatory blockade enhances chimerism and tolerance and prevents diabetes, while depletion of alpha beta-TCR+ and CD4+ cells negates the effect.
Blood 2005;105(6):2577-84.
2005: Isabelle Fugier-Vivier; Francine Rezzoug; Yiming Huang; Amanda J Graul-Layman; Carrie L Schanie; Hong Xu; Paula M Chilton; Suzanne Ildstad
Plasmacytoid precursor dendritic cells facilitate allogeneic hematopoietic stem cell engraftment.
The Journal of experimental medicine 2005;201(3):373-83.
2004: Paula M Chilton; Francine Rezzoug; Isabelle Fugier-Vivier; Leslie A Weeter; Hong Xu; Yiming Huang; Mukunda B Ray; Suzanne Ildstad
Flt3-ligand treatment prevents diabetes in NOD mice.
Diabetes 2004;53(8):1995-2002.
2004: Hong Xu; Beate G Exner; Paula M Chilton; Michael K Tanner; Yvonne M Mueller; Francine Rezzoug; Suzanne Ildstad
A delay in bone marrow transplantation after partial conditioning improves engraftment.
Transplantation 2004;77(6):819-26.
2004: Hong Xu; Paula M Chilton; Yiming Huang; Carrie L Schanie; Suzanne Ildstad
Production of donor T cells is critical for induction of donor-specific tolerance and maintenance of chimerism.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(3):1463-71.
2004: Hong Xu; Beate G Exner; Paula M Chilton; Carrie L Schanie; Suzanne Ildstad
CD45 congenic bone marrow transplantation: evidence for T cell-mediated immunity.
Stem cells (Dayton, Ohio) 2004;22(6):1039-48.
2002: Hong Xu; Beate G Exner; Daniel E Cramer; Michael K Tanner; Yvonne M Mueller; Suzanne Ildstad
CD8(+), alphabeta-TCR(+), and gammadelta-TCR(+) cells in the recipient hematopoietic environment mediate resistance to engraftment of allogeneic donor bone marrow.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(4):1636-43.